locus-tag	class	description
DVK44_RS00015	COG0387	Pfam Sodium calcium exchanger
DVK44_RS00030	COG0515	serine threonine protein kinase
DVK44_RS00035	COG3866	Pectate lyase
DVK44_RS00040	COG1793	dna ligase
DVK44_RS00080	COG2813	Specifically methylates the guanine in position
DVK44_RS00120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DVK44_RS00120	COG1796	DNA polymerase
DVK44_RS00150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVK44_RS00155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS00160	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS00180	COG2205	protein histidine kinase activity
DVK44_RS00185	COG0745	RESPONSE REGULATOR receiver
DVK44_RS00235	COG3401	FG-GAP repeat protein
DVK44_RS00260	COG0395	ABC-type sugar transport system, permease component
DVK44_RS00265	COG1175	transmembrane transport
DVK44_RS00275	COG1802	Transcriptional regulator
DVK44_RS00280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DVK44_RS00295	COG0395	ABC-type sugar transport system, permease component
DVK44_RS00310	COG4677	pectinesterase activity
DVK44_RS00320	COG2755	lipolytic protein G-D-S-L family
DVK44_RS00360	COG2233	PERMEase
DVK44_RS00395	COG2318	DinB family
DVK44_RS00410	COG4585	Histidine kinase
DVK44_RS00415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DVK44_RS00420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DVK44_RS00425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DVK44_RS00435	COG0765	amino acid transport
DVK44_RS00460	COG2267	carboxylic ester hydrolase activity
DVK44_RS00485	COG1609	Transcriptional regulator
DVK44_RS00490	COG3250	beta-galactosidase activity
DVK44_RS00520	COG4608	Belongs to the ABC transporter superfamily
DVK44_RS00525	COG0444	Belongs to the ABC transporter superfamily
DVK44_RS00530	COG0596	Alpha beta hydrolase
DVK44_RS00540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS00565	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS00615	COG2318	DinB family
DVK44_RS00625	COG0640	Transcriptional regulator
DVK44_RS00630	COG0346	lactoylglutathione lyase activity
DVK44_RS00635	COG2376	Dihydroxyacetone kinase
DVK44_RS00640	COG1461	Dihydroxyacetone kinase
DVK44_RS00660	COG0475	glutathione-regulated potassium exporter activity
DVK44_RS00675	COG3851	Histidine kinase
DVK44_RS00680	COG2197	response regulator
DVK44_RS00745	COG1755	Isoprenylcysteine carboxyl methyltransferase
DVK44_RS00765	COG3594	Acyltransferase
DVK44_RS00790	COG0586	Pfam SNARE associated Golgi protein
DVK44_RS00800	COG0671	phosphoesterase, PA-phosphatase related
DVK44_RS00850	COG1316	TRANSCRIPTIONal
DVK44_RS00895	COG4733	cellulase activity
DVK44_RS00895	COG5297	Belongs to the glycosyl hydrolase family 6
DVK44_RS00905	COG5297	Belongs to the glycosyl hydrolase family 6
DVK44_RS00910	COG0515	serine threonine protein kinase
DVK44_RS00920	COG1132	(ABC) transporter
DVK44_RS00925	COG1132	(ABC) transporter
DVK44_RS00930	COG2197	response regulator
DVK44_RS00935	COG0501	Belongs to the peptidase M48B family
DVK44_RS00945	COG3386	PFAM SMP-30 Gluconolaconase
DVK44_RS00955	COG3655	Transcriptional regulator
DVK44_RS00965	COG1609	Transcriptional regulator
DVK44_RS00970	COG4209	transmembrane transport
DVK44_RS00975	COG0395	ABC-type sugar transport system, permease component
DVK44_RS00995	COG3250	beta-galactosidase activity
DVK44_RS01005	COG1175	transmembrane transport
DVK44_RS01050	COG1070	Carbohydrate kinase
DVK44_RS01055	COG1349	DNA-binding transcription factor activity
DVK44_RS01075	COG0395	ABC-type sugar transport system, permease component
DVK44_RS01080	COG1175	transmembrane transport
DVK44_RS01090	COG3250	beta-galactosidase activity
DVK44_RS01095	COG3540	Alkaline phosphatase
DVK44_RS01110	COG1113	amino acid transport
DVK44_RS01115	COG2186	Transcriptional regulator
DVK44_RS01120	COG2175	clavaminate synthase activity
DVK44_RS01125	COG0242	peptide deformylase activity
DVK44_RS01140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DVK44_RS01180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DVK44_RS01210	COG0464	growth
DVK44_RS01220	COG1349	DNA-binding transcription factor activity
DVK44_RS01265	COG1940	carbohydrate kinase activity
DVK44_RS01270	COG2223	nitrite transmembrane transporter activity
DVK44_RS01295	COG2318	DinB family
DVK44_RS01305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS01310	COG1660	Displays ATPase and GTPase activities
DVK44_RS01335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DVK44_RS01375	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS01385	COG0584	glycerophosphoryl diester phosphodiesterase
DVK44_RS01435	COG0640	Transcriptional regulator
DVK44_RS01450	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DVK44_RS01455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS01470	COG1802	Transcriptional regulator
DVK44_RS01475	COG1126	abc transporter atp-binding protein
DVK44_RS01485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DVK44_RS01490	COG1902	pentaerythritol trinitrate reductase activity
DVK44_RS01510	COG1063	alcohol dehydrogenase
DVK44_RS01515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DVK44_RS01530	COG3509	depolymerase
DVK44_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS01560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS01560	COG3321	synthase
DVK44_RS01560	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS01560	COG0300	oxidoreductase activity
DVK44_RS01565	COG2175	clavaminate synthase activity
DVK44_RS01575	COG1129	ABC transporter
DVK44_RS01580	COG1879	ABC-type sugar transport system periplasmic component
DVK44_RS01585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS01590	COG1869	D-ribose catabolic process
DVK44_RS01605	COG1113	amino acid transport
DVK44_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS01630	COG0745	RESPONSE REGULATOR receiver
DVK44_RS01635	COG1846	Transcriptional regulator
DVK44_RS01645	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS01655	COG2197	response regulator
DVK44_RS01665	COG4171	peptide transport system, permease
DVK44_RS01695	COG0640	Transcriptional regulator
DVK44_RS01700	COG2814	Major facilitator Superfamily
DVK44_RS01720	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DVK44_RS01745	COG2124	cytochrome p450
DVK44_RS01765	COG2124	cytochrome p450
DVK44_RS01770	COG2197	response regulator
DVK44_RS01775	COG0667	Aldo Keto reductase
DVK44_RS01830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DVK44_RS01840	COG2072	flavoprotein involved in K transport
DVK44_RS01850	COG1132	(ABC) transporter
DVK44_RS01860	COG1132	(ABC) transporter
DVK44_RS01865	COG1132	(ABC) transporter
DVK44_RS01885	COG1946	Acyl-CoA thioesterase
DVK44_RS01915	COG0386	Belongs to the glutathione peroxidase family
DVK44_RS01920	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS01930	COG0242	peptide deformylase activity
DVK44_RS01940	COG3442	glutamine amidotransferase
DVK44_RS01945	COG0205	6-phosphofructokinase activity
DVK44_RS01955	COG0148	phosphopyruvate hydratase activity
DVK44_RS01995	COG0829	nickel cation binding
DVK44_RS02000	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DVK44_RS02010	COG0804	urea catabolic process
DVK44_RS02015	COG0832	Belongs to the urease beta subunit family
DVK44_RS02020	COG0831	urea catabolic process
DVK44_RS02030	COG0740	serine-type endopeptidase activity
DVK44_RS02060	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DVK44_RS02065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DVK44_RS02070	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DVK44_RS02085	COG0395	ABC-type sugar transport system, permease component
DVK44_RS02090	COG1175	transmembrane transport
DVK44_RS02100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DVK44_RS02130	COG1278	Cold shock
DVK44_RS02135	COG0456	acetyltransferase
DVK44_RS02155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DVK44_RS02160	COG3663	DNA glycosylase
DVK44_RS02165	COG1609	Transcriptional regulator
DVK44_RS02170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DVK44_RS02175	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS02180	COG0246	Mannitol dehydrogenase
DVK44_RS02185	COG1063	alcohol dehydrogenase
DVK44_RS02190	COG0477	Major facilitator Superfamily
DVK44_RS02195	COG1940	carbohydrate kinase activity
DVK44_RS02200	COG2188	Transcriptional regulator
DVK44_RS02205	COG1595	DNA-templated transcription, initiation
DVK44_RS02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVK44_RS02260	COG0420	3'-5' exonuclease activity
DVK44_RS02265	COG1739	Uncharacterized protein family UPF0029
DVK44_RS02270	COG1832	CoA-binding protein
DVK44_RS02335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DVK44_RS02360	COG1968	undecaprenyl-diphosphatase activity
DVK44_RS02390	COG0464	growth
DVK44_RS02500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DVK44_RS02505	COG0673	inositol 2-dehydrogenase activity
DVK44_RS02520	COG2318	DinB family
DVK44_RS02535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DVK44_RS02620	COG1489	DNA binding
DVK44_RS02625	COG3321	synthase
DVK44_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS02625	COG0604	alcohol dehydrogenase
DVK44_RS02640	COG0395	ABC-type sugar transport system, permease component
DVK44_RS02645	COG1175	transmembrane transport
DVK44_RS02655	COG1609	Transcriptional regulator
DVK44_RS02660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS02665	COG1609	Transcriptional regulator
DVK44_RS02670	COG3250	beta-galactosidase activity
DVK44_RS02675	COG0367	asparagine synthase
DVK44_RS02680	COG2124	cytochrome p450
DVK44_RS02685	COG1132	(ABC) transporter
DVK44_RS02710	COG1120	ATPase activity
DVK44_RS02745	COG0697	spore germination
DVK44_RS02770	COG1695	Transcriptional regulator
DVK44_RS02780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DVK44_RS02790	COG0477	Major facilitator Superfamily
DVK44_RS02835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DVK44_RS02835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DVK44_RS02845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DVK44_RS02865	COG1716	ATPase activity
DVK44_RS02885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DVK44_RS02915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DVK44_RS02925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DVK44_RS02940	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DVK44_RS02955	COG2018	Roadblock/LC7 domain
DVK44_RS02990	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS02995	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVK44_RS03035	COG2270	Major facilitator Superfamily
DVK44_RS03050	COG1216	Glycosyl transferase, family 2
DVK44_RS03060	COG1522	sequence-specific DNA binding
DVK44_RS03070	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS03115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DVK44_RS03120	COG0140	phosphoribosyl-ATP diphosphatase activity
DVK44_RS03125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DVK44_RS03130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DVK44_RS03130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DVK44_RS03135	COG3201	nicotinamide mononucleotide transporter
DVK44_RS03150	COG1940	carbohydrate kinase activity
DVK44_RS03150	COG1846	Transcriptional regulator
DVK44_RS03155	COG0738	Major facilitator superfamily
DVK44_RS03170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DVK44_RS03185	COG2390	Transcriptional regulator
DVK44_RS03190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DVK44_RS03200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DVK44_RS03215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DVK44_RS03225	COG1758	RNA polymerase activity
DVK44_RS03230	COG0194	GDP metabolic process
DVK44_RS03240	COG0284	orotidine-5'-phosphate decarboxylase activity
DVK44_RS03245	COG0167	dihydroorotate dehydrogenase activity
DVK44_RS03250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DVK44_RS03255	COG0505	Belongs to the CarA family
DVK44_RS03265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DVK44_RS03270	COG0540	Belongs to the ATCase OTCase family
DVK44_RS03275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DVK44_RS03285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DVK44_RS03290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DVK44_RS03295	COG0006	proline dipeptidase activity
DVK44_RS03305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DVK44_RS03310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DVK44_RS03315	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DVK44_RS03320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DVK44_RS03325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DVK44_RS03330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DVK44_RS03335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DVK44_RS03350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DVK44_RS03375	COG0124	histidyl-tRNA synthetase
DVK44_RS03390	COG1196	nuclear chromosome segregation
DVK44_RS03395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DVK44_RS03400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DVK44_RS03405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DVK44_RS03410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DVK44_RS03420	COG2255	four-way junction helicase activity
DVK44_RS03425	COG0632	four-way junction helicase activity
DVK44_RS03430	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DVK44_RS03435	COG0217	transcriptional regulatory protein
DVK44_RS03440	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DVK44_RS03445	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DVK44_RS03455	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS03460	COG1560	Kdo2-lipid A biosynthetic process
DVK44_RS03465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DVK44_RS03480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DVK44_RS03485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DVK44_RS03525	COG0454	-acetyltransferase
DVK44_RS03525	COG0456	acetyltransferase
DVK44_RS03535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DVK44_RS03575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DVK44_RS03580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DVK44_RS03580	COG1648	precorrin-2 dehydrogenase activity
DVK44_RS03585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DVK44_RS03600	COG1464	Belongs to the NlpA lipoprotein family
DVK44_RS03605	COG1464	Belongs to the NlpA lipoprotein family
DVK44_RS03610	COG2011	ABC-type metal ion transport system permease component
DVK44_RS03615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DVK44_RS03650	COG0204	Acyl-transferase
DVK44_RS03650	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS03655	COG0477	Major facilitator Superfamily
DVK44_RS03670	COG0165	Argininosuccinate lyase
DVK44_RS03675	COG0137	argininosuccinate synthase activity
DVK44_RS03710	COG1438	arginine binding
DVK44_RS03715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS03725	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DVK44_RS03730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DVK44_RS03790	COG0514	ATP-dependent DNA helicase (RecQ)
DVK44_RS03795	COG0673	inositol 2-dehydrogenase activity
DVK44_RS03800	COG1940	carbohydrate kinase activity
DVK44_RS03810	COG1175	transmembrane transport
DVK44_RS03815	COG0395	ABC-type sugar transport system, permease component
DVK44_RS03835	COG0697	spore germination
DVK44_RS03840	COG1649	PFAM Uncharacterised BCR, COG1649
DVK44_RS03850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DVK44_RS03870	COG1051	belongs to the nudix hydrolase family
DVK44_RS03885	COG0072	phenylalanine-tRNA ligase activity
DVK44_RS03885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DVK44_RS03890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DVK44_RS03895	COG5002	protein histidine kinase activity
DVK44_RS03900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DVK44_RS03905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DVK44_RS03910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DVK44_RS03915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DVK44_RS03950	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS03955	COG0174	glutamine synthetase
DVK44_RS03960	COG2186	Transcriptional regulator
DVK44_RS03965	COG0531	amino acid
DVK44_RS03970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DVK44_RS03995	COG4175	Glycine betaine
DVK44_RS03995	COG0517	IMP dehydrogenase activity
DVK44_RS04000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DVK44_RS04010	COG1595	DNA-templated transcription, initiation
DVK44_RS04025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DVK44_RS04055	COG1309	transcriptional regulator
DVK44_RS04065	COG3665	Urea carboxylase-associated protein
DVK44_RS04085	COG0805	protein transport
DVK44_RS04090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVK44_RS04125	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DVK44_RS04135	COG1609	Transcriptional regulator
DVK44_RS04140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DVK44_RS04145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DVK44_RS04160	COG4122	O-methyltransferase activity
DVK44_RS04165	COG1222	aaa ATPase
DVK44_RS04185	COG0517	IMP dehydrogenase activity
DVK44_RS04185	COG1994	Peptidase M50
DVK44_RS04195	COG2197	response regulator
DVK44_RS04200	COG4166	transmembrane transport
DVK44_RS04210	COG0646	methionine synthase
DVK44_RS04210	COG1410	methionine synthase
DVK44_RS04215	COG1414	Transcriptional regulator
DVK44_RS04220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DVK44_RS04225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DVK44_RS04230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DVK44_RS04235	COG2186	Transcriptional regulator
DVK44_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS04245	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS04260	COG0215	cysteine-tRNA ligase activity
DVK44_RS04280	COG0598	Magnesium transport protein CorA
DVK44_RS04285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS04290	COG0667	Aldo Keto reductase
DVK44_RS04320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS04370	COG0564	pseudouridine synthase activity
DVK44_RS04385	COG2186	Transcriptional regulator
DVK44_RS04390	COG3265	gluconokinase activity
DVK44_RS04410	COG3573	Dehydrogenase
DVK44_RS04415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DVK44_RS04420	COG2149	membrane
DVK44_RS04445	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS04460	COG1216	Glycosyl transferase, family 2
DVK44_RS04465	COG0667	Aldo Keto reductase
DVK44_RS04475	COG1215	transferase activity, transferring glycosyl groups
DVK44_RS04480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DVK44_RS04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DVK44_RS04500	COG4585	Histidine kinase
DVK44_RS04505	COG2197	response regulator
DVK44_RS04515	COG3876	Protein conserved in bacteria
DVK44_RS04520	COG1051	belongs to the nudix hydrolase family
DVK44_RS04575	COG3842	ATPase activity
DVK44_RS04580	COG1309	transcriptional regulator
DVK44_RS04585	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DVK44_RS04590	COG2188	Transcriptional regulator
DVK44_RS04600	COG2755	lipolytic protein G-D-S-L family
DVK44_RS04605	COG0463	Glycosyl transferase, family 2
DVK44_RS04610	COG1216	Glycosyl transferase, family 2
DVK44_RS04615	COG1649	PFAM Uncharacterised BCR, COG1649
DVK44_RS04615	COG0726	polysaccharide deacetylase
DVK44_RS04630	COG1725	Transcriptional regulator
DVK44_RS04640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS04675	COG2226	methyltransferase
DVK44_RS04680	COG2890	protein-(glutamine-N5) methyltransferase activity
DVK44_RS04700	COG0587	DNA-directed DNA polymerase activity
DVK44_RS04730	COG0641	radical SAM
DVK44_RS04760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS04780	COG1799	cell septum assembly
DVK44_RS04785	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS04795	COG0671	phosphoesterase, PA-phosphatase related
DVK44_RS04815	COG1160	GTP binding
DVK44_RS04825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DVK44_RS04845	COG3541	Predicted nucleotidyltransferase
DVK44_RS04855	COG1056	cytidyltransferase-related domain
DVK44_RS04855	COG1051	belongs to the nudix hydrolase family
DVK44_RS04860	COG1187	pseudouridine synthase activity
DVK44_RS04865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DVK44_RS04870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DVK44_RS04885	COG0686	Belongs to the AlaDH PNT family
DVK44_RS04900	COG0494	nUDIX hydrolase
DVK44_RS04905	COG0504	CTP synthase activity
DVK44_RS04910	COG3387	PFAM Glycoside hydrolase 15-related
DVK44_RS04920	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS04925	COG0497	DNA recombination
DVK44_RS04930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DVK44_RS04950	COG1120	ATPase activity
DVK44_RS04955	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS04960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS04970	COG0647	UMP catabolic process
DVK44_RS05000	COG2094	Belongs to the DNA glycosylase MPG family
DVK44_RS05030	COG1119	ATPase activity
DVK44_RS05045	COG2197	response regulator
DVK44_RS05050	COG4585	Histidine kinase
DVK44_RS05055	COG4221	oxidoreductase activity
DVK44_RS05070	COG0842	Transport permease protein
DVK44_RS05070	COG1131	(ABC) transporter
DVK44_RS05070	COG1716	ATPase activity
DVK44_RS05075	COG3830	Belongs to the UPF0237 family
DVK44_RS05075	COG0560	Phosphoserine phosphatase
DVK44_RS05090	COG2807	transmembrane transport
DVK44_RS05095	COG2186	Transcriptional regulator
DVK44_RS05100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DVK44_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS05125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DVK44_RS05130	COG2261	transglycosylase associated protein
DVK44_RS05145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DVK44_RS05150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DVK44_RS05185	COG3387	PFAM Glycoside hydrolase 15-related
DVK44_RS05235	COG0488	(ABC) transporter
DVK44_RS05265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DVK44_RS05270	COG1492	cobalamin metabolic process
DVK44_RS05285	COG1797	cobyrinic acid a,c-diamide synthase activity
DVK44_RS05320	COG0181	hydroxymethylbilane synthase activity
DVK44_RS05340	COG1902	pentaerythritol trinitrate reductase activity
DVK44_RS05345	COG1846	Transcriptional regulator
DVK44_RS05365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS05370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS05375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVK44_RS05390	COG1414	Transcriptional regulator
DVK44_RS05395	COG0768	penicillin binding
DVK44_RS05405	COG3842	ATPase activity
DVK44_RS05410	COG1176	ABC-type spermidine putrescine transport system, permease component I
DVK44_RS05415	COG1177	transmembrane transport
DVK44_RS05430	COG0154	amidase activity
DVK44_RS05455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DVK44_RS05485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DVK44_RS05490	COG2171	N-acyltransferase activity
DVK44_RS05500	COG3226	Transcriptional regulator
DVK44_RS05505	COG2076	Multidrug Resistance protein
DVK44_RS05530	COG1733	regulation of RNA biosynthetic process
DVK44_RS05540	COG4221	oxidoreductase activity
DVK44_RS05555	COG2151	metal-sulfur cluster biosynthetic enzyme
DVK44_RS05560	COG0822	iron-sulfur transferase activity
DVK44_RS05565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DVK44_RS05570	COG0396	ATPase activity
DVK44_RS05580	COG0719	Fe-S assembly protein
DVK44_RS05595	COG1131	(ABC) transporter
DVK44_RS05605	COG1612	heme a metabolic process
DVK44_RS05620	COG0109	protoheme IX farnesyltransferase activity
DVK44_RS05630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DVK44_RS05645	COG0363	glucosamine-6-phosphate deaminase activity
DVK44_RS05650	COG4195	phage-related replication protein
DVK44_RS05665	COG0166	Belongs to the GPI family
DVK44_RS05680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DVK44_RS05685	COG0149	triose-phosphate isomerase activity
DVK44_RS05690	COG0126	phosphoglycerate kinase activity
DVK44_RS05695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DVK44_RS05700	COG1481	regulation of sporulation
DVK44_RS05705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DVK44_RS05710	COG1660	Displays ATPase and GTPase activities
DVK44_RS05715	COG0322	excinuclease ABC activity
DVK44_RS05725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DVK44_RS05735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVK44_RS05755	COG0556	nucleotide-excision repair
DVK44_RS05765	COG0584	glycerophosphoryl diester phosphodiesterase
DVK44_RS05770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DVK44_RS05775	COG1063	alcohol dehydrogenase
DVK44_RS05780	COG2313	pseudouridylate synthase activity
DVK44_RS05805	COG0436	Aminotransferase
DVK44_RS05835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DVK44_RS05840	COG0330	HflC and HflK could
DVK44_RS05850	COG2226	methyltransferase
DVK44_RS05865	COG0237	dephospho-CoA kinase activity
DVK44_RS05885	COG2226	methyltransferase
DVK44_RS05890	COG1643	Atp-dependent helicase
DVK44_RS05910	COG2050	protein possibly involved in aromatic compounds catabolism
DVK44_RS05975	COG1605	Chorismate mutase
DVK44_RS05975	COG0287	Prephenate dehydrogenase
DVK44_RS06010	COG2732	(Barnase) inhibitor
DVK44_RS06020	COG0513	Belongs to the DEAD box helicase family
DVK44_RS06025	COG1278	Cold shock
DVK44_RS06035	COG2318	DinB family
DVK44_RS06040	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DVK44_RS06065	COG0067	glutamate synthase
DVK44_RS06065	COG0069	glutamate synthase activity
DVK44_RS06065	COG0070	glutamate synthase
DVK44_RS06080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS06085	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DVK44_RS06095	COG0159	tryptophan synthase activity
DVK44_RS06100	COG0133	tryptophan synthase activity
DVK44_RS06110	COG0134	indole-3-glycerol-phosphate synthase activity
DVK44_RS06135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DVK44_RS06140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DVK44_RS06155	COG0107	imidazoleglycerol-phosphate synthase activity
DVK44_RS06160	COG0251	oxidation-reduction process
DVK44_RS06165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DVK44_RS06170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DVK44_RS06175	COG0131	Imidazoleglycerol-phosphate dehydratase
DVK44_RS06180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DVK44_RS06185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DVK44_RS06205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DVK44_RS06225	COG1432	Conserved Protein
DVK44_RS06235	COG0587	DNA-directed DNA polymerase activity
DVK44_RS06270	COG2153	protein acetylation
DVK44_RS06280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DVK44_RS06290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DVK44_RS06295	COG4336	lyase activity
DVK44_RS06300	COG0477	Major facilitator Superfamily
DVK44_RS06310	COG1984	allophanate hydrolase subunit 2
DVK44_RS06320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DVK44_RS06325	COG1802	Transcriptional regulator
DVK44_RS06335	COG3599	regulation of cell shape
DVK44_RS06345	COG1799	cell septum assembly
DVK44_RS06350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DVK44_RS06365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DVK44_RS06370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DVK44_RS06380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DVK44_RS06385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DVK44_RS06395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DVK44_RS06410	COG0275	rRNA processing
DVK44_RS06420	COG0714	Associated with various cellular activities
DVK44_RS06440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DVK44_RS06450	COG1233	COG1233 Phytoene dehydrogenase and related
DVK44_RS06465	COG0352	thiamine-phosphate diphosphorylase activity
DVK44_RS06485	COG2022	thiamine diphosphate biosynthetic process
DVK44_RS06485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DVK44_RS06495	COG2022	thiamine diphosphate biosynthetic process
DVK44_RS06500	COG2815	serine threonine protein kinase
DVK44_RS06500	COG0515	serine threonine protein kinase
DVK44_RS06505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DVK44_RS06510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DVK44_RS06515	COG2193	ferroxidase activity
DVK44_RS06525	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DVK44_RS06535	COG2197	response regulator
DVK44_RS06540	COG4585	Histidine kinase
DVK44_RS06565	COG1940	carbohydrate kinase activity
DVK44_RS06575	COG0003	Pfam Anion-transporting ATPase
DVK44_RS06590	COG1022	Amp-dependent synthetase and ligase
DVK44_RS06595	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS06615	COG1388	LysM domain
DVK44_RS06615	COG3103	Sh3 type 3 domain protein
DVK44_RS06615	COG0791	NLP P60 protein
DVK44_RS06630	COG0705	Rhomboid family
DVK44_RS06640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DVK44_RS06645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DVK44_RS06650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DVK44_RS06655	COG0723	plastoquinol--plastocyanin reductase activity
DVK44_RS06660	COG2010	Cytochrome c
DVK44_RS06665	COG1845	cytochrome c oxidase, subunit III
DVK44_RS06675	COG1376	ErfK ybiS ycfS ynhG family protein
DVK44_RS06685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DVK44_RS06690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DVK44_RS06700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS06715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DVK44_RS06720	COG1404	Belongs to the peptidase S8 family
DVK44_RS06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS06735	COG0596	Alpha beta hydrolase
DVK44_RS06745	COG1335	isochorismatase
DVK44_RS06755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DVK44_RS06760	COG2197	response regulator
DVK44_RS06765	COG4585	Histidine kinase
DVK44_RS06785	COG2226	methyltransferase
DVK44_RS06790	COG1132	(ABC) transporter
DVK44_RS06795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVK44_RS06810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DVK44_RS06815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DVK44_RS06815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DVK44_RS06830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DVK44_RS06835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DVK44_RS06845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DVK44_RS06850	COG0508	dehydrogenase complex catalyzes the overall conversion of
DVK44_RS06860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DVK44_RS06895	COG0321	lipoyl(octanoyl) transferase activity
DVK44_RS06900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DVK44_RS06930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DVK44_RS06935	COG0148	phosphopyruvate hydratase activity
DVK44_RS06940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DVK44_RS06945	COG1993	acr, cog1993
DVK44_RS06950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DVK44_RS06995	COG0745	RESPONSE REGULATOR receiver
DVK44_RS07045	COG0366	Alpha amylase catalytic
DVK44_RS07050	COG0395	ABC-type sugar transport system, permease component
DVK44_RS07055	COG1175	transmembrane transport
DVK44_RS07060	COG2182	Extracellular solute-binding protein
DVK44_RS07065	COG1609	Transcriptional regulator
DVK44_RS07080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DVK44_RS07105	COG0174	glutamine synthetase
DVK44_RS07110	COG1846	Transcriptional regulator
DVK44_RS07130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DVK44_RS07130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DVK44_RS07135	COG2814	Major facilitator Superfamily
DVK44_RS07150	COG0477	Major facilitator Superfamily
DVK44_RS07155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DVK44_RS07175	COG1994	Peptidase M50
DVK44_RS07220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DVK44_RS07255	COG0596	Alpha beta hydrolase
DVK44_RS07300	COG0583	DNA-binding transcription factor activity
DVK44_RS07325	COG4558	Periplasmic binding protein
DVK44_RS07330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS07335	COG1120	ATPase activity
DVK44_RS07345	COG2837	iron assimilation
DVK44_RS07350	COG0672	)-iron permease
DVK44_RS07370	COG1834	amidinotransferase
DVK44_RS07400	COG2814	Major facilitator Superfamily
DVK44_RS07410	COG1595	DNA-templated transcription, initiation
DVK44_RS07430	COG1136	(ABC) transporter
DVK44_RS07435	COG0577	efflux transmembrane transporter activity
DVK44_RS07435	COG1136	(ABC) transporter
DVK44_RS07510	COG1222	aaa ATPase
DVK44_RS07555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DVK44_RS07565	COG3022	response to hydroperoxide
DVK44_RS07570	COG0800	Aldolase
DVK44_RS07585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DVK44_RS07595	COG2197	response regulator
DVK44_RS07640	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS07660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DVK44_RS07675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS07690	COG0277	FAD linked oxidase domain protein
DVK44_RS07705	COG1657	PFAM Prenyltransferase squalene oxidase
DVK44_RS07720	COG4122	O-methyltransferase activity
DVK44_RS07735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVK44_RS07800	COG1175	transmembrane transport
DVK44_RS07805	COG3833	ABC-type maltose transport systems, permease component
DVK44_RS07810	COG1472	Belongs to the glycosyl hydrolase 3 family
DVK44_RS07830	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DVK44_RS07880	COG1358	cellular component organization or biogenesis
DVK44_RS07925	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DVK44_RS07940	COG4585	Histidine kinase
DVK44_RS07945	COG2197	response regulator
DVK44_RS07955	COG0667	Aldo Keto reductase
DVK44_RS07960	COG0789	Transcriptional regulator
DVK44_RS07965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DVK44_RS07985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVK44_RS07990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS07995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DVK44_RS08050	COG3940	Belongs to the glycosyl hydrolase 43 family
DVK44_RS08055	COG3507	Belongs to the glycosyl hydrolase 43 family
DVK44_RS08080	COG2130	NADP-dependent
DVK44_RS08125	COG1742	UPF0060 membrane protein
DVK44_RS08140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DVK44_RS08145	COG0798	PFAM Bile acid sodium symporter
DVK44_RS08155	COG2205	protein histidine kinase activity
DVK44_RS08175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DVK44_RS08180	COG3958	Transketolase
DVK44_RS08185	COG3959	Transketolase, thiamine diphosphate binding domain
DVK44_RS08190	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS08200	COG0601	transmembrane transport
DVK44_RS08215	COG3507	Belongs to the glycosyl hydrolase 43 family
DVK44_RS08240	COG0583	DNA-binding transcription factor activity
DVK44_RS08255	COG3629	intracellular signal transduction
DVK44_RS08255	COG3903	Transcriptional regulator
DVK44_RS08270	COG2264	protein methyltransferase activity
DVK44_RS08300	COG4249	Peptidase C14 caspase catalytic subunit p20
DVK44_RS08300	COG2319	Wd-40 repeat
DVK44_RS08315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS08340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DVK44_RS08355	COG0789	Transcriptional regulator
DVK44_RS08380	COG1070	Carbohydrate kinase
DVK44_RS08400	COG0358	DNA primase activity
DVK44_RS08410	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DVK44_RS08430	COG0714	Associated with various cellular activities
DVK44_RS08435	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DVK44_RS08445	COG2949	membrane
DVK44_RS08470	COG1309	transcriptional regulator
DVK44_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS08490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DVK44_RS08500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DVK44_RS08500	COG2146	nitrite reductase [NAD(P)H] activity
DVK44_RS08520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DVK44_RS08520	COG0574	Belongs to the PEP-utilizing enzyme family
DVK44_RS08530	COG3842	ATPase activity
DVK44_RS08550	COG2188	Transcriptional regulator
DVK44_RS08570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DVK44_RS08580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DVK44_RS08630	COG0477	Major facilitator Superfamily
DVK44_RS08640	COG0667	Aldo Keto reductase
DVK44_RS08655	COG0423	glycine-tRNA ligase activity
DVK44_RS08660	COG0803	Belongs to the bacterial solute-binding protein 9 family
DVK44_RS08660	COG3443	Belongs to the bacterial solute-binding protein 9 family
DVK44_RS08665	COG1121	(ABC) transporter
DVK44_RS08670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DVK44_RS08680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DVK44_RS08685	COG1381	Involved in DNA repair and RecF pathway recombination
DVK44_RS08705	COG2197	response regulator
DVK44_RS08710	COG4585	Histidine kinase
DVK44_RS08715	COG2409	Drug exporters of the RND superfamily
DVK44_RS08725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DVK44_RS08755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DVK44_RS08775	COG2315	Protein conserved in bacteria
DVK44_RS08785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DVK44_RS08795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS08800	COG1234	tRNA 3'-trailer cleavage
DVK44_RS08805	COG0537	adenosine 5'-monophosphoramidase activity
DVK44_RS08820	COG0484	heat shock protein binding
DVK44_RS08825	COG1420	regulation of RNA biosynthetic process
DVK44_RS08860	COG0481	GTPase activity
DVK44_RS08865	COG0268	Binds directly to 16S ribosomal RNA
DVK44_RS08880	COG2353	YceI-like domain
DVK44_RS08885	COG1234	tRNA 3'-trailer cleavage
DVK44_RS08890	COG1555	photosystem II stabilization
DVK44_RS08895	COG1307	EDD domain protein, DegV family
DVK44_RS08905	COG0495	leucyl-tRNA aminoacylation
DVK44_RS08915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DVK44_RS08935	COG0588	phosphoglycerate mutase activity
DVK44_RS08940	COG0799	negative regulation of ribosome biogenesis
DVK44_RS08950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DVK44_RS08955	COG0501	Belongs to the peptidase M48B family
DVK44_RS08970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DVK44_RS08980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DVK44_RS08990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DVK44_RS09030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DVK44_RS09035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DVK44_RS09040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DVK44_RS09095	COG0673	inositol 2-dehydrogenase activity
DVK44_RS09100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DVK44_RS09105	COG1530	ribonuclease E activity
DVK44_RS09125	COG0772	Belongs to the SEDS family
DVK44_RS09130	COG0768	penicillin binding
DVK44_RS09145	COG1077	Cell shape determining protein MreB Mrl
DVK44_RS09150	COG0105	UTP biosynthetic process
DVK44_RS09160	COG0285	dihydrofolate synthase activity
DVK44_RS09165	COG0525	valine-tRNA ligase activity
DVK44_RS09175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DVK44_RS09180	COG0740	serine-type endopeptidase activity
DVK44_RS09185	COG0740	serine-type endopeptidase activity
DVK44_RS09190	COG0544	peptidyl-prolyl cis-trans isomerase activity
DVK44_RS09210	COG0475	glutathione-regulated potassium exporter activity
DVK44_RS09225	COG4552	Acetyltransferase involved in intracellular survival and related
DVK44_RS09240	COG0698	ribose 5-phosphate isomerase
DVK44_RS09245	COG1113	amino acid transport
DVK44_RS09255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DVK44_RS09260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DVK44_RS09290	COG2814	Major facilitator Superfamily
DVK44_RS09295	COG0583	DNA-binding transcription factor activity
DVK44_RS09310	COG1959	2 iron, 2 sulfur cluster binding
DVK44_RS09315	COG1017	nitric oxide dioxygenase activity
DVK44_RS09315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DVK44_RS09355	COG0668	transmembrane transport
DVK44_RS09360	COG1486	melibiose metabolic process
DVK44_RS09375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS09405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS09410	COG2346	COG2346, Truncated hemoglobins
DVK44_RS09450	COG0629	single-stranded DNA binding
DVK44_RS09460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DVK44_RS09470	COG0546	phosphoglycolate phosphatase activity
DVK44_RS09545	COG1131	(ABC) transporter
DVK44_RS09565	COG3833	ABC-type maltose transport systems, permease component
DVK44_RS09595	COG2197	response regulator
DVK44_RS09600	COG0475	glutathione-regulated potassium exporter activity
DVK44_RS09605	COG0367	asparagine synthase
DVK44_RS09635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS09640	COG2226	methyltransferase
DVK44_RS09640	COG3433	isochorismatase activity
DVK44_RS09640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS09650	COG3483	tryptophan 2,3-dioxygenase activity
DVK44_RS09670	COG0436	Aminotransferase
DVK44_RS09690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS09715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DVK44_RS09725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DVK44_RS09730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DVK44_RS09735	COG2124	cytochrome p450
DVK44_RS09760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DVK44_RS09785	COG2070	2-Nitropropane dioxygenase
DVK44_RS09820	COG5297	Belongs to the glycosyl hydrolase family 6
DVK44_RS09820	COG3250	beta-galactosidase activity
DVK44_RS09825	COG1764	response to oxidative stress
DVK44_RS09830	COG1846	Transcriptional regulator
DVK44_RS09835	COG3422	double-strand break repair
DVK44_RS09840	COG0367	asparagine synthase
DVK44_RS09855	COG2409	Drug exporters of the RND superfamily
DVK44_RS09860	COG1309	transcriptional regulator
DVK44_RS09875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DVK44_RS09890	COG0673	inositol 2-dehydrogenase activity
DVK44_RS09895	COG1609	Transcriptional regulator
DVK44_RS09900	COG1846	Transcriptional regulator
DVK44_RS09900	COG0456	acetyltransferase
DVK44_RS09935	COG1472	Belongs to the glycosyl hydrolase 3 family
DVK44_RS09960	COG3960	tartronate-semialdehyde synthase activity
DVK44_RS09975	COG1946	Acyl-CoA thioesterase
DVK44_RS10000	COG1309	transcriptional regulator
DVK44_RS10005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DVK44_RS10020	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS10040	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DVK44_RS10065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVK44_RS10075	COG0589	response to stress
DVK44_RS10080	COG4977	sequence-specific DNA binding
DVK44_RS10085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DVK44_RS10125	COG0745	RESPONSE REGULATOR receiver
DVK44_RS10150	COG0406	alpha-ribazole phosphatase activity
DVK44_RS10205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS10215	COG0154	amidase activity
DVK44_RS10270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DVK44_RS10310	COG0673	inositol 2-dehydrogenase activity
DVK44_RS10320	COG0706	membrane insertase activity
DVK44_RS10330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DVK44_RS10380	COG0577	efflux transmembrane transporter activity
DVK44_RS10380	COG1136	(ABC) transporter
DVK44_RS10395	COG1136	(ABC) transporter
DVK44_RS10395	COG4591	ABC-type transport system involved in lipoprotein release permease component
DVK44_RS10405	COG2733	membrane
DVK44_RS10415	COG1131	(ABC) transporter
DVK44_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DVK44_RS10435	COG2076	Multidrug Resistance protein
DVK44_RS10440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DVK44_RS10470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DVK44_RS10475	COG2409	Drug exporters of the RND superfamily
DVK44_RS10480	COG1309	transcriptional regulator
DVK44_RS10485	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DVK44_RS10490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DVK44_RS10495	COG1263	PTS System
DVK44_RS10500	COG1234	tRNA 3'-trailer cleavage
DVK44_RS10545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS10550	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DVK44_RS10560	COG1113	amino acid transport
DVK44_RS10570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DVK44_RS10580	COG1335	isochorismatase
DVK44_RS10620	COG0277	FAD linked oxidase domain protein
DVK44_RS10630	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DVK44_RS10640	COG1174	glycine betaine transport
DVK44_RS10650	COG1174	glycine betaine transport
DVK44_RS10755	COG3654	unkown
DVK44_RS10775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DVK44_RS10795	COG1678	Uncharacterized ACR, COG1678
DVK44_RS10800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DVK44_RS10805	COG0776	regulation of translation
DVK44_RS10815	COG3973	AAA domain
DVK44_RS10815	COG3973	AAA domain
DVK44_RS10840	COG2223	nitrite transmembrane transporter activity
DVK44_RS10875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS10885	COG1595	DNA-templated transcription, initiation
DVK44_RS10890	COG0346	lactoylglutathione lyase activity
DVK44_RS10920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DVK44_RS10925	COG0793	Belongs to the peptidase S41A family
DVK44_RS10935	COG2884	Cell division ATP-binding protein ftsE
DVK44_RS10950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DVK44_RS10955	COG0515	serine threonine protein kinase
DVK44_RS10960	COG0515	serine threonine protein kinase
DVK44_RS10965	COG1674	ftsk spoiiie
DVK44_RS10980	COG0395	ABC-type sugar transport system, permease component
DVK44_RS10985	COG1309	transcriptional regulator
DVK44_RS10995	COG1388	LysM domain
DVK44_RS10995	COG1134	teichoic acid transport
DVK44_RS11000	COG2902	Dehydrogenase
DVK44_RS11020	COG0653	protein targeting
DVK44_RS11030	COG3214	Protein conserved in bacteria
DVK44_RS11040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DVK44_RS11050	COG0823	Involved in the tonB-independent uptake of proteins
DVK44_RS11055	COG5002	protein histidine kinase activity
DVK44_RS11055	COG5000	phosphorelay sensor kinase activity
DVK44_RS11060	COG0745	RESPONSE REGULATOR receiver
DVK44_RS11085	COG0714	Associated with various cellular activities
DVK44_RS11130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DVK44_RS11140	COG1482	cell wall glycoprotein biosynthetic process
DVK44_RS11150	COG2835	tetraacyldisaccharide 4'-kinase activity
DVK44_RS11155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DVK44_RS11195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DVK44_RS11200	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DVK44_RS11200	COG0778	Nitroreductase
DVK44_RS11225	COG1316	TRANSCRIPTIONal
DVK44_RS11230	COG1316	TRANSCRIPTIONal
DVK44_RS11235	COG1316	TRANSCRIPTIONal
DVK44_RS11240	COG1316	TRANSCRIPTIONal
DVK44_RS11245	COG1316	TRANSCRIPTIONal
DVK44_RS11290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DVK44_RS11325	COG2205	protein histidine kinase activity
DVK44_RS11330	COG0745	RESPONSE REGULATOR receiver
DVK44_RS11335	COG3104	oligopeptide transport
DVK44_RS11345	COG1366	Belongs to the anti-sigma-factor antagonist family
DVK44_RS11350	COG1191	sigma factor activity
DVK44_RS11400	COG0667	Aldo Keto reductase
DVK44_RS11405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS11480	COG1228	amidohydrolase
DVK44_RS11495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DVK44_RS11555	COG5002	protein histidine kinase activity
DVK44_RS11575	COG1136	(ABC) transporter
DVK44_RS11580	COG0577	efflux transmembrane transporter activity
DVK44_RS11600	COG1174	glycine betaine transport
DVK44_RS11605	COG1174	glycine betaine transport
DVK44_RS11615	COG4941	Belongs to the sigma-70 factor family
DVK44_RS11625	COG0300	oxidoreductase activity
DVK44_RS11630	COG1309	transcriptional regulator
DVK44_RS11640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DVK44_RS11665	COG0802	atpase or kinase
DVK44_RS11675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DVK44_RS11685	COG0736	holo-[acyl-carrier-protein] synthase activity
DVK44_RS11690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVK44_RS11695	COG1072	(Pantothenic acid kinase))
DVK44_RS11810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DVK44_RS11815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DVK44_RS11820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DVK44_RS11825	COG0488	(ABC) transporter
DVK44_RS11835	COG0101	tRNA pseudouridine synthase activity
DVK44_RS11840	COG0203	ribosomal protein L17
DVK44_RS11845	COG0202	RNA polymerase activity
DVK44_RS11850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DVK44_RS11855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DVK44_RS11860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DVK44_RS11865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DVK44_RS11875	COG0563	adenylate kinase activity
DVK44_RS11885	COG0200	Binds to the 23S rRNA
DVK44_RS11890	COG1841	ribosomal large subunit assembly
DVK44_RS11895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DVK44_RS11900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DVK44_RS11905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DVK44_RS11910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DVK44_RS11920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DVK44_RS11925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DVK44_RS11930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DVK44_RS11935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DVK44_RS11940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DVK44_RS11945	COG0255	Belongs to the universal ribosomal protein uL29 family
DVK44_RS11950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DVK44_RS11955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DVK44_RS11960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DVK44_RS11965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DVK44_RS11970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DVK44_RS11975	COG0089	rRNA binding
DVK44_RS11980	COG0088	Forms part of the polypeptide exit tunnel
DVK44_RS11985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DVK44_RS11990	COG0051	transcription antitermination factor activity, RNA binding
DVK44_RS12000	COG0667	Aldo Keto reductase
DVK44_RS12025	COG1196	nuclear chromosome segregation
DVK44_RS12065	COG1309	transcriptional regulator
DVK44_RS12070	COG3537	Alpha-1,2-mannosidase
DVK44_RS12095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DVK44_RS12100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DVK44_RS12105	COG0049	tRNA binding
DVK44_RS12110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DVK44_RS12115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DVK44_RS12120	COG0085	RNA polymerase activity
DVK44_RS12130	COG0222	ribosome binding
DVK44_RS12135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DVK44_RS12145	COG0081	regulation of translation
DVK44_RS12150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DVK44_RS12160	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DVK44_RS12170	COG0436	Aminotransferase
DVK44_RS12175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DVK44_RS12180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DVK44_RS12190	COG2030	dehydratase
DVK44_RS12195	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DVK44_RS12210	COG0402	S-adenosylhomocysteine deaminase activity
DVK44_RS12215	COG0702	epimerase
DVK44_RS12225	COG1666	GTP binding
DVK44_RS12230	COG2261	transglycosylase associated protein
DVK44_RS12240	COG0501	Belongs to the peptidase M48B family
DVK44_RS12245	COG1007	ATP synthesis coupled electron transport
DVK44_RS12255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DVK44_RS12260	COG0713	ATP synthesis coupled electron transport
DVK44_RS12270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DVK44_RS12280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12315	COG0674	pyruvate-flavodoxin oxidoreductase activity
DVK44_RS12315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DVK44_RS12320	COG1013	pyruvate-flavodoxin oxidoreductase activity
DVK44_RS12325	COG1733	regulation of RNA biosynthetic process
DVK44_RS12330	COG0702	epimerase
DVK44_RS12345	COG1733	regulation of RNA biosynthetic process
DVK44_RS12385	COG3104	oligopeptide transport
DVK44_RS12395	COG0179	Fumarylacetoacetate (FAA) hydrolase
DVK44_RS12400	COG1007	ATP synthesis coupled electron transport
DVK44_RS12410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DVK44_RS12415	COG0713	ATP synthesis coupled electron transport
DVK44_RS12420	COG0839	Belongs to the complex I subunit 6 family
DVK44_RS12425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DVK44_RS12435	COG1034	ATP synthesis coupled electron transport
DVK44_RS12440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DVK44_RS12450	COG0649	NAD binding
DVK44_RS12455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DVK44_RS12490	COG1132	(ABC) transporter
DVK44_RS12500	COG3757	hydrolase, family 25
DVK44_RS12500	COG3409	Peptidoglycan-binding domain 1 protein
DVK44_RS12520	COG2226	methyltransferase
DVK44_RS12550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DVK44_RS12560	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DVK44_RS12585	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DVK44_RS12595	COG0163	prenyltransferase activity
DVK44_RS12605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DVK44_RS12610	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DVK44_RS12620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DVK44_RS12625	COG1333	cytochrome c biogenesis protein
DVK44_RS12630	COG0785	Cytochrome C biogenesis protein
DVK44_RS12645	COG0406	alpha-ribazole phosphatase activity
DVK44_RS12650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DVK44_RS12660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS12720	COG2255	four-way junction helicase activity
DVK44_RS12740	COG0477	Major facilitator Superfamily
DVK44_RS12810	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DVK44_RS12880	COG1690	Belongs to the RtcB family
DVK44_RS12905	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DVK44_RS12910	COG0018	arginyl-trna synthetase
DVK44_RS12920	COG2267	carboxylic ester hydrolase activity
DVK44_RS12950	COG0113	porphobilinogen synthase activity
DVK44_RS12955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DVK44_RS12955	COG1648	precorrin-2 dehydrogenase activity
DVK44_RS12960	COG0181	hydroxymethylbilane synthase activity
DVK44_RS12965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DVK44_RS12970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DVK44_RS13030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVK44_RS13055	COG0180	Tryptophanyl-tRNA synthetase
DVK44_RS13060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DVK44_RS13070	COG1129	ABC transporter
DVK44_RS13070	COG0842	Transport permease protein
DVK44_RS13075	COG2226	methyltransferase
DVK44_RS13090	COG0129	dihydroxy-acid dehydratase activity
DVK44_RS13100	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS13105	COG0248	Ppx GppA phosphatase
DVK44_RS13120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DVK44_RS13125	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DVK44_RS13135	COG0671	phosphoesterase, PA-phosphatase related
DVK44_RS13140	COG1194	a g-specific adenine glycosylase
DVK44_RS13155	COG0745	RESPONSE REGULATOR receiver
DVK44_RS13160	COG2205	protein histidine kinase activity
DVK44_RS13165	COG0477	Major facilitator Superfamily
DVK44_RS13175	COG0739	heme binding
DVK44_RS13220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DVK44_RS13240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DVK44_RS13250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DVK44_RS13255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DVK44_RS13270	COG0640	Transcriptional regulator
DVK44_RS13275	COG1660	Displays ATPase and GTPase activities
DVK44_RS13280	COG2197	response regulator
DVK44_RS13295	COG0649	NAD binding
DVK44_RS13305	COG1732	Glycine betaine
DVK44_RS13310	COG1174	glycine betaine transport
DVK44_RS13315	COG1174	glycine betaine transport
DVK44_RS13320	COG1125	glycine betaine transport
DVK44_RS13320	COG0517	IMP dehydrogenase activity
DVK44_RS13330	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DVK44_RS13330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DVK44_RS13335	COG2815	serine threonine protein kinase
DVK44_RS13335	COG0515	serine threonine protein kinase
DVK44_RS13340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DVK44_RS13350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DVK44_RS13355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DVK44_RS13365	COG0302	gtp cyclohydrolase
DVK44_RS13380	COG0037	tRNA processing
DVK44_RS13390	COG2027	D-alanyl-D-alanine carboxypeptidase
DVK44_RS13395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DVK44_RS13410	COG0789	Transcriptional regulator
DVK44_RS13420	COG0076	glutamate decarboxylase activity
DVK44_RS13440	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS13460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DVK44_RS13470	COG0254	rRNA binding
DVK44_RS13475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DVK44_RS13480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DVK44_RS13485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DVK44_RS13495	COG1289	transmembrane transporter activity
DVK44_RS13520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DVK44_RS13520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DVK44_RS13530	COG1595	DNA-templated transcription, initiation
DVK44_RS13560	COG2197	response regulator
DVK44_RS13605	COG1181	Belongs to the D-alanine--D-alanine ligase family
DVK44_RS13620	COG0500	methyltransferase
DVK44_RS13850	COG0596	Alpha beta hydrolase
DVK44_RS13855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DVK44_RS13860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DVK44_RS13865	COG1754	DNA topoisomerase type I activity
DVK44_RS13865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DVK44_RS13875	COG2890	protein-(glutamine-N5) methyltransferase activity
DVK44_RS13885	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DVK44_RS13890	COG2172	sigma factor antagonist activity
DVK44_RS13895	COG1366	Belongs to the anti-sigma-factor antagonist family
DVK44_RS13900	COG1111	helicase
DVK44_RS13900	COG1205	dead DEAH box helicase
DVK44_RS13970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DVK44_RS13975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DVK44_RS13995	COG0494	nUDIX hydrolase
DVK44_RS14010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DVK44_RS14020	COG0251	oxidation-reduction process
DVK44_RS14035	COG0003	Pfam Anion-transporting ATPase
DVK44_RS14055	COG1610	YqeY-like protein
DVK44_RS14060	COG1408	metallophosphoesterase
DVK44_RS14135	COG1215	transferase activity, transferring glycosyl groups
DVK44_RS14170	COG0326	Molecular chaperone. Has ATPase activity
DVK44_RS14215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVK44_RS14225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DVK44_RS14235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVK44_RS14260	COG1595	DNA-templated transcription, initiation
DVK44_RS14265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DVK44_RS14320	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DVK44_RS14325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DVK44_RS14340	COG0463	Glycosyl transferase, family 2
DVK44_RS14345	COG1802	Transcriptional regulator
DVK44_RS14360	COG0515	serine threonine protein kinase
DVK44_RS14360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVK44_RS14365	COG0737	Belongs to the 5'-nucleotidase family
DVK44_RS14370	COG0456	acetyltransferase
DVK44_RS14385	COG1725	Transcriptional regulator
DVK44_RS14445	COG0789	Transcriptional regulator
DVK44_RS14450	COG1280	lysine exporter protein (LysE YggA)
DVK44_RS14480	COG0306	phosphate transporter
DVK44_RS14490	COG1937	Protein conserved in bacteria
DVK44_RS14525	COG0671	phosphoesterase, PA-phosphatase related
DVK44_RS14530	COG0739	heme binding
DVK44_RS14530	COG0741	lytic transglycosylase activity
DVK44_RS14530	COG1196	nuclear chromosome segregation
DVK44_RS14590	COG1846	Transcriptional regulator
DVK44_RS14605	COG1252	NADH dehydrogenase
DVK44_RS14630	COG0579	oxidoreductase
DVK44_RS14635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DVK44_RS14680	COG0513	Belongs to the DEAD box helicase family
DVK44_RS14710	COG1643	Atp-dependent helicase
DVK44_RS14735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DVK44_RS14745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DVK44_RS14775	COG3226	Transcriptional regulator
DVK44_RS14800	COG2259	Doxx family
DVK44_RS14825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DVK44_RS14830	COG0745	RESPONSE REGULATOR receiver
DVK44_RS14835	COG2205	protein histidine kinase activity
DVK44_RS14855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS14860	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DVK44_RS14960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DVK44_RS14990	COG1289	transmembrane transporter activity
DVK44_RS15000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DVK44_RS15025	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS15030	COG1362	aminopeptidase activity
DVK44_RS15055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DVK44_RS15085	COG0477	Major facilitator Superfamily
DVK44_RS15125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVK44_RS15140	COG0653	protein targeting
DVK44_RS15160	COG0006	proline dipeptidase activity
DVK44_RS15165	COG1695	Transcriptional regulator
DVK44_RS15190	COG1999	signal sequence binding
DVK44_RS15200	COG2372	response to copper ion
DVK44_RS15215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DVK44_RS15220	COG0561	phosphatase activity
DVK44_RS15245	COG1131	(ABC) transporter
DVK44_RS15250	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DVK44_RS15265	COG0561	phosphatase activity
DVK44_RS15275	COG4988	ABC transporter
DVK44_RS15280	COG1294	oxidase, subunit
DVK44_RS15285	COG1271	oxidase subunit
DVK44_RS15290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DVK44_RS15295	COG1609	Transcriptional regulator
DVK44_RS15310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DVK44_RS15335	COG0662	Cupin 2, conserved barrel domain protein
DVK44_RS15340	COG1950	PFAM Membrane protein of
DVK44_RS15345	COG0626	cystathionine gamma-synthase activity
DVK44_RS15390	COG2132	Multicopper oxidase
DVK44_RS15400	COG0477	Major facilitator Superfamily
DVK44_RS15405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DVK44_RS15410	COG0305	Participates in initiation and elongation during chromosome replication
DVK44_RS15425	COG0359	binds to the 23S rRNA
DVK44_RS15430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DVK44_RS15435	COG0629	single-stranded DNA binding
DVK44_RS15440	COG0360	Binds together with S18 to 16S ribosomal RNA
DVK44_RS15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DVK44_RS15485	COG0617	tRNA 3'-terminal CCA addition
DVK44_RS15500	COG0515	serine threonine protein kinase
DVK44_RS15500	COG2815	serine threonine protein kinase
DVK44_RS15505	COG1595	DNA-templated transcription, initiation
DVK44_RS15515	COG0492	ferredoxin-NADP+ reductase activity
DVK44_RS15520	COG3118	belongs to the thioredoxin family
DVK44_RS15535	COG1192	Involved in chromosome partitioning
DVK44_RS15540	COG0357	Ribosomal RNA small subunit methyltransferase G
DVK44_RS15550	COG0706	membrane insertase activity
DVK44_RS15555	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DVK44_RS15565	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DVK44_RS15580	COG0592	DNA-directed DNA polymerase activity
DVK44_RS15585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DVK44_RS15590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DVK44_RS15595	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DVK44_RS15605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DVK44_RS15610	COG3266	domain, Protein
DVK44_RS15635	COG0515	serine threonine protein kinase
DVK44_RS15685	COG0596	Alpha beta hydrolase
DVK44_RS15700	COG3237	CsbD-like
DVK44_RS15710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DVK44_RS15805	COG1695	Transcriptional regulator
DVK44_RS15820	COG4585	Histidine kinase
DVK44_RS15825	COG2197	response regulator
DVK44_RS15855	COG0705	Rhomboid family
DVK44_RS15855	COG0457	Tetratricopeptide repeat
DVK44_RS15880	COG3764	Sortase (surface protein transpeptidase)
DVK44_RS15885	COG3764	Sortase (surface protein transpeptidase)
DVK44_RS15890	COG0515	serine threonine protein kinase
DVK44_RS15900	COG0768	penicillin binding
DVK44_RS15915	COG1716	ATPase activity
DVK44_RS15920	COG1716	ATPase activity
DVK44_RS15930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DVK44_RS15935	COG1733	regulation of RNA biosynthetic process
DVK44_RS15945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DVK44_RS15950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DVK44_RS15955	COG2151	metal-sulfur cluster biosynthetic enzyme
DVK44_RS15960	COG3396	Phenylacetate-CoA oxygenase
DVK44_RS15965	COG3460	Phenylacetate-CoA oxygenase
DVK44_RS15970	COG3396	Phenylacetate-CoA oxygenase
DVK44_RS15995	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVK44_RS16000	COG1309	transcriptional regulator
DVK44_RS16005	COG1522	sequence-specific DNA binding
DVK44_RS16025	COG0746	molybdenum cofactor guanylyltransferase activity
DVK44_RS16030	COG0303	'Molybdopterin
DVK44_RS16035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DVK44_RS16055	COG4591	ABC-type transport system involved in lipoprotein release permease component
DVK44_RS16055	COG1136	(ABC) transporter
DVK44_RS16070	COG0515	serine threonine protein kinase
DVK44_RS16075	COG0515	serine threonine protein kinase
DVK44_RS16100	COG0022	dehydrogenase e1 component
DVK44_RS16105	COG0508	dehydrogenase complex catalyzes the overall conversion of
DVK44_RS16130	COG1595	DNA-templated transcription, initiation
DVK44_RS16135	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS16210	COG2188	Transcriptional regulator
DVK44_RS16305	COG0745	RESPONSE REGULATOR receiver
DVK44_RS16310	COG2205	protein histidine kinase activity
DVK44_RS16320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DVK44_RS16325	COG0477	Major facilitator Superfamily
DVK44_RS16335	COG3467	pyridoxamine 5'-phosphate
DVK44_RS16340	COG2353	YceI-like domain
DVK44_RS16360	COG1191	sigma factor activity
DVK44_RS16365	COG1191	sigma factor activity
DVK44_RS16385	COG0789	Transcriptional regulator
DVK44_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS16440	COG1404	Belongs to the peptidase S8 family
DVK44_RS16465	COG1404	Belongs to the peptidase S8 family
DVK44_RS16475	COG1064	alcohol dehydrogenase
DVK44_RS16500	COG1309	transcriptional regulator
DVK44_RS16585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVK44_RS16620	COG1132	(ABC) transporter
DVK44_RS16680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DVK44_RS16680	COG4106	trans-aconitate 2-methyltransferase activity
DVK44_RS16815	COG1136	(ABC) transporter
DVK44_RS16825	COG0402	S-adenosylhomocysteine deaminase activity
DVK44_RS16845	COG0582	viral genome integration into host DNA
DVK44_RS16870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DVK44_RS16890	COG1063	alcohol dehydrogenase
DVK44_RS16920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DVK44_RS16950	COG0583	DNA-binding transcription factor activity
DVK44_RS16960	COG0431	NADPH-dependent FMN reductase
DVK44_RS16970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS17045	COG2409	Drug exporters of the RND superfamily
DVK44_RS17065	COG2197	response regulator
DVK44_RS17085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVK44_RS17125	COG0151	Belongs to the GarS family
DVK44_RS17140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DVK44_RS17150	COG2197	response regulator
DVK44_RS17165	COG1131	(ABC) transporter
DVK44_RS17185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DVK44_RS17190	COG0047	phosphoribosylformylglycinamidine synthase activity
DVK44_RS17195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DVK44_RS17245	COG2205	protein histidine kinase activity
DVK44_RS17250	COG0745	RESPONSE REGULATOR receiver
DVK44_RS17255	COG2268	Band 7 protein
DVK44_RS17270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DVK44_RS17280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DVK44_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS17360	COG0574	Belongs to the PEP-utilizing enzyme family
DVK44_RS17360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DVK44_RS17380	COG0395	ABC-type sugar transport system, permease component
DVK44_RS17385	COG1175	transmembrane transport
DVK44_RS17390	COG1940	carbohydrate kinase activity
DVK44_RS17390	COG1846	Transcriptional regulator
DVK44_RS17395	COG0662	Cupin 2, conserved barrel domain protein
DVK44_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS17410	COG1063	alcohol dehydrogenase
DVK44_RS17510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DVK44_RS17525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVK44_RS17535	COG1733	regulation of RNA biosynthetic process
DVK44_RS17545	COG3415	Transposase
DVK44_RS17545	COG2801	Transposase and inactivated derivatives
DVK44_RS17565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DVK44_RS17575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DVK44_RS17575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DVK44_RS17590	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS17680	COG1136	(ABC) transporter
DVK44_RS17685	COG0577	efflux transmembrane transporter activity
DVK44_RS17760	COG0745	RESPONSE REGULATOR receiver
DVK44_RS17765	COG5002	protein histidine kinase activity
DVK44_RS17865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS17865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS17980	COG1940	carbohydrate kinase activity
DVK44_RS17985	COG0546	phosphoglycolate phosphatase activity
DVK44_RS17990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DVK44_RS18010	COG2022	thiamine diphosphate biosynthetic process
DVK44_RS18010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DVK44_RS18085	COG0717	Belongs to the dCTP deaminase family
DVK44_RS18105	COG2181	nitrate reductase activity
DVK44_RS18105	COG0247	lactate metabolic process
DVK44_RS18110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DVK44_RS18115	COG0443	Heat shock 70 kDa protein
DVK44_RS18120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DVK44_RS18125	COG0484	heat shock protein binding
DVK44_RS18130	COG0789	Transcriptional regulator
DVK44_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS18175	COG1309	transcriptional regulator
DVK44_RS18195	COG2226	methyltransferase
DVK44_RS18260	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DVK44_RS18275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DVK44_RS18280	COG0191	fructose-bisphosphate aldolase activity
DVK44_RS18295	COG0477	Major facilitator Superfamily
DVK44_RS18315	COG3844	kynureninase activity
DVK44_RS18325	COG0596	Alpha beta hydrolase
DVK44_RS18340	COG4585	Histidine kinase
DVK44_RS18345	COG2197	response regulator
DVK44_RS18360	COG3559	Exporter of polyketide antibiotics
DVK44_RS18365	COG1131	(ABC) transporter
DVK44_RS18395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DVK44_RS18400	COG1404	Belongs to the peptidase S8 family
DVK44_RS18410	COG1404	Belongs to the peptidase S8 family
DVK44_RS18475	COG1476	TRANSCRIPTIONal
DVK44_RS18515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DVK44_RS18530	COG2409	Drug exporters of the RND superfamily
DVK44_RS18555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVK44_RS18560	COG1609	Transcriptional regulator
DVK44_RS18585	COG2897	thiosulfate sulfurtransferase activity
DVK44_RS18630	COG3485	protocatechuate 3,4-dioxygenase
DVK44_RS18635	COG0735	belongs to the Fur family
DVK44_RS18640	COG0354	folic acid binding
DVK44_RS18645	COG1490	D-aminoacyl-tRNA deacylase activity
DVK44_RS18660	COG4552	Acetyltransferase involved in intracellular survival and related
DVK44_RS18750	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS18765	COG0588	phosphoglycerate mutase activity
DVK44_RS18795	COG1329	Transcriptional regulator
DVK44_RS18800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DVK44_RS18805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DVK44_RS18815	COG0215	cysteine-tRNA ligase activity
DVK44_RS18820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DVK44_RS18840	COG3842	ATPase activity
DVK44_RS18890	COG2175	clavaminate synthase activity
DVK44_RS18905	COG0546	phosphoglycolate phosphatase activity
DVK44_RS18970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DVK44_RS19030	COG3693	PFAM glycoside hydrolase, family 10
DVK44_RS19045	COG1131	(ABC) transporter
DVK44_RS19065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DVK44_RS19160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DVK44_RS19225	COG0463	Glycosyl transferase, family 2
DVK44_RS19240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DVK44_RS19250	COG0459	protein refolding
DVK44_RS19265	COG0412	Dienelactone hydrolase
DVK44_RS19275	COG4585	Histidine kinase
DVK44_RS19280	COG2197	response regulator
DVK44_RS19320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DVK44_RS19325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DVK44_RS19370	COG3973	AAA domain
DVK44_RS19390	COG1061	Type III restriction enzyme res subunit
DVK44_RS19415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DVK44_RS19420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DVK44_RS19440	COG1120	ATPase activity
DVK44_RS19445	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS19450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS19465	COG1278	Cold shock
DVK44_RS19470	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DVK44_RS19475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DVK44_RS19485	COG2814	Major facilitator Superfamily
DVK44_RS19515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DVK44_RS19525	COG2252	PERMEase
DVK44_RS19555	COG0667	Aldo Keto reductase
DVK44_RS19560	COG2267	carboxylic ester hydrolase activity
DVK44_RS19600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DVK44_RS19625	COG2205	protein histidine kinase activity
DVK44_RS19630	COG0277	FAD linked oxidase domain protein
DVK44_RS19630	COG0247	lactate metabolic process
DVK44_RS19660	COG1595	DNA-templated transcription, initiation
DVK44_RS19665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DVK44_RS19705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS19710	COG0702	epimerase
DVK44_RS19745	COG0583	DNA-binding transcription factor activity
DVK44_RS19750	COG5006	permease, DMT superfamily
DVK44_RS19755	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS19765	COG0259	pyridoxamine-phosphate oxidase activity
DVK44_RS19775	COG0659	secondary active sulfate transmembrane transporter activity
DVK44_RS19785	COG4821	SIS domain
DVK44_RS19795	COG2945	thiolester hydrolase activity
DVK44_RS19795	COG0596	Alpha beta hydrolase
DVK44_RS19830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS19860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS19890	COG1366	Belongs to the anti-sigma-factor antagonist family
DVK44_RS19935	COG2072	flavoprotein involved in K transport
DVK44_RS19940	COG0259	pyridoxamine-phosphate oxidase activity
DVK44_RS19945	COG1309	transcriptional regulator
DVK44_RS19955	COG0515	serine threonine protein kinase
DVK44_RS19955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVK44_RS19985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DVK44_RS20025	COG1686	Belongs to the peptidase S11 family
DVK44_RS20055	COG2197	response regulator
DVK44_RS20065	COG1131	(ABC) transporter
DVK44_RS20095	COG2409	Drug exporters of the RND superfamily
DVK44_RS20115	COG0768	penicillin binding
DVK44_RS20135	COG1846	Transcriptional regulator
DVK44_RS20140	COG3384	dioxygenase
DVK44_RS20160	COG0477	Major facilitator Superfamily
DVK44_RS20170	COG1349	DNA-binding transcription factor activity
DVK44_RS20175	COG1105	Belongs to the carbohydrate kinase PfkB family
DVK44_RS20180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DVK44_RS20180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DVK44_RS20210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DVK44_RS20225	COG3263	regulation of cellular component size
DVK44_RS20235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DVK44_RS20240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DVK44_RS20250	COG0315	cyclic pyranopterin monophosphate synthase activity
DVK44_RS20255	COG0521	Mo-molybdopterin cofactor biosynthetic process
DVK44_RS20255	COG0315	cyclic pyranopterin monophosphate synthase activity
DVK44_RS20305	COG0297	glycogen (starch) synthase activity
DVK44_RS20310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DVK44_RS20330	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS20460	COG2072	flavoprotein involved in K transport
DVK44_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS20485	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DVK44_RS20490	COG4946	Tricorn protease homolog
DVK44_RS20490	COG0793	Belongs to the peptidase S41A family
DVK44_RS20500	COG2409	Drug exporters of the RND superfamily
DVK44_RS20510	COG0310	cobalt ion transport
DVK44_RS20525	COG1122	ATPase activity
DVK44_RS20535	COG0251	oxidation-reduction process
DVK44_RS20540	COG1733	regulation of RNA biosynthetic process
DVK44_RS20550	COG2197	response regulator
DVK44_RS20620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DVK44_RS20670	COG1674	ftsk spoiiie
DVK44_RS20750	COG0084	hydrolase, TatD family'
DVK44_RS20755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DVK44_RS20760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DVK44_RS20765	COG1404	Belongs to the peptidase S8 family
DVK44_RS20815	COG2409	Drug exporters of the RND superfamily
DVK44_RS20835	COG1136	(ABC) transporter
DVK44_RS20865	COG4585	Histidine kinase
DVK44_RS20875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DVK44_RS20880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DVK44_RS20885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DVK44_RS20890	COG0193	aminoacyl-tRNA hydrolase activity
DVK44_RS20900	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DVK44_RS20910	COG1309	transcriptional regulator
DVK44_RS20915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS20950	COG0604	alcohol dehydrogenase
DVK44_RS20955	COG3321	synthase
DVK44_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS20955	COG0604	alcohol dehydrogenase
DVK44_RS20965	COG4106	trans-aconitate 2-methyltransferase activity
DVK44_RS20970	COG1846	Transcriptional regulator
DVK44_RS20975	COG2197	response regulator
DVK44_RS20980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DVK44_RS21010	COG0488	(ABC) transporter
DVK44_RS21025	COG0726	polysaccharide deacetylase
DVK44_RS21130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DVK44_RS21150	COG2124	cytochrome p450
DVK44_RS21165	COG0148	phosphopyruvate hydratase activity
DVK44_RS21200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DVK44_RS21210	COG0577	efflux transmembrane transporter activity
DVK44_RS21210	COG1136	(ABC) transporter
DVK44_RS21215	COG1136	(ABC) transporter
DVK44_RS21245	COG0183	Belongs to the thiolase family
DVK44_RS21250	COG2755	lipolytic protein G-D-S-L family
DVK44_RS21265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DVK44_RS21290	COG0726	polysaccharide deacetylase
DVK44_RS21300	COG0459	protein refolding
DVK44_RS21305	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS21325	COG1595	DNA-templated transcription, initiation
DVK44_RS21335	COG0516	GMP reductase activity
DVK44_RS21345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DVK44_RS21360	COG0515	serine threonine protein kinase
DVK44_RS21365	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS21390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DVK44_RS21390	COG0519	Catalyzes the synthesis of GMP from XMP
DVK44_RS21425	COG2197	response regulator
DVK44_RS21430	COG3250	beta-galactosidase activity
DVK44_RS21460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVK44_RS21475	COG0714	Associated with various cellular activities
DVK44_RS21485	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DVK44_RS21490	COG0045	succinate-CoA ligase (ADP-forming) activity
DVK44_RS21520	COG0138	bifunctional purine biosynthesis protein purh
DVK44_RS21530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DVK44_RS21545	COG0039	L-malate dehydrogenase activity
DVK44_RS21550	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS21560	COG4175	Glycine betaine
DVK44_RS21560	COG0517	IMP dehydrogenase activity
DVK44_RS21565	COG4176	ABC-type proline glycine betaine transport system permease component
DVK44_RS21640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS21685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS21690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVK44_RS21705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS21710	COG0180	Tryptophanyl-tRNA synthetase
DVK44_RS21730	COG1295	ribonuclease BN
DVK44_RS21740	COG1408	metallophosphoesterase
DVK44_RS21745	COG1309	transcriptional regulator
DVK44_RS21790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DVK44_RS21795	COG1053	succinate dehydrogenase
DVK44_RS21805	COG2009	succinate dehydrogenase
DVK44_RS21840	COG1595	DNA-templated transcription, initiation
DVK44_RS21865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVK44_RS21880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DVK44_RS21900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS21910	COG0300	oxidoreductase activity
DVK44_RS21915	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS21955	COG0737	Belongs to the 5'-nucleotidase family
DVK44_RS22005	COG1216	Glycosyl transferase, family 2
DVK44_RS22015	COG1083	cytidylyl-transferase
DVK44_RS22020	COG2089	acid synthase
DVK44_RS22070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DVK44_RS22070	COG1473	amidohydrolase
DVK44_RS22110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVK44_RS22155	COG2814	Major facilitator Superfamily
DVK44_RS22160	COG0583	DNA-binding transcription factor activity
DVK44_RS22175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DVK44_RS22200	COG2205	protein histidine kinase activity
DVK44_RS22205	COG0745	RESPONSE REGULATOR receiver
DVK44_RS22210	COG1595	DNA-templated transcription, initiation
DVK44_RS22240	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS22285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DVK44_RS22305	COG1349	DNA-binding transcription factor activity
DVK44_RS22315	COG4770	biotin carboxylase activity
DVK44_RS22320	COG0424	maF-like protein
DVK44_RS22325	COG2205	protein histidine kinase activity
DVK44_RS22330	COG0745	RESPONSE REGULATOR receiver
DVK44_RS22350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DVK44_RS22365	COG1024	Enoyl-CoA hydratase
DVK44_RS22375	COG2986	histidine ammonia-lyase
DVK44_RS22395	COG1376	ErfK ybiS ycfS ynhG family protein
DVK44_RS22405	COG1136	(ABC) transporter
DVK44_RS22430	COG0488	(ABC) transporter
DVK44_RS22460	COG1940	carbohydrate kinase activity
DVK44_RS22470	COG1175	transmembrane transport
DVK44_RS22475	COG0395	ABC-type sugar transport system, permease component
DVK44_RS22505	COG1619	proteins homologs of microcin C7 resistance protein MccF
DVK44_RS22510	COG1404	Belongs to the peptidase S8 family
DVK44_RS22525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DVK44_RS22555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DVK44_RS22560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DVK44_RS22570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVK44_RS22625	COG1331	Highly conserved protein containing a thioredoxin domain
DVK44_RS22640	COG0463	Glycosyl transferase, family 2
DVK44_RS22705	COG0367	asparagine synthase
DVK44_RS22710	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS22715	COG1309	transcriptional regulator
DVK44_RS22720	COG0477	Major facilitator Superfamily
DVK44_RS22730	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DVK44_RS22740	COG0436	Aminotransferase
DVK44_RS22770	COG1414	Transcriptional regulator
DVK44_RS22805	COG2894	cell division
DVK44_RS22840	COG2197	response regulator
DVK44_RS22860	COG2885	chlorophyll binding
DVK44_RS22885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DVK44_RS22890	COG2226	methyltransferase
DVK44_RS22895	COG0667	Aldo Keto reductase
DVK44_RS22900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DVK44_RS22905	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DVK44_RS22925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS22930	COG0450	alkyl hydroperoxide reductase
DVK44_RS22940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DVK44_RS22940	COG4499	WXG100 protein secretion system (Wss), protein YukC
DVK44_RS22960	COG0114	fumarate hydratase activity
DVK44_RS22965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DVK44_RS22965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DVK44_RS22990	COG0778	Nitroreductase
DVK44_RS22995	COG1722	exodeoxyribonuclease VII activity
DVK44_RS23000	COG1570	exodeoxyribonuclease VII activity
DVK44_RS23005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DVK44_RS23020	COG0012	GTP binding
DVK44_RS23030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DVK44_RS23035	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DVK44_RS23040	COG1984	allophanate hydrolase subunit 2
DVK44_RS23070	COG1842	Phage shock protein A
DVK44_RS23115	COG4166	transmembrane transport
DVK44_RS23125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS23135	COG4608	Belongs to the ABC transporter superfamily
DVK44_RS23145	COG0601	transmembrane transport
DVK44_RS23150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS23160	COG4608	Belongs to the ABC transporter superfamily
DVK44_RS23170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DVK44_RS23215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS23220	COG1611	Belongs to the LOG family
DVK44_RS23225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DVK44_RS23240	COG0519	Catalyzes the synthesis of GMP from XMP
DVK44_RS23245	COG1024	Enoyl-CoA hydratase
DVK44_RS23260	COG1595	DNA-templated transcription, initiation
DVK44_RS23270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DVK44_RS23275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DVK44_RS23330	COG0598	Magnesium transport protein CorA
DVK44_RS23350	COG2095	MarC family integral membrane protein
DVK44_RS23355	COG1432	Conserved Protein
DVK44_RS23365	COG0513	Belongs to the DEAD box helicase family
DVK44_RS23420	COG4172	Belongs to the ABC transporter superfamily
DVK44_RS23425	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS23480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS23515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DVK44_RS23570	COG3480	Lon protease (S16) C-terminal proteolytic domain
DVK44_RS23580	COG1615	UPF0182 protein
DVK44_RS23610	COG0483	inositol monophosphate 1-phosphatase activity
DVK44_RS23630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DVK44_RS23640	COG2135	peptidase activity
DVK44_RS23650	COG1595	DNA-templated transcription, initiation
DVK44_RS23675	COG0242	peptide deformylase activity
DVK44_RS23685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DVK44_RS23700	COG0535	radical SAM domain protein
DVK44_RS23745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DVK44_RS23765	COG1966	Carbon starvation protein
DVK44_RS23780	COG2182	Extracellular solute-binding protein
DVK44_RS23785	COG1175	transmembrane transport
DVK44_RS23790	COG0395	ABC-type sugar transport system, permease component
DVK44_RS23795	COG1472	Belongs to the glycosyl hydrolase 3 family
DVK44_RS23800	COG0363	glucosamine-6-phosphate deaminase activity
DVK44_RS23805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVK44_RS23820	COG1597	lipid kinase activity
DVK44_RS23835	COG2172	sigma factor antagonist activity
DVK44_RS23850	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DVK44_RS23855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVK44_RS23865	COG0456	acetyltransferase
DVK44_RS23890	COG0477	Major facilitator Superfamily
DVK44_RS23930	COG4106	trans-aconitate 2-methyltransferase activity
DVK44_RS23935	COG1126	abc transporter atp-binding protein
DVK44_RS23950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS23960	COG0281	malic enzyme
DVK44_RS23970	COG3540	Alkaline phosphatase
DVK44_RS23975	COG0604	alcohol dehydrogenase
DVK44_RS23990	COG0326	Molecular chaperone. Has ATPase activity
DVK44_RS24030	COG2255	four-way junction helicase activity
DVK44_RS24070	COG0508	dehydrogenase complex catalyzes the overall conversion of
DVK44_RS24070	COG0567	Dehydrogenase, E1 component
DVK44_RS24075	COG2205	protein histidine kinase activity
DVK44_RS24080	COG0745	RESPONSE REGULATOR receiver
DVK44_RS24100	COG1131	(ABC) transporter
DVK44_RS24110	COG1595	DNA-templated transcription, initiation
DVK44_RS24120	COG1929	Belongs to the glycerate kinase type-1 family
DVK44_RS24125	COG1620	l-lactate permease
DVK44_RS24140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DVK44_RS24185	COG0791	NLP P60 protein
DVK44_RS24185	COG3883	PFAM NLP P60 protein
DVK44_RS24200	COG2045	Belongs to the ComB family
DVK44_RS24215	COG1917	Cupin 2, conserved barrel domain protein
DVK44_RS24255	COG0596	Alpha beta hydrolase
DVK44_RS24270	COG0154	amidase activity
DVK44_RS24275	COG0768	penicillin binding
DVK44_RS24290	COG2205	protein histidine kinase activity
DVK44_RS24310	COG3285	dna ligase
DVK44_RS24310	COG1793	dna ligase
DVK44_RS24315	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DVK44_RS24335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS24340	COG1120	ATPase activity
DVK44_RS24350	COG0747	negative chemotaxis
DVK44_RS24375	COG1309	transcriptional regulator
DVK44_RS24400	COG0018	arginyl-trna synthetase
DVK44_RS24405	COG0019	diaminopimelate decarboxylase activity
DVK44_RS24410	COG0460	homoserine dehydrogenase
DVK44_RS24415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DVK44_RS24420	COG0083	homoserine kinase activity
DVK44_RS24430	COG1316	TRANSCRIPTIONal
DVK44_RS24435	COG0254	rRNA binding
DVK44_RS24440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DVK44_RS24445	COG2890	protein-(glutamine-N5) methyltransferase activity
DVK44_RS24455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DVK44_RS24490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DVK44_RS24510	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DVK44_RS24515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DVK44_RS24520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DVK44_RS24525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DVK44_RS24530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DVK44_RS24535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DVK44_RS24540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DVK44_RS24555	COG2197	response regulator
DVK44_RS24560	COG4585	Histidine kinase
DVK44_RS24570	COG0738	Major facilitator superfamily
DVK44_RS24575	COG1609	Transcriptional regulator
DVK44_RS24585	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVK44_RS24600	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DVK44_RS24655	COG0183	Belongs to the thiolase family
DVK44_RS24745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVK44_RS24745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVK44_RS24760	COG0842	Transport permease protein
DVK44_RS24800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DVK44_RS24805	COG0280	phosphate acetyltransferase
DVK44_RS24805	COG0857	belongs to the CobB CobQ family
DVK44_RS24810	COG0205	6-phosphofructokinase activity
DVK44_RS24820	COG4565	transcriptional regulatory protein
DVK44_RS24825	COG3290	protein histidine kinase activity
DVK44_RS24830	COG1301	dicarboxylic acid transport
DVK44_RS24840	COG2124	cytochrome p450
DVK44_RS24860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DVK44_RS24905	COG1404	Belongs to the peptidase S8 family
DVK44_RS24945	COG1090	epimerase
DVK44_RS24950	COG1595	DNA-templated transcription, initiation
DVK44_RS24965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS24985	COG3118	belongs to the thioredoxin family
DVK44_RS24990	COG1349	DNA-binding transcription factor activity
DVK44_RS25000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DVK44_RS25020	COG0477	Major facilitator Superfamily
DVK44_RS25030	COG1802	Transcriptional regulator
DVK44_RS25045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DVK44_RS25050	COG3281	Trehalose synthase
DVK44_RS25055	COG0366	Alpha amylase catalytic
DVK44_RS25060	COG0366	Alpha amylase catalytic
DVK44_RS25065	COG0058	SHG alpha-glucan phosphorylase activity
DVK44_RS25090	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS25105	COG1132	(ABC) transporter
DVK44_RS25110	COG1132	(ABC) transporter
DVK44_RS25115	COG1131	(ABC) transporter
DVK44_RS25125	COG4585	Histidine kinase
DVK44_RS25130	COG2197	response regulator
DVK44_RS25140	COG1376	ErfK ybiS ycfS ynhG family protein
DVK44_RS25150	COG1024	Enoyl-CoA hydratase
DVK44_RS25160	COG0726	polysaccharide deacetylase
DVK44_RS25175	COG1120	ATPase activity
DVK44_RS25180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS25220	COG0444	Belongs to the ABC transporter superfamily
DVK44_RS25225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS25230	COG0601	transmembrane transport
DVK44_RS25240	COG0561	phosphatase activity
DVK44_RS25245	COG1609	Transcriptional regulator
DVK44_RS25260	COG0395	ABC-type sugar transport system, permease component
DVK44_RS25275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS25280	COG1760	l-serine dehydratase
DVK44_RS25285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DVK44_RS25290	COG0509	glycine decarboxylation via glycine cleavage system
DVK44_RS25295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DVK44_RS25320	COG0747	negative chemotaxis
DVK44_RS25325	COG0601	transmembrane transport
DVK44_RS25330	COG0444	Belongs to the ABC transporter superfamily
DVK44_RS25335	COG4608	Belongs to the ABC transporter superfamily
DVK44_RS25340	COG2860	membrane
DVK44_RS25360	COG0482	sulfurtransferase activity
DVK44_RS25380	COG0583	DNA-binding transcription factor activity
DVK44_RS25435	COG1611	Belongs to the LOG family
DVK44_RS25450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DVK44_RS25460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DVK44_RS25465	COG0154	amidase activity
DVK44_RS25485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DVK44_RS25505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DVK44_RS25520	COG2197	response regulator
DVK44_RS25530	COG2133	pyrroloquinoline quinone binding
DVK44_RS25535	COG0667	Aldo Keto reductase
DVK44_RS25555	COG0440	acetolactate synthase activity
DVK44_RS25560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DVK44_RS25565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DVK44_RS25580	COG3835	regulator
DVK44_RS25585	COG0506	proline dehydrogenase activity
DVK44_RS25590	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS25605	COG0473	3-isopropylmalate dehydrogenase activity
DVK44_RS25610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DVK44_RS25615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DVK44_RS25625	COG2353	YceI-like domain
DVK44_RS25645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DVK44_RS25665	COG2018	Roadblock/LC7 domain
DVK44_RS25685	COG2018	Roadblock/LC7 domain
DVK44_RS25690	COG5002	protein histidine kinase activity
DVK44_RS25695	COG0179	Fumarylacetoacetate (FAA) hydrolase
DVK44_RS25700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DVK44_RS25730	COG1414	Transcriptional regulator
DVK44_RS25735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DVK44_RS25740	COG0066	3-isopropylmalate dehydratase activity
DVK44_RS25750	COG0776	regulation of translation
DVK44_RS25760	COG1920	GTP binding
DVK44_RS25770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DVK44_RS25775	COG1181	Belongs to the D-alanine--D-alanine ligase family
DVK44_RS25795	COG0351	phosphomethylpyrimidine kinase
DVK44_RS25800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DVK44_RS25805	COG1461	Dihydroxyacetone kinase
DVK44_RS25815	COG0742	ribosomal rna small subunit methyltransferase
DVK44_RS25820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DVK44_RS25835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DVK44_RS25840	COG0571	ribonuclease III activity
DVK44_RS25845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DVK44_RS25850	COG1733	regulation of RNA biosynthetic process
DVK44_RS25855	COG2340	Cysteine-rich secretory protein family
DVK44_RS25860	COG1254	Belongs to the acylphosphatase family
DVK44_RS25875	COG0477	Major facilitator Superfamily
DVK44_RS25905	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DVK44_RS25925	COG0228	four-way junction DNA binding
DVK44_RS25930	COG1837	Belongs to the UPF0109 family
DVK44_RS25935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DVK44_RS25940	COG0336	Belongs to the RNA methyltransferase TrmD family
DVK44_RS25945	COG0335	large ribosomal subunit rRNA binding
DVK44_RS25950	COG0681	Belongs to the peptidase S26 family
DVK44_RS25965	COG0681	Belongs to the peptidase S26 family
DVK44_RS25970	COG0494	nUDIX hydrolase
DVK44_RS25980	COG0792	nuclease activity
DVK44_RS25995	COG1191	sigma factor activity
DVK44_RS26010	COG0052	Belongs to the universal ribosomal protein uS2 family
DVK44_RS26015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DVK44_RS26020	COG0528	UMP kinase activity
DVK44_RS26025	COG0233	cytoplasmic translational termination
DVK44_RS26035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DVK44_RS26050	COG3842	ATPase activity
DVK44_RS26060	COG1136	(ABC) transporter
DVK44_RS26065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DVK44_RS26075	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS26090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DVK44_RS26120	COG3842	ATPase activity
DVK44_RS26125	COG1176	ABC-type spermidine putrescine transport system, permease component I
DVK44_RS26130	COG1177	transmembrane transport
DVK44_RS26135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DVK44_RS26160	COG2508	Transcriptional regulator
DVK44_RS26180	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS26205	COG0750	zinc metalloprotease
DVK44_RS26210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DVK44_RS26225	COG0442	prolyl-tRNA aminoacylation
DVK44_RS26245	COG0779	Required for maturation of 30S ribosomal subunits
DVK44_RS26260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DVK44_RS26270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DVK44_RS26275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DVK44_RS26295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS26300	COG0601	transmembrane transport
DVK44_RS26310	COG0455	bacterial-type flagellum organization
DVK44_RS26330	COG3266	domain, Protein
DVK44_RS26335	COG1404	Belongs to the peptidase S8 family
DVK44_RS26375	COG1674	ftsk spoiiie
DVK44_RS26385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DVK44_RS26390	COG1185	polyribonucleotide nucleotidyltransferase activity
DVK44_RS26395	COG0612	Peptidase, M16
DVK44_RS26400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DVK44_RS26420	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DVK44_RS26425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DVK44_RS26430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DVK44_RS26460	COG2208	phosphoserine phosphatase activity
DVK44_RS26460	COG2770	Histidine kinase
DVK44_RS26465	COG2205	protein histidine kinase activity
DVK44_RS26465	COG3437	response regulator, receiver
DVK44_RS26465	COG4999	Histidine kinase
DVK44_RS26465	COG3850	Histidine kinase
DVK44_RS26475	COG1674	ftsk spoiiie
DVK44_RS26485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DVK44_RS26495	COG1058	Belongs to the CinA family
DVK44_RS26495	COG1546	Belongs to the CinA family
DVK44_RS26500	COG1396	sequence-specific DNA binding
DVK44_RS26505	COG0783	Belongs to the Dps family
DVK44_RS26515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DVK44_RS26520	COG1201	RNA secondary structure unwinding
DVK44_RS26525	COG1917	Cupin 2, conserved barrel domain protein
DVK44_RS26525	COG2207	Transcriptional regulator
DVK44_RS26555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DVK44_RS26575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS26580	COG0765	amino acid transport
DVK44_RS26585	COG0765	amino acid transport
DVK44_RS26590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS26595	COG1126	abc transporter atp-binding protein
DVK44_RS26600	COG0745	RESPONSE REGULATOR receiver
DVK44_RS26605	COG2205	protein histidine kinase activity
DVK44_RS26615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DVK44_RS26630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DVK44_RS26640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DVK44_RS26645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DVK44_RS26655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DVK44_RS26695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DVK44_RS26700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DVK44_RS26725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DVK44_RS26760	COG2186	Transcriptional regulator
DVK44_RS26765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DVK44_RS26780	COG0187	DNA topoisomerase II activity
DVK44_RS26790	COG4585	Histidine kinase
DVK44_RS26795	COG2197	response regulator
DVK44_RS26805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DVK44_RS26810	COG4565	transcriptional regulatory protein
DVK44_RS26815	COG3290	protein histidine kinase activity
DVK44_RS26820	COG0372	Belongs to the citrate synthase family
DVK44_RS26825	COG0372	Belongs to the citrate synthase family
DVK44_RS26830	COG0523	cobalamin synthesis protein
DVK44_RS26835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DVK44_RS26840	COG0612	Peptidase, M16
DVK44_RS26855	COG1802	Transcriptional regulator
DVK44_RS26865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DVK44_RS26885	COG1435	thymidine kinase activity
DVK44_RS26930	COG0745	RESPONSE REGULATOR receiver
DVK44_RS26935	COG2205	protein histidine kinase activity
DVK44_RS26960	COG0756	dUTP diphosphatase activity
DVK44_RS26975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DVK44_RS26980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DVK44_RS26985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DVK44_RS27015	COG0569	domain protein
DVK44_RS27020	COG0531	amino acid
DVK44_RS27025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DVK44_RS27040	COG4974	Belongs to the 'phage' integrase family
DVK44_RS27070	COG2910	NAD(P)H-binding
DVK44_RS27075	COG1733	regulation of RNA biosynthetic process
DVK44_RS27120	COG3293	Transposase
DVK44_RS27140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DVK44_RS27270	COG0714	Associated with various cellular activities
DVK44_RS27400	COG0151	Belongs to the GarS family
DVK44_RS27430	COG0798	PFAM Bile acid sodium symporter
DVK44_RS27435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DVK44_RS27450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DVK44_RS27455	COG0573	inorganic phosphate transmembrane transporter activity
DVK44_RS27460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DVK44_RS27485	COG0243	molybdopterin cofactor binding
DVK44_RS27490	COG0640	Transcriptional regulator
DVK44_RS27495	COG2197	response regulator
DVK44_RS27500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DVK44_RS27505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DVK44_RS27510	COG0504	CTP synthase activity
DVK44_RS27530	COG0439	Biotin carboxylase
DVK44_RS27545	COG1181	Belongs to the D-alanine--D-alanine ligase family
DVK44_RS27550	COG1132	(ABC) transporter
DVK44_RS27555	COG1132	(ABC) transporter
DVK44_RS27590	COG0640	Transcriptional regulator
DVK44_RS27665	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS27700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DVK44_RS27710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DVK44_RS27720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DVK44_RS27730	COG0302	gtp cyclohydrolase
DVK44_RS27735	COG0602	queuosine metabolic process
DVK44_RS27795	COG3387	PFAM Glycoside hydrolase 15-related
DVK44_RS27830	COG1324	tolerance protein
DVK44_RS27880	COG2801	Transposase and inactivated derivatives
DVK44_RS27880	COG3415	Transposase
DVK44_RS27890	COG1733	regulation of RNA biosynthetic process
DVK44_RS27900	COG0583	DNA-binding transcription factor activity
DVK44_RS27910	COG1063	alcohol dehydrogenase
DVK44_RS27930	COG4585	Histidine kinase
DVK44_RS27935	COG2197	response regulator
DVK44_RS27960	COG3835	regulator
DVK44_RS27970	COG0765	amino acid transport
DVK44_RS27975	COG0765	amino acid transport
DVK44_RS27990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS27995	COG3473	Maleate cis-trans isomerase
DVK44_RS28005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DVK44_RS28015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DVK44_RS28050	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS28055	COG0673	inositol 2-dehydrogenase activity
DVK44_RS28060	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS28070	COG3962	Belongs to the TPP enzyme family
DVK44_RS28075	COG3718	enzyme involved in inositol metabolism
DVK44_RS28085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS28090	COG1609	Transcriptional regulator
DVK44_RS28125	COG0395	ABC-type sugar transport system, permease component
DVK44_RS28130	COG1175	transmembrane transport
DVK44_RS28150	COG1799	cell septum assembly
DVK44_RS28175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DVK44_RS28185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DVK44_RS28205	COG1404	Belongs to the peptidase S8 family
DVK44_RS28220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS28230	COG0477	Major facilitator Superfamily
DVK44_RS28240	COG0667	Aldo Keto reductase
DVK44_RS28270	COG0667	Aldo Keto reductase
DVK44_RS28275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS28280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS28295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS28310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DVK44_RS28315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DVK44_RS28335	COG1653	transport
DVK44_RS28340	COG1175	transmembrane transport
DVK44_RS28345	COG0395	ABC-type sugar transport system, permease component
DVK44_RS28350	COG1940	carbohydrate kinase activity
DVK44_RS28355	COG4213	ABC transporter substrate-binding protein
DVK44_RS28365	COG4214	carbohydrate transport
DVK44_RS28370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DVK44_RS28375	COG0531	amino acid
DVK44_RS28390	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVK44_RS28390	COG1024	Enoyl-CoA hydratase
DVK44_RS28395	COG0183	Belongs to the thiolase family
DVK44_RS28415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DVK44_RS28420	COG0446	pyridine nucleotide-disulphide oxidoreductase
DVK44_RS28460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DVK44_RS28465	COG1120	ATPase activity
DVK44_RS28480	COG3220	belongs to the UPF0276 family
DVK44_RS28500	COG2409	Drug exporters of the RND superfamily
DVK44_RS28505	COG0477	Major facilitator Superfamily
DVK44_RS28510	COG1846	Transcriptional regulator
DVK44_RS28520	COG1116	anion transmembrane transporter activity
DVK44_RS28540	COG2326	polyphosphate kinase activity
DVK44_RS28575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DVK44_RS28580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DVK44_RS28590	COG0346	lactoylglutathione lyase activity
DVK44_RS28605	COG0667	Aldo Keto reductase
DVK44_RS28665	COG1119	ATPase activity
DVK44_RS28670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DVK44_RS28685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DVK44_RS28690	COG1116	anion transmembrane transporter activity
DVK44_RS28710	COG0529	Catalyzes the synthesis of activated sulfate
DVK44_RS28715	COG0175	sulfate reduction
DVK44_RS28740	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS28750	COG0456	acetyltransferase
DVK44_RS28750	COG1846	Transcriptional regulator
DVK44_RS28760	COG1404	Belongs to the peptidase S8 family
DVK44_RS28785	COG0110	maltose O-acetyltransferase activity
DVK44_RS28815	COG0366	Alpha amylase catalytic
DVK44_RS28820	COG3152	Membrane
DVK44_RS28850	COG2755	lipolytic protein G-D-S-L family
DVK44_RS28855	COG1522	sequence-specific DNA binding
DVK44_RS28875	COG1595	DNA-templated transcription, initiation
DVK44_RS28895	COG1162	GTPase activity
DVK44_RS28925	COG0028	Belongs to the TPP enzyme family
DVK44_RS28945	COG1802	Transcriptional regulator
DVK44_RS28950	COG1024	Enoyl-CoA hydratase
DVK44_RS28955	COG2124	cytochrome p450
DVK44_RS28985	COG1132	(ABC) transporter
DVK44_RS28990	COG1132	(ABC) transporter
DVK44_RS29015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DVK44_RS29020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DVK44_RS29020	COG3608	succinylglutamate desuccinylase aspartoacylase
DVK44_RS29045	COG1162	GTPase activity
DVK44_RS29095	COG1414	Transcriptional regulator
DVK44_RS29100	COG2146	nitrite reductase [NAD(P)H] activity
DVK44_RS29125	COG2351	hydroxyisourate hydrolase activity
DVK44_RS29145	COG1396	sequence-specific DNA binding
DVK44_RS29155	COG1819	glycosyl
DVK44_RS29160	COG0789	Transcriptional regulator
DVK44_RS29180	COG1414	Transcriptional regulator
DVK44_RS29185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DVK44_RS29190	COG4266	Belongs to the allantoicase family
DVK44_RS29200	COG2197	response regulator
DVK44_RS29210	COG2188	Transcriptional regulator
DVK44_RS29230	COG1940	carbohydrate kinase activity
DVK44_RS29240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS29245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DVK44_RS29275	COG1126	abc transporter atp-binding protein
DVK44_RS29280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS29285	COG0765	amino acid transport
DVK44_RS29290	COG0765	amino acid transport
DVK44_RS29300	COG0405	Gamma-glutamyltransferase
DVK44_RS29305	COG3250	beta-galactosidase activity
DVK44_RS29335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS29340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DVK44_RS29355	COG2205	protein histidine kinase activity
DVK44_RS29360	COG0745	RESPONSE REGULATOR receiver
DVK44_RS29365	COG2409	Drug exporters of the RND superfamily
DVK44_RS29370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DVK44_RS29375	COG0371	Dehydrogenase
DVK44_RS29565	COG0791	NLP P60 protein
DVK44_RS29670	COG0483	inositol monophosphate 1-phosphatase activity
DVK44_RS29715	COG1929	Belongs to the glycerate kinase type-1 family
DVK44_RS29725	COG0688	phosphatidylethanolamine metabolic process
DVK44_RS29730	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS29740	COG2301	Belongs to the HpcH HpaI aldolase family
DVK44_RS29745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVK44_RS29745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DVK44_RS29750	COG0604	alcohol dehydrogenase
DVK44_RS29810	COG2362	D-Aminopeptidase
DVK44_RS29815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DVK44_RS29820	COG0823	Involved in the tonB-independent uptake of proteins
DVK44_RS29820	COG1506	peptidase
DVK44_RS29820	COG4946	Tricorn protease homolog
DVK44_RS29825	COG1619	proteins homologs of microcin C7 resistance protein MccF
DVK44_RS29830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DVK44_RS29850	COG2226	methyltransferase
DVK44_RS29865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DVK44_RS29905	COG1609	Transcriptional regulator
DVK44_RS29915	COG1175	transmembrane transport
DVK44_RS29920	COG0395	ABC-type sugar transport system, permease component
DVK44_RS29935	COG1191	sigma factor activity
DVK44_RS29940	COG2154	pterin-4-alpha-carbinolamine dehydratase
DVK44_RS29945	COG0656	L-ascorbic acid biosynthetic process
DVK44_RS29960	COG2239	Acts as a magnesium transporter
DVK44_RS29975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DVK44_RS29980	COG1131	(ABC) transporter
DVK44_RS30000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVK44_RS30005	COG1940	carbohydrate kinase activity
DVK44_RS30010	COG1129	ABC transporter
DVK44_RS30015	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS30025	COG0673	inositol 2-dehydrogenase activity
DVK44_RS30045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DVK44_RS30105	COG1846	Transcriptional regulator
DVK44_RS30110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DVK44_RS30110	COG1017	nitric oxide dioxygenase activity
DVK44_RS30175	COG1793	dna ligase
DVK44_RS30215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DVK44_RS30220	COG1349	DNA-binding transcription factor activity
DVK44_RS30240	COG0667	Aldo Keto reductase
DVK44_RS30250	COG0395	ABC-type sugar transport system, permease component
DVK44_RS30255	COG1175	transmembrane transport
DVK44_RS30270	COG0179	Fumarylacetoacetate (FAA) hydrolase
DVK44_RS30280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DVK44_RS30330	COG0515	serine threonine protein kinase
DVK44_RS30335	COG0515	serine threonine protein kinase
DVK44_RS30335	COG2815	serine threonine protein kinase
DVK44_RS30405	COG1357	PFAM Pentapeptide repeats (8 copies)
DVK44_RS30410	COG1686	Belongs to the peptidase S11 family
DVK44_RS30505	COG1349	DNA-binding transcription factor activity
DVK44_RS30515	COG2182	Extracellular solute-binding protein
DVK44_RS30525	COG0395	ABC-type sugar transport system, permease component
DVK44_RS30530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS30535	COG1486	melibiose metabolic process
DVK44_RS30540	COG1070	Carbohydrate kinase
DVK44_RS30550	COG1940	carbohydrate kinase activity
DVK44_RS30585	COG4214	carbohydrate transport
DVK44_RS30615	COG1414	Transcriptional regulator
DVK44_RS30620	COG3012	SEC-C Motif Domain Protein
DVK44_RS30630	COG1793	dna ligase
DVK44_RS30660	COG1515	deoxyribonuclease V activity
DVK44_RS30675	COG0488	(ABC) transporter
DVK44_RS30680	COG1834	amidinotransferase
DVK44_RS30700	COG3268	Saccharopine dehydrogenase
DVK44_RS30705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DVK44_RS30710	COG0183	Belongs to the thiolase family
DVK44_RS30715	COG1250	3-hydroxyacyl-CoA dehydrogenase
DVK44_RS30715	COG1024	Enoyl-CoA hydratase
DVK44_RS30720	COG1309	transcriptional regulator
DVK44_RS30730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DVK44_RS30735	COG0477	Major facilitator Superfamily
DVK44_RS30745	COG2936	dipeptidyl-peptidase activity
DVK44_RS30760	COG0488	(ABC) transporter
DVK44_RS30765	COG2183	response to ionizing radiation
DVK44_RS30775	COG1024	Enoyl-CoA hydratase
DVK44_RS30785	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DVK44_RS30810	COG0371	Dehydrogenase
DVK44_RS30830	COG1388	LysM domain
DVK44_RS30830	COG1134	teichoic acid transport
DVK44_RS30835	COG1562	ergosterol biosynthetic process
DVK44_RS30845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DVK44_RS30855	COG1657	PFAM Prenyltransferase squalene oxidase
DVK44_RS30895	COG2755	lipolytic protein G-D-S-L family
DVK44_RS30905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DVK44_RS30925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS30955	COG0500	methyltransferase
DVK44_RS30965	COG0604	alcohol dehydrogenase
DVK44_RS30965	COG3321	synthase
DVK44_RS30970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS30975	COG0156	8-amino-7-oxononanoate synthase activity
DVK44_RS30980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS30985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS30990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DVK44_RS30995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS31000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DVK44_RS31005	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DVK44_RS31035	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS31045	COG3629	intracellular signal transduction
DVK44_RS31090	COG3958	Transketolase
DVK44_RS31095	COG3959	Transketolase, thiamine diphosphate binding domain
DVK44_RS31105	COG1404	Belongs to the peptidase S8 family
DVK44_RS31115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DVK44_RS31140	COG3842	ATPase activity
DVK44_RS31170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DVK44_RS31175	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS31190	COG0247	lactate metabolic process
DVK44_RS31195	COG1139	Iron-sulfur cluster binding protein
DVK44_RS31200	COG1556	Lactate utilization protein
DVK44_RS31220	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS31245	COG0477	Major facilitator Superfamily
DVK44_RS31265	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31280	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31295	COG1063	alcohol dehydrogenase
DVK44_RS31300	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS31305	COG0022	dehydrogenase e1 component
DVK44_RS31310	COG1309	transcriptional regulator
DVK44_RS31320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS31325	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31345	COG0366	Alpha amylase catalytic
DVK44_RS31380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DVK44_RS31390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DVK44_RS31400	COG0586	Pfam SNARE associated Golgi protein
DVK44_RS31410	COG1131	(ABC) transporter
DVK44_RS31415	COG4585	Histidine kinase
DVK44_RS31420	COG2197	response regulator
DVK44_RS31435	COG0252	asparaginase activity
DVK44_RS31450	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31455	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31465	COG1609	Transcriptional regulator
DVK44_RS31475	COG1175	transmembrane transport
DVK44_RS31480	COG0395	ABC-type sugar transport system, permease component
DVK44_RS31485	COG1501	Belongs to the glycosyl hydrolase 31 family
DVK44_RS31505	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DVK44_RS31510	COG1349	DNA-binding transcription factor activity
DVK44_RS31530	COG1063	alcohol dehydrogenase
DVK44_RS31540	COG1652	LysM domain
DVK44_RS31555	COG0456	acetyltransferase
DVK44_RS31590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DVK44_RS31600	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS31605	COG1063	alcohol dehydrogenase
DVK44_RS31610	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS31615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DVK44_RS31625	COG1414	Transcriptional regulator
DVK44_RS31650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DVK44_RS31655	COG3275	phosphorelay sensor kinase activity
DVK44_RS31685	COG0726	polysaccharide deacetylase
DVK44_RS31730	COG0583	DNA-binding transcription factor activity
DVK44_RS31740	COG1053	succinate dehydrogenase
DVK44_RS31745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DVK44_RS31750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS31755	COG3360	Dodecin
DVK44_RS31770	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DVK44_RS31775	COG0121	glutamine amidotransferase
DVK44_RS31780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DVK44_RS31805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DVK44_RS31830	COG1802	Transcriptional regulator
DVK44_RS31845	COG2084	Dehydrogenase
DVK44_RS31850	COG2610	gluconate transmembrane transporter activity
DVK44_RS31855	COG3250	beta-galactosidase activity
DVK44_RS31865	COG1316	TRANSCRIPTIONal
DVK44_RS31890	COG0531	amino acid
DVK44_RS31900	COG1126	abc transporter atp-binding protein
DVK44_RS31915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS31945	COG4585	Histidine kinase
DVK44_RS31950	COG2409	Drug exporters of the RND superfamily
DVK44_RS31990	COG1609	Transcriptional regulator
DVK44_RS31995	COG2211	Major facilitator Superfamily
DVK44_RS32010	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS32015	COG0667	Aldo Keto reductase
DVK44_RS32050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DVK44_RS32055	COG0395	ABC-type sugar transport system, permease component
DVK44_RS32070	COG1802	Transcriptional regulator
DVK44_RS32075	COG2814	Major facilitator Superfamily
DVK44_RS32085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DVK44_RS32095	COG0745	RESPONSE REGULATOR receiver
DVK44_RS32100	COG2205	protein histidine kinase activity
DVK44_RS32105	COG1132	(ABC) transporter
DVK44_RS32130	COG0667	Aldo Keto reductase
DVK44_RS32140	COG0477	Major facilitator Superfamily
DVK44_RS32155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DVK44_RS32185	COG1024	Enoyl-CoA hydratase
DVK44_RS32190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DVK44_RS32225	COG0477	Major facilitator Superfamily
DVK44_RS32235	COG0702	epimerase
DVK44_RS32240	COG0300	oxidoreductase activity
DVK44_RS32260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS32265	COG3320	Male sterility
DVK44_RS32265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS32285	COG2409	Drug exporters of the RND superfamily
DVK44_RS32295	COG3321	synthase
DVK44_RS32295	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS32295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DVK44_RS32295	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS32295	COG0300	oxidoreductase activity
DVK44_RS32300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DVK44_RS32305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DVK44_RS32320	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS32325	COG0402	S-adenosylhomocysteine deaminase activity
DVK44_RS32335	COG1021	2,3-dihydroxybenzoate-AMP ligase
DVK44_RS32360	COG0477	Major facilitator Superfamily
DVK44_RS32375	COG0604	alcohol dehydrogenase
DVK44_RS32375	COG3321	synthase
DVK44_RS32375	COG0604	alcohol dehydrogenase
DVK44_RS32375	COG3321	synthase
DVK44_RS32385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DVK44_RS32385	COG2070	2-Nitropropane dioxygenase
DVK44_RS32395	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS32400	COG0736	holo-[acyl-carrier-protein] synthase activity
DVK44_RS32425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DVK44_RS32435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DVK44_RS32440	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS32460	COG0601	transmembrane transport
DVK44_RS32465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DVK44_RS32470	COG4172	Belongs to the ABC transporter superfamily
DVK44_RS32475	COG2390	Transcriptional regulator
DVK44_RS32480	COG1129	ABC transporter
DVK44_RS32485	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS32490	COG1879	ABC-type sugar transport system periplasmic component
DVK44_RS32500	COG1070	Carbohydrate kinase
DVK44_RS32510	COG1063	alcohol dehydrogenase
DVK44_RS32515	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS32520	COG1063	alcohol dehydrogenase
DVK44_RS32540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DVK44_RS32550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DVK44_RS32555	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DVK44_RS32560	COG4941	Belongs to the sigma-70 factor family
DVK44_RS32565	COG3795	YCII-related domain
DVK44_RS32575	COG4585	Histidine kinase
DVK44_RS32585	COG1063	alcohol dehydrogenase
DVK44_RS32590	COG1846	Transcriptional regulator
DVK44_RS32605	COG0189	ligase activity
DVK44_RS32620	COG1063	alcohol dehydrogenase
DVK44_RS32625	COG0477	Major facilitator Superfamily
DVK44_RS32630	COG0246	Mannitol dehydrogenase
DVK44_RS32665	COG3458	cephalosporin-C deacetylase activity
DVK44_RS32685	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS32690	COG1960	acyl-CoA dehydrogenase activity
DVK44_RS32705	COG0515	serine threonine protein kinase
DVK44_RS32710	COG2197	response regulator
DVK44_RS32715	COG4585	Histidine kinase
DVK44_RS32720	COG2409	Drug exporters of the RND superfamily
DVK44_RS32735	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS32740	COG0673	inositol 2-dehydrogenase activity
DVK44_RS32745	COG1609	Transcriptional regulator
DVK44_RS32775	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS32785	COG1609	Transcriptional regulator
DVK44_RS32790	COG0673	inositol 2-dehydrogenase activity
DVK44_RS32795	COG0673	inositol 2-dehydrogenase activity
DVK44_RS32800	COG0673	inositol 2-dehydrogenase activity
DVK44_RS32835	COG0395	ABC-type sugar transport system, permease component
DVK44_RS32840	COG4209	transmembrane transport
DVK44_RS32845	COG3458	cephalosporin-C deacetylase activity
DVK44_RS32855	COG3250	beta-galactosidase activity
DVK44_RS32860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVK44_RS32860	COG0515	serine threonine protein kinase
DVK44_RS32870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DVK44_RS32875	COG2207	Transcriptional regulator
DVK44_RS32885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS32890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS32895	COG1120	ATPase activity
DVK44_RS32910	COG3629	intracellular signal transduction
DVK44_RS32925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DVK44_RS32925	COG2124	cytochrome p450
DVK44_RS32945	COG3629	intracellular signal transduction
DVK44_RS32945	COG3903	Transcriptional regulator
DVK44_RS32980	COG1404	Belongs to the peptidase S8 family
DVK44_RS33000	COG0596	Alpha beta hydrolase
DVK44_RS33005	COG0243	molybdopterin cofactor binding
DVK44_RS33020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DVK44_RS33025	COG0402	S-adenosylhomocysteine deaminase activity
DVK44_RS33030	COG0813	purine-nucleoside phosphorylase activity
DVK44_RS33055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DVK44_RS33055	COG0235	Class ii aldolase
DVK44_RS33060	COG0235	Class ii aldolase
DVK44_RS33065	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
DVK44_RS33070	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DVK44_RS33085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS33090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS33095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DVK44_RS33100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DVK44_RS33125	COG2130	NADP-dependent
DVK44_RS33130	COG1309	transcriptional regulator
DVK44_RS33140	COG0667	Aldo Keto reductase
DVK44_RS33145	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS33155	COG0456	acetyltransferase
DVK44_RS33175	COG1802	Transcriptional regulator
DVK44_RS33190	COG1595	DNA-templated transcription, initiation
DVK44_RS33200	COG1131	(ABC) transporter
DVK44_RS33225	COG1472	Belongs to the glycosyl hydrolase 3 family
DVK44_RS33235	COG0395	ABC-type sugar transport system, permease component
DVK44_RS33275	COG0395	ABC-type sugar transport system, permease component
DVK44_RS33285	COG1653	transport
DVK44_RS33310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVK44_RS33310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVK44_RS33320	COG0604	alcohol dehydrogenase
DVK44_RS33320	COG3321	synthase
DVK44_RS33325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DVK44_RS33325	COG2070	2-Nitropropane dioxygenase
DVK44_RS33350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DVK44_RS33355	COG0583	DNA-binding transcription factor activity
DVK44_RS33360	COG2072	flavoprotein involved in K transport
DVK44_RS33380	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS33395	COG3903	Transcriptional regulator
DVK44_RS33395	COG3629	intracellular signal transduction
DVK44_RS33410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS33415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS33420	COG1120	ATPase activity
DVK44_RS33425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DVK44_RS33430	COG1132	(ABC) transporter
DVK44_RS33440	COG1132	(ABC) transporter
DVK44_RS33445	COG2382	esterase
DVK44_RS33455	COG2409	Drug exporters of the RND superfamily
DVK44_RS33470	COG0667	Aldo Keto reductase
DVK44_RS33480	COG1064	alcohol dehydrogenase
DVK44_RS33485	COG0702	epimerase
DVK44_RS33500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DVK44_RS33505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DVK44_RS33510	COG0583	DNA-binding transcription factor activity
DVK44_RS33520	COG1414	Transcriptional regulator
DVK44_RS33525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DVK44_RS33530	COG0765	amino acid transport
DVK44_RS33535	COG1126	abc transporter atp-binding protein
DVK44_RS33540	COG2040	homocysteine
DVK44_RS33565	COG3842	ATPase activity
DVK44_RS33570	COG1176	ABC-type spermidine putrescine transport system, permease component I
DVK44_RS33575	COG1177	transmembrane transport
DVK44_RS33595	COG1473	amidohydrolase
DVK44_RS33600	COG0028	Belongs to the TPP enzyme family
DVK44_RS33615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS33625	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS33635	COG0154	amidase activity
DVK44_RS33640	COG0154	amidase activity
DVK44_RS33655	COG0698	ribose 5-phosphate isomerase
DVK44_RS33680	COG0460	homoserine dehydrogenase
DVK44_RS33685	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS33710	COG0833	amino acid
DVK44_RS33770	COG2814	Major facilitator Superfamily
DVK44_RS33785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DVK44_RS33830	COG1222	aaa ATPase
DVK44_RS33925	COG3547	Transposase (IS116 IS110 IS902 family)
DVK44_RS33945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DVK44_RS34005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DVK44_RS34010	COG1819	glycosyl
DVK44_RS34065	COG0673	inositol 2-dehydrogenase activity
DVK44_RS34075	COG4948	Mandelate Racemase Muconate Lactonizing
DVK44_RS34080	COG0395	ABC-type sugar transport system, permease component
DVK44_RS34085	COG1175	transmembrane transport
DVK44_RS34095	COG2186	Transcriptional regulator
DVK44_RS34105	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS34120	COG4221	oxidoreductase activity
DVK44_RS34120	COG3321	synthase
DVK44_RS34120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DVK44_RS34120	COG0300	oxidoreductase activity
DVK44_RS34125	COG0367	asparagine synthase
DVK44_RS34135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DVK44_RS34140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DVK44_RS34150	COG1442	glycosyl transferase family 8
DVK44_RS34175	COG1131	(ABC) transporter
DVK44_RS34190	COG1501	Belongs to the glycosyl hydrolase 31 family
DVK44_RS34220	COG0583	DNA-binding transcription factor activity
DVK44_RS34225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DVK44_RS34255	COG1175	transmembrane transport
DVK44_RS34260	COG0395	ABC-type sugar transport system, permease component
DVK44_RS34270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DVK44_RS34275	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS34285	COG1129	ABC transporter
DVK44_RS34290	COG1869	D-ribose catabolic process
DVK44_RS34295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DVK44_RS34300	COG2188	Transcriptional regulator
DVK44_RS34305	COG3424	synthase
DVK44_RS34370	COG3425	synthase
DVK44_RS34380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DVK44_RS34405	COG3903	Transcriptional regulator
DVK44_RS34405	COG3629	intracellular signal transduction
DVK44_RS34415	COG0655	NAD(P)H dehydrogenase (quinone) activity
DVK44_RS34420	COG0596	Alpha beta hydrolase
DVK44_RS34425	COG0067	glutamate synthase
DVK44_RS34425	COG0069	glutamate synthase activity
DVK44_RS34425	COG0070	glutamate synthase
DVK44_RS34430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DVK44_RS34440	COG1404	Belongs to the peptidase S8 family
DVK44_RS34460	COG0667	Aldo Keto reductase
DVK44_RS34475	COG4172	Belongs to the ABC transporter superfamily
DVK44_RS34490	COG0747	negative chemotaxis
DVK44_RS34515	COG1132	(ABC) transporter
DVK44_RS34525	COG1120	ATPase activity
DVK44_RS34530	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS34535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DVK44_RS34570	COG0028	Belongs to the TPP enzyme family
DVK44_RS34575	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS34580	COG1414	Transcriptional regulator
DVK44_RS34585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DVK44_RS34610	COG0659	secondary active sulfate transmembrane transporter activity
DVK44_RS34625	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS34635	COG3119	arylsulfatase activity
DVK44_RS34635	COG3408	Glycogen debranching enzyme
DVK44_RS34645	COG1556	Lactate utilization protein
DVK44_RS34650	COG1139	Iron-sulfur cluster binding protein
DVK44_RS34655	COG0247	lactate metabolic process
DVK44_RS34660	COG1070	Carbohydrate kinase
DVK44_RS34665	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS34665	COG3347	Dehydrogenase
DVK44_RS34675	COG1129	ABC transporter
DVK44_RS34680	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS34690	COG1879	ABC-type sugar transport system periplasmic component
DVK44_RS34695	COG1609	Transcriptional regulator
DVK44_RS34715	COG1012	belongs to the aldehyde dehydrogenase family
DVK44_RS34730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DVK44_RS34735	COG3239	Fatty acid desaturase
DVK44_RS34760	COG2018	Roadblock/LC7 domain
DVK44_RS34780	COG1609	Transcriptional regulator
DVK44_RS34785	COG1070	Carbohydrate kinase
DVK44_RS34790	COG3347	Dehydrogenase
DVK44_RS34790	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS34795	COG4952	isomerase
DVK44_RS34800	COG1129	ABC transporter
DVK44_RS34820	COG3254	rhamnose metabolic process
DVK44_RS34830	COG2160	L-arabinose isomerase activity
DVK44_RS34835	COG1609	Transcriptional regulator
DVK44_RS34840	COG1295	ribonuclease BN
DVK44_RS34870	COG2304	oxidoreductase activity
DVK44_RS34880	COG1132	(ABC) transporter
DVK44_RS34900	COG0667	Aldo Keto reductase
DVK44_RS34915	COG3424	synthase
DVK44_RS34950	COG0667	Aldo Keto reductase
DVK44_RS34955	COG1278	Cold shock
DVK44_RS34965	COG0588	phosphoglycerate mutase activity
DVK44_RS34970	COG0254	rRNA binding
DVK44_RS34980	COG2814	Major facilitator Superfamily
DVK44_RS34985	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS34995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DVK44_RS35020	COG1175	transmembrane transport
DVK44_RS35025	COG0395	ABC-type sugar transport system, permease component
DVK44_RS35045	COG2340	Cysteine-rich secretory protein family
DVK44_RS35060	COG2186	Transcriptional regulator
DVK44_RS35070	COG2376	Dihydroxyacetone kinase
DVK44_RS35075	COG0698	ribose 5-phosphate isomerase
DVK44_RS35080	COG0149	triose-phosphate isomerase activity
DVK44_RS35085	COG1082	Xylose isomerase domain protein TIM barrel
DVK44_RS35090	COG2084	Dehydrogenase
DVK44_RS35100	COG3507	Belongs to the glycosyl hydrolase 43 family
DVK44_RS35115	COG1609	Transcriptional regulator
DVK44_RS35125	COG1175	transmembrane transport
DVK44_RS35130	COG0395	ABC-type sugar transport system, permease component
DVK44_RS35155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DVK44_RS35165	COG3290	protein histidine kinase activity
DVK44_RS35170	COG4565	transcriptional regulatory protein
DVK44_RS35175	COG2376	Dihydroxyacetone kinase
DVK44_RS35180	COG2376	Dihydroxyacetone kinase
DVK44_RS35215	COG1609	Transcriptional regulator
DVK44_RS35235	COG0395	ABC-type sugar transport system, permease component
DVK44_RS35240	COG4209	transmembrane transport
DVK44_RS35270	COG0395	ABC-type sugar transport system, permease component
DVK44_RS35275	COG1175	transmembrane transport
DVK44_RS35280	COG1653	transport
DVK44_RS35300	COG1609	Transcriptional regulator
DVK44_RS35305	COG0673	inositol 2-dehydrogenase activity
DVK44_RS35320	COG0596	Alpha beta hydrolase
DVK44_RS35325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DVK44_RS35330	COG3485	protocatechuate 3,4-dioxygenase
DVK44_RS35335	COG3485	protocatechuate 3,4-dioxygenase
DVK44_RS35340	COG0183	Belongs to the thiolase family
DVK44_RS35360	COG0438	transferase activity, transferring glycosyl groups
DVK44_RS35375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DVK44_RS35400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DVK44_RS35455	COG1129	ABC transporter
DVK44_RS35460	COG1172	Belongs to the binding-protein-dependent transport system permease family
DVK44_RS35475	COG0235	Class ii aldolase
DVK44_RS35480	COG3395	kinase activity
DVK44_RS35490	COG2610	gluconate transmembrane transporter activity
DVK44_RS35495	COG1349	DNA-binding transcription factor activity
DVK44_RS35515	COG2072	flavoprotein involved in K transport
DVK44_RS35520	COG0318	PFAM AMP-dependent synthetase and ligase
DVK44_RS35525	COG2264	protein methyltransferase activity
DVK44_RS35640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DVK44_RS35650	COG3940	Belongs to the glycosyl hydrolase 43 family
DVK44_RS35660	COG1609	Transcriptional regulator
DVK44_RS35670	COG1175	transmembrane transport
DVK44_RS35675	COG0395	ABC-type sugar transport system, permease component
DVK44_RS35685	COG0513	Belongs to the DEAD box helicase family
DVK44_RS35860	COG2423	ornithine cyclodeaminase activity
DVK44_RS35880	COG2814	Major facilitator Superfamily
DVK44_RS35905	COG0745	RESPONSE REGULATOR receiver
DVK44_RS35910	COG2205	protein histidine kinase activity
DVK44_RS35925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DVK44_RS35930	COG2197	response regulator
DVK44_RS35935	COG4585	Histidine kinase
DVK44_RS35945	COG1131	(ABC) transporter
DVK44_RS35950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DVK44_RS35960	COG1028	Short-chain dehydrogenase reductase Sdr
DVK44_RS35960	COG3321	synthase
DVK44_RS35960	COG0604	alcohol dehydrogenase
DVK44_RS35970	COG1741	Belongs to the pirin family
DVK44_RS35975	COG3619	membrane
DVK44_RS35980	COG1733	regulation of RNA biosynthetic process
DVK44_RS35985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DVK44_RS36010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DVK44_RS36270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases