Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 SUPERFAMILY SSF50129 7 171 1.07E-56 T 16-09-2016 IPR011032 GroES-like Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 SMART SM00829 14 341 2.6E-6 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 PANTHER PTHR11695:SF587 16 342 1.9E-204 T 16-09-2016 Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 Gene3D G3DSA:3.90.180.10 2 177 2.8E-68 T 16-09-2016 IPR011032 GroES-like Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 Gene3D G3DSA:3.40.50.720 178 292 4.6E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 SUPERFAMILY SSF51735 148 311 1.02E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 3.8E-30 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 PANTHER PTHR11695 16 342 1.9E-204 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS20915 e199126a1e8f6e35762c47f7532e78a9 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 3.8E-20 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS07975 7c4bfaed81c471b843b5ce7a2662b31f 264 PANTHER PTHR10108 35 199 1.7E-17 T 16-09-2016 Spa2297_RS07975 7c4bfaed81c471b843b5ce7a2662b31f 264 Pfam PF13489 Methyltransferase domain 39 199 1.5E-11 T 16-09-2016 Spa2297_RS07975 7c4bfaed81c471b843b5ce7a2662b31f 264 SUPERFAMILY SSF53335 9 200 5.12E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS07975 7c4bfaed81c471b843b5ce7a2662b31f 264 Gene3D G3DSA:3.40.50.150 20 203 2.3E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SUPERFAMILY SSF54814 180 258 9.16E-28 T 16-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Gene3D G3DSA:3.30.300.20 179 257 4.4E-33 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Gene3D G3DSA:3.30.1480.10 3 102 3.3E-30 T 16-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Pfam PF08529 NusA N-terminal domain 6 61 3.7E-8 T 16-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Pfam PF08529 NusA N-terminal domain 64 103 2.8E-8 T 16-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 322 3.7E-105 T 16-09-2016 IPR010213 Transcription termination factor NusA GO:0003723 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Gene3D G3DSA:3.30.300.20 258 326 9.4E-31 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SMART SM00322 210 273 3.4 T 16-09-2016 IPR004087 K Homology domain GO:0003676 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SMART SM00322 282 340 0.5 T 16-09-2016 IPR004087 K Homology domain GO:0003676 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Pfam PF13184 NusA-like KH domain 210 278 1.4E-25 T 16-09-2016 IPR025249 KH domain, NusA-like GO:0003723 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 PANTHER PTHR22648:SF0 1 320 7.9E-131 T 16-09-2016 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Gene3D G3DSA:2.40.50.140 109 178 5.1E-25 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SUPERFAMILY SSF50249 112 179 3.43E-15 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SUPERFAMILY SSF54814 259 324 7.19E-16 T 16-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SUPERFAMILY SSF69705 3 102 4.19E-27 T 16-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 340 26.108 T 16-09-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 PANTHER PTHR22648 1 320 7.9E-131 T 16-09-2016 Spa2297_RS24155 b2f65396d97e14ebf64e70c17d7cae56 340 SMART SM00316 113 178 3.2E-4 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS33995 ba50ac269e954753b2b64e342c347490 177 PANTHER PTHR10668:SF83 25 177 6.1E-47 T 16-09-2016 Spa2297_RS33995 ba50ac269e954753b2b64e342c347490 177 Gene3D G3DSA:3.40.50.720 23 125 1.9E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS33995 ba50ac269e954753b2b64e342c347490 177 PANTHER PTHR10668 25 177 6.1E-47 T 16-09-2016 Spa2297_RS33995 ba50ac269e954753b2b64e342c347490 177 SUPERFAMILY SSF51905 25 159 4.63E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS33995 ba50ac269e954753b2b64e342c347490 177 Pfam PF13450 NAD(P)-binding Rossmann-like domain 32 71 9.0E-11 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 PANTHER PTHR21262:SF0 27 719 4.6E-232 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SUPERFAMILY SSF55021 642 717 2.35E-6 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Gene3D G3DSA:3.30.460.10 244 376 3.7E-25 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Gene3D G3DSA:3.30.70.260 653 714 1.1E-4 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SUPERFAMILY SSF81271 446 504 1.9E-9 T 16-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 PANTHER PTHR21262 27 719 4.6E-232 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Pfam PF04607 Region found in RelA / SpoT proteins 315 383 1.7E-13 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SMART SM00471 95 205 7.5E-12 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Gene3D G3DSA:3.10.20.30 445 505 6.2E-11 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Pfam PF02824 TGS domain 446 504 7.4E-14 T 16-09-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SUPERFAMILY SSF81301 244 390 8.01E-34 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Pfam PF13328 HD domain 80 227 3.2E-39 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 Pfam PF13291 ACT domain 643 716 1.6E-8 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SUPERFAMILY SSF109604 60 242 2.82E-61 T 16-09-2016 Spa2297_RS24525 1af2fc55cd97c51e4e930176298caac6 724 SMART SM00954 287 396 4.0E-24 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 SUPERFAMILY SSF55931 2 360 6.28E-92 T 16-09-2016 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 PANTHER PTHR36510:SF2 1 362 1.7E-176 T 16-09-2016 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 363 77.376 T 16-09-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 PANTHER PTHR36510 1 362 1.7E-176 T 16-09-2016 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 287 2.5E-107 T 16-09-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Spa2297_RS02020 25fbe6bdfc7e503843c4729332372479 363 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 283 1.4E-76 T 16-09-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Spa2297_RS14655 a9734e2d9a9d89f75ae920912fccae97 221 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 25 209 5.1E-60 T 16-09-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS14655 a9734e2d9a9d89f75ae920912fccae97 221 Pfam PF01048 Phosphorylase superfamily 32 204 1.6E-12 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS14655 a9734e2d9a9d89f75ae920912fccae97 221 Hamap MF_00991 Futalosine hydrolase [mqnB]. 19 211 24.687 T 16-09-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS14655 a9734e2d9a9d89f75ae920912fccae97 221 Gene3D G3DSA:3.40.50.1580 21 219 5.5E-49 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS14655 a9734e2d9a9d89f75ae920912fccae97 221 SUPERFAMILY SSF53167 32 194 2.09E-26 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 SUPERFAMILY SSF51735 7 170 2.03E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 147 252 7.9E-10 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 PANTHER PTHR22604:SF120 10 359 9.8E-94 T 16-09-2016 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 Gene3D G3DSA:3.40.50.720 6 156 6.1E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 122 2.8E-18 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 SUPERFAMILY SSF55347 142 294 1.16E-27 T 16-09-2016 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 Gene3D G3DSA:3.30.360.10 302 351 1.9E-39 T 16-09-2016 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 Gene3D G3DSA:3.30.360.10 157 267 1.9E-39 T 16-09-2016 Spa2297_RS31425 487838b7053f518b877ee403ab8c886b 382 PANTHER PTHR22604 10 359 9.8E-94 T 16-09-2016 Spa2297_RS07745 639415be8fdf9e209cb1b792edac768d 105 Gene3D G3DSA:2.102.10.10 1 103 5.4E-34 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS07745 639415be8fdf9e209cb1b792edac768d 105 SUPERFAMILY SSF50022 1 103 9.3E-32 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS07745 639415be8fdf9e209cb1b792edac768d 105 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 3.8E-20 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS07745 639415be8fdf9e209cb1b792edac768d 105 PANTHER PTHR21496 1 99 4.1E-29 T 16-09-2016 Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 SMART SM00346 1 85 0.0083 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 PANTHER PTHR30136:SF3 1 240 1.7E-61 T 16-09-2016 Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 SUPERFAMILY SSF55781 56 229 1.11E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 Gene3D G3DSA:1.10.10.10 1 65 3.1E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 Pfam PF01614 Bacterial transcriptional regulator 126 214 2.5E-14 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 PANTHER PTHR30136 1 240 1.7E-61 T 16-09-2016 Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 SUPERFAMILY SSF46785 1 64 2.22E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 Gene3D G3DSA:3.30.450.40 75 237 5.8E-24 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16345 22db1b6ca462e9ae96098b9efed7abfa 241 Pfam PF09339 IclR helix-turn-helix domain 1 50 5.4E-12 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS26920 1fdb8569e4b44fe1cd2203c85eb60474 170 PANTHER PTHR13078 1 163 3.8E-63 T 16-09-2016 Spa2297_RS26920 1fdb8569e4b44fe1cd2203c85eb60474 170 SUPERFAMILY SSF54637 2 148 3.95E-42 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS26920 1fdb8569e4b44fe1cd2203c85eb60474 170 Gene3D G3DSA:3.10.129.10 2 149 4.4E-42 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS26920 1fdb8569e4b44fe1cd2203c85eb60474 170 Pfam PF01575 MaoC like domain 12 115 3.5E-14 T 16-09-2016 IPR002539 MaoC-like domain Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 Gene3D G3DSA:3.30.420.40 1 106 3.7E-40 T 16-09-2016 Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 Pfam PF00480 ROK family 4 162 1.2E-14 T 16-09-2016 IPR000600 ROK family Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 Pfam PF00480 ROK family 176 243 8.4E-5 T 16-09-2016 IPR000600 ROK family Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 Gene3D G3DSA:3.30.420.40 107 244 3.4E-37 T 16-09-2016 Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 PANTHER PTHR18964:SF138 1 244 4.1E-88 T 16-09-2016 Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 SUPERFAMILY SSF53067 1 244 3.82E-38 T 16-09-2016 Spa2297_RS21425 676213e13dfaed3f3a3ec723928a17a8 246 PANTHER PTHR18964 1 244 4.1E-88 T 16-09-2016 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 PANTHER PTHR26402 19 237 5.4E-95 T 16-09-2016 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 Gene3D G3DSA:1.10.10.10 143 238 8.1E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 SMART SM00862 165 236 6.7E-26 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 SUPERFAMILY SSF46894 142 237 4.54E-27 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 Pfam PF00072 Response regulator receiver domain 21 130 8.1E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 SMART SM00448 19 130 3.3E-39 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 Gene3D G3DSA:3.40.50.2300 11 138 6.3E-41 T 16-09-2016 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 PANTHER PTHR26402:SF50 19 237 5.4E-95 T 16-09-2016 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 236 3.4E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS22845 0461bdd70a8d71877f48e72a4d0bc6f4 240 SUPERFAMILY SSF52172 15 139 6.26E-40 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 Gene3D G3DSA:1.10.10.60 262 311 7.7E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 SUPERFAMILY SSF46689 260 311 2.42E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 Gene3D G3DSA:3.40.50.880 1 211 2.7E-60 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 Gene3D G3DSA:1.10.10.60 212 261 1.0E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 SUPERFAMILY SSF46689 207 257 1.63E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 SMART SM00342 224 307 3.3E-28 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 SUPERFAMILY SSF52317 1 189 2.39E-52 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 Pfam PF12833 Helix-turn-helix domain 230 309 5.6E-24 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 Pfam PF01965 DJ-1/PfpI family 1 170 1.0E-27 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 PANTHER PTHR11019 49 315 2.8E-83 T 16-09-2016 Spa2297_RS18765 802e526b25df1ba4167ffc45fc7f45ca 317 PANTHER PTHR11019:SF58 49 315 2.8E-83 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 SUPERFAMILY SSF53067 77 389 2.21E-60 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 Gene3D G3DSA:3.30.420.40 77 214 7.1E-42 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 PANTHER PTHR18964:SF109 58 389 1.9E-95 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 SUPERFAMILY SSF46785 7 72 5.18E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 PANTHER PTHR18964 58 389 1.9E-95 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 Gene3D G3DSA:1.10.10.10 11 72 4.3E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 Pfam PF00480 ROK family 78 386 8.2E-60 T 16-09-2016 IPR000600 ROK family Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 Gene3D G3DSA:3.30.420.40 215 369 5.5E-49 T 16-09-2016 Spa2297_RS27340 3c89979841e5d5ee5c9b5dcf72df3546 393 ProSitePatterns PS01125 ROK family signature. 209 236 - T 16-09-2016 IPR000600 ROK family Spa2297_RS08735 bb0460e954b6ec9801a945ac2e959106 254 Gene3D G3DSA:3.60.10.10 22 248 6.6E-8 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS08735 bb0460e954b6ec9801a945ac2e959106 254 SUPERFAMILY SSF56219 20 248 2.22E-28 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS08735 bb0460e954b6ec9801a945ac2e959106 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 25 241 1.6E-15 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 PANTHER PTHR21599 1 399 2.1E-254 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 Pfam PF02595 Glycerate kinase family 5 375 1.2E-127 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 PANTHER PTHR21599:SF5 1 399 2.1E-254 T 16-09-2016 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 5 376 3.7E-142 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 PIRSF PIRSF006078 3 379 1.8E-104 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 Gene3D G3DSA:3.40.50.10350 265 376 3.0E-27 T 16-09-2016 IPR018197 Glycerate kinase, restriction-enzyme-like fold Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 Gene3D G3DSA:3.90.1510.10 45 264 3.0E-81 T 16-09-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 Spa2297_RS08835 27deb758d8ce0c4e71ff6807d4819ade 404 SUPERFAMILY SSF110738 4 377 3.27E-112 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 27 440 2.9E-128 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PANTHER PTHR11482:SF5 9 437 5.7E-147 T 16-09-2016 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 326 344 2.4E-24 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 409 431 2.4E-24 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 181 190 2.4E-24 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 93 110 2.4E-24 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 Gene3D G3DSA:2.40.37.10 294 441 4.3E-44 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 SUPERFAMILY SSF50621 287 441 1.28E-47 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PANTHER PTHR11482 9 437 5.7E-147 T 16-09-2016 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 55 308 9.2E-56 T 16-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 209 222 1.5E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 298 317 1.5E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 107 1.5E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 399 412 1.5E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 75 93 1.5E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 SUPERFAMILY SSF51419 46 310 2.47E-73 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 75 93 - T 16-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 315 417 2.2E-15 T 16-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 Gene3D G3DSA:3.20.20.10 55 293 1.7E-82 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS14130 aeba8b2fa621d1629ddc55b9f6ee5fd5 444 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 35 442 38.561 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 SMART SM00354 10 80 5.0E-20 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.3E-15 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 PANTHER PTHR30146:SF45 9 345 2.7E-142 T 16-09-2016 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 PANTHER PTHR30146 9 345 2.7E-142 T 16-09-2016 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 SUPERFAMILY SSF47413 9 65 7.74E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 SUPERFAMILY SSF53822 84 329 3.46E-47 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 Gene3D G3DSA:1.10.260.40 9 59 1.3E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 Gene3D G3DSA:3.40.50.2300 60 190 5.4E-22 T 16-09-2016 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 Gene3D G3DSA:3.40.50.2300 191 321 1.0E-29 T 16-09-2016 Spa2297_RS28890 ba84ea2154d6cd691818ffc597f4a75c 348 Pfam PF13377 Periplasmic binding protein-like domain 185 342 5.6E-32 T 16-09-2016 Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 55 164 4.8E-24 T 16-09-2016 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 SUPERFAMILY SSF56601 238 540 1.82E-55 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 PANTHER PTHR30627 204 539 1.1E-151 T 16-09-2016 Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 PANTHER PTHR30627:SF4 204 539 1.1E-151 T 16-09-2016 Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 Gene3D G3DSA:3.40.710.10 247 539 1.6E-60 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS17090 a379b70eed7bb8166e73c9047444949f 544 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 536 1.4E-40 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 Gene3D G3DSA:3.40.190.100 125 258 5.3E-22 T 16-09-2016 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 SUPERFAMILY SSF53850 36 318 1.09E-56 T 16-09-2016 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 307 7.0E-49 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 PANTHER PTHR30177:SF0 2 312 4.0E-108 T 16-09-2016 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 Gene3D G3DSA:3.40.190.10 259 317 2.5E-20 T 16-09-2016 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 Gene3D G3DSA:3.40.190.10 38 116 2.5E-20 T 16-09-2016 Spa2297_RS20385 555097ae6bde95e723f1d3c6b1b8cebb 318 PANTHER PTHR30177 2 312 4.0E-108 T 16-09-2016 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 SMART SM00421 154 211 2.2E-25 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 Gene3D G3DSA:3.40.50.2300 2 123 5.5E-36 T 16-09-2016 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 4.5E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 PANTHER PTHR26402 3 218 3.2E-97 T 16-09-2016 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 SUPERFAMILY SSF52172 2 135 5.41E-33 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 SUPERFAMILY SSF46894 146 217 9.86E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 Pfam PF00072 Response regulator receiver domain 5 117 1.5E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 PANTHER PTHR26402:SF564 3 218 3.2E-97 T 16-09-2016 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 SMART SM00448 3 116 1.6E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 Gene3D G3DSA:1.10.10.10 124 218 1.0E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 6.4E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 6.4E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18255 852c64468b59135b120b6d9af3c0083c 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 6.4E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PANTHER PTHR11751:SF10 13 85 1.1E-26 T 16-09-2016 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 4.3E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 Gene3D G3DSA:3.40.1410.10 85 243 5.0E-49 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 Gene3D G3DSA:1.10.10.10 12 84 5.9E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 SUPERFAMILY SSF64288 70 244 1.19E-47 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PANTHER PTHR11751 13 85 1.1E-26 T 16-09-2016 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 SMART SM00345 23 82 5.7E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 4.0E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 4.0E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 SUPERFAMILY SSF46785 12 86 3.73E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PANTHER PTHR11751:SF10 131 154 1.1E-26 T 16-09-2016 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 SMART SM00866 102 240 2.5E-36 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 Pfam PF07702 UTRA domain 103 239 7.1E-38 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS26485 1abf1925445aff694379686fae9e724e 249 PANTHER PTHR11751 131 154 1.1E-26 T 16-09-2016 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 PANTHER PTHR26402 19 219 4.2E-137 T 16-09-2016 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 PANTHER PTHR26402:SF523 19 219 4.2E-137 T 16-09-2016 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 Gene3D G3DSA:3.40.50.2300 21 117 7.9E-8 T 16-09-2016 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 SUPERFAMILY SSF52172 18 122 3.7E-10 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.8E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.8E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.8E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 SUPERFAMILY SSF46894 146 219 1.63E-18 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 SMART SM00421 156 213 1.0E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 Gene3D G3DSA:1.10.10.10 143 218 1.5E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 2.5E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25350 2079883859cb9072bdd68f5c0b29c2ab 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 SUPERFAMILY SSF54909 88 167 1.25E-15 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 SUPERFAMILY SSF46785 25 80 4.04E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 SMART SM00344 26 130 3.0E-37 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 Pfam PF13404 AsnC-type helix-turn-helix domain 26 66 2.4E-15 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 ProSitePatterns PS00519 AsnC-type HTH domain signature. 44 70 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 53 2.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 42 2.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 53 72 2.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 PANTHER PTHR30154:SF2 18 171 3.4E-53 T 16-09-2016 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 Gene3D G3DSA:1.10.10.10 25 73 4.6E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 Gene3D G3DSA:3.30.70.920 79 165 7.9E-17 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 PANTHER PTHR30154 18 171 3.4E-53 T 16-09-2016 Spa2297_RS23890 03a8400b1e48d8a0cb045852d1188d60 171 Pfam PF01037 Lrp/AsnC ligand binding domain 91 160 1.5E-15 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 SMART SM00862 148 224 1.5E-22 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 SMART SM00448 2 112 2.8E-37 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 PANTHER PTHR26402:SF399 2 229 5.1E-83 T 16-09-2016 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 Gene3D G3DSA:3.40.50.2300 1 121 1.9E-35 T 16-09-2016 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 PANTHER PTHR26402 2 229 5.1E-83 T 16-09-2016 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 Pfam PF00072 Response regulator receiver domain 4 112 3.9E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 SUPERFAMILY SSF52172 1 184 2.28E-37 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 9.8E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS14145 920b41894b39ee070487768181897d9a 230 Gene3D G3DSA:1.10.10.10 127 226 1.5E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06780 738b6e6855b53eb6f4b0c0ea794357ac 336 PANTHER PTHR22916 10 227 2.7E-27 T 16-09-2016 Spa2297_RS06780 738b6e6855b53eb6f4b0c0ea794357ac 336 Pfam PF00535 Glycosyl transferase family 2 11 176 1.2E-22 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS06780 738b6e6855b53eb6f4b0c0ea794357ac 336 Gene3D G3DSA:3.90.550.10 10 229 1.5E-33 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS06780 738b6e6855b53eb6f4b0c0ea794357ac 336 SUPERFAMILY SSF53448 9 234 8.04E-39 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Gene3D G3DSA:3.40.50.300 313 515 3.4E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Hamap MF_01973 Lon protease [lon]. 13 796 58.058 T 16-09-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 SMART SM00464 12 203 3.2E-20 T 16-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 SUPERFAMILY SSF54211 616 794 4.55E-52 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 SUPERFAMILY SSF88697 12 202 1.17E-22 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 586 796 2.8E-75 T 16-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 750 768 3.1E-50 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 371 390 3.1E-50 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 727 746 3.1E-50 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 697 716 3.1E-50 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 616 632 3.1E-50 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PANTHER PTHR10046:SF24 1 800 0.0 T 16-09-2016 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 SMART SM00382 363 508 2.0E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 368 503 2.4E-20 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Gene3D G3DSA:3.30.230.10 611 795 2.1E-68 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PIRSF PIRSF001174 1 798 5.7E-240 T 16-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 PANTHER PTHR10046 1 800 0.0 T 16-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 TIGRFAM TIGR00763 lon: endopeptidase La 14 795 1.2E-234 T 16-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 700 708 - T 16-09-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 SUPERFAMILY SSF52540 314 577 3.66E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 202 3.5E-15 T 16-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 Spa2297_RS22330 168519a244464f68d8862d706d5b35b0 810 Gene3D G3DSA:1.10.8.60 516 599 1.6E-26 T 16-09-2016 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 PANTHER PTHR21343 1 224 2.3E-62 T 16-09-2016 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 Pfam PF13500 AAA domain 4 199 2.0E-30 T 16-09-2016 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 Gene3D G3DSA:3.40.50.300 1 206 4.9E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 211 23.239 T 16-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 PIRSF PIRSF006755 1 203 7.7E-34 T 16-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 PANTHER PTHR21343:SF0 1 224 2.3E-62 T 16-09-2016 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 8.6E-30 T 16-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04545 80c348f964e92e6566838fde66c32e45 238 SUPERFAMILY SSF52540 1 200 2.46E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 16-09-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PANTHER PTHR11817 1 472 2.5E-221 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 2.6E-28 T 16-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 SUPERFAMILY SSF50800 70 164 2.97E-26 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 SUPERFAMILY SSF52935 320 470 6.28E-39 T 16-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Gene3D G3DSA:3.20.20.60 2 72 1.4E-103 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Gene3D G3DSA:3.20.20.60 167 322 1.4E-103 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Gene3D G3DSA:3.40.1380.20 323 467 1.3E-42 T 16-09-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 468 3.3E-164 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 SUPERFAMILY SSF51621 1 74 4.89E-96 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 SUPERFAMILY SSF51621 154 337 4.89E-96 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 1.1E-126 T 16-09-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 Gene3D G3DSA:2.40.33.10 73 166 4.6E-30 T 16-09-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 214 240 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 241 265 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 291 309 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 266 290 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 184 198 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22925 4e12d9434f1e2e06964e160355f09dea 476 PRINTS PR01050 Pyruvate kinase family signature 310 326 6.3E-62 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 4.7E-29 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.3E-15 T 16-09-2016 IPR027399 Alcohol dehydrogenase GroES-associated Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Gene3D G3DSA:3.40.50.720 296 337 1.5E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Gene3D G3DSA:3.40.50.720 181 261 1.5E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 PANTHER PTHR11695 12 259 2.1E-150 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 PANTHER PTHR11695:SF281 12 259 2.1E-150 T 16-09-2016 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 SUPERFAMILY SSF51735 156 355 6.36E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 SUPERFAMILY SSF50129 1 177 2.13E-58 T 16-09-2016 IPR011032 GroES-like Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 PANTHER PTHR11695:SF281 294 396 2.1E-150 T 16-09-2016 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Gene3D G3DSA:3.90.180.10 1 180 2.1E-50 T 16-09-2016 IPR011032 GroES-like Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 Pfam PF00107 Zinc-binding dehydrogenase 189 263 1.4E-11 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS27910 afe972bf3cf19819c5a1dbad7e143a08 396 PANTHER PTHR11695 294 396 2.1E-150 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 SUPERFAMILY SSF102114 113 342 1.7E-14 T 16-09-2016 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 367 8.3E-95 T 16-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 PIRSF PIRSF006004 14 368 1.4E-123 T 16-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 19 368 65.621 T 16-09-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 Gene3D G3DSA:3.20.20.70 120 338 7.5E-15 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 PANTHER PTHR30544:SF5 1 368 2.6E-164 T 16-09-2016 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 Pfam PF04055 Radical SAM superfamily 124 295 4.4E-15 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS23845 367ba41f0e2a78ba2c3b01602d24e79c 368 PANTHER PTHR30544 1 368 2.6E-164 T 16-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 PANTHER PTHR11748:SF65 249 595 5.2E-291 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Gene3D G3DSA:1.10.1060.10 538 653 2.9E-16 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 SUPERFAMILY SSF55103 299 553 3.27E-44 T 16-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 573 584 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 PANTHER PTHR11748 1 212 5.2E-291 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 PANTHER PTHR11748 249 595 5.2E-291 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Pfam PF13534 4Fe-4S dicluster domain 573 642 5.9E-8 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Pfam PF01565 FAD binding domain 70 206 3.9E-33 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Pfam PF02913 FAD linked oxidases, C-terminal domain 296 546 1.3E-54 T 16-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 PANTHER PTHR11748:SF65 1 212 5.2E-291 T 16-09-2016 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Gene3D G3DSA:3.30.465.10 126 293 1.8E-16 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Pfam PF02754 Cysteine-rich domain 873 951 0.031 T 16-09-2016 IPR004017 Cysteine-rich domain Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Gene3D G3DSA:3.30.43.10 28 120 4.6E-19 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 SUPERFAMILY SSF56176 35 293 3.88E-53 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 Gene3D G3DSA:1.10.45.10 510 537 5.5E-4 T 16-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Spa2297_RS00980 ec53f2e97dcf83955c45a857bdfe67b0 974 SUPERFAMILY SSF46548 531 652 1.1E-14 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS02385 6326dd861893007038cbf755bbb7a1a5 319 SUPERFAMILY SSF51735 16 316 1.68E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02385 6326dd861893007038cbf755bbb7a1a5 319 PANTHER PTHR10366 16 315 1.3E-21 T 16-09-2016 Spa2297_RS02385 6326dd861893007038cbf755bbb7a1a5 319 Pfam PF13460 NAD(P)H-binding 16 123 2.2E-7 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02385 6326dd861893007038cbf755bbb7a1a5 319 Gene3D G3DSA:3.40.50.720 16 309 4.7E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 SUPERFAMILY SSF64288 57 248 3.77E-31 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 Gene3D G3DSA:3.40.1410.10 70 245 5.2E-55 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 SMART SM00866 98 242 5.5E-15 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 PANTHER PTHR11751 1 72 4.0E-14 T 16-09-2016 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 PANTHER PTHR11751 214 232 4.0E-14 T 16-09-2016 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 SMART SM00345 10 69 3.9E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 PANTHER PTHR11751:SF432 1 72 4.0E-14 T 16-09-2016 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 PANTHER PTHR11751:SF432 214 232 4.0E-14 T 16-09-2016 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 2.3E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 Gene3D G3DSA:1.10.10.10 2 69 5.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 Pfam PF07702 UTRA domain 112 240 1.5E-19 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17350 27aa13c474b196ac7f755b155d20dcfb 251 SUPERFAMILY SSF46785 2 78 9.03E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Gene3D G3DSA:3.40.50.300 1012 1073 1.9E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Gene3D G3DSA:3.40.50.300 875 923 1.9E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Gene3D G3DSA:3.40.50.300 757 798 1.9E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887 631 862 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 SUPERFAMILY SSF52540 893 1074 8.5E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 SUPERFAMILY SSF52540 740 816 8.5E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 SMART SM00382 631 773 2.8E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Pfam PF13604 AAA domain 628 769 1.4E-29 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887 1024 1069 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887 892 920 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887:SF284 631 862 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Pfam PF13538 UvrD-like helicase C-terminal domain 1024 1068 1.1E-13 T 16-09-2016 IPR027785 UvrD-like helicase C-terminal domain Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887:SF284 1024 1069 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 PANTHER PTHR10887:SF284 892 920 1.6E-17 T 16-09-2016 Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 SUPERFAMILY SSF52540 631 775 6.48E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22570 c1347596d6361ee7851b35cfe63cc2dc 1270 Gene3D G3DSA:3.40.50.300 623 756 2.9E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 Pfam PF10138 vWA found in TerF C terminus 257 473 3.8E-83 T 16-09-2016 IPR019303 vWA found in TerF C terminus Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 PANTHER PTHR32097 1 435 2.8E-148 T 16-09-2016 Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 SMART SM00327 257 446 8.2E-14 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 PANTHER PTHR32097:SF4 1 435 2.8E-148 T 16-09-2016 Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 Gene3D G3DSA:2.60.60.30 19 171 4.6E-32 T 16-09-2016 Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 SUPERFAMILY SSF53300 259 447 1.01E-8 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS16325 4d987c490c50793734c8185a0fe71228 473 Pfam PF02342 TerD domain 3 173 2.3E-44 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 SUPERFAMILY SSF46689 30 90 5.55E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 PANTHER PTHR30514 17 291 7.9E-81 T 16-09-2016 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 Pfam PF01418 Helix-turn-helix domain, rpiR family 29 89 4.2E-11 T 16-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 PANTHER PTHR30514:SF3 17 291 7.9E-81 T 16-09-2016 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 SUPERFAMILY SSF53697 108 248 9.34E-10 T 16-09-2016 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 Gene3D G3DSA:3.40.50.10490 81 250 1.1E-7 T 16-09-2016 Spa2297_RS13345 bc0f23565c6fbe4a3dda2b6427386372 292 Gene3D G3DSA:1.10.10.10 30 80 1.6E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 PANTHER PTHR22642:SF2 1 529 4.9E-141 T 16-09-2016 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 SUPERFAMILY SSF51556 65 122 3.58E-39 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 SUPERFAMILY SSF51556 184 463 3.58E-39 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 PANTHER PTHR22642 1 529 4.9E-141 T 16-09-2016 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 SUPERFAMILY SSF51338 465 504 5.32E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 SUPERFAMILY SSF51338 9 66 5.32E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 Gene3D G3DSA:2.30.40.10 4 119 2.6E-13 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 Pfam PF07969 Amidohydrolase family 54 529 4.4E-106 T 16-09-2016 IPR013108 Amidohydrolase 3 Spa2297_RS05345 3e511cf8a93a2683383cc212f6f164c4 534 Gene3D G3DSA:3.20.20.140 190 462 9.1E-34 T 16-09-2016 Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 SUPERFAMILY SSF52540 102 288 6.48E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 70 297 2.5E-111 T 16-09-2016 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 PANTHER PTHR34383:SF2 63 321 2.9E-139 T 16-09-2016 Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 PANTHER PTHR34383 63 321 2.9E-139 T 16-09-2016 Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 71 296 2.2E-100 T 16-09-2016 IPR022488 Polyphosphate kinase-2-related Spa2297_RS30880 5a2368c2ca6cf01fe42a3c62a2cf3801 343 Gene3D G3DSA:3.40.50.300 62 315 1.7E-105 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 Gene3D G3DSA:3.60.40.10 188 443 8.6E-48 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 SMART SM00332 178 441 1.2E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 PANTHER PTHR10994 1 242 5.1E-144 T 16-09-2016 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 PANTHER PTHR10994:SF7 1 242 5.1E-144 T 16-09-2016 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 SUPERFAMILY SSF81606 188 443 3.53E-38 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 SMART SM00331 192 443 5.0E-4 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11305 44c60f6357a6caf8b43727460a6fdb2f 453 Pfam PF13672 Protein phosphatase 2C 200 405 2.6E-14 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 PRINTS PR00364 Disease resistance protein signature 489 503 3.5E-9 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 PRINTS PR00364 Disease resistance protein signature 327 342 3.5E-9 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 PRINTS PR00364 Disease resistance protein signature 404 418 3.5E-9 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SUPERFAMILY SSF48452 861 978 3.34E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Pfam PF00486 Transcriptional regulatory protein, C terminal 45 99 2.0E-8 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 PANTHER PTHR22845:SF4 164 771 3.9E-207 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 PANTHER PTHR22845 164 771 3.9E-207 T 16-09-2016 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Pfam PF03704 Bacterial transcriptional activator domain 119 263 1.1E-43 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SUPERFAMILY SSF48452 116 286 6.07E-35 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Pfam PF00931 NB-ARC domain 327 509 7.1E-14 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SUPERFAMILY SSF46894 26 99 7.37E-12 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM00862 39 111 2.5E-9 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Gene3D G3DSA:1.25.40.10 190 251 2.2E-21 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Gene3D G3DSA:1.25.40.10 740 972 2.2E-21 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SUPERFAMILY SSF48452 782 895 2.64E-14 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM01043 119 263 3.9E-50 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Gene3D G3DSA:3.40.50.300 303 420 2.0E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 Gene3D G3DSA:1.10.10.10 46 99 8.2E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SUPERFAMILY SSF52540 281 555 4.99E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM00028 941 974 2.1 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM00028 862 895 1.2 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM00028 782 815 410.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS14325 9a4618576fee0b79d0d4552bbc05636a 992 SMART SM00028 822 855 3.2 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 SUPERFAMILY SSF55781 76 241 3.07E-23 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 PANTHER PTHR30136:SF3 1 237 3.6E-69 T 16-09-2016 Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 PANTHER PTHR30136 1 237 3.6E-69 T 16-09-2016 Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 SUPERFAMILY SSF46785 13 80 9.1E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 Gene3D G3DSA:3.30.450.40 87 241 4.2E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 Gene3D G3DSA:1.10.10.10 13 80 2.9E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12095 520d822cf8d443d99550ce5988b5e612 252 Pfam PF01614 Bacterial transcriptional regulator 133 233 1.1E-13 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS24215 9aa40ec68f4d3ac50a97ecaec50302fd 925 Pfam PF13614 AAA domain 580 726 1.5E-10 T 16-09-2016 IPR025669 AAA domain Spa2297_RS24215 9aa40ec68f4d3ac50a97ecaec50302fd 925 PANTHER PTHR13696 559 828 5.6E-48 T 16-09-2016 Spa2297_RS24215 9aa40ec68f4d3ac50a97ecaec50302fd 925 SUPERFAMILY SSF52540 578 818 8.72E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24215 9aa40ec68f4d3ac50a97ecaec50302fd 925 Gene3D G3DSA:3.40.50.300 579 816 1.2E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24215 9aa40ec68f4d3ac50a97ecaec50302fd 925 PANTHER PTHR13696:SF1 559 828 5.6E-48 T 16-09-2016 Spa2297_RS09830 108b80a13dee521693f5ac3dbda1c343 411 Gene3D G3DSA:1.10.260.40 2 63 4.4E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09830 108b80a13dee521693f5ac3dbda1c343 411 Gene3D G3DSA:1.25.40.10 298 366 6.8E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09830 108b80a13dee521693f5ac3dbda1c343 411 SUPERFAMILY SSF48452 168 360 2.35E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS10175 a0877cf604aa2643bb85b9c69bca4b57 379 PANTHER PTHR33371 39 365 3.9E-156 T 16-09-2016 Spa2297_RS10175 a0877cf604aa2643bb85b9c69bca4b57 379 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 186 302 2.3E-9 T 16-09-2016 IPR024516 Mammalian cell entry, C-terminal Spa2297_RS10175 a0877cf604aa2643bb85b9c69bca4b57 379 PANTHER PTHR33371:SF6 39 365 3.9E-156 T 16-09-2016 Spa2297_RS10175 a0877cf604aa2643bb85b9c69bca4b57 379 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 31 319 1.6E-65 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10175 a0877cf604aa2643bb85b9c69bca4b57 379 Pfam PF02470 MlaD protein 58 134 7.4E-18 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 SUPERFAMILY SSF101874 12 184 1.57E-58 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 Gene3D G3DSA:2.40.128.110 12 184 6.6E-64 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 SMART SM00867 13 182 3.8E-73 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 PANTHER PTHR34406 1 185 1.4E-63 T 16-09-2016 Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 PANTHER PTHR34406:SF1 1 185 1.4E-63 T 16-09-2016 Spa2297_RS23435 60778cba95c379247643cfe12979e94d 185 Pfam PF04264 YceI-like domain 14 180 4.6E-46 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 Gene3D G3DSA:2.40.10.10 270 358 1.3E-31 T 16-09-2016 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 350 1.0E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 292 309 1.0E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 311 334 1.0E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 209 223 1.0E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 271 291 1.0E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 SUPERFAMILY SSF50494 188 366 3.5E-37 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 211 216 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 Gene3D G3DSA:2.40.10.10 183 269 1.6E-26 T 16-09-2016 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 PIRSF PIRSF001134 1 373 1.1E-137 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 Pfam PF00089 Trypsin 210 364 4.2E-15 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 Pfam PF02983 Alpha-lytic protease prodomain 109 163 5.1E-14 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 Gene3D G3DSA:3.30.300.50 40 107 1.4E-6 T 16-09-2016 Spa2297_RS29950 d323e1dacd371f942c74fe8dc7fa96fa 449 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 320 331 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 2.6E-138 T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 PANTHER PTHR11624 358 695 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 SMART SM00861 371 555 2.1E-61 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 SUPERFAMILY SSF52518 5 341 4.02E-104 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 PANTHER PTHR11624 12 331 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Gene3D G3DSA:3.40.50.970 351 564 2.1E-72 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 SUPERFAMILY SSF52922 560 691 6.15E-42 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Gene3D G3DSA:3.40.50.920 565 690 3.2E-48 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 16-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Gene3D G3DSA:3.40.50.970 12 341 1.8E-111 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 688 8.8E-240 T 16-09-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Pfam PF02780 Transketolase, C-terminal domain 576 682 2.0E-11 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 SUPERFAMILY SSF52518 358 556 3.57E-63 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 PANTHER PTHR11624:SF1 12 331 0.0 T 16-09-2016 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 PANTHER PTHR11624:SF1 358 695 0.0 T 16-09-2016 Spa2297_RS07800 aaf363620d566223502cea5d17826ce2 695 Pfam PF02779 Transketolase, pyrimidine binding domain 370 533 7.1E-43 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 5.1E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 SUPERFAMILY SSF46785 11 83 3.77E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 PANTHER PTHR11751 117 465 2.0E-82 T 16-09-2016 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.2E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.2E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 Gene3D G3DSA:3.90.1150.10 326 458 1.4E-17 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 SMART SM00345 21 80 8.6E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 Pfam PF00155 Aminotransferase class I and II 140 435 1.3E-18 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 SUPERFAMILY SSF53383 105 459 7.11E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 Gene3D G3DSA:3.40.640.10 140 325 3.1E-35 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 Gene3D G3DSA:1.10.10.10 9 81 5.2E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23980 fa41f3a9eb39249da501e3997519fcce 471 PANTHER PTHR11751:SF10 117 465 2.0E-82 T 16-09-2016 Spa2297_RS30120 166741f136e457dcd6e12096c9e8a687 368 SUPERFAMILY SSF81606 161 360 2.28E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30120 166741f136e457dcd6e12096c9e8a687 368 SMART SM00331 146 362 4.0E-21 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30120 166741f136e457dcd6e12096c9e8a687 368 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 174 360 5.0E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30120 166741f136e457dcd6e12096c9e8a687 368 PANTHER PTHR21021 77 368 3.6E-41 T 16-09-2016 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 SUPERFAMILY SSF53756 509 712 7.01E-14 T 16-09-2016 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 Gene3D G3DSA:3.90.550.10 1 201 1.5E-50 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 PANTHER PTHR22916 1 394 1.7E-175 T 16-09-2016 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 Pfam PF00535 Glycosyl transferase family 2 5 112 1.5E-36 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 PANTHER PTHR22916:SF3 1 394 1.7E-175 T 16-09-2016 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 PANTHER PTHR22916 410 509 1.7E-175 T 16-09-2016 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 349 713 4.2E-129 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 SUPERFAMILY SSF53448 2 215 2.99E-53 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS10940 18b2a431719dc18ba0a3ebc0e53372d5 744 PANTHER PTHR22916:SF3 410 509 1.7E-175 T 16-09-2016 Spa2297_RS06005 086e5ef7969c915bebdcbd6ae3cd7328 391 Gene3D G3DSA:3.20.20.190 58 382 2.7E-89 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS06005 086e5ef7969c915bebdcbd6ae3cd7328 391 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 63 380 6.5E-45 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS06005 086e5ef7969c915bebdcbd6ae3cd7328 391 PANTHER PTHR23344 58 386 6.3E-110 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS06005 086e5ef7969c915bebdcbd6ae3cd7328 391 SUPERFAMILY SSF51695 57 381 4.97E-77 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS06005 086e5ef7969c915bebdcbd6ae3cd7328 391 PANTHER PTHR23344:SF7 58 386 6.3E-110 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF51011 542 617 5.2E-8 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF51445 1167 1709 1.83E-123 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:2.60.40.1180 538 618 4.2E-12 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357 1286 1451 1.0E-214 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357 977 1038 1.0E-214 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357:SF99 1470 1666 1.0E-214 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357:SF99 1286 1451 1.0E-214 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF00128 Alpha amylase, catalytic domain 105 475 2.9E-102 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357 1059 1259 1.0E-214 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357 1688 1803 1.0E-214 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF51445 251 536 2.78E-94 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF51445 56 193 2.78E-94 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:2.60.40.10 1078 1169 1.9E-15 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF03714 Bacterial pullanase-associated domain 844 935 2.0E-21 T 16-09-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF03714 Bacterial pullanase-associated domain 736 830 1.8E-25 T 16-09-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1077 1155 1.6E-8 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF49452 730 835 1.47E-32 T 16-09-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF81296 943 1067 8.82E-32 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357:SF99 977 1038 1.0E-214 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357:SF99 1059 1259 1.0E-214 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357:SF99 1688 1803 1.0E-214 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 PANTHER PTHR10357 1470 1666 1.0E-214 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF51011 1713 1803 1.58E-26 T 16-09-2016 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:3.20.20.80 1543 1651 5.6E-77 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:3.20.20.80 1184 1487 5.6E-77 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:3.20.20.80 1685 1707 5.6E-77 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF11852 Domain of unknown function (DUF3372) 1655 1802 5.2E-42 T 16-09-2016 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF49452 840 940 3.11E-32 T 16-09-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SUPERFAMILY SSF81296 1077 1173 1.96E-18 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 546 619 4.5E-4 T 16-09-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:3.20.20.80 94 214 2.0E-98 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 Gene3D G3DSA:3.20.20.80 254 537 2.0E-98 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 SMART SM00642 67 527 5.1E-99 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS09295 fe5c7977c7abef3a9b0f203a0428eba0 1805 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 948 1803 0.0 T 16-09-2016 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 Gene3D G3DSA:3.40.50.2300 193 347 4.2E-26 T 16-09-2016 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 PANTHER PTHR30146 22 348 5.2E-89 T 16-09-2016 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 Pfam PF13377 Periplasmic binding protein-like domain 190 348 2.9E-24 T 16-09-2016 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 PANTHER PTHR30146:SF48 22 348 5.2E-89 T 16-09-2016 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 SMART SM00354 22 94 1.1E-19 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 SUPERFAMILY SSF53822 83 347 7.74E-28 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 27 70 3.4E-16 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 Gene3D G3DSA:1.10.260.40 23 76 1.8E-25 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 Gene3D G3DSA:3.40.50.2300 77 192 1.0E-11 T 16-09-2016 Spa2297_RS29165 e7edd44817be09cdc88d7d798db6aa37 348 SUPERFAMILY SSF47413 22 82 1.41E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PRINTS PR00412 Epoxide hydrolase signature 109 127 3.0E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PRINTS PR00412 Epoxide hydrolase signature 180 193 3.0E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PRINTS PR00412 Epoxide hydrolase signature 325 341 3.0E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PRINTS PR00412 Epoxide hydrolase signature 135 150 3.0E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PRINTS PR00412 Epoxide hydrolase signature 357 379 3.0E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 SUPERFAMILY SSF53474 5 380 2.29E-94 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 Gene3D G3DSA:3.40.50.1820 4 385 7.2E-132 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PIRSF PIRSF001112 1 385 1.7E-108 T 16-09-2016 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 Pfam PF06441 Epoxide hydrolase N terminus 6 118 3.4E-31 T 16-09-2016 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PANTHER PTHR21661 5 378 2.7E-95 T 16-09-2016 Spa2297_RS09375 6c5f39e8f883206885d0a692fcea1c5e 390 PANTHER PTHR21661:SF35 5 378 2.7E-95 T 16-09-2016 Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 SUPERFAMILY SSF46785 845 910 5.03E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 SUPERFAMILY SSF52540 517 816 4.02E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 Pfam PF09397 Ftsk gamma domain 848 905 1.3E-21 T 16-09-2016 IPR018541 FtsK gamma domain Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 Gene3D G3DSA:3.40.50.300 518 811 1.2E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 PANTHER PTHR22683:SF41 374 919 1.2E-204 T 16-09-2016 Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 Pfam PF01580 FtsK/SpoIIIE family 546 744 1.7E-55 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 PANTHER PTHR22683 374 919 1.2E-204 T 16-09-2016 Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 SMART SM00382 579 777 5.3E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24320 1e2c5ddc08f0db70352218cf3560a2fe 923 SMART SM00843 844 908 1.6E-28 T 16-09-2016 IPR018541 FtsK gamma domain Spa2297_RS01910 af14f94d55dc5e8e012228364352333d 333 PANTHER PTHR30468:SF5 12 322 2.6E-159 T 16-09-2016 Spa2297_RS01910 af14f94d55dc5e8e012228364352333d 333 PANTHER PTHR30468 12 322 2.6E-159 T 16-09-2016 Spa2297_RS01910 af14f94d55dc5e8e012228364352333d 333 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 27 308 5.7E-54 T 16-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 Spa2297_RS01910 af14f94d55dc5e8e012228364352333d 333 Gene3D G3DSA:3.60.130.10 21 320 4.3E-80 T 16-09-2016 Spa2297_RS01910 af14f94d55dc5e8e012228364352333d 333 SUPERFAMILY SSF51197 26 314 5.95E-78 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 PIRSF PIRSF000098 4 430 1.5E-155 T 16-09-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Gene3D G3DSA:3.40.50.720 2 150 7.8E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Gene3D G3DSA:3.30.70.260 351 420 1.3E-11 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Pfam PF01842 ACT domain 354 416 2.8E-14 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 SUPERFAMILY SSF51735 5 160 7.06E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Gene3D G3DSA:3.30.360.10 151 303 4.0E-55 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 16-09-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 SUPERFAMILY SSF55021 350 422 2.65E-15 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 131 5.0E-20 T 16-09-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 Pfam PF00742 Homoserine dehydrogenase 139 319 8.6E-67 T 16-09-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 PANTHER PTHR21499 1 325 6.8E-132 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 PANTHER PTHR21499:SF2 1 325 6.8E-132 T 16-09-2016 Spa2297_RS22600 584830cac15fd03cb2421e9e4ade95d1 430 SUPERFAMILY SSF55347 139 306 8.5E-53 T 16-09-2016 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 PANTHER PTHR23242 14 1159 0.0 T 16-09-2016 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 181 222 5.4E-15 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 741 780 2.0E-13 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 599 635 1.8E-6 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 42 80 7.7E-8 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 693 733 1.5E-9 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 88 128 6.8E-6 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 Pfam PF03752 Short repeats of unknown function 135 175 1.0E-11 T 16-09-2016 IPR005506 Protein of unknown function DUF312 Spa2297_RS28290 d795282adec8cdfa4f9649b313f41ec7 1159 PANTHER PTHR23242:SF9 14 1159 0.0 T 16-09-2016 Spa2297_RS17565 8d4f8d5335083c063aaf4282cc168014 262 SUPERFAMILY SSF74650 5 259 2.13E-42 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS17565 8d4f8d5335083c063aaf4282cc168014 262 PANTHER PTHR10091:SF5 1 180 7.1E-62 T 16-09-2016 Spa2297_RS17565 8d4f8d5335083c063aaf4282cc168014 262 Gene3D G3DSA:2.70.98.10 7 150 1.3E-13 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS17565 8d4f8d5335083c063aaf4282cc168014 262 PANTHER PTHR10091 1 180 7.1E-62 T 16-09-2016 Spa2297_RS17565 8d4f8d5335083c063aaf4282cc168014 262 Pfam PF01263 Aldose 1-epimerase 6 185 2.5E-18 T 16-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Spa2297_RS17680 77bd789b83c3b2f2f288b52fbcf2297b 173 Pfam PF12028 Protein of unknown function (DUF3515) 44 139 1.3E-6 T 16-09-2016 IPR021903 Protein of unknown function DUF3515 Spa2297_RS04170 a5c42be098bf45ca1916ebf9a811d7c2 199 SUPERFAMILY SSF53335 3 186 9.9E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04170 a5c42be098bf45ca1916ebf9a811d7c2 199 PANTHER PTHR10108 36 143 8.4E-22 T 16-09-2016 Spa2297_RS04170 a5c42be098bf45ca1916ebf9a811d7c2 199 Pfam PF08241 Methyltransferase domain 46 141 6.1E-18 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS04170 a5c42be098bf45ca1916ebf9a811d7c2 199 Gene3D G3DSA:3.40.50.150 6 188 7.2E-31 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04170 a5c42be098bf45ca1916ebf9a811d7c2 199 PANTHER PTHR10108:SF779 36 143 8.4E-22 T 16-09-2016 Spa2297_RS16915 3f3c59d7bd8ecaa032a85c6321d0559f 274 SUPERFAMILY SSF109854 4 159 1.08E-28 T 16-09-2016 Spa2297_RS16915 3f3c59d7bd8ecaa032a85c6321d0559f 274 Pfam PF07398 MDMPI C-terminal domain 168 264 3.6E-10 T 16-09-2016 IPR010872 MDMPI C-terminal Spa2297_RS16915 3f3c59d7bd8ecaa032a85c6321d0559f 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 1.2E-39 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS16915 3f3c59d7bd8ecaa032a85c6321d0559f 274 Gene3D G3DSA:1.20.120.450 12 155 1.6E-7 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS16915 3f3c59d7bd8ecaa032a85c6321d0559f 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 153 1.0E-21 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 Gene3D G3DSA:3.10.350.10 71 121 5.7E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 SUPERFAMILY SSF54106 71 121 6.54E-5 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 SUPERFAMILY SSF51261 155 299 3.92E-43 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 Pfam PF01551 Peptidase family M23 198 295 5.9E-30 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 Pfam PF01476 LysM domain 74 121 9.5E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 Gene3D G3DSA:2.70.70.10 152 300 3.3E-42 T 16-09-2016 Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 SMART SM00257 73 122 2.5E-4 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28220 d64279bc155c8da49b9ffce83a48aa5a 306 PANTHER PTHR21666 141 305 4.5E-40 T 16-09-2016 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 ProSitePatterns PS00455 Putative AMP-binding domain signature. 113 124 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 Gene3D G3DSA:3.30.300.30 334 420 6.7E-14 T 16-09-2016 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 Pfam PF00501 AMP-binding enzyme 15 339 3.4E-26 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 PANTHER PTHR24096 17 418 5.5E-36 T 16-09-2016 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 Gene3D G3DSA:3.40.50.980 15 120 9.3E-5 T 16-09-2016 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 Pfam PF13193 AMP-binding enzyme C-terminal domain 348 415 5.4E-8 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 SUPERFAMILY SSF56801 2 420 7.33E-64 T 16-09-2016 Spa2297_RS26640 ef8faf5f275870b216b58d814540a864 454 Gene3D G3DSA:3.40.50.980 121 265 2.3E-20 T 16-09-2016 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PANTHER PTHR11739:SF4 17 383 6.7E-128 T 16-09-2016 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PANTHER PTHR11739 17 383 6.7E-128 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 Pfam PF00285 Citrate synthase, C-terminal domain 21 377 1.6E-102 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 Gene3D G3DSA:1.10.580.10 27 253 1.2E-61 T 16-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 SUPERFAMILY SSF48256 18 384 4.45E-103 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 ProSitePatterns PS00480 Citrate synthase signature. 275 287 - T 16-09-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PIRSF PIRSF001369 15 391 7.8E-97 T 16-09-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 347 361 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 327 343 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 193 208 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 215 243 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 144 157 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 PRINTS PR00143 Citrate synthase signature 268 288 9.0E-33 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24720 38ab4fe4cea84248eac9cee9736861fc 393 Gene3D G3DSA:1.10.230.10 254 339 4.5E-23 T 16-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 SUPERFAMILY SSF52172 10 138 1.71E-29 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 PANTHER PTHR26402:SF137 11 210 4.5E-100 T 16-09-2016 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.1E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 Gene3D G3DSA:3.40.50.2300 9 152 3.6E-34 T 16-09-2016 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.8E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.8E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.8E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 SMART SM00448 11 124 2.5E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 Pfam PF00072 Response regulator receiver domain 13 124 2.9E-22 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 PANTHER PTHR26402 11 210 4.5E-100 T 16-09-2016 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 SUPERFAMILY SSF46894 133 210 1.43E-16 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 SMART SM00421 147 204 7.7E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09650 ad24ed3c534c152d569f9d3ff3915843 210 Gene3D G3DSA:1.10.10.10 153 210 5.5E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 Gene3D G3DSA:3.40.50.2300 56 171 3.0E-25 T 16-09-2016 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 SMART SM00354 2 69 7.8E-19 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 SUPERFAMILY SSF47413 5 50 1.59E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 Pfam PF13377 Periplasmic binding protein-like domain 173 331 6.5E-41 T 16-09-2016 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 Gene3D G3DSA:3.40.50.2300 172 332 3.1E-53 T 16-09-2016 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 Gene3D G3DSA:1.10.260.40 5 47 4.9E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 3.6E-13 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 SUPERFAMILY SSF53822 59 332 9.62E-69 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 PANTHER PTHR30146 2 335 1.2E-122 T 16-09-2016 Spa2297_RS28680 eb46c66a220f705905e99d383154a7a0 337 PANTHER PTHR30146:SF4 2 335 1.2E-122 T 16-09-2016 Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 Gene3D G3DSA:3.40.50.150 622 755 1.9E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 Gene3D G3DSA:3.40.50.150 1196 1230 1.9E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 Gene3D G3DSA:3.40.50.150 1289 1351 1.9E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 1219 1225 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 PANTHER PTHR33841 502 561 4.5E-30 T 16-09-2016 Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 PANTHER PTHR33841:SF2 627 781 4.5E-30 T 16-09-2016 Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 PANTHER PTHR33841:SF2 502 561 4.5E-30 T 16-09-2016 Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 1289 1357 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 431 454 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 355 378 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 1207 1234 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 623 777 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 SUPERFAMILY SSF53335 503 552 2.87E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22545 2d6da07c1e1c437c3bff8cb5a1c774a0 1899 PANTHER PTHR33841 627 781 4.5E-30 T 16-09-2016 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SMART SM00220 11 277 8.9E-67 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SUPERFAMILY SSF54184 451 509 4.84E-6 T 16-09-2016 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Pfam PF03793 PASTA domain 384 446 8.0E-11 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Pfam PF03793 PASTA domain 586 647 8.4E-10 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Pfam PF03793 PASTA domain 518 580 1.3E-14 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Pfam PF03793 PASTA domain 451 512 2.9E-17 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SMART SM00740 513 580 1.7E-18 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SMART SM00740 380 446 9.7E-17 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SMART SM00740 581 649 8.4E-11 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SMART SM00740 447 512 5.9E-22 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Pfam PF00069 Protein kinase domain 11 265 9.0E-51 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 PANTHER PTHR24362:SF160 1 313 1.6E-113 T 16-09-2016 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 SUPERFAMILY SSF56112 7 273 3.51E-78 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Gene3D G3DSA:1.10.510.10 98 274 1.6E-49 T 16-09-2016 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 PANTHER PTHR24362 1 313 1.6E-113 T 16-09-2016 Spa2297_RS16720 242e009ff7da9198bfa0c7916a372e46 670 Gene3D G3DSA:3.30.200.20 4 94 7.7E-29 T 16-09-2016 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 Gene3D G3DSA:3.40.50.2000 207 423 2.1E-36 T 16-09-2016 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 PANTHER PTHR12526 5 450 7.5E-261 T 16-09-2016 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 26 449 51.313 T 16-09-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 SUPERFAMILY SSF53756 44 447 4.54E-82 T 16-09-2016 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 Pfam PF00534 Glycosyl transferases group 1 249 422 5.5E-31 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 27 446 2.8E-194 T 16-09-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 Pfam PF13439 Glycosyltransferase Family 4 46 227 6.9E-32 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS15170 a998abbec95f42fdbe05632a85f0a407 457 PANTHER PTHR12526:SF185 5 450 7.5E-261 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 Pfam PF04542 Sigma-70 region 2 118 186 1.7E-10 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PANTHER PTHR30173:SF13 89 281 2.4E-61 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PANTHER PTHR30173 89 281 2.4E-61 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PRINTS PR01217 Proline rich extensin signature 440 452 1.5E-17 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PRINTS PR01217 Proline rich extensin signature 485 497 1.5E-17 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PRINTS PR01217 Proline rich extensin signature 502 523 1.5E-17 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 PRINTS PR01217 Proline rich extensin signature 459 475 1.5E-17 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 Gene3D G3DSA:1.10.10.10 222 282 7.2E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 SUPERFAMILY SSF88946 98 196 3.53E-19 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 SMART SM00776 523 667 1.5E-49 T 16-09-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 SUPERFAMILY SSF49785 545 666 3.95E-29 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 SUPERFAMILY SSF88659 221 281 1.48E-6 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 114 282 1.3E-14 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 Gene3D G3DSA:1.10.1740.10 98 200 7.3E-20 T 16-09-2016 Spa2297_RS15610 84765bba4b6c4b2abd8a7d7a0ad71526 668 Pfam PF08305 NPCBM/NEW2 domain 556 666 3.7E-28 T 16-09-2016 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 PANTHER PTHR18866:SF100 1 590 0.0 T 16-09-2016 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 2.1E-74 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Gene3D G3DSA:3.30.470.20 202 450 2.0E-88 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Gene3D G3DSA:2.40.50.100 520 589 5.1E-21 T 16-09-2016 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 SUPERFAMILY SSF51246 328 447 9.94E-36 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 545 562 - T 16-09-2016 IPR001882 Biotin-binding site Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 SUPERFAMILY SSF56059 114 322 1.13E-58 T 16-09-2016 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 9.9E-44 T 16-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 SUPERFAMILY SSF52440 2 112 2.37E-46 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Gene3D G3DSA:3.40.50.20 2 128 3.4E-49 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Gene3D G3DSA:3.30.1490.20 129 201 6.6E-21 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 SUPERFAMILY SSF51230 519 588 2.62E-18 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Pfam PF02785 Biotin carboxylase C-terminal domain 333 447 2.2E-34 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 SMART SM00878 333 447 1.2E-52 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 PANTHER PTHR18866 1 590 0.0 T 16-09-2016 Spa2297_RS20835 88680cdf527102fc4841e14d46c03b05 590 Pfam PF00364 Biotin-requiring enzyme 522 588 7.4E-16 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS29625 12140f8421fef25b634a98484c6b6701 218 SUPERFAMILY SSF100950 38 208 1.8E-38 T 16-09-2016 Spa2297_RS29625 12140f8421fef25b634a98484c6b6701 218 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 48 208 2.0E-19 T 16-09-2016 IPR003741 LUD domain Spa2297_RS29625 12140f8421fef25b634a98484c6b6701 218 Gene3D G3DSA:3.40.50.10420 39 208 4.7E-56 T 16-09-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain Spa2297_RS29625 12140f8421fef25b634a98484c6b6701 218 PANTHER PTHR32479 3 209 4.7E-47 T 16-09-2016 Spa2297_RS29625 12140f8421fef25b634a98484c6b6701 218 PANTHER PTHR32479:SF11 3 209 4.7E-47 T 16-09-2016 Spa2297_RS18400 c2634fdd04af5155fd6a28f07b780975 513 PANTHER PTHR24421:SF26 26 385 1.8E-63 T 16-09-2016 Spa2297_RS18400 c2634fdd04af5155fd6a28f07b780975 513 PANTHER PTHR24421 26 385 1.8E-63 T 16-09-2016 Spa2297_RS18400 c2634fdd04af5155fd6a28f07b780975 513 SUPERFAMILY SSF55874 285 370 1.84E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18400 c2634fdd04af5155fd6a28f07b780975 513 Pfam PF07730 Histidine kinase 168 233 1.4E-9 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS05660 b341443e527e26b73fdb90294243ba1d 583 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 268 577 3.4E-47 T 16-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like Spa2297_RS05660 b341443e527e26b73fdb90294243ba1d 583 PANTHER PTHR30518:SF2 219 579 1.5E-77 T 16-09-2016 Spa2297_RS05660 b341443e527e26b73fdb90294243ba1d 583 Pfam PF02618 YceG-like family 275 574 1.6E-64 T 16-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like Spa2297_RS05660 b341443e527e26b73fdb90294243ba1d 583 PANTHER PTHR30518 219 579 1.5E-77 T 16-09-2016 Spa2297_RS03365 14a2f7e3f1107402d5b015407896b9fe 159 SUPERFAMILY SSF55811 19 140 2.44E-31 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS03365 14a2f7e3f1107402d5b015407896b9fe 159 Pfam PF00293 NUDIX domain 22 137 2.8E-20 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS03365 14a2f7e3f1107402d5b015407896b9fe 159 PANTHER PTHR22769:SF17 22 134 9.8E-39 T 16-09-2016 Spa2297_RS03365 14a2f7e3f1107402d5b015407896b9fe 159 Gene3D G3DSA:3.90.79.10 7 134 6.4E-30 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS03365 14a2f7e3f1107402d5b015407896b9fe 159 PANTHER PTHR22769 22 134 9.8E-39 T 16-09-2016 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 Gene3D G3DSA:3.20.20.80 134 517 6.0E-139 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PANTHER PTHR22600 213 525 8.6E-229 T 16-09-2016 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 6 133 2.4E-24 T 16-09-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 136 483 4.1E-124 T 16-09-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 Gene3D G3DSA:3.30.379.10 5 133 1.2E-32 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PANTHER PTHR22600:SF21 5 196 8.6E-229 T 16-09-2016 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PANTHER PTHR22600:SF21 213 525 8.6E-229 T 16-09-2016 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 SUPERFAMILY SSF55545 3 135 1.7E-25 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 SUPERFAMILY SSF51445 136 499 1.99E-117 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PANTHER PTHR22600 5 196 8.6E-229 T 16-09-2016 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 447 463 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 230 247 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 303 316 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 281 299 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 87 107 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 159 180 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 465 482 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS12710 eae8b7fe8f07dad050955560cf20ef7c 540 PRINTS PR00738 Glycosyl hydrolase family 20 signature 130 147 9.2E-46 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 PANTHER PTHR10196:SF6 14 483 3.0E-205 T 16-09-2016 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 Gene3D G3DSA:3.30.420.40 14 250 2.9E-24 T 16-09-2016 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 SUPERFAMILY SSF53067 15 250 9.06E-44 T 16-09-2016 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 77 250 1.6E-26 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 446 2.6E-31 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 SUPERFAMILY SSF53067 258 482 3.24E-36 T 16-09-2016 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 Gene3D G3DSA:3.30.420.40 264 478 2.6E-17 T 16-09-2016 Spa2297_RS29640 e2dffcba4f4c9f6242990afb9202092a 490 PANTHER PTHR10196 14 483 3.0E-205 T 16-09-2016 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 861 7.1E-235 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 152.075 T 16-09-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 SUPERFAMILY SSF55186 560 717 2.09E-40 T 16-09-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PANTHER PTHR11777:SF9 1 879 0.0 T 16-09-2016 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 SMART SM00863 661 705 8.0E-17 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PANTHER PTHR11777 1 879 0.0 T 16-09-2016 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 Gene3D G3DSA:3.30.930.10 2 244 1.2E-91 T 16-09-2016 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 SUPERFAMILY SSF101353 249 442 7.72E-54 T 16-09-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 SUPERFAMILY SSF55681 3 248 1.82E-87 T 16-09-2016 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 SUPERFAMILY SSF50447 461 560 2.4E-16 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.2E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.2E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.2E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.2E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.2E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 Pfam PF01411 tRNA synthetases class II (A) 5 563 1.0E-182 T 16-09-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Spa2297_RS28800 d9fd79aec27e088ffa8aef7be3a9bd19 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 661 705 1.3E-14 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS22005 be2c37c69fcf21ee463f9483af6146b9 138 Gene3D G3DSA:1.10.10.10 2 82 2.1E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22005 be2c37c69fcf21ee463f9483af6146b9 138 PANTHER PTHR33202 1 138 9.6E-43 T 16-09-2016 Spa2297_RS22005 be2c37c69fcf21ee463f9483af6146b9 138 SUPERFAMILY SSF46785 3 134 6.73E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22005 be2c37c69fcf21ee463f9483af6146b9 138 PANTHER PTHR33202:SF7 1 138 9.6E-43 T 16-09-2016 Spa2297_RS22005 be2c37c69fcf21ee463f9483af6146b9 138 Pfam PF01475 Ferric uptake regulator family 11 104 7.8E-25 T 16-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 Pfam PF00072 Response regulator receiver domain 8 119 5.0E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 PANTHER PTHR26402:SF583 6 217 3.3E-124 T 16-09-2016 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 Gene3D G3DSA:1.10.10.10 161 216 3.5E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 SUPERFAMILY SSF46894 147 217 1.12E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.0E-20 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 Gene3D G3DSA:3.40.50.2300 4 160 7.1E-39 T 16-09-2016 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 SMART SM00421 153 210 3.6E-27 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 PANTHER PTHR26402 6 217 3.3E-124 T 16-09-2016 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 SUPERFAMILY SSF52172 5 127 4.98E-33 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.8E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.8E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.8E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26125 3448cfe6dd5cd6a5a16210032979f081 218 SMART SM00448 6 119 1.4E-30 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 PANTHER PTHR26402 2 226 5.4E-95 T 16-09-2016 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 Gene3D G3DSA:3.40.50.2300 1 120 1.1E-38 T 16-09-2016 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 Gene3D G3DSA:1.10.10.10 130 226 2.4E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 SMART SM00448 2 112 4.1E-41 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 SUPERFAMILY SSF52172 1 183 9.68E-41 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.1E-23 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 PANTHER PTHR26402:SF603 2 226 5.4E-95 T 16-09-2016 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 SMART SM00862 149 225 1.7E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24880 0e5b58805736fd4431a07e2d52628dc2 227 Pfam PF00072 Response regulator receiver domain 4 112 5.9E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 Gene3D G3DSA:1.10.10.10 129 218 2.0E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 PANTHER PTHR26402:SF151 5 219 4.4E-95 T 16-09-2016 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 SMART SM00448 5 120 2.3E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 PANTHER PTHR26402 5 219 4.4E-95 T 16-09-2016 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.5E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.5E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.5E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 SUPERFAMILY SSF46894 154 218 7.82E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 Pfam PF00072 Response regulator receiver domain 7 119 8.7E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 SUPERFAMILY SSF52172 4 139 2.28E-32 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 7.8E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 Gene3D G3DSA:3.40.50.2300 3 128 1.4E-35 T 16-09-2016 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25960 d3d33f8ba377578e6b542ea3212dd52d 219 SMART SM00421 155 212 9.8E-27 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 2.0E-17 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 SUPERFAMILY SSF100950 85 139 1.72E-30 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 SUPERFAMILY SSF100950 167 246 1.72E-30 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 9.4E-10 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 9.4E-10 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 Gene3D G3DSA:3.40.50.1360 88 227 6.6E-17 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 Gene3D G3DSA:1.10.10.10 11 87 2.7E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 SMART SM01134 80 248 6.0E-64 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 SUPERFAMILY SSF46785 10 66 8.14E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 PANTHER PTHR30363:SF13 6 274 2.3E-104 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 PANTHER PTHR30363 6 274 2.3E-104 T 16-09-2016 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 16-09-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 SMART SM00420 12 64 3.9E-18 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03420 2e080adde146d91a103e7a56887bb2c4 274 Pfam PF00455 DeoR C terminal sensor domain 83 246 1.2E-53 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 SUPERFAMILY SSF52518 8 266 8.95E-82 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Gene3D G3DSA:3.40.50.920 479 606 8.1E-31 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Pfam PF02779 Transketolase, pyrimidine binding domain 304 465 9.0E-38 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 261 9.4E-51 T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 PANTHER PTHR11624 2 611 7.8E-295 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 ProSitePatterns PS00802 Transketolase signature 2. 411 427 - T 16-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Pfam PF02780 Transketolase, C-terminal domain 482 601 4.7E-30 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Gene3D G3DSA:3.40.50.970 301 478 1.3E-55 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 PANTHER PTHR11624:SF2 2 611 7.8E-295 T 16-09-2016 Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 Gene3D G3DSA:3.40.50.970 6 270 1.2E-85 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 SUPERFAMILY SSF52518 294 470 2.06E-52 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 SUPERFAMILY SSF52922 473 604 3.01E-28 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS27050 289ac71478c30f38bd895e68afeb4a28 615 SMART SM00861 305 468 9.3E-45 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 Gene3D G3DSA:1.10.1780.10 95 232 1.1E-34 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 109 156 1.5E-6 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 185 233 1.8E-12 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 PANTHER PTHR11638:SF83 85 229 6.1E-76 T 16-09-2016 Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 SUPERFAMILY SSF81923 96 231 2.75E-24 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18040 a1b11d3524dd683b53a252b4bb91088b 251 PANTHER PTHR11638 85 229 6.1E-76 T 16-09-2016 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 PANTHER PTHR23408 1 532 4.2E-289 T 16-09-2016 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 PANTHER PTHR23408:SF1 1 532 4.2E-289 T 16-09-2016 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 SUPERFAMILY SSF51703 8 526 8.24E-210 T 16-09-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 10 528 3.7E-237 T 16-09-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 Pfam PF01642 Methylmalonyl-CoA mutase 10 524 2.3E-222 T 16-09-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Spa2297_RS20575 1d2647a095598704edd1a3eb3d98026c 532 Gene3D G3DSA:3.20.20.240 10 526 7.6E-227 T 16-09-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Spa2297_RS03645 9256008bc78f61b5c7e9147217c59f3d 179 Pfam PF13673 Acetyltransferase (GNAT) domain 58 151 7.9E-11 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS03645 9256008bc78f61b5c7e9147217c59f3d 179 SUPERFAMILY SSF55729 8 159 3.09E-26 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS03645 9256008bc78f61b5c7e9147217c59f3d 179 Gene3D G3DSA:3.40.630.30 8 158 1.4E-28 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS03645 9256008bc78f61b5c7e9147217c59f3d 179 PANTHER PTHR23091 1 178 1.9E-91 T 16-09-2016 Spa2297_RS03645 9256008bc78f61b5c7e9147217c59f3d 179 PANTHER PTHR23091:SF184 1 178 1.9E-91 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 Pfam PF01014 Uricase 10 142 4.5E-19 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 Pfam PF01014 Uricase 152 292 3.6E-28 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PANTHER PTHR10395 1 169 9.5E-159 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PANTHER PTHR10395:SF15 210 301 9.5E-159 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PIRSF PIRSF000241 1 303 5.5E-98 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 187 297 1.0E-61 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PRINTS PR00093 Uricase signature 12 23 1.1E-16 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PRINTS PR00093 Uricase signature 87 100 1.1E-16 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PRINTS PR00093 Uricase signature 173 185 1.1E-16 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PRINTS PR00093 Uricase signature 157 173 1.1E-16 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PRINTS PR00093 Uricase signature 51 65 1.1E-16 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 Gene3D G3DSA:3.10.270.10 3 301 3.5E-105 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 SUPERFAMILY SSF55620 4 140 1.82E-40 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 SUPERFAMILY SSF55620 144 298 1.39E-53 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PANTHER PTHR10395:SF15 1 169 9.5E-159 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 PANTHER PTHR10395 210 301 9.5E-159 T 16-09-2016 Spa2297_RS26330 698099dcd4944dcd3af3c1ce603f0e54 311 TIGRFAM TIGR03383 urate_oxi: urate oxidase 6 297 4.1E-108 T 16-09-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 SUPERFAMILY SSF69618 15 275 1.57E-57 T 16-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 Pfam PF00486 Transcriptional regulatory protein, C terminal 306 370 3.1E-13 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 Gene3D G3DSA:1.10.10.10 280 371 9.4E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 SMART SM00862 300 370 3.8E-14 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 Pfam PF02602 Uroporphyrinogen-III synthase HemD 27 269 2.9E-40 T 16-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 PANTHER PTHR40082 5 286 8.6E-27 T 16-09-2016 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 Gene3D G3DSA:3.40.50.10090 143 278 8.7E-38 T 16-09-2016 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 Gene3D G3DSA:3.40.50.10090 12 142 1.8E-32 T 16-09-2016 Spa2297_RS12775 b1926ca5ef170c9bf7490a62d86ebd62 384 SUPERFAMILY SSF46894 284 370 1.05E-14 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 SUPERFAMILY SSF88659 190 265 1.48E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 PANTHER PTHR30385 14 270 2.0E-106 T 16-09-2016 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Gene3D G3DSA:1.10.601.10 41 114 3.2E-18 T 16-09-2016 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Pfam PF04545 Sigma-70, region 4 216 263 4.8E-17 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Pfam PF04539 Sigma-70 region 3 127 185 2.4E-6 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Pfam PF04542 Sigma-70 region 2 49 117 1.1E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Gene3D G3DSA:1.10.10.10 214 265 4.8E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 43 266 4.0E-82 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 Gene3D G3DSA:1.10.10.10 117 171 7.0E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 SUPERFAMILY SSF88659 121 196 2.75E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 PANTHER PTHR30385:SF4 14 270 2.0E-106 T 16-09-2016 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 SUPERFAMILY SSF88946 39 117 2.09E-24 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 PRINTS PR00046 Major sigma-70 factor signature 219 231 4.8E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 PRINTS PR00046 Major sigma-70 factor signature 236 251 4.8E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 PRINTS PR00046 Major sigma-70 factor signature 73 86 4.8E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02110 fa54a17c743137cc4dc9c414161b06e0 277 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 264 1.4E-30 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS05145 b9f4da5ac76d2dea734a8e37666ed6d4 178 PANTHER PTHR22769 17 108 1.9E-12 T 16-09-2016 Spa2297_RS05145 b9f4da5ac76d2dea734a8e37666ed6d4 178 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS05145 b9f4da5ac76d2dea734a8e37666ed6d4 178 Gene3D G3DSA:3.90.79.10 19 124 4.8E-17 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS05145 b9f4da5ac76d2dea734a8e37666ed6d4 178 SUPERFAMILY SSF55811 13 177 2.03E-24 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS05145 b9f4da5ac76d2dea734a8e37666ed6d4 178 Pfam PF00293 NUDIX domain 48 154 1.2E-12 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 Pfam PF08281 Sigma-70, region 4 107 158 7.1E-10 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 Gene3D G3DSA:1.10.10.10 107 163 1.6E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 161 2.4E-13 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 Gene3D G3DSA:1.10.1740.10 4 98 1.7E-14 T 16-09-2016 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 Pfam PF04542 Sigma-70 region 2 12 76 1.3E-7 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 PANTHER PTHR30173 3 164 2.4E-22 T 16-09-2016 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 SUPERFAMILY SSF88659 107 162 4.49E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29990 78b559c162fbe86e24cf4452c387b46e 164 SUPERFAMILY SSF88946 3 84 1.1E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 PANTHER PTHR24423 247 572 5.7E-60 T 16-09-2016 Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 PANTHER PTHR24423 62 91 5.7E-60 T 16-09-2016 Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 SUPERFAMILY SSF55874 319 443 3.01E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 PANTHER PTHR24423:SF490 62 91 5.7E-60 T 16-09-2016 Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 PANTHER PTHR24423:SF490 247 572 5.7E-60 T 16-09-2016 Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 Gene3D G3DSA:3.30.565.10 335 444 3.8E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 SMART SM00387 333 444 2.9E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30700 e60b27e22204a16b9b65ff22003a76e0 573 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 442 1.4E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 Pfam PF12833 Helix-turn-helix domain 254 332 5.9E-19 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 SUPERFAMILY SSF46689 233 281 3.33E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 Gene3D G3DSA:1.10.10.60 232 284 1.9E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 Gene3D G3DSA:3.40.50.880 25 213 6.5E-48 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 SUPERFAMILY SSF52317 25 213 6.77E-46 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 SMART SM00342 248 331 2.3E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 PANTHER PTHR11019:SF68 25 339 2.6E-160 T 16-09-2016 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 Pfam PF01965 DJ-1/PfpI family 27 192 1.1E-14 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 PANTHER PTHR11019 25 339 2.6E-160 T 16-09-2016 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 SUPERFAMILY SSF46689 285 335 7.43E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11835 f3de548272e3412a5c5d0e93367344dc 396 Gene3D G3DSA:1.10.10.60 285 335 2.9E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 Gene3D G3DSA:2.60.120.200 353 564 1.1E-47 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 Gene3D G3DSA:2.115.10.20 26 330 1.9E-90 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 PANTHER PTHR22925:SF44 26 564 1.5E-164 T 16-09-2016 Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 SUPERFAMILY SSF75005 27 337 7.71E-92 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 PANTHER PTHR22925 26 564 1.5E-164 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 Pfam PF04616 Glycosyl hydrolases family 43 27 321 6.5E-93 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS00710 6d91a612a0ce84e11ce5a90737340a24 574 SUPERFAMILY SSF49899 353 564 1.86E-46 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 SUPERFAMILY SSF103473 5 185 1.18E-37 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 Gene3D G3DSA:1.20.1250.20 6 184 1.7E-27 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 Gene3D G3DSA:1.20.1250.20 259 464 7.1E-18 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 7.8E-6 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 72 94 7.8E-6 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 7.8E-6 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 7.8E-6 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 SUPERFAMILY SSF103473 200 462 2.22E-25 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PANTHER PTHR23501 1 466 1.2E-115 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 PANTHER PTHR23501:SF76 1 466 1.2E-115 T 16-09-2016 Spa2297_RS23935 fe2a68579e63bdbd56104b7c70a1af7b 478 Pfam PF07690 Major Facilitator Superfamily 13 407 2.3E-43 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 SUPERFAMILY SSF48498 87 193 3.45E-20 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 PANTHER PTHR30055:SF49 8 164 2.8E-65 T 16-09-2016 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 Gene3D G3DSA:1.10.357.10 11 201 6.2E-39 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 SUPERFAMILY SSF46689 10 84 1.5E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 3.6E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS17100 5a684ee9bf74c3d67cc5d909872ee927 231 PANTHER PTHR30055 8 164 2.8E-65 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 SUPERFAMILY SSF53850 89 296 6.29E-35 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.7E-20 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 Gene3D G3DSA:3.40.190.10 89 181 1.5E-14 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 PANTHER PTHR30346:SF2 2 300 7.6E-120 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 PANTHER PTHR30346 2 300 7.6E-120 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 Pfam PF03466 LysR substrate binding domain 89 297 1.9E-36 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 Gene3D G3DSA:3.40.190.10 182 271 2.4E-24 T 16-09-2016 Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 Gene3D G3DSA:1.10.10.10 3 87 3.6E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28330 ad2269e69236fead924d40e8ae10cc05 300 SUPERFAMILY SSF46785 3 112 4.05E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11970 7e221d90c91d7e5676da5612b64b71fd 173 Gene3D G3DSA:2.60.120.10 43 163 1.4E-19 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS11970 7e221d90c91d7e5676da5612b64b71fd 173 SMART SM00835 55 173 0.0094 T 16-09-2016 IPR006045 Cupin 1 GO:0045735 Spa2297_RS11970 7e221d90c91d7e5676da5612b64b71fd 173 SUPERFAMILY SSF51182 29 161 6.79E-24 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS11970 7e221d90c91d7e5676da5612b64b71fd 173 Pfam PF07883 Cupin domain 78 150 2.7E-13 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS00310 15784d575ccb3b3cc1952895f068bb5a 277 PANTHER PTHR21624 5 276 2.4E-104 T 16-09-2016 Spa2297_RS00310 15784d575ccb3b3cc1952895f068bb5a 277 PANTHER PTHR21624:SF2 5 276 2.4E-104 T 16-09-2016 Spa2297_RS00310 15784d575ccb3b3cc1952895f068bb5a 277 Pfam PF04116 Fatty acid hydroxylase superfamily 83 216 6.5E-26 T 16-09-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 Spa2297_RS22325 7bb5c0ddfb2cff911550be92cadea057 232 PANTHER PTHR11558 69 219 1.2E-52 T 16-09-2016 Spa2297_RS22325 7bb5c0ddfb2cff911550be92cadea057 232 PANTHER PTHR11558:SF4 69 219 1.2E-52 T 16-09-2016 Spa2297_RS22325 7bb5c0ddfb2cff911550be92cadea057 232 SUPERFAMILY SSF53335 13 212 1.78E-22 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22325 7bb5c0ddfb2cff911550be92cadea057 232 Gene3D G3DSA:3.40.50.150 71 211 4.7E-21 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 Gene3D G3DSA:3.30.497.10 20 164 2.3E-13 T 16-09-2016 Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 Gene3D G3DSA:3.30.497.10 287 330 2.3E-13 T 16-09-2016 Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 SUPERFAMILY SSF56574 287 388 3.8E-10 T 16-09-2016 IPR023796 Serpin domain Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 SUPERFAMILY SSF56574 19 166 1.09E-10 T 16-09-2016 IPR023796 Serpin domain Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 Pfam PF00079 Serpin (serine protease inhibitor) 23 165 1.8E-8 T 16-09-2016 IPR023796 Serpin domain Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 Pfam PF00079 Serpin (serine protease inhibitor) 307 388 9.6E-6 T 16-09-2016 IPR023796 Serpin domain Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 SMART SM00093 11 388 0.004 T 16-09-2016 IPR023796 Serpin domain Spa2297_RS21490 5a9927b710c36160f19dfe50a8b7984f 400 Gene3D G3DSA:2.30.39.10 331 388 1.2E-7 T 16-09-2016 Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 177 2.5E-99 T 16-09-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 Gene3D G3DSA:1.20.1290.10 1 171 2.2E-57 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 178 86.909 T 16-09-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 97 175 3.6E-16 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 112 160 3.2E-22 T 16-09-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS21295 e2ab6b7b28e791527774e3099325e759 178 SUPERFAMILY SSF69118 3 171 1.29E-49 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 87 113 5.7E-65 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 120 144 5.7E-65 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 197 211 5.7E-65 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 145 169 5.7E-65 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 170 194 5.7E-65 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 Gene3D G3DSA:3.40.390.10 82 209 2.0E-37 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 SUPERFAMILY SSF55486 81 209 9.28E-30 T 16-09-2016 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 PIRSF PIRSF016573 1 227 6.2E-125 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 91 212 4.0E-63 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS01580 5c568d5fac36da6f3a0b8a96bb3a4b7f 227 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 80 212 1.4E-85 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Gene3D G3DSA:2.40.10.10 210 292 9.2E-29 T 16-09-2016 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Pfam PF00089 Trypsin 234 386 1.6E-11 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Pfam PF02983 Alpha-lytic protease prodomain 134 190 2.1E-18 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Gene3D G3DSA:2.10.10.20 415 459 1.5E-17 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 236 250 1.2E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 296 316 1.2E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 334 1.2E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 359 1.2E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 360 374 1.2E-40 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Gene3D G3DSA:2.40.10.10 293 382 1.5E-29 T 16-09-2016 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Pfam PF02839 Carbohydrate binding domain 415 456 9.7E-9 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 SUPERFAMILY SSF51055 415 458 2.88E-12 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 SUPERFAMILY SSF54806 58 118 3.14E-5 T 16-09-2016 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 PIRSF PIRSF001134 3 398 3.8E-152 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 SMART SM00495 413 459 6.4E-11 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 SUPERFAMILY SSF50494 211 390 3.11E-35 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Gene3D G3DSA:3.30.300.50 51 132 1.2E-26 T 16-09-2016 Spa2297_RS29550 a261482804e6ab46def1265d7fd59f89 459 Gene3D G3DSA:3.30.300.50 133 200 3.9E-18 T 16-09-2016 Spa2297_RS13745 a0b44dd7cb6035d9fe6f1b7cbbb29916 253 PANTHER PTHR34857 1 251 1.9E-88 T 16-09-2016 Spa2297_RS13745 a0b44dd7cb6035d9fe6f1b7cbbb29916 253 PANTHER PTHR34857:SF2 1 251 1.9E-88 T 16-09-2016 Spa2297_RS13745 a0b44dd7cb6035d9fe6f1b7cbbb29916 253 Pfam PF02361 Cobalt transport protein 15 218 2.0E-32 T 16-09-2016 IPR003339 ABC/ECF transporter, transmembrane component Spa2297_RS13745 a0b44dd7cb6035d9fe6f1b7cbbb29916 253 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 21 214 1.3E-50 T 16-09-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 Spa2297_RS13610 20489cebd77e410fad3b6b6f59df1b3c 151 Pfam PF13508 Acetyltransferase (GNAT) domain 50 129 3.1E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS13610 20489cebd77e410fad3b6b6f59df1b3c 151 Gene3D G3DSA:3.40.630.30 50 150 1.2E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13610 20489cebd77e410fad3b6b6f59df1b3c 151 SUPERFAMILY SSF55729 46 150 5.82E-22 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:2.40.40.20 616 744 8.8E-28 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:3.40.50.740 325 489 4.4E-46 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:3.40.50.740 61 136 4.4E-46 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:3.40.50.740 527 595 4.4E-46 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Pfam PF00384 Molybdopterin oxidoreductase 59 438 6.1E-32 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 PANTHER PTHR11615:SF125 557 744 7.0E-237 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 PANTHER PTHR11615:SF125 8 523 7.0E-237 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Pfam PF01568 Molydopterin dinucleotide binding domain 618 737 1.7E-21 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:2.20.25.90 7 60 8.7E-13 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 49 1.4E-8 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 SMART SM00926 2 55 1.3E-11 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 Gene3D G3DSA:3.40.228.10 142 324 1.7E-50 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 PANTHER PTHR11615 557 744 7.0E-237 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 PANTHER PTHR11615 8 523 7.0E-237 T 16-09-2016 Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 SUPERFAMILY SSF50692 617 743 6.56E-30 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS06720 7d74197c8f26a57c3ce2128a69d6d69a 759 SUPERFAMILY SSF53706 7 601 1.96E-114 T 16-09-2016 Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 Gene3D G3DSA:3.40.50.1000 198 286 9.0E-33 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 Gene3D G3DSA:3.40.50.1000 38 118 9.0E-33 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 Pfam PF02358 Trehalose-phosphatase 42 245 3.3E-26 T 16-09-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 SUPERFAMILY SSF56784 39 284 4.13E-33 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 38 284 1.1E-27 T 16-09-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 Spa2297_RS14835 97509d16679454c8fe35d0169ffaa9aa 289 PANTHER PTHR10788 42 289 2.2E-23 T 16-09-2016 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 PANTHER PTHR30346:SF6 1 308 6.8E-95 T 16-09-2016 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 Pfam PF03466 LysR substrate binding domain 90 288 5.6E-21 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.2E-19 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 PANTHER PTHR30346 1 308 6.8E-95 T 16-09-2016 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 Gene3D G3DSA:3.40.190.10 85 183 6.2E-11 T 16-09-2016 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 Gene3D G3DSA:1.10.10.10 4 84 1.5E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.1E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.1E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.1E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 Gene3D G3DSA:3.40.190.10 184 261 7.0E-11 T 16-09-2016 Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 SUPERFAMILY SSF46785 3 107 5.44E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01575 396899fbf3798cd3823d12ec776f98a7 328 SUPERFAMILY SSF53850 94 294 1.57E-16 T 16-09-2016 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 Pfam PF12704 MacB-like periplasmic core domain 17 232 8.2E-15 T 16-09-2016 IPR025857 MacB-like periplasmic core domain Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 Pfam PF12704 MacB-like periplasmic core domain 491 677 1.6E-9 T 16-09-2016 IPR025857 MacB-like periplasmic core domain Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 Pfam PF02687 FtsX-like permease family 719 835 5.6E-22 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 Pfam PF02687 FtsX-like permease family 269 389 1.2E-22 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 PANTHER PTHR30489 1 192 0.0 T 16-09-2016 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 PANTHER PTHR30489 241 843 0.0 T 16-09-2016 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 PANTHER PTHR30489:SF9 1 192 0.0 T 16-09-2016 Spa2297_RS13415 997aca5f088544cc8cfe6ed8b48e9709 843 PANTHER PTHR30489:SF9 241 843 0.0 T 16-09-2016 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 5.2E-42 T 16-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 304 2.5E-60 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 SUPERFAMILY SSF56059 83 314 1.56E-57 T 16-09-2016 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 SUPERFAMILY SSF52440 2 113 1.29E-46 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 PANTHER PTHR18866:SF85 1 612 0.0 T 16-09-2016 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 568 585 - T 16-09-2016 IPR001882 Biotin-binding site Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Gene3D G3DSA:3.30.470.20 188 424 1.3E-85 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 SUPERFAMILY SSF51230 533 612 5.63E-19 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 PANTHER PTHR18866 1 612 0.0 T 16-09-2016 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Pfam PF02785 Biotin carboxylase C-terminal domain 316 420 2.0E-28 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Pfam PF00364 Biotin-requiring enzyme 546 610 3.6E-15 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Gene3D G3DSA:3.40.50.20 3 123 9.5E-46 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 268 275 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 SUPERFAMILY SSF51246 311 425 5.76E-33 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 SMART SM00878 316 420 1.7E-43 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Gene3D G3DSA:2.40.50.100 541 612 8.7E-22 T 16-09-2016 Spa2297_RS14500 9ce26798c7d2af9206ac336527782b9d 616 Gene3D G3DSA:3.30.1490.20 130 185 2.5E-19 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS26495 e68ec5dc8bbe8d448de9c8b1ee93c9d1 346 PANTHER PTHR32196:SF22 9 346 6.8E-110 T 16-09-2016 Spa2297_RS26495 e68ec5dc8bbe8d448de9c8b1ee93c9d1 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 331 1.0E-56 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS26495 e68ec5dc8bbe8d448de9c8b1ee93c9d1 346 PANTHER PTHR32196 9 346 6.8E-110 T 16-09-2016 Spa2297_RS29030 1345a9995180ef0da502b9739d443cf0 257 SUPERFAMILY SSF55729 18 225 2.59E-39 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS29030 1345a9995180ef0da502b9739d443cf0 257 Gene3D G3DSA:3.40.630.30 22 221 5.8E-31 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS29030 1345a9995180ef0da502b9739d443cf0 257 PANTHER PTHR37323 1 256 8.8E-98 T 16-09-2016 Spa2297_RS29030 1345a9995180ef0da502b9739d443cf0 257 Pfam PF13444 Acetyltransferase (GNAT) domain 36 137 1.3E-31 T 16-09-2016 Spa2297_RS29030 1345a9995180ef0da502b9739d443cf0 257 PANTHER PTHR37323:SF1 1 256 8.8E-98 T 16-09-2016 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050:SF29 141 251 7.8E-83 T 16-09-2016 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 386 580 1.2E-24 T 16-09-2016 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|UniPathway: UPA00378 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050:SF29 14 119 7.8E-83 T 16-09-2016 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050:SF29 273 372 7.8E-83 T 16-09-2016 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050 14 119 7.8E-83 T 16-09-2016 IPR027005 Glycosyltransferase 39-like Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050 273 372 7.8E-83 T 16-09-2016 IPR027005 Glycosyltransferase 39-like Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 82 308 5.8E-22 T 16-09-2016 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Spa2297_RS13720 a553d2e88453ca09045cc5532340853c 581 PANTHER PTHR10050 141 251 7.8E-83 T 16-09-2016 IPR027005 Glycosyltransferase 39-like Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 301 328 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 202 224 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 96 107 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 142 158 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 329 344 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 350 359 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 159 174 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 284 295 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PRINTS PR00359 B-class P450 signature 359 370 3.7E-55 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 Gene3D G3DSA:1.10.630.10 9 406 2.8E-124 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PANTHER PTHR11712 10 405 1.4E-241 T 16-09-2016 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 SUPERFAMILY SSF48264 12 407 6.02E-93 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 Pfam PF00067 Cytochrome P450 190 379 1.0E-21 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS17645 4d37f1b198b8beed3ee382ded77e2bbe 407 PANTHER PTHR11712:SF233 10 405 1.4E-241 T 16-09-2016 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 Gene3D G3DSA:3.40.50.720 19 115 1.0E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 288 2.7E-50 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 SUPERFAMILY SSF51735 109 288 2.7E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 315 8.1E-8 T 16-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 16-09-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 SUPERFAMILY SSF52283 4 127 1.45E-20 T 16-09-2016 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 Gene3D G3DSA:3.40.50.720 116 289 1.5E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 PANTHER PTHR10996:SF127 6 317 2.7E-128 T 16-09-2016 Spa2297_RS11400 15a2deac7803203836e3d64d6a143859 338 PANTHER PTHR10996 6 317 2.7E-128 T 16-09-2016 Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 PANTHER PTHR23501 16 417 3.1E-30 T 16-09-2016 Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 Gene3D G3DSA:1.20.1250.20 30 194 3.5E-11 T 16-09-2016 Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 Pfam PF07690 Major Facilitator Superfamily 36 412 1.5E-26 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 SUPERFAMILY SSF103473 254 417 2.75E-37 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 SUPERFAMILY SSF103473 30 215 2.75E-37 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00060 0e7623cb5c4b6bc2db1fdb453ba38383 422 Gene3D G3DSA:1.20.1250.20 268 417 1.2E-12 T 16-09-2016 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PANTHER PTHR12383 173 279 1.2E-91 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 82 274 1.7E-43 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PANTHER PTHR12383 18 142 1.2E-91 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PANTHER PTHR12383:SF14 18 142 1.2E-91 T 16-09-2016 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 175 187 7.4E-21 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 96 112 7.4E-21 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 227 246 7.4E-21 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 Gene3D G3DSA:2.10.109.10 227 279 1.6E-40 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 Gene3D G3DSA:2.10.109.10 92 185 1.6E-40 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 Pfam PF00717 Peptidase S24-like 103 200 2.3E-15 T 16-09-2016 IPR019759 Peptidase S24/S26A/S26B Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 ProSitePatterns PS00761 Signal peptidases I signature 3. 232 245 - T 16-09-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 PANTHER PTHR12383:SF14 173 279 1.2E-91 T 16-09-2016 Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 SUPERFAMILY SSF51306 170 279 1.41E-48 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS23770 3d4ab50e7c9c9495fcf8ba6e38c7f6d5 328 SUPERFAMILY SSF51306 95 143 1.41E-48 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS14600 2a70ad688540f918fffb80740b8dab3d 195 PANTHER PTHR35400 1 195 4.7E-34 T 16-09-2016 Spa2297_RS14600 2a70ad688540f918fffb80740b8dab3d 195 Gene3D G3DSA:3.90.1570.10 23 153 5.4E-9 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS14600 2a70ad688540f918fffb80740b8dab3d 195 SUPERFAMILY SSF52980 28 159 8.04E-8 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS14600 2a70ad688540f918fffb80740b8dab3d 195 PANTHER PTHR35400:SF1 1 195 4.7E-34 T 16-09-2016 Spa2297_RS14600 2a70ad688540f918fffb80740b8dab3d 195 Pfam PF05685 Putative restriction endonuclease 26 188 1.1E-21 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Pfam PF13424 Tetratricopeptide repeat 653 720 6.5E-9 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Pfam PF13424 Tetratricopeptide repeat 729 801 1.6E-7 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Pfam PF00931 NB-ARC domain 236 433 7.5E-9 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PANTHER PTHR10098 1 22 2.8E-49 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SUPERFAMILY SSF48452 691 879 2.02E-16 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PRINTS PR00364 Disease resistance protein signature 330 344 1.2E-9 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PRINTS PR00364 Disease resistance protein signature 419 433 1.2E-9 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PRINTS PR00364 Disease resistance protein signature 241 256 1.2E-9 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PANTHER PTHR10098:SF104 1 22 2.8E-49 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PANTHER PTHR10098:SF104 596 944 2.8E-49 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Gene3D G3DSA:3.40.50.300 216 353 1.9E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Gene3D G3DSA:1.25.40.10 651 875 1.3E-35 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 Gene3D G3DSA:1.25.40.10 924 976 1.3E-35 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SUPERFAMILY SSF52540 212 473 1.95E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 PANTHER PTHR10098 596 944 2.8E-49 T 16-09-2016 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 651 684 370.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 851 884 310.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 731 764 130.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 771 804 0.055 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 811 844 58.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS21015 17e4db761799ea71275af6a38aad8265 1069 SMART SM00028 691 724 0.5 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 Gene3D G3DSA:3.30.565.10 330 439 5.5E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 PANTHER PTHR24423 189 493 6.1E-16 T 16-09-2016 Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 439 2.4E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 PANTHER PTHR24423:SF508 189 493 6.1E-16 T 16-09-2016 Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 PANTHER PTHR24423:SF508 63 97 6.1E-16 T 16-09-2016 Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 SMART SM00387 327 441 2.2E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 PANTHER PTHR24423 63 97 6.1E-16 T 16-09-2016 Spa2297_RS29810 8eb2c298f69191d8072ccc31882daf09 564 SUPERFAMILY SSF55874 315 443 7.33E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 PANTHER PTHR18919 1 133 2.3E-186 T 16-09-2016 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 PANTHER PTHR18919 154 406 2.3E-186 T 16-09-2016 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 5.1E-47 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 SUPERFAMILY SSF53901 283 404 2.31E-43 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 1.0E-61 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 PIRSF PIRSF000429 1 406 2.0E-130 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Gene3D G3DSA:3.40.47.10 289 404 2.0E-56 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Gene3D G3DSA:3.40.47.10 171 209 2.0E-56 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 1.4E-139 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Gene3D G3DSA:3.40.47.10 210 288 3.5E-61 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 Gene3D G3DSA:3.40.47.10 4 125 3.5E-61 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 SUPERFAMILY SSF53901 3 282 1.18E-66 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 PANTHER PTHR18919:SF69 1 133 2.3E-186 T 16-09-2016 Spa2297_RS13370 277bb315fa6c1670aa874eead36801e0 406 PANTHER PTHR18919:SF69 154 406 2.3E-186 T 16-09-2016 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 PANTHER PTHR26402:SF511 1 218 2.8E-75 T 16-09-2016 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 SMART SM00448 1 112 5.3E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 SUPERFAMILY SSF52172 1 170 6.4E-36 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 Gene3D G3DSA:1.10.10.10 124 219 9.5E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 SMART SM00862 145 217 3.9E-18 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 Gene3D G3DSA:3.40.50.2300 1 123 6.5E-32 T 16-09-2016 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 4.6E-18 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 PANTHER PTHR26402 1 218 2.8E-75 T 16-09-2016 Spa2297_RS16665 29e0bc0730d63156be8c58b368c010a7 231 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-23 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 PANTHER PTHR11993 20 378 3.9E-179 T 16-09-2016 Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 56 67 - T 16-09-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 Gene3D G3DSA:1.10.645.10 17 371 1.2E-58 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 14 383 40.49 T 16-09-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 134 383 1.3E-66 T 16-09-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 SUPERFAMILY SSF56762 29 382 3.66E-101 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS18240 1fd56cd50b5263547168b79e039e9cf8 383 PANTHER PTHR11993:SF28 20 378 3.9E-179 T 16-09-2016 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 314 6.1E-97 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 16-09-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 9.9E-51 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 340 61.773 T 16-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PANTHER PTHR11735 1 334 3.0E-139 T 16-09-2016 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 Pfam PF00814 Glycoprotease family 27 314 2.4E-98 T 16-09-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 Gene3D G3DSA:3.30.420.40 6 162 2.6E-46 T 16-09-2016 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 321 9.3E-126 T 16-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 SUPERFAMILY SSF53067 6 316 3.02E-39 T 16-09-2016 Spa2297_RS20035 28ce28fb6bc4756f9fc934c8439230dd 365 PANTHER PTHR11735:SF6 1 334 3.0E-139 T 16-09-2016 Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 Gene3D G3DSA:2.40.50.140 3 116 4.5E-26 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 PANTHER PTHR10302 9 156 7.4E-16 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 SUPERFAMILY SSF50249 5 155 6.51E-26 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 PIRSF PIRSF002070 1 155 2.3E-23 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 Pfam PF00436 Single-strand binding protein family 3 103 1.4E-20 T 16-09-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Spa2297_RS11380 bb212ae6cb415d499ea16103f5a9b673 158 Hamap MF_00984 Single-stranded DNA-binding protein. 3 110 23.793 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 5.8E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 5.8E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 Gene3D G3DSA:1.10.10.10 4 72 1.4E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 SUPERFAMILY SSF46785 1 76 1.22E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 SUPERFAMILY SSF48008 78 207 3.14E-29 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 Pfam PF07729 FCD domain 82 204 2.6E-23 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 PANTHER PTHR11751:SF385 12 98 3.4E-36 T 16-09-2016 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 PANTHER PTHR11751 12 98 3.4E-36 T 16-09-2016 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 SMART SM00895 82 206 6.4E-18 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 SMART SM00345 14 72 1.1E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 8.8E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS16905 29f717bce8d5367f412783072c72192c 216 Gene3D G3DSA:1.20.120.530 76 204 1.4E-31 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 Gene3D G3DSA:1.10.10.60 11 65 3.5E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 SUPERFAMILY SSF48498 89 203 1.72E-22 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.4E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 Gene3D G3DSA:1.10.357.10 66 203 1.3E-42 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 SUPERFAMILY SSF46689 14 82 1.08E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 PANTHER PTHR30328 12 198 1.4E-37 T 16-09-2016 Spa2297_RS26555 c4d033ef1cecdd0b91fd0986c8b713f1 216 PANTHER PTHR30328:SF19 12 198 1.4E-37 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 SUPERFAMILY SSF46785 5 87 1.25E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 Gene3D G3DSA:3.40.190.10 177 269 4.0E-4 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 Gene3D G3DSA:1.10.10.10 5 86 4.3E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 Gene3D G3DSA:3.40.190.10 105 176 2.8E-8 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 PANTHER PTHR30346:SF7 4 316 5.5E-85 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 SUPERFAMILY SSF53850 104 297 1.71E-16 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 PANTHER PTHR30346 4 316 5.5E-85 T 16-09-2016 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.9E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.9E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.9E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 Pfam PF03466 LysR substrate binding domain 104 289 1.4E-13 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS01535 5f419d8ab9d2973616d2993541a5801c 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.0E-17 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 320 476 2.9E-28 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 435 454 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 SUPERFAMILY SSF56645 93 329 1.7E-37 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 215 310 1.9E-18 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 PANTHER PTHR10909 16 496 2.3E-220 T 16-09-2016 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 PANTHER PTHR10909:SF289 16 496 2.3E-220 T 16-09-2016 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 Gene3D G3DSA:1.20.140.10 313 480 2.0E-39 T 16-09-2016 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 Gene3D G3DSA:2.40.110.10 215 312 3.1E-21 T 16-09-2016 Spa2297_RS03720 b8c0815d5ff601544df4c81fab763614 581 SUPERFAMILY SSF47203 324 479 5.32E-40 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS23095 a9c7ac3b0d394a24114f06d31c3c8434 219 Gene3D G3DSA:3.40.50.720 1 193 5.4E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23095 a9c7ac3b0d394a24114f06d31c3c8434 219 PANTHER PTHR14239 1 197 4.3E-94 T 16-09-2016 Spa2297_RS23095 a9c7ac3b0d394a24114f06d31c3c8434 219 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 6.2E-23 T 16-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spa2297_RS23095 a9c7ac3b0d394a24114f06d31c3c8434 219 PANTHER PTHR14239:SF11 1 197 4.3E-94 T 16-09-2016 Spa2297_RS23095 a9c7ac3b0d394a24114f06d31c3c8434 219 SUPERFAMILY SSF51735 1 194 1.03E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 286 347 9.0E-17 T 16-09-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 SUPERFAMILY SSF52540 39 269 4.25E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 364 160.109 T 16-09-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Gene3D G3DSA:1.10.8.60 202 274 9.2E-31 T 16-09-2016 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 24 254 1.5E-107 T 16-09-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Gene3D G3DSA:3.40.50.300 39 193 3.8E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 272 345 2.4E-29 T 16-09-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 PANTHER PTHR13779 18 349 9.3E-160 T 16-09-2016 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 43 345 2.8E-133 T 16-09-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 PANTHER PTHR13779:SF25 18 349 9.3E-160 T 16-09-2016 Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 SUPERFAMILY SSF46785 276 349 6.53E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 SMART SM00382 70 201 3.5E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05750 c2ccc0c42ea2e3c8f273e330dc12bc9b 364 Gene3D G3DSA:1.10.10.10 276 346 5.7E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 SMART SM00054 43 71 150.0 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 SMART SM00054 6 34 5.5E-4 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 Gene3D G3DSA:1.10.238.10 3 66 5.2E-16 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 Pfam PF13499 EF-hand domain pair 6 64 1.5E-11 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS23090 b15047f1b9fd377cef104e8a6be2d636 71 SUPERFAMILY SSF47473 4 66 3.21E-17 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 SMART SM01060 7 391 5.2E-279 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PIRSF PIRSF038928 1 482 2.5E-219 T 16-09-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 16-09-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 Pfam PF00199 Catalase 7 388 8.6E-187 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 123 141 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 83 101 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 20 43 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 104 121 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 288 315 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PRINTS PR00067 Catalase signature 320 346 3.1E-67 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 Gene3D G3DSA:2.40.180.10 4 357 8.3E-179 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 SUPERFAMILY SSF56634 5 479 6.02E-205 T 16-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 16-09-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 PANTHER PTHR11465 6 478 4.6E-285 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS22010 a644c7fa894fc428b7ddb0816aadf0cd 483 Pfam PF06628 Catalase-related immune-responsive 417 478 1.9E-20 T 16-09-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Gene3D G3DSA:1.20.58.100 485 603 1.2E-31 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 PANTHER PTHR11632:SF53 13 648 0.0 T 16-09-2016 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 SUPERFAMILY SSF51905 417 480 4.21E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 SUPERFAMILY SSF51905 45 288 4.21E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 SUPERFAMILY SSF56425 272 414 1.64E-34 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Gene3D G3DSA:3.90.700.10 278 407 8.5E-19 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Pfam PF00890 FAD binding domain 47 452 4.1E-62 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Pfam PF02910 Fumarate reductase flavoprotein C-term 514 648 9.2E-35 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Gene3D G3DSA:3.50.50.60 409 461 4.9E-77 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 Gene3D G3DSA:3.50.50.60 37 277 4.9E-77 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 416 438 9.1E-7 T 16-09-2016 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 9.1E-7 T 16-09-2016 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 47 648 0.0 T 16-09-2016 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|UniPathway: UPA00223 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 PANTHER PTHR11632 13 648 0.0 T 16-09-2016 Spa2297_RS29020 f01e27df89d144d7fbc4089db9c270bf 649 SUPERFAMILY SSF46977 505 648 1.11E-39 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS28360 98a7a36ba5509697620a4810fbd0a750 175 Gene3D G3DSA:3.90.79.10 22 168 4.3E-7 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS28360 98a7a36ba5509697620a4810fbd0a750 175 Pfam PF16262 Domain of unknown function (DUF4916) 5 172 1.1E-84 T 16-09-2016 IPR032582 Protein of unknown function DUF4916 Spa2297_RS28360 98a7a36ba5509697620a4810fbd0a750 175 SUPERFAMILY SSF55811 24 151 1.8E-8 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 Gene3D G3DSA:3.40.50.300 1 276 9.9E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 SUPERFAMILY SSF52540 1 64 1.67E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 SUPERFAMILY SSF52540 105 298 1.67E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 PANTHER PTHR13696:SF64 1 284 1.1E-53 T 16-09-2016 Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 PANTHER PTHR13696 1 284 1.1E-53 T 16-09-2016 Spa2297_RS17915 d8f8321e663bbe3118074b55be20f9da 326 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 220 3.1E-13 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS07230 53ddef42db940a0eb5ad3eac483dca08 464 SUPERFAMILY SSF111283 9 457 1.96E-66 T 16-09-2016 Spa2297_RS07230 53ddef42db940a0eb5ad3eac483dca08 464 PANTHER PTHR30624:SF8 1 462 2.9E-183 T 16-09-2016 Spa2297_RS07230 53ddef42db940a0eb5ad3eac483dca08 464 PANTHER PTHR30624 1 462 2.9E-183 T 16-09-2016 Spa2297_RS07230 53ddef42db940a0eb5ad3eac483dca08 464 Pfam PF01523 Putative modulator of DNA gyrase 24 325 2.6E-29 T 16-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS08225 effdf2fe51bcb3331a11b1a394a49eed 210 PANTHER PTHR34387:SF1 1 210 2.4E-56 T 16-09-2016 Spa2297_RS08225 effdf2fe51bcb3331a11b1a394a49eed 210 PANTHER PTHR34387 1 210 2.4E-56 T 16-09-2016 Spa2297_RS08225 effdf2fe51bcb3331a11b1a394a49eed 210 Pfam PF04402 Protein of unknown function (DUF541) 11 203 3.2E-36 T 16-09-2016 IPR007497 Protein of unknown function DUF541 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SUPERFAMILY SSF51735 400 565 1.35E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Pfam PF00107 Zinc-binding dehydrogenase 178 292 3.5E-15 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695:SF269 318 374 2.2E-85 T 16-09-2016 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695:SF269 9 45 2.2E-85 T 16-09-2016 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695:SF269 76 302 2.2E-85 T 16-09-2016 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SUPERFAMILY SSF51735 145 295 5.59E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SUPERFAMILY SSF55347 558 686 3.11E-8 T 16-09-2016 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695 318 374 2.2E-85 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695 9 45 2.2E-85 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Gene3D G3DSA:3.30.360.10 530 720 1.7E-24 T 16-09-2016 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Gene3D G3DSA:3.40.50.720 400 529 3.7E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 403 523 2.7E-20 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Gene3D G3DSA:3.90.180.10 53 171 2.7E-14 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 PANTHER PTHR11695 76 302 2.2E-85 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SMART SM00829 46 363 0.0068 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SUPERFAMILY SSF50129 83 176 1.43E-15 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 SUPERFAMILY SSF50129 5 51 1.43E-15 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31785 1988ff55577c8f123999b703276f30a7 723 Gene3D G3DSA:3.40.50.720 172 286 9.9E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07265 593c0ccb560933d140885db6f9a8f0b4 118 PANTHER PTHR38441:SF1 3 118 3.8E-38 T 16-09-2016 Spa2297_RS07265 593c0ccb560933d140885db6f9a8f0b4 118 Pfam PF04341 Protein of unknown function, DUF485 25 111 6.2E-32 T 16-09-2016 IPR007436 Protein of unknown function DUF485 Spa2297_RS07265 593c0ccb560933d140885db6f9a8f0b4 118 SUPERFAMILY SSF103473 31 98 6.02E-5 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS07265 593c0ccb560933d140885db6f9a8f0b4 118 PANTHER PTHR38441 3 118 3.8E-38 T 16-09-2016 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 Gene3D G3DSA:1.10.10.10 129 222 3.5E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 SUPERFAMILY SSF52172 5 137 8.68E-34 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 SMART SM00421 158 215 2.7E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 PANTHER PTHR26402:SF151 6 219 2.0E-98 T 16-09-2016 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 4.2E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 4.2E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 4.2E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 SMART SM00448 6 119 4.7E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 PANTHER PTHR26402 6 219 2.0E-98 T 16-09-2016 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 6.7E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 Gene3D G3DSA:3.40.50.2300 3 128 3.5E-39 T 16-09-2016 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 Pfam PF00072 Response regulator receiver domain 8 117 1.0E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17640 0f0a1ff1a17a3d33cd6bf334da7a96eb 224 SUPERFAMILY SSF46894 148 221 3.27E-22 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 Gene3D G3DSA:1.20.120.530 85 223 1.8E-37 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 SUPERFAMILY SSF46785 16 86 4.99E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 SMART SM00895 92 214 7.5E-13 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 Gene3D G3DSA:1.10.10.10 19 83 1.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 1.8E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 PANTHER PTHR11751 20 108 5.7E-31 T 16-09-2016 Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 SMART SM00345 24 82 8.2E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 Pfam PF07729 FCD domain 92 213 4.4E-14 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 SUPERFAMILY SSF48008 87 222 1.23E-26 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS05245 b4054e20dd2c653c404038d46f373ae9 231 PANTHER PTHR11751:SF3 20 108 5.7E-31 T 16-09-2016 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 149 172 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 193 214 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 51 71 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 100 116 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 73 89 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 224 248 7.3E-22 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 Pfam PF00459 Inositol monophosphatase family 19 251 9.2E-56 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PANTHER PTHR20854 2 254 2.6E-50 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 SUPERFAMILY SSF56655 23 272 3.4E-54 T 16-09-2016 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 Gene3D G3DSA:3.30.540.10 15 173 1.0E-32 T 16-09-2016 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 100 113 - T 16-09-2016 IPR020583 Inositol monophosphatase, metal-binding site Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 PANTHER PTHR20854:SF4 2 254 2.6E-50 T 16-09-2016 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 227 241 - T 16-09-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Spa2297_RS26830 d66e38357d3b3ee9c04df2a1ecd1bf4e 281 Gene3D G3DSA:3.40.190.80 174 277 3.3E-17 T 16-09-2016 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SUPERFAMILY SSF50998 420 735 1.28E-29 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00220 15 278 8.3E-45 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Gene3D G3DSA:1.10.510.10 70 264 2.2E-38 T 16-09-2016 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Pfam PF00069 Protein kinase domain 15 262 5.1E-36 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SUPERFAMILY SSF56112 9 277 4.18E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Gene3D G3DSA:2.140.10.10 426 685 9.6E-32 T 16-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Gene3D G3DSA:3.30.200.20 11 69 3.1E-14 T 16-09-2016 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 479 513 0.0097 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 698 731 5.6 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 618 647 44.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 578 609 57.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 656 688 0.028 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 SMART SM00564 441 471 3.8 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Pfam PF13360 PQQ-like domain 597 731 1.1E-15 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 Pfam PF13360 PQQ-like domain 425 565 2.3E-10 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 PANTHER PTHR24362:SF247 8 270 2.0E-91 T 16-09-2016 Spa2297_RS18925 4b48d7477b2c6710b1fbfe9103fe419b 763 PANTHER PTHR24362 8 270 2.0E-91 T 16-09-2016 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 PANTHER PTHR26402:SF434 7 198 1.3E-63 T 16-09-2016 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 Pfam PF00072 Response regulator receiver domain 9 120 2.0E-21 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 SMART SM00448 7 120 2.3E-23 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 PIRSF PIRSF006171 5 228 7.8E-70 T 16-09-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 SUPERFAMILY SSF52172 5 132 2.99E-31 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 PANTHER PTHR26402 7 198 1.3E-63 T 16-09-2016 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 Gene3D G3DSA:3.40.50.2300 3 126 2.6E-28 T 16-09-2016 Spa2297_RS22970 602f626bbf77e9ad9ecad2e74e11c504 228 Gene3D G3DSA:1.10.10.10 169 210 1.1E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15035 a9cf06861cb19da83e5f4823b3d0eba8 169 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 1 118 6.2E-42 T 16-09-2016 IPR011748 Uncharacterised protein family, phage tail-like Spa2297_RS15035 a9cf06861cb19da83e5f4823b3d0eba8 169 Pfam PF09684 Phage tail protein (Tail_P2_I) 23 152 2.5E-15 T 16-09-2016 IPR006521 Tail protein I Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 20 279 5.4E-77 T 16-09-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 PANTHER PTHR13600:SF12 17 280 2.4E-64 T 16-09-2016 Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 SUPERFAMILY SSF53335 18 299 5.9E-65 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 PANTHER PTHR13600 17 280 2.4E-64 T 16-09-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 Pfam PF04072 Leucine carboxyl methyltransferase 22 202 3.8E-51 T 16-09-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS31895 94049b77e5f121e2a42b436bb87e95c6 302 Gene3D G3DSA:3.40.50.150 24 217 2.1E-19 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 Gene3D G3DSA:3.40.50.10490 63 233 3.3E-8 T 16-09-2016 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 71 2.1E-13 T 16-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 SUPERFAMILY SSF46689 12 72 6.99E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 SUPERFAMILY SSF53697 96 251 1.13E-11 T 16-09-2016 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 PANTHER PTHR30514:SF3 12 274 3.6E-47 T 16-09-2016 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 PANTHER PTHR30514 12 274 3.6E-47 T 16-09-2016 Spa2297_RS00495 4402fa7bd92878dfc32aecc76e1d19a9 274 Gene3D G3DSA:1.10.10.10 12 62 1.3E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29405 a9f727c5bf4b6a19456ca65410bd6b4d 392 Pfam PF00144 Beta-lactamase 63 381 3.3E-69 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS29405 a9f727c5bf4b6a19456ca65410bd6b4d 392 Gene3D G3DSA:3.40.710.10 48 375 2.4E-76 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS29405 a9f727c5bf4b6a19456ca65410bd6b4d 392 SUPERFAMILY SSF56601 48 366 1.46E-76 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS29405 a9f727c5bf4b6a19456ca65410bd6b4d 392 PANTHER PTHR22935 64 368 5.3E-76 T 16-09-2016 Spa2297_RS29405 a9f727c5bf4b6a19456ca65410bd6b4d 392 PANTHER PTHR22935:SF69 64 368 5.3E-76 T 16-09-2016 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 PANTHER PTHR11908:SF95 390 541 1.7E-88 T 16-09-2016 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 PANTHER PTHR11908 390 541 1.7E-88 T 16-09-2016 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 SUPERFAMILY SSF47741 476 547 2.09E-26 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 Gene3D G3DSA:1.10.150.120 467 548 1.3E-29 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 Gene3D G3DSA:3.10.20.30 394 466 1.1E-24 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 Pfam PF01799 [2Fe-2S] binding domain 465 537 8.4E-24 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 SUPERFAMILY SSF54292 393 469 7.34E-18 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS12700 c75245d0961b588d95ad9a68f1569616 615 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 431 439 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 SUPERFAMILY SSF53807 27 318 4.91E-67 T 16-09-2016 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 Gene3D G3DSA:3.40.50.1980 33 193 1.6E-41 T 16-09-2016 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PANTHER PTHR30477 2 320 5.5E-89 T 16-09-2016 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PANTHER PTHR30477:SF16 2 320 5.5E-89 T 16-09-2016 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00690 Adhesin family signature 37 55 1.6E-19 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00690 Adhesin family signature 81 98 1.6E-19 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00690 Adhesin family signature 201 222 1.6E-19 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00690 Adhesin family signature 283 302 1.6E-19 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00690 Adhesin family signature 256 274 1.6E-19 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 81 100 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 142 161 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 37 58 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 296 314 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 201 218 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 PRINTS PR00691 Adhesin B signature 252 269 3.8E-17 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 315 2.1E-66 T 16-09-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Spa2297_RS28740 d34b946965961c323cecf3f8b79244eb 320 Gene3D G3DSA:3.40.50.1980 194 318 1.3E-32 T 16-09-2016 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 SUPERFAMILY SSF103481 64 155 6.15E-14 T 16-09-2016 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 PANTHER PTHR12715 17 323 9.8E-97 T 16-09-2016 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 PANTHER PTHR12715:SF4 17 323 9.8E-97 T 16-09-2016 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 Pfam PF00892 EamA-like transporter family 27 153 4.6E-17 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 Pfam PF00892 EamA-like transporter family 166 299 4.0E-22 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS06680 2ff0ceae34745cb95c7ba12d35cfc180 325 SUPERFAMILY SSF103481 202 303 3.27E-14 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SUPERFAMILY SSF53706 229 699 5.07E-82 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 16-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SUPERFAMILY SSF50692 724 801 6.56E-7 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:3.30.70.20 159 225 9.2E-4 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 24 674 3.6E-203 T 16-09-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF00384 Molybdopterin oxidoreductase 527 658 2.7E-9 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF00384 Molybdopterin oxidoreductase 295 440 1.3E-11 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:2.40.40.20 737 804 7.6E-6 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615 23 310 0.0 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:2.20.25.90 242 291 1.0E-10 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615:SF166 23 310 0.0 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615:SF166 513 833 0.0 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615:SF166 387 446 0.0 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SUPERFAMILY SSF54292 22 94 3.0E-19 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SUPERFAMILY SSF54862 98 233 3.93E-31 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 16-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:3.40.50.740 404 441 3.5E-45 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:3.40.50.740 295 363 3.5E-45 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:3.40.50.740 560 694 3.5E-45 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 6.0E-16 T 16-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SMART SM00926 238 292 1.4E-6 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF01568 Molydopterin dinucleotide binding domain 747 806 6.9E-7 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Gene3D G3DSA:3.10.20.30 22 76 6.8E-6 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 290 2.4E-5 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 51 68 - T 16-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 94 6.4E-18 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 SMART SM00929 105 145 3.3E-19 T 16-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615 513 833 0.0 T 16-09-2016 Spa2297_RS19225 aae587df9f1e0396cdbfa99f59e7d240 834 PANTHER PTHR11615 387 446 0.0 T 16-09-2016 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 SUPERFAMILY SSF56784 3 231 1.23E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 203 8.1E-19 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PANTHER PTHR12725:SF65 1 231 1.5E-57 T 16-09-2016 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 Gene3D G3DSA:3.40.50.1000 2 228 2.8E-41 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PANTHER PTHR12725 1 231 1.5E-57 T 16-09-2016 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 197 1.1E-13 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.2E-8 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.2E-8 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.2E-8 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS23510 da9d62f6e53be5b4fbd19f8d66e207f5 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.2E-8 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 Gene3D G3DSA:2.60.40.290 36 138 5.7E-37 T 16-09-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PANTHER PTHR34876 164 453 1.3E-97 T 16-09-2016 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 Pfam PF01341 Glycosyl hydrolases family 6 184 527 6.0E-92 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 238 254 - T 16-09-2016 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 Gene3D G3DSA:3.20.20.40 160 578 1.1E-117 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 SUPERFAMILY SSF49384 34 138 3.35E-32 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 SMART SM00637 37 136 1.4E-49 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 Pfam PF00553 Cellulose binding domain 37 136 6.4E-31 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PANTHER PTHR34876:SF4 164 453 1.3E-97 T 16-09-2016 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 SUPERFAMILY SSF51989 165 578 4.45E-101 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PIRSF PIRSF001100 12 578 1.2E-107 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 337 350 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 233 246 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 280 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 440 453 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 377 387 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 183 202 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 504 518 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PRINTS PR00733 Glycosyl hydrolase family 6 signature 481 501 1.2E-38 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PANTHER PTHR34876:SF4 477 576 1.3E-97 T 16-09-2016 Spa2297_RS27255 95e11a1b914c797161193368e8c56c3d 579 PANTHER PTHR34876 477 576 1.3E-97 T 16-09-2016 Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 62 186 4.0E-17 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 SUPERFAMILY SSF56784 2 213 1.68E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 2.3E-26 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 PANTHER PTHR18901:SF9 1 215 1.3E-62 T 16-09-2016 Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 Gene3D G3DSA:3.40.50.1000 1 17 7.6E-41 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 Gene3D G3DSA:3.40.50.1000 89 213 7.6E-41 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 Gene3D G3DSA:1.10.150.240 18 84 9.6E-12 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS18520 0aab4c44097efa45ae0aac1a8d41b74d 215 PANTHER PTHR18901 1 215 1.3E-62 T 16-09-2016 Spa2297_RS26990 3da86d77f1571c56398c358c81fb3213 242 SUPERFAMILY SSF53335 9 158 1.04E-22 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS26990 3da86d77f1571c56398c358c81fb3213 242 Gene3D G3DSA:3.40.50.150 29 159 4.1E-19 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS26990 3da86d77f1571c56398c358c81fb3213 242 Pfam PF13649 Methyltransferase domain 54 146 6.1E-10 T 16-09-2016 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 Pfam PF14716 Helix-hairpin-helix domain 4 67 8.7E-16 T 16-09-2016 IPR010996 DNA polymerase beta-like, N-terminal domain Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 PIRSF PIRSF036978 1 337 1.5E-189 T 16-09-2016 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 SUPERFAMILY SSF89550 100 334 1.26E-47 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 SMART SM00481 101 180 2.1E-18 T 16-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 PANTHER PTHR36928 6 347 4.2E-117 T 16-09-2016 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 SUPERFAMILY SSF47802 3 79 2.09E-13 T 16-09-2016 IPR010996 DNA polymerase beta-like, N-terminal domain Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 Gene3D G3DSA:3.20.20.140 100 334 8.1E-47 T 16-09-2016 Spa2297_RS29760 d6afc17bbc4f8b068cb18b679a262002 348 Gene3D G3DSA:1.10.8.310 4 79 2.7E-11 T 16-09-2016 IPR027420 DNA polymerase beta, N-terminal domain Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 SUPERFAMILY SSF51278 1 102 2.09E-43 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 PANTHER PTHR33569:SF1 1 103 2.9E-60 T 16-09-2016 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 PANTHER PTHR33569 1 103 2.9E-60 T 16-09-2016 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 Pfam PF00699 Urease beta subunit 3 99 2.5E-39 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 Gene3D G3DSA:2.10.150.10 1 102 1.8E-45 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 29.764 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04480 88639f02164d81bfee905c1a64b39b7f 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 1.6E-35 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 PANTHER PTHR30363 1 253 3.5E-96 T 16-09-2016 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 SMART SM00420 6 58 2.3E-13 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.2E-51 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 SUPERFAMILY SSF100950 76 237 2.2E-27 T 16-09-2016 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 Gene3D G3DSA:1.10.10.10 5 76 3.4E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 Gene3D G3DSA:3.40.50.1360 77 216 9.1E-12 T 16-09-2016 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 SUPERFAMILY SSF46785 5 58 1.68E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 PANTHER PTHR30363:SF1 1 253 3.5E-96 T 16-09-2016 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 SMART SM01134 73 234 9.4E-69 T 16-09-2016 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 5.3E-15 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.8E-9 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS13920 f51b0e40494af8fc3f1fb844e2062d43 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.8E-9 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 PANTHER PTHR11751 15 99 2.8E-25 T 16-09-2016 Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 Gene3D G3DSA:1.10.10.10 9 74 4.8E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 SUPERFAMILY SSF46785 10 101 6.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 Gene3D G3DSA:1.20.120.530 77 206 1.0E-33 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 3.2E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 Pfam PF07729 FCD domain 83 201 2.4E-24 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 SMART SM00895 83 202 3.1E-18 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 SMART SM00345 15 73 1.3E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 SUPERFAMILY SSF48008 81 206 1.52E-25 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 7.1E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07545 66f5c58085bfb917b49b4578891e1ac8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 7.1E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 3.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 3.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 SUPERFAMILY SSF46785 30 101 4.86E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 Pfam PF00392 Bacterial regulatory proteins, gntR family 35 94 1.8E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 PANTHER PTHR11751 104 481 3.5E-84 T 16-09-2016 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 PANTHER PTHR11751:SF294 104 481 3.5E-84 T 16-09-2016 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 SMART SM00345 38 97 1.2E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 Gene3D G3DSA:3.90.1150.10 349 480 3.3E-16 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 Gene3D G3DSA:3.40.640.10 134 348 3.0E-43 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 Gene3D G3DSA:1.10.10.10 31 96 1.1E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 SUPERFAMILY SSF53383 119 480 1.29E-71 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS05310 d8d58d91a2324c5a57408b3d0c73376d 500 Pfam PF00155 Aminotransferase class I and II 159 462 8.3E-28 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.326 T 16-09-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 Pfam PF00547 Urease, gamma subunit 1 99 8.7E-47 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 Gene3D G3DSA:3.30.280.10 1 99 7.8E-49 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 SUPERFAMILY SSF54111 1 99 1.83E-45 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 PANTHER PTHR33569:SF1 2 100 3.3E-43 T 16-09-2016 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 PANTHER PTHR33569 2 100 3.3E-43 T 16-09-2016 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 PIRSF PIRSF001223 1 100 2.2E-52 T 16-09-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 1.0E-44 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04485 75c8c3b03b57b7347aebcf324b73a8b6 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.3E-50 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 Gene3D G3DSA:3.40.50.2020 161 280 7.4E-31 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 PANTHER PTHR10210:SF32 2 317 1.0E-124 T 16-09-2016 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 120 3.2E-37 T 16-09-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 PANTHER PTHR10210 2 317 1.0E-124 T 16-09-2016 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 SUPERFAMILY SSF53271 69 304 1.19E-44 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 311 3.3E-19 T 16-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 SMART SM01400 4 120 4.6E-58 T 16-09-2016 Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 Gene3D G3DSA:3.40.50.2020 2 160 9.9E-55 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS29795 a7dac13bf846a54c4c1df5564e725766 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 312 1.6E-90 T 16-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS08875 5d2fafb1b4d217596d4c344e710afb30 425 Pfam PF03734 L,D-transpeptidase catalytic domain 252 373 1.6E-16 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS08875 5d2fafb1b4d217596d4c344e710afb30 425 PANTHER PTHR30582 6 403 5.3E-128 T 16-09-2016 Spa2297_RS08875 5d2fafb1b4d217596d4c344e710afb30 425 SUPERFAMILY SSF141523 248 373 6.28E-29 T 16-09-2016 Spa2297_RS08875 5d2fafb1b4d217596d4c344e710afb30 425 Gene3D G3DSA:2.40.440.10 252 375 1.3E-20 T 16-09-2016 Spa2297_RS08875 5d2fafb1b4d217596d4c344e710afb30 425 PANTHER PTHR30582:SF2 6 403 5.3E-128 T 16-09-2016 Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 SUPERFAMILY SSF53271 3 208 8.92E-64 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 PANTHER PTHR10285 1 199 4.1E-81 T 16-09-2016 Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 Gene3D G3DSA:3.40.50.2020 2 208 5.6E-73 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.78 T 16-09-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 2.6E-64 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS15940 82e755461399878547fb07368e5cffe7 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 3.1E-76 T 16-09-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 Pfam PF00005 ABC transporter 19 156 8.7E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 Gene3D G3DSA:3.40.50.300 1 223 1.9E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 PANTHER PTHR24220:SF523 3 219 2.6E-154 T 16-09-2016 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 SMART SM00382 26 204 2.3E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 PANTHER PTHR24220:SF523 302 365 2.6E-154 T 16-09-2016 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 PANTHER PTHR24220 302 365 2.6E-154 T 16-09-2016 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 PANTHER PTHR24220 3 219 2.6E-154 T 16-09-2016 Spa2297_RS22795 e87ad89213c614581bd0db566bd31487 418 SUPERFAMILY SSF52540 2 219 3.29E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10690 c61f74c696853f6e20a0aac9ef714b19 310 Pfam PF13560 Helix-turn-helix domain 44 100 2.3E-14 T 16-09-2016 Spa2297_RS10690 c61f74c696853f6e20a0aac9ef714b19 310 SMART SM00530 20 97 6.1E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS10690 c61f74c696853f6e20a0aac9ef714b19 310 PANTHER PTHR35010 6 298 6.7E-152 T 16-09-2016 Spa2297_RS10690 c61f74c696853f6e20a0aac9ef714b19 310 PANTHER PTHR35010:SF3 6 298 6.7E-152 T 16-09-2016 Spa2297_RS10690 c61f74c696853f6e20a0aac9ef714b19 310 Gene3D G3DSA:1.10.260.40 19 95 5.3E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 SMART SM00732 4 105 1.9E-31 T 16-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 PANTHER PTHR33317 1 154 7.2E-45 T 16-09-2016 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 137 1.4E-30 T 16-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 Pfam PF03652 Holliday junction resolvase 5 137 5.7E-42 T 16-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 Gene3D G3DSA:3.30.420.140 3 142 2.7E-46 T 16-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 PANTHER PTHR33317:SF1 1 154 7.2E-45 T 16-09-2016 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 SUPERFAMILY SSF53098 4 138 9.1E-35 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS05665 c536ef13deeb93f64a936f1e67666987 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.588 T 16-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 SUPERFAMILY SSF54747 5 75 6.8E-30 T 16-09-2016 IPR020784 Ribosomal protein L11, N-terminal Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 PANTHER PTHR11661 1 144 1.6E-74 T 16-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 Gene3D G3DSA:3.30.1550.10 5 74 2.8E-38 T 16-09-2016 IPR020784 Ribosomal protein L11, N-terminal Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 6.1E-29 T 16-09-2016 IPR020784 Ribosomal protein L11, N-terminal Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 1.3E-25 T 16-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 16-09-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 SMART SM00649 12 143 1.3E-86 T 16-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 7.0E-17 T 16-09-2016 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 4.6E-63 T 16-09-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.34 T 16-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 SUPERFAMILY SSF46906 70 143 3.66E-27 T 16-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19615 15f0f40f4ffd9bce9cc1f9abedf38d8f 144 Gene3D G3DSA:1.10.10.250 75 143 2.4E-32 T 16-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS26460 b29da6eb081f79947af7228ae1dd40f8 425 PANTHER PTHR24421 43 424 7.9E-137 T 16-09-2016 Spa2297_RS26460 b29da6eb081f79947af7228ae1dd40f8 425 Pfam PF07730 Histidine kinase 223 287 4.4E-14 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS26460 b29da6eb081f79947af7228ae1dd40f8 425 PANTHER PTHR24421:SF26 43 424 7.9E-137 T 16-09-2016 Spa2297_RS26460 b29da6eb081f79947af7228ae1dd40f8 425 SUPERFAMILY SSF55874 324 424 1.86E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01085 28fd86f9ee7c3738c39556c661e1f0ff 284 Gene3D G3DSA:3.20.20.190 16 282 1.9E-68 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS01085 28fd86f9ee7c3738c39556c661e1f0ff 284 PANTHER PTHR23344:SF20 35 283 3.7E-71 T 16-09-2016 Spa2297_RS01085 28fd86f9ee7c3738c39556c661e1f0ff 284 SUPERFAMILY SSF51695 34 283 1.78E-68 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS01085 28fd86f9ee7c3738c39556c661e1f0ff 284 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 40 280 6.4E-45 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS01085 28fd86f9ee7c3738c39556c661e1f0ff 284 PANTHER PTHR23344 35 283 3.7E-71 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 SMART SM01012 152 207 3.6E-23 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 PIRSF PIRSF036382 17 214 2.1E-71 T 16-09-2016 IPR008327 Signal transduction response regulator, antiterminator Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 SMART SM00448 25 136 1.5E-38 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 PANTHER PTHR26402 25 170 1.2E-49 T 16-09-2016 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 PANTHER PTHR26402:SF474 25 170 1.2E-49 T 16-09-2016 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 SUPERFAMILY SSF52172 24 207 7.97E-57 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 Pfam PF00072 Response regulator receiver domain 27 136 3.6E-30 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 Gene3D G3DSA:1.10.10.10 154 211 1.6E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 Gene3D G3DSA:3.40.50.2300 25 148 1.3E-38 T 16-09-2016 Spa2297_RS08185 c327ab66faa5845dc7a38266d9da7355 218 Pfam PF03861 ANTAR domain 155 207 1.7E-20 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 Gene3D G3DSA:3.30.950.10 284 403 5.5E-43 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 Gene3D G3DSA:3.40.1010.10 170 283 2.3E-40 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 SUPERFAMILY SSF51735 7 110 8.53E-17 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 PANTHER PTHR21091:SF16 136 399 6.8E-73 T 16-09-2016 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 PANTHER PTHR21091:SF16 12 30 6.8E-73 T 16-09-2016 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 248 281 - T 16-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 Gene3D G3DSA:3.40.50.720 7 113 3.7E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 SUPERFAMILY SSF53790 169 403 2.88E-71 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 170 381 2.6E-48 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 Pfam PF13241 Putative NAD(P)-binding 11 118 1.4E-18 T 16-09-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 PANTHER PTHR21091 136 399 6.8E-73 T 16-09-2016 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 PANTHER PTHR21091 12 30 6.8E-73 T 16-09-2016 Spa2297_RS05945 b9c112e3bb82b268436ff36dcab933df 410 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 170 403 4.5E-84 T 16-09-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 SUPERFAMILY SSF51338 373 434 2.16E-10 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 SUPERFAMILY SSF51338 23 57 2.16E-10 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 PANTHER PTHR11271:SF4 6 449 3.6E-174 T 16-09-2016 IPR010252 Formiminoglutamate deiminase Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 Pfam PF01979 Amidohydrolase family 56 423 3.7E-46 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 Gene3D G3DSA:2.30.40.10 383 427 4.4E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 Gene3D G3DSA:2.30.40.10 21 59 4.4E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 Gene3D G3DSA:3.20.20.140 60 382 6.5E-83 T 16-09-2016 Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 SUPERFAMILY SSF51556 57 372 2.34E-72 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 8 449 3.6E-175 T 16-09-2016 IPR010252 Formiminoglutamate deiminase Spa2297_RS13320 5c6b6f40c3c5878c0bedbd1dcd787698 449 PANTHER PTHR11271 6 449 3.6E-174 T 16-09-2016 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 PANTHER PTHR33751 6 226 2.8E-72 T 16-09-2016 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 122 3.0E-8 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 142 216 4.9E-13 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 PIRSF PIRSF000007 1 263 2.8E-132 T 16-09-2016 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 PANTHER PTHR33751:SF1 6 226 2.8E-72 T 16-09-2016 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 SUPERFAMILY SSF46626 124 217 4.65E-27 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 Gene3D G3DSA:1.10.760.10 48 134 1.2E-17 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 Gene3D G3DSA:1.10.760.10 142 222 1.1E-20 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS08860 fd8606016e246c4885152d176e8b429b 269 SUPERFAMILY SSF46626 13 128 3.73E-18 T 16-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PANTHER PTHR23501:SF69 1 509 1.3E-210 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.1E-6 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 174 198 1.1E-6 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 87 109 1.1E-6 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 1.1E-6 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 Pfam PF07690 Major Facilitator Superfamily 29 420 2.9E-54 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 493 7.5E-75 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 Gene3D G3DSA:1.20.1250.20 25 208 1.7E-30 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 SUPERFAMILY SSF103473 472 500 1.4E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 SUPERFAMILY SSF103473 259 430 1.4E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 SUPERFAMILY SSF103473 23 214 1.4E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 PANTHER PTHR23501 1 509 1.3E-210 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 Gene3D G3DSA:1.20.1250.20 473 500 9.9E-19 T 16-09-2016 Spa2297_RS24605 4c57ecbb8706fc926a95e3a064968450 515 Gene3D G3DSA:1.20.1250.20 281 431 9.9E-19 T 16-09-2016 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 Gene3D G3DSA:3.30.360.10 135 315 1.5E-69 T 16-09-2016 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 PANTHER PTHR10174:SF2 47 336 5.5E-59 T 16-09-2016 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 333 1.7E-126 T 16-09-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 132 319 1.7E-52 T 16-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 SUPERFAMILY SSF51735 2 149 5.72E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 PIRSF PIRSF000148 1 337 1.4E-105 T 16-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 PANTHER PTHR10174 47 336 5.5E-59 T 16-09-2016 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 112 5.1E-29 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 333 32.616 T 16-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 SMART SM00859 2 113 2.2E-38 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 236 250 - T 16-09-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 SUPERFAMILY SSF55347 122 320 1.82E-60 T 16-09-2016 Spa2297_RS11185 20911519d6f8ee0107d61b969ef0ad6f 338 Gene3D G3DSA:3.40.50.720 1 134 9.3E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18805 6595ee62d235da8cb0068c2efea3c182 581 Pfam PF05140 ResB-like family 55 535 6.4E-134 T 16-09-2016 IPR007816 ResB-like domain Spa2297_RS18805 6595ee62d235da8cb0068c2efea3c182 581 PANTHER PTHR31566:SF0 6 567 1.3E-179 T 16-09-2016 Spa2297_RS18805 6595ee62d235da8cb0068c2efea3c182 581 PANTHER PTHR31566 6 567 1.3E-179 T 16-09-2016 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 PANTHER PTHR24221:SF161 4 365 9.4E-85 T 16-09-2016 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 PANTHER PTHR24221:SF161 389 566 9.4E-85 T 16-09-2016 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 Gene3D G3DSA:1.20.1560.10 17 324 1.4E-34 T 16-09-2016 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 SUPERFAMILY SSF52540 348 561 1.47E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 Pfam PF00005 ABC transporter 352 496 1.2E-8 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 SUPERFAMILY SSF90123 16 324 7.46E-39 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 Pfam PF00664 ABC transporter transmembrane region 38 295 6.8E-14 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 Gene3D G3DSA:3.40.50.300 348 560 1.2E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 PANTHER PTHR24221 389 566 9.4E-85 T 16-09-2016 Spa2297_RS31100 9f6e9280dc855d969235f2ae663280f6 566 PANTHER PTHR24221 4 365 9.4E-85 T 16-09-2016 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 2.6E-12 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 2.6E-12 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 2.6E-12 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 2.6E-12 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 Pfam PF13242 HAD-hyrolase-like 156 210 2.2E-7 T 16-09-2016 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PANTHER PTHR12725:SF66 1 227 6.0E-52 T 16-09-2016 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 Gene3D G3DSA:3.40.50.1000 7 224 3.8E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 8 204 1.5E-49 T 16-09-2016 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 9 191 5.2E-33 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 PANTHER PTHR12725 1 227 6.0E-52 T 16-09-2016 Spa2297_RS06060 d585f53a6744654ad0272507a3751c22 230 SUPERFAMILY SSF56784 7 227 2.19E-37 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 Gene3D G3DSA:3.30.420.40 5 206 3.5E-11 T 16-09-2016 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 16-09-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 SUPERFAMILY SSF53067 160 397 5.06E-85 T 16-09-2016 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 16-09-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 Hamap MF_00020 Acetate kinase [ackA]. 1 400 179.145 T 16-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 Gene3D G3DSA:3.30.420.40 207 396 3.7E-80 T 16-09-2016 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PANTHER PTHR21060 2 404 5.7E-210 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 6 17 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 175 188 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 378 390 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 301 314 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 205 226 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PRINTS PR00471 Acetate kinase family signature 323 339 1.9E-45 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PANTHER PTHR21060:SF11 2 404 5.7E-210 T 16-09-2016 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 PIRSF PIRSF000722 2 401 5.7E-146 T 16-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 SUPERFAMILY SSF53067 5 197 5.5E-64 T 16-09-2016 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 TIGRFAM TIGR00016 ackA: acetate kinase 5 397 5.8E-145 T 16-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS22930 00802372b43b5f393ea898bebb091c0d 404 Pfam PF00871 Acetokinase family 6 390 3.2E-151 T 16-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 Spa2297_RS00140 39b985d2d5551f632d86f12df1864bc7 437 PANTHER PTHR32507:SF12 15 411 9.1E-63 T 16-09-2016 Spa2297_RS00140 39b985d2d5551f632d86f12df1864bc7 437 PANTHER PTHR32507 15 411 9.1E-63 T 16-09-2016 Spa2297_RS00140 39b985d2d5551f632d86f12df1864bc7 437 Pfam PF00999 Sodium/hydrogen exchanger family 14 405 3.6E-33 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 PANTHER PTHR24220:SF0 16 237 6.2E-102 T 16-09-2016 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 PANTHER PTHR24220:SF0 309 319 6.2E-102 T 16-09-2016 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 Pfam PF00005 ABC transporter 30 173 6.6E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 22 321 7.0E-121 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 Gene3D G3DSA:3.40.50.300 7 238 1.6E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 SMART SM00382 39 228 5.7E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 Pfam PF13732 Domain of unknown function (DUF4162) 227 319 2.2E-7 T 16-09-2016 IPR025302 Domain of unknown function DUF4162 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 SUPERFAMILY SSF52540 11 239 2.36E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 PANTHER PTHR24220 16 237 6.2E-102 T 16-09-2016 Spa2297_RS09415 6dd2d5fe746d345bfbaa5b8d3dd81c45 341 PANTHER PTHR24220 309 319 6.2E-102 T 16-09-2016 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 PIRSF PIRSF004553 1 187 5.3E-50 T 16-09-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 PANTHER PTHR18895:SF60 1 184 6.5E-39 T 16-09-2016 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 SUPERFAMILY SSF53335 2 183 5.58E-42 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 Gene3D G3DSA:3.40.50.150 1 187 2.1E-57 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 Pfam PF03602 Conserved hypothetical protein 95 2 184 1.2E-53 T 16-09-2016 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 PANTHER PTHR18895 1 184 6.5E-39 T 16-09-2016 Spa2297_RS23620 83e201bf9b486ddc24dc111e49d19d61 195 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 184 6.7E-44 T 16-09-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 PIRSF PIRSF017340 1 170 9.2E-83 T 16-09-2016 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 Gene3D G3DSA:3.90.79.10 3 168 3.8E-54 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 PANTHER PTHR22769 6 133 4.3E-19 T 16-09-2016 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 PANTHER PTHR22769:SF25 6 133 4.3E-19 T 16-09-2016 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 ProSitePatterns PS00893 Nudix box signature. 69 90 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 Pfam PF00293 NUDIX domain 32 147 1.6E-14 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS06585 b4305781637d05c4ac591d94085c899d 178 SUPERFAMILY SSF55811 6 170 2.98E-33 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 SUPERFAMILY SSF54427 177 290 2.54E-14 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 9 291 7.3E-98 T 16-09-2016 IPR014303 RNA polymerase sigma-70, ECF type Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 PANTHER PTHR30173 8 293 6.3E-144 T 16-09-2016 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 165 1.2E-16 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Pfam PF04542 Sigma-70 region 2 10 71 2.1E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Gene3D G3DSA:3.10.450.50 176 290 6.0E-16 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Pfam PF08281 Sigma-70, region 4 112 162 5.4E-12 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 SUPERFAMILY SSF88659 93 166 5.01E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 PANTHER PTHR30173:SF25 8 293 6.3E-144 T 16-09-2016 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Gene3D G3DSA:1.10.1740.10 7 75 4.0E-13 T 16-09-2016 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Gene3D G3DSA:1.10.10.10 106 165 9.5E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 SUPERFAMILY SSF88946 8 86 1.18E-14 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04620 7673b75ff6c6cdedf61360f1d04e98b1 295 Pfam PF12680 SnoaL-like domain 182 249 1.1E-6 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 PANTHER PTHR10996:SF20 2 356 8.9E-165 T 16-09-2016 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 SUPERFAMILY SSF55021 455 526 1.25E-14 T 16-09-2016 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 SUPERFAMILY SSF52283 4 136 6.8E-37 T 16-09-2016 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Gene3D G3DSA:3.30.1330.90 319 446 2.3E-43 T 16-09-2016 IPR029009 Allosteric substrate binding domain Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 SUPERFAMILY SSF51735 103 282 6.81E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Gene3D G3DSA:3.30.70.260 447 524 8.4E-18 T 16-09-2016 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 314 8.1E-34 T 16-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Gene3D G3DSA:3.40.50.720 3 108 3.5E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 16-09-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Pfam PF01842 ACT domain 455 516 5.1E-10 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 282 6.7E-62 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 7 527 1.6E-188 T 16-09-2016 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|UniPathway: UPA00135 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 PANTHER PTHR10996 2 356 8.9E-165 T 16-09-2016 Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 SUPERFAMILY SSF143548 321 450 1.1E-33 T 16-09-2016 IPR029009 Allosteric substrate binding domain Spa2297_RS23345 79e1c8674f23721ddf565df6b1653c3a 529 Gene3D G3DSA:3.40.50.720 109 284 1.4E-68 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 SMART SM00345 8 66 1.0E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 4.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 4.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 PANTHER PTHR11751 24 93 6.7E-19 T 16-09-2016 Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 SUPERFAMILY SSF48008 73 206 2.28E-26 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 Gene3D G3DSA:1.20.120.530 70 206 4.4E-28 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 Gene3D G3DSA:1.10.10.10 4 68 8.9E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 Pfam PF07729 FCD domain 76 199 9.0E-22 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 3.0E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 SMART SM00895 76 200 4.4E-16 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS17300 1465529098ef69c0304c23694bbe5b12 208 SUPERFAMILY SSF46785 6 70 8.07E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 Gene3D G3DSA:3.20.20.80 12 331 1.8E-108 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 152 164 - T 16-09-2016 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PANTHER PTHR23421 8 598 3.4E-242 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 Pfam PF01301 Glycosyl hydrolases family 35 16 327 1.3E-106 T 16-09-2016 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PIRSF PIRSF006336 2 595 2.8E-196 T 16-09-2016 IPR026283 Beta-galactosidase 1-like GO:0004565 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 532 548 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 19 36 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 40 58 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 95 114 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 299 315 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 272 287 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 236 251 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PRINTS PR00742 Glycosyl hydrolase family 35 signature 150 165 5.4E-49 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 PANTHER PTHR23421:SF13 8 598 3.4E-242 T 16-09-2016 Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 Gene3D G3DSA:2.60.120.260 450 578 3.6E-25 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 SUPERFAMILY SSF49785 447 583 8.5E-20 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS01275 e8550cbf15d5b78e1f1ae15d4873ee94 599 SUPERFAMILY SSF51445 10 329 1.92E-95 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Gene3D G3DSA:3.40.50.970 239 330 1.1E-58 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Gene3D G3DSA:3.40.50.970 18 194 1.1E-58 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 617 2.6E-186 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 SUPERFAMILY SSF52922 499 619 1.57E-27 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 PANTHER PTHR11624:SF20 17 211 7.0E-257 T 16-09-2016 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 PANTHER PTHR11624:SF20 238 632 7.0E-257 T 16-09-2016 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Gene3D G3DSA:3.40.50.970 331 478 1.4E-27 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 2.5E-106 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 16-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 PANTHER PTHR11624 17 211 7.0E-257 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 PANTHER PTHR11624 238 632 7.0E-257 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 8.4E-35 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Pfam PF02780 Transketolase, C-terminal domain 500 612 1.2E-29 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 SUPERFAMILY SSF52518 294 477 3.37E-49 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 SMART SM00861 315 479 2.1E-48 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 SUPERFAMILY SSF52518 2 345 6.1E-71 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Gene3D G3DSA:3.40.50.920 490 619 5.4E-31 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS25280 12d96a339f1004a00d5262e70cb2dff2 642 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 41.129 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 Gene3D G3DSA:3.10.580.10 4 119 4.6E-29 T 16-09-2016 Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 Pfam PF00571 CBS domain 5 55 5.9E-11 T 16-09-2016 IPR000644 CBS domain Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 Pfam PF00571 CBS domain 70 119 6.9E-10 T 16-09-2016 IPR000644 CBS domain Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 SUPERFAMILY SSF54631 4 122 1.39E-29 T 16-09-2016 Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 SMART SM00116 12 59 4.4E-8 T 16-09-2016 IPR000644 CBS domain Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 SMART SM00116 77 124 5.3E-6 T 16-09-2016 IPR000644 CBS domain Spa2297_RS27140 3e83a694826d8a6db9b6caf3bf83e240 143 PANTHER PTHR11911 2 119 6.6E-24 T 16-09-2016 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 4.0E-70 T 16-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 Gene3D G3DSA:3.40.50.700 24 149 5.7E-34 T 16-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.452 T 16-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 16-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.1E-24 T 16-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 PANTHER PTHR11995 4 155 1.7E-87 T 16-09-2016 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 PANTHER PTHR11995:SF2 4 155 1.7E-87 T 16-09-2016 Spa2297_RS19200 da40d6cef94b58dae666ce7869a2426a 184 SUPERFAMILY SSF56770 9 154 1.07E-65 T 16-09-2016 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 28 384 4.6E-127 T 16-09-2016 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 UniPathway: UPA00060 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Gene3D G3DSA:3.50.50.60 342 399 3.1E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Gene3D G3DSA:3.50.50.60 19 102 3.1E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Gene3D G3DSA:3.50.50.60 170 232 3.1E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Gene3D G3DSA:3.30.9.10 103 169 1.5E-5 T 16-09-2016 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 SUPERFAMILY SSF54373 248 340 3.53E-21 T 16-09-2016 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 PANTHER PTHR13847:SF180 12 402 3.7E-132 T 16-09-2016 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Pfam PF01266 FAD dependent oxidoreductase 27 379 1.1E-64 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 SUPERFAMILY SSF51905 26 247 1.04E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 SUPERFAMILY SSF51905 342 400 1.04E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 Gene3D G3DSA:3.30.9.10 233 340 1.2E-16 T 16-09-2016 Spa2297_RS08645 5d3f2efb6554d888ab04dbd7d1f37733 409 PANTHER PTHR13847 12 402 3.7E-132 T 16-09-2016 Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 9 214 4.1E-79 T 16-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 SMART SM00986 52 211 5.6E-32 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 Pfam PF03167 Uracil DNA glycosylase superfamily 57 208 1.1E-23 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 Gene3D G3DSA:3.40.470.10 6 223 5.1E-94 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 SMART SM00987 52 211 5.6E-32 T 16-09-2016 Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 PANTHER PTHR11264 5 225 3.2E-130 T 16-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 222 40.624 T 16-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 SUPERFAMILY SSF52141 6 222 6.73E-89 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04920 0fe0ce55d7dbc5f3e83a763fb7111748 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 16-09-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Spa2297_RS26010 d600d229b74be7623d4a5ece947de800 172 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 38 129 2.3E-18 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS26010 d600d229b74be7623d4a5ece947de800 172 Pfam PF04075 Domain of unknown function (DUF385) 37 116 4.1E-11 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PIRSF PIRSF001134 2 279 1.2E-94 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 Gene3D G3DSA:2.40.10.10 177 266 1.3E-29 T 16-09-2016 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 Gene3D G3DSA:3.30.300.50 29 92 5.1E-8 T 16-09-2016 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 244 258 7.5E-48 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 200 217 7.5E-48 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 179 199 7.5E-48 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 220 243 7.5E-48 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 125 139 7.5E-48 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 Pfam PF02983 Alpha-lytic protease prodomain 27 81 7.5E-12 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 229 240 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 Gene3D G3DSA:2.40.10.10 98 176 1.0E-25 T 16-09-2016 Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 SUPERFAMILY SSF50494 105 272 4.38E-36 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS25920 0493774dc7a7d88e960d1f8532237af2 279 Pfam PF00089 Trypsin 152 270 2.2E-5 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 Gene3D G3DSA:3.40.50.2300 14 206 8.6E-33 T 16-09-2016 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 SUPERFAMILY SSF53822 14 338 4.42E-44 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 Pfam PF13458 Periplasmic binding protein 14 340 8.0E-34 T 16-09-2016 IPR028081 Leucine-binding protein domain Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 304 319 5.8E-5 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 57 75 5.8E-5 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 5.8E-5 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 PANTHER PTHR30483:SF6 14 357 1.4E-57 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS31250 ee4c463add644f22a7711fd5d8bfeeb6 367 PANTHER PTHR30483 14 357 1.4E-57 T 16-09-2016 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 SUPERFAMILY SSF52374 38 229 3.75E-51 T 16-09-2016 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 Gene3D G3DSA:3.40.50.620 39 230 5.2E-65 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 42 101 1.6E-9 T 16-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 39 229 30.647 T 16-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 Pfam PF01467 Cytidylyltransferase-like 43 203 4.9E-29 T 16-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 43 228 2.0E-53 T 16-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS10890 2e3563689381347eb83ef4fbdb068c42 231 PANTHER PTHR12039 39 231 3.7E-56 T 16-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Gene3D G3DSA:1.10.10.10 180 226 5.2E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SUPERFAMILY SSF54909 240 320 8.85E-8 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Gene3D G3DSA:1.10.10.10 12 59 9.3E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 PANTHER PTHR30154 4 172 1.1E-22 T 16-09-2016 Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SUPERFAMILY SSF46785 181 240 2.17E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Pfam PF01037 Lrp/AsnC ligand binding domain 248 317 8.0E-6 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Pfam PF01037 Lrp/AsnC ligand binding domain 79 147 6.4E-11 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Gene3D G3DSA:3.30.70.920 78 147 1.5E-12 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SUPERFAMILY SSF46785 13 65 1.5E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SUPERFAMILY SSF54909 73 149 1.34E-9 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Gene3D G3DSA:3.30.70.920 235 321 3.4E-7 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Pfam PF13404 AsnC-type helix-turn-helix domain 13 52 2.9E-9 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 Pfam PF13404 AsnC-type helix-turn-helix domain 182 221 8.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SMART SM00344 181 284 3.3E-4 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS02470 2e0d232c745da3dba9266453a64bbe9b 342 SMART SM00344 13 117 7.2E-6 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Gene3D G3DSA:3.90.182.10 69 210 8.8E-29 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Pfam PF06439 Domain of Unknown Function (DUF1080) 807 998 2.8E-34 T 16-09-2016 IPR010496 Domain of unknown function DUF1080 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 SUPERFAMILY SSF63829 234 413 4.71E-12 T 16-09-2016 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 SUPERFAMILY SSF63829 487 550 4.71E-12 T 16-09-2016 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 PANTHER PTHR33546 450 1000 2.6E-185 T 16-09-2016 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 SUPERFAMILY SSF49785 672 805 1.7E-23 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 SUPERFAMILY SSF56988 85 204 2.09E-14 T 16-09-2016 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 PANTHER PTHR33546:SF1 450 1000 2.6E-185 T 16-09-2016 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Pfam PF16990 Carbohydrate binding module (family 35) 675 805 2.9E-14 T 16-09-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Gene3D G3DSA:2.120.10.30 297 412 1.0E-8 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Gene3D G3DSA:2.120.10.30 483 531 1.0E-8 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Gene3D G3DSA:2.120.10.30 622 662 1.0E-8 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Pfam PF07691 PA14 domain 43 180 1.6E-27 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 Gene3D G3DSA:2.60.120.260 675 804 2.1E-26 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS31035 df0d958d21887087799aba2cbd83e929 1001 SMART SM00758 42 183 2.8E-37 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 SUPERFAMILY SSF46689 266 316 1.3E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 SUPERFAMILY SSF46689 215 263 1.25E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 PANTHER PTHR11019 4 320 2.1E-150 T 16-09-2016 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 Gene3D G3DSA:1.10.10.60 269 316 1.1E-9 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 SUPERFAMILY SSF52317 4 195 2.89E-44 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 Pfam PF12833 Helix-turn-helix domain 235 313 9.3E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 Gene3D G3DSA:3.40.50.880 4 221 6.9E-47 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 SMART SM00342 229 312 5.8E-25 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 PANTHER PTHR11019:SF68 4 320 2.1E-150 T 16-09-2016 Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 Pfam PF01965 DJ-1/PfpI family 8 174 1.6E-13 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS22100 693f3594c0b13577cd356e4a3b5a1fd7 322 Gene3D G3DSA:1.10.10.60 222 266 3.7E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 SUPERFAMILY SSF52121 11 156 2.75E-55 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.723 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 Gene3D G3DSA:3.40.50.960 13 157 2.9E-58 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 PANTHER PTHR21058 3 161 1.6E-62 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 1.6E-51 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05420 e251c33aca67fc68bc9417f70ce6fd11 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 1.3E-42 T 16-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 SUPERFAMILY SSF53850 97 305 1.17E-26 T 16-09-2016 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 Pfam PF03466 LysR substrate binding domain 96 301 5.6E-27 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 Gene3D G3DSA:3.40.190.10 185 273 1.0E-10 T 16-09-2016 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 1.0E-19 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 PANTHER PTHR30346:SF7 11 303 1.1E-61 T 16-09-2016 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 SUPERFAMILY SSF46785 10 91 8.3E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 Gene3D G3DSA:1.10.10.10 10 88 2.3E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 PANTHER PTHR30346 11 303 1.1E-61 T 16-09-2016 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 Gene3D G3DSA:3.40.190.10 89 184 9.8E-14 T 16-09-2016 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.3E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.3E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS03335 d5f3cbf6b0a9212cb46986a460fcf566 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.3E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS30390 ec503f9e0aab601b0355e39061798c26 69 PANTHER PTHR35344 1 66 5.7E-36 T 16-09-2016 Spa2297_RS30390 ec503f9e0aab601b0355e39061798c26 69 Pfam PF00741 Gas vesicle protein 16 52 8.8E-14 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS30390 ec503f9e0aab601b0355e39061798c26 69 PANTHER PTHR35344:SF2 1 66 5.7E-36 T 16-09-2016 Spa2297_RS28765 0f5c47017dae44565153e225e800ec5f 244 SUPERFAMILY SSF51735 1 204 3.66E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28765 0f5c47017dae44565153e225e800ec5f 244 PANTHER PTHR14194:SF69 1 232 2.3E-90 T 16-09-2016 Spa2297_RS28765 0f5c47017dae44565153e225e800ec5f 244 Pfam PF13460 NAD(P)H-binding 22 136 9.6E-7 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28765 0f5c47017dae44565153e225e800ec5f 244 Gene3D G3DSA:3.40.50.720 1 200 5.6E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28765 0f5c47017dae44565153e225e800ec5f 244 PANTHER PTHR14194 1 232 2.3E-90 T 16-09-2016 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 252 368 1.2E-48 T 16-09-2016 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44|UniPathway: UPA00157 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 3.8E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PRINTS PR00111 Alpha/beta hydrolase fold signature 193 207 3.8E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 3.8E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.8E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 Gene3D G3DSA:3.40.50.1820 5 248 1.3E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 SUPERFAMILY SSF53474 6 247 1.23E-60 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 Pfam PF08386 TAP-like protein 190 244 9.1E-5 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 Pfam PF00561 alpha/beta hydrolase fold 15 133 4.0E-14 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 Pfam PF02627 Carboxymuconolactone decarboxylase family 281 362 5.4E-25 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PANTHER PTHR10992:SF818 4 249 1.7E-67 T 16-09-2016 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 PANTHER PTHR10992 4 249 1.7E-67 T 16-09-2016 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 Gene3D G3DSA:1.20.1290.10 270 371 1.2E-24 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 4 247 2.9E-84 T 16-09-2016 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185|UniPathway: UPA00157 Spa2297_RS27870 045807ce7f95258f888fbd0fe289bc8a 373 SUPERFAMILY SSF69118 249 369 2.09E-33 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS31725 f3e1a3a1d5d369b60761439af4bc9788 419 Gene3D G3DSA:3.40.50.2000 251 314 6.6E-4 T 16-09-2016 Spa2297_RS31725 f3e1a3a1d5d369b60761439af4bc9788 419 PANTHER PTHR36836 13 410 9.0E-224 T 16-09-2016 Spa2297_RS31725 f3e1a3a1d5d369b60761439af4bc9788 419 PANTHER PTHR36836:SF2 13 410 9.0E-224 T 16-09-2016 Spa2297_RS31725 f3e1a3a1d5d369b60761439af4bc9788 419 Pfam PF04230 Polysaccharide pyruvyl transferase 27 335 6.2E-23 T 16-09-2016 IPR007345 Polysaccharide pyruvyl transferase Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 Gene3D G3DSA:3.40.50.150 286 446 1.4E-21 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 Pfam PF08242 Methyltransferase domain 303 388 1.4E-11 T 16-09-2016 IPR013217 Methyltransferase type 12 Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 PANTHER PTHR21404 1 476 1.4E-110 T 16-09-2016 IPR026610 3'-RNA ribose 2'-O-methyltransferase, Hen1 GO:0001510|GO:0008171|GO:0008173 Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 477 6.1E-205 T 16-09-2016 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 249 1.1E-111 T 16-09-2016 IPR024740 Hen1, N-terminal Spa2297_RS25095 e25dbacc3ec563744845c45c193e384a 492 SUPERFAMILY SSF53335 280 446 1.51E-21 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 Gene3D G3DSA:1.10.12.10 209 267 2.2E-18 T 16-09-2016 IPR014748 Crontonase, C-terminal Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 16-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 PANTHER PTHR11941 3 264 1.9E-111 T 16-09-2016 Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 Gene3D G3DSA:3.90.226.10 3 207 7.4E-60 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 PANTHER PTHR11941:SF76 3 264 1.9E-111 T 16-09-2016 Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 SUPERFAMILY SSF52096 2 266 2.49E-78 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS21690 65676789958f9af88e67fd9571160408 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 265 9.6E-58 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS19315 e4037a0734c8e3482fc2ef05393b3ecc 394 Gene3D G3DSA:3.40.640.10 7 161 3.0E-25 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS19315 e4037a0734c8e3482fc2ef05393b3ecc 394 SUPERFAMILY SSF53383 8 280 6.28E-28 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS19315 e4037a0734c8e3482fc2ef05393b3ecc 394 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 8 160 7.3E-20 T 16-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spa2297_RS25840 5291fa73d1578fd6980e621cc91a8214 150 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 73 3.9E-7 T 16-09-2016 IPR027379 Cardiolipin synthase N-terminal Spa2297_RS25840 5291fa73d1578fd6980e621cc91a8214 150 Pfam PF09851 Short C-terminal domain 111 137 7.7E-7 T 16-09-2016 IPR018649 SHOCT domain Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 SUPERFAMILY SSF52317 160 378 1.72E-50 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 SMART SM01097 11 141 3.9E-89 T 16-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 379 46.022 T 16-09-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 139 1.3E-52 T 16-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 Gene3D G3DSA:3.50.30.20 12 145 5.0E-59 T 16-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 SUPERFAMILY SSF52021 12 145 2.88E-56 T 16-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 376 5.8E-135 T 16-09-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 Pfam PF00117 Glutamine amidotransferase class-I 193 373 4.2E-37 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00097 Anthranilate synthase component II signature 259 270 1.8E-5 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00097 Anthranilate synthase component II signature 350 363 1.8E-5 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.8E-5 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 275 1.0E-29 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 293 1.0E-29 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 1.0E-29 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 1.0E-29 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 301 312 1.0E-29 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 8.0E-11 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 8.0E-11 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 259 270 8.0E-11 T 16-09-2016 Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 Gene3D G3DSA:3.40.50.880 162 378 5.4E-62 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS05590 5703422094f9fa1752a9442fef4144a1 380 PANTHER PTHR11405 11 380 4.3E-204 T 16-09-2016 Spa2297_RS19400 c59edbe837b47b1b6d3c12f37b2a5666 324 PANTHER PTHR12147 38 271 1.6E-67 T 16-09-2016 Spa2297_RS19400 c59edbe837b47b1b6d3c12f37b2a5666 324 PANTHER PTHR12147 289 323 1.6E-67 T 16-09-2016 Spa2297_RS19400 c59edbe837b47b1b6d3c12f37b2a5666 324 Gene3D G3DSA:3.40.630.10 55 323 2.7E-80 T 16-09-2016 Spa2297_RS19400 c59edbe837b47b1b6d3c12f37b2a5666 324 SUPERFAMILY SSF53187 57 323 2.54E-73 T 16-09-2016 Spa2297_RS19400 c59edbe837b47b1b6d3c12f37b2a5666 324 Pfam PF04389 Peptidase family M28 113 318 3.7E-51 T 16-09-2016 IPR007484 Peptidase M28 Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 Pfam PF00005 ABC transporter 20 158 6.1E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 SUPERFAMILY SSF52540 4 220 3.52E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 Gene3D G3DSA:3.40.50.300 3 228 2.0E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 PANTHER PTHR24220:SF523 5 226 9.2E-111 T 16-09-2016 Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 SMART SM00382 28 206 1.2E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS04595 62f5b09b7a1e6e03ddc5c60a75f3e8ee 306 PANTHER PTHR24220 5 226 9.2E-111 T 16-09-2016 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 17 88 5.0E-32 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 15 93 25.098 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 ProSitePatterns PS00056 Ribosomal protein S17 signature. 68 80 - T 16-09-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 PANTHER PTHR10744 17 94 3.5E-38 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 17 88 1.2E-34 T 16-09-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 SUPERFAMILY SSF50249 17 94 1.5E-30 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 Pfam PF00366 Ribosomal protein S17 22 89 6.0E-31 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 Gene3D G3DSA:2.40.50.140 17 94 1.2E-34 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 PRINTS PR00973 Ribosomal protein S17 family signature 36 59 1.2E-11 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 PRINTS PR00973 Ribosomal protein S17 family signature 78 85 1.2E-11 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19840 d4ca980e163a18c847a4a1d2a2149011 95 PRINTS PR00973 Ribosomal protein S17 family signature 68 78 1.2E-11 T 16-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 PANTHER PTHR23090 1 580 4.9E-165 T 16-09-2016 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 TIGRFAM TIGR00552 nadE: NAD+ synthetase 311 559 2.1E-54 T 16-09-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 PIRSF PIRSF006630 1 584 9.9E-214 T 16-09-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|UniPathway: UPA00253 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 SUPERFAMILY SSF56317 3 261 1.7E-55 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 Pfam PF00795 Carbon-nitrogen hydrolase 5 261 1.5E-23 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 Gene3D G3DSA:3.60.110.10 3 260 6.1E-54 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 Gene3D G3DSA:3.40.50.620 300 564 4.7E-73 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 SUPERFAMILY SSF52402 299 564 1.7E-72 T 16-09-2016 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 16-09-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 Spa2297_RS09350 d70d60df523578832e9ae6bc17a40648 584 Pfam PF02540 NAD synthase 309 556 6.0E-67 T 16-09-2016 IPR022310 NAD/GMP synthase Spa2297_RS12325 223dd953b7d49091ef344fe7607f98ed 157 SUPERFAMILY SSF69118 15 151 6.94E-39 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS12325 223dd953b7d49091ef344fe7607f98ed 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 3.5E-22 T 16-09-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS12325 223dd953b7d49091ef344fe7607f98ed 157 Gene3D G3DSA:1.20.1290.10 15 152 1.8E-47 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS12325 223dd953b7d49091ef344fe7607f98ed 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 95 1.1E-19 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS05025 2469e1994955de38f9c13be9ff300c74 505 SUPERFAMILY SSF55931 37 465 2.84E-47 T 16-09-2016 Spa2297_RS05025 2469e1994955de38f9c13be9ff300c74 505 PIRSF PIRSF012666 1 498 1.0E-232 T 16-09-2016 IPR016602 Uncharacterised conserved protein UCP012666 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 193 499 1.2E-116 T 16-09-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PRINTS PR00481 Cytosol aminopeptidase signature 377 392 5.8E-49 T 16-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PRINTS PR00481 Cytosol aminopeptidase signature 349 369 5.8E-49 T 16-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PRINTS PR00481 Cytosol aminopeptidase signature 290 311 5.8E-49 T 16-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PRINTS PR00481 Cytosol aminopeptidase signature 327 348 5.8E-49 T 16-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PRINTS PR00481 Cytosol aminopeptidase signature 268 285 5.8E-49 T 16-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 SUPERFAMILY SSF53187 187 501 1.8E-114 T 16-09-2016 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 SUPERFAMILY SSF52949 17 153 5.41E-25 T 16-09-2016 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 507 34.207 T 16-09-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PANTHER PTHR11963:SF13 14 503 8.3E-202 T 16-09-2016 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 Gene3D G3DSA:3.40.630.10 186 503 2.7E-131 T 16-09-2016 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 Gene3D G3DSA:3.40.220.10 16 185 3.4E-37 T 16-09-2016 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 21 149 1.1E-26 T 16-09-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 353 360 - T 16-09-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Spa2297_RS09005 f819088e1aaa1a54ac504bbd22bd2f71 511 PANTHER PTHR11963 14 503 8.3E-202 T 16-09-2016 Spa2297_RS10800 bd34f38d2ca72dd75354a32d12def8fb 371 SUPERFAMILY SSF53098 6 198 2.35E-30 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS10800 bd34f38d2ca72dd75354a32d12def8fb 371 SUPERFAMILY SSF53098 236 364 2.35E-30 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS10800 bd34f38d2ca72dd75354a32d12def8fb 371 Pfam PF13546 DDE superfamily endonuclease 1 241 3.3E-82 T 16-09-2016 Spa2297_RS10800 bd34f38d2ca72dd75354a32d12def8fb 371 PANTHER PTHR33627:SF1 1 363 1.1E-84 T 16-09-2016 Spa2297_RS10800 bd34f38d2ca72dd75354a32d12def8fb 371 PANTHER PTHR33627 1 363 1.1E-84 T 16-09-2016 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 Gene3D G3DSA:3.40.140.10 1 142 2.5E-59 T 16-09-2016 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 85 - T 16-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 PANTHER PTHR11079 1 143 5.5E-45 T 16-09-2016 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 SUPERFAMILY SSF53927 1 141 4.18E-52 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 Pfam PF14437 MafB19-like deaminase 1 141 3.1E-32 T 16-09-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Spa2297_RS15955 5965b2688bc0dd48e98563bd2e3a5599 143 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 143 47.891 T 16-09-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 SUPERFAMILY SSF51905 3 182 5.71E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 SUPERFAMILY SSF51905 214 336 5.71E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PANTHER PTHR22912 77 144 6.4E-26 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PANTHER PTHR22912 5 60 6.4E-26 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PANTHER PTHR22912 161 348 6.4E-26 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 1.1E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 1.5E-12 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.5E-12 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.5E-12 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.5E-12 T 16-09-2016 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 Gene3D G3DSA:3.50.50.60 3 172 2.4E-20 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27045 28ec7e72a9c17d21793346cff6765b46 618 Gene3D G3DSA:3.50.50.60 173 346 1.1E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 PIRSF PIRSF036525 1 256 6.8E-118 T 16-09-2016 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376|UniPathway: UPA00148 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 Gene3D G3DSA:3.40.1010.10 2 145 8.5E-35 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 PANTHER PTHR10882:SF1 3 33 2.0E-41 T 16-09-2016 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 PANTHER PTHR10882:SF1 57 176 2.0E-41 T 16-09-2016 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 SUPERFAMILY SSF53790 2 252 2.76E-31 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 Gene3D G3DSA:3.30.950.10 146 253 5.2E-47 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 252 1.9E-113 T 16-09-2016 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376|UniPathway: UPA00148 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 225 2.2E-26 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 PANTHER PTHR10882 3 33 2.0E-41 T 16-09-2016 Spa2297_RS28415 5404cc4fe3a7b3f553bbb8321c554358 256 PANTHER PTHR10882 57 176 2.0E-41 T 16-09-2016 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 ProSitePatterns PS00177 DNA topoisomerase II signature. 484 492 - T 16-09-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Gene3D G3DSA:3.40.50.670 466 686 2.3E-76 T 16-09-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 326 339 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 566 583 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 52 67 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 482 496 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 586 598 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 548 564 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 87 100 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 130 144 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR00418 DNA topoisomerase II family signature 637 653 8.3E-62 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PANTHER PTHR10169:SF20 1 706 2.2E-228 T 16-09-2016 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Gene3D G3DSA:3.30.230.10 259 452 3.8E-49 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 184 2.3E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 23 33 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 436 456 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 532 541 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 658 670 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 674 690 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 214 229 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 229 242 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 259 281 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PRINTS PR01159 DNA gyrase subunit B signature 370 386 2.2E-33 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Pfam PF00204 DNA gyrase B 260 452 1.3E-55 T 16-09-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 SUPERFAMILY SSF54211 260 452 3.03E-39 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 SUPERFAMILY SSF56719 456 698 4.45E-77 T 16-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 636 693 7.3E-25 T 16-09-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 SMART SM00387 48 208 3.8E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 SMART SM00433 52 698 2.3E-294 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 SUPERFAMILY SSF55874 23 241 2.1E-58 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Pfam PF01751 Toprim domain 481 588 1.0E-15 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 PANTHER PTHR10169 1 706 2.2E-228 T 16-09-2016 Spa2297_RS24670 932c4080915ee884fa82932bcfe9b2cb 707 Gene3D G3DSA:3.30.565.10 23 241 3.3E-80 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 Gene3D G3DSA:1.20.1250.20 239 409 1.7E-10 T 16-09-2016 Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 Gene3D G3DSA:1.20.1250.20 39 217 7.7E-29 T 16-09-2016 Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 Pfam PF07690 Major Facilitator Superfamily 42 260 3.9E-28 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 SUPERFAMILY SSF103473 26 410 1.15E-56 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 92 108 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 PANTHER PTHR23501:SF80 24 418 1.1E-169 T 16-09-2016 Spa2297_RS20725 d1f0fbd8b4db09383fda56c5534e7db5 427 PANTHER PTHR23501 24 418 1.1E-169 T 16-09-2016 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 Pfam PF00072 Response regulator receiver domain 4 112 8.8E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 PANTHER PTHR26402 2 226 1.8E-89 T 16-09-2016 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 PANTHER PTHR26402:SF578 2 226 1.8E-89 T 16-09-2016 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 SMART SM00862 150 226 3.8E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 Gene3D G3DSA:1.10.10.10 133 227 2.5E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 SMART SM00448 2 112 9.2E-41 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 SUPERFAMILY SSF46894 129 226 1.47E-26 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 9.1E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 SUPERFAMILY SSF52172 1 119 6.4E-41 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS02510 233dac92018477e8360c5566f8c98a1d 229 Gene3D G3DSA:3.40.50.2300 1 119 3.7E-41 T 16-09-2016 Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 Gene3D G3DSA:3.40.50.300 17 246 2.0E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 SUPERFAMILY SSF52540 19 242 6.18E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 PANTHER PTHR24220:SF445 22 252 2.3E-149 T 16-09-2016 Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 SMART SM00382 45 237 8.4E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 Pfam PF00005 ABC transporter 37 180 4.8E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS18480 2b148de15da101e8258c6c078f08a81c 271 PANTHER PTHR24220 22 252 2.3E-149 T 16-09-2016 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 SUPERFAMILY SSF51366 27 273 9.42E-62 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 PIRSF PIRSF029271 4 303 4.9E-150 T 16-09-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 51.807 T 16-09-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 5.2E-142 T 16-09-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 ProSitePatterns PS01235 PdxS/SNZ family signature. 214 232 - T 16-09-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 Gene3D G3DSA:3.20.20.70 33 169 5.4E-46 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 Gene3D G3DSA:3.20.20.70 201 287 5.4E-46 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 Pfam PF01680 SOR/SNZ family 16 221 4.2E-106 T 16-09-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05775 ecf4f822855cc4cfe09717e3bd1a0977 303 PANTHER PTHR31829 11 303 8.4E-218 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 55.329 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Gene3D G3DSA:2.30.40.10 72 142 5.6E-13 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Pfam PF01979 Amidohydrolase family 132 457 5.8E-64 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PANTHER PTHR22642 327 507 2.9E-228 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 1.7E-52 T 16-09-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 573 4.7E-263 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 SUPERFAMILY SSF51338 428 483 2.68E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PANTHER PTHR22642:SF7 327 507 2.9E-228 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PANTHER PTHR22642:SF7 44 303 2.9E-228 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 16-09-2016 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 SUPERFAMILY SSF51556 136 438 9.36E-183 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 SUPERFAMILY SSF51556 487 573 9.36E-183 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PANTHER PTHR22642 44 303 2.9E-228 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 16-09-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 SUPERFAMILY SSF51338 2 183 3.73E-57 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 4.2E-32 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 4.2E-32 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 4.2E-32 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 4.2E-32 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Gene3D G3DSA:3.20.20.140 143 435 2.1E-189 T 16-09-2016 Spa2297_RS04475 8805223dd97d7e9c5bc9aff58dcc79e1 573 Gene3D G3DSA:3.20.20.140 494 571 2.1E-189 T 16-09-2016 Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SUPERFAMILY SSF49785 189 325 3.9E-17 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SUPERFAMILY SSF51126 708 1093 9.34E-40 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Pfam PF12708 Pectate lyase superfamily protein 728 992 2.0E-8 T 16-09-2016 IPR024535 Pectate lyase superfamily protein Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 1046 1068 15.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 897 919 75.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 955 978 98.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 1073 1096 690.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 864 885 750.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 830 861 8100.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 979 1002 72.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00710 921 943 49.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Gene3D G3DSA:2.60.120.260 187 330 8.7E-21 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SMART SM00231 43 180 1.0E-10 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Pfam PF07705 CARDB 331 430 3.1E-22 T 16-09-2016 IPR011635 CARDB domain Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Pfam PF07705 CARDB 443 543 5.4E-17 T 16-09-2016 IPR011635 CARDB domain Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Gene3D G3DSA:2.160.20.10 708 1112 1.8E-28 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 SUPERFAMILY SSF49785 44 179 1.63E-23 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Pfam PF00754 F5/8 type C domain 200 321 5.8E-9 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Pfam PF00754 F5/8 type C domain 57 174 4.5E-19 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS03175 501b93a1809e7436454fecb02a1a4fe9 1129 Gene3D G3DSA:2.60.120.260 44 179 4.5E-28 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 Pfam PF01037 Lrp/AsnC ligand binding domain 95 159 1.2E-11 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 SUPERFAMILY SSF46785 22 81 1.96E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 SUPERFAMILY SSF54909 84 159 2.68E-13 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 PANTHER PTHR30154 14 165 7.9E-90 T 16-09-2016 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 Gene3D G3DSA:3.30.70.920 74 159 4.4E-20 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 SMART SM00344 22 128 2.2E-24 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 Gene3D G3DSA:1.10.10.10 21 73 8.6E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 22 69 1.5E-14 T 16-09-2016 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 38 1.1E-9 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 1.1E-9 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 1.1E-9 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS16805 cff4f48a4f99172e6d8887e499852c20 166 PANTHER PTHR30154:SF16 14 165 7.9E-90 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 SUPERFAMILY SSF53822 81 339 2.36E-35 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 SMART SM00420 8 60 3.2E-10 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 16-09-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 SUPERFAMILY SSF46785 7 59 5.59E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 Pfam PF13377 Periplasmic binding protein-like domain 192 358 5.5E-33 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 PANTHER PTHR30146:SF29 77 358 4.1E-84 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 PANTHER PTHR30146 77 358 4.1E-84 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 Pfam PF08220 DeoR-like helix-turn-helix domain 8 60 2.2E-12 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 Gene3D G3DSA:3.40.50.2300 81 198 2.8E-18 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 Gene3D G3DSA:3.40.50.2300 199 335 5.0E-28 T 16-09-2016 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 Gene3D G3DSA:1.10.10.10 7 54 7.1E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.9E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS30380 3dc1ab6888a8dc12bcbe8555d191180c 367 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.9E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 SUPERFAMILY SSF46785 26 170 9.58E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PANTHER PTHR33164:SF4 6 173 3.9E-34 T 16-09-2016 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PANTHER PTHR33164 6 173 3.9E-34 T 16-09-2016 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 8.9E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 113 8.9E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 133 8.9E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 147 167 8.9E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 Gene3D G3DSA:1.10.10.10 20 171 8.5E-38 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 SMART SM00347 54 157 7.8E-19 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11215 6054489340ba93b9d14cd29ef3623073 173 Pfam PF12802 MarR family 60 121 5.0E-13 T 16-09-2016 Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 PANTHER PTHR23408 2 312 5.1E-107 T 16-09-2016 Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 Pfam PF03308 ArgK protein 20 280 7.4E-98 T 16-09-2016 Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 Gene3D G3DSA:3.40.50.300 47 251 4.3E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 SUPERFAMILY SSF52540 3 311 5.22E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 1.7E-105 T 16-09-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Spa2297_RS22830 629d79321389275b0610a7079df4eb30 318 PANTHER PTHR23408:SF3 2 312 5.1E-107 T 16-09-2016 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 PANTHER PTHR24362:SF247 1 259 5.8E-85 T 16-09-2016 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 SUPERFAMILY SSF56112 6 293 9.98E-67 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 SMART SM00220 10 264 4.8E-56 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 PANTHER PTHR24362 1 259 5.8E-85 T 16-09-2016 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 Pfam PF00069 Protein kinase domain 10 260 1.7E-45 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 Gene3D G3DSA:1.10.510.10 80 261 1.8E-47 T 16-09-2016 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 Gene3D G3DSA:3.30.200.20 3 79 9.2E-23 T 16-09-2016 Spa2297_RS20150 dec680a6ab5916b6f805f4d10b6c9152 567 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Gene3D G3DSA:1.10.601.10 47 135 1.7E-24 T 16-09-2016 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 PANTHER PTHR30385:SF4 39 291 9.5E-103 T 16-09-2016 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 SUPERFAMILY SSF88946 21 137 7.2E-32 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Gene3D G3DSA:1.10.10.10 234 286 5.4E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 SUPERFAMILY SSF88659 208 288 9.91E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 PANTHER PTHR30385 39 291 9.5E-103 T 16-09-2016 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Pfam PF04545 Sigma-70, region 4 237 286 1.4E-16 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 64 287 2.4E-31 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Pfam PF04539 Sigma-70 region 3 147 207 1.1E-11 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 PRINTS PR00046 Major sigma-70 factor signature 92 105 2.9E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 PRINTS PR00046 Major sigma-70 factor signature 241 253 2.9E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 PRINTS PR00046 Major sigma-70 factor signature 258 273 2.9E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Pfam PF04542 Sigma-70 region 2 68 137 1.8E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 SUPERFAMILY SSF88659 141 216 1.48E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 92 105 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 62 288 7.7E-86 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02295 f80dfe5369a9dc67203e597b7d07356d 295 Gene3D G3DSA:1.10.10.10 136 191 1.1E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 SUPERFAMILY SSF50447 5 212 3.44E-81 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 5.8E-91 T 16-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 Gene3D G3DSA:2.40.30.10 162 211 5.7E-12 T 16-09-2016 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 Gene3D G3DSA:2.40.30.10 7 36 5.7E-12 T 16-09-2016 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 Pfam PF00297 Ribosomal protein L3 98 186 9.4E-15 T 16-09-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 16-09-2016 IPR019926 Ribosomal protein L3, conserved site Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 Gene3D G3DSA:4.10.960.10 80 161 7.9E-33 T 16-09-2016 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 PANTHER PTHR11229 7 212 1.5E-109 T 16-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19795 816a448c385cff972170e66988bacc0d 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 40.333 T 16-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 PANTHER PTHR35561:SF1 1 188 3.9E-47 T 16-09-2016 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 Pfam PF13563 2'-5' RNA ligase superfamily 16 165 7.3E-17 T 16-09-2016 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 170 8.9E-31 T 16-09-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 186 22.208 T 16-09-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 Gene3D G3DSA:3.90.1140.10 1 188 1.2E-49 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 PANTHER PTHR35561 1 188 3.9E-47 T 16-09-2016 Spa2297_RS14595 b84882afd852d34375f67e512df5fd63 190 SUPERFAMILY SSF55144 1 187 4.88E-38 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS18320 d59d583030a2b2e97d2817cae9524b29 169 PANTHER PTHR23091 2 129 8.3E-23 T 16-09-2016 Spa2297_RS18320 d59d583030a2b2e97d2817cae9524b29 169 Gene3D G3DSA:3.40.630.30 4 147 1.6E-31 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS18320 d59d583030a2b2e97d2817cae9524b29 169 SUPERFAMILY SSF55729 2 130 6.08E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS18320 d59d583030a2b2e97d2817cae9524b29 169 PANTHER PTHR23091:SF259 2 129 8.3E-23 T 16-09-2016 Spa2297_RS18320 d59d583030a2b2e97d2817cae9524b29 169 Pfam PF00583 Acetyltransferase (GNAT) family 53 122 6.8E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 PANTHER PTHR19211 315 545 1.2E-304 T 16-09-2016 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 PANTHER PTHR19211 14 293 1.2E-304 T 16-09-2016 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 Pfam PF00005 ABC transporter 368 496 6.0E-14 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 Pfam PF00005 ABC transporter 22 187 2.7E-22 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 SMART SM00382 29 232 1.8E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 SMART SM00382 375 542 2.9E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 PANTHER PTHR19211:SF46 14 293 1.2E-304 T 16-09-2016 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 PANTHER PTHR19211:SF46 315 545 1.2E-304 T 16-09-2016 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 SUPERFAMILY SSF52540 351 545 5.09E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 SUPERFAMILY SSF52540 5 229 4.96E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 Gene3D G3DSA:3.40.50.300 7 281 1.9E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28075 d6507491cbcf89ef80d3f9bbf277f28b 548 Gene3D G3DSA:3.40.50.300 364 545 2.0E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 PANTHER PTHR12110:SF3 1 271 1.6E-94 T 16-09-2016 Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 SUPERFAMILY SSF51658 9 270 3.18E-59 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 Pfam PF01261 Xylose isomerase-like TIM barrel 26 229 2.0E-28 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 Gene3D G3DSA:3.20.20.150 7 271 4.2E-71 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 PIRSF PIRSF006241 4 278 7.0E-87 T 16-09-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 Spa2297_RS26305 7d7b6736124255731847b98085132ed9 279 PANTHER PTHR12110 1 271 1.6E-94 T 16-09-2016 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 PANTHER PTHR31964 1 156 9.3E-33 T 16-09-2016 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 SUPERFAMILY SSF52402 152 286 6.45E-24 T 16-09-2016 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 Gene3D G3DSA:3.40.50.620 148 286 8.5E-24 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 Gene3D G3DSA:3.40.50.620 1 135 3.3E-32 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 PANTHER PTHR31964:SF42 1 156 9.3E-33 T 16-09-2016 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 PRINTS PR01438 Universal stress protein signature 2 20 6.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 PRINTS PR01438 Universal stress protein signature 95 107 6.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 PRINTS PR01438 Universal stress protein signature 113 135 6.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 SUPERFAMILY SSF52402 3 138 1.51E-27 T 16-09-2016 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 Pfam PF00582 Universal stress protein family 156 286 2.1E-17 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS02185 0baf0bf3f06393d2ac6c6a6fc3bad006 288 Pfam PF00582 Universal stress protein family 1 135 8.0E-23 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 1.4E-28 T 16-09-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.344 T 16-09-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 2.6E-155 T 16-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 8.4E-30 T 16-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:3.90.1110.10 171 340 3.5E-69 T 16-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856 654 933 0.0 T 16-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856 10 49 0.0 T 16-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856 71 637 0.0 T 16-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856 957 1129 0.0 T 16-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:3.90.1100.10 571 625 4.5E-145 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:3.90.1100.10 29 169 4.5E-145 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:3.90.1100.10 354 502 4.5E-145 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856:SF20 654 933 0.0 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856:SF20 10 49 0.0 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856:SF20 71 637 0.0 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 PANTHER PTHR20856:SF20 957 1129 0.0 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:2.40.50.100 627 697 2.6E-26 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 16-09-2016 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 1.5E-25 T 16-09-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF04563 RNA polymerase beta subunit 37 409 1.8E-21 T 16-09-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:2.30.150.10 503 568 6.9E-28 T 16-09-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 16-09-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.0E-27 T 16-09-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:2.40.50.150 734 864 4.3E-56 T 16-09-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 16-09-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:2.40.270.10 865 1025 4.0E-75 T 16-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19645 4bbcf5dd4abf84b5ac122e417ace9b54 1161 Gene3D G3DSA:2.40.270.10 698 725 4.0E-75 T 16-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.3E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.3E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 Gene3D G3DSA:1.10.10.60 11 58 8.8E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 158 210 1.0E-6 T 16-09-2016 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 Gene3D G3DSA:1.10.357.10 59 212 3.0E-20 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 PANTHER PTHR30055 1 211 1.5E-22 T 16-09-2016 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 PANTHER PTHR30055:SF76 1 211 1.5E-22 T 16-09-2016 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 SUPERFAMILY SSF46689 6 84 4.74E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31690 551c95dd4a6ee69f9210a91eb745aaf1 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 6.2E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS24575 dc536cc4a84a2b7e7bf69eb42b54fa6e 185 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 6.2E-45 T 16-09-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Spa2297_RS24575 dc536cc4a84a2b7e7bf69eb42b54fa6e 185 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 76.317 T 16-09-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Spa2297_RS24575 dc536cc4a84a2b7e7bf69eb42b54fa6e 185 PANTHER PTHR30455 2 153 1.1E-65 T 16-09-2016 Spa2297_RS24575 dc536cc4a84a2b7e7bf69eb42b54fa6e 185 PANTHER PTHR30455:SF2 2 153 1.1E-65 T 16-09-2016 Spa2297_RS24575 dc536cc4a84a2b7e7bf69eb42b54fa6e 185 Pfam PF03477 ATP cone domain 47 132 2.7E-14 T 16-09-2016 IPR005144 ATP-cone domain Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 103 178 2.6E-26 T 16-09-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 103 351 3.6E-37 T 16-09-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 PANTHER PTHR11943:SF2 25 350 6.6E-117 T 16-09-2016 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 PANTHER PTHR11943 25 350 6.6E-117 T 16-09-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 Gene3D G3DSA:3.30.428.10 64 177 4.3E-34 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 PIRSF PIRSF000808 32 353 3.0E-107 T 16-09-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 Gene3D G3DSA:3.30.428.10 180 351 6.1E-46 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 203 349 2.2E-13 T 16-09-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 SUPERFAMILY SSF54197 183 351 1.02E-31 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 SUPERFAMILY SSF54197 36 179 6.12E-46 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS13655 1f7a735f554c1582a3c621c939785ac7 353 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 16-09-2016 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 SUPERFAMILY SSF53187 11 207 3.43E-63 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 SUPERFAMILY SSF53187 378 463 3.43E-63 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 Pfam PF01546 Peptidase family M20/M25/M40 91 459 5.2E-34 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 Gene3D G3DSA:3.30.70.360 207 369 4.9E-57 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 SUPERFAMILY SSF55031 310 373 8.37E-5 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 PANTHER PTHR11014 1 276 3.1E-225 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 PANTHER PTHR11014 294 467 3.1E-225 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 Pfam PF07687 Peptidase dimerisation domain 204 363 1.8E-23 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 PANTHER PTHR11014:SF72 1 276 3.1E-225 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 PANTHER PTHR11014:SF72 294 467 3.1E-225 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 Gene3D G3DSA:3.40.630.10 377 463 1.5E-63 T 16-09-2016 Spa2297_RS21895 5384c36d7fb4dedf014eca66429e9201 470 Gene3D G3DSA:3.40.630.10 11 201 1.5E-63 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 SUPERFAMILY SSF55021 3 75 1.27E-22 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.2E-28 T 16-09-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 Pfam PF01842 ACT domain 4 69 1.4E-16 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 Gene3D G3DSA:3.30.70.1150 84 163 1.4E-30 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 PANTHER PTHR30239 3 173 6.3E-89 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 7.0E-34 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 SUPERFAMILY SSF55021 81 161 1.48E-25 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 Gene3D G3DSA:3.30.70.260 1 78 1.2E-33 T 16-09-2016 Spa2297_RS23335 2d92a3f5399b2f3ec9e0304495bb0e5d 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 4.2E-60 T 16-09-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 4.5E-24 T 16-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 Gene3D G3DSA:2.60.15.10 4 91 4.2E-25 T 16-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 108 1.4E-25 T 16-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 SUPERFAMILY SSF51344 5 85 2.35E-21 T 16-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 120 18.439 T 16-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 PANTHER PTHR13822 5 124 1.9E-31 T 16-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22705 c61d670368752e38c18cb368b3b87c3c 124 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 18 90 2.0E-33 T 16-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS21365 ffc9bfa7d4a53b355d6c5f254318cf77 92 PANTHER PTHR38839 1 83 2.7E-18 T 16-09-2016 Spa2297_RS21365 ffc9bfa7d4a53b355d6c5f254318cf77 92 Pfam PF02467 Transcription factor WhiB 2 64 1.4E-19 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS21365 ffc9bfa7d4a53b355d6c5f254318cf77 92 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 83 12.897 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS21365 ffc9bfa7d4a53b355d6c5f254318cf77 92 PANTHER PTHR38839:SF1 1 83 2.7E-18 T 16-09-2016 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 205 227 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 337 352 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 291 302 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 161 176 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 309 336 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 144 160 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 98 109 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 358 367 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PRINTS PR00359 B-class P450 signature 367 378 1.4E-50 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 SUPERFAMILY SSF48264 14 420 1.7E-101 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 PANTHER PTHR11712 8 420 8.4E-135 T 16-09-2016 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 Pfam PF00067 Cytochrome P450 192 387 1.2E-21 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS13460 54adebf0fa2548951ccacef660967be9 434 Gene3D G3DSA:1.10.630.10 12 421 5.0E-133 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01450 c642ea9f79d1b3c1ab105eebf640fc27 357 Gene3D G3DSA:3.40.190.10 140 245 9.7E-19 T 16-09-2016 Spa2297_RS01450 c642ea9f79d1b3c1ab105eebf640fc27 357 Pfam PF09084 NMT1/THI5 like 130 219 6.9E-12 T 16-09-2016 IPR015168 SsuA/THI5-like Spa2297_RS01450 c642ea9f79d1b3c1ab105eebf640fc27 357 PANTHER PTHR30024 70 314 1.2E-17 T 16-09-2016 Spa2297_RS01450 c642ea9f79d1b3c1ab105eebf640fc27 357 SUPERFAMILY SSF53850 54 278 2.79E-31 T 16-09-2016 Spa2297_RS22400 42952521f043d7719a184cb010d007fc 453 Pfam PF01098 Cell cycle protein 91 448 3.3E-73 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS22400 42952521f043d7719a184cb010d007fc 453 PANTHER PTHR30474 66 453 2.1E-204 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS22400 42952521f043d7719a184cb010d007fc 453 PANTHER PTHR30474:SF3 66 453 2.1E-204 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Gene3D G3DSA:3.40.1110.10 903 939 3.4E-7 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF56784 911 931 4.8E-43 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF56784 1030 1281 4.8E-43 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF81665 814 907 1.44E-49 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF81665 640 702 1.44E-49 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF81665 1227 1416 1.44E-49 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Gene3D G3DSA:1.20.1110.10 644 697 2.6E-56 T 16-09-2016 IPR023298 P-type ATPase, transmembrane domain Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Gene3D G3DSA:1.20.1110.10 1146 1414 2.6E-56 T 16-09-2016 IPR023298 P-type ATPase, transmembrane domain Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1033 1051 1.5E-14 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1209 1234 1.5E-14 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1177 1193 1.5E-14 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1149 1165 1.5E-14 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 677 958 7.8E-30 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1127 1259 2.6E-28 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PANTHER PTHR24093:SF268 578 1295 2.3E-230 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Gene3D G3DSA:3.40.1110.10 971 1080 3.2E-13 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PANTHER PTHR24093 578 1295 2.3E-230 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Pfam PF00122 E1-E2 ATPase 670 904 1.6E-49 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 SUPERFAMILY SSF81653 713 811 4.18E-21 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1076 1087 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1098 1108 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 753 767 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 913 927 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1177 1196 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1201 1213 1.1E-28 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Pfam PF00702 haloacid dehalogenase-like hydrolase 909 1191 5.0E-20 T 16-09-2016 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Gene3D G3DSA:2.70.150.10 698 812 1.3E-23 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 915 921 - T 16-09-2016 IPR018303 P-type ATPase, phosphorylation site Spa2297_RS10545 e1085e852a2a5f86cc08a9846d84653d 1444 Pfam PF00689 Cation transporting ATPase, C-terminus 1262 1413 6.4E-16 T 16-09-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal Spa2297_RS07260 798f9d5f5babd999b1c3d0ede83b4d73 544 PANTHER PTHR11819:SF13 21 538 4.6E-256 T 16-09-2016 Spa2297_RS07260 798f9d5f5babd999b1c3d0ede83b4d73 544 Pfam PF00474 Sodium:solute symporter family 52 467 3.7E-93 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS07260 798f9d5f5babd999b1c3d0ede83b4d73 544 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 52 466 8.9E-57 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS07260 798f9d5f5babd999b1c3d0ede83b4d73 544 PANTHER PTHR11819 21 538 4.6E-256 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Gene3D G3DSA:3.20.20.70 498 833 1.2E-76 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Gene3D G3DSA:3.20.20.70 35 367 1.8E-64 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Hamap MF_01611 FO synthase subunit 1 [cofG]. 75 406 50.736 T 16-09-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 SMART SM00729 79 316 1.6E-6 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 534 841 1.7E-108 T 16-09-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 499 844 6.2E-161 T 16-09-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 PANTHER PTHR22976 459 867 0.0 T 16-09-2016 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 SUPERFAMILY SSF102114 37 381 7.95E-36 T 16-09-2016 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 76 404 2.5E-143 T 16-09-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Pfam PF04055 Radical SAM superfamily 84 265 1.4E-13 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Pfam PF04055 Radical SAM superfamily 542 702 7.9E-16 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 Hamap MF_01612 FO synthase subunit 2 [cofH]. 485 845 48.585 T 16-09-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 PANTHER PTHR22976:SF22 459 867 0.0 T 16-09-2016 Spa2297_RS14305 48ad4f5ebc19dbf8faee89addc4d33e2 867 SUPERFAMILY SSF102114 497 808 1.2E-50 T 16-09-2016 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Pfam PF04545 Sigma-70, region 4 270 319 2.3E-16 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 SUPERFAMILY SSF88659 178 252 1.87E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PRINTS PR00046 Major sigma-70 factor signature 291 306 1.2E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PRINTS PR00046 Major sigma-70 factor signature 306 317 1.2E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PRINTS PR00046 Major sigma-70 factor signature 153 161 1.2E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PRINTS PR00046 Major sigma-70 factor signature 129 142 1.2E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PRINTS PR00046 Major sigma-70 factor signature 274 286 1.2E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Gene3D G3DSA:1.10.10.10 173 228 1.5E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Gene3D G3DSA:1.10.601.10 97 172 4.2E-27 T 16-09-2016 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Pfam PF04539 Sigma-70 region 3 186 244 4.9E-14 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 SUPERFAMILY SSF88946 75 174 6.28E-33 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PANTHER PTHR30385 29 325 8.7E-109 T 16-09-2016 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Gene3D G3DSA:1.10.10.10 262 321 4.7E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 101 321 4.9E-38 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 PANTHER PTHR30385:SF4 29 325 8.7E-109 T 16-09-2016 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 99 321 1.9E-95 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 SUPERFAMILY SSF88659 241 321 8.22E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22185 e85ad6ed4ec179f6918b0d801fac14c5 325 Pfam PF04542 Sigma-70 region 2 105 174 3.5E-21 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 Gene3D G3DSA:1.10.10.10 148 209 1.6E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 191 7.1E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 SMART SM00448 1 118 8.2E-8 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 SUPERFAMILY SSF52172 2 165 1.28E-18 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 PANTHER PTHR26402:SF582 1 205 3.4E-78 T 16-09-2016 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 SMART SM00421 144 206 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.1E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.1E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.1E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 Gene3D G3DSA:3.40.50.2300 2 147 4.5E-25 T 16-09-2016 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 PANTHER PTHR26402 1 205 3.4E-78 T 16-09-2016 Spa2297_RS19700 1de62d1b89943707e429b85204e29c73 210 Pfam PF00072 Response regulator receiver domain 2 105 1.3E-14 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS06460 668477fbfcaa29be4d60ef665d658b22 330 SUPERFAMILY SSF159659 3 260 1.07E-88 T 16-09-2016 Spa2297_RS06460 668477fbfcaa29be4d60ef665d658b22 330 PIRSF PIRSF028754 2 288 5.8E-128 T 16-09-2016 IPR008492 Protein of unknown function DUF774 Spa2297_RS06460 668477fbfcaa29be4d60ef665d658b22 330 Pfam PF09754 PAC2 family 19 236 3.4E-53 T 16-09-2016 IPR019151 Proteasome assembly chaperone 2 Spa2297_RS06460 668477fbfcaa29be4d60ef665d658b22 330 PANTHER PTHR42301:SF2 2 288 3.4E-206 T 16-09-2016 Spa2297_RS06460 668477fbfcaa29be4d60ef665d658b22 330 PANTHER PTHR42301 2 288 3.4E-206 T 16-09-2016 Spa2297_RS22150 e5d15bee9043f15ebdf0243a205b7278 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 263 3.2E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22150 e5d15bee9043f15ebdf0243a205b7278 276 SUPERFAMILY SSF161098 2 276 4.02E-71 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22150 e5d15bee9043f15ebdf0243a205b7278 276 PANTHER PTHR32243 1 276 2.6E-152 T 16-09-2016 Spa2297_RS22150 e5d15bee9043f15ebdf0243a205b7278 276 PANTHER PTHR32243:SF42 1 276 2.6E-152 T 16-09-2016 Spa2297_RS22150 e5d15bee9043f15ebdf0243a205b7278 276 Gene3D G3DSA:1.10.3720.10 4 263 2.3E-64 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 PANTHER PTHR11986:SF79 4 381 1.2E-154 T 16-09-2016 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 Pfam PF00202 Aminotransferase class-III 8 370 9.8E-104 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 373 8.0E-137 T 16-09-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 Gene3D G3DSA:3.90.1150.10 270 375 1.0E-34 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 200 238 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 PANTHER PTHR11986 4 381 1.2E-154 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 Gene3D G3DSA:3.40.640.10 43 269 2.8E-84 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 374 42.062 T 16-09-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Spa2297_RS06070 a6132713f518c31e0e0be0c931d3cc7a 388 SUPERFAMILY SSF53383 3 374 4.59E-120 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 Pfam PF03466 LysR substrate binding domain 95 302 4.0E-42 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 PANTHER PTHR30419 4 309 3.2E-112 T 16-09-2016 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 4.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 4.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 4.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 SUPERFAMILY SSF53850 97 307 1.9E-36 T 16-09-2016 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 Gene3D G3DSA:3.40.190.10 181 276 2.8E-25 T 16-09-2016 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 Gene3D G3DSA:1.10.10.10 9 92 9.4E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 4.0E-19 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 PANTHER PTHR30419:SF4 4 309 3.2E-112 T 16-09-2016 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 Gene3D G3DSA:3.40.190.10 97 180 4.7E-19 T 16-09-2016 Spa2297_RS21305 bf2aa3bc620fa10bc998471534967fe3 312 SUPERFAMILY SSF46785 6 117 6.36E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32165 f9cd47ebba5111af42affe3f07a99741 142 Gene3D G3DSA:3.30.530.20 3 137 1.1E-43 T 16-09-2016 IPR023393 START-like domain Spa2297_RS32165 f9cd47ebba5111af42affe3f07a99741 142 SUPERFAMILY SSF55961 3 135 1.63E-32 T 16-09-2016 Spa2297_RS32165 f9cd47ebba5111af42affe3f07a99741 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 135 1.3E-26 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS32165 f9cd47ebba5111af42affe3f07a99741 142 PANTHER PTHR31213:SF24 1 137 3.8E-20 T 16-09-2016 Spa2297_RS32165 f9cd47ebba5111af42affe3f07a99741 142 PANTHER PTHR31213 1 137 3.8E-20 T 16-09-2016 Spa2297_RS15775 703dd4d8ac39af9ba44523c0126de39f 265 Gene3D G3DSA:1.20.120.450 12 74 6.2E-8 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS15775 703dd4d8ac39af9ba44523c0126de39f 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 159 5.9E-14 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS15775 703dd4d8ac39af9ba44523c0126de39f 265 SUPERFAMILY SSF109854 10 163 3.62E-13 T 16-09-2016 Spa2297_RS15775 703dd4d8ac39af9ba44523c0126de39f 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 236 8.0E-19 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS25310 a467c2d6d9118c38fcda4bfa2898d6fe 541 Pfam PF11380 Stealth protein CR2, conserved region 2 270 375 1.7E-43 T 16-09-2016 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 KEGG: 00563+2.7.-.- Spa2297_RS25310 a467c2d6d9118c38fcda4bfa2898d6fe 541 PANTHER PTHR24045 56 541 1.1E-102 T 16-09-2016 Spa2297_RS25310 a467c2d6d9118c38fcda4bfa2898d6fe 541 Pfam PF17101 Stealth protein CR1, conserved region 1 235 258 3.2E-12 T 16-09-2016 IPR031358 Stealth protein CR1, conserved region 1 KEGG: 00563+2.7.-.- Spa2297_RS25310 a467c2d6d9118c38fcda4bfa2898d6fe 541 Pfam PF17103 Stealth protein CR4, conserved region 4 496 541 1.2E-13 T 16-09-2016 IPR031356 Stealth protein CR4, conserved region 4 Spa2297_RS25310 a467c2d6d9118c38fcda4bfa2898d6fe 541 Pfam PF17102 Stealth protein CR3, conserved region 3 421 468 9.7E-15 T 16-09-2016 IPR031357 Stealth protein CR3, conserved region 3 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PANTHER PTHR24078:SF255 1 119 2.7E-121 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 398 37.733 T 16-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Pfam PF00226 DnaJ domain 10 72 1.7E-26 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Pfam PF01556 DnaJ C terminal domain 151 364 2.2E-35 T 16-09-2016 IPR002939 Chaperone DnaJ, C-terminal Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Gene3D G3DSA:1.10.287.110 4 94 3.2E-30 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SMART SM00271 9 67 2.8E-28 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 16-09-2016 IPR018253 DnaJ domain, conserved site Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SUPERFAMILY SSF46565 9 112 9.29E-30 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PANTHER PTHR24078 1 119 2.7E-121 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Gene3D G3DSA:2.60.260.20 135 172 8.8E-23 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Gene3D G3DSA:2.60.260.20 241 285 8.8E-23 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PRINTS PR00625 DnaJ domain signature 67 86 3.2E-22 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PRINTS PR00625 DnaJ domain signature 30 45 3.2E-22 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PRINTS PR00625 DnaJ domain signature 12 30 3.2E-22 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PRINTS PR00625 DnaJ domain signature 47 67 3.2E-22 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 381 7.9E-122 T 16-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SUPERFAMILY SSF57938 165 240 1.7E-14 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PANTHER PTHR24078 139 390 2.7E-121 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Pfam PF00684 DnaJ central domain 178 238 2.2E-10 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 PANTHER PTHR24078:SF255 139 390 2.7E-121 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Gene3D G3DSA:2.10.230.10 173 240 2.0E-16 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 Gene3D G3DSA:2.60.260.20 287 365 3.9E-20 T 16-09-2016 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SUPERFAMILY SSF49493 145 199 7.19E-20 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SUPERFAMILY SSF49493 244 294 7.19E-20 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS17490 8d847581ef9610a471cb024a3f58b1a1 398 SUPERFAMILY SSF49493 290 375 7.33E-21 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PANTHER PTHR24421 66 406 3.1E-135 T 16-09-2016 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 3.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 3.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 3.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PIRSF PIRSF037434 1 401 1.2E-132 T 16-09-2016 IPR017205 Signal transduction histidine kinase, ChrS Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 SMART SM00387 298 396 2.0E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 SUPERFAMILY SSF55874 267 394 1.27E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 Gene3D G3DSA:3.30.565.10 275 400 2.8E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 395 2.4E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 Pfam PF07730 Histidine kinase 193 258 5.9E-17 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS04030 4a8e82cc41d0aae3983c670ae63d8e36 406 PANTHER PTHR24421:SF24 66 406 3.1E-135 T 16-09-2016 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 SUPERFAMILY SSF51556 24 359 1.13E-67 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 Gene3D G3DSA:3.20.20.140 26 364 4.7E-100 T 16-09-2016 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 30 362 2.9E-68 T 16-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 PANTHER PTHR11409:SF43 22 366 2.2E-97 T 16-09-2016 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 PANTHER PTHR11409 22 366 2.2E-97 T 16-09-2016 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 Pfam PF00962 Adenosine/AMP deaminase 29 362 6.0E-83 T 16-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Spa2297_RS20740 2fb63f69fe1ed43ec085be45311847bf 392 Hamap MF_00540 Adenosine deaminase [add]. 24 365 55.134 T 16-09-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 Pfam PF07690 Major Facilitator Superfamily 14 295 6.7E-24 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 SUPERFAMILY SSF103473 7 392 2.49E-45 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 PANTHER PTHR23526:SF1 1 407 9.6E-128 T 16-09-2016 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 Gene3D G3DSA:1.20.1250.20 10 189 1.8E-13 T 16-09-2016 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 PANTHER PTHR23526 1 407 9.6E-128 T 16-09-2016 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 PRINTS PR01035 Tetracycline resistance protein signature 134 156 6.5E-5 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 PRINTS PR01035 Tetracycline resistance protein signature 45 64 6.5E-5 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 PRINTS PR01035 Tetracycline resistance protein signature 241 261 6.5E-5 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS06710 d69c743fb1cf6bb9733684f08eb6900f 417 Gene3D G3DSA:1.20.1250.20 208 395 9.0E-23 T 16-09-2016 Spa2297_RS05970 c13adb1b5ab1fcc4dbd9e629e59095a0 244 PANTHER PTHR30450 3 224 6.9E-122 T 16-09-2016 Spa2297_RS05970 c13adb1b5ab1fcc4dbd9e629e59095a0 244 PANTHER PTHR30450:SF1 3 224 6.9E-122 T 16-09-2016 Spa2297_RS05970 c13adb1b5ab1fcc4dbd9e629e59095a0 244 SUPERFAMILY SSF161098 8 202 1.96E-42 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05970 c13adb1b5ab1fcc4dbd9e629e59095a0 244 Gene3D G3DSA:1.10.3720.10 8 215 1.3E-37 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05970 c13adb1b5ab1fcc4dbd9e629e59095a0 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 218 2.7E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05515 60c0737e5635b971baa56ecd54482564 117 SUPERFAMILY SSF52038 10 101 4.32E-22 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS05515 60c0737e5635b971baa56ecd54482564 117 Gene3D G3DSA:3.30.370.10 11 101 1.8E-21 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS05515 60c0737e5635b971baa56ecd54482564 117 Pfam PF01337 Barstar (barnase inhibitor) 12 96 5.8E-24 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 Gene3D G3DSA:1.10.10.60 13 64 1.9E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 SUPERFAMILY SSF46689 14 86 1.44E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 PANTHER PTHR30055 10 200 7.3E-28 T 16-09-2016 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.5E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.5E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 4.3E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 PANTHER PTHR30055:SF80 10 200 7.3E-28 T 16-09-2016 Spa2297_RS29250 fb44293a14f40920632abc1875545f0a 208 Gene3D G3DSA:1.10.357.10 65 207 6.8E-24 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS02350 fc6ee84fec324a036cb00a9f571c0ab2 130 SUPERFAMILY SSF54593 2 129 2.42E-29 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02350 fc6ee84fec324a036cb00a9f571c0ab2 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 1.4E-16 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS02350 fc6ee84fec324a036cb00a9f571c0ab2 130 Gene3D G3DSA:3.10.180.10 2 129 2.5E-26 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02350 fc6ee84fec324a036cb00a9f571c0ab2 130 PANTHER PTHR21366:SF8 1 128 1.2E-57 T 16-09-2016 Spa2297_RS02350 fc6ee84fec324a036cb00a9f571c0ab2 130 PANTHER PTHR21366 1 128 1.2E-57 T 16-09-2016 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 SUPERFAMILY SSF51735 338 522 1.34E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 PANTHER PTHR23309:SF2 53 695 0.0 T 16-09-2016 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 PANTHER PTHR23309 53 695 0.0 T 16-09-2016 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 62 237 1.2E-17 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Gene3D G3DSA:1.10.1040.10 526 611 2.7E-10 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Gene3D G3DSA:3.90.226.10 35 238 8.6E-33 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 606 3.3E-11 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 SUPERFAMILY SSF48179 522 615 1.62E-17 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Gene3D G3DSA:3.40.50.720 335 525 2.5E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 SUPERFAMILY SSF52096 253 327 1.54E-32 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 SUPERFAMILY SSF52096 34 220 1.54E-32 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 SUPERFAMILY SSF48179 634 700 2.3E-10 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS25335 8b94add564a8f4968c41d71fd49976ec 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 1.2E-57 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS15025 a12f8bd2729ca7d858618ed16b11c5b4 150 PANTHER PTHR35862:SF2 1 150 8.3E-72 T 16-09-2016 Spa2297_RS15025 a12f8bd2729ca7d858618ed16b11c5b4 150 Pfam PF04965 Gene 25-like lysozyme 26 115 9.8E-24 T 16-09-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD Spa2297_RS15025 a12f8bd2729ca7d858618ed16b11c5b4 150 SUPERFAMILY SSF160719 22 128 8.24E-32 T 16-09-2016 Spa2297_RS15025 a12f8bd2729ca7d858618ed16b11c5b4 150 Gene3D G3DSA:3.10.450.40 2 128 1.3E-45 T 16-09-2016 Spa2297_RS15025 a12f8bd2729ca7d858618ed16b11c5b4 150 PANTHER PTHR35862 1 150 8.3E-72 T 16-09-2016 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 Gene3D G3DSA:3.90.180.10 1 138 8.2E-37 T 16-09-2016 IPR011032 GroES-like Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 PANTHER PTHR11695 16 326 8.6E-120 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 PANTHER PTHR11695:SF31 16 326 8.6E-120 T 16-09-2016 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 133 154 - T 16-09-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 Gene3D G3DSA:3.40.50.720 139 254 3.4E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 SMART SM00829 13 315 1.7E-29 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 SUPERFAMILY SSF50129 1 133 6.29E-32 T 16-09-2016 IPR011032 GroES-like Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 Pfam PF00107 Zinc-binding dehydrogenase 144 261 1.1E-31 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS04325 3f15c3fde57a9af25e0847cb92ecc80c 326 SUPERFAMILY SSF51735 105 260 3.1E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08805 074ee2d57d9fced6d63eff9407290362 253 Gene3D G3DSA:1.20.1540.10 27 231 9.6E-37 T 16-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spa2297_RS08805 074ee2d57d9fced6d63eff9407290362 253 SUPERFAMILY SSF144091 25 233 1.96E-35 T 16-09-2016 Spa2297_RS08805 074ee2d57d9fced6d63eff9407290362 253 PANTHER PTHR22936 29 231 2.1E-27 T 16-09-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 Spa2297_RS08805 074ee2d57d9fced6d63eff9407290362 253 Pfam PF01694 Rhomboid family 87 235 1.2E-35 T 16-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 44 486 2.5E-149 T 16-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 626 674 5.1E-7 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 781 825 4.1E-10 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 570 605 1.1E-9 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 519 564 1.4E-14 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 678 726 3.2E-12 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 732 777 5.8E-13 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 PANTHER PTHR10169:SF48 8 801 0.0 T 16-09-2016 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 SMART SM00434 23 480 1.8E-281 T 16-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Gene3D G3DSA:3.30.1360.40 252 348 9.5E-34 T 16-09-2016 IPR024946 Arginine repressor C-terminal-like domain Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 PANTHER PTHR10169 8 801 0.0 T 16-09-2016 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 SUPERFAMILY SSF56719 42 502 3.92E-170 T 16-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 20 827 0.0 T 16-09-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 SUPERFAMILY SSF101904 514 834 1.7E-98 T 16-09-2016 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 15 829 27.312 T 16-09-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Gene3D G3DSA:3.90.199.10 42 251 7.0E-113 T 16-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Gene3D G3DSA:3.90.199.10 349 413 7.0E-113 T 16-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Spa2297_RS16600 5aa42e0683064e9bd49d43ec82d4c40b 864 Gene3D G3DSA:2.120.10.90 512 826 1.6E-117 T 16-09-2016 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 SUPERFAMILY SSF46689 9 82 3.69E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 PANTHER PTHR30055:SF80 5 204 6.8E-63 T 16-09-2016 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 Gene3D G3DSA:1.10.357.10 61 202 7.7E-19 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.8E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 5.8E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 PANTHER PTHR30055 5 204 6.8E-63 T 16-09-2016 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 63 1.6E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS15350 ff51b564b5678a8bbfa1270c3369f7ff 209 Gene3D G3DSA:1.10.10.60 8 60 1.2E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 SUPERFAMILY SSF46894 863 923 2.45E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 884 4.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 912 4.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 900 4.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 Pfam PF00196 Bacterial regulatory proteins, luxR family 869 922 6.9E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 Gene3D G3DSA:1.10.10.10 863 923 1.8E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 ProSitePatterns PS00622 LuxR-type HTH domain signature. 884 911 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 SUPERFAMILY SSF52540 28 196 1.23E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26805 c0fac72388e82d758527bd295c61005c 949 SMART SM00421 867 924 1.9E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 Gene3D G3DSA:3.40.190.120 158 258 3.5E-29 T 16-09-2016 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 PANTHER PTHR30177 53 320 9.8E-125 T 16-09-2016 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 PANTHER PTHR30177:SF12 53 320 9.8E-125 T 16-09-2016 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 53 315 7.1E-55 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 Gene3D G3DSA:3.40.190.10 49 157 1.5E-40 T 16-09-2016 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 Gene3D G3DSA:3.40.190.10 270 320 1.5E-40 T 16-09-2016 Spa2297_RS25570 4f8978136e491d0392877b22de663ab7 320 SUPERFAMILY SSF53850 52 319 1.52E-50 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SMART SM00471 145 255 9.6E-13 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SMART SM00954 337 447 2.2E-64 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Pfam PF04607 Region found in RelA / SpoT proteins 337 446 8.4E-37 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SUPERFAMILY SSF55021 761 842 1.62E-15 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Gene3D G3DSA:3.30.460.10 280 426 4.5E-49 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Pfam PF13291 ACT domain 762 838 4.0E-17 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 130 838 3.3E-257 T 16-09-2016 IPR004811 RelA/SpoT family GO:0015969 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Pfam PF13328 HD domain 130 277 2.4E-50 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Gene3D G3DSA:3.10.20.30 504 566 2.6E-22 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 PANTHER PTHR21262:SF0 78 841 0.0 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SUPERFAMILY SSF81271 492 564 2.4E-20 T 16-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SUPERFAMILY SSF109604 118 292 8.16E-71 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Pfam PF02824 TGS domain 505 564 1.4E-20 T 16-09-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 PANTHER PTHR21262 78 841 0.0 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 Gene3D G3DSA:3.30.70.260 764 836 5.7E-15 T 16-09-2016 Spa2297_RS05725 29473a976e390d6679a337bbdfd5cef1 846 SUPERFAMILY SSF81301 282 509 9.32E-64 T 16-09-2016 Spa2297_RS21880 5c0c0ec6c36af9655c940a2a0f3c0e24 128 Gene3D G3DSA:1.10.10.10 20 79 3.2E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21880 5c0c0ec6c36af9655c940a2a0f3c0e24 128 PANTHER PTHR10815:SF2 1 127 7.7E-44 T 16-09-2016 Spa2297_RS21880 5c0c0ec6c36af9655c940a2a0f3c0e24 128 PANTHER PTHR10815 1 127 7.7E-44 T 16-09-2016 Spa2297_RS21880 5c0c0ec6c36af9655c940a2a0f3c0e24 128 SUPERFAMILY SSF46767 19 80 6.8E-14 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS21880 5c0c0ec6c36af9655c940a2a0f3c0e24 128 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 21 106 2.4E-17 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 Gene3D G3DSA:3.40.80.10 269 418 2.8E-34 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 SMART SM00644 269 406 4.4E-41 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 Gene3D G3DSA:1.10.530.10 139 190 5.8E-4 T 16-09-2016 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 Gene3D G3DSA:1.10.530.10 33 94 5.8E-4 T 16-09-2016 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 278 407 2.6E-18 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 PANTHER PTHR30417:SF1 2 638 0.0 T 16-09-2016 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 SUPERFAMILY SSF55846 255 419 4.61E-36 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS02430 4980d5c43d441a488475cc804ecbc220 638 PANTHER PTHR30417 2 638 0.0 T 16-09-2016 Spa2297_RS04470 641b22f9e929dcb9a540c16695e547fc 224 Pfam PF01730 UreF 34 174 3.2E-18 T 16-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 Spa2297_RS04470 641b22f9e929dcb9a540c16695e547fc 224 PANTHER PTHR33620 5 224 3.8E-41 T 16-09-2016 Spa2297_RS04470 641b22f9e929dcb9a540c16695e547fc 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 2 224 18.184 T 16-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 Spa2297_RS04470 641b22f9e929dcb9a540c16695e547fc 224 PIRSF PIRSF009467 1 224 6.9E-45 T 16-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 Spa2297_RS01135 69bd64b4336c4fe358d6133cfe1dd001 172 SUPERFAMILY SSF55961 1 140 3.46E-21 T 16-09-2016 Spa2297_RS01135 69bd64b4336c4fe358d6133cfe1dd001 172 Gene3D G3DSA:3.30.530.20 4 137 3.6E-10 T 16-09-2016 IPR023393 START-like domain Spa2297_RS01135 69bd64b4336c4fe358d6133cfe1dd001 172 PANTHER PTHR33824:SF2 1 168 1.2E-32 T 16-09-2016 Spa2297_RS01135 69bd64b4336c4fe358d6133cfe1dd001 172 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 129 2.2E-12 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS01135 69bd64b4336c4fe358d6133cfe1dd001 172 PANTHER PTHR33824 1 168 1.2E-32 T 16-09-2016 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 271 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 SUPERFAMILY SSF53383 32 437 3.66E-110 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 Gene3D G3DSA:3.40.640.10 76 322 2.2E-71 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 PANTHER PTHR11986 1 444 1.2E-299 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 Gene3D G3DSA:3.90.1150.10 323 437 3.8E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 Gene3D G3DSA:3.90.1150.10 21 75 3.8E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 PANTHER PTHR11986:SF15 1 444 1.2E-299 T 16-09-2016 Spa2297_RS28200 7284d028125bdb69d20849c507b051ac 461 Pfam PF00202 Aminotransferase class-III 41 435 9.9E-91 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS23145 4a91004d3a85449cd52660a6f46e73a4 258 Pfam PF07179 SseB protein N-terminal domain 38 132 2.1E-12 T 16-09-2016 IPR009839 SseB protein N-terminal domain Spa2297_RS23145 4a91004d3a85449cd52660a6f46e73a4 258 Pfam PF14581 SseB protein C-terminal domain 146 256 9.9E-28 T 16-09-2016 IPR027945 SseB protein, C-terminal Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 16-09-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 PANTHER PTHR10772 10 101 8.5E-41 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.435 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 1.2E-32 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 PRINTS PR00297 10kDa chaperonin signature 10 25 2.3E-30 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 PRINTS PR00297 10kDa chaperonin signature 32 53 2.3E-30 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 PRINTS PR00297 10kDa chaperonin signature 66 78 2.3E-30 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 PRINTS PR00297 10kDa chaperonin signature 87 100 2.3E-30 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 SUPERFAMILY SSF50129 9 101 1.01E-32 T 16-09-2016 IPR011032 GroES-like Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 SMART SM00883 9 100 2.0E-51 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS20080 d843202662a2cc36d52669d9b58cb672 102 Gene3D G3DSA:2.30.33.40 10 101 2.3E-36 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS30405 8351a4c77431ecba7b7cc35f31bc7db3 302 PANTHER PTHR33824:SF2 1 248 2.4E-88 T 16-09-2016 Spa2297_RS30405 8351a4c77431ecba7b7cc35f31bc7db3 302 PANTHER PTHR33824 1 248 2.4E-88 T 16-09-2016 Spa2297_RS30405 8351a4c77431ecba7b7cc35f31bc7db3 302 Gene3D G3DSA:3.30.530.20 85 193 7.1E-7 T 16-09-2016 IPR023393 START-like domain Spa2297_RS30405 8351a4c77431ecba7b7cc35f31bc7db3 302 SUPERFAMILY SSF55961 82 212 6.16E-20 T 16-09-2016 Spa2297_RS30405 8351a4c77431ecba7b7cc35f31bc7db3 302 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 89 207 9.2E-15 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS22870 40362a4bd7a252a970efbd33df0e8f03 210 SUPERFAMILY SSF51219 7 207 3.66E-46 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS22870 40362a4bd7a252a970efbd33df0e8f03 210 Pfam PF01987 Mitochondrial biogenesis AIM24 3 200 9.8E-35 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS22870 40362a4bd7a252a970efbd33df0e8f03 210 PANTHER PTHR38074:SF1 1 202 1.5E-44 T 16-09-2016 Spa2297_RS22870 40362a4bd7a252a970efbd33df0e8f03 210 PANTHER PTHR38074 1 202 1.5E-44 T 16-09-2016 Spa2297_RS22870 40362a4bd7a252a970efbd33df0e8f03 210 Gene3D G3DSA:3.60.160.10 7 208 1.0E-43 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 PANTHER PTHR30173 8 388 1.8E-208 T 16-09-2016 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 Gene3D G3DSA:1.10.10.10 107 168 1.1E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 SUPERFAMILY SSF88946 5 94 1.65E-13 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 SUPERFAMILY SSF88659 105 168 2.83E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 Pfam PF08281 Sigma-70, region 4 117 166 2.4E-9 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 168 6.9E-13 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 Pfam PF04542 Sigma-70 region 2 17 78 7.7E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 Gene3D G3DSA:1.10.1740.10 5 101 7.0E-12 T 16-09-2016 Spa2297_RS20060 123fac79802788e91d07de6f64bed41a 417 PANTHER PTHR30173:SF15 8 388 1.8E-208 T 16-09-2016 Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 SMART SM01012 167 222 4.6E-7 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 Pfam PF13185 GAF domain 28 160 1.6E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 PIRSF PIRSF036625 6 234 1.0E-31 T 16-09-2016 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 Gene3D G3DSA:1.10.10.10 180 225 5.7E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 SUPERFAMILY SSF55781 27 160 1.32E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 Pfam PF03861 ANTAR domain 178 222 2.2E-7 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS17050 033b989da677dfb971dc1ba2c705d0fa 236 Gene3D G3DSA:3.30.450.40 27 160 5.4E-10 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 ProSitePatterns PS00211 ABC transporters family signature. 665 679 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 PANTHER PTHR32282:SF4 5 781 0.0 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 SUPERFAMILY SSF52540 477 748 1.12E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 ProSitePatterns PS00211 ABC transporters family signature. 347 361 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 SUPERFAMILY SSF52540 11 114 9.87E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:1.10.8.280 159 270 1.6E-24 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 SUPERFAMILY SSF52540 9 46 2.43E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 SUPERFAMILY SSF52540 278 442 2.43E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:1.20.1580.10 271 337 9.3E-29 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:1.20.1580.10 98 158 9.3E-29 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:1.20.1580.10 529 655 6.1E-46 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Pfam PF00005 ABC transporter 481 695 5.7E-10 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 PANTHER PTHR32282 5 781 0.0 T 16-09-2016 Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:3.40.50.300 338 455 1.5E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:3.40.50.300 4 56 1.5E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:3.40.50.300 470 527 1.6E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 Gene3D G3DSA:3.40.50.300 656 774 1.6E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29045 7df60b176915597b15690e885dd20488 781 SMART SM00382 489 743 1.4E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10005 a96581fa0764b973f35a11fc73894d96 338 SUPERFAMILY SSF51430 7 319 9.95E-90 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS10005 a96581fa0764b973f35a11fc73894d96 338 Pfam PF00248 Aldo/keto reductase family 22 318 4.5E-67 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS10005 a96581fa0764b973f35a11fc73894d96 338 Gene3D G3DSA:3.20.20.100 6 330 1.1E-100 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS10005 a96581fa0764b973f35a11fc73894d96 338 PANTHER PTHR11732:SF225 6 332 1.1E-176 T 16-09-2016 Spa2297_RS10005 a96581fa0764b973f35a11fc73894d96 338 PANTHER PTHR11732 6 332 1.1E-176 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 249 263 - T 16-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 Pfam PF05199 GMC oxidoreductase 363 502 6.4E-39 T 16-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 Pfam PF00732 GMC oxidoreductase 8 291 5.4E-55 T 16-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 SUPERFAMILY SSF51905 5 283 8.83E-73 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 SUPERFAMILY SSF51905 449 509 8.83E-73 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 Gene3D G3DSA:3.50.50.60 443 508 1.0E-103 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 Gene3D G3DSA:3.50.50.60 4 128 1.0E-103 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 Gene3D G3DSA:3.50.50.60 180 308 1.0E-103 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 SUPERFAMILY SSF54373 285 450 2.94E-37 T 16-09-2016 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 PANTHER PTHR11552:SF135 4 509 3.2E-189 T 16-09-2016 Spa2297_RS13290 bd4800612421a78eba3fe49710ec0cb6 522 PANTHER PTHR11552 4 509 3.2E-189 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 SMART SM00354 8 78 2.7E-24 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 PANTHER PTHR30146 8 340 4.3E-136 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 PANTHER PTHR30146:SF48 8 340 4.3E-136 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 Gene3D G3DSA:1.10.260.40 9 57 4.9E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.7E-16 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 SUPERFAMILY SSF53822 82 340 1.79E-68 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 Gene3D G3DSA:3.40.50.2300 185 318 6.1E-48 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 Pfam PF13377 Periplasmic binding protein-like domain 179 340 5.3E-33 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 Gene3D G3DSA:3.40.50.2300 58 184 9.4E-31 T 16-09-2016 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS04280 bebeb441c7c6a482c2003750b0e2c6c4 341 SUPERFAMILY SSF47413 8 65 1.36E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS10170 3a35343d0f9b51f0a769ab189b067135 426 PANTHER PTHR33371:SF2 1 411 1.7E-193 T 16-09-2016 Spa2297_RS10170 3a35343d0f9b51f0a769ab189b067135 426 Pfam PF02470 MlaD protein 39 115 9.2E-15 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS10170 3a35343d0f9b51f0a769ab189b067135 426 PANTHER PTHR33371 1 411 1.7E-193 T 16-09-2016 Spa2297_RS10170 3a35343d0f9b51f0a769ab189b067135 426 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 297 8.6E-52 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 15 127 1.3E-39 T 16-09-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 PANTHER PTHR12899 14 127 4.7E-40 T 16-09-2016 Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 Gene3D G3DSA:3.30.420.100 31 127 8.5E-39 T 16-09-2016 Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 1.0E-49 T 16-09-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 SUPERFAMILY SSF53137 14 125 3.05E-46 T 16-09-2016 Spa2297_RS19875 d43623b867b74ef5c2915e763c6bdf6f 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.673 T 16-09-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 Gene3D G3DSA:3.20.20.30 1 338 4.7E-79 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 PANTHER PTHR30137 1 342 1.2E-142 T 16-09-2016 Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 3.1E-218 T 16-09-2016 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 Pfam PF00296 Luciferase-like monooxygenase 1 294 2.2E-56 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 SUPERFAMILY SSF51679 1 333 9.55E-71 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS18680 96c305e1d6d70345d124a2d6e48bb54c 375 PANTHER PTHR30137:SF8 1 342 1.2E-142 T 16-09-2016 Spa2297_RS23070 a05b0bc0c3245370a078375d0268ce11 399 SUPERFAMILY SSF141523 247 373 1.96E-24 T 16-09-2016 Spa2297_RS23070 a05b0bc0c3245370a078375d0268ce11 399 PANTHER PTHR30582:SF2 4 399 5.2E-138 T 16-09-2016 Spa2297_RS23070 a05b0bc0c3245370a078375d0268ce11 399 Gene3D G3DSA:2.40.440.10 247 374 1.6E-19 T 16-09-2016 Spa2297_RS23070 a05b0bc0c3245370a078375d0268ce11 399 Pfam PF03734 L,D-transpeptidase catalytic domain 244 373 4.3E-14 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS23070 a05b0bc0c3245370a078375d0268ce11 399 PANTHER PTHR30582 4 399 5.2E-138 T 16-09-2016 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 TIGRFAM TIGR00896 CynX: cyanate transporter 28 394 6.6E-151 T 16-09-2016 IPR004747 Cyanate transport system protein GO:0016021 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 Pfam PF07690 Major Facilitator Superfamily 46 344 1.8E-19 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 PANTHER PTHR23523:SF2 9 424 6.5E-178 T 16-09-2016 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 SUPERFAMILY SSF103473 17 414 1.57E-44 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 Gene3D G3DSA:1.20.1250.20 235 415 7.4E-13 T 16-09-2016 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 Gene3D G3DSA:1.20.1250.20 30 216 1.1E-17 T 16-09-2016 Spa2297_RS07200 22cbd6b80d32f8d9617deac50ee06aed 424 PANTHER PTHR23523 9 424 6.5E-178 T 16-09-2016 Spa2297_RS19470 ff641208016de279ee7ebbd92bacfd65 242 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 45 187 2.1E-32 T 16-09-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Spa2297_RS19470 ff641208016de279ee7ebbd92bacfd65 242 PANTHER PTHR33269 25 219 2.4E-55 T 16-09-2016 Spa2297_RS19470 ff641208016de279ee7ebbd92bacfd65 242 PANTHER PTHR33269:SF4 25 219 2.4E-55 T 16-09-2016 Spa2297_RS14815 ff0c02980428c3c51f22a4f138a475ab 91 Gene3D G3DSA:3.10.20.30 3 89 1.5E-29 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS14815 ff0c02980428c3c51f22a4f138a475ab 91 Pfam PF02597 ThiS family 5 91 4.6E-17 T 16-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Spa2297_RS14815 ff0c02980428c3c51f22a4f138a475ab 91 SUPERFAMILY SSF54285 2 91 3.74E-23 T 16-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Spa2297_RS14815 ff0c02980428c3c51f22a4f138a475ab 91 PANTHER PTHR38031 1 91 8.1E-26 T 16-09-2016 Spa2297_RS14815 ff0c02980428c3c51f22a4f138a475ab 91 PANTHER PTHR38031:SF1 1 91 8.1E-26 T 16-09-2016 Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 PANTHER PTHR23029 1 214 2.5E-78 T 16-09-2016 Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 SUPERFAMILY SSF53254 4 199 9.56E-42 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 PANTHER PTHR23029:SF26 1 214 2.5E-78 T 16-09-2016 Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 198 2.9E-36 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 Gene3D G3DSA:3.40.50.1240 4 204 8.8E-45 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 SMART SM00855 6 166 5.9E-18 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS24595 80c441ae252c68912deb9ae18c8f1aaf 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 16-09-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 SMART SM00893 24 215 1.1E-59 T 16-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 SUPERFAMILY SSF52402 3 257 4.54E-70 T 16-09-2016 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 PANTHER PTHR21294 1 245 4.8E-97 T 16-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 Pfam PF01012 Electron transfer flavoprotein domain 25 210 9.8E-46 T 16-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 PANTHER PTHR21294:SF0 1 245 4.8E-97 T 16-09-2016 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 PIRSF PIRSF000090 3 262 3.5E-82 T 16-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Spa2297_RS03600 c6c952065bc946dcfcce5b8c51e50621 262 Gene3D G3DSA:3.40.50.620 3 261 4.9E-85 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423:SF468 456 474 8.4E-67 T 16-09-2016 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PRINTS PR00344 Bacterial sensor protein C-terminal signature 627 641 7.3E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 683 7.3E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 Pfam PF08376 Nitrate and nitrite sensing 96 345 7.5E-36 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423 504 702 8.4E-67 T 16-09-2016 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 592 702 4.9E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423:SF468 97 118 8.4E-67 T 16-09-2016 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423 97 118 8.4E-67 T 16-09-2016 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423:SF468 504 702 8.4E-67 T 16-09-2016 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 Gene3D G3DSA:3.30.565.10 551 707 5.0E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 SMART SM00387 589 705 1.2E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 Pfam PF00672 HAMP domain 367 436 5.2E-7 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 SUPERFAMILY SSF55874 546 703 4.06E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22350 cfa34d86855a7766fc8eca61aef63993 981 PANTHER PTHR24423 456 474 8.4E-67 T 16-09-2016 Spa2297_RS11645 7fb0b15c282f1c0eb5aaaea374a33547 266 SUPERFAMILY SSF51658 5 264 7.07E-46 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS11645 7fb0b15c282f1c0eb5aaaea374a33547 266 PANTHER PTHR12110:SF3 1 265 5.6E-79 T 16-09-2016 Spa2297_RS11645 7fb0b15c282f1c0eb5aaaea374a33547 266 PANTHER PTHR12110 1 265 5.6E-79 T 16-09-2016 Spa2297_RS11645 7fb0b15c282f1c0eb5aaaea374a33547 266 Pfam PF01261 Xylose isomerase-like TIM barrel 21 204 5.2E-32 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS11645 7fb0b15c282f1c0eb5aaaea374a33547 266 Gene3D G3DSA:3.20.20.150 1 263 8.5E-64 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 PANTHER PTHR18901 1 207 1.0E-30 T 16-09-2016 Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 SUPERFAMILY SSF56784 10 204 5.61E-35 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 Gene3D G3DSA:3.40.50.1000 74 203 6.3E-20 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 PANTHER PTHR18901:SF14 1 207 1.0E-30 T 16-09-2016 Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 Gene3D G3DSA:1.10.150.240 22 73 1.3E-9 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS14675 56c7d6c372b34ad90a398a7cb1f89f78 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 12 164 3.8E-14 T 16-09-2016 Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 Pfam PF13439 Glycosyltransferase Family 4 14 172 5.4E-33 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 Pfam PF13692 Glycosyl transferases group 1 188 328 7.6E-32 T 16-09-2016 Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 Gene3D G3DSA:3.40.50.2000 187 339 1.5E-27 T 16-09-2016 Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 SUPERFAMILY SSF53756 2 363 3.14E-86 T 16-09-2016 Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 PANTHER PTHR12526:SF368 1 363 2.9E-231 T 16-09-2016 Spa2297_RS05785 feaf4b8923064613ac86ea35b0116e6e 387 PANTHER PTHR12526 1 363 2.9E-231 T 16-09-2016 Spa2297_RS21440 95d3c577243aedbb4346aa0b9d3b09af 245 Pfam PF12833 Helix-turn-helix domain 148 220 1.5E-10 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS21440 95d3c577243aedbb4346aa0b9d3b09af 245 SMART SM00342 146 219 5.7E-4 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 Gene3D G3DSA:3.90.1310.10 73 142 1.9E-6 T 16-09-2016 Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 PANTHER PTHR30627:SF3 1 487 5.6E-211 T 16-09-2016 Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 PANTHER PTHR30627 1 487 5.6E-211 T 16-09-2016 Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 483 5.9E-69 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 Gene3D G3DSA:3.40.710.10 143 489 2.9E-92 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16725 56ffbaf26e3ea677fac6b009993c0fe5 490 SUPERFAMILY SSF56601 96 487 3.42E-87 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS32110 77205a5b795e8b655253abb8ab842708 294 Pfam PF04909 Amidohydrolase 4 281 1.0E-42 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS32110 77205a5b795e8b655253abb8ab842708 294 SUPERFAMILY SSF51556 3 282 1.43E-57 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS32110 77205a5b795e8b655253abb8ab842708 294 Gene3D G3DSA:3.20.20.140 1 283 1.0E-66 T 16-09-2016 Spa2297_RS32110 77205a5b795e8b655253abb8ab842708 294 PANTHER PTHR21240:SF1 1 291 4.1E-70 T 16-09-2016 Spa2297_RS32110 77205a5b795e8b655253abb8ab842708 294 PANTHER PTHR21240 1 291 4.1E-70 T 16-09-2016 Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 34 211 5.6E-41 T 16-09-2016 IPR004302 Chitin-binding protein, N-terminal Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 Gene3D G3DSA:2.70.50.50 34 214 3.1E-51 T 16-09-2016 Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 PANTHER PTHR34823:SF2 2 357 1.4E-109 T 16-09-2016 Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 PANTHER PTHR34823 2 357 1.4E-109 T 16-09-2016 Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 SUPERFAMILY SSF81296 34 215 2.38E-48 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS06825 3c9d511d44e26b18e27f3bed8b0708bb 362 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 318 352 8.3E-4 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 PANTHER PTHR15892:SF2 1 60 7.6E-24 T 16-09-2016 Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.341 T 16-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 PANTHER PTHR15892 1 60 7.6E-24 T 16-09-2016 Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 16-09-2016 IPR018038 Ribosomal protein L30, conserved site Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 7.0E-28 T 16-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.1E-16 T 16-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 PIRSF PIRSF002211 1 60 9.5E-29 T 16-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 SUPERFAMILY SSF55129 1 60 7.59E-21 T 16-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Spa2297_RS19885 941ff4dfd1b909203b7703099e8bbe3c 60 Gene3D G3DSA:3.30.1390.20 1 59 2.3E-27 T 16-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 PANTHER PTHR30204 1 245 1.4E-98 T 16-09-2016 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 Gene3D G3DSA:1.10.490.50 160 251 4.4E-34 T 16-09-2016 IPR012925 TipAS antibiotic-recognition domain Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 SUPERFAMILY SSF89082 160 251 3.79E-29 T 16-09-2016 IPR012925 TipAS antibiotic-recognition domain Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 Gene3D G3DSA:1.10.1660.10 58 107 5.1E-11 T 16-09-2016 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 PANTHER PTHR30204:SF5 1 245 1.4E-98 T 16-09-2016 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 Pfam PF13411 MerR HTH family regulatory protein 3 70 6.2E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 Pfam PF07739 TipAS antibiotic-recognition domain 131 246 5.5E-39 T 16-09-2016 IPR012925 TipAS antibiotic-recognition domain Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 SMART SM00422 3 72 5.7E-29 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 Gene3D G3DSA:1.10.1660.10 3 57 3.2E-24 T 16-09-2016 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 SUPERFAMILY SSF46955 3 106 8.06E-29 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.4E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 8.4E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18135 d00e56d872142044dec60fbd9133a09a 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.4E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS14320 d5325804dc6d984de8852d8406d94aa3 139 Pfam PF04075 Domain of unknown function (DUF385) 12 132 3.1E-36 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS14320 d5325804dc6d984de8852d8406d94aa3 139 SUPERFAMILY SSF50475 38 109 3.74E-8 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14320 d5325804dc6d984de8852d8406d94aa3 139 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 26 126 1.5E-23 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS14320 d5325804dc6d984de8852d8406d94aa3 139 Gene3D G3DSA:2.30.110.10 37 129 5.3E-8 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 Pfam PF13671 AAA domain 3 130 3.0E-8 T 16-09-2016 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 PANTHER PTHR22769 203 347 3.5E-55 T 16-09-2016 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 SUPERFAMILY SSF52540 3 183 2.43E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 SUPERFAMILY SSF55811 189 331 8.67E-24 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 PANTHER PTHR22769:SF24 203 347 3.5E-55 T 16-09-2016 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 Gene3D G3DSA:3.40.50.300 3 183 7.4E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 PRINTS PR00502 NUDIX hydrolase family signature 227 241 1.2E-6 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 PRINTS PR00502 NUDIX hydrolase family signature 241 256 1.2E-6 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 Pfam PF00293 NUDIX domain 202 327 6.0E-18 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS03565 3a04889a5894a53b18124824d632293e 347 Gene3D G3DSA:3.90.79.10 202 331 4.0E-24 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 SUPERFAMILY SSF52402 154 296 7.12E-19 T 16-09-2016 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 PRINTS PR01438 Universal stress protein signature 97 109 3.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 PRINTS PR01438 Universal stress protein signature 115 137 3.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 PRINTS PR01438 Universal stress protein signature 3 21 3.0E-11 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 SUPERFAMILY SSF52402 6 141 2.6E-26 T 16-09-2016 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 Pfam PF00582 Universal stress protein family 6 137 1.0E-22 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 Pfam PF00582 Universal stress protein family 154 294 2.2E-14 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 Gene3D G3DSA:3.40.50.620 148 296 2.4E-19 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 Gene3D G3DSA:3.40.50.620 4 140 1.4E-25 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 PANTHER PTHR31964:SF26 6 156 2.0E-35 T 16-09-2016 Spa2297_RS02445 cf61d0962a80d8e379224b99e6c60791 300 PANTHER PTHR31964 6 156 2.0E-35 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PANTHER PTHR30222:SF5 44 378 3.1E-88 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 289 308 8.0E-13 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 163 179 8.0E-13 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 131 144 8.0E-13 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 245 264 8.0E-13 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 Pfam PF13416 Bacterial extracellular solute-binding protein 78 352 2.8E-28 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 SUPERFAMILY SSF53850 52 394 1.45E-60 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 PANTHER PTHR30222 44 378 3.1E-88 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 Gene3D G3DSA:3.40.190.10 184 338 3.5E-42 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 Gene3D G3DSA:3.40.190.10 57 183 3.9E-11 T 16-09-2016 Spa2297_RS23900 37fa7de9cee0c29d678471672adf9cd7 396 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 9 32 8.2E-6 T 16-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 Pfam PF00753 Metallo-beta-lactamase superfamily 610 792 1.6E-13 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 PANTHER PTHR30619:SF2 236 860 1.0E-144 T 16-09-2016 Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 SMART SM00849 612 790 2.8E-8 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 Gene3D G3DSA:3.60.15.10 603 855 8.8E-22 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 PANTHER PTHR30619 236 860 1.0E-144 T 16-09-2016 Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 SUPERFAMILY SSF56281 598 856 2.49E-36 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 Pfam PF03772 Competence protein 289 563 4.3E-40 T 16-09-2016 IPR004477 ComEC/Rec2-related protein Spa2297_RS10825 249fb753c1055594a22c195d1cf9dc8c 860 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 310 487 3.2E-12 T 16-09-2016 IPR004477 ComEC/Rec2-related protein Spa2297_RS08785 cca965a6466108d3e1a58aa41b5451c5 341 Pfam PF00877 NlpC/P60 family 242 328 6.4E-25 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS08785 cca965a6466108d3e1a58aa41b5451c5 341 PANTHER PTHR21666 225 332 1.0E-35 T 16-09-2016 Spa2297_RS08785 cca965a6466108d3e1a58aa41b5451c5 341 SUPERFAMILY SSF54001 226 331 1.81E-38 T 16-09-2016 Spa2297_RS08785 cca965a6466108d3e1a58aa41b5451c5 341 Gene3D G3DSA:3.90.1720.10 226 331 3.5E-41 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 PANTHER PTHR11986:SF17 13 420 5.3E-186 T 16-09-2016 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 Pfam PF00202 Aminotransferase class-III 12 411 5.8E-116 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 Gene3D G3DSA:3.90.1150.10 299 413 8.8E-42 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 PANTHER PTHR11986 13 420 5.3E-186 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 Gene3D G3DSA:3.40.640.10 48 298 2.2E-86 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS03190 6a93b28f366940d6a64735ecf74f46b8 421 SUPERFAMILY SSF53383 9 412 2.61E-130 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SUPERFAMILY SSF49785 760 905 1.46E-26 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:2.102.20.10 340 491 2.2E-8 T 16-09-2016 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:2.60.120.260 766 913 1.0E-33 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PANTHER PTHR23421 54 366 9.2E-53 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:2.60.390.10 492 560 2.2E-15 T 16-09-2016 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Pfam PF13363 Beta-galactosidase, domain 3 503 558 2.4E-13 T 16-09-2016 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PRINTS PR00742 Glycosyl hydrolase family 35 signature 70 87 4.1E-10 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PRINTS PR00742 Glycosyl hydrolase family 35 signature 92 110 4.1E-10 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PRINTS PR00742 Glycosyl hydrolase family 35 signature 147 166 4.1E-10 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PRINTS PR00742 Glycosyl hydrolase family 35 signature 837 853 4.1E-10 T 16-09-2016 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 PANTHER PTHR23421:SF64 54 366 9.2E-53 T 16-09-2016 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SUPERFAMILY SSF51011 341 459 8.63E-9 T 16-09-2016 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Pfam PF13364 Beta-galactosidase jelly roll domain 600 726 3.5E-15 T 16-09-2016 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Pfam PF13364 Beta-galactosidase jelly roll domain 772 886 5.3E-27 T 16-09-2016 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Pfam PF01301 Glycosyl hydrolases family 35 240 320 1.1E-9 T 16-09-2016 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Pfam PF01301 Glycosyl hydrolases family 35 66 211 6.0E-45 T 16-09-2016 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SUPERFAMILY SSF117100 490 573 1.96E-18 T 16-09-2016 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:2.60.120.260 594 765 1.6E-38 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SMART SM01029 325 499 1.2E-47 T 16-09-2016 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SUPERFAMILY SSF49785 577 729 1.12E-21 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:3.20.20.80 54 239 4.3E-46 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 Gene3D G3DSA:3.20.20.80 244 324 1.3E-7 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS10255 4a27fc4159343a469a404a509dfce342 919 SUPERFAMILY SSF51445 57 320 7.83E-53 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 226 2.0E-64 T 16-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 300 16.834 T 16-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 PANTHER PTHR13767 9 300 6.9E-107 T 16-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 187 2.1E-47 T 16-09-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 PANTHER PTHR13767:SF2 9 300 6.9E-107 T 16-09-2016 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 243 301 2.7E-16 T 16-09-2016 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 SUPERFAMILY SSF88697 243 300 1.19E-9 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 188 230 1.0E-12 T 16-09-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal Spa2297_RS24175 8396b007de007b6ec3a5c24e3541f5b9 301 SUPERFAMILY SSF55120 8 229 7.84E-69 T 16-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 Gene3D G3DSA:3.40.50.2020 167 294 1.2E-46 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 4.2E-43 T 16-09-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 16-09-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 12 322 7.0E-113 T 16-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 PANTHER PTHR10210 1 323 3.1E-174 T 16-09-2016 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 Gene3D G3DSA:3.40.50.2020 9 166 4.7E-67 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 SUPERFAMILY SSF53271 77 313 8.21E-62 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.483 T 16-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 9.4E-24 T 16-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 SMART SM01400 12 128 3.2E-68 T 16-09-2016 Spa2297_RS13555 ce06c7c6dc95fe092a17528cb22cd06f 324 PANTHER PTHR10210:SF41 1 323 3.1E-174 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Gene3D G3DSA:1.10.1060.10 2 146 4.2E-38 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PANTHER PTHR11938:SF75 22 318 7.6E-130 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Gene3D G3DSA:3.50.50.60 243 396 3.8E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 465 7.1E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 SUPERFAMILY SSF51971 144 409 2.35E-58 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 SUPERFAMILY SSF51971 393 477 4.36E-10 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 SUPERFAMILY SSF46548 5 155 2.09E-37 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Gene3D G3DSA:3.50.50.60 397 477 1.4E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PANTHER PTHR11938 22 318 7.6E-130 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 484 2.1E-185 T 16-09-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Gene3D G3DSA:3.50.50.60 147 242 4.0E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 42 132 2.8E-20 T 16-09-2016 IPR028261 Dihydroprymidine dehydrogenase domain II Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PANTHER PTHR11938:SF75 335 476 7.6E-130 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PANTHER PTHR11938 335 476 7.6E-130 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.4E-22 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.4E-22 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.4E-22 T 16-09-2016 Spa2297_RS07995 7f95c9ec66ca7523a10caeaf3085d2ca 496 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.4E-22 T 16-09-2016 Spa2297_RS30415 2608f236571bf5923e49f7780c3110dd 92 Pfam PF05120 Gas vesicle protein G 7 76 1.5E-26 T 16-09-2016 IPR007804 Gas vesicle protein GvpG Spa2297_RS12385 a877f3f97b30a3a84c4cfeb61b925f7b 106 SUPERFAMILY SSF103481 6 104 1.83E-17 T 16-09-2016 Spa2297_RS12385 a877f3f97b30a3a84c4cfeb61b925f7b 106 PANTHER PTHR30561 1 106 5.6E-48 T 16-09-2016 Spa2297_RS12385 a877f3f97b30a3a84c4cfeb61b925f7b 106 PANTHER PTHR30561:SF0 1 106 5.6E-48 T 16-09-2016 Spa2297_RS12385 a877f3f97b30a3a84c4cfeb61b925f7b 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.5E-25 T 16-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 SUPERFAMILY SSF46689 6 72 3.09E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 SUPERFAMILY SSF48498 78 181 7.41E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 PANTHER PTHR30055:SF87 3 187 8.9E-47 T 16-09-2016 Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 Gene3D G3DSA:1.10.357.10 51 184 1.2E-35 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 PANTHER PTHR30055 3 187 8.9E-47 T 16-09-2016 Spa2297_RS00920 ebde97ce572acc5b84ea5d812f713773 190 Gene3D G3DSA:1.10.10.60 3 49 1.5E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 Hamap MF_00163 Peptide deformylase [def]. 12 175 26.758 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 20 168 6.7E-36 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 Gene3D G3DSA:3.90.45.10 16 177 4.1E-56 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PIRSF PIRSF004749 7 177 3.8E-40 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PANTHER PTHR10458 13 178 8.9E-59 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 SUPERFAMILY SSF56420 13 171 2.36E-52 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 Pfam PF01327 Polypeptide deformylase 18 161 2.1E-41 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PRINTS PR01576 Peptide deformylase signature 102 113 5.2E-30 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PRINTS PR01576 Peptide deformylase signature 133 162 5.2E-30 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PRINTS PR01576 Peptide deformylase signature 43 72 5.2E-30 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS04375 85f9730829446785f3bd17da31adc41d 179 PRINTS PR01576 Peptide deformylase signature 114 132 5.2E-30 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 8.5E-9 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 8.5E-9 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 8.5E-9 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 PIRSF PIRSF000728 13 293 5.3E-100 T 16-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 PANTHER PTHR23342 8 295 2.3E-111 T 16-09-2016 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 SUPERFAMILY SSF53633 7 295 4.84E-86 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 267 2.7E-74 T 16-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 Pfam PF00696 Amino acid kinase family 28 270 1.8E-49 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 Gene3D G3DSA:3.40.1160.10 26 292 2.3E-98 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS06075 7fc94bf37b0c557e491745ef86d7263f 299 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 293 34.462 T 16-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 PANTHER PTHR33164 17 161 8.7E-50 T 16-09-2016 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 SUPERFAMILY SSF46785 15 155 1.86E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 PANTHER PTHR33164:SF11 17 161 8.7E-50 T 16-09-2016 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 SMART SM00347 43 143 1.9E-14 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 Gene3D G3DSA:1.10.10.10 20 154 3.3E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 8.4E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 8.4E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 8.4E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00165 8d7444bd0331c273451fe7d502ba1fce 168 Pfam PF12802 MarR family 48 107 2.8E-10 T 16-09-2016 Spa2297_RS14880 cb6a95f84a08213a346e9542f4aac888 156 Pfam PF00583 Acetyltransferase (GNAT) family 57 139 7.3E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14880 cb6a95f84a08213a346e9542f4aac888 156 SUPERFAMILY SSF55729 7 143 2.24E-14 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14880 cb6a95f84a08213a346e9542f4aac888 156 Gene3D G3DSA:3.40.630.30 7 145 1.1E-16 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 Gene3D G3DSA:3.40.50.10490 9 246 7.4E-69 T 16-09-2016 Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 SUPERFAMILY SSF53697 9 210 4.67E-22 T 16-09-2016 Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 Pfam PF13580 SIS domain 9 146 5.7E-40 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 PANTHER PTHR30390 3 251 2.6E-72 T 16-09-2016 Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 PANTHER PTHR30390:SF6 3 251 2.6E-72 T 16-09-2016 Spa2297_RS14460 9b945c242edbe89a08573dfb98db7969 251 Hamap MF_01240 UPF0309 protein . 6 250 38.856 T 16-09-2016 IPR022951 Uncharacterised protein family UPF0309 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Gene3D G3DSA:1.10.10.10 7 52 2.1E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Pfam PF13412 Winged helix-turn-helix DNA-binding 188 224 3.7E-5 T 16-09-2016 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Gene3D G3DSA:1.10.10.10 184 225 1.8E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 PANTHER PTHR30154:SF12 173 321 3.7E-38 T 16-09-2016 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 SMART SM00344 8 112 6.0E-4 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 SMART SM00344 184 285 3.2E-5 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Pfam PF01037 Lrp/AsnC ligand binding domain 246 315 9.6E-10 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 SUPERFAMILY SSF46785 8 55 1.61E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 PANTHER PTHR30154 173 321 3.7E-38 T 16-09-2016 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 1.4E-6 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 1.4E-6 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 1.4E-6 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 SUPERFAMILY SSF54909 239 318 2.15E-11 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 SUPERFAMILY SSF46785 184 230 9.62E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Pfam PF13404 AsnC-type helix-turn-helix domain 9 48 3.0E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Gene3D G3DSA:3.30.70.920 73 144 8.5E-5 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS27280 b04885512c5385dff730ebc6da28ca69 327 Gene3D G3DSA:3.30.70.920 243 318 2.7E-13 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS10300 f794e26b62d19e58712b89d274fef01e 106 Gene3D G3DSA:3.30.750.24 1 89 2.6E-13 T 16-09-2016 IPR002645 STAS domain Spa2297_RS10300 f794e26b62d19e58712b89d274fef01e 106 SUPERFAMILY SSF52091 1 90 8.24E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS10300 f794e26b62d19e58712b89d274fef01e 106 Pfam PF13466 STAS domain 18 89 4.1E-12 T 16-09-2016 IPR002645 STAS domain Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 4 280 3.3E-67 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 Gene3D G3DSA:3.20.20.70 3 281 3.6E-82 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 PANTHER PTHR30304 2 275 7.8E-66 T 16-09-2016 Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 281 1.1E-75 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 PIRSF PIRSF001359 1 285 3.1E-69 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS03485 554556fc86e36a88520f140bc855ae48 286 SUPERFAMILY SSF51569 2 281 2.93E-78 T 16-09-2016 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Gene3D G3DSA:3.90.182.10 36 217 1.3E-43 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Gene3D G3DSA:3.90.182.10 251 293 1.3E-43 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Pfam PF07691 PA14 domain 40 178 1.8E-25 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Gene3D G3DSA:2.60.120.260 314 477 1.3E-54 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 619 731 1.1E-13 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Pfam PF00703 Glycosyl hydrolases family 2 528 577 4.5E-8 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 SUPERFAMILY SSF51445 574 852 2.64E-61 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Gene3D G3DSA:2.60.40.320 478 578 1.9E-17 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 SUPERFAMILY SSF49785 314 487 1.7E-47 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Gene3D G3DSA:3.20.20.80 589 851 5.8E-51 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 PANTHER PTHR10066:SF44 295 856 1.6E-274 T 16-09-2016 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 SUPERFAMILY SSF56988 39 262 1.7E-55 T 16-09-2016 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 358 453 5.5E-13 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 PANTHER PTHR10066 295 856 1.6E-274 T 16-09-2016 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 SUPERFAMILY SSF49303 494 577 1.21E-12 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS28855 b6c963ca5188b00f2a4c77b82b3196f4 869 SMART SM00758 38 180 1.7E-42 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 SUPERFAMILY SSF52096 7 190 1.52E-65 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 SUPERFAMILY SSF52096 246 334 1.52E-65 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 Gene3D G3DSA:3.90.226.10 7 200 8.0E-58 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 PANTHER PTHR11941 246 320 3.3E-114 T 16-09-2016 Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 PANTHER PTHR11941 1 190 3.3E-114 T 16-09-2016 Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 Pfam PF16113 Enoyl-CoA hydratase/isomerase 17 337 6.9E-126 T 16-09-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 Gene3D G3DSA:1.10.12.10 263 320 5.7E-4 T 16-09-2016 IPR014748 Crontonase, C-terminal Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 PANTHER PTHR11941:SF53 246 320 3.3E-114 T 16-09-2016 Spa2297_RS31510 08c3bdcf2b5eeb6dbf7efd80eb9b19ae 349 PANTHER PTHR11941:SF53 1 190 3.3E-114 T 16-09-2016 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 SUPERFAMILY SSF52172 1 127 4.55E-32 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 Gene3D G3DSA:1.10.10.10 167 202 2.5E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 PANTHER PTHR26402:SF434 2 200 1.1E-105 T 16-09-2016 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 PANTHER PTHR26402 2 200 1.1E-105 T 16-09-2016 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 SUPERFAMILY SSF46785 167 221 9.4E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 Pfam PF00072 Response regulator receiver domain 4 116 4.1E-23 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 SMART SM00448 2 116 6.5E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 Pfam PF08279 HTH domain 165 204 4.2E-11 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 Gene3D G3DSA:3.40.50.2300 1 126 2.2E-29 T 16-09-2016 Spa2297_RS24700 c5ad1ff2b8e9a7a7b30b4176d00f562e 226 PIRSF PIRSF006171 1 226 1.1E-79 T 16-09-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 SUPERFAMILY SSF52343 331 463 4.06E-33 T 16-09-2016 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PRINTS PR00410 Phenol hydroxylase reductase family signature 259 271 4.6E-12 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PRINTS PR00410 Phenol hydroxylase reductase family signature 362 371 4.6E-12 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PRINTS PR00410 Phenol hydroxylase reductase family signature 337 356 4.6E-12 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PRINTS PR00410 Phenol hydroxylase reductase family signature 322 331 4.6E-12 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PRINTS PR00410 Phenol hydroxylase reductase family signature 430 438 4.6E-12 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Pfam PF03473 MOSC domain 50 161 2.4E-18 T 16-09-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Pfam PF00175 Oxidoreductase NAD-binding domain 338 444 2.6E-12 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 SUPERFAMILY SSF63380 225 327 9.36E-23 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Gene3D G3DSA:2.40.33.20 3 215 3.4E-61 T 16-09-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Gene3D G3DSA:2.40.30.10 225 328 5.0E-25 T 16-09-2016 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Gene3D G3DSA:3.10.20.30 459 572 4.1E-21 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 PANTHER PTHR22924 225 465 1.4E-55 T 16-09-2016 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 SUPERFAMILY SSF54292 453 573 1.27E-19 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 506 565 1.1E-8 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Pfam PF03475 3-alpha domain 172 212 1.0E-12 T 16-09-2016 IPR005163 3-alpha domain Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 SUPERFAMILY SSF50800 3 215 5.75E-57 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Gene3D G3DSA:3.40.50.80 329 458 1.7E-31 T 16-09-2016 Spa2297_RS25550 5f28c80126d73b3150cb0dc3be76dd07 573 Pfam PF00970 Oxidoreductase FAD-binding domain 260 327 1.3E-8 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Gene3D G3DSA:3.30.300.30 520 640 8.0E-29 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Gene3D G3DSA:2.30.38.10 440 516 5.4E-7 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Pfam PF00501 AMP-binding enzyme 89 523 1.8E-91 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 532 610 6.8E-27 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 2.4E-20 T 16-09-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 644 50.804 T 16-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 PANTHER PTHR24095 31 644 3.8E-274 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Gene3D G3DSA:3.40.50.980 267 425 1.6E-27 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 SUPERFAMILY SSF56801 31 640 9.55E-176 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 Gene3D G3DSA:3.40.50.980 81 266 3.0E-43 T 16-09-2016 Spa2297_RS17900 9b601609bb61fbe195165504a8fba1a5 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 25 642 2.0E-297 T 16-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 SUPERFAMILY SSF55729 144 195 7.95E-35 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 SUPERFAMILY SSF55729 5 115 7.95E-35 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 PANTHER PTHR36174:SF1 140 373 8.3E-153 T 16-09-2016 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 Gene3D G3DSA:3.40.630.30 186 346 5.0E-53 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 PANTHER PTHR36174 1 123 8.3E-153 T 16-09-2016 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 SUPERFAMILY SSF55729 184 366 7.42E-36 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 PANTHER PTHR36174 140 373 8.3E-153 T 16-09-2016 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 PANTHER PTHR36174:SF1 1 123 8.3E-153 T 16-09-2016 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 Pfam PF02388 FemAB family 8 249 8.3E-28 T 16-09-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 Pfam PF02388 FemAB family 265 366 3.6E-17 T 16-09-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 Gene3D G3DSA:3.40.630.30 149 185 1.2E-53 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16450 781564c809e97077e3bf1abfb6533418 373 Gene3D G3DSA:3.40.630.30 1 117 1.2E-53 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 1.3E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 1.3E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 349 1.3E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SMART SM00387 254 370 3.7E-32 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Gene3D G3DSA:3.30.565.10 247 369 6.0E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Gene3D G3DSA:3.30.565.10 182 214 6.0E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 367 6.4E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SMART SM00388 131 195 2.9E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SUPERFAMILY SSF55874 185 368 2.49E-35 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 195 1.1E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Gene3D G3DSA:1.10.287.130 121 181 8.2E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SUPERFAMILY SSF158472 79 126 2.88E-10 T 16-09-2016 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SUPERFAMILY SSF47384 114 195 2.55E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 SMART SM00304 78 130 5.3E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 PANTHER PTHR24423 72 367 1.6E-66 T 16-09-2016 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 PANTHER PTHR24423 15 21 1.6E-66 T 16-09-2016 Spa2297_RS22315 53bd9c03acf98c393560557abe6b2524 374 Pfam PF00672 HAMP domain 61 126 7.8E-16 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SMART SM00091 188 255 4.0E-4 T 16-09-2016 IPR000014 PAS domain Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 PANTHER PTHR21021:SF19 668 916 1.5E-72 T 16-09-2016 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 720 910 5.8E-44 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF55785 199 293 1.45E-16 T 16-09-2016 IPR000014 PAS domain Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SMART SM00331 693 910 2.4E-71 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF55781 338 476 5.45E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 PANTHER PTHR21021 668 916 1.5E-72 T 16-09-2016 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF55874 82 173 3.56E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Pfam PF13581 Histidine kinase-like ATPase domain 57 167 1.3E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Gene3D G3DSA:3.30.450.20 199 298 1.4E-13 T 16-09-2016 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Pfam PF13492 GAF domain 615 664 3.7E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SMART SM00065 502 672 0.032 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SMART SM00065 337 481 1.6E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Pfam PF08448 PAS fold 199 298 9.3E-9 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 PANTHER PTHR21021 425 486 1.5E-72 T 16-09-2016 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Gene3D G3DSA:3.30.450.40 491 670 6.8E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Pfam PF13185 GAF domain 337 472 2.6E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 PANTHER PTHR21021:SF19 425 486 1.5E-72 T 16-09-2016 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 Gene3D G3DSA:3.30.450.40 336 478 6.4E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF81606 702 910 1.83E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 199 298 3.4E-11 T 16-09-2016 IPR000014 PAS domain Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF55781 618 678 7.99E-10 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS24305 67e205ed1da03d9e1a70d39672cf1a88 916 SUPERFAMILY SSF55781 486 552 7.99E-10 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 PANTHER PTHR11712 23 407 1.7E-41 T 16-09-2016 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 Gene3D G3DSA:1.10.630.10 22 406 3.7E-78 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 SUPERFAMILY SSF48264 11 406 9.95E-57 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 PRINTS PR00359 B-class P450 signature 157 173 2.2E-16 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 PRINTS PR00359 B-class P450 signature 207 229 2.2E-16 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 PRINTS PR00359 B-class P450 signature 299 326 2.2E-16 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01405 4107c922c3f94ae815a61852a362121b 448 PRINTS PR00359 B-class P450 signature 111 122 2.2E-16 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 PANTHER PTHR10066 46 184 2.9E-179 T 16-09-2016 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 Gene3D G3DSA:3.20.20.80 54 344 5.2E-35 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 PANTHER PTHR10066 203 357 2.9E-179 T 16-09-2016 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 PANTHER PTHR10066:SF73 46 184 2.9E-179 T 16-09-2016 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 SUPERFAMILY SSF49785 460 588 8.51E-33 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 134 263 9.9E-7 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 SUPERFAMILY SSF51445 46 344 1.69E-43 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 SMART SM00231 459 587 3.4E-4 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 PANTHER PTHR10066:SF73 203 357 2.9E-179 T 16-09-2016 Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 Pfam PF00754 F5/8 type C domain 468 584 2.8E-27 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS27510 9e50a10ba57239de600f397f3d7c0953 589 Gene3D G3DSA:2.60.120.260 458 588 6.2E-36 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS08995 affd4b804a07938c488adc2a7037e3a6 260 Pfam PF02654 Cobalamin-5-phosphate synthase 13 254 3.4E-44 T 16-09-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS08995 affd4b804a07938c488adc2a7037e3a6 260 PANTHER PTHR34148 1 260 1.1E-53 T 16-09-2016 Spa2297_RS08995 affd4b804a07938c488adc2a7037e3a6 260 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 260 41.002 T 16-09-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS08995 affd4b804a07938c488adc2a7037e3a6 260 PANTHER PTHR34148:SF1 1 260 1.1E-53 T 16-09-2016 Spa2297_RS12510 8995ac2095c9f03383532ad29b470ebe 479 Pfam PF10708 Protein of unknown function (DUF2510) 16 45 2.7E-9 T 16-09-2016 IPR018929 Domain of unknown function DUF2510 Spa2297_RS12510 8995ac2095c9f03383532ad29b470ebe 479 Pfam PF06271 RDD family 323 474 3.1E-24 T 16-09-2016 IPR010432 RDD Spa2297_RS12510 8995ac2095c9f03383532ad29b470ebe 479 PANTHER PTHR36115:SF3 291 477 1.5E-62 T 16-09-2016 Spa2297_RS12510 8995ac2095c9f03383532ad29b470ebe 479 PANTHER PTHR36115 291 477 1.5E-62 T 16-09-2016 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428:SF14 338 387 3.8E-71 T 16-09-2016 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428 338 387 3.8E-71 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 255 2.3E-63 T 16-09-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 Pfam PF02096 60Kd inner membrane protein 38 255 2.4E-58 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428:SF14 174 308 3.8E-71 T 16-09-2016 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428:SF14 8 153 3.8E-71 T 16-09-2016 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428 174 308 3.8E-71 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS16560 a8713b458107900fa22cc3ff8fa6fe87 432 PANTHER PTHR12428 8 153 3.8E-71 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 3.1E-25 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 3.1E-25 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 3.1E-25 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 3.1E-25 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 Gene3D G3DSA:3.40.50.1370 8 147 1.7E-54 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 2.0E-31 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 2.0E-31 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 2.0E-31 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 232 242 2.0E-31 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PRINTS PR00102 Ornithine carbamoyltransferase signature 313 324 2.0E-31 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 Gene3D G3DSA:3.40.50.1370 148 321 1.8E-67 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 161 332 1.9E-49 T 16-09-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PANTHER PTHR11405 8 279 6.2E-187 T 16-09-2016 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PANTHER PTHR11405 298 335 6.2E-187 T 16-09-2016 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PANTHER PTHR11405:SF44 298 335 6.2E-187 T 16-09-2016 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 4.2E-45 T 16-09-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 335 80.757 T 16-09-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 PANTHER PTHR11405:SF44 8 279 6.2E-187 T 16-09-2016 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 334 5.4E-121 T 16-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spa2297_RS25115 e9e74cb9d0b5433c40dae02e1fff9569 335 SUPERFAMILY SSF53671 8 334 1.57E-92 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 52 141 2.6E-15 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 Gene3D G3DSA:2.30.110.10 40 166 5.9E-29 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 PANTHER PTHR30212:SF4 56 183 4.1E-28 T 16-09-2016 Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 28 182 5.7E-58 T 16-09-2016 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 PANTHER PTHR30212 56 183 4.1E-28 T 16-09-2016 Spa2297_RS01705 121ca49d75071f96570b4f6e6e550bd1 187 SUPERFAMILY SSF50475 48 168 8.84E-19 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS01700 4de92213c7cf45382f8de53e18b13326 345 Pfam PF01032 FecCD transport family 28 338 3.1E-84 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01700 4de92213c7cf45382f8de53e18b13326 345 PANTHER PTHR30472:SF31 3 345 1.8E-132 T 16-09-2016 Spa2297_RS01700 4de92213c7cf45382f8de53e18b13326 345 Gene3D G3DSA:1.10.3470.10 13 341 8.3E-96 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01700 4de92213c7cf45382f8de53e18b13326 345 PANTHER PTHR30472 3 345 1.8E-132 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01700 4de92213c7cf45382f8de53e18b13326 345 SUPERFAMILY SSF81345 13 338 1.57E-74 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 Gene3D G3DSA:3.90.1150.10 284 397 2.9E-20 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 SUPERFAMILY SSF53383 10 398 9.31E-110 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 Pfam PF00155 Aminotransferase class I and II 36 392 3.6E-65 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 Gene3D G3DSA:3.40.640.10 49 283 9.1E-85 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 PANTHER PTHR11751:SF301 15 399 5.4E-146 T 16-09-2016 Spa2297_RS17545 a518b592e5b0b9481b8b933e6ad97a45 400 PANTHER PTHR11751 15 399 5.4E-146 T 16-09-2016 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 Pfam PF00037 4Fe-4S binding domain 34 55 1.2E-8 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 SUPERFAMILY SSF54862 3 90 6.7E-22 T 16-09-2016 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 PANTHER PTHR11938 1 89 4.0E-35 T 16-09-2016 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 Gene3D G3DSA:3.30.70.20 3 77 8.4E-20 T 16-09-2016 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.8E-18 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.8E-18 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS21645 9a8136233e6634b82720d5200adf25ea 105 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.8E-18 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 Pfam PF13407 Periplasmic binding protein domain 44 303 1.4E-64 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 SUPERFAMILY SSF53822 41 339 1.36E-65 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 Gene3D G3DSA:3.40.50.2300 36 162 1.5E-30 T 16-09-2016 Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 Gene3D G3DSA:3.40.50.2300 163 339 1.4E-41 T 16-09-2016 Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 PANTHER PTHR30036:SF1 1 352 8.3E-177 T 16-09-2016 Spa2297_RS25265 a9199c7e326be22a8a3f3263fcee2569 366 PANTHER PTHR30036 1 352 8.3E-177 T 16-09-2016 Spa2297_RS03460 02ed546594471a7727618191eb0b36bf 131 Gene3D G3DSA:3.30.429.10 3 126 9.6E-32 T 16-09-2016 Spa2297_RS03460 02ed546594471a7727618191eb0b36bf 131 SUPERFAMILY SSF55331 2 127 3.99E-30 T 16-09-2016 IPR014347 Tautomerase/MIF superfamily Spa2297_RS03460 02ed546594471a7727618191eb0b36bf 131 Pfam PF14552 Tautomerase enzyme 37 119 5.6E-23 T 16-09-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 Spa2297_RS03460 02ed546594471a7727618191eb0b36bf 131 PANTHER PTHR38460:SF1 2 129 7.6E-37 T 16-09-2016 Spa2297_RS03460 02ed546594471a7727618191eb0b36bf 131 PANTHER PTHR38460 2 129 7.6E-37 T 16-09-2016 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 PANTHER PTHR11019:SF75 9 277 1.0E-87 T 16-09-2016 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 SUPERFAMILY SSF46689 174 220 1.79E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 Pfam PF12833 Helix-turn-helix domain 193 270 2.1E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 SUPERFAMILY SSF51215 28 151 4.18E-21 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 Pfam PF02311 AraC-like ligand binding domain 21 148 3.9E-24 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 SMART SM00342 187 269 6.2E-25 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 Gene3D G3DSA:1.10.10.60 174 224 1.3E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 Gene3D G3DSA:1.10.10.60 225 271 1.6E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 PANTHER PTHR11019 9 277 1.0E-87 T 16-09-2016 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 SUPERFAMILY SSF46689 224 272 5.38E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09590 a824b301aa71ed396b50e95865b45a4d 277 Gene3D G3DSA:2.60.120.280 29 151 7.8E-14 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 Pfam PF01264 Chorismate synthase 4 368 3.7E-117 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 16-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 2.1E-141 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 16-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 16-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 PIRSF PIRSF001456 1 386 5.0E-126 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 34.075 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 Gene3D G3DSA:3.60.150.10 4 391 5.9E-154 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 SUPERFAMILY SSF103263 3 390 1.83E-137 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 PANTHER PTHR21085 2 91 1.6E-170 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05650 6cec5298de71ef7dfcc1b3d362de1736 394 PANTHER PTHR21085 109 394 1.6E-170 T 16-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 SUPERFAMILY SSF46689 9 84 6.16E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.8E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.8E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 SUPERFAMILY SSF48498 86 201 9.16E-28 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 PANTHER PTHR30055 5 201 3.9E-86 T 16-09-2016 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 6.2E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 Gene3D G3DSA:1.10.357.10 78 203 2.9E-41 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 PANTHER PTHR30055:SF34 5 201 3.9E-86 T 16-09-2016 Spa2297_RS14770 76f86dfb5e622010a29602decb6b650f 208 Gene3D G3DSA:1.10.10.60 9 72 1.4E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 PANTHER PTHR10366 300 373 1.2E-66 T 16-09-2016 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 PANTHER PTHR10366 23 282 1.2E-66 T 16-09-2016 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 PANTHER PTHR10366:SF418 23 282 1.2E-66 T 16-09-2016 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 PANTHER PTHR10366:SF418 300 373 1.2E-66 T 16-09-2016 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 Gene3D G3DSA:3.40.50.720 23 262 8.8E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 Pfam PF07993 Male sterility protein 58 229 4.2E-37 T 16-09-2016 IPR013120 Male sterility, NAD-binding Reactome: REACT_22258 Spa2297_RS04695 3788cf46c016ee9cd41321f96d25c27a 373 SUPERFAMILY SSF51735 22 282 2.33E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 PANTHER PTHR23542:SF1 24 438 1.1E-148 T 16-09-2016 Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 Gene3D G3DSA:1.20.1250.20 35 218 3.9E-11 T 16-09-2016 Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 SUPERFAMILY SSF103473 34 420 1.4E-28 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 Pfam PF07690 Major Facilitator Superfamily 50 321 1.8E-15 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 Gene3D G3DSA:1.20.1250.20 233 412 8.8E-13 T 16-09-2016 Spa2297_RS13875 7978bed2d1bb9dd4dfa9b4447069884b 438 PANTHER PTHR23542 24 438 1.1E-148 T 16-09-2016 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 SUPERFAMILY SSF142338 3 314 5.89E-86 T 16-09-2016 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 Gene3D G3DSA:3.50.50.60 1 34 9.9E-4 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 PANTHER PTHR30135 1 312 9.1E-140 T 16-09-2016 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 Pfam PF01933 Uncharacterised protein family UPF0052 3 278 1.4E-63 T 16-09-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 309 1.2E-136 T 16-09-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198|UniPathway: UPA00071 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 Gene3D G3DSA:3.40.50.10680 87 317 2.4E-80 T 16-09-2016 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 319 136.469 T 16-09-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198|UniPathway: UPA00071 Spa2297_RS13145 46aa3965823231782ca3ed5232924ec8 319 PANTHER PTHR30135:SF2 1 312 9.1E-140 T 16-09-2016 Spa2297_RS03025 8660d9bd9fe5f8933929c7277f693d97 283 PANTHER PTHR42061:SF1 17 282 6.1E-129 T 16-09-2016 Spa2297_RS03025 8660d9bd9fe5f8933929c7277f693d97 283 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 137 264 4.1E-24 T 16-09-2016 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 Spa2297_RS03025 8660d9bd9fe5f8933929c7277f693d97 283 PANTHER PTHR42061 17 282 6.1E-129 T 16-09-2016 Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 PANTHER PTHR20883 23 274 1.6E-66 T 16-09-2016 Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 SUPERFAMILY SSF51197 32 298 7.87E-60 T 16-09-2016 Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 Gene3D G3DSA:2.60.120.620 34 277 5.8E-50 T 16-09-2016 Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 22 297 3.6E-153 T 16-09-2016 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 KEGG: 00260+1.14.11.-|KEGG: 00361+1.14.11.-|KEGG: 00904+1.14.11.- Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 PANTHER PTHR20883:SF0 23 274 1.6E-66 T 16-09-2016 Spa2297_RS07450 6b69ca6c4ae3fda77c805b0a9d0414f5 298 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 261 1.8E-40 T 16-09-2016 IPR008775 Phytanoyl-CoA dioxygenase Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 PANTHER PTHR23542:SF1 7 425 2.3E-52 T 16-09-2016 Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 PANTHER PTHR23542 7 425 2.3E-52 T 16-09-2016 Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 Gene3D G3DSA:1.20.1250.20 236 396 9.6E-11 T 16-09-2016 Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 Gene3D G3DSA:1.20.1250.20 23 207 1.9E-9 T 16-09-2016 Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 Pfam PF07690 Major Facilitator Superfamily 23 232 5.6E-9 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS22835 4f0a43e1517c06578ca752a95b9d17ed 425 SUPERFAMILY SSF103473 22 404 3.92E-25 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS18125 38b73dd3f722b8feefc1527c8f4240ef 242 PIRSF PIRSF006648 1 242 4.0E-77 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS18125 38b73dd3f722b8feefc1527c8f4240ef 242 Pfam PF01061 ABC-2 type transporter 1 204 4.6E-25 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS18125 38b73dd3f722b8feefc1527c8f4240ef 242 PANTHER PTHR30294 1 242 1.2E-106 T 16-09-2016 Spa2297_RS18125 38b73dd3f722b8feefc1527c8f4240ef 242 PANTHER PTHR30294:SF24 1 242 1.2E-106 T 16-09-2016 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.6E-22 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 16-09-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 PANTHER PTHR15238:SF3 3 53 2.1E-21 T 16-09-2016 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.823 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 Pfam PF00471 Ribosomal protein L33 9 54 2.6E-23 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 SUPERFAMILY SSF57829 4 54 3.66E-20 T 16-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spa2297_RS19560 c5aa9391727b5d814fbe373ba0faa169 54 PANTHER PTHR15238 3 53 2.1E-21 T 16-09-2016 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Gene3D G3DSA:1.50.10.10 321 685 2.2E-124 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 PANTHER PTHR11051:SF8 9 764 2.0E-223 T 16-09-2016 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 PIRSF PIRSF036289 1 766 3.6E-229 T 16-09-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Gene3D G3DSA:2.60.420.10 686 756 2.4E-23 T 16-09-2016 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 1.3E-62 T 16-09-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 PANTHER PTHR11051 9 764 2.0E-223 T 16-09-2016 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Gene3D G3DSA:2.70.98.40 4 270 2.7E-76 T 16-09-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 SUPERFAMILY SSF48208 279 752 9.64E-117 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 704 754 2.1E-17 T 16-09-2016 IPR005194 Glycoside hydrolase family 65, C-terminal Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 700 3.6E-143 T 16-09-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 Spa2297_RS30095 c1699abaaee978f9e545123a0ae913cd 784 SUPERFAMILY SSF74650 4 270 9.42E-67 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS28670 2c273a38bbb67dcf3901ae4a1aed837e 319 Gene3D G3DSA:1.10.3720.10 87 315 1.2E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28670 2c273a38bbb67dcf3901ae4a1aed837e 319 SUPERFAMILY SSF161098 81 305 5.36E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28670 2c273a38bbb67dcf3901ae4a1aed837e 319 PANTHER PTHR30193:SF2 16 319 2.0E-132 T 16-09-2016 Spa2297_RS28670 2c273a38bbb67dcf3901ae4a1aed837e 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 310 1.7E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28670 2c273a38bbb67dcf3901ae4a1aed837e 319 PANTHER PTHR30193 16 319 2.0E-132 T 16-09-2016 Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Gene3D G3DSA:3.40.50.300 430 536 4.7E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Gene3D G3DSA:3.40.50.300 259 398 4.7E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Pfam PF13361 UvrD-like helicase C-terminal domain 672 743 4.5E-15 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Pfam PF13245 Part of AAA domain 275 344 2.2E-12 T 16-09-2016 Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Gene3D G3DSA:3.40.50.300 556 752 1.6E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 PANTHER PTHR11070 252 742 3.3E-45 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 Pfam PF00580 UvrD/REP helicase N-terminal domain 490 537 1.3E-9 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 SUPERFAMILY SSF52540 485 746 8.18E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 SUPERFAMILY SSF52540 255 391 8.18E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22520 7ca394e4a8db19fdcaa5cf659b954730 777 SUPERFAMILY SSF52540 420 447 8.18E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:2.40.30.110 729 802 1.2E-22 T 16-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 SUPERFAMILY SSF51905 10 225 7.34E-64 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 SUPERFAMILY SSF51905 341 423 7.34E-64 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 716 804 2.4E-15 T 16-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Pfam PF01266 FAD dependent oxidoreductase 11 377 2.8E-49 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.30.1360.120 591 686 2.1E-20 T 16-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.30.1360.120 433 519 1.9E-11 T 16-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 SUPERFAMILY SSF54373 225 340 3.37E-30 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Pfam PF01571 Aminomethyltransferase folate-binding domain 438 709 2.6E-71 T 16-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 PANTHER PTHR13847 11 457 7.8E-172 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.30.9.10 225 340 3.2E-51 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.30.9.10 91 144 3.2E-51 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.50.50.60 145 224 3.5E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.50.50.60 9 81 3.5E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.50.50.60 341 421 3.5E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 SUPERFAMILY SSF103025 430 730 2.2E-92 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Gene3D G3DSA:3.30.70.1400 520 585 1.2E-17 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 PANTHER PTHR13847:SF181 11 457 7.8E-172 T 16-09-2016 Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 Pfam PF16350 FAD dependent oxidoreductase central domain 380 435 3.4E-20 T 16-09-2016 IPR032503 FAD dependent oxidoreductase, central domain Spa2297_RS05215 f2cbad93d0ba3d5a5b61eb31c2801910 817 SUPERFAMILY SSF101790 731 816 5.89E-23 T 16-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 3.5E-33 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 PANTHER PTHR11695:SF429 12 329 1.9E-111 T 16-09-2016 Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 Pfam PF00107 Zinc-binding dehydrogenase 171 288 3.3E-12 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 Gene3D G3DSA:3.40.50.720 163 277 3.2E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 SUPERFAMILY SSF51735 138 299 8.01E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 SUPERFAMILY SSF50129 1 167 6.39E-52 T 16-09-2016 IPR011032 GroES-like Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 Gene3D G3DSA:3.90.180.10 1 162 2.1E-54 T 16-09-2016 IPR011032 GroES-like Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 PANTHER PTHR11695 12 329 1.9E-111 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS07590 9a20e5f734120117e1a2c52ac5a6ed45 329 SMART SM00829 4 327 9.1E-4 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.361 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 Gene3D G3DSA:3.90.226.10 6 194 1.4E-68 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 Pfam PF00574 Clp protease 15 195 7.0E-69 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PANTHER PTHR10381 6 200 8.8E-126 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PANTHER PTHR10381:SF7 6 200 8.8E-126 T 16-09-2016 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 1.0E-39 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 1.0E-39 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 1.0E-39 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 1.0E-39 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 1.0E-39 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02285 7da346be4bf5cffc9e36266166d58438 200 SUPERFAMILY SSF52096 13 194 1.19E-57 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 SMART SM00341 214 294 1.4E-20 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 SMART SM00474 9 175 3.1E-40 T 16-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 Gene3D G3DSA:3.30.420.10 13 182 4.4E-6 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 SUPERFAMILY SSF53098 9 212 4.98E-50 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 Gene3D G3DSA:1.10.150.80 223 274 2.7E-5 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 Pfam PF00570 HRDC domain 217 274 3.3E-14 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 SUPERFAMILY SSF47819 195 305 1.66E-23 T 16-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 PANTHER PTHR12124 32 313 2.0E-53 T 16-09-2016 Spa2297_RS25345 7a01d2e1dc979091e9ad6cdfb0b3b51d 396 Pfam PF01612 3'-5' exonuclease 15 175 5.0E-35 T 16-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 327 376 5.5E-11 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Gene3D G3DSA:3.30.450.20 218 318 3.1E-4 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 531 2.0E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PANTHER PTHR24423:SF523 148 162 1.4E-64 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PANTHER PTHR24423 195 529 1.4E-64 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 SUPERFAMILY SSF55785 228 329 6.51E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 SMART SM00387 424 536 1.4E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 SUPERFAMILY SSF103190 43 168 4.32E-13 T 16-09-2016 IPR029151 Periplasmic sensor domain-like Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PANTHER PTHR24423 148 162 1.4E-64 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 SUPERFAMILY SSF55890 334 376 5.1E-10 T 16-09-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 SUPERFAMILY SSF55874 392 531 4.06E-24 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Pfam PF17203 Single cache domain 3 38 173 8.7E-13 T 16-09-2016 IPR033463 Single cache domain 3 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PANTHER PTHR24423:SF523 195 529 1.4E-64 T 16-09-2016 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Gene3D G3DSA:1.10.287.130 319 379 1.8E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 2.6E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 515 2.6E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 493 2.6E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Gene3D G3DSA:3.30.565.10 391 536 3.1E-26 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03835 1809ba4e5b228c1d311bf134002fe086 547 Gene3D G3DSA:3.30.450.20 34 166 2.6E-19 T 16-09-2016 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 SUPERFAMILY SSF74650 413 668 4.92E-83 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 416 658 1.2E-83 T 16-09-2016 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Gene3D G3DSA:2.70.98.10 427 667 1.3E-85 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 52 374 1.3E-101 T 16-09-2016 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Gene3D G3DSA:2.60.220.10 671 781 1.7E-31 T 16-09-2016 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Gene3D G3DSA:1.50.10.100 43 426 2.6E-105 T 16-09-2016 IPR012329 Polysaccharide lyase family 8, N-terminal GO:0005975|GO:0016837 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 SUPERFAMILY SSF48230 43 411 2.75E-109 T 16-09-2016 IPR008929 Chondroitin AC/alginate lyase Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 PANTHER PTHR38481:SF1 18 783 3.9E-208 T 16-09-2016 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 PANTHER PTHR38481 18 783 3.9E-208 T 16-09-2016 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 673 734 2.4E-15 T 16-09-2016 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 Spa2297_RS23440 2ba54133f41eff8a47fff61d1e1efd6e 783 SUPERFAMILY SSF49863 671 782 1.96E-25 T 16-09-2016 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 Gene3D G3DSA:2.60.40.420 39 181 1.9E-24 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 Gene3D G3DSA:2.60.40.420 196 309 1.6E-20 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 Pfam PF07732 Multicopper oxidase 73 182 1.8E-12 T 16-09-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 SUPERFAMILY SSF49503 72 185 1.87E-17 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 Pfam PF07731 Multicopper oxidase 201 306 9.4E-14 T 16-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 ProSitePatterns PS00080 Multicopper oxidases signature 2. 287 298 - T 16-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 Spa2297_RS27935 3d3f97976e0588997cacc566b8d75e5d 335 SUPERFAMILY SSF49503 189 309 4.95E-23 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 SUPERFAMILY SSF51735 13 341 3.51E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 PANTHER PTHR10366 298 349 3.1E-94 T 16-09-2016 Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 PANTHER PTHR10366 15 282 3.1E-94 T 16-09-2016 Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 Pfam PF01370 NAD dependent epimerase/dehydratase family 16 252 4.5E-22 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 PANTHER PTHR10366:SF267 15 282 3.1E-94 T 16-09-2016 Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 PANTHER PTHR10366:SF267 298 349 3.1E-94 T 16-09-2016 Spa2297_RS28775 8dfb4f15d2d3d339b98d8f15bdcb81de 355 Gene3D G3DSA:3.40.50.720 15 340 6.8E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SUPERFAMILY SSF47781 414 507 4.82E-43 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SUPERFAMILY SSF47781 538 630 4.82E-43 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 PANTHER PTHR23389 530 579 1.7E-178 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:1.10.287.610 10 77 1.0E-27 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 503 6.8E-178 T 16-09-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 PANTHER PTHR23389:SF9 4 499 1.7E-178 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:3.30.470.30 130 263 3.9E-50 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 342 357 - T 16-09-2016 IPR033136 NAD-dependent DNA ligase, conserved site Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SMART SM00532 15 460 1.7E-267 T 16-09-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Hamap MF_01588 DNA ligase [ligA]. 14 715 51.576 T 16-09-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:1.10.150.20 447 503 8.3E-8 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 15 329 1.3E-126 T 16-09-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SUPERFAMILY SSF56091 14 326 2.47E-114 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 641 712 1.0E-14 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:2.40.50.140 331 401 5.5E-27 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 PANTHER PTHR23389 4 499 1.7E-178 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SUPERFAMILY SSF52113 640 718 1.23E-18 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 PIRSF PIRSF001604 7 720 6.0E-248 T 16-09-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:3.40.50.10190 641 719 3.5E-24 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 16-09-2016 IPR018239 NAD-dependent DNA ligase, active site Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 PANTHER PTHR23389:SF9 530 579 1.7E-178 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Pfam PF12826 Helix-hairpin-helix motif 557 620 3.1E-20 T 16-09-2016 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SMART SM00292 641 718 1.8E-12 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 333 409 5.0E-29 T 16-09-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 SUPERFAMILY SSF50249 329 411 1.88E-24 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 418 446 2.2E-7 T 16-09-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 Spa2297_RS23250 ef901ab35a11d30fe31ede2497b49f9a 731 Gene3D G3DSA:1.10.150.20 551 631 2.5E-26 T 16-09-2016 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Gene3D G3DSA:1.10.1780.10 1 153 9.9E-44 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 1.1E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 1.1E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 1.1E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 1.1E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SUPERFAMILY SSF81923 4 160 4.71E-42 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SUPERFAMILY SSF52540 164 553 1.35E-93 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 16-09-2016 IPR028299 ClpA/B, conserved site 2 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SMART SM00382 605 758 1.0E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SMART SM00382 203 348 3.6E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PANTHER PTHR11638:SF18 1 880 0.0 T 16-09-2016 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Gene3D G3DSA:3.40.50.300 164 347 4.5E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.5E-13 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 2.3E-11 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Gene3D G3DSA:3.40.50.300 560 787 4.3E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 PANTHER PTHR11638 1 880 0.0 T 16-09-2016 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Gene3D G3DSA:1.10.8.60 788 873 1.6E-31 T 16-09-2016 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 16-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SUPERFAMILY SSF52540 554 867 2.19E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 340 3.9E-11 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 770 5.9E-55 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 856 9.0E-25 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 Gene3D G3DSA:1.10.8.60 348 432 2.3E-35 T 16-09-2016 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 865 0.0 T 16-09-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 Spa2297_RS14040 870d10105d5c16cfde3c113dc0135286 880 SMART SM01086 776 865 1.2E-34 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS11915 fdd6464fee283169f55cc5bbb9aefe9b 321 Pfam PF14378 PAP2 superfamily 53 240 3.3E-61 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS11915 fdd6464fee283169f55cc5bbb9aefe9b 321 PANTHER PTHR31310 15 259 5.5E-45 T 16-09-2016 Spa2297_RS11915 fdd6464fee283169f55cc5bbb9aefe9b 321 PANTHER PTHR31310:SF6 15 259 5.5E-45 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 Gene3D G3DSA:1.20.1640.10 132 338 4.7E-29 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 Gene3D G3DSA:1.20.1640.10 478 686 4.2E-24 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 PANTHER PTHR33406:SF2 6 692 1.6E-168 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 SUPERFAMILY SSF82866 120 334 5.1E-31 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 SUPERFAMILY SSF82866 466 685 1.57E-29 T 16-09-2016 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 Pfam PF03176 MMPL family 45 364 9.5E-73 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 Pfam PF03176 MMPL family 396 691 1.8E-51 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS29500 172889bb82288348071c2f659881506d 697 PANTHER PTHR33406 6 692 1.6E-168 T 16-09-2016 Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 Gene3D G3DSA:3.40.50.720 1 249 9.6E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0012 T 16-09-2016 Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 1.0E-55 T 16-09-2016 Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 SUPERFAMILY SSF51735 6 249 3.75E-73 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PANTHER PTHR24322 12 142 3.1E-51 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PANTHER PTHR24322 158 193 3.1E-51 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00010 4eaa7ccc404b9ac7d94f37b7e648794f 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 Pfam PF00072 Response regulator receiver domain 7 119 1.5E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 PANTHER PTHR26402:SF563 5 129 3.2E-54 T 16-09-2016 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 SMART SM00448 5 119 7.4E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 PANTHER PTHR26402 5 129 3.2E-54 T 16-09-2016 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 Gene3D G3DSA:3.40.50.2300 3 129 3.7E-36 T 16-09-2016 Spa2297_RS24315 fa7e5899520bd6ba9e87525a3d175085 224 SUPERFAMILY SSF52172 3 144 1.08E-37 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 PANTHER PTHR24221 5 375 1.0E-139 T 16-09-2016 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 SUPERFAMILY SSF90123 21 328 1.83E-44 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 Gene3D G3DSA:3.40.50.300 394 582 4.7E-35 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 PANTHER PTHR24221:SF161 391 585 1.0E-139 T 16-09-2016 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 Pfam PF00664 ABC transporter transmembrane region 105 303 5.4E-22 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 Gene3D G3DSA:1.20.1560.10 22 327 1.9E-34 T 16-09-2016 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 PANTHER PTHR24221 391 585 1.0E-139 T 16-09-2016 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 Pfam PF00005 ABC transporter 416 505 2.0E-10 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 SUPERFAMILY SSF52540 390 573 3.71E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04095 d4959bf442eb31daea5ecff87b7eca80 634 PANTHER PTHR24221:SF161 5 375 1.0E-139 T 16-09-2016 Spa2297_RS12010 854e860d3d2bc0004dc2c30f1cbdd938 202 Gene3D G3DSA:3.40.430.10 4 200 4.8E-38 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS12010 854e860d3d2bc0004dc2c30f1cbdd938 202 Pfam PF01872 RibD C-terminal domain 5 178 1.4E-20 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS12010 854e860d3d2bc0004dc2c30f1cbdd938 202 PANTHER PTHR38011:SF1 2 202 5.2E-52 T 16-09-2016 Spa2297_RS12010 854e860d3d2bc0004dc2c30f1cbdd938 202 PANTHER PTHR38011 2 202 5.2E-52 T 16-09-2016 Spa2297_RS12010 854e860d3d2bc0004dc2c30f1cbdd938 202 SUPERFAMILY SSF53597 5 185 4.97E-24 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 PANTHER PTHR30146 11 341 8.2E-139 T 16-09-2016 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 SUPERFAMILY SSF47413 11 60 6.48E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 Gene3D G3DSA:3.40.50.2300 174 341 2.2E-58 T 16-09-2016 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 Gene3D G3DSA:1.10.260.40 11 60 8.0E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 Pfam PF13377 Periplasmic binding protein-like domain 174 340 1.3E-40 T 16-09-2016 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 SMART SM00354 11 76 4.0E-10 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 56 4.2E-15 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 SUPERFAMILY SSF53822 67 342 5.14E-74 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 Gene3D G3DSA:3.40.50.2300 67 173 3.9E-20 T 16-09-2016 Spa2297_RS00705 f93ef6aab20b659167dfcb1b3d7de63a 346 PANTHER PTHR30146:SF43 11 341 8.2E-139 T 16-09-2016 Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00722 55 206 1.2E-8 T 16-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SUPERFAMILY SSF51126 23 351 1.09E-38 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 Pfam PF13229 Right handed beta helix region 90 236 2.2E-14 T 16-09-2016 Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 Pfam PF13229 Right handed beta helix region 242 348 1.1E-6 T 16-09-2016 Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 240 275 600.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 111 133 360.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 190 211 74.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 157 179 2.9 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 212 233 170.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 SMART SM00710 276 303 520.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01505 6a87580a998be64f130df401009eb897 356 Gene3D G3DSA:2.160.20.10 32 347 2.2E-28 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS25870 07becdb98814b050eb7240ac3186ed4a 116 Pfam PF13601 Winged helix DNA-binding domain 16 94 1.5E-25 T 16-09-2016 IPR027395 Winged helix DNA-binding domain Spa2297_RS25870 07becdb98814b050eb7240ac3186ed4a 116 PANTHER PTHR37318 1 99 2.1E-19 T 16-09-2016 Spa2297_RS25870 07becdb98814b050eb7240ac3186ed4a 116 SUPERFAMILY SSF46785 9 96 7.44E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25870 07becdb98814b050eb7240ac3186ed4a 116 Gene3D G3DSA:1.10.10.10 7 95 1.9E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19175 253f408afb8306cf670ddd92739649c0 171 PANTHER PTHR13256 8 148 4.9E-43 T 16-09-2016 Spa2297_RS19175 253f408afb8306cf670ddd92739649c0 171 PANTHER PTHR13256:SF19 8 148 4.9E-43 T 16-09-2016 Spa2297_RS19175 253f408afb8306cf670ddd92739649c0 171 SUPERFAMILY SSF55729 8 150 1.06E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS19175 253f408afb8306cf670ddd92739649c0 171 Pfam PF13302 Acetyltransferase (GNAT) domain 9 147 1.3E-25 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS19175 253f408afb8306cf670ddd92739649c0 171 Gene3D G3DSA:3.40.630.30 8 166 3.4E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22440 ac193b330c280d146bccc1c89c4ff535 248 Pfam PF13628 Domain of unknown function (DUF4142) 54 187 1.1E-11 T 16-09-2016 IPR025419 Domain of unknown function DUF4142 Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 Gene3D G3DSA:3.40.50.720 5 245 3.0E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PANTHER PTHR24322:SF406 155 186 2.4E-64 T 16-09-2016 Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PANTHER PTHR24322 8 138 2.4E-64 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 6.6E-56 T 16-09-2016 Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.6E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 7.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PANTHER PTHR24322:SF406 8 138 2.4E-64 T 16-09-2016 Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 PANTHER PTHR24322 155 186 2.4E-64 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04880 d46fccba3100890d6eccfc62c2ad15ef 246 SUPERFAMILY SSF51735 6 245 3.13E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PANTHER PTHR22845:SF4 233 595 1.3E-72 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SUPERFAMILY SSF48452 39 200 1.28E-29 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Pfam PF13424 Tetratricopeptide repeat 776 845 1.0E-7 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SUPERFAMILY SSF52540 240 494 1.15E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Pfam PF00515 Tetratricopeptide repeat 736 764 4.6E-7 T 16-09-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:1.25.40.10 671 683 8.3E-24 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:1.25.40.10 753 926 8.3E-24 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PANTHER PTHR22845 84 202 1.3E-72 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PANTHER PTHR22845:SF4 84 202 1.3E-72 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Pfam PF00931 NB-ARC domain 274 493 3.8E-15 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SMART SM00028 46 79 290.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SMART SM00028 894 927 58.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SMART SM00028 814 847 0.17 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SMART SM00028 734 767 5.9E-5 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SUPERFAMILY SSF48452 733 923 9.87E-21 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:3.40.50.300 260 365 1.7E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SMART SM01043 41 185 4.0E-39 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PANTHER PTHR22845 233 595 1.3E-72 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:1.25.40.10 131 167 8.0E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:1.25.40.10 44 75 8.0E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Gene3D G3DSA:1.25.40.10 733 752 8.0E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PRINTS PR00364 Disease resistance protein signature 272 287 1.5E-7 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PRINTS PR00364 Disease resistance protein signature 349 363 1.5E-7 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 PRINTS PR00364 Disease resistance protein signature 433 447 1.5E-7 T 16-09-2016 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 SUPERFAMILY SSF48452 669 763 9.87E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03005 de57ac9e1aa12f73036b7e9da865e8ab 950 Pfam PF03704 Bacterial transcriptional activator domain 41 185 1.4E-35 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS17430 fc0f004fad441c95ce4b7746cc62da72 70 SUPERFAMILY SSF46955 4 59 2.01E-5 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS17430 fc0f004fad441c95ce4b7746cc62da72 70 Pfam PF12728 Helix-turn-helix domain 4 53 1.1E-12 T 16-09-2016 Spa2297_RS17430 fc0f004fad441c95ce4b7746cc62da72 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 51 4.3E-18 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS08500 db7532cf883c3d8022ced46680d9af25 213 Hamap MF_01197 Cell division protein SepF [sepF]. 2 204 22.529 T 16-09-2016 IPR023052 Cell division protein SepF GO:0090529 Spa2297_RS08500 db7532cf883c3d8022ced46680d9af25 213 PANTHER PTHR35798 38 212 1.7E-41 T 16-09-2016 Spa2297_RS08500 db7532cf883c3d8022ced46680d9af25 213 Pfam PF04472 Protein of unknown function (DUF552) 125 196 3.6E-27 T 16-09-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 Spa2297_RS08500 db7532cf883c3d8022ced46680d9af25 213 PANTHER PTHR35798:SF1 38 212 1.7E-41 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PANTHER PTHR11573:SF6 47 795 0.0 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Pfam PF02867 Ribonucleotide reductase, barrel domain 229 752 2.4E-172 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 149 225 6.7E-20 T 16-09-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 SUPERFAMILY SSF51998 228 656 3.97E-173 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 SUPERFAMILY SSF51998 687 757 3.97E-173 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 596 618 - T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Gene3D G3DSA:3.20.70.20 607 652 1.7E-77 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Gene3D G3DSA:3.20.70.20 401 562 1.7E-77 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Gene3D G3DSA:3.20.70.20 153 351 1.7E-77 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 Gene3D G3DSA:3.20.70.20 713 749 1.7E-77 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PANTHER PTHR11573 47 795 0.0 T 16-09-2016 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 SUPERFAMILY SSF48168 32 227 9.81E-44 T 16-09-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 542 565 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 476 499 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 607 634 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 305 324 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 514 536 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 PRINTS PR01183 Ribonucleotide reductase large chain signature 437 448 3.4E-48 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS22115 2280f491c2c3a334c7e1a34b0f924d14 795 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 152 756 1.4E-220 T 16-09-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 Spa2297_RS31265 60b18182d65d15c5af5373a1a56a5039 352 SUPERFAMILY SSF46785 263 330 1.13E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31265 60b18182d65d15c5af5373a1a56a5039 352 SMART SM00418 261 329 8.6E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS31265 60b18182d65d15c5af5373a1a56a5039 352 Pfam PF12840 Helix-turn-helix domain 263 313 8.6E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31265 60b18182d65d15c5af5373a1a56a5039 352 Gene3D G3DSA:1.10.10.10 262 321 1.7E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 Gene3D G3DSA:3.40.190.10 277 311 4.7E-38 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 Gene3D G3DSA:3.40.190.10 6 133 4.7E-38 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 SUPERFAMILY SSF53850 29 344 1.57E-55 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 PANTHER PTHR30006 27 349 3.1E-59 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 Pfam PF13343 Bacterial extracellular solute-binding protein 86 336 3.2E-29 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 Gene3D G3DSA:3.40.190.10 137 276 1.7E-26 T 16-09-2016 Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 PIRSF PIRSF002825 3 347 9.9E-48 T 16-09-2016 IPR026045 Ferric binding protein Spa2297_RS12160 8c900561ecda413f876c6bfda1c377c2 350 PANTHER PTHR30006:SF8 27 349 3.1E-59 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 18 327 1.2E-74 T 16-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 PANTHER PTHR21299 9 227 5.1E-111 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 Hamap MF_00158 Pantothenate synthetase [panC]. 7 327 38.49 T 16-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 PANTHER PTHR21299 270 328 5.1E-111 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 PANTHER PTHR21299:SF1 270 328 5.1E-111 T 16-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 Pfam PF02569 Pantoate-beta-alanine ligase 20 325 1.9E-87 T 16-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 SUPERFAMILY SSF52374 269 329 1.37E-6 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 Gene3D G3DSA:3.40.50.620 17 177 8.1E-67 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 PANTHER PTHR21299:SF1 9 227 5.1E-111 T 16-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 SUPERFAMILY SSF52374 15 227 8.8E-82 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 Gene3D G3DSA:3.30.1300.10 270 330 4.0E-32 T 16-09-2016 Spa2297_RS18285 fe624544a822f161e0be54ddaf887df3 333 Gene3D G3DSA:3.30.1300.10 179 223 4.0E-32 T 16-09-2016 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 PANTHER PTHR20941 1 277 1.6E-194 T 16-09-2016 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 Gene3D G3DSA:3.20.20.20 12 274 3.5E-85 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 Pfam PF00809 Pterin binding enzyme 17 257 1.2E-65 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 PANTHER PTHR20941:SF8 1 277 1.6E-194 T 16-09-2016 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 SUPERFAMILY SSF51717 4 276 4.45E-82 T 16-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 2.2E-82 T 16-09-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 Spa2297_RS21675 2ef21ea1d054af013178bf1a5838da33 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS25585 7936024698554c4148a95e3c619f063d 139 SUPERFAMILY SSF103196 7 132 4.36E-32 T 16-09-2016 Spa2297_RS25585 7936024698554c4148a95e3c619f063d 139 PANTHER PTHR36222 1 138 5.8E-52 T 16-09-2016 Spa2297_RS25585 7936024698554c4148a95e3c619f063d 139 Gene3D G3DSA:3.30.450.30 7 130 6.7E-29 T 16-09-2016 Spa2297_RS25585 7936024698554c4148a95e3c619f063d 139 SMART SM00960 13 103 3.7E-27 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS25585 7936024698554c4148a95e3c619f063d 139 Pfam PF03259 Roadblock/LC7 domain 13 103 5.5E-25 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 PANTHER PTHR30154 1 143 2.2E-51 T 16-09-2016 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.3E-17 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 SUPERFAMILY SSF54909 61 143 7.11E-18 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 Gene3D G3DSA:1.10.10.10 1 52 2.9E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.1E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.1E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.1E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 7.1E-19 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 SUPERFAMILY SSF46785 1 60 1.32E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 SMART SM00344 1 108 7.9E-39 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 Gene3D G3DSA:3.30.70.920 54 144 3.1E-23 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS18855 f90c948bd2fbdb4ad31291d129be6fb6 151 PANTHER PTHR30154:SF2 1 143 2.2E-51 T 16-09-2016 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 SUPERFAMILY SSF51735 2 163 3.25E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 Gene3D G3DSA:3.90.110.10 164 439 7.2E-93 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 6.5E-38 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PANTHER PTHR32092 1 302 2.1E-175 T 16-09-2016 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 Pfam PF02056 Family 4 glycosyl hydrolase 3 180 3.0E-42 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 421 6.9E-45 T 16-09-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PANTHER PTHR32092 321 439 2.1E-175 T 16-09-2016 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PANTHER PTHR32092:SF5 1 302 2.1E-175 T 16-09-2016 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 Gene3D G3DSA:3.40.50.720 2 163 8.6E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 PANTHER PTHR32092:SF5 321 439 2.1E-175 T 16-09-2016 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 135 165 - T 16-09-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 SUPERFAMILY SSF56327 166 297 8.63E-63 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS27725 c8654e24d43432bc98ab8ac408a72b64 445 SUPERFAMILY SSF56327 324 440 8.63E-63 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 Pfam PF08281 Sigma-70, region 4 111 161 2.8E-11 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 Gene3D G3DSA:1.10.10.10 109 164 1.4E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 SUPERFAMILY SSF88659 86 163 3.92E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 PANTHER PTHR30173 1 294 4.0E-117 T 16-09-2016 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 Gene3D G3DSA:3.10.450.50 174 294 1.4E-11 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 SUPERFAMILY SSF88946 11 91 1.29E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 162 7.8E-13 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 Gene3D G3DSA:1.10.1740.10 11 76 2.6E-13 T 16-09-2016 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 Pfam PF04542 Sigma-70 region 2 11 74 5.8E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 PANTHER PTHR30173:SF25 1 294 4.0E-117 T 16-09-2016 Spa2297_RS17260 8b771c227badc40177a08011e0cc8dfb 314 SUPERFAMILY SSF54427 174 294 9.79E-12 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748 69 219 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748:SF4 245 344 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748:SF4 69 219 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748:SF4 361 401 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 Gene3D G3DSA:3.40.50.300 69 175 5.1E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 69 175 3.2E-5 T 16-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 SMART SM00833 271 387 8.3E-37 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748 245 344 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 PANTHER PTHR13748 361 401 2.3E-66 T 16-09-2016 Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 Gene3D G3DSA:3.30.1220.10 264 387 7.3E-8 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 SUPERFAMILY SSF90002 361 387 5.62E-10 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 SUPERFAMILY SSF90002 271 334 5.62E-10 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS18080 5c501f3313f1e767c3c24df237e2c0d3 413 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 272 387 8.8E-20 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670:SF1 1 384 0.0 T 16-09-2016 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670:SF1 426 661 0.0 T 16-09-2016 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670:SF1 677 722 0.0 T 16-09-2016 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Gene3D G3DSA:3.40.1060.10 241 358 3.7E-36 T 16-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 SUPERFAMILY SSF52016 641 905 4.51E-84 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Gene3D G3DSA:3.30.499.10 28 240 3.7E-78 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 ProSitePatterns PS01244 Aconitase family signature 2. 503 516 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 ProSitePatterns PS00450 Aconitase family signature 1. 437 453 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Pfam PF00694 Aconitase C-terminal domain 702 835 3.1E-42 T 16-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670 677 722 0.0 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 363 377 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 503 516 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 284 297 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 141 154 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 441 452 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 194 207 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 208 223 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 270 283 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PRINTS PR00415 Aconitase family signature 165 173 5.1E-42 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Gene3D G3DSA:3.20.19.10 647 905 1.6E-75 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Gene3D G3DSA:3.30.499.10 360 384 2.1E-64 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Gene3D G3DSA:3.30.499.10 429 584 2.1E-64 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670:SF1 767 908 0.0 T 16-09-2016 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670 767 908 0.0 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670 1 384 0.0 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 PANTHER PTHR11670 426 661 0.0 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 SUPERFAMILY SSF53732 4 637 2.09E-221 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 Pfam PF00330 Aconitase family (aconitate hydratase) 64 572 4.3E-182 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS25230 500d350876aca41d4f3006cb8f795c04 908 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 905 0.0 T 16-09-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 Spa2297_RS19415 aa2afc42657e958db71ffd041942caf5 284 PANTHER PTHR14194:SF73 1 280 4.9E-96 T 16-09-2016 Spa2297_RS19415 aa2afc42657e958db71ffd041942caf5 284 PANTHER PTHR14194 1 280 4.9E-96 T 16-09-2016 Spa2297_RS19415 aa2afc42657e958db71ffd041942caf5 284 SUPERFAMILY SSF51735 3 256 1.69E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19415 aa2afc42657e958db71ffd041942caf5 284 Gene3D G3DSA:3.40.50.720 1 217 6.2E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19415 aa2afc42657e958db71ffd041942caf5 284 Pfam PF13460 NAD(P)H-binding 7 183 2.7E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 Pfam PF07690 Major Facilitator Superfamily 26 416 1.2E-45 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 PANTHER PTHR23501:SF48 7 536 5.6E-213 T 16-09-2016 Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 SUPERFAMILY SSF103473 486 516 2.01E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 SUPERFAMILY SSF103473 17 209 2.01E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 SUPERFAMILY SSF103473 256 426 2.01E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 Gene3D G3DSA:1.20.1250.20 487 517 2.4E-19 T 16-09-2016 Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 Gene3D G3DSA:1.20.1250.20 19 200 2.5E-29 T 16-09-2016 Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 Gene3D G3DSA:1.20.1250.20 271 427 2.4E-19 T 16-09-2016 Spa2297_RS25030 b14583ccb37f700d0c623d4f3477e5ec 536 PANTHER PTHR23501 7 536 5.6E-213 T 16-09-2016 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Gene3D G3DSA:1.20.1530.10 9 248 6.0E-107 T 16-09-2016 IPR023171 Na/H antiporter domain Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Gene3D G3DSA:1.20.1530.10 281 411 6.0E-107 T 16-09-2016 IPR023171 Na/H antiporter domain Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Pfam PF06965 Na+/H+ antiporter 1 11 410 2.2E-111 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 9 424 17.424 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 PANTHER PTHR30341:SF0 8 247 2.2E-152 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Gene3D G3DSA:3.40.30.10 442 608 8.6E-47 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 PANTHER PTHR30341 270 427 2.2E-152 T 16-09-2016 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 PANTHER PTHR30341 8 247 2.2E-152 T 16-09-2016 Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 Pfam PF13462 Thioredoxin 446 605 1.4E-26 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 SUPERFAMILY SSF52833 442 604 4.78E-42 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS00855 43e2b86e7d0715aee576f3c359e64e5a 614 PANTHER PTHR30341:SF0 270 427 2.2E-152 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Pfam PF02780 Transketolase, C-terminal domain 496 611 3.8E-29 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 4.4E-108 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 16-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 619 5.8E-182 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 PANTHER PTHR11624 17 211 9.7E-257 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 PANTHER PTHR11624:SF20 17 211 9.7E-257 T 16-09-2016 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 PANTHER PTHR11624 238 631 9.7E-257 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 SUPERFAMILY SSF52518 3 346 2.32E-68 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 PANTHER PTHR11624:SF20 238 631 9.7E-257 T 16-09-2016 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Gene3D G3DSA:3.40.50.920 499 616 3.2E-27 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Gene3D G3DSA:3.40.50.970 299 478 2.0E-50 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Gene3D G3DSA:3.40.50.970 4 188 1.4E-48 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Gene3D G3DSA:3.40.50.970 236 298 1.4E-48 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 SUPERFAMILY SSF52922 497 616 6.28E-26 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 SMART SM00861 316 481 4.6E-48 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 SUPERFAMILY SSF52518 296 477 1.26E-49 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 620 40.549 T 16-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS28195 fc10de4426e902a8a8f3b0bb18b0ced4 641 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 3.4E-35 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PRINTS PR00400 Tetracycline repressor protein signature 26 49 6.4E-11 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PRINTS PR00400 Tetracycline repressor protein signature 79 98 6.4E-11 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PRINTS PR00400 Tetracycline repressor protein signature 188 202 6.4E-11 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PANTHER PTHR30055:SF36 1 127 4.5E-38 T 16-09-2016 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 SUPERFAMILY SSF48498 78 207 7.34E-27 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 Gene3D G3DSA:1.10.357.10 2 208 3.4E-61 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 SUPERFAMILY SSF46689 2 67 2.72E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 205 1.2E-14 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.0E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06670 3b2dfe3261572e68c46ce07349f05287 213 PANTHER PTHR30055 1 127 4.5E-38 T 16-09-2016 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 SMART SM01060 9 390 1.2E-276 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PANTHER PTHR11465 6 488 7.8E-272 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 Pfam PF00199 Catalase 9 386 5.4E-184 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 Gene3D G3DSA:2.40.180.10 5 358 1.1E-174 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PIRSF PIRSF038928 1 486 5.5E-232 T 16-09-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 ProSitePatterns PS00438 Catalase proximal active site signature. 45 61 - T 16-09-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 SUPERFAMILY SSF56634 5 490 1.57E-200 T 16-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 16-09-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 Pfam PF06628 Catalase-related immune-responsive 418 480 3.5E-18 T 16-09-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 84 102 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 22 45 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 124 142 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 289 316 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 105 122 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS00890 2b48982c5e5fe1b79ce8e1025fef496e 506 PRINTS PR00067 Catalase signature 321 347 6.7E-66 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Gene3D G3DSA:3.30.43.10 4 91 2.0E-22 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 SUPERFAMILY SSF56176 2 248 1.23E-61 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 SUPERFAMILY SSF46548 514 603 7.32E-7 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Gene3D G3DSA:3.30.465.10 92 248 1.3E-35 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Pfam PF02913 FAD linked oxidases, C-terminal domain 248 481 2.0E-52 T 16-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Pfam PF13183 4Fe-4S dicluster domain 519 599 6.8E-9 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 PANTHER PTHR11748:SF35 1 178 7.9E-142 T 16-09-2016 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 PANTHER PTHR11748:SF35 215 531 7.9E-142 T 16-09-2016 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Gene3D G3DSA:1.10.1060.10 473 612 5.3E-11 T 16-09-2016 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 PANTHER PTHR11748 1 178 7.9E-142 T 16-09-2016 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 PANTHER PTHR11748 215 531 7.9E-142 T 16-09-2016 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 SUPERFAMILY SSF55103 251 486 1.6E-54 T 16-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Gene3D G3DSA:1.10.45.10 445 472 1.8E-4 T 16-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Spa2297_RS14550 0afdf8e857cb424b940346a337d93127 959 Pfam PF01565 FAD binding domain 37 174 6.2E-42 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 SMART SM00347 35 133 6.2E-18 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 Gene3D G3DSA:1.10.10.10 5 145 9.6E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 SUPERFAMILY SSF46785 9 145 2.37E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 Pfam PF01047 MarR family 49 98 2.8E-14 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS10095 e6ac3f60f054dcf4ef47ce75e6a20345 146 PANTHER PTHR33164 12 146 9.8E-22 T 16-09-2016 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 152 161 - T 16-09-2016 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Gene3D G3DSA:1.10.10.10 446 502 1.2E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 SUPERFAMILY SSF52540 75 367 3.98E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 26 363 8.3E-69 T 16-09-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Gene3D G3DSA:3.40.50.300 25 209 1.1E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Pfam PF16124 RecQ zinc-binding 449 490 9.2E-6 T 16-09-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 PANTHER PTHR13710 1 367 1.2E-117 T 16-09-2016 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 PANTHER PTHR13710 446 489 1.2E-117 T 16-09-2016 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Pfam PF00270 DEAD/DEAH box helicase 32 199 9.4E-16 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Gene3D G3DSA:3.40.50.300 222 369 1.5E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Pfam PF00271 Helicase conserved C-terminal domain 253 347 7.1E-13 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 SMART SM00490 267 348 7.1E-22 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 Gene3D G3DSA:3.40.50.2020 574 718 3.7E-8 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 SMART SM00487 26 226 6.9E-24 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 SUPERFAMILY SSF53271 679 718 9.7E-7 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 PANTHER PTHR13710:SF81 1 367 1.2E-117 T 16-09-2016 Spa2297_RS24630 33719f806ca3fa915c67c14d0e31e6bd 721 PANTHER PTHR13710:SF81 446 489 1.2E-117 T 16-09-2016 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 SMART SM00347 31 132 1.3E-19 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 9.4E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 9.4E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 9.4E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 9.4E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 Pfam PF12802 MarR family 37 95 5.2E-13 T 16-09-2016 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PANTHER PTHR33164 17 148 1.4E-46 T 16-09-2016 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 SUPERFAMILY SSF46785 11 144 2.05E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 PANTHER PTHR33164:SF2 17 148 1.4E-46 T 16-09-2016 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 Gene3D G3DSA:1.10.287.100 102 147 4.8E-14 T 16-09-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 Spa2297_RS31245 aeb0a443ee397df47e1a1cece2d5ab5e 148 Gene3D G3DSA:1.10.10.10 37 101 1.1E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 Gene3D G3DSA:1.10.10.60 2 45 9.1E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 5.2E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 5.2E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 48 7.4E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 PANTHER PTHR30055 2 222 2.6E-62 T 16-09-2016 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 PANTHER PTHR30055:SF10 2 222 2.6E-62 T 16-09-2016 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 Gene3D G3DSA:1.10.357.10 46 178 3.4E-36 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 48 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS30065 5274ad0e58fc9b7c85ab5d59cbcb3d0a 226 SUPERFAMILY SSF46689 2 74 1.56E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PRINTS PR00133 Glycosyl hydrolase family 3 signature 280 298 3.7E-22 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PRINTS PR00133 Glycosyl hydrolase family 3 signature 110 126 3.7E-22 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PRINTS PR00133 Glycosyl hydrolase family 3 signature 210 226 3.7E-22 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PRINTS PR00133 Glycosyl hydrolase family 3 signature 133 152 3.7E-22 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PRINTS PR00133 Glycosyl hydrolase family 3 signature 179 195 3.7E-22 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 SUPERFAMILY SSF51445 6 46 3.58E-86 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 SUPERFAMILY SSF51445 74 370 3.58E-86 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620:SF37 3 42 0.0 T 16-09-2016 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620:SF37 82 490 0.0 T 16-09-2016 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620:SF37 514 759 0.0 T 16-09-2016 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 Pfam PF14310 Fibronectin type III-like domain 676 744 1.6E-13 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620 3 42 0.0 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 SUPERFAMILY SSF52279 393 640 1.57E-46 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 392 638 1.8E-51 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 Gene3D G3DSA:3.40.50.1700 385 640 9.8E-66 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620 514 759 0.0 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 SMART SM01217 676 746 2.3E-17 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 Gene3D G3DSA:3.20.20.300 6 369 5.1E-94 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 28 356 3.2E-60 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS31195 e5941077f5cf684c20c3d8ea8631d921 764 PANTHER PTHR30620 82 490 0.0 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 5.0E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 SMART SM00345 25 84 1.5E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 Pfam PF07729 FCD domain 114 235 3.2E-19 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.7E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.7E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 Gene3D G3DSA:1.20.120.530 111 242 9.9E-21 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 Gene3D G3DSA:1.10.10.10 16 93 1.7E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PANTHER PTHR11751 111 130 1.1E-28 T 16-09-2016 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PANTHER PTHR11751 24 91 1.1E-28 T 16-09-2016 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PANTHER PTHR11751:SF314 111 130 1.1E-28 T 16-09-2016 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 PANTHER PTHR11751:SF314 24 91 1.1E-28 T 16-09-2016 Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 SMART SM00895 113 236 1.5E-15 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 SUPERFAMILY SSF46785 17 101 6.62E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32070 7e3cd3908830a38a385038cb9e439ded 249 SUPERFAMILY SSF48008 112 241 7.32E-21 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS22510 c6933f14b96e3513db11bddc963dec90 505 PANTHER PTHR34704 8 379 8.8E-31 T 16-09-2016 Spa2297_RS22510 c6933f14b96e3513db11bddc963dec90 505 SUPERFAMILY SSF52540 8 195 1.38E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22510 c6933f14b96e3513db11bddc963dec90 505 Gene3D G3DSA:3.40.50.300 7 183 1.4E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 349 5.3E-81 T 16-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 Gene3D G3DSA:3.20.20.140 11 350 7.0E-103 T 16-09-2016 Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 SUPERFAMILY SSF51556 11 347 9.48E-77 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 Hamap MF_00540 Adenosine deaminase [add]. 9 351 55.551 T 16-09-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 PANTHER PTHR11409 5 350 8.8E-102 T 16-09-2016 Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 PANTHER PTHR11409:SF43 5 350 8.8E-102 T 16-09-2016 Spa2297_RS02345 d1bf25e9e866e8260b13ab3d9f970019 359 Pfam PF00962 Adenosine/AMP deaminase 14 348 3.6E-77 T 16-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 Gene3D G3DSA:1.10.357.10 71 210 2.3E-17 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 71 4.4E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 Gene3D G3DSA:1.10.10.60 17 70 5.7E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 PANTHER PTHR30055:SF80 15 181 4.2E-25 T 16-09-2016 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 4.2E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 4.2E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 SUPERFAMILY SSF46689 17 88 7.18E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS21450 027e3522840a478e3cc96b6f26907ccb 229 PANTHER PTHR30055 15 181 4.2E-25 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 Gene3D G3DSA:3.40.50.880 2 187 3.2E-59 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PANTHER PTHR11922:SF7 2 185 7.3E-71 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00097 Anthranilate synthase component II signature 48 57 1.2E-29 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 5.0E-9 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 5.0E-9 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PANTHER PTHR11922 2 185 7.3E-71 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 Pfam PF00117 Glutamine amidotransferase class-I 4 186 1.0E-47 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 7.3E-58 T 16-09-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 SUPERFAMILY SSF52317 2 186 1.3E-51 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.8E-13 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.8E-13 T 16-09-2016 Spa2297_RS23985 464244fccadb26b35d14d53908e0aa06 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.8E-13 T 16-09-2016 Spa2297_RS31175 aa8488c3f3ca804cf8869dfba8a189af 361 PANTHER PTHR36512:SF1 18 355 7.7E-72 T 16-09-2016 Spa2297_RS31175 aa8488c3f3ca804cf8869dfba8a189af 361 Gene3D G3DSA:3.60.70.12 17 348 3.1E-108 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS31175 aa8488c3f3ca804cf8869dfba8a189af 361 Pfam PF03576 Peptidase family S58 35 338 3.4E-103 T 16-09-2016 IPR005321 Peptidase S58, DmpA Spa2297_RS31175 aa8488c3f3ca804cf8869dfba8a189af 361 PANTHER PTHR36512 18 355 7.7E-72 T 16-09-2016 Spa2297_RS31175 aa8488c3f3ca804cf8869dfba8a189af 361 SUPERFAMILY SSF56266 16 337 1.28E-84 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 SMART SM00836 242 356 3.3E-12 T 16-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 Pfam PF05746 DALR anticodon binding domain 242 356 3.3E-15 T 16-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 SMART SM01016 4 92 5.7E-18 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 Gene3D G3DSA:1.10.730.10 237 356 8.6E-21 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 SUPERFAMILY SSF47323 236 355 1.7E-16 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 PANTHER PTHR11956 232 356 4.0E-22 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 32 92 6.0E-12 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 SUPERFAMILY SSF55190 8 105 3.53E-15 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS22590 4a6eee234258409c327747d585479aa9 356 Gene3D G3DSA:3.30.1360.70 3 111 8.3E-21 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 Pfam PF12802 MarR family 20 66 5.4E-7 T 16-09-2016 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 Gene3D G3DSA:3.30.420.40 83 224 4.8E-36 T 16-09-2016 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 Pfam PF00480 ROK family 89 380 1.3E-27 T 16-09-2016 IPR000600 ROK family Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 Gene3D G3DSA:1.10.10.10 14 82 2.2E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 Gene3D G3DSA:3.30.420.40 225 371 3.4E-34 T 16-09-2016 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 SUPERFAMILY SSF46785 15 80 1.33E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 SUPERFAMILY SSF53067 86 393 9.86E-43 T 16-09-2016 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 PANTHER PTHR18964:SF108 63 397 7.8E-89 T 16-09-2016 Spa2297_RS11250 c6c754f79761796a11be53e810186313 403 PANTHER PTHR18964 63 397 7.8E-89 T 16-09-2016 Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 PANTHER PTHR21021:SF19 273 577 2.4E-64 T 16-09-2016 Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 SUPERFAMILY SSF55874 607 693 3.01E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 PANTHER PTHR21021 273 577 2.4E-64 T 16-09-2016 Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 Gene3D G3DSA:3.30.450.40 141 327 1.1E-24 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 SUPERFAMILY SSF81606 365 569 2.88E-9 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 377 569 3.7E-54 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 SUPERFAMILY SSF55781 234 337 1.37E-5 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 Pfam PF13581 Histidine kinase-like ATPase domain 590 676 6.9E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21340 a7330227e2d871f387ecd958bfd447f2 695 SMART SM00331 351 568 6.2E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS20655 599c08a048e39c6fbf4f2f0d28ce075c 312 PANTHER PTHR23416 8 302 7.6E-127 T 16-09-2016 Spa2297_RS20655 599c08a048e39c6fbf4f2f0d28ce075c 312 SUPERFAMILY SSF51569 11 290 6.23E-85 T 16-09-2016 Spa2297_RS20655 599c08a048e39c6fbf4f2f0d28ce075c 312 Gene3D G3DSA:3.20.20.70 11 277 1.3E-99 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS20655 599c08a048e39c6fbf4f2f0d28ce075c 312 PANTHER PTHR23416:SF1 8 302 7.6E-127 T 16-09-2016 Spa2297_RS20655 599c08a048e39c6fbf4f2f0d28ce075c 312 Pfam PF03102 NeuB family 41 277 1.7E-81 T 16-09-2016 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Spa2297_RS06275 ae1a137752cd176e0ad054d4721b3d2e 193 SUPERFAMILY SSF55729 20 190 1.64E-38 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06275 ae1a137752cd176e0ad054d4721b3d2e 193 PANTHER PTHR13256:SF21 2 193 6.1E-60 T 16-09-2016 Spa2297_RS06275 ae1a137752cd176e0ad054d4721b3d2e 193 Gene3D G3DSA:3.40.630.30 17 190 5.7E-44 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06275 ae1a137752cd176e0ad054d4721b3d2e 193 PANTHER PTHR13256 2 193 6.1E-60 T 16-09-2016 Spa2297_RS06275 ae1a137752cd176e0ad054d4721b3d2e 193 Pfam PF13302 Acetyltransferase (GNAT) domain 28 165 2.6E-26 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PRINTS PR00625 DnaJ domain signature 60 79 2.6E-23 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PRINTS PR00625 DnaJ domain signature 6 24 2.6E-23 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PRINTS PR00625 DnaJ domain signature 24 39 2.6E-23 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PRINTS PR00625 DnaJ domain signature 40 60 2.6E-23 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 SMART SM00271 3 60 4.0E-30 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Pfam PF00226 DnaJ domain 4 65 7.0E-27 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PANTHER PTHR24078:SF190 100 308 4.6E-78 T 16-09-2016 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Pfam PF01556 DnaJ C terminal domain 143 291 1.4E-34 T 16-09-2016 IPR002939 Chaperone DnaJ, C-terminal Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Gene3D G3DSA:2.60.260.20 139 212 6.3E-15 T 16-09-2016 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 SUPERFAMILY SSF49493 217 302 6.54E-22 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 SUPERFAMILY SSF46565 3 91 1.7E-31 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PANTHER PTHR24078:SF190 1 70 4.6E-78 T 16-09-2016 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 SUPERFAMILY SSF49493 138 225 6.67E-17 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Gene3D G3DSA:1.10.287.110 2 73 1.1E-32 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Gene3D G3DSA:1.10.287.110 110 131 1.1E-32 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PANTHER PTHR24078 1 70 4.6E-78 T 16-09-2016 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 PANTHER PTHR24078 100 308 4.6E-78 T 16-09-2016 Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 16-09-2016 IPR018253 DnaJ domain, conserved site Spa2297_RS14030 83704c3c52c283c6967676f49eafb313 317 Gene3D G3DSA:2.60.260.20 214 291 5.1E-21 T 16-09-2016 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 Pfam PF13377 Periplasmic binding protein-like domain 168 344 1.1E-33 T 16-09-2016 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 Gene3D G3DSA:3.40.50.2300 172 312 4.2E-49 T 16-09-2016 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 PANTHER PTHR30146 2 346 6.8E-111 T 16-09-2016 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 8.9E-14 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 Gene3D G3DSA:1.10.260.40 5 55 6.5E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 SUPERFAMILY SSF47413 3 61 1.69E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 SUPERFAMILY SSF53822 60 316 3.14E-58 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 SMART SM00354 3 73 5.4E-21 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 Gene3D G3DSA:3.40.50.2300 56 171 2.1E-31 T 16-09-2016 Spa2297_RS01235 d55ade83bf76a88320acf6e5a7adf6ff 351 PANTHER PTHR30146:SF30 2 346 6.8E-111 T 16-09-2016 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 PANTHER PTHR22881 13 154 2.9E-43 T 16-09-2016 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 SUPERFAMILY SSF55486 3 149 3.91E-36 T 16-09-2016 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 3.2E-30 T 16-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 16-09-2016 IPR020549 Endoribonuclease YbeY, conserved site Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 Pfam PF02130 Uncharacterized protein family UPF0054 16 147 5.6E-35 T 16-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 Gene3D G3DSA:3.40.390.30 5 156 1.4E-41 T 16-09-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 Spa2297_RS10670 9318f1cc1cc680589bf9433139806e72 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.049 T 16-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF50156 794 874 1.08E-14 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 PANTHER PTHR32060 92 1117 0.0 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Pfam PF14685 Tricorn protease PDZ domain 794 881 1.0E-24 T 16-09-2016 IPR029414 Tricorn protease, PDZ domain Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 PIRSF PIRSF036421 1 1100 0.0 T 16-09-2016 IPR012393 Tricorn protease GO:0008236 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SMART SM00245 875 1067 8.7E-14 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:3.90.226.10 891 1097 1.4E-36 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:2.30.42.10 792 888 5.2E-31 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF69304 8 261 5.36E-27 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:2.130.10.10 446 700 1.3E-85 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:2.130.10.10 366 413 1.3E-85 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Pfam PF03572 Peptidase family S41 912 1065 4.7E-22 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:2.120.10.60 5 273 1.7E-56 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF69304 342 407 1.57E-17 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF69304 579 687 1.57E-17 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF69304 439 534 1.57E-17 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Gene3D G3DSA:3.30.750.44 709 778 2.3E-30 T 16-09-2016 Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Pfam PF14684 Tricorn protease C1 domain 712 779 3.9E-27 T 16-09-2016 IPR028204 Tricorn protease C1 domain Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF52096 884 1093 1.82E-62 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 SUPERFAMILY SSF52096 709 788 1.82E-62 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Pfam PF07676 WD40-like Beta Propeller Repeat 47 64 0.004 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 Pfam PF07676 WD40-like Beta Propeller Repeat 500 532 0.0069 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS13785 38730a48c7a9fbaac07dbba50dbca1a7 1118 PANTHER PTHR32060:SF12 92 1117 0.0 T 16-09-2016 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 Gene3D G3DSA:1.10.260.40 8 81 1.1E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 PANTHER PTHR10245 10 184 2.3E-33 T 16-09-2016 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 SUPERFAMILY SSF51182 65 173 1.34E-22 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 SMART SM00530 13 68 1.0E-16 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 Gene3D G3DSA:2.60.120.10 87 177 5.5E-16 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 Pfam PF07883 Cupin domain 106 174 3.3E-16 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 SUPERFAMILY SSF47413 5 74 2.76E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 Pfam PF01381 Helix-turn-helix 14 68 3.2E-14 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS04330 e23d58ab1466e8fcfae4b5f4e7398747 191 PANTHER PTHR10245:SF20 10 184 2.3E-33 T 16-09-2016 Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 Gene3D G3DSA:3.40.50.2300 492 647 1.6E-58 T 16-09-2016 Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 PANTHER PTHR32196 20 340 8.0E-151 T 16-09-2016 Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 Gene3D G3DSA:3.40.50.2300 374 491 2.4E-40 T 16-09-2016 Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 Pfam PF13407 Periplasmic binding protein domain 376 628 4.5E-65 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 SUPERFAMILY SSF53822 356 647 6.91E-90 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 PANTHER PTHR32196:SF34 20 340 8.0E-151 T 16-09-2016 Spa2297_RS11610 1edd994242395a2f0f576b75c2caf0cb 651 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 315 2.1E-46 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Gene3D G3DSA:3.40.50.620 19 205 3.0E-140 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Gene3D G3DSA:3.40.50.620 352 569 3.0E-140 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 SUPERFAMILY SSF50677 206 345 3.4E-54 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 807 871 3.7E-16 T 16-09-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Hamap MF_02004 Valine--tRNA ligase [valS]. 16 872 15.318 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Gene3D G3DSA:3.90.740.10 206 345 1.8E-46 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Gene3D G3DSA:1.10.730.10 572 746 5.6E-56 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PANTHER PTHR11946 7 865 0.0 T 16-09-2016 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 SUPERFAMILY SSF52374 14 206 2.95E-137 T 16-09-2016 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 SUPERFAMILY SSF52374 352 581 2.95E-137 T 16-09-2016 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 567 1.4E-192 T 16-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 SUPERFAMILY SSF46589 807 871 1.94E-13 T 16-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PANTHER PTHR11946:SF5 7 865 0.0 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Pfam PF08264 Anticodon-binding domain of tRNA 613 754 2.0E-37 T 16-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 TIGRFAM TIGR00422 valS: valine--tRNA ligase 17 849 0.0 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 Gene3D G3DSA:1.10.287.380 801 871 1.7E-7 T 16-09-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 SUPERFAMILY SSF47323 583 820 6.35E-51 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PRINTS PR00986 Valyl-tRNA synthetase signature 357 370 4.9E-39 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PRINTS PR00986 Valyl-tRNA synthetase signature 451 472 4.9E-39 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PRINTS PR00986 Valyl-tRNA synthetase signature 50 61 4.9E-39 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PRINTS PR00986 Valyl-tRNA synthetase signature 482 500 4.9E-39 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS11055 6e897848be19cc604c95a56fd33872fa 874 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 4.9E-39 T 16-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 45 90 5.8E-12 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 273 332 1.2E-7 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 PANTHER PTHR32439:SF3 29 401 2.8E-51 T 16-09-2016 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 Gene3D G3DSA:3.30.413.10 347 416 9.6E-5 T 16-09-2016 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 SUPERFAMILY SSF55124 26 106 1.29E-19 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 SUPERFAMILY SSF56014 346 425 1.44E-6 T 16-09-2016 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 SUPERFAMILY SSF55124 252 337 1.39E-12 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 PANTHER PTHR32439 29 401 2.8E-51 T 16-09-2016 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 28 405 3.0E-73 T 16-09-2016 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 Gene3D G3DSA:3.90.480.10 258 338 2.3E-22 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS00580 a31e89c39383fc07ae6928255a6f40a7 439 Gene3D G3DSA:3.90.480.10 40 109 2.3E-22 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SMART SM00382 601 794 8.4E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SMART SM00382 199 346 3.9E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 5.2E-42 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 5.2E-42 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 5.2E-42 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 5.2E-42 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SUPERFAMILY SSF52540 160 549 7.99E-92 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 3.0E-11 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SUPERFAMILY SSF52540 550 852 4.82E-79 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Gene3D G3DSA:1.10.1780.10 4 149 4.7E-33 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SUPERFAMILY SSF81923 4 157 2.06E-29 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PANTHER PTHR11638 1 857 0.0 T 16-09-2016 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 SMART SM01086 768 857 7.6E-38 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Gene3D G3DSA:3.40.50.300 160 343 2.9E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 19 69 1.3E-4 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 1.0E-12 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 855 0.0 T 16-09-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Gene3D G3DSA:3.40.50.300 556 779 2.4E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 1.3E-27 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 16-09-2016 IPR028299 ClpA/B, conserved site 2 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Gene3D G3DSA:1.10.8.60 780 858 1.3E-30 T 16-09-2016 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 PANTHER PTHR11638:SF120 1 857 0.0 T 16-09-2016 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 16-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Gene3D G3DSA:1.10.8.60 345 428 1.0E-34 T 16-09-2016 Spa2297_RS17530 d692f530b8719998c22e33b912085b9e 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 761 4.7E-53 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 PANTHER PTHR12133 2 279 4.1E-99 T 16-09-2016 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 Gene3D G3DSA:3.10.330.20 2 75 8.4E-33 T 16-09-2016 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 PIRSF PIRSF017269 7 277 1.8E-85 T 16-09-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 2.9E-28 T 16-09-2016 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 PANTHER PTHR12133:SF1 2 279 4.1E-99 T 16-09-2016 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 244 3.0E-23 T 16-09-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 Gene3D G3DSA:3.40.50.150 77 283 3.0E-66 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS06405 3c921d965579978dc02505b2498024fd 300 SUPERFAMILY SSF53335 13 266 4.55E-72 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 PANTHER PTHR33406:SF5 1 743 1.3E-268 T 16-09-2016 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 SUPERFAMILY SSF82866 475 711 1.83E-27 T 16-09-2016 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 Pfam PF03176 MMPL family 45 382 1.1E-88 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 Pfam PF03176 MMPL family 465 711 7.9E-35 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 SUPERFAMILY SSF82866 136 334 4.58E-34 T 16-09-2016 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 PANTHER PTHR33406 1 743 1.3E-268 T 16-09-2016 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 Gene3D G3DSA:1.20.1640.10 135 336 2.7E-35 T 16-09-2016 Spa2297_RS13775 2ebd88a86661e1e04622787d38fa3454 749 Gene3D G3DSA:1.20.1640.10 491 717 3.5E-32 T 16-09-2016 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 68 171 6.4E-19 T 16-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 PIRSF PIRSF500136 1 402 2.0E-117 T 16-09-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 SUPERFAMILY SSF51735 6 183 4.12E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 302 393 1.0E-13 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 SUPERFAMILY SSF52413 288 395 3.66E-19 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 PANTHER PTHR11374:SF4 3 394 8.9E-118 T 16-09-2016 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 PANTHER PTHR11374 3 394 8.9E-118 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 189 256 2.4E-18 T 16-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 54 391 4.8E-87 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 Gene3D G3DSA:3.40.50.720 2 184 1.5E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 PIRSF PIRSF000124 47 401 3.2E-38 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 Gene3D G3DSA:3.40.50.720 220 394 3.8E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 SUPERFAMILY SSF48179 189 280 2.04E-20 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS20130 4a0d61a1f65b09b5f84b8ffad16d1bb2 402 SMART SM00984 301 396 1.1E-16 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376:SF32 213 628 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376:SF32 2 157 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376:SF32 659 1146 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376 213 628 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376 2 157 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376 659 1146 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 16-09-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.6E-28 T 16-09-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376:SF32 1187 1278 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 PANTHER PTHR19376 1187 1278 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1251 0.0 T 16-09-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 SUPERFAMILY SSF64484 5 1251 0.0 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF04998 RNA polymerase Rpb1, domain 5 838 1199 3.3E-65 T 16-09-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 9.5E-82 T 16-09-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Gene3D G3DSA:2.40.40.20 492 564 3.7E-38 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Gene3D G3DSA:2.40.40.20 424 451 3.7E-38 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 824 4.7E-13 T 16-09-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 731 2.0E-23 T 16-09-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1260 10.016 T 16-09-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 Gene3D G3DSA:2.40.50.100 1041 1095 1.4E-8 T 16-09-2016 Spa2297_RS19650 3eda3c1c4e049797af9e0d263f1028a3 1299 SMART SM00663 310 589 6.6E-174 T 16-09-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 Pfam PF00293 NUDIX domain 47 169 6.0E-24 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 24 179 1.9E-35 T 16-09-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 PANTHER PTHR10885 24 181 2.4E-54 T 16-09-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 SUPERFAMILY SSF55811 23 182 4.59E-42 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 PIRSF PIRSF018427 2 192 6.9E-53 T 16-09-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 20 191 31.204 T 16-09-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 Spa2297_RS28110 f7330ea2fae66b67a7874d4829bb3d58 197 Gene3D G3DSA:3.90.79.10 22 183 7.3E-47 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 SUPERFAMILY SSF52821 352 453 3.67E-22 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 SMART SM00849 13 182 1.6E-16 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 Pfam PF00581 Rhodanese-like domain 366 443 1.8E-6 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 SUPERFAMILY SSF52821 221 348 9.95E-16 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 PANTHER PTHR11935 1 287 4.8E-132 T 16-09-2016 Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 PANTHER PTHR11935:SF114 1 287 4.8E-132 T 16-09-2016 Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 SMART SM00450 357 450 1.1E-13 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 Gene3D G3DSA:3.40.250.10 352 452 1.7E-17 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 Gene3D G3DSA:3.60.15.10 12 238 2.4E-44 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 Gene3D G3DSA:3.40.250.10 255 348 9.1E-7 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 SUPERFAMILY SSF56281 11 242 4.34E-37 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS03885 e186503b605d39a62118904ab71c218b 454 Pfam PF00753 Metallo-beta-lactamase superfamily 28 182 1.2E-7 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 SUPERFAMILY SSF52091 9 112 1.14E-23 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 Gene3D G3DSA:3.30.750.24 9 113 7.4E-29 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 Pfam PF01740 STAS domain 12 111 1.9E-12 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 PANTHER PTHR33495 1 119 2.1E-33 T 16-09-2016 Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 10 110 6.5E-22 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS00215 7e5c4910c565573ae0f1480542893940 129 PANTHER PTHR33495:SF3 1 119 2.1E-33 T 16-09-2016 Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 19 32 - T 16-09-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 SUPERFAMILY SSF81330 18 125 3.66E-24 T 16-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 PANTHER PTHR30266 2 155 7.4E-40 T 16-09-2016 Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 10 145 3.4E-34 T 16-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 9 146 1.1E-21 T 16-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 Spa2297_RS13890 f615fa2e1e0b731db8587d37866f3d14 156 PANTHER PTHR30266:SF2 2 155 7.4E-40 T 16-09-2016 Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 Gene3D G3DSA:3.40.30.10 98 185 2.2E-10 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 SUPERFAMILY SSF52833 31 187 1.12E-48 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 135 153 - T 16-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 35 177 1.6E-49 T 16-09-2016 Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 PANTHER PTHR10371 36 190 3.0E-67 T 16-09-2016 Spa2297_RS19215 0bbd2eb0d217a03f39c6c3876cd7cfa4 290 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 35 177 2.7E-43 T 16-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 Gene3D G3DSA:1.10.1740.10 17 94 1.3E-18 T 16-09-2016 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 Pfam PF04545 Sigma-70, region 4 126 174 5.7E-13 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 SUPERFAMILY SSF88659 112 176 7.2E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 PANTHER PTHR30173:SF17 17 184 3.6E-65 T 16-09-2016 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 SUPERFAMILY SSF88946 19 104 1.14E-16 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 Gene3D G3DSA:1.10.10.10 116 178 4.3E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 PANTHER PTHR30173 17 184 3.6E-65 T 16-09-2016 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 175 9.6E-23 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28945 9303727653026b95dfd5c99913050e2d 184 Pfam PF04542 Sigma-70 region 2 25 92 1.3E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 Gene3D G3DSA:3.30.565.10 554 694 3.0E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 Pfam PF00672 HAMP domain 384 469 1.4E-12 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 Pfam PF08376 Nitrate and nitrite sensing 101 364 3.1E-44 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423:SF468 898 947 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423 397 435 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423 898 947 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423:SF468 397 435 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423:SF468 802 878 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423 802 878 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 588 695 4.5E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423:SF468 1 11 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423 1 11 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 SMART SM00304 403 473 0.001 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 SMART SM00387 585 697 6.2E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423 453 700 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 PANTHER PTHR24423:SF468 453 700 6.1E-104 T 16-09-2016 Spa2297_RS23470 a8b32fbb7460cc16ab39be537f65e95f 1092 SUPERFAMILY SSF55874 577 694 6.68E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 Gene3D G3DSA:3.90.79.10 175 318 3.4E-26 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 ProSitePatterns PS00893 Nudix box signature. 212 233 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 Pfam PF00583 Acetyltransferase (GNAT) family 69 149 3.2E-8 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 Pfam PF00293 NUDIX domain 178 308 1.7E-17 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 PANTHER PTHR22769 176 306 1.7E-23 T 16-09-2016 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 SUPERFAMILY SSF55729 22 169 2.52E-22 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 Gene3D G3DSA:3.40.630.30 22 171 9.5E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 PANTHER PTHR22769:SF14 176 306 1.7E-23 T 16-09-2016 Spa2297_RS14915 ab2e0f2daae28f59e02a00389caf1cf8 320 SUPERFAMILY SSF55811 173 317 2.3E-24 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 SUPERFAMILY SSF52540 17 233 6.29E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 PANTHER PTHR24220 16 254 4.1E-172 T 16-09-2016 Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 SMART SM00382 43 229 1.5E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 Gene3D G3DSA:3.40.50.300 18 233 1.9E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 PANTHER PTHR24220:SF484 16 254 4.1E-172 T 16-09-2016 Spa2297_RS13410 49fbb50cbd4c6c5d5f7896191aea4d23 256 Pfam PF00005 ABC transporter 34 180 3.4E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 SUPERFAMILY SSF53955 45 123 8.44E-33 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Gene3D G3DSA:3.10.350.10 179 228 2.2E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Gene3D G3DSA:2.70.70.10 284 427 6.0E-42 T 16-09-2016 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 SUPERFAMILY SSF51261 274 426 4.29E-46 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 SUPERFAMILY SSF54106 179 228 7.85E-6 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Pfam PF06737 Transglycosylase-like domain 42 117 1.9E-36 T 16-09-2016 IPR010618 Transglycosylase-like Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 PANTHER PTHR21666:SF200 245 432 2.2E-41 T 16-09-2016 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Pfam PF01551 Peptidase family M23 325 416 2.3E-31 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 PANTHER PTHR21666 245 432 2.2E-41 T 16-09-2016 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Gene3D G3DSA:1.10.530.10 22 123 4.7E-43 T 16-09-2016 Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 SMART SM00257 180 229 6.4E-6 T 16-09-2016 IPR018392 LysM domain Spa2297_RS28830 db9c65e99720bd8ef126600138ce3501 433 Pfam PF01476 LysM domain 181 226 3.5E-7 T 16-09-2016 IPR018392 LysM domain Spa2297_RS05180 c80b340159e46ef7b144acdcd107e5d6 144 PANTHER PTHR36222 6 144 1.3E-52 T 16-09-2016 Spa2297_RS05180 c80b340159e46ef7b144acdcd107e5d6 144 SUPERFAMILY SSF103196 11 137 5.58E-35 T 16-09-2016 Spa2297_RS05180 c80b340159e46ef7b144acdcd107e5d6 144 SMART SM00960 18 108 2.5E-27 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS05180 c80b340159e46ef7b144acdcd107e5d6 144 Gene3D G3DSA:3.30.450.30 13 134 1.9E-25 T 16-09-2016 Spa2297_RS05180 c80b340159e46ef7b144acdcd107e5d6 144 Pfam PF03259 Roadblock/LC7 domain 17 107 8.1E-25 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SUPERFAMILY SSF81606 420 612 8.89E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SMART SM00331 384 611 3.2E-17 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 Pfam PF13185 GAF domain 243 355 1.4E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 PANTHER PTHR21021 127 175 9.3E-35 T 16-09-2016 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SUPERFAMILY SSF55781 31 170 3.27E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 PANTHER PTHR21021:SF19 127 175 9.3E-35 T 16-09-2016 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 PANTHER PTHR21021:SF19 360 613 9.3E-35 T 16-09-2016 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 Gene3D G3DSA:3.30.450.40 31 172 2.5E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 Gene3D G3DSA:3.30.450.40 190 358 5.7E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 420 612 1.6E-33 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 PANTHER PTHR21021 360 613 9.3E-35 T 16-09-2016 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 Pfam PF01590 GAF domain 33 162 1.8E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SMART SM00065 214 364 0.27 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SMART SM00065 26 172 2.0E-15 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS31860 97c250535d2658c506c6544d448326a6 613 SUPERFAMILY SSF55781 217 361 1.64E-9 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS09495 58686ba627d2e9ecb8e377856eeee448 363 PANTHER PTHR30472 5 360 1.1E-174 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS09495 58686ba627d2e9ecb8e377856eeee448 363 SUPERFAMILY SSF81345 20 354 2.48E-86 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS09495 58686ba627d2e9ecb8e377856eeee448 363 Pfam PF01032 FecCD transport family 37 354 5.2E-97 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS09495 58686ba627d2e9ecb8e377856eeee448 363 Gene3D G3DSA:1.10.3470.10 23 358 3.5E-113 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS09495 58686ba627d2e9ecb8e377856eeee448 363 PANTHER PTHR30472:SF3 5 360 1.1E-174 T 16-09-2016 Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 Pfam PF02779 Transketolase, pyrimidine binding domain 9 182 4.0E-46 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 SMART SM00861 9 184 5.7E-66 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 PANTHER PTHR11624 1 327 1.9E-198 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 SUPERFAMILY SSF52922 197 326 4.45E-37 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 PANTHER PTHR11624:SF79 1 327 1.9E-198 T 16-09-2016 Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 SUPERFAMILY SSF52518 8 194 1.84E-67 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 Pfam PF02780 Transketolase, C-terminal domain 200 321 1.6E-36 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 Gene3D G3DSA:3.40.50.920 204 325 1.4E-40 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS16815 7449d8c84d179663144a288cba673799 334 Gene3D G3DSA:3.40.50.970 7 196 6.4E-74 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS29280 bc11bac7d339fbb8f11b89f85d4c015b 190 SUPERFAMILY SSF54909 11 108 1.1E-19 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS29280 bc11bac7d339fbb8f11b89f85d4c015b 190 Pfam PF03992 Antibiotic biosynthesis monooxygenase 11 86 8.2E-10 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS29280 bc11bac7d339fbb8f11b89f85d4c015b 190 Gene3D G3DSA:3.30.70.900 12 96 4.4E-16 T 16-09-2016 Spa2297_RS29280 bc11bac7d339fbb8f11b89f85d4c015b 190 PANTHER PTHR40057:SF1 1 184 9.1E-38 T 16-09-2016 Spa2297_RS29280 bc11bac7d339fbb8f11b89f85d4c015b 190 PANTHER PTHR40057 1 184 9.1E-38 T 16-09-2016 Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 12 170 2.1E-58 T 16-09-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 SUPERFAMILY SSF53271 13 170 5.9E-46 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 Gene3D G3DSA:3.40.50.2020 8 181 1.1E-60 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 182 35.666 T 16-09-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 Pfam PF00156 Phosphoribosyl transferase domain 34 157 4.5E-15 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS05730 4990c5401fe63702d4ae9b0991bfcfdb 182 PANTHER PTHR32315 7 169 2.2E-67 T 16-09-2016 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 PANTHER PTHR30154 1 140 4.6E-79 T 16-09-2016 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 PANTHER PTHR30154:SF16 1 140 4.6E-79 T 16-09-2016 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 Gene3D G3DSA:3.30.70.920 59 133 3.6E-18 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 SUPERFAMILY SSF46785 7 65 1.13E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 9.3E-12 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 9.3E-12 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 9.3E-12 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 1.6E-15 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 Gene3D G3DSA:1.10.10.10 7 58 3.2E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 SUPERFAMILY SSF54909 67 141 5.09E-16 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 Pfam PF01037 Lrp/AsnC ligand binding domain 79 138 2.2E-14 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04760 43cefef78a771c85c1d7e08708a18d0b 148 SMART SM00344 7 112 5.5E-32 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS01270 f8d53d278041c9dba5cdeab057cbcd66 604 Gene3D G3DSA:2.80.10.50 453 560 8.4E-7 T 16-09-2016 Spa2297_RS01270 f8d53d278041c9dba5cdeab057cbcd66 604 SUPERFAMILY SSF50370 443 580 5.4E-13 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS07720 c54dff935fb4ce05c29a379a6379cbb7 106 SUPERFAMILY SSF103481 6 104 1.11E-17 T 16-09-2016 Spa2297_RS07720 c54dff935fb4ce05c29a379a6379cbb7 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.2E-26 T 16-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 Spa2297_RS07720 c54dff935fb4ce05c29a379a6379cbb7 106 PANTHER PTHR30561:SF1 1 102 8.5E-44 T 16-09-2016 Spa2297_RS07720 c54dff935fb4ce05c29a379a6379cbb7 106 PANTHER PTHR30561 1 102 8.5E-44 T 16-09-2016 Spa2297_RS10180 6cf88167a1f54a9dc45200975e7c2a5b 349 PANTHER PTHR33371:SF5 1 340 6.1E-137 T 16-09-2016 Spa2297_RS10180 6cf88167a1f54a9dc45200975e7c2a5b 349 Pfam PF02470 MlaD protein 31 106 5.5E-15 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS10180 6cf88167a1f54a9dc45200975e7c2a5b 349 PANTHER PTHR33371 1 340 6.1E-137 T 16-09-2016 Spa2297_RS10180 6cf88167a1f54a9dc45200975e7c2a5b 349 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 293 5.4E-62 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 16-09-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 Gene3D G3DSA:3.20.20.70 1 365 7.8E-130 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 PANTHER PTHR11938 1 365 4.8E-111 T 16-09-2016 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 SUPERFAMILY SSF51395 1 364 1.59E-102 T 16-09-2016 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 46.868 T 16-09-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 365 5.7E-127 T 16-09-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 PANTHER PTHR11938:SF105 1 365 4.8E-111 T 16-09-2016 Spa2297_RS05580 c8d05df33db7c442b3b33e2d6a0f6103 368 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 3.0E-92 T 16-09-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 PANTHER PTHR30627:SF3 5 483 9.1E-167 T 16-09-2016 Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 Pfam PF00905 Penicillin binding protein transpeptidase domain 155 480 2.4E-56 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 SUPERFAMILY SSF56601 138 484 7.68E-79 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 Gene3D G3DSA:3.90.1310.10 73 142 4.1E-4 T 16-09-2016 Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 Gene3D G3DSA:3.40.710.10 143 485 1.4E-85 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS22395 8203c0e5a5f7aea2451e68ff4ec3756a 500 PANTHER PTHR30627 5 483 9.1E-167 T 16-09-2016 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PANTHER PTHR23429:SF0 97 592 5.7E-243 T 16-09-2016 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 SUPERFAMILY SSF55347 283 590 5.23E-113 T 16-09-2016 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 110 293 1.0E-62 T 16-09-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 108 591 3.1E-200 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 283 289 - T 16-09-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 Gene3D G3DSA:3.40.50.720 106 292 8.4E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 325 342 7.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 273 301 7.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 249 262 7.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 343 359 7.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 432 458 7.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 PANTHER PTHR23429 97 592 5.7E-243 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 106 591 87.785 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 Gene3D G3DSA:3.30.360.10 293 590 1.8E-122 T 16-09-2016 Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 SUPERFAMILY SSF51735 95 296 1.59E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27700 fd8669c0117b5d25eb9fdfbd0b6402f1 592 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 295 590 8.2E-114 T 16-09-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 SUPERFAMILY SSF51735 3 183 2.56E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.279 T 16-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 PANTHER PTHR21371 2 329 3.5E-192 T 16-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 Gene3D G3DSA:1.10.1040.10 38 326 1.8E-110 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 2.9E-64 T 16-09-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 Gene3D G3DSA:3.50.50.60 10 37 8.2E-4 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 1.2E-75 T 16-09-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 SUPERFAMILY SSF48179 184 329 4.08E-68 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS23340 cc470f47cb84c0b37c0c8bceb8251690 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 7.2E-132 T 16-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 Gene3D G3DSA:3.40.50.720 170 299 2.6E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 PANTHER PTHR11695:SF509 13 334 8.2E-103 T 16-09-2016 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 PANTHER PTHR11695 13 334 8.2E-103 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 SUPERFAMILY SSF50129 4 174 1.48E-44 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 Gene3D G3DSA:3.90.180.10 4 169 2.9E-45 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 SUPERFAMILY SSF51735 141 302 1.24E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 1.5E-24 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 Pfam PF00107 Zinc-binding dehydrogenase 176 289 5.9E-10 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS10110 ca023fc922853ad7553e80ec988de9bc 334 SMART SM00829 11 332 9.1E-6 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 SUPERFAMILY SSF81624 2 144 1.7E-33 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 280 41.567 T 16-09-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 PANTHER PTHR22993 1 283 6.9E-121 T 16-09-2016 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 Gene3D G3DSA:1.10.8.50 141 280 2.5E-47 T 16-09-2016 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 121 1.5E-32 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 SUPERFAMILY SSF46946 139 228 5.0E-28 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 PANTHER PTHR22993:SF15 1 283 6.9E-121 T 16-09-2016 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 139 226 3.9E-23 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 Gene3D G3DSA:3.20.190.10 2 129 1.3E-36 T 16-09-2016 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 SMART SM01232 139 231 3.1E-43 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 SUPERFAMILY SSF57716 231 280 5.99E-16 T 16-09-2016 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 SMART SM00898 2 123 3.5E-44 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 279 1.6E-86 T 16-09-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Spa2297_RS23650 8f939eddd1b5f276539c5d1391deee97 286 ProSitePatterns PS01242 Zinc finger FPG-type signature. 255 279 - T 16-09-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:3.40.50.300 167 347 5.1E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:3.40.50.300 494 667 9.7E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:3.40.50.300 702 730 9.7E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SUPERFAMILY SSF52540 167 445 1.39E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SMART SM00382 204 348 5.9E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SMART SM00382 541 691 1.5E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF02151 UvrB/uvrC motif 421 453 5.8E-7 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 16-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PANTHER PTHR11638:SF18 1 830 0.0 T 16-09-2016 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SUPERFAMILY SSF52540 490 801 8.57E-79 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SMART SM01086 719 810 6.8E-37 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:1.10.1780.10 1 143 3.1E-54 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 6.9E-55 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 329 1.1E-12 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 2.4E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 2.4E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 2.4E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 2.4E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:1.10.8.60 731 816 4.1E-32 T 16-09-2016 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Gene3D G3DSA:1.10.8.60 350 432 1.6E-33 T 16-09-2016 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 798 9.4E-26 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 PANTHER PTHR11638 1 830 0.0 T 16-09-2016 Spa2297_RS18335 2892fc1cdc7a5f423439ba95661143b6 841 SUPERFAMILY SSF81923 3 144 3.34E-33 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 PANTHER PTHR24220 6 256 9.3E-127 T 16-09-2016 Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 SMART SM00382 29 229 1.3E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 PANTHER PTHR24220:SF585 6 256 9.3E-127 T 16-09-2016 Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 Gene3D G3DSA:3.40.50.300 4 251 5.4E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 4.7E-113 T 16-09-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 SUPERFAMILY SSF52540 5 246 7.57E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS15480 d9bcf7a9b39f89276658b98ab72c2886 258 Pfam PF00005 ABC transporter 21 176 9.9E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 SUPERFAMILY SSF51905 154 324 1.14E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 314 7.8E-63 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 Gene3D G3DSA:3.50.50.60 5 111 2.3E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 7.0E-25 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 7.0E-25 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.0E-25 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 7.0E-25 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.0E-25 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 Gene3D G3DSA:3.30.390.30 334 420 1.7E-29 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 3.2E-15 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 3.2E-15 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.2E-15 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 292 3.2E-15 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 SUPERFAMILY SSF51905 6 199 8.7E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 SUPERFAMILY SSF55424 328 420 1.92E-25 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 Pfam PF14759 Reductase C-terminal 334 419 5.1E-15 T 16-09-2016 IPR028202 Reductase, C-terminal Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PANTHER PTHR22912:SF180 3 420 2.8E-154 T 16-09-2016 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 Gene3D G3DSA:3.50.50.60 112 324 9.4E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10420 0c297dde93ee16882ebbced5834f93cb 421 PANTHER PTHR22912 3 420 2.8E-154 T 16-09-2016 Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 SUPERFAMILY SSF53448 173 446 2.93E-36 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 Gene3D G3DSA:3.90.550.10 181 413 1.9E-12 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 PANTHER PTHR10587 68 336 1.9E-184 T 16-09-2016 Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 PANTHER PTHR10587:SF71 68 336 1.9E-184 T 16-09-2016 Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 PANTHER PTHR10587:SF71 366 392 1.9E-184 T 16-09-2016 Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 Pfam PF13506 Glycosyl transferase family 21 231 400 9.0E-19 T 16-09-2016 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|UniPathway: UPA00222 Spa2297_RS12125 5de64f12a7e0010ddd77c28629a247d4 663 PANTHER PTHR10587 366 392 1.9E-184 T 16-09-2016 Spa2297_RS19125 02fd80a093017650351f6e7a50c2128e 141 Pfam PF13581 Histidine kinase-like ATPase domain 20 121 6.4E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19125 02fd80a093017650351f6e7a50c2128e 141 SUPERFAMILY SSF55874 45 135 3.01E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 SUPERFAMILY SSF47240 2 153 5.41E-46 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 16-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PANTHER PTHR30295:SF10 1 153 1.4E-66 T 16-09-2016 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PIRSF PIRSF005900 1 156 1.5E-43 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 Gene3D G3DSA:1.20.1260.10 4 154 1.3E-44 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PANTHER PTHR30295 1 153 1.4E-66 T 16-09-2016 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 3.1E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 3.1E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 3.1E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS24350 a101b09778d207784694d374b2b1ea25 156 Pfam PF00210 Ferritin-like domain 18 153 3.1E-20 T 16-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spa2297_RS07520 64220650734dae5ba101846055207fff 385 PANTHER PTHR22604:SF14 1 325 7.8E-46 T 16-09-2016 Spa2297_RS07520 64220650734dae5ba101846055207fff 385 PANTHER PTHR22604 1 325 7.8E-46 T 16-09-2016 Spa2297_RS07520 64220650734dae5ba101846055207fff 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 2.9E-12 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS07520 64220650734dae5ba101846055207fff 385 Gene3D G3DSA:3.40.50.720 2 139 1.0E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07520 64220650734dae5ba101846055207fff 385 SUPERFAMILY SSF55347 132 290 1.05E-13 T 16-09-2016 Spa2297_RS07520 64220650734dae5ba101846055207fff 385 SUPERFAMILY SSF51735 5 151 1.01E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07520 64220650734dae5ba101846055207fff 385 Gene3D G3DSA:3.30.360.10 140 324 2.3E-19 T 16-09-2016 Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 Gene3D G3DSA:3.40.30.10 138 221 3.1E-12 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 PIRSF PIRSF035042 1 311 3.3E-81 T 16-09-2016 IPR010350 Thioredoxin-like ferredoxin, bacteria Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 PANTHER PTHR31902 4 304 4.9E-146 T 16-09-2016 Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 PANTHER PTHR31902:SF6 4 304 4.9E-146 T 16-09-2016 Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 SUPERFAMILY SSF52833 134 224 2.8E-14 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS24710 11ac264e5a696ed0f0930467d59cf936 314 Pfam PF06999 Sucrase/ferredoxin-like 17 219 2.6E-21 T 16-09-2016 IPR009737 Thioredoxin-like ferredoxin Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 281 417 3.5E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 Gene3D G3DSA:1.10.3720.10 5 130 2.3E-71 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 Gene3D G3DSA:1.10.3720.10 283 417 2.3E-71 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 SUPERFAMILY SSF161098 47 137 7.27E-47 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 SUPERFAMILY SSF161098 280 415 7.27E-47 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243 291 427 1.9E-79 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243 186 191 1.9E-79 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243:SF13 4 125 1.9E-79 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243:SF13 291 427 1.9E-79 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243:SF13 186 191 1.9E-79 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 SUPERFAMILY SSF160964 3 57 4.58E-7 T 16-09-2016 Spa2297_RS12875 258d2687240ef5fe4e14543d4125f42a 427 PANTHER PTHR32243 4 125 1.9E-79 T 16-09-2016 Spa2297_RS17075 e75d9864f531c94c04f605c3d038dcbc 292 Pfam PF13354 Beta-lactamase enzyme family 29 260 1.1E-52 T 16-09-2016 Spa2297_RS17075 e75d9864f531c94c04f605c3d038dcbc 292 PANTHER PTHR35333:SF3 3 292 5.3E-108 T 16-09-2016 Spa2297_RS17075 e75d9864f531c94c04f605c3d038dcbc 292 PANTHER PTHR35333 3 292 5.3E-108 T 16-09-2016 Spa2297_RS17075 e75d9864f531c94c04f605c3d038dcbc 292 Gene3D G3DSA:3.40.710.10 9 289 1.6E-60 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS17075 e75d9864f531c94c04f605c3d038dcbc 292 SUPERFAMILY SSF56601 10 287 4.87E-45 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290 346 465 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290 3 279 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Gene3D G3DSA:3.90.76.10 117 187 3.5E-10 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 SUPERFAMILY SSF53850 55 287 2.48E-33 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Gene3D G3DSA:3.40.190.10 188 288 3.4E-15 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 359 460 1.5E-12 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 120 294 6.3E-23 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 542 632 2.1E-5 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290 560 743 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290:SF29 560 743 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 SUPERFAMILY SSF53850 559 731 3.1E-24 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 SUPERFAMILY SSF53850 358 462 1.5E-15 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290:SF29 346 465 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 PANTHER PTHR30290:SF29 3 279 4.2E-203 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Gene3D G3DSA:3.10.105.10 375 455 1.8E-66 T 16-09-2016 Spa2297_RS21550 8b4ced78ea6e7807807ef0b8b9d7c995 747 Gene3D G3DSA:3.10.105.10 560 704 1.8E-66 T 16-09-2016 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 Gene3D G3DSA:1.25.40.10 158 415 2.6E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 Gene3D G3DSA:1.25.40.10 29 157 3.8E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 SMART SM00028 143 176 30.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 SMART SM00028 103 136 1.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 SMART SM00028 183 216 110.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 SMART SM00028 67 100 110.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 Pfam PF12770 CHAT domain 608 896 1.0E-28 T 16-09-2016 IPR024983 CHAT domain Spa2297_RS28585 405f08c3482f4e8a2005105e7b5e0040 904 SUPERFAMILY SSF48452 58 224 1.32E-20 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 Gene3D G3DSA:3.30.70.1280 3 89 4.9E-28 T 16-09-2016 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 SUPERFAMILY SSF160379 3 180 6.93E-53 T 16-09-2016 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 PANTHER PTHR36439:SF1 2 182 4.0E-50 T 16-09-2016 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 PANTHER PTHR36439 2 182 4.0E-50 T 16-09-2016 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 PIRSF PIRSF008502 2 182 9.7E-50 T 16-09-2016 IPR012545 Protein of unknown function DUF1697 Spa2297_RS25735 dc2db30c3400c60ba077659c12e444ae 182 Pfam PF08002 Protein of unknown function (DUF1697) 3 138 7.7E-44 T 16-09-2016 IPR012545 Protein of unknown function DUF1697 Spa2297_RS10770 1bfc4c938733170d994a9dff68ffb33e 266 Pfam PF11296 Protein of unknown function (DUF3097) 4 266 9.3E-122 T 16-09-2016 IPR021447 Protein of unknown function DUF3097 Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 Pfam PF00483 Nucleotidyl transferase 4 236 4.0E-43 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 PANTHER PTHR22572 3 354 1.9E-107 T 16-09-2016 Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 Gene3D G3DSA:2.160.10.10 258 343 4.4E-14 T 16-09-2016 Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 SUPERFAMILY SSF53448 4 242 1.71E-66 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 SUPERFAMILY SSF53448 279 328 1.71E-66 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 PANTHER PTHR22572:SF15 3 354 1.9E-107 T 16-09-2016 Spa2297_RS13160 2b75c45789ba682abbc7385ee9cdb676 360 Gene3D G3DSA:3.90.550.10 2 238 2.1E-63 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 Gene3D G3DSA:3.40.50.720 1 161 1.9E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 SUPERFAMILY SSF51735 1 143 4.67E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 SUPERFAMILY SSF48179 158 290 5.31E-41 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PANTHER PTHR11811 1 291 5.2E-165 T 16-09-2016 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 4.7E-26 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 SMART SM01350 160 291 4.3E-6 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 7.0E-102 T 16-09-2016 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PANTHER PTHR11811:SF28 1 291 5.2E-165 T 16-09-2016 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 Gene3D G3DSA:1.10.1040.10 162 270 8.5E-36 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 5.5E-36 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 6.3E-36 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 6.3E-36 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 6.3E-36 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 6.3E-36 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS16580 2734a6fc6ef22ab352b78ba2516e044a 291 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 6.3E-36 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 Gene3D G3DSA:3.40.50.2300 325 375 1.6E-17 T 16-09-2016 Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 Gene3D G3DSA:3.40.50.2300 52 175 1.6E-17 T 16-09-2016 Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 PANTHER PTHR30483:SF20 1 423 2.1E-133 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 SUPERFAMILY SSF53822 55 379 1.41E-26 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 PANTHER PTHR30483 1 423 2.1E-133 T 16-09-2016 Spa2297_RS14420 55793e2c7ea4e33d274ca3301f1e778a 438 Pfam PF13458 Periplasmic binding protein 70 389 4.9E-24 T 16-09-2016 IPR028081 Leucine-binding protein domain Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 Gene3D G3DSA:3.20.20.70 7 355 4.4E-111 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 SUPERFAMILY SSF51569 7 299 1.26E-75 T 16-09-2016 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 Pfam PF08502 LeuA allosteric (dimerisation) domain 382 523 2.9E-27 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 SMART SM00917 382 525 1.1E-35 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 PANTHER PTHR10277:SF5 5 533 6.9E-267 T 16-09-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 Pfam PF00682 HMGL-like 12 277 1.5E-44 T 16-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 PANTHER PTHR10277 5 533 6.9E-267 T 16-09-2016 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 11 527 1.5E-191 T 16-09-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 SUPERFAMILY SSF110921 405 520 5.1E-20 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS23410 f526cee6273df0c797f49e3c6cd0eadf 534 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 18 34 - T 16-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PANTHER PTHR22600 3 199 4.2E-189 T 16-09-2016 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PANTHER PTHR22600 216 508 4.2E-189 T 16-09-2016 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PANTHER PTHR22600:SF21 3 199 4.2E-189 T 16-09-2016 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 8 135 2.6E-20 T 16-09-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 SUPERFAMILY SSF55545 4 138 1.83E-27 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PANTHER PTHR22600:SF21 216 508 4.2E-189 T 16-09-2016 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 SUPERFAMILY SSF51445 140 492 3.16E-101 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 Gene3D G3DSA:3.20.20.80 137 508 3.3E-113 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 140 481 1.1E-99 T 16-09-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 463 480 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 233 250 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 90 110 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 162 183 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 303 316 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 445 461 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 PRINTS PR00738 Glycosyl hydrolase family 20 signature 133 150 8.7E-44 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS30940 3af33c62d11dcc05bd1a0009d4269bc9 538 Gene3D G3DSA:3.30.379.10 6 135 2.9E-30 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS04300 ff90d1b3c85ae366fcf6c7a80fe439d1 122 PIRSF PIRSF009151 1 122 6.2E-58 T 16-09-2016 IPR008497 Protein of unknown function DUF779 Spa2297_RS04300 ff90d1b3c85ae366fcf6c7a80fe439d1 122 Pfam PF05610 Protein of unknown function (DUF779) 20 119 1.2E-46 T 16-09-2016 IPR008497 Protein of unknown function DUF779 Spa2297_RS16020 a2605de84f09d4e9bf3d9c0aa87f7594 126 PANTHER PTHR33495:SF2 12 125 2.7E-24 T 16-09-2016 Spa2297_RS16020 a2605de84f09d4e9bf3d9c0aa87f7594 126 PANTHER PTHR33495 12 125 2.7E-24 T 16-09-2016 Spa2297_RS16020 a2605de84f09d4e9bf3d9c0aa87f7594 126 Pfam PF01740 STAS domain 15 117 8.0E-12 T 16-09-2016 IPR002645 STAS domain Spa2297_RS16020 a2605de84f09d4e9bf3d9c0aa87f7594 126 SUPERFAMILY SSF52091 17 119 7.26E-16 T 16-09-2016 IPR002645 STAS domain Spa2297_RS16020 a2605de84f09d4e9bf3d9c0aa87f7594 126 Gene3D G3DSA:3.30.750.24 15 119 2.8E-17 T 16-09-2016 IPR002645 STAS domain Spa2297_RS20015 09cc4a7a167a9a1fc711181b9c1f8c5a 174 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 22 143 2.1E-30 T 16-09-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Spa2297_RS20015 09cc4a7a167a9a1fc711181b9c1f8c5a 174 PANTHER PTHR33540 18 172 4.9E-41 T 16-09-2016 Spa2297_RS20015 09cc4a7a167a9a1fc711181b9c1f8c5a 174 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 25 145 1.3E-26 T 16-09-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Spa2297_RS20015 09cc4a7a167a9a1fc711181b9c1f8c5a 174 Gene3D G3DSA:3.40.50.300 18 167 6.0E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20015 09cc4a7a167a9a1fc711181b9c1f8c5a 174 SUPERFAMILY SSF52540 38 143 4.18E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 1.4E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 PANTHER PTHR30055 3 196 1.2E-106 T 16-09-2016 Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 SUPERFAMILY SSF46689 8 69 1.18E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 PANTHER PTHR30055:SF6 3 196 1.2E-106 T 16-09-2016 Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 189 2.3E-30 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 SUPERFAMILY SSF48498 81 192 7.71E-22 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 Gene3D G3DSA:1.10.357.10 62 193 1.7E-30 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS13780 65a91eeaf0d447a4ac2eebc61f456ec8 203 Gene3D G3DSA:1.10.10.60 7 61 9.1E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS08120 8f5b94133f08968c57247831109f8e84 596 Pfam PF13406 Transglycosylase SLT domain 173 226 6.5E-8 T 16-09-2016 IPR031304 Transglycosylase SLT domain 2 Spa2297_RS08120 8f5b94133f08968c57247831109f8e84 596 Gene3D G3DSA:1.10.530.10 173 250 3.6E-13 T 16-09-2016 Spa2297_RS08120 8f5b94133f08968c57247831109f8e84 596 Gene3D G3DSA:1.10.530.10 106 136 3.6E-13 T 16-09-2016 Spa2297_RS08120 8f5b94133f08968c57247831109f8e84 596 SUPERFAMILY SSF53955 51 258 1.22E-41 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS27290 1ddd584c31a571553a3e42784b232a1b 336 PANTHER PTHR18640:SF9 1 314 1.8E-100 T 16-09-2016 Spa2297_RS27290 1ddd584c31a571553a3e42784b232a1b 336 PANTHER PTHR18640 1 314 1.8E-100 T 16-09-2016 IPR016833 Putative sodium bile acid cotransporter Spa2297_RS27290 1ddd584c31a571553a3e42784b232a1b 336 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 5 308 9.8E-89 T 16-09-2016 IPR016833 Putative sodium bile acid cotransporter Spa2297_RS27290 1ddd584c31a571553a3e42784b232a1b 336 PIRSF PIRSF026166 1 327 1.6E-123 T 16-09-2016 IPR016833 Putative sodium bile acid cotransporter Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 114 125 - T 16-09-2016 IPR018215 ClpP, Ser active site Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 SUPERFAMILY SSF52096 35 219 1.86E-62 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 27 218 39.317 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 136 149 - T 16-09-2016 IPR033135 ClpP, histidine active site Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 Pfam PF00574 Clp protease 37 217 8.8E-77 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 Gene3D G3DSA:3.90.226.10 28 218 1.8E-74 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PANTHER PTHR10381 20 218 1.7E-140 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PRINTS PR00127 Clp protease catalytic subunit P signature 135 154 1.3E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PRINTS PR00127 Clp protease catalytic subunit P signature 193 212 1.3E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PRINTS PR00127 Clp protease catalytic subunit P signature 43 58 1.3E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PRINTS PR00127 Clp protease catalytic subunit P signature 114 131 1.3E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PRINTS PR00127 Clp protease catalytic subunit P signature 83 103 1.3E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11070 bb1e60c48a1e0c33b21d1f933bb69496 226 PANTHER PTHR10381:SF7 20 218 1.7E-140 T 16-09-2016 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 36 328 4.4E-88 T 16-09-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 PANTHER PTHR30425 1 335 6.0E-147 T 16-09-2016 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 Gene3D G3DSA:1.10.3720.10 47 331 2.7E-36 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 SUPERFAMILY SSF161098 58 320 3.66E-32 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 328 1.5E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS15470 078f970b1c9fa87a5f1a1509eedf7a99 336 PANTHER PTHR30425:SF1 1 335 6.0E-147 T 16-09-2016 Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 Gene3D G3DSA:3.40.50.720 1 226 5.9E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 114 122 2.5E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 60 71 2.5E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 153 2.5E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 172 8.7E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 108 124 8.7E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 60 71 8.7E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 208 8.7E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 153 8.7E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 SUPERFAMILY SSF51735 1 226 1.0E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 1 225 2.9E-53 T 16-09-2016 Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PANTHER PTHR24322 1 118 8.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11965 ad3dad2fb472c90557fc9ec321010627 227 PANTHER PTHR24322 134 165 8.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 543 670 1.5E-38 T 16-09-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 SUPERFAMILY SSF52242 520 665 4.84E-44 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 SUPERFAMILY SSF51703 12 504 7.06E-163 T 16-09-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 Gene3D G3DSA:3.20.20.240 10 503 1.1E-187 T 16-09-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 PANTHER PTHR23408 11 649 0.0 T 16-09-2016 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 Pfam PF02310 B12 binding domain 545 651 6.3E-17 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 14 508 2.9E-139 T 16-09-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 Gene3D G3DSA:3.40.50.280 519 663 7.9E-48 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 PANTHER PTHR23408:SF15 11 649 0.0 T 16-09-2016 Spa2297_RS26930 954550307590e1c705988ceb0a9b146f 682 Pfam PF01642 Methylmalonyl-CoA mutase 11 502 1.1E-130 T 16-09-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Spa2297_RS05200 7abcec537ec3883796ca10eb6003ca35 107 PANTHER PTHR21496:SF11 1 97 1.4E-24 T 16-09-2016 Spa2297_RS05200 7abcec537ec3883796ca10eb6003ca35 107 SUPERFAMILY SSF50022 2 100 1.44E-29 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05200 7abcec537ec3883796ca10eb6003ca35 107 Gene3D G3DSA:2.102.10.10 2 102 1.1E-29 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05200 7abcec537ec3883796ca10eb6003ca35 107 Pfam PF00355 Rieske [2Fe-2S] domain 2 85 1.6E-16 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05200 7abcec537ec3883796ca10eb6003ca35 107 PANTHER PTHR21496 1 97 1.4E-24 T 16-09-2016 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 SUPERFAMILY SSF46689 265 314 8.51E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 SMART SM00342 228 311 2.0E-25 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 SUPERFAMILY SSF52317 7 194 4.01E-41 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 Gene3D G3DSA:1.10.10.60 266 313 1.4E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 Gene3D G3DSA:3.40.50.880 7 191 2.5E-46 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 SUPERFAMILY SSF46689 212 262 8.24E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 Gene3D G3DSA:1.10.10.60 207 265 4.3E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 PANTHER PTHR11019 5 318 9.4E-102 T 16-09-2016 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 Pfam PF01965 DJ-1/PfpI family 7 172 4.0E-22 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 Pfam PF12833 Helix-turn-helix domain 234 312 1.7E-20 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 PANTHER PTHR11019:SF68 5 318 9.4E-102 T 16-09-2016 Spa2297_RS01185 445c3a3ce24c0096042d7aa698adab20 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 3.2E-55 T 16-09-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Gene3D G3DSA:2.30.30.30 120 196 4.2E-30 T 16-09-2016 IPR014722 Ribosomal protein L2 domain 2 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 SMART SM01383 42 119 1.8E-39 T 16-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 PANTHER PTHR13691 1 278 3.6E-138 T 16-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.792 T 16-09-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Gene3D G3DSA:4.10.950.10 197 273 9.9E-33 T 16-09-2016 IPR014726 Ribosomal protein L2, domain 3 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 SUPERFAMILY SSF50249 3 126 1.13E-48 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.6E-32 T 16-09-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.1E-127 T 16-09-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 SUPERFAMILY SSF50104 127 271 2.29E-56 T 16-09-2016 IPR008991 Translation protein SH3-like domain Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 Gene3D G3DSA:2.40.50.140 1 115 3.6E-51 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 PIRSF PIRSF002158 4 275 1.1E-93 T 16-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 16-09-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19810 ef4a12fa0956b931236cb9dca5f2cfab 278 SMART SM01382 125 253 4.3E-89 T 16-09-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS20450 43f609c350d47b925acd7a518057cfa5 316 PANTHER PTHR11048 6 223 2.3E-88 T 16-09-2016 Spa2297_RS20450 43f609c350d47b925acd7a518057cfa5 316 Pfam PF01040 UbiA prenyltransferase family 47 278 3.4E-15 T 16-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 Spa2297_RS20450 43f609c350d47b925acd7a518057cfa5 316 PANTHER PTHR11048:SF5 6 223 2.3E-88 T 16-09-2016 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 Pfam PF00005 ABC transporter 372 521 1.7E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 Pfam PF00664 ABC transporter transmembrane region 46 313 2.1E-26 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 Gene3D G3DSA:1.20.1560.10 35 346 3.4E-50 T 16-09-2016 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 Gene3D G3DSA:3.40.50.300 357 586 5.0E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 SMART SM00382 381 567 2.7E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 PANTHER PTHR24221:SF221 35 593 0.0 T 16-09-2016 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 PANTHER PTHR24221 35 593 0.0 T 16-09-2016 Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 SUPERFAMILY SSF52540 353 591 6.17E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04100 0e67307d433ca91236206db62c0e6c5d 593 SUPERFAMILY SSF90123 35 347 2.62E-52 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 SMART SM00422 11 80 9.4E-21 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 PANTHER PTHR30204:SF13 3 235 1.6E-44 T 16-09-2016 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 1.5E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.5E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.5E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 PANTHER PTHR30204 3 235 1.6E-44 T 16-09-2016 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 SUPERFAMILY SSF46955 11 87 1.06E-17 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 Pfam PF13411 MerR HTH family regulatory protein 12 78 5.0E-19 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28040 b1c679e536a0dc6d3fd3855cafa4a09f 246 Gene3D G3DSA:1.10.1660.10 11 83 7.4E-19 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423 6 12 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423 91 127 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 272 2.5E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423:SF427 6 12 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423:SF427 91 127 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 SUPERFAMILY SSF55874 263 422 6.02E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 SUPERFAMILY SSF47384 198 271 4.12E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 Gene3D G3DSA:1.10.287.130 205 260 1.5E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 SMART SM00304 158 214 2.5E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 SMART SM00388 215 273 3.9E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 Gene3D G3DSA:3.30.565.10 261 421 5.0E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423:SF427 194 405 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 PANTHER PTHR24423 194 405 5.0E-36 T 16-09-2016 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 Pfam PF00672 HAMP domain 139 210 1.1E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 422 2.5E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18375 980478c35a302b53a00907476c699cc9 443 SMART SM00387 311 424 2.8E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 Gene3D G3DSA:2.60.40.650 428 531 1.6E-22 T 16-09-2016 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 Gene3D G3DSA:3.90.420.10 233 427 1.8E-50 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 SUPERFAMILY SSF56524 235 429 9.42E-52 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 Pfam PF00174 Oxidoreductase molybdopterin binding domain 253 411 4.2E-35 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 PANTHER PTHR19372 235 512 2.3E-77 T 16-09-2016 Spa2297_RS30810 7c1a3813c756280ca91127c0055ead87 532 SUPERFAMILY SSF81296 422 531 1.4E-24 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 SUPERFAMILY SSF103473 26 430 5.62E-40 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 PANTHER PTHR23515 5 350 5.5E-228 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 PANTHER PTHR23515 369 443 5.5E-228 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 PANTHER PTHR23515:SF6 5 350 5.5E-228 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 PANTHER PTHR23515:SF6 369 443 5.5E-228 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 Pfam PF07690 Major Facilitator Superfamily 42 388 2.2E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 Gene3D G3DSA:1.20.1250.20 228 428 1.1E-15 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 Gene3D G3DSA:1.20.1250.20 30 212 1.8E-12 T 16-09-2016 Spa2297_RS12780 30f14e0355a78c45f9ed86a59d243d08 453 TIGRFAM TIGR00886 2A0108: nitrite transporter 30 387 1.6E-95 T 16-09-2016 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 299 325 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 130 143 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PANTHER PTHR30603 14 337 2.1E-123 T 16-09-2016 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PANTHER PTHR30603:SF0 14 337 2.1E-123 T 16-09-2016 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Gene3D G3DSA:1.10.601.10 23 175 6.1E-56 T 16-09-2016 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 102 326 9.5E-32 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Pfam PF04539 Sigma-70 region 3 185 259 4.8E-18 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Pfam PF04545 Sigma-70, region 4 276 327 5.5E-15 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Gene3D G3DSA:1.10.10.10 270 336 2.6E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Pfam PF04542 Sigma-70 region 2 106 175 3.3E-19 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Gene3D G3DSA:1.10.10.10 179 228 2.2E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 SUPERFAMILY SSF88659 236 329 3.74E-21 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 Pfam PF00140 Sigma-70 factor, region 1.2 37 69 2.8E-11 T 16-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 SUPERFAMILY SSF88659 179 252 1.0E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PRINTS PR00046 Major sigma-70 factor signature 154 162 1.8E-23 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PRINTS PR00046 Major sigma-70 factor signature 278 290 1.8E-23 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PRINTS PR00046 Major sigma-70 factor signature 299 314 1.8E-23 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PRINTS PR00046 Major sigma-70 factor signature 314 325 1.8E-23 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 PRINTS PR00046 Major sigma-70 factor signature 130 143 1.8E-23 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29145 3bdca6c7fadd94b2b7377a78907d44f8 339 SUPERFAMILY SSF88946 36 176 1.07E-47 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 Pfam PF00072 Response regulator receiver domain 7 116 5.6E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 SMART SM00862 161 232 1.3E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 SUPERFAMILY SSF46894 139 232 7.65E-28 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 SMART SM00448 5 115 1.5E-39 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 Gene3D G3DSA:1.10.10.10 140 233 1.2E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 232 1.4E-23 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 Gene3D G3DSA:3.40.50.2300 3 121 2.9E-38 T 16-09-2016 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 PANTHER PTHR26402:SF509 5 234 9.0E-138 T 16-09-2016 Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 SUPERFAMILY SSF52172 3 123 2.99E-39 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS18380 d0d7cba4a25870146c24640efcf1d505 234 PANTHER PTHR26402 5 234 9.0E-138 T 16-09-2016 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 SUPERFAMILY SSF53738 7 168 1.61E-29 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Gene3D G3DSA:3.30.310.50 373 453 1.2E-21 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 5.2E-22 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 207 220 5.2E-22 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 5.2E-22 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 5.2E-22 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Gene3D G3DSA:3.40.120.10 175 252 2.5E-33 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 SUPERFAMILY SSF53738 156 258 1.02E-30 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 256 4.2E-27 T 16-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PANTHER PTHR22573 7 454 1.6E-182 T 16-09-2016 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 SUPERFAMILY SSF53738 264 367 5.89E-28 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 265 371 9.9E-25 T 16-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 SUPERFAMILY SSF55957 374 454 4.71E-19 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 PANTHER PTHR22573:SF28 7 454 1.6E-182 T 16-09-2016 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 453 5.2E-14 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 133 2.7E-28 T 16-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Gene3D G3DSA:3.40.120.10 9 131 6.7E-25 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS13105 5b930cc4cb1171697b27eb6c5506390c 454 Gene3D G3DSA:3.40.120.10 253 371 7.7E-35 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 Pfam PF00106 short chain dehydrogenase 8 194 4.4E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 0.0026 T 16-09-2016 Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PANTHER PTHR24322:SF631 10 138 4.9E-40 T 16-09-2016 Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PANTHER PTHR24322:SF631 154 186 4.9E-40 T 16-09-2016 Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.8E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.3E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.3E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PANTHER PTHR24322 10 138 4.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 PANTHER PTHR24322 154 186 4.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 SUPERFAMILY SSF51735 7 230 2.08E-55 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31850 3c67aa054060863acb8304044d28a30c 266 Gene3D G3DSA:3.40.50.720 7 216 2.0E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 Gene3D G3DSA:3.40.50.300 230 436 7.5E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 PANTHER PTHR30473 12 441 1.1E-193 T 16-09-2016 Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 PANTHER PTHR30473:SF2 12 441 1.1E-193 T 16-09-2016 Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 Pfam PF13638 PIN domain 15 153 2.3E-26 T 16-09-2016 IPR002716 PIN domain Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 SMART SM00670 13 140 8.4E-14 T 16-09-2016 IPR002716 PIN domain Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 SUPERFAMILY SSF52540 230 393 5.87E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 Gene3D G3DSA:3.40.50.1010 105 153 2.6E-10 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 Gene3D G3DSA:3.40.50.1010 14 72 2.6E-10 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 SUPERFAMILY SSF88723 105 151 8.97E-9 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 SUPERFAMILY SSF88723 14 72 8.97E-9 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS21280 6e2507bcc8949a48cde2c80184963529 441 Pfam PF02562 PhoH-like protein 231 436 1.2E-53 T 16-09-2016 IPR003714 PhoH-like protein GO:0005524 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 Gene3D G3DSA:3.40.1130.10 84 167 2.2E-5 T 16-09-2016 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 Pfam PF01553 Acyltransferase 74 194 7.0E-19 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 SUPERFAMILY SSF69593 39 195 2.62E-22 T 16-09-2016 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 SMART SM00563 86 198 1.3E-28 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 PANTHER PTHR10434:SF8 1 198 1.1E-67 T 16-09-2016 Spa2297_RS29035 87f5a9a0a04aeaf0076cf2a92f40b999 281 PANTHER PTHR10434 1 198 1.1E-67 T 16-09-2016 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 PIRSF PIRSF006603 10 445 1.3E-64 T 16-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 PANTHER PTHR11206 9 438 1.7E-132 T 16-09-2016 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 Pfam PF01554 MatE 25 185 6.9E-28 T 16-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 Pfam PF01554 MatE 243 394 4.9E-20 T 16-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 PANTHER PTHR11206:SF94 9 438 1.7E-132 T 16-09-2016 Spa2297_RS16420 318fb1fb11ddd6cdb3b435fbf2c5c80b 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 3.5E-107 T 16-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 Spa2297_RS20895 f47397daa1c13741a7707c5d3e48efa5 414 PANTHER PTHR30582:SF2 77 413 1.5E-106 T 16-09-2016 Spa2297_RS20895 f47397daa1c13741a7707c5d3e48efa5 414 Gene3D G3DSA:2.40.440.10 253 385 1.3E-19 T 16-09-2016 Spa2297_RS20895 f47397daa1c13741a7707c5d3e48efa5 414 SUPERFAMILY SSF141523 253 384 6.93E-22 T 16-09-2016 Spa2297_RS20895 f47397daa1c13741a7707c5d3e48efa5 414 PANTHER PTHR30582 77 413 1.5E-106 T 16-09-2016 Spa2297_RS20895 f47397daa1c13741a7707c5d3e48efa5 414 Pfam PF03734 L,D-transpeptidase catalytic domain 251 360 1.6E-12 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 9.5E-91 T 16-09-2016 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 16-09-2016 IPR020583 Inositol monophosphatase, metal-binding site Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PANTHER PTHR20854:SF38 1 262 3.1E-97 T 16-09-2016 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 5.1E-12 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 5.1E-12 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 5.1E-12 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 5.1E-12 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 Gene3D G3DSA:3.40.190.80 158 264 6.8E-24 T 16-09-2016 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 SUPERFAMILY SSF56655 3 264 1.05E-73 T 16-09-2016 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 Pfam PF00459 Inositol monophosphatase family 11 264 1.6E-45 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 Gene3D G3DSA:3.30.540.10 4 157 2.1E-42 T 16-09-2016 Spa2297_RS22020 a48f0baf4d8537508e75ed9b8df4d729 266 PANTHER PTHR20854 1 262 3.1E-97 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS08670 0b65801903a733bfe350557ffc65cdb0 215 SUPERFAMILY SSF56524 20 208 7.32E-53 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS08670 0b65801903a733bfe350557ffc65cdb0 215 Pfam PF00174 Oxidoreductase molybdopterin binding domain 38 186 3.9E-27 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS08670 0b65801903a733bfe350557ffc65cdb0 215 Gene3D G3DSA:3.90.420.10 17 204 3.7E-45 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS08670 0b65801903a733bfe350557ffc65cdb0 215 PANTHER PTHR19372 11 205 5.3E-66 T 16-09-2016 Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 Pfam PF07690 Major Facilitator Superfamily 8 327 3.4E-40 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 Gene3D G3DSA:1.20.1250.20 201 381 1.5E-11 T 16-09-2016 Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 PANTHER PTHR23501 1 397 1.5E-170 T 16-09-2016 Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 PANTHER PTHR23501:SF4 1 397 1.5E-170 T 16-09-2016 Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 SUPERFAMILY SSF103473 3 380 9.68E-58 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16395 d3dcf6c9f66b0534e18053c546d791be 404 Gene3D G3DSA:1.20.1250.20 5 186 1.1E-27 T 16-09-2016 Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 Pfam PF13622 Thioesterase-like superfamily 33 284 1.2E-59 T 16-09-2016 Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 SUPERFAMILY SSF54637 116 287 4.18E-46 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 Gene3D G3DSA:3.10.129.10 125 287 5.5E-51 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 PANTHER PTHR11066:SF34 1 289 1.3E-111 T 16-09-2016 Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 SUPERFAMILY SSF54637 5 114 2.16E-42 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 PANTHER PTHR11066 1 289 1.3E-111 T 16-09-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Spa2297_RS11740 95558abc4dbdd882044c1a07a6dc8d9b 290 Gene3D G3DSA:3.10.129.10 5 115 2.0E-48 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SMART SM00388 115 179 2.7E-8 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 273 2.9E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 331 2.9E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 312 2.9E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SMART SM00304 61 114 4.3E-12 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 332 1.1E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 Pfam PF00672 HAMP domain 42 110 1.1E-15 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 Gene3D G3DSA:3.30.565.10 182 333 1.0E-26 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SUPERFAMILY SSF47384 98 178 5.49E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 PANTHER PTHR24423 56 331 1.8E-52 T 16-09-2016 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 Pfam PF00512 His Kinase A (phospho-acceptor) domain 116 178 5.7E-8 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 Gene3D G3DSA:1.10.287.130 105 175 1.9E-9 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SUPERFAMILY SSF158472 62 111 6.41E-9 T 16-09-2016 Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SUPERFAMILY SSF55874 170 332 5.37E-28 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16660 46314310a3fbf50461e37b51113eeb40 334 SMART SM00387 221 334 7.7E-18 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 PANTHER PTHR14741 118 307 5.0E-38 T 16-09-2016 Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 Pfam PF13649 Methyltransferase domain 138 205 4.2E-7 T 16-09-2016 Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 SUPERFAMILY SSF53335 104 265 3.01E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 Gene3D G3DSA:3.40.50.150 109 209 1.4E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 Gene3D G3DSA:3.40.50.150 365 378 1.4E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20065 b1dfdc20aad1c240b8d227b2cc784919 429 Gene3D G3DSA:3.40.50.150 332 333 1.4E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 Pfam PF00005 ABC transporter 19 164 2.5E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 363 1.2E-98 T 16-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 Gene3D G3DSA:3.10.580.10 258 362 8.5E-11 T 16-09-2016 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 SMART SM00382 27 214 6.4E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 SUPERFAMILY SSF52540 1 239 2.93E-75 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 Gene3D G3DSA:3.40.50.300 1 237 2.3E-75 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 PANTHER PTHR24220 3 252 2.9E-139 T 16-09-2016 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 SUPERFAMILY SSF54631 254 362 2.79E-11 T 16-09-2016 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 PANTHER PTHR24220:SF350 3 252 2.9E-139 T 16-09-2016 Spa2297_RS29615 7e73f6b2ba6b9124639f2d08948c6361 384 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS00735 93f22ed86445dac41a872c412abf6607 411 SUPERFAMILY SSF51445 273 332 1.83E-13 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00735 93f22ed86445dac41a872c412abf6607 411 SUPERFAMILY SSF51445 136 234 1.83E-13 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00735 93f22ed86445dac41a872c412abf6607 411 Pfam PF02156 Glycosyl hydrolase family 26 173 229 2.0E-4 T 16-09-2016 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 Spa2297_RS00735 93f22ed86445dac41a872c412abf6607 411 Gene3D G3DSA:3.20.20.80 268 332 2.0E-15 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS00735 93f22ed86445dac41a872c412abf6607 411 Gene3D G3DSA:3.20.20.80 83 235 2.0E-15 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS29590 f35c05dc46d96b93d578c58eda445d94 436 PANTHER PTHR30489 51 178 1.8E-14 T 16-09-2016 Spa2297_RS29590 f35c05dc46d96b93d578c58eda445d94 436 Pfam PF02687 FtsX-like permease family 313 426 1.6E-7 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS29590 f35c05dc46d96b93d578c58eda445d94 436 Pfam PF02687 FtsX-like permease family 65 177 1.1E-12 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Gene3D G3DSA:1.25.40.10 102 212 1.4E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Gene3D G3DSA:1.25.40.10 633 666 1.4E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 76 9.3E-9 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SMART SM00862 15 87 3.1E-9 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Gene3D G3DSA:3.40.50.300 255 303 4.2E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 PANTHER PTHR35807 1 321 1.3E-42 T 16-09-2016 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Pfam PF13191 AAA ATPase domain 257 421 5.5E-8 T 16-09-2016 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SMART SM01043 94 233 3.2E-43 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SUPERFAMILY SSF46894 15 87 8.22E-11 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Pfam PF03704 Bacterial transcriptional activator domain 94 233 2.9E-39 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SUPERFAMILY SSF48452 92 247 9.97E-30 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Gene3D G3DSA:1.25.40.10 836 1063 1.2E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SUPERFAMILY SSF52540 252 510 3.91E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 SUPERFAMILY SSF48452 836 967 1.66E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15615 d1d588668e84945f04dcb13bed29bf73 1092 Gene3D G3DSA:1.10.10.10 23 89 6.9E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 Gene3D G3DSA:3.40.50.720 1 182 3.3E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 SUPERFAMILY SSF51735 1 178 3.83E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 PIRSF PIRSF000105 1 278 8.9E-76 T 16-09-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 Gene3D G3DSA:1.10.1040.10 183 277 1.9E-33 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 SUPERFAMILY SSF48179 181 277 5.27E-30 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 178 3.6E-57 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 PANTHER PTHR23309 1 277 1.5E-169 T 16-09-2016 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 PANTHER PTHR23309:SF24 1 277 1.5E-169 T 16-09-2016 Spa2297_RS06120 0b13e2490511f6950b203bb76c24e70b 278 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 277 2.6E-32 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 4.1E-50 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 5.0E-46 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 PANTHER PTHR21012 2 133 1.8E-71 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 Gene3D G3DSA:2.40.40.20 1 117 1.7E-55 T 16-09-2016 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 Pfam PF02261 Aspartate decarboxylase 1 114 1.8E-51 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 SUPERFAMILY SSF50692 1 115 8.08E-49 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 PIRSF PIRSF006246 1 136 6.0E-53 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 129 74.58 T 16-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 Spa2297_RS28810 d3461654604faf3126129e22888ac0a6 139 PANTHER PTHR21012:SF0 2 133 1.8E-71 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Pfam PF00550 Phosphopantetheine attachment site 188 250 1.4E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Gene3D G3DSA:2.30.38.10 5 69 1.2E-22 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 ProSitePatterns PS00012 Phosphopantetheine attachment site. 209 224 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Pfam PF13193 AMP-binding enzyme C-terminal domain 87 160 4.2E-17 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 SUPERFAMILY SSF47336 179 250 7.33E-20 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Gene3D G3DSA:3.30.300.30 74 189 1.2E-45 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Pfam PF00668 Condensation domain 268 381 6.9E-25 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 SMART SM00823 Phosphopantetheine attachment site 185 254 6.7E-5 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 SUPERFAMILY SSF52777 271 382 3.34E-27 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 PANTHER PTHR24095:SF137 5 382 1.3E-162 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Gene3D G3DSA:1.10.1200.10 190 253 2.5E-26 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 SUPERFAMILY SSF56801 5 198 7.59E-71 T 16-09-2016 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 Pfam PF00501 AMP-binding enzyme 5 79 9.3E-23 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS34285 880bc35c079ae057e90d8d8901b4f6e1 382 PANTHER PTHR24095 5 382 1.3E-162 T 16-09-2016 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 Gene3D G3DSA:1.20.1250.20 41 227 9.2E-29 T 16-09-2016 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 Pfam PF00083 Sugar (and other) transporter 73 483 7.7E-45 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 Gene3D G3DSA:1.20.1250.20 284 482 6.6E-16 T 16-09-2016 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 PANTHER PTHR24064 22 483 8.9E-100 T 16-09-2016 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 PANTHER PTHR24064:SF172 22 483 8.9E-100 T 16-09-2016 Spa2297_RS12345 3dab2a1925ab725a362b7dd4c794fc7b 496 SUPERFAMILY SSF103473 22 482 7.06E-72 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02395 b22e9cce7e79b76094ec20a1ab8a2ec2 227 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 191 221 3.9E-4 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS02395 b22e9cce7e79b76094ec20a1ab8a2ec2 227 Pfam PF03777 Small secreted domain (DUF320) 19 74 2.0E-27 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS02395 b22e9cce7e79b76094ec20a1ab8a2ec2 227 Pfam PF03777 Small secreted domain (DUF320) 92 147 5.6E-23 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Gene3D G3DSA:1.10.287.80 20 61 1.0E-27 T 16-09-2016 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Gene3D G3DSA:1.10.287.80 211 244 1.0E-27 T 16-09-2016 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 PANTHER PTHR11693 3 298 5.7E-104 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 SUPERFAMILY SSF52943 3 296 3.14E-79 T 16-09-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Gene3D G3DSA:1.10.287.80 245 291 7.2E-25 T 16-09-2016 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 282 295 - T 16-09-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 296 4.8E-91 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Gene3D G3DSA:3.40.1380.10 64 197 1.9E-38 T 16-09-2016 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 296 33.338 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 2.7E-30 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.7E-30 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 2.7E-30 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 2.7E-30 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS22695 bde0252e238c7710395f922ca977eb42 305 Pfam PF00231 ATP synthase 5 296 1.6E-83 T 16-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 Pfam PF11066 Protein of unknown function (DUF2867) 352 497 8.5E-40 T 16-09-2016 IPR021295 Protein of unknown function DUF2867 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 SUPERFAMILY SSF55961 361 507 1.78E-8 T 16-09-2016 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 PANTHER PTHR10366:SF401 22 261 3.2E-107 T 16-09-2016 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 PANTHER PTHR10366:SF401 282 299 3.2E-107 T 16-09-2016 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 SUPERFAMILY SSF51735 20 287 1.1E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 PANTHER PTHR10366 22 261 3.2E-107 T 16-09-2016 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 PANTHER PTHR10366 282 299 3.2E-107 T 16-09-2016 Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 Pfam PF13460 NAD(P)H-binding 27 170 3.2E-24 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29490 fa37b12a402b1761c728c85f26c5bcbe 512 Gene3D G3DSA:3.40.50.720 19 241 7.9E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 2714 2960 1.45E-60 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF56801 3837 3912 4.19E-157 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF56801 2956 3445 4.19E-157 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00501 AMP-binding enzyme 1523 1925 3.8E-105 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00501 AMP-binding enzyme 463 866 5.8E-93 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00501 AMP-binding enzyme 2996 3391 1.8E-97 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 ProSitePatterns PS00012 Phosphopantetheine attachment site. 996 1011 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 3160 3301 4.1E-36 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.150 2004 2175 6.1E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.150 3470 3648 4.8E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.30.300.30 2385 2447 7.8E-39 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.30.300.30 3842 3904 1.5E-37 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.30.300.30 3386 3441 1.5E-37 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.30.300.30 1920 1974 7.8E-39 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.30.300.30 861 976 3.7E-44 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 2992 3159 3.0E-48 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095:SF137 1424 1964 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 458 609 9.1E-48 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 1521 1677 6.2E-45 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3017 3415 2.2E-131 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1544 1949 2.2E-135 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 890 8.2E-138 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 6 204 1.56E-43 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095 1424 1964 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095 635 1407 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 610 777 1.8E-33 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.980 1678 1836 1.0E-39 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 2529 2701 2.89E-50 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF47336 966 1037 1.7E-18 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 1241 1487 9.23E-61 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095 2372 3448 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF47336 2438 2508 2.09E-18 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1673 1684 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF47336 3893 3965 2.75E-19 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:1.10.1200.10 2448 2511 6.4E-25 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:1.10.1200.10 3905 3967 1.7E-25 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:1.10.1200.10 977 1040 5.6E-25 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF53474 3967 4223 3.59E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13745 HxxPF-repeated domain 2847 2942 1.4E-30 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13745 HxxPF-repeated domain 1374 1469 2.8E-30 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2467 2482 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 1058 1228 1.33E-50 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3136 3147 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF52777 189 434 1.78E-57 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF53335 3470 3613 6.29E-27 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00668 Condensation domain 1055 1352 3.6E-68 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00668 Condensation domain 2526 2825 1.4E-63 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00668 Condensation domain 7 303 2.6E-68 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 ProSitePatterns PS00455 Putative AMP-binding domain signature. 604 615 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00975 Thioesterase domain 3988 4223 8.8E-31 T 16-09-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.1820 4166 4233 1.4E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:3.40.50.1820 3973 4091 1.4E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF53335 2005 2158 1.43E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SMART SM00823 Phosphopantetheine attachment site 2443 2512 8.1E-8 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SMART SM00823 Phosphopantetheine attachment site 972 1041 6.7E-5 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SMART SM00823 Phosphopantetheine attachment site 3900 3969 5.5E-7 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:2.30.38.10 1837 1915 5.1E-27 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:2.30.38.10 778 856 1.6E-27 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Gene3D G3DSA:2.30.38.10 3302 3381 3.6E-26 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13649 Methyltransferase domain 3506 3605 2.7E-12 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13649 Methyltransferase domain 2042 2141 1.2E-11 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF56801 2380 2456 3.66E-158 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF56801 1483 1979 3.66E-158 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00550 Phosphopantetheine attachment site 975 1037 2.7E-15 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00550 Phosphopantetheine attachment site 2447 2508 8.2E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF00550 Phosphopantetheine attachment site 3902 3965 1.2E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SMART SM00824 Thioesterase 3990 4228 2.2E-5 T 16-09-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095:SF137 2372 3448 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 PANTHER PTHR24095:SF137 635 1407 0.0 T 16-09-2016 Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13193 AMP-binding enzyme C-terminal domain 3399 3444 1.6E-5 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 947 8.9E-16 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02680 c481a9f951491b667e7bdc586c6c341c 4239 SUPERFAMILY SSF56801 449 985 1.83E-157 T 16-09-2016 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.0E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 7.0E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 PRINTS PR00400 Tetracycline repressor protein signature 34 57 8.8E-5 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 PRINTS PR00400 Tetracycline repressor protein signature 204 218 8.8E-5 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 PANTHER PTHR30055 5 130 4.4E-18 T 16-09-2016 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 Gene3D G3DSA:1.10.357.10 8 218 3.2E-48 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 SUPERFAMILY SSF48498 87 218 4.11E-18 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 SUPERFAMILY SSF46689 12 78 1.03E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 65 1.7E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02575 61d77728fdc41c54f0823c0fb38b7445 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 220 2.3E-11 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 375 150.951 T 16-09-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 Gene3D G3DSA:2.40.50.140 18 65 6.3E-11 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 Gene3D G3DSA:3.40.50.300 91 371 7.2E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 SUPERFAMILY SSF52540 69 327 6.52E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 116 319 6.6E-17 T 16-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 SUPERFAMILY SSF50249 18 83 8.05E-8 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 Pfam PF07497 Rho termination factor, RNA-binding domain 19 83 1.6E-9 T 16-09-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 PANTHER PTHR15184 72 372 2.9E-144 T 16-09-2016 Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 SMART SM00382 126 311 5.4E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS03115 0dfc4297ab1865bb3832eb8ae39ea3ca 379 PANTHER PTHR15184:SF34 72 372 2.9E-144 T 16-09-2016 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 SUPERFAMILY SSF51230 569 642 4.45E-21 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 SMART SM00878 338 449 3.6E-47 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 5.9E-78 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 599 616 - T 16-09-2016 IPR001882 Biotin-binding site Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Pfam PF00364 Biotin-requiring enzyme 577 642 2.1E-18 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Gene3D G3DSA:3.30.1490.20 130 201 8.8E-25 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 SUPERFAMILY SSF52440 1 113 8.63E-48 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 SUPERFAMILY SSF51246 333 453 2.56E-32 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Gene3D G3DSA:3.40.50.20 1 129 4.9E-52 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Gene3D G3DSA:2.40.50.100 574 643 8.3E-25 T 16-09-2016 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Gene3D G3DSA:3.30.470.20 203 452 1.2E-94 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-44 T 16-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 Pfam PF02785 Biotin carboxylase C-terminal domain 338 449 7.6E-31 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 PANTHER PTHR18866:SF102 1 646 0.0 T 16-09-2016 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 PANTHER PTHR18866 1 646 0.0 T 16-09-2016 Spa2297_RS11760 79237d33dc6fa584a07309540b0059de 653 SUPERFAMILY SSF56059 83 348 4.07E-69 T 16-09-2016 Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PANTHER PTHR24322 7 124 1.3E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PANTHER PTHR24322 140 172 1.3E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 SUPERFAMILY SSF51735 3 230 2.32E-82 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 7.4E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 Gene3D G3DSA:3.40.50.720 3 230 3.7E-83 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 230 4.8E-94 T 16-09-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 3.3E-62 T 16-09-2016 Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 5.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 5.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 5.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07220 129805b953fd9e3f8cde51925dfb9a96 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 3.3E-9 T 16-09-2016 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 SUPERFAMILY SSF47413 27 76 1.96E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 Gene3D G3DSA:1.10.260.40 2 78 8.9E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 PANTHER PTHR35010:SF2 3 276 3.6E-83 T 16-09-2016 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 SMART SM00530 7 79 1.6E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 PANTHER PTHR35010 3 276 3.6E-83 T 16-09-2016 Spa2297_RS15670 527ae3c279cda5ca7cc924f008fb46a4 282 Pfam PF13560 Helix-turn-helix domain 3 82 6.5E-18 T 16-09-2016 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 Pfam PF00005 ABC transporter 21 175 9.9E-34 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 SUPERFAMILY SSF55021 254 333 7.21E-17 T 16-09-2016 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 SMART SM00382 30 241 2.2E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 SUPERFAMILY SSF52540 2 243 2.96E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 SMART SM00930 257 332 5.7E-19 T 16-09-2016 IPR018449 NIL domain Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 PANTHER PTHR24220 3 259 6.7E-134 T 16-09-2016 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 PANTHER PTHR24220:SF186 3 259 6.7E-134 T 16-09-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 Pfam PF09383 NIL domain 259 330 1.5E-16 T 16-09-2016 IPR018449 NIL domain Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 Gene3D G3DSA:3.40.50.300 2 245 8.1E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05975 fd34e92923b565c4f6bcaf7a3ae2588b 348 Gene3D G3DSA:3.30.70.260 252 333 1.2E-20 T 16-09-2016 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 Gene3D G3DSA:3.30.70.250 131 196 2.5E-22 T 16-09-2016 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 Pfam PF00698 Acyl transferase domain 5 289 3.4E-19 T 16-09-2016 IPR014043 Acyl transferase Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 Gene3D G3DSA:3.40.366.10 2 127 7.6E-53 T 16-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 Gene3D G3DSA:3.40.366.10 197 302 7.6E-53 T 16-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 313 1.1E-17 T 16-09-2016 IPR020801 Polyketide synthase, acyl transferase domain Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 SUPERFAMILY SSF55048 135 190 1.44E-10 T 16-09-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 SUPERFAMILY SSF52151 2 127 1.73E-68 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 SUPERFAMILY SSF52151 190 313 1.73E-68 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS10035 145871986b156f5273cb5343d1b825e8 317 PANTHER PTHR10982 3 310 1.6E-87 T 16-09-2016 Spa2297_RS25655 e8aa1b381383460a703d4be276cc8264 422 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 294 301 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS25655 e8aa1b381383460a703d4be276cc8264 422 Gene3D G3DSA:3.30.470.20 114 330 7.4E-21 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS25655 e8aa1b381383460a703d4be276cc8264 422 SUPERFAMILY SSF56059 118 328 1.94E-25 T 16-09-2016 Spa2297_RS25655 e8aa1b381383460a703d4be276cc8264 422 Pfam PF02655 ATP-grasp domain 144 303 3.8E-9 T 16-09-2016 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 PANTHER PTHR22604:SF2 297 457 1.2E-164 T 16-09-2016 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 PANTHER PTHR22604:SF2 19 278 1.2E-164 T 16-09-2016 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 SUPERFAMILY SSF51735 51 219 6.78E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 PANTHER PTHR22604 297 457 1.2E-164 T 16-09-2016 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 PANTHER PTHR22604 19 278 1.2E-164 T 16-09-2016 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 60 184 2.6E-14 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS30965 ccfee68805e8afa1e096b6b85f69a7e3 473 Gene3D G3DSA:3.40.50.720 59 244 4.8E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Pfam PF13412 Winged helix-turn-helix DNA-binding 31 61 2.0E-5 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 ProSitePatterns PS01125 ROK family signature. 269 296 - T 16-09-2016 IPR000600 ROK family Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Gene3D G3DSA:3.30.420.40 275 318 7.1E-20 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 PANTHER PTHR18964:SF124 175 354 2.3E-74 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Gene3D G3DSA:3.30.420.40 328 407 7.2E-5 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Gene3D G3DSA:1.10.10.10 13 82 3.2E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 SUPERFAMILY SSF53067 86 137 3.31E-32 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 SUPERFAMILY SSF53067 194 408 3.31E-32 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Pfam PF00480 ROK family 193 318 2.9E-28 T 16-09-2016 IPR000600 ROK family Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 SUPERFAMILY SSF46785 13 78 2.58E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 PANTHER PTHR18964:SF124 64 145 2.3E-74 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 PANTHER PTHR18964 175 354 2.3E-74 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 PANTHER PTHR18964 64 145 2.3E-74 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Gene3D G3DSA:3.30.420.40 83 145 9.1E-52 T 16-09-2016 Spa2297_RS12200 df4378005144a20f7b8dad674ebec6ef 417 Gene3D G3DSA:3.30.420.40 192 274 9.1E-52 T 16-09-2016 Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 PANTHER PTHR19836 12 61 1.2E-33 T 16-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 SUPERFAMILY SSF57716 4 61 1.43E-21 T 16-09-2016 Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 16-09-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.974 T 16-09-2016 IPR023053 Ribosomal protein S14, type Z Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.4E-24 T 16-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19860 ce03bffac57297568d270b47503b5b39 61 Gene3D G3DSA:4.10.830.10 1 61 7.7E-28 T 16-09-2016 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 49 230 8.6E-45 T 16-09-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 Pfam PF01171 PP-loop family 49 227 5.0E-39 T 16-09-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 SUPERFAMILY SSF82829 239 343 1.67E-15 T 16-09-2016 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 SUPERFAMILY SSF52402 49 259 1.31E-46 T 16-09-2016 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 PANTHER PTHR11807 49 320 2.7E-50 T 16-09-2016 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 Pfam PF09179 TilS substrate binding domain 276 343 1.6E-10 T 16-09-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 Gene3D G3DSA:3.40.50.620 49 211 9.8E-12 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 PANTHER PTHR11807:SF2 49 320 2.7E-50 T 16-09-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spa2297_RS18170 bbcad36b4caf05905c24c70ee2cac3cf 348 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 18 337 20.541 T 16-09-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 Gene3D G3DSA:3.20.20.80 246 601 6.0E-66 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 SUPERFAMILY SSF51011 612 674 7.92E-7 T 16-09-2016 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 PANTHER PTHR10357:SF137 53 179 0.0 T 16-09-2016 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 PANTHER PTHR10357:SF137 212 698 0.0 T 16-09-2016 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 SUPERFAMILY SSF51445 246 603 1.06E-81 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 50 696 47.422 T 16-09-2016 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 Pfam PF11896 Domain of unknown function (DUF3416) 52 239 3.1E-59 T 16-09-2016 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 SMART SM00642 245 596 1.1E-4 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 Gene3D G3DSA:2.60.40.1180 607 684 7.0E-13 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 PANTHER PTHR10357 53 179 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23015 3eab4b18e038468e39aba964369542b7 708 PANTHER PTHR10357 212 698 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 PANTHER PTHR30204 124 246 2.7E-13 T 16-09-2016 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 Pfam PF00376 MerR family regulatory protein 15 49 1.1E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 Gene3D G3DSA:1.10.1660.10 134 245 3.1E-21 T 16-09-2016 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 Gene3D G3DSA:1.10.1660.10 15 117 5.1E-12 T 16-09-2016 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 SMART SM00422 11 64 0.02 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 SMART SM00422 134 201 1.3E-4 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 Pfam PF13411 MerR HTH family regulatory protein 134 200 8.2E-14 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 SUPERFAMILY SSF46955 15 115 6.87E-10 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS23190 492799d95ed22deb1a102d25bc9b699b 251 SUPERFAMILY SSF46955 134 243 9.16E-17 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 SUPERFAMILY SSF51735 3 166 2.55E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 SUPERFAMILY SSF55347 152 313 5.73E-62 T 16-09-2016 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 SMART SM00846 2 152 1.4E-83 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PIRSF PIRSF000149 1 332 2.2E-123 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PANTHER PTHR10836:SF50 1 332 5.7E-191 T 16-09-2016 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 9.1E-33 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 9.1E-33 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 9.1E-33 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 9.1E-33 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 9.1E-33 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 Gene3D G3DSA:3.40.50.720 1 160 1.9E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 16-09-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 4.5E-59 T 16-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 PANTHER PTHR10836 1 332 5.7E-191 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 1.9E-124 T 16-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 2.3E-54 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS01190 7586ad6417f2fd345a0e64fff80c0b53 332 Gene3D G3DSA:3.30.360.10 161 314 2.3E-64 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 627 4.1E-288 T 16-09-2016 IPR006298 GTP-binding protein TypA GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Gene3D G3DSA:2.40.30.10 222 319 1.3E-30 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 SUPERFAMILY SSF52540 4 221 5.66E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Gene3D G3DSA:3.30.70.240 431 508 7.5E-30 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 SUPERFAMILY SSF54980 427 541 1.25E-26 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 SUPERFAMILY SSF50447 199 316 2.5E-30 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PANTHER PTHR23115:SF14 200 630 1.8E-254 T 16-09-2016 IPR006298 GTP-binding protein TypA GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Pfam PF00679 Elongation factor G C-terminus 426 505 7.6E-20 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Gene3D G3DSA:3.40.50.300 3 221 2.1E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PANTHER PTHR23115 1 180 1.8E-254 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 SUPERFAMILY SSF54980 320 416 1.39E-9 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Pfam PF00009 Elongation factor Tu GTP binding domain 6 211 2.2E-51 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Gene3D G3DSA:2.40.50.250 511 605 1.2E-37 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PRINTS PR00315 GTP-binding elongation factor signature 81 91 4.0E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PRINTS PR00315 GTP-binding elongation factor signature 133 142 4.0E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PRINTS PR00315 GTP-binding elongation factor signature 55 63 4.0E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PRINTS PR00315 GTP-binding elongation factor signature 97 108 4.0E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.0E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Gene3D G3DSA:3.30.70.870 320 430 1.4E-33 T 16-09-2016 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 Pfam PF03144 Elongation factor Tu domain 2 235 305 9.7E-11 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PANTHER PTHR23115:SF14 1 180 1.8E-254 T 16-09-2016 IPR006298 GTP-binding protein TypA GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 159 1.4E-22 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS21555 06c367cae563e4943fd7305968f256a7 635 PANTHER PTHR23115 200 630 1.8E-254 T 16-09-2016 Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 PIRSF PIRSF018005 2 320 3.4E-139 T 16-09-2016 IPR017804 Methyltransferase EgtD-like Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 Gene3D G3DSA:3.40.50.150 52 243 1.1E-6 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 190 314 6.8E-41 T 16-09-2016 IPR019257 Histidine-specific methyltransferase, SAM-dependent Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 SUPERFAMILY SSF53335 54 204 2.44E-12 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 SUPERFAMILY SSF53335 254 308 2.44E-12 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 PANTHER PTHR30468 17 317 6.4E-84 T 16-09-2016 Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 316 1.6E-116 T 16-09-2016 IPR017804 Methyltransferase EgtD-like Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 319 56.375 T 16-09-2016 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550|UniPathway: UPA01014 Spa2297_RS29070 ab9642c307bdea0905b7e9161100c266 320 PANTHER PTHR30468:SF6 17 317 6.4E-84 T 16-09-2016 Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 SMART SM00382 209 407 0.0086 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 Pfam PF00437 Type II/IV secretion system protein 86 362 1.5E-89 T 16-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 Gene3D G3DSA:3.40.50.300 184 418 8.4E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 PANTHER PTHR30258 24 372 8.9E-124 T 16-09-2016 Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 Gene3D G3DSA:3.30.450.90 83 180 1.5E-37 T 16-09-2016 Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 PANTHER PTHR30258:SF3 24 372 8.9E-124 T 16-09-2016 Spa2297_RS21180 2add9e3ac58bef0632c41933ef4d9afa 445 SUPERFAMILY SSF52540 69 391 1.53E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 Gene3D G3DSA:2.40.110.10 180 272 1.0E-20 T 16-09-2016 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 441 7.8E-29 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 SUPERFAMILY SSF47203 290 444 1.93E-39 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 Gene3D G3DSA:1.20.140.10 273 444 4.1E-39 T 16-09-2016 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 275 6.1E-17 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 PANTHER PTHR10909 57 461 3.7E-200 T 16-09-2016 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 PANTHER PTHR10909:SF289 57 461 3.7E-200 T 16-09-2016 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 400 419 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS25805 1fe8fdfebe5e57599d9d466f011a1f62 547 SUPERFAMILY SSF56645 59 282 3.1E-34 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 Gene3D G3DSA:3.30.200.20 16 103 2.4E-26 T 16-09-2016 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 PANTHER PTHR24362 18 302 1.7E-101 T 16-09-2016 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 SUPERFAMILY SSF56112 16 344 5.13E-74 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 Gene3D G3DSA:1.10.510.10 116 315 1.1E-47 T 16-09-2016 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 PANTHER PTHR24362:SF160 18 302 1.7E-101 T 16-09-2016 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 SMART SM00220 20 287 5.3E-66 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 SMART SM00740 478 546 5.7E-14 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 Pfam PF00069 Protein kinase domain 20 284 2.2E-49 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16865 2691c9a3b8c817b2c41f10917ff97c41 552 Pfam PF03793 PASTA domain 482 546 1.9E-10 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 Gene3D G3DSA:3.40.50.2300 9 129 3.4E-41 T 16-09-2016 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 Gene3D G3DSA:1.10.10.10 130 230 5.8E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 SMART SM00448 8 118 8.0E-43 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 SMART SM00862 151 227 1.0E-22 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 PANTHER PTHR26402:SF50 8 230 1.1E-100 T 16-09-2016 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 SUPERFAMILY SSF52172 9 178 2.64E-41 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 Pfam PF00072 Response regulator receiver domain 11 118 4.7E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 PANTHER PTHR26402 8 230 1.1E-100 T 16-09-2016 Spa2297_RS20770 fc66c4adbf7dc42607b61a53a2843e6e 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 1.2E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS17455 42c8e51f364212cbe325903769f3358f 1048 Pfam PF13860 FlgD Ig-like domain 712 770 8.8E-9 T 16-09-2016 IPR025965 FlgD Ig-like domain Spa2297_RS17455 42c8e51f364212cbe325903769f3358f 1048 SUPERFAMILY SSF69318 783 928 7.72E-12 T 16-09-2016 Spa2297_RS17455 42c8e51f364212cbe325903769f3358f 1048 SUPERFAMILY SSF69318 886 1044 1.01E-16 T 16-09-2016 Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 SUPERFAMILY SSF53335 11 241 4.76E-37 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 Gene3D G3DSA:3.40.50.150 12 154 2.4E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 Gene3D G3DSA:3.40.50.150 198 225 2.4E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 PANTHER PTHR10108 193 224 2.5E-19 T 16-09-2016 Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 PANTHER PTHR10108 1 157 2.5E-19 T 16-09-2016 Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 Pfam PF13649 Methyltransferase domain 40 132 6.3E-16 T 16-09-2016 Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 PANTHER PTHR10108:SF779 193 224 2.5E-19 T 16-09-2016 Spa2297_RS30675 e6e092acbea4db0714faaa22d3fffdc7 241 PANTHER PTHR10108:SF779 1 157 2.5E-19 T 16-09-2016 Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 Pfam PF11706 CGNR zinc finger 125 167 2.8E-18 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 PANTHER PTHR35525 4 168 1.0E-64 T 16-09-2016 Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 Pfam PF07336 Putative stress-induced transcription regulator 13 120 4.1E-5 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 Gene3D G3DSA:1.10.3300.10 8 168 1.6E-36 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 PANTHER PTHR35525:SF2 4 168 1.0E-64 T 16-09-2016 Spa2297_RS13230 18411b3925e1d8cd1a1207a487a20238 169 SUPERFAMILY SSF160904 1 167 1.2E-37 T 16-09-2016 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PANTHER PTHR11019 27 140 7.0E-45 T 16-09-2016 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 SMART SM00342 221 304 1.7E-31 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 209 250 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 SUPERFAMILY SSF46689 257 309 9.86E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 288 3.8E-6 T 16-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 304 3.8E-6 T 16-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PANTHER PTHR11019 187 312 7.0E-45 T 16-09-2016 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PANTHER PTHR11019:SF77 187 312 7.0E-45 T 16-09-2016 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 Pfam PF12833 Helix-turn-helix domain 227 305 1.6E-22 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 SUPERFAMILY SSF46689 204 254 3.05E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 300 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 Gene3D G3DSA:1.10.10.60 259 310 3.8E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 SUPERFAMILY SSF51215 10 84 1.96E-9 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 Gene3D G3DSA:2.60.120.10 16 87 2.6E-8 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 PANTHER PTHR11019:SF77 27 140 7.0E-45 T 16-09-2016 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 Gene3D G3DSA:1.10.10.60 201 258 6.9E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23920 312145d5200c37cabec8cc4a601a1854 318 Pfam PF12852 Cupin 4 190 6.7E-33 T 16-09-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 84 303 2.8E-32 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 PANTHER PTHR30385 11 308 1.8E-152 T 16-09-2016 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 81 304 4.7E-93 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Gene3D G3DSA:1.10.601.10 68 154 1.4E-25 T 16-09-2016 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 111 124 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 SUPERFAMILY SSF88946 50 156 1.04E-31 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Gene3D G3DSA:1.10.10.10 155 210 1.3E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 SUPERFAMILY SSF88659 223 304 1.87E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Gene3D G3DSA:1.10.10.10 250 304 4.3E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Pfam PF04542 Sigma-70 region 2 87 156 3.7E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Pfam PF04539 Sigma-70 region 3 167 233 2.3E-15 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 SUPERFAMILY SSF88659 160 234 4.8E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 PRINTS PR00046 Major sigma-70 factor signature 274 289 3.2E-10 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 PRINTS PR00046 Major sigma-70 factor signature 257 269 3.2E-10 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 PRINTS PR00046 Major sigma-70 factor signature 111 124 3.2E-10 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 Pfam PF04545 Sigma-70, region 4 254 302 1.1E-17 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13310 14350545f3467e9078764f84b57fd891 308 PANTHER PTHR30385:SF4 11 308 1.8E-152 T 16-09-2016 Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 Gene3D G3DSA:3.40.50.2300 45 158 3.7E-23 T 16-09-2016 Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 Gene3D G3DSA:3.40.50.2300 159 345 1.4E-37 T 16-09-2016 Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 PANTHER PTHR30036 2 358 3.0E-177 T 16-09-2016 Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 PANTHER PTHR30036:SF1 2 358 3.0E-177 T 16-09-2016 Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 SUPERFAMILY SSF53822 44 344 2.02E-58 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS17500 ed65994c05b31531f4cddca6ce242172 372 Pfam PF13407 Periplasmic binding protein domain 46 307 2.1E-63 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 SUPERFAMILY SSF51395 4 348 3.05E-99 T 16-09-2016 Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 Gene3D G3DSA:3.20.20.70 5 355 1.6E-135 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 253 259 - T 16-09-2016 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 PIRSF PIRSF000138 3 354 4.8E-125 T 16-09-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 Pfam PF01070 FMN-dependent dehydrogenase 12 353 2.4E-128 T 16-09-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 Spa2297_RS26645 53ab0239f61e17b27720724f0eabdd25 358 PANTHER PTHR10578 5 348 7.0E-154 T 16-09-2016 Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 SUPERFAMILY SSF52833 2 177 2.24E-53 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 PANTHER PTHR10681 1 184 3.9E-103 T 16-09-2016 Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 Pfam PF00578 AhpC/TSA family 4 136 2.2E-33 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 PIRSF PIRSF000239 1 184 1.2E-49 T 16-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 PANTHER PTHR10681:SF87 1 184 3.9E-103 T 16-09-2016 Spa2297_RS21300 fd76f9140b1a97e037f5ea33f6fd01c5 184 Gene3D G3DSA:3.40.30.10 2 178 8.0E-61 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 Gene3D G3DSA:3.90.1300.10 2 484 1.5E-175 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 SUPERFAMILY SSF75304 1 481 5.1E-162 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 ProSitePatterns PS00571 Amidases signature. 153 184 - T 16-09-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 482 4.2E-187 T 16-09-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 PANTHER PTHR11895 1 489 1.4E-218 T 16-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 PANTHER PTHR11895:SF75 1 489 1.4E-218 T 16-09-2016 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 Pfam PF01425 Amidase 26 471 3.6E-158 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23265 b0f2bb584324ae54f7d2132ce4ac91be 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 90.083 T 16-09-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 3.1E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 PANTHER PTHR30055:SF54 1 177 5.5E-62 T 16-09-2016 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 PANTHER PTHR30055 1 177 5.5E-62 T 16-09-2016 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 Gene3D G3DSA:1.10.357.10 59 195 1.1E-14 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 Gene3D G3DSA:1.10.10.60 6 58 5.7E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22750 92445d985fb3e53d9cc6ba215f9aecb5 213 SUPERFAMILY SSF46689 5 78 3.24E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01670 0337446e4f781b937f529582a6079037 263 SUPERFAMILY SSF53335 16 250 1.07E-40 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01670 0337446e4f781b937f529582a6079037 263 PIRSF PIRSF017393 1 263 1.7E-91 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS01670 0337446e4f781b937f529582a6079037 263 Gene3D G3DSA:3.40.50.150 2 262 4.1E-104 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01670 0337446e4f781b937f529582a6079037 263 Pfam PF04672 S-adenosyl methyltransferase 5 262 4.0E-113 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 SUPERFAMILY SSF46955 36 99 4.49E-12 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 Gene3D G3DSA:1.10.1660.10 36 99 1.4E-16 T 16-09-2016 Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 Pfam PF00376 MerR family regulatory protein 22 63 2.5E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 SMART SM00422 21 95 2.3E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 PANTHER PTHR30204:SF9 13 102 5.4E-43 T 16-09-2016 Spa2297_RS05070 fcbebf77746541dcdb64513598a9bff5 245 PANTHER PTHR30204 13 102 5.4E-43 T 16-09-2016 Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 Pfam PF00005 ABC transporter 20 165 4.2E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 Gene3D G3DSA:3.40.50.300 2 228 4.4E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 SUPERFAMILY SSF52540 4 226 2.66E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 PANTHER PTHR24220:SF331 6 266 1.5E-143 T 16-09-2016 Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 PANTHER PTHR24220 6 266 1.5E-143 T 16-09-2016 Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 SMART SM00382 28 222 3.8E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15435 aa98b019cbb415b0f5ba346aa01dd84e 288 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS25040 c76c69ac4bcaba00e3c6d56a8755f66e 249 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 207 1.6E-50 T 16-09-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 Spa2297_RS25040 c76c69ac4bcaba00e3c6d56a8755f66e 249 PANTHER PTHR34857 2 248 9.9E-71 T 16-09-2016 Spa2297_RS25040 c76c69ac4bcaba00e3c6d56a8755f66e 249 PANTHER PTHR34857:SF1 2 248 9.9E-71 T 16-09-2016 Spa2297_RS25040 c76c69ac4bcaba00e3c6d56a8755f66e 249 Pfam PF02361 Cobalt transport protein 11 213 1.7E-50 T 16-09-2016 IPR003339 ABC/ECF transporter, transmembrane component Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 SUPERFAMILY SSF52402 5 140 1.67E-28 T 16-09-2016 Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 PANTHER PTHR31964 1 156 3.1E-45 T 16-09-2016 Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 Gene3D G3DSA:3.40.50.620 1 138 5.8E-32 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 Gene3D G3DSA:3.40.50.620 157 298 9.7E-24 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 SUPERFAMILY SSF52402 161 298 2.43E-20 T 16-09-2016 Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 PRINTS PR01438 Universal stress protein signature 2 20 8.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 PRINTS PR01438 Universal stress protein signature 98 110 8.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 PRINTS PR01438 Universal stress protein signature 116 138 8.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 PANTHER PTHR31964:SF42 1 156 3.1E-45 T 16-09-2016 Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 Pfam PF00582 Universal stress protein family 161 298 4.2E-18 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS03950 5f9138c23f74b152017fe622d2799148 301 Pfam PF00582 Universal stress protein family 1 138 2.7E-26 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 SUPERFAMILY SSF51905 4 337 1.3E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 Gene3D G3DSA:3.50.50.60 8 147 1.5E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 Gene3D G3DSA:3.30.390.30 361 476 2.9E-26 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 SUPERFAMILY SSF55424 358 476 3.78E-27 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.6E-16 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.6E-16 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.6E-16 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.6E-16 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 358 379 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 439 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 446 466 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 9.4E-49 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PIRSF PIRSF000350 1 474 1.8E-72 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PANTHER PTHR22912:SF166 1 475 1.3E-241 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 362 468 6.5E-22 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 PANTHER PTHR22912 1 475 1.3E-241 T 16-09-2016 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 323 5.8E-47 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29175 194cd49f4299ffef1e121b8428c0e3ef 478 Gene3D G3DSA:3.50.50.60 148 336 2.9E-34 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07965 236c2c8e59a64f905721dc6bd005fd01 302 SUPERFAMILY SSF110581 3 300 1.44E-103 T 16-09-2016 Spa2297_RS07965 236c2c8e59a64f905721dc6bd005fd01 302 Pfam PF04227 Indigoidine synthase A like protein 8 297 8.0E-116 T 16-09-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spa2297_RS07965 236c2c8e59a64f905721dc6bd005fd01 302 PANTHER PTHR10584:SF1 2 217 3.3E-72 T 16-09-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spa2297_RS07965 236c2c8e59a64f905721dc6bd005fd01 302 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 7 301 40.843 T 16-09-2016 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spa2297_RS07965 236c2c8e59a64f905721dc6bd005fd01 302 PANTHER PTHR10584 2 217 3.3E-72 T 16-09-2016 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 198 1.3E-24 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 Gene3D G3DSA:1.10.10.10 145 202 7.3E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 PANTHER PTHR30173:SF2 19 202 1.8E-87 T 16-09-2016 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 PANTHER PTHR30173 19 202 1.8E-87 T 16-09-2016 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 Pfam PF04542 Sigma-70 region 2 48 113 1.8E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 SUPERFAMILY SSF88946 27 129 8.24E-24 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 SUPERFAMILY SSF88659 144 200 3.49E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 Pfam PF08281 Sigma-70, region 4 145 196 2.2E-16 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 70 101 - T 16-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00900 0547606bc35bc2b6e98f693ef508acff 222 Gene3D G3DSA:1.10.1740.10 27 132 3.8E-25 T 16-09-2016 Spa2297_RS15020 a4bdcdc4359f3ca020e87eda70f74fc4 639 Gene3D G3DSA:3.55.50.10 109 179 2.4E-5 T 16-09-2016 Spa2297_RS15020 a4bdcdc4359f3ca020e87eda70f74fc4 639 Gene3D G3DSA:2.40.50.230 385 455 2.0E-14 T 16-09-2016 IPR006531 Gp5 N-terminal Spa2297_RS15020 a4bdcdc4359f3ca020e87eda70f74fc4 639 SUPERFAMILY SSF69255 380 456 6.02E-13 T 16-09-2016 Spa2297_RS15020 a4bdcdc4359f3ca020e87eda70f74fc4 639 Pfam PF05954 Phage late control gene D protein (GPD) 80 343 4.8E-13 T 16-09-2016 Spa2297_RS15020 a4bdcdc4359f3ca020e87eda70f74fc4 639 SUPERFAMILY SSF69279 11 184 5.53E-19 T 16-09-2016 Spa2297_RS27990 cb7fb87df87d706cd1677c1a2f57d63d 353 PANTHER PTHR32010 30 351 3.0E-64 T 16-09-2016 Spa2297_RS27990 cb7fb87df87d706cd1677c1a2f57d63d 353 SUPERFAMILY SSF110296 39 320 4.45E-38 T 16-09-2016 Spa2297_RS27990 cb7fb87df87d706cd1677c1a2f57d63d 353 Gene3D G3DSA:2.130.10.140 33 329 2.8E-38 T 16-09-2016 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 Gene3D G3DSA:1.10.10.60 27 71 3.0E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 PANTHER PTHR30328 7 193 5.8E-98 T 16-09-2016 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 Gene3D G3DSA:1.10.357.10 72 209 2.9E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 PANTHER PTHR30328:SF21 7 193 5.8E-98 T 16-09-2016 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 SUPERFAMILY SSF48498 91 208 6.43E-20 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 77 2.0E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 91 199 1.8E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 SUPERFAMILY SSF46689 27 81 3.24E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS12925 b084bde0c68b76f9922c9a95827ec815 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 45 76 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS24335 0f00fdbd44556b231dc6eb6c715537d0 257 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 68 237 7.8E-37 T 16-09-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 Spa2297_RS24335 0f00fdbd44556b231dc6eb6c715537d0 257 PANTHER PTHR14269 14 234 1.9E-43 T 16-09-2016 Spa2297_RS24335 0f00fdbd44556b231dc6eb6c715537d0 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 116 138 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS24335 0f00fdbd44556b231dc6eb6c715537d0 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 68 138 1.1E-15 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS10570 74a2ff954a047ba876f536f5850458b2 256 Pfam PF00005 ABC transporter 22 169 5.4E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10570 74a2ff954a047ba876f536f5850458b2 256 PANTHER PTHR24220 8 226 5.7E-66 T 16-09-2016 Spa2297_RS10570 74a2ff954a047ba876f536f5850458b2 256 Gene3D G3DSA:3.40.50.300 3 230 1.6E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10570 74a2ff954a047ba876f536f5850458b2 256 SMART SM00382 31 225 5.4E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10570 74a2ff954a047ba876f536f5850458b2 256 SUPERFAMILY SSF52540 4 234 1.49E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 PANTHER PTHR10907:SF33 65 210 2.8E-27 T 16-09-2016 Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 SUPERFAMILY SSF53474 257 348 1.99E-33 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 SUPERFAMILY SSF53474 65 211 1.99E-33 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 Gene3D G3DSA:3.40.50.1820 64 357 6.9E-47 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 Pfam PF00756 Putative esterase 70 351 2.4E-31 T 16-09-2016 IPR000801 Putative esterase Spa2297_RS25200 c3d23093ee8dbf69de741eb7ec9eb905 365 PANTHER PTHR10907 65 210 2.8E-27 T 16-09-2016 Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 SUPERFAMILY SSF51556 78 361 3.4E-52 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 PANTHER PTHR32027:SF0 5 419 1.3E-112 T 16-09-2016 Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 Gene3D G3DSA:2.30.40.10 23 85 6.2E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 SUPERFAMILY SSF51338 23 91 4.32E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 Gene3D G3DSA:3.20.20.140 97 352 2.4E-58 T 16-09-2016 Spa2297_RS19545 d6d53e77568cb2dd6418c418d8b3c1e8 423 PANTHER PTHR32027 5 419 1.3E-112 T 16-09-2016 Spa2297_RS15090 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.4E-15 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS15090 a0bfa7561af2171531debebbc32dfcd8 160 PANTHER PTHR38447 1 160 2.6E-70 T 16-09-2016 Spa2297_RS15090 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS15090 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Gene3D G3DSA:3.30.230.10 8 211 1.3E-72 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 16-09-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Pfam PF10509 Galactokinase galactose-binding signature 11 59 3.6E-22 T 16-09-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00473 Galactokinase signature 113 131 5.2E-23 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00473 Galactokinase signature 269 283 5.2E-23 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00473 Galactokinase signature 29 47 5.2E-23 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00473 Galactokinase signature 93 104 5.2E-23 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 SUPERFAMILY SSF55060 208 385 3.24E-46 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Gene3D G3DSA:3.30.70.890 212 384 7.9E-52 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 ProSitePatterns PS00106 Galactokinase signature. 29 40 - T 16-09-2016 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PANTHER PTHR10457 3 385 8.4E-123 T 16-09-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Pfam PF08544 GHMP kinases C terminal 287 361 9.2E-10 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Pfam PF00288 GHMP kinases N terminal domain 115 181 1.2E-15 T 16-09-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 TIGRFAM TIGR00131 gal_kin: galactokinase 9 363 1.3E-86 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 Hamap MF_00246 Galactokinase [galK]. 27 385 42.17 T 16-09-2016 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00959 Mevalonate kinase family signature 27 51 3.3E-39 T 16-09-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00959 Mevalonate kinase family signature 163 182 3.3E-39 T 16-09-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00959 Mevalonate kinase family signature 120 142 3.3E-39 T 16-09-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PRINTS PR00959 Mevalonate kinase family signature 332 349 3.3E-39 T 16-09-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 SUPERFAMILY SSF54211 7 203 7.29E-61 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PIRSF PIRSF000530 2 387 2.0E-126 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS13645 3b03c65dd1b825bdd6428f296cf685ea 387 PANTHER PTHR10457:SF6 3 385 8.4E-123 T 16-09-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 SUPERFAMILY SSF56645 9 253 1.31E-71 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 PANTHER PTHR10909:SF10 10 398 1.1E-159 T 16-09-2016 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 230 4.4E-20 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Gene3D G3DSA:1.10.540.10 9 123 3.1E-38 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Gene3D G3DSA:2.40.110.10 125 231 1.8E-33 T 16-09-2016 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Gene3D G3DSA:1.20.140.10 232 398 4.6E-60 T 16-09-2016 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 6.5E-32 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 PANTHER PTHR10909 10 398 1.1E-159 T 16-09-2016 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 SUPERFAMILY SSF47203 245 397 3.7E-53 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS26915 fafca842060b2e15bae8dd001ec27c51 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 394 1.2E-46 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PIRSF PIRSF001467 1 165 1.3E-78 T 16-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 139 9.2E-39 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 53 65 9.2E-39 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 96 111 9.2E-39 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 24 39 9.2E-39 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 111 123 9.2E-39 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 SUPERFAMILY SSF50891 2 163 1.61E-70 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 48 65 - T 16-09-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PANTHER PTHR11071 1 165 3.0E-122 T 16-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 160 2.8E-48 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 PANTHER PTHR11071:SF266 1 165 3.0E-122 T 16-09-2016 Spa2297_RS01195 1eec2c3a60bf5fa3ec036c99eb2f992b 165 Gene3D G3DSA:2.40.100.10 1 163 1.7E-74 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 Gene3D G3DSA:3.20.20.450 475 720 1.9E-91 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 PANTHER PTHR33121:SF13 434 744 3.0E-80 T 16-09-2016 Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 PANTHER PTHR33121 434 744 3.0E-80 T 16-09-2016 Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 SUPERFAMILY SSF55073 304 455 2.28E-44 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 Gene3D G3DSA:3.30.70.270 301 462 1.6E-50 T 16-09-2016 Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 Pfam PF00990 Diguanylate cyclase, GGDEF domain 301 453 9.8E-41 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 SMART SM00052 469 713 2.8E-104 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 SUPERFAMILY SSF141868 475 721 2.88E-83 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 SMART SM00267 293 459 7.2E-47 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 299 453 1.7E-34 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23255 a448f79b9e84c169bf392d5715b17044 745 Pfam PF00563 EAL domain 476 706 2.0E-70 T 16-09-2016 IPR001633 EAL domain Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PANTHER PTHR11817 1 474 4.0E-218 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 SUPERFAMILY SSF51621 155 338 1.36E-94 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 SUPERFAMILY SSF51621 1 74 1.36E-94 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 9.5E-164 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.0E-61 T 16-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 2.9E-122 T 16-09-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 16-09-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Gene3D G3DSA:2.40.33.10 73 167 1.2E-28 T 16-09-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 SUPERFAMILY SSF50800 70 165 1.92E-26 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Gene3D G3DSA:3.20.20.60 2 72 4.7E-101 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Gene3D G3DSA:3.20.20.60 168 324 4.7E-101 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 SUPERFAMILY SSF52935 321 472 5.89E-39 T 16-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Gene3D G3DSA:3.40.1380.20 325 471 2.5E-43 T 16-09-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08195 afa12f4486e4c150c2b4609860a9193a 476 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 1.1E-28 T 16-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 Gene3D G3DSA:1.10.10.10 9 76 4.7E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 1.2E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 Gene3D G3DSA:3.40.640.10 122 321 4.7E-32 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 Gene3D G3DSA:3.90.1150.10 322 412 7.3E-6 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 SUPERFAMILY SSF46785 10 78 4.09E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 SUPERFAMILY SSF53383 65 425 1.58E-54 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 PANTHER PTHR11751 72 412 3.5E-34 T 16-09-2016 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 SMART SM00345 10 69 9.8E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04975 45779563c1f69acc9cfd4f84ddc634ff 440 Pfam PF00155 Aminotransferase class I and II 124 423 9.0E-15 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 PANTHER PTHR24362 229 426 3.4E-20 T 16-09-2016 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 SMART SM00220 230 526 3.7E-5 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 SMART SM01260 529 852 3.5E-5 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 SUPERFAMILY SSF56112 230 415 1.05E-22 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 Pfam PF00069 Protein kinase domain 241 431 6.2E-11 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 Gene3D G3DSA:1.10.510.10 366 432 1.4E-8 T 16-09-2016 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 SUPERFAMILY SSF158745 534 848 2.09E-24 T 16-09-2016 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 Gene3D G3DSA:3.30.200.20 230 365 1.2E-10 T 16-09-2016 Spa2297_RS27795 50a8e01555e43cbd6e02ad4c1a55154d 869 PANTHER PTHR24362:SF160 229 426 3.4E-20 T 16-09-2016 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 PANTHER PTHR32060 41 358 3.3E-87 T 16-09-2016 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 SUPERFAMILY SSF50156 74 184 1.71E-15 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 SMART SM00245 166 350 1.3E-41 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 Gene3D G3DSA:2.30.42.10 89 174 4.0E-18 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 Pfam PF03572 Peptidase family S41 194 349 3.5E-40 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 Gene3D G3DSA:3.90.226.10 175 353 1.5E-45 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 90 148 2.5E-8 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 SMART SM00228 89 166 8.8E-8 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 SUPERFAMILY SSF52096 185 353 1.99E-45 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS12825 fb3d70d3cb5b2bb4c205db72ffc635c7 371 SUPERFAMILY SSF52096 50 108 1.99E-45 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS28510 832b7a7485e7d37e6d1f4ff90801e53c 386 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 50 282 4.8E-38 T 16-09-2016 IPR008775 Phytanoyl-CoA dioxygenase Spa2297_RS28510 832b7a7485e7d37e6d1f4ff90801e53c 386 SUPERFAMILY SSF51197 73 354 6.41E-50 T 16-09-2016 Spa2297_RS28510 832b7a7485e7d37e6d1f4ff90801e53c 386 PANTHER PTHR21308 5 368 2.3E-79 T 16-09-2016 Spa2297_RS28510 832b7a7485e7d37e6d1f4ff90801e53c 386 PANTHER PTHR21308:SF1 5 368 2.3E-79 T 16-09-2016 Spa2297_RS28510 832b7a7485e7d37e6d1f4ff90801e53c 386 Gene3D G3DSA:2.60.120.620 73 283 2.0E-19 T 16-09-2016 Spa2297_RS30970 48d7514b8130ec80012d4662a9536e79 361 Gene3D G3DSA:3.40.630.30 159 295 2.5E-4 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30970 48d7514b8130ec80012d4662a9536e79 361 Pfam PF13480 Acetyltransferase (GNAT) domain 160 300 2.1E-39 T 16-09-2016 Spa2297_RS30970 48d7514b8130ec80012d4662a9536e79 361 SUPERFAMILY SSF55729 163 311 4.98E-24 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 PANTHER PTHR10091:SF0 36 382 6.1E-162 T 16-09-2016 Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 SUPERFAMILY SSF74650 37 380 4.46E-116 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 PIRSF PIRSF005096 33 382 4.0E-130 T 16-09-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 PANTHER PTHR10091 36 382 6.1E-162 T 16-09-2016 Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 Gene3D G3DSA:2.70.98.10 39 381 5.5E-132 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS10135 85ef15ee7a4399b75308a8ba64bbdee7 382 Pfam PF01263 Aldose 1-epimerase 51 377 1.5E-92 T 16-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 SUPERFAMILY SSF46785 5 74 1.68E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 PANTHER PTHR11751 11 73 4.9E-17 T 16-09-2016 Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 PANTHER PTHR11751 93 115 4.9E-17 T 16-09-2016 Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 Gene3D G3DSA:1.20.120.530 86 220 4.7E-20 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 SMART SM00345 12 70 3.5E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 Gene3D G3DSA:1.10.10.10 5 70 1.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 SMART SM00895 99 223 1.5E-16 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 SUPERFAMILY SSF48008 96 224 1.52E-20 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 Pfam PF07729 FCD domain 100 219 6.2E-20 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS06545 e3e9da0ce5824c213aef2b87690e3912 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 70 2.9E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 PANTHER PTHR30289:SF0 3 179 4.2E-92 T 16-09-2016 Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 4.1E-39 T 16-09-2016 IPR008914 Phosphatidylethanolamine-binding protein Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 40 170 4.0E-43 T 16-09-2016 IPR005247 YbhB/YbcL Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 Gene3D G3DSA:3.90.280.10 19 174 1.8E-55 T 16-09-2016 IPR008914 Phosphatidylethanolamine-binding protein Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 PANTHER PTHR30289 3 179 4.2E-92 T 16-09-2016 Spa2297_RS07115 14a7eae92308215a0693218047d5a6f3 179 SUPERFAMILY SSF49777 20 175 5.1E-52 T 16-09-2016 IPR008914 Phosphatidylethanolamine-binding protein Spa2297_RS22660 272013b3c1375d04b20cabd4bba33e4f 433 PANTHER PTHR22926 2 252 4.5E-113 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS22660 272013b3c1375d04b20cabd4bba33e4f 433 PANTHER PTHR22926 276 391 4.5E-113 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS22660 272013b3c1375d04b20cabd4bba33e4f 433 PANTHER PTHR22926:SF3 2 252 4.5E-113 T 16-09-2016 Spa2297_RS22660 272013b3c1375d04b20cabd4bba33e4f 433 PANTHER PTHR22926:SF3 276 391 4.5E-113 T 16-09-2016 Spa2297_RS22660 272013b3c1375d04b20cabd4bba33e4f 433 Pfam PF00953 Glycosyl transferase family 4 83 242 2.4E-35 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 Pfam PF00582 Universal stress protein family 1 140 1.3E-18 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 Pfam PF00582 Universal stress protein family 149 288 7.2E-29 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 Gene3D G3DSA:3.40.50.620 1 141 8.5E-25 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PANTHER PTHR31964 1 85 1.8E-30 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PANTHER PTHR31964 234 302 1.8E-30 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PANTHER PTHR31964:SF42 1 85 1.8E-30 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PANTHER PTHR31964:SF42 234 302 1.8E-30 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 Gene3D G3DSA:3.40.50.620 145 288 4.4E-35 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 SUPERFAMILY SSF52402 148 292 9.21E-31 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 SUPERFAMILY SSF52402 3 142 6.53E-24 T 16-09-2016 Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PRINTS PR01438 Universal stress protein signature 146 164 5.6E-15 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PRINTS PR01438 Universal stress protein signature 266 288 5.6E-15 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS04000 489cea68c81fef6de7b1ec298cbb164d 302 PRINTS PR01438 Universal stress protein signature 248 260 5.6E-15 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SUPERFAMILY SSF55781 142 326 3.93E-56 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 648 764 9.8E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 PANTHER PTHR24423:SF518 115 762 1.2E-109 T 16-09-2016 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SUPERFAMILY SSF55874 594 762 5.24E-36 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SUPERFAMILY SSF47384 522 603 4.9E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Gene3D G3DSA:3.30.450.40 149 309 4.0E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SMART SM00388 537 605 2.3E-6 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Pfam PF00360 Phytochrome region 352 521 2.6E-27 T 16-09-2016 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Gene3D G3DSA:1.10.287.130 538 590 1.6E-4 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Pfam PF01590 GAF domain 163 326 3.3E-20 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Pfam PF00512 His Kinase A (phospho-acceptor) domain 539 603 2.9E-7 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Gene3D G3DSA:3.30.565.10 591 762 1.0E-36 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SMART SM00065 160 339 1.4E-10 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 750 763 9.6E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 706 9.6E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 726 744 9.6E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SUPERFAMILY SSF55781 352 522 9.51E-34 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 PANTHER PTHR24423 115 762 1.2E-109 T 16-09-2016 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 Pfam PF08446 PAS fold 26 132 9.8E-15 T 16-09-2016 IPR013654 PAS fold-2 GO:0006355 Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SMART SM00387 647 766 3.1E-31 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25940 ab0d83b7b9898bb3337191822d6f05f3 772 SUPERFAMILY SSF55785 18 133 2.62E-23 T 16-09-2016 IPR000014 PAS domain Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 PANTHER PTHR15238 7 53 4.6E-19 T 16-09-2016 Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 1.9E-19 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 16-09-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 13.166 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 SUPERFAMILY SSF57829 6 54 8.55E-15 T 16-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spa2297_RS30755 d1244e715fe5c12a43c80b683810b346 54 Pfam PF00471 Ribosomal protein L33 9 54 3.6E-14 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS15825 5c42abc30fb0ce8c13c6119ebad0f041 270 PANTHER PTHR30294 17 269 2.8E-85 T 16-09-2016 Spa2297_RS15825 5c42abc30fb0ce8c13c6119ebad0f041 270 PIRSF PIRSF006648 1 265 1.3E-15 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS15825 5c42abc30fb0ce8c13c6119ebad0f041 270 PANTHER PTHR30294:SF6 17 269 2.8E-85 T 16-09-2016 Spa2297_RS15825 5c42abc30fb0ce8c13c6119ebad0f041 270 Pfam PF01061 ABC-2 type transporter 25 231 2.3E-18 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 PANTHER PTHR39420 3 374 5.6E-199 T 16-09-2016 Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 PANTHER PTHR39420:SF1 3 374 5.6E-199 T 16-09-2016 Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 11 370 1.7E-128 T 16-09-2016 IPR018766 Zinicin-like metallopeptidase type 2 Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 Pfam PF10103 Zinicin-like metallopeptidase 11 366 3.2E-122 T 16-09-2016 IPR018766 Zinicin-like metallopeptidase type 2 Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 11 370 6.1E-146 T 16-09-2016 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated Spa2297_RS18165 186c58c67065d1a5530f76d4cb7f193c 375 SUPERFAMILY SSF55486 10 369 3.81E-107 T 16-09-2016 Spa2297_RS00570 b480414b6426859b86ce7f1f45961a56 206 Gene3D G3DSA:3.40.430.10 2 204 3.0E-40 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS00570 b480414b6426859b86ce7f1f45961a56 206 PANTHER PTHR38011:SF1 6 206 5.8E-54 T 16-09-2016 Spa2297_RS00570 b480414b6426859b86ce7f1f45961a56 206 Pfam PF01872 RibD C-terminal domain 8 195 1.7E-32 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS00570 b480414b6426859b86ce7f1f45961a56 206 SUPERFAMILY SSF53597 46 204 2.62E-25 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS00570 b480414b6426859b86ce7f1f45961a56 206 PANTHER PTHR38011 6 206 5.8E-54 T 16-09-2016 Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 96 1.7E-16 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 SUPERFAMILY SSF52091 2 96 1.77E-21 T 16-09-2016 IPR002645 STAS domain Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 PANTHER PTHR33495 1 95 5.2E-23 T 16-09-2016 Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 Gene3D G3DSA:3.30.750.24 2 96 1.7E-26 T 16-09-2016 IPR002645 STAS domain Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 Pfam PF13466 STAS domain 10 89 2.8E-15 T 16-09-2016 IPR002645 STAS domain Spa2297_RS22760 3cfe780a3e99adaad1c7c3bf42f5f07d 107 PANTHER PTHR33495:SF2 1 95 5.2E-23 T 16-09-2016 Spa2297_RS05920 830f40f974cbda0d725ce8c1afc3002f 97 Pfam PF13453 Transcription factor zinc-finger 2 40 3.2E-17 T 16-09-2016 IPR027392 Transcription factor zinc-finger Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 SUPERFAMILY SSF53850 31 445 4.79E-82 T 16-09-2016 Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 Gene3D G3DSA:3.40.190.10 186 375 6.3E-47 T 16-09-2016 Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 PANTHER PTHR30061:SF24 1 452 7.9E-126 T 16-09-2016 Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 Pfam PF01547 Bacterial extracellular solute-binding protein 66 355 1.0E-43 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 PANTHER PTHR30061 1 452 7.9E-126 T 16-09-2016 Spa2297_RS07505 481707f24d26b5df64f986e104844c46 454 Gene3D G3DSA:3.40.190.10 53 185 2.0E-25 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 Gene3D G3DSA:3.40.50.1820 217 354 1.3E-62 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 Gene3D G3DSA:3.40.50.1820 405 525 1.3E-62 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 Gene3D G3DSA:3.40.50.1820 87 173 1.3E-62 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992 394 400 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992 94 172 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992 420 527 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992:SF878 394 400 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 Pfam PF00561 alpha/beta hydrolase fold 122 510 1.2E-34 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992:SF878 420 527 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 SUPERFAMILY SSF53474 219 273 5.11E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 SUPERFAMILY SSF53474 398 511 5.11E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 SUPERFAMILY SSF53474 115 174 5.11E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992:SF878 94 172 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992:SF878 219 306 1.6E-50 T 16-09-2016 Spa2297_RS18010 e7f01e3801740b356257352bfec7d905 538 PANTHER PTHR10992 219 306 1.6E-50 T 16-09-2016 Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 PANTHER PTHR13794 1 369 3.4E-101 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 Gene3D G3DSA:3.30.390.10 1 122 2.2E-24 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 SUPERFAMILY SSF54826 1 118 3.7E-21 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 Pfam PF13378 Enolase C-terminal domain-like 143 347 4.0E-42 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 Gene3D G3DSA:3.20.20.120 123 345 6.5E-52 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 SUPERFAMILY SSF51604 106 352 8.52E-47 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 118 1.4E-7 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 SMART SM00922 137 237 2.2E-15 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS32065 56b35c7b40d5703e281c87ee19472401 380 PANTHER PTHR13794:SF58 1 369 3.4E-101 T 16-09-2016 Spa2297_RS28485 03ed1bc01b2fc2a7485bb83a3adfab3b 358 PANTHER PTHR32196:SF22 8 358 6.7E-124 T 16-09-2016 Spa2297_RS28485 03ed1bc01b2fc2a7485bb83a3adfab3b 358 PANTHER PTHR32196 8 358 6.7E-124 T 16-09-2016 Spa2297_RS28485 03ed1bc01b2fc2a7485bb83a3adfab3b 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 344 3.1E-56 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS09690 4d1363b0635f0c739534275eee491f90 244 SUPERFAMILY SSF53335 8 236 3.1E-42 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09690 4d1363b0635f0c739534275eee491f90 244 PANTHER PTHR10108:SF752 1 181 1.5E-53 T 16-09-2016 Spa2297_RS09690 4d1363b0635f0c739534275eee491f90 244 Gene3D G3DSA:3.40.50.150 7 236 3.2E-49 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09690 4d1363b0635f0c739534275eee491f90 244 PANTHER PTHR10108 1 181 1.5E-53 T 16-09-2016 Spa2297_RS09690 4d1363b0635f0c739534275eee491f90 244 Pfam PF08241 Methyltransferase domain 18 121 7.1E-24 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS11045 fd13242a0dec9ef29745ae2708928c81 118 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 4.7E-33 T 16-09-2016 IPR025327 Protein of unknown function DUF4233 Spa2297_RS19655 f9d9a89984e54f93e6ca3806d3e396fe 430 PANTHER PTHR12468 1 384 1.0E-222 T 16-09-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 Spa2297_RS19655 f9d9a89984e54f93e6ca3806d3e396fe 430 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 128 276 8.8E-6 T 16-09-2016 Spa2297_RS19655 f9d9a89984e54f93e6ca3806d3e396fe 430 PANTHER PTHR12468:SF4 1 384 1.0E-222 T 16-09-2016 Spa2297_RS05445 e4b2ed9ce563b52ccc4fac07d23f4a51 253 PANTHER PTHR14194 1 252 1.9E-108 T 16-09-2016 Spa2297_RS05445 e4b2ed9ce563b52ccc4fac07d23f4a51 253 Gene3D G3DSA:3.40.50.720 2 203 1.9E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05445 e4b2ed9ce563b52ccc4fac07d23f4a51 253 SUPERFAMILY SSF51735 4 212 5.17E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05445 e4b2ed9ce563b52ccc4fac07d23f4a51 253 PANTHER PTHR14194:SF67 1 252 1.9E-108 T 16-09-2016 Spa2297_RS05445 e4b2ed9ce563b52ccc4fac07d23f4a51 253 Pfam PF13460 NAD(P)H-binding 8 131 1.4E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 SUPERFAMILY SSF46785 17 86 2.03E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PRINTS PR01467 Bacterial arginine repressor signature 53 68 7.7E-26 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PRINTS PR01467 Bacterial arginine repressor signature 144 159 7.7E-26 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PRINTS PR01467 Bacterial arginine repressor signature 37 50 7.7E-26 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PRINTS PR01467 Bacterial arginine repressor signature 114 127 7.7E-26 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 Gene3D G3DSA:1.10.10.10 16 88 5.1E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 Gene3D G3DSA:3.30.1360.40 99 174 3.2E-28 T 16-09-2016 IPR024946 Arginine repressor C-terminal-like domain Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 Hamap MF_00173 Arginine repressor [argR]. 1 178 56.061 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 TIGRFAM TIGR01529 argR_whole: arginine repressor 21 174 4.8E-44 T 16-09-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PANTHER PTHR34471 14 179 3.9E-63 T 16-09-2016 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 120 153 4.0E-12 T 16-09-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 SUPERFAMILY SSF55252 108 173 3.27E-18 T 16-09-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 Pfam PF02863 Arginine repressor, C-terminal domain 108 171 2.3E-23 T 16-09-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 Pfam PF01316 Arginine repressor, DNA binding domain 18 85 2.1E-24 T 16-09-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 Spa2297_RS06065 432623d5d0aad12e67ba0d5f946aeb8c 179 PANTHER PTHR34471:SF1 14 179 3.9E-63 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 PANTHER PTHR30177:SF2 368 591 0.0 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:1.10.3720.10 79 261 3.4E-42 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 PANTHER PTHR30177:SF2 2 270 0.0 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 PANTHER PTHR30177 2 270 0.0 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 PANTHER PTHR30177 368 591 0.0 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 SUPERFAMILY SSF53850 335 595 8.31E-74 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.10 609 692 5.0E-58 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.10 539 597 4.0E-66 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.10 335 419 4.0E-66 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.10 812 871 5.0E-58 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.100 423 538 8.6E-35 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Gene3D G3DSA:3.40.190.100 696 811 3.6E-37 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 SUPERFAMILY SSF53850 607 870 1.15E-70 T 16-09-2016 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 338 586 1.0E-65 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 613 860 8.9E-60 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 SUPERFAMILY SSF161098 83 265 1.07E-38 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS06255 8dbc6f2a3ea2518d76565b557be9a7b7 871 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 263 1.3E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07460 504e4e48b2e556d55121f7d1c99d5e25 241 SUPERFAMILY SSF52833 1 212 1.4E-42 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS07460 504e4e48b2e556d55121f7d1c99d5e25 241 PANTHER PTHR13887 1 234 7.9E-60 T 16-09-2016 Spa2297_RS07460 504e4e48b2e556d55121f7d1c99d5e25 241 PANTHER PTHR13887:SF10 1 234 7.9E-60 T 16-09-2016 Spa2297_RS07460 504e4e48b2e556d55121f7d1c99d5e25 241 Pfam PF01323 DSBA-like thioredoxin domain 2 206 2.4E-41 T 16-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Spa2297_RS07460 504e4e48b2e556d55121f7d1c99d5e25 241 Gene3D G3DSA:3.40.30.10 1 210 8.0E-46 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 Pfam PF01078 Magnesium chelatase, subunit ChlI 215 421 3.1E-87 T 16-09-2016 IPR000523 Magnesium chelatase ChlI domain Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 525 7.6E-138 T 16-09-2016 IPR004482 Mg chelatase-related protein Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 Gene3D G3DSA:3.30.230.10 7 168 8.0E-38 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 SUPERFAMILY SSF54211 2 170 7.21E-37 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 Gene3D G3DSA:3.40.50.300 215 415 7.7E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 PANTHER PTHR32039 1 184 3.7E-218 T 16-09-2016 Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 PANTHER PTHR32039:SF7 215 527 3.7E-218 T 16-09-2016 IPR004482 Mg chelatase-related protein Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 431 526 3.2E-21 T 16-09-2016 IPR025158 Mg chelatase-related protein, C-terminal domain Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 SUPERFAMILY SSF52540 215 526 2.87E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 PANTHER PTHR32039:SF7 1 184 3.7E-218 T 16-09-2016 IPR004482 Mg chelatase-related protein Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 5.2E-38 T 16-09-2016 Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 PANTHER PTHR32039 215 527 3.7E-218 T 16-09-2016 Spa2297_RS23795 8df008ae2afa1ae0cabd4243137057cd 541 SMART SM00382 235 419 5.1E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 Gene3D G3DSA:3.60.70.12 2 259 4.6E-94 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 PANTHER PTHR23100 2 383 6.3E-155 T 16-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 383 133.836 T 16-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 Pfam PF01960 ArgJ family 11 383 4.8E-127 T 16-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 18 381 0.0 T 16-09-2016 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 SUPERFAMILY SSF56266 7 379 1.57E-128 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 PANTHER PTHR23100:SF0 2 383 6.3E-155 T 16-09-2016 Spa2297_RS06080 77d095703edf8d2099fee3a3403b807a 383 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 382 1.7E-104 T 16-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 PANTHER PTHR11203 10 561 8.5E-228 T 16-09-2016 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.01 T 16-09-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 SMART SM00849 31 225 8.1E-21 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 SUPERFAMILY SSF56281 19 433 1.24E-95 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 PANTHER PTHR11203:SF22 10 561 8.5E-228 T 16-09-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 1.7E-13 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 PIRSF PIRSF004803 12 561 6.9E-206 T 16-09-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 Gene3D G3DSA:3.60.15.10 18 265 6.9E-77 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 1.8E-150 T 16-09-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 Spa2297_RS24270 106e6acd9c314aa7320d2be9d80c16f1 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 9.8E-10 T 16-09-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 Pfam PF00005 ABC transporter 356 499 1.4E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 PANTHER PTHR24221 22 558 2.3E-145 T 16-09-2016 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 PANTHER PTHR24221:SF161 22 558 2.3E-145 T 16-09-2016 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 SUPERFAMILY SSF52540 331 559 4.11E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 Gene3D G3DSA:3.40.50.300 337 558 1.3E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 Pfam PF00664 ABC transporter transmembrane region 29 283 3.2E-13 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 SUPERFAMILY SSF90123 22 320 5.36E-32 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 Gene3D G3DSA:1.20.1560.10 28 317 1.9E-28 T 16-09-2016 Spa2297_RS27805 5c2f7e92dfa380502887cad83faa2db3 567 SMART SM00382 361 545 8.5E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS02330 09c851d932308c341127420b0c8aaf3c 330 Gene3D G3DSA:3.20.20.100 13 328 2.6E-86 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS02330 09c851d932308c341127420b0c8aaf3c 330 PANTHER PTHR11732:SF191 12 330 9.7E-175 T 16-09-2016 Spa2297_RS02330 09c851d932308c341127420b0c8aaf3c 330 PANTHER PTHR11732 12 330 9.7E-175 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS02330 09c851d932308c341127420b0c8aaf3c 330 Pfam PF00248 Aldo/keto reductase family 27 328 3.0E-68 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS02330 09c851d932308c341127420b0c8aaf3c 330 SUPERFAMILY SSF51430 12 328 2.62E-89 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 PANTHER PTHR33169:SF4 1 187 1.6E-51 T 16-09-2016 Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 SUPERFAMILY SSF46785 3 180 1.87E-38 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 1.6E-11 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 Pfam PF10400 Virulence activator alpha C-term 92 178 2.2E-21 T 16-09-2016 IPR018309 Transcription regulator PadR, C-terminal Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 PANTHER PTHR33169 1 187 1.6E-51 T 16-09-2016 Spa2297_RS31600 7c7b44fa932fc0c1319237f160f71d6b 188 Gene3D G3DSA:1.10.10.10 1 87 7.1E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Pfam PF04023 FeoA domain 154 228 7.2E-7 T 16-09-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 SUPERFAMILY SSF46785 3 62 1.28E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 PANTHER PTHR33238 2 227 7.9E-88 T 16-09-2016 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 PANTHER PTHR33238:SF1 2 227 7.9E-88 T 16-09-2016 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 5.1E-29 T 16-09-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Gene3D G3DSA:1.10.60.10 75 133 9.2E-30 T 16-09-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 SMART SM00899 153 229 1.2E-7 T 16-09-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 SUPERFAMILY SSF47979 65 137 9.81E-26 T 16-09-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.6E-19 T 16-09-2016 IPR022687 DTXR-type HTH domain GO:0003677 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 SUPERFAMILY SSF50037 130 229 2.29E-23 T 16-09-2016 IPR008988 Transcriptional repressor, C-terminal Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 SMART SM00529 26 125 3.2E-47 T 16-09-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Gene3D G3DSA:2.30.30.90 134 229 6.8E-32 T 16-09-2016 Spa2297_RS14455 7fd4473a0c1dbbb0fd6cf8a87915f41c 230 Gene3D G3DSA:1.10.10.10 2 73 5.0E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 PANTHER PTHR10362:SF7 1 479 4.2E-83 T 16-09-2016 Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 Gene3D G3DSA:1.10.275.10 7 164 7.4E-37 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 Pfam PF00221 Aromatic amino acid lyase 14 451 4.8E-119 T 16-09-2016 IPR001106 Aromatic amino acid lyase Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 PANTHER PTHR10362 1 479 4.2E-83 T 16-09-2016 Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 Gene3D G3DSA:1.20.200.10 187 479 2.1E-81 T 16-09-2016 Spa2297_RS00490 84b2f25c2d760f7402196cf099cdb154 483 SUPERFAMILY SSF48557 4 481 2.67E-120 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 ProSitePatterns PS01008 DnaA protein signature. 624 643 - T 16-09-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PANTHER PTHR30050:SF2 328 667 1.8E-195 T 16-09-2016 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 SMART SM00760 574 643 1.1E-35 T 16-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Gene3D G3DSA:1.10.8.60 494 563 2.2E-28 T 16-09-2016 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 SUPERFAMILY SSF52540 327 539 1.76E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Gene3D G3DSA:3.40.50.300 325 492 3.5E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Pfam PF00308 Bacterial dnaA protein 328 545 2.6E-103 T 16-09-2016 IPR013317 Chromosomal replication initiator protein DnaA Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 665 33.361 T 16-09-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Gene3D G3DSA:1.10.1750.10 569 666 3.8E-38 T 16-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 SMART SM00382 360 488 9.9E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 624 643 2.2E-51 T 16-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 425 439 2.2E-51 T 16-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 459 486 2.2E-51 T 16-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 361 381 2.2E-51 T 16-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 393 407 2.2E-51 T 16-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 PANTHER PTHR30050 328 667 1.8E-195 T 16-09-2016 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 323 664 1.8E-148 T 16-09-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 577 643 7.4E-29 T 16-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Spa2297_RS16570 3726c896f6f3084a26f8ce5465941c53 667 SUPERFAMILY SSF48295 571 666 3.66E-34 T 16-09-2016 IPR010921 Trp repressor/replication initiator GO:0043565 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 316 336 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 300 313 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 178 193 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 267 277 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 107 126 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 340 354 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 150 163 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PRINTS PR00733 Glycosyl hydrolase family 6 signature 234 247 1.8E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PANTHER PTHR34876 35 372 4.6E-101 T 16-09-2016 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 SUPERFAMILY SSF51989 88 371 5.36E-84 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 Pfam PF01341 Glycosyl hydrolases family 6 109 355 8.1E-65 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 PIRSF PIRSF001100 6 372 4.0E-83 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS05470 5e654aac18e3d45e5bd60cfade4a5903 372 Gene3D G3DSA:3.20.20.40 88 372 2.4E-85 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 Gene3D G3DSA:3.90.226.10 27 265 7.1E-65 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 Gene3D G3DSA:3.90.226.10 273 521 3.5E-78 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 SUPERFAMILY SSF52096 23 262 2.2E-64 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 PANTHER PTHR22855:SF31 1 532 0.0 T 16-09-2016 Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 Pfam PF01039 Carboxyl transferase domain 48 519 2.9E-136 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 PANTHER PTHR22855 1 532 0.0 T 16-09-2016 Spa2297_RS14505 9475700836f11f2523b231873d8de5b7 532 SUPERFAMILY SSF52096 271 524 1.23E-74 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992:SF878 56 159 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992:SF878 341 366 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992 341 366 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992 206 295 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 Pfam PF08386 TAP-like protein 418 517 6.1E-26 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 Gene3D G3DSA:3.40.50.1820 204 330 4.9E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 Gene3D G3DSA:3.40.50.1820 66 160 4.9E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 Gene3D G3DSA:3.40.50.1820 384 505 4.9E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992:SF878 447 507 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992 56 159 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992 447 507 3.2E-67 T 16-09-2016 Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 SUPERFAMILY SSF53474 109 161 3.13E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 SUPERFAMILY SSF53474 339 505 3.13E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 SUPERFAMILY SSF53474 206 260 3.13E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25425 7996b1f069b8a140f04fac1c7e26b517 527 PANTHER PTHR10992:SF878 206 295 3.2E-67 T 16-09-2016 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 Gene3D G3DSA:1.10.510.10 101 258 1.0E-36 T 16-09-2016 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 Gene3D G3DSA:1.10.510.10 300 367 1.0E-36 T 16-09-2016 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 123 135 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 Gene3D G3DSA:3.30.200.20 3 100 1.2E-17 T 16-09-2016 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 SUPERFAMILY SSF56112 321 378 8.02E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 SUPERFAMILY SSF56112 5 263 8.02E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 SMART SM00220 9 477 2.0E-34 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 Pfam PF00069 Protein kinase domain 9 208 1.5E-36 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 PANTHER PTHR24362:SF160 1 396 1.2E-91 T 16-09-2016 Spa2297_RS16645 7f477284b3a9db132f9b5f3304d2f96f 494 PANTHER PTHR24362 1 396 1.2E-91 T 16-09-2016 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 Pfam PF07690 Major Facilitator Superfamily 23 411 6.2E-47 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 PANTHER PTHR23501 4 508 3.1E-282 T 16-09-2016 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 PANTHER PTHR23501:SF37 4 508 3.1E-282 T 16-09-2016 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 SUPERFAMILY SSF103473 249 420 4.32E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 SUPERFAMILY SSF103473 465 495 4.32E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 SUPERFAMILY SSF103473 5 199 4.32E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 Gene3D G3DSA:1.20.1250.20 16 195 3.2E-27 T 16-09-2016 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 Gene3D G3DSA:1.20.1250.20 467 489 3.0E-13 T 16-09-2016 Spa2297_RS23350 200b0a72c8e0a396c1f54b41609da08f 515 Gene3D G3DSA:1.20.1250.20 271 421 3.0E-13 T 16-09-2016 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Gene3D G3DSA:3.40.50.720 14 107 1.7E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 SUPERFAMILY SSF53244 336 479 4.58E-39 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 PANTHER PTHR23135 10 479 6.1E-155 T 16-09-2016 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 PANTHER PTHR23135:SF2 10 479 6.1E-155 T 16-09-2016 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 SUPERFAMILY SSF51984 14 108 1.26E-16 T 16-09-2016 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 128 151 - T 16-09-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 18 479 34.32 T 16-09-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Pfam PF08245 Mur ligase middle domain 130 315 2.7E-28 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 19 477 3.1E-121 T 16-09-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 337 402 2.3E-6 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Gene3D G3DSA:3.40.1190.10 108 334 2.0E-68 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 SUPERFAMILY SSF53623 124 332 4.06E-49 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08535 00d7c0678d365bd011f25c2d77f8685e 481 Gene3D G3DSA:3.90.190.20 336 476 5.3E-46 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 SUPERFAMILY SSF53474 4 291 1.32E-65 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PANTHER PTHR10992 5 292 1.6E-72 T 16-09-2016 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PANTHER PTHR10992:SF778 5 292 1.6E-72 T 16-09-2016 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PRINTS PR00412 Epoxide hydrolase signature 117 130 1.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 PRINTS PR00412 Epoxide hydrolase signature 267 289 1.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 Gene3D G3DSA:3.40.50.1820 2 291 4.6E-65 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS29125 f6e1ea57f4b91bb46d1fe1df9f36ca00 292 Pfam PF00561 alpha/beta hydrolase fold 31 277 5.3E-21 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 Gene3D G3DSA:3.40.47.10 3 57 2.0E-49 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 Gene3D G3DSA:3.40.47.10 99 246 2.0E-49 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 PANTHER PTHR11877 106 389 2.1E-62 T 16-09-2016 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 SUPERFAMILY SSF53901 103 245 3.95E-32 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 PIRSF PIRSF000451 1 394 7.8E-92 T 16-09-2016 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 SUPERFAMILY SSF53901 230 393 2.09E-16 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 105 242 2.6E-16 T 16-09-2016 IPR001099 Chalcone/stilbene synthase, N-terminal Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 Gene3D G3DSA:3.40.47.10 253 389 6.1E-13 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS31525 8450f8157b3d1d99789b016382fd5283 394 PANTHER PTHR11877:SF10 106 389 2.1E-62 T 16-09-2016 Spa2297_RS01760 eba316d6640457638716a94adba3c740 168 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 1.7E-9 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS01760 eba316d6640457638716a94adba3c740 168 Gene3D G3DSA:3.30.530.20 3 152 1.4E-11 T 16-09-2016 IPR023393 START-like domain Spa2297_RS01760 eba316d6640457638716a94adba3c740 168 SUPERFAMILY SSF55961 3 144 4.18E-20 T 16-09-2016 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PANTHER PTHR11465 5 481 1.1E-284 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 SMART SM01060 7 394 3.1E-275 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 16-09-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 83 101 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 20 43 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 123 141 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 288 315 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 320 346 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PRINTS PR00067 Catalase signature 104 121 1.7E-69 T 16-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 Pfam PF00199 Catalase 7 391 4.3E-185 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 PIRSF PIRSF038928 1 487 9.0E-216 T 16-09-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 16-09-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 Pfam PF06628 Catalase-related immune-responsive 419 481 2.5E-19 T 16-09-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 Gene3D G3DSA:2.40.180.10 2 357 1.5E-179 T 16-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS26295 9ca7f9e0c5c503cda4b4e6b1c4a18fa5 487 SUPERFAMILY SSF56634 3 482 4.71E-203 T 16-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 SUPERFAMILY SSF54862 296 398 2.72E-14 T 16-09-2016 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Pfam PF11870 Domain of unknown function (DUF3390) 393 483 1.4E-15 T 16-09-2016 IPR024569 4Fe-4S binding protein, C-terminal Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Gene3D G3DSA:1.10.1060.10 313 399 1.1E-11 T 16-09-2016 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 PANTHER PTHR32479:SF10 15 486 2.0E-224 T 16-09-2016 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 73 299 1.9E-48 T 16-09-2016 IPR003741 LUD domain Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 20 447 2.2E-134 T 16-09-2016 IPR004452 4Fe-4S binding protein GO:0019516 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Gene3D G3DSA:3.40.50.10420 197 300 5.4E-47 T 16-09-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Gene3D G3DSA:3.40.50.10420 66 129 5.4E-47 T 16-09-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 SUPERFAMILY SSF100950 125 300 8.79E-33 T 16-09-2016 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 Pfam PF13183 4Fe-4S dicluster domain 315 384 1.0E-8 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 PANTHER PTHR32479 15 486 2.0E-224 T 16-09-2016 Spa2297_RS29630 01b33a96e708dd63c1dbdb458ac95f3b 492 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 272 2.1E-59 T 16-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 PIRSF PIRSF005917 1 280 6.0E-88 T 16-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 PANTHER PTHR21091 2 259 3.2E-66 T 16-09-2016 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 Gene3D G3DSA:3.30.950.10 114 225 2.1E-43 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 Gene3D G3DSA:3.40.1010.10 3 113 2.9E-7 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 PANTHER PTHR21091:SF18 2 259 3.2E-66 T 16-09-2016 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.522 T 16-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 SUPERFAMILY SSF53790 3 222 1.03E-72 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS13715 e9adb97184209f665444b709c4ae8f12 282 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 1.8E-30 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 SUPERFAMILY SSF51011 485 561 6.68E-17 T 16-09-2016 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Pfam PF00128 Alpha amylase, catalytic domain 46 402 1.1E-79 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 PANTHER PTHR10357 1 418 2.5E-295 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 6.4E-27 T 16-09-2016 IPR032091 Maltogenic Amylase, C-terminal Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 SMART SM00642 31 433 1.6E-123 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Gene3D G3DSA:2.60.40.1180 481 561 4.6E-15 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Gene3D G3DSA:3.20.20.80 460 474 8.9E-113 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Gene3D G3DSA:3.20.20.80 25 122 8.9E-113 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Gene3D G3DSA:3.20.20.80 198 427 8.9E-113 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 SUPERFAMILY SSF51445 34 481 3.92E-136 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 PANTHER PTHR10357 457 562 2.5E-295 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 PANTHER PTHR10357:SF164 457 562 2.5E-295 T 16-09-2016 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 6.9E-302 T 16-09-2016 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 PANTHER PTHR10357:SF164 1 418 2.5E-295 T 16-09-2016 Spa2297_RS23010 0b5d3b7f1d02ef79172704387d1c920c 566 Gene3D G3DSA:3.90.400.10 123 190 1.2E-24 T 16-09-2016 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 SMART SM01130 11 299 5.3E-61 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 Gene3D G3DSA:3.20.20.70 6 300 6.5E-76 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 SUPERFAMILY SSF51569 15 300 6.91E-66 T 16-09-2016 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 PANTHER PTHR12128:SF34 1 298 5.6E-84 T 16-09-2016 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 PANTHER PTHR12128 1 298 5.6E-84 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 Pfam PF00701 Dihydrodipicolinate synthetase family 13 296 7.6E-45 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07540 dca2812124d00bd17e5b64a1d316d587 302 PIRSF PIRSF001365 7 301 1.8E-58 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 Gene3D G3DSA:3.50.50.60 234 340 3.7E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 SUPERFAMILY SSF51905 221 556 2.11E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 SMART SM00100 20 138 2.9E-17 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 380 398 7.4E-26 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 466 482 7.4E-26 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 257 7.4E-26 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 337 355 7.4E-26 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 511 533 7.4E-26 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 SUPERFAMILY SSF51206 20 145 2.23E-23 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 Pfam PF00027 Cyclic nucleotide-binding domain 39 125 2.4E-13 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PANTHER PTHR22912:SF138 518 560 1.1E-140 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PANTHER PTHR22912:SF138 222 498 1.1E-140 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PANTHER PTHR22912 518 560 1.1E-140 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PANTHER PTHR22912 222 498 1.1E-140 T 16-09-2016 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 Gene3D G3DSA:2.60.120.10 21 140 7.4E-19 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 236 547 3.4E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 285 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 376 400 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 338 346 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 259 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 468 489 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 430 446 6.6E-33 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14065 a778d09d12df5fa968ea667759f0f39a 584 Gene3D G3DSA:3.50.50.60 341 555 6.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 Pfam PF00171 Aldehyde dehydrogenase family 13 459 3.6E-158 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 PANTHER PTHR11699:SF212 1 460 1.5E-241 T 16-09-2016 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 PANTHER PTHR11699 1 460 1.5E-241 T 16-09-2016 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 Gene3D G3DSA:3.40.309.10 258 435 4.1E-59 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 SUPERFAMILY SSF53720 4 460 5.5E-152 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06695 4625edefd219a461ee6db1e00543bd5f 462 Gene3D G3DSA:3.40.605.10 6 257 1.1E-84 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 SUPERFAMILY SSF74650 3 324 1.63E-113 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 172 181 - T 16-09-2016 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 Pfam PF01263 Aldose 1-epimerase 16 321 1.9E-93 T 16-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 PANTHER PTHR10091 1 326 9.0E-153 T 16-09-2016 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 PANTHER PTHR10091:SF0 1 326 9.0E-153 T 16-09-2016 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 Gene3D G3DSA:2.70.98.10 2 324 8.7E-121 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS10065 96d884d78ce3deea32bb193f2bdd1280 326 PIRSF PIRSF005096 1 326 3.0E-113 T 16-09-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 Gene3D G3DSA:3.30.565.10 325 476 3.1E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 SUPERFAMILY SSF55874 309 477 2.1E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 SMART SM00387 364 475 4.5E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 474 2.9E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 Gene3D G3DSA:2.60.120.10 15 134 2.7E-13 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423 4 44 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423 112 185 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423 286 496 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423:SF555 4 44 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423:SF555 112 185 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 PANTHER PTHR24423:SF555 286 496 5.5E-138 T 16-09-2016 Spa2297_RS02200 357233561c66da71a501825eed1a991f 496 SUPERFAMILY SSF51206 13 134 2.49E-14 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS16770 b02a8467224643556a23ea67363c7556 109 Pfam PF00581 Rhodanese-like domain 11 93 6.0E-12 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS16770 b02a8467224643556a23ea67363c7556 109 SMART SM00450 1 97 6.4E-16 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS16770 b02a8467224643556a23ea67363c7556 109 Gene3D G3DSA:3.40.250.10 13 102 3.2E-26 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS16770 b02a8467224643556a23ea67363c7556 109 SUPERFAMILY SSF52821 12 102 1.7E-28 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03130 bd39ed4ee5e42e6b277a812b10549bd2 278 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 264 7.2E-73 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS03130 bd39ed4ee5e42e6b277a812b10549bd2 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 271 17.359 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS03130 bd39ed4ee5e42e6b277a812b10549bd2 278 PANTHER PTHR30622:SF3 2 278 3.4E-115 T 16-09-2016 Spa2297_RS03130 bd39ed4ee5e42e6b277a812b10549bd2 278 PANTHER PTHR30622 2 278 3.4E-115 T 16-09-2016 Spa2297_RS03130 bd39ed4ee5e42e6b277a812b10549bd2 278 Pfam PF02673 Bacitracin resistance protein BacA 9 266 2.7E-71 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Gene3D G3DSA:3.40.50.10490 246 445 1.0E-75 T 16-09-2016 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Pfam PF13522 Glutamine amidotransferase domain 67 194 1.2E-21 T 16-09-2016 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 SUPERFAMILY SSF56235 2 234 8.58E-66 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Pfam PF01380 SIS domain 292 418 6.6E-35 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Pfam PF01380 SIS domain 464 596 4.0E-23 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 9.8E-248 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 PANTHER PTHR10937:SF0 1 615 0.0 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Gene3D G3DSA:3.60.20.10 2 242 1.7E-73 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Gene3D G3DSA:3.40.50.10490 446 615 1.7E-60 T 16-09-2016 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 41.465 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 PANTHER PTHR10937 1 615 0.0 T 16-09-2016 Spa2297_RS19985 a4206f63b07bebee6671c8cc211f2d3b 615 SUPERFAMILY SSF53697 247 615 1.76E-109 T 16-09-2016 Spa2297_RS20685 b291a808da54308e842e71168e0d928d 374 PANTHER PTHR32196:SF30 1 357 6.4E-114 T 16-09-2016 Spa2297_RS20685 b291a808da54308e842e71168e0d928d 374 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 332 5.6E-39 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS20685 b291a808da54308e842e71168e0d928d 374 PANTHER PTHR32196 1 357 6.4E-114 T 16-09-2016 Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SMART SM00487 17 300 8.0E-4 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 PANTHER PTHR11472 21 633 1.0E-189 T 16-09-2016 Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Gene3D G3DSA:3.40.50.300 189 261 2.8E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Gene3D G3DSA:3.40.50.300 10 83 2.8E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Gene3D G3DSA:3.40.50.300 142 143 2.8E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Gene3D G3DSA:3.40.50.300 394 403 2.8E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Gene3D G3DSA:3.40.50.300 465 612 3.0E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 Pfam PF13307 Helicase C-terminal domain 471 630 7.3E-28 T 16-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 PANTHER PTHR11472:SF37 21 633 1.0E-189 T 16-09-2016 Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SUPERFAMILY SSF52540 189 260 2.16E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SUPERFAMILY SSF52540 392 406 2.16E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SUPERFAMILY SSF52540 34 85 2.16E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SUPERFAMILY SSF52540 445 601 2.16E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24565 842ca3b79a1da7e5cf10796ec08002d2 659 SMART SM00491 488 618 1.5E-43 T 16-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PIRSF PIRSF000097 2 275 7.5E-90 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PRINTS PR00069 Aldo-keto reductase signature 94 112 1.2E-48 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PRINTS PR00069 Aldo-keto reductase signature 160 189 1.2E-48 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PRINTS PR00069 Aldo-keto reductase signature 126 143 1.2E-48 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PRINTS PR00069 Aldo-keto reductase signature 198 222 1.2E-48 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.2E-48 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 Gene3D G3DSA:3.20.20.100 9 273 8.8E-107 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 SUPERFAMILY SSF51430 8 267 6.81E-97 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 PANTHER PTHR11732 5 272 4.2E-144 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS27265 1db7feb54fae1b00520db2b95e3435a8 277 Pfam PF00248 Aldo/keto reductase family 19 263 9.3E-51 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 Gene3D G3DSA:3.40.50.80 151 254 6.0E-23 T 16-09-2016 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 Gene3D G3DSA:3.10.20.30 255 350 3.7E-24 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 343 4.0E-11 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PANTHER PTHR19370:SF113 17 277 7.5E-77 T 16-09-2016 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 SUPERFAMILY SSF54292 251 350 9.31E-23 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PANTHER PTHR19370 17 277 7.5E-77 T 16-09-2016 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 Pfam PF00175 Oxidoreductase NAD-binding domain 153 243 8.8E-7 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 131 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 229 237 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 107 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 152 171 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 93 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 71 81 3.9E-30 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 SUPERFAMILY SSF52343 139 262 9.43E-22 T 16-09-2016 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 303 311 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 Gene3D G3DSA:2.40.30.10 48 141 2.3E-27 T 16-09-2016 Spa2297_RS09280 33a3f4671a5db83466d5140ff0085b3d 352 SUPERFAMILY SSF63380 49 141 5.38E-24 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Gene3D G3DSA:1.20.58.100 468 579 3.3E-33 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 SUPERFAMILY SSF51905 393 468 1.42E-66 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 SUPERFAMILY SSF51905 6 270 1.42E-66 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PANTHER PTHR11632 318 622 0.0 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 SUPERFAMILY SSF56425 243 389 1.64E-34 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PANTHER PTHR11632 4 301 0.0 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Gene3D G3DSA:3.50.50.60 5 249 4.2E-104 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Gene3D G3DSA:3.50.50.60 385 450 4.2E-104 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 SUPERFAMILY SSF46977 487 642 3.79E-39 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PIRSF PIRSF000171 1 615 5.2E-37 T 16-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Pfam PF00890 FAD binding domain 10 430 1.3E-90 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 496 516 3.1E-6 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.1E-6 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PANTHER PTHR11632:SF56 4 301 0.0 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PANTHER PTHR11632:SF56 318 622 0.0 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Pfam PF02910 Fumarate reductase flavoprotein C-term 494 591 3.8E-24 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 7.4E-7 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.4E-7 T 16-09-2016 Spa2297_RS21535 0ec140e1ed594ec522adfac9bc6d5c9d 645 Gene3D G3DSA:3.90.700.10 250 383 1.5E-35 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 PANTHER PTHR23309:SF6 8 722 0.0 T 16-09-2016 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Gene3D G3DSA:1.10.1040.10 506 604 4.6E-10 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Gene3D G3DSA:1.10.1040.10 645 722 3.7E-8 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 206 9.5E-30 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 SUPERFAMILY SSF48179 632 722 5.87E-16 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 323 501 1.1E-63 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 504 604 4.2E-17 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 PANTHER PTHR23309 8 722 0.0 T 16-09-2016 Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Gene3D G3DSA:3.40.50.720 318 505 7.4E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 SUPERFAMILY SSF51735 320 502 5.13E-57 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 SUPERFAMILY SSF52096 3 310 2.02E-60 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Gene3D G3DSA:3.90.226.10 241 300 9.4E-53 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 Gene3D G3DSA:3.90.226.10 5 207 9.4E-53 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS28035 9e152ca35ad56a7de04f557e21ae95e4 726 SUPERFAMILY SSF48179 503 645 3.74E-14 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS33405 31e9497333338add4a5a24c904da2faf 93 PANTHER PTHR11695:SF601 1 93 4.1E-26 T 16-09-2016 Spa2297_RS33405 31e9497333338add4a5a24c904da2faf 93 PANTHER PTHR11695 1 93 4.1E-26 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS33405 31e9497333338add4a5a24c904da2faf 93 Pfam PF00107 Zinc-binding dehydrogenase 31 92 1.1E-7 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS33405 31e9497333338add4a5a24c904da2faf 93 SUPERFAMILY SSF51735 1 89 2.85E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS33405 31e9497333338add4a5a24c904da2faf 93 Gene3D G3DSA:3.40.50.720 7 89 2.2E-21 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01295 bb05bf62c08d8e309bb6b8f8fdc664a6 266 PANTHER PTHR12110:SF13 1 263 5.8E-138 T 16-09-2016 Spa2297_RS01295 bb05bf62c08d8e309bb6b8f8fdc664a6 266 Gene3D G3DSA:3.20.20.150 7 262 5.8E-63 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS01295 bb05bf62c08d8e309bb6b8f8fdc664a6 266 SUPERFAMILY SSF51658 1 262 2.23E-50 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS01295 bb05bf62c08d8e309bb6b8f8fdc664a6 266 PANTHER PTHR12110 1 263 5.8E-138 T 16-09-2016 Spa2297_RS01295 bb05bf62c08d8e309bb6b8f8fdc664a6 266 Pfam PF01261 Xylose isomerase-like TIM barrel 21 216 1.3E-29 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 Gene3D G3DSA:3.60.120.10 13 491 2.8E-174 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 Pfam PF00425 chorismate binding enzyme 229 480 1.3E-97 T 16-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 6.4E-32 T 16-09-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PRINTS PR00095 Anthranilate synthase component I signature 328 341 1.0E-23 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PRINTS PR00095 Anthranilate synthase component I signature 342 355 1.0E-23 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PRINTS PR00095 Anthranilate synthase component I signature 437 451 1.0E-23 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PRINTS PR00095 Anthranilate synthase component I signature 422 436 1.0E-23 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PANTHER PTHR11236 1 494 1.7E-243 T 16-09-2016 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 489 1.5E-172 T 16-09-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 PANTHER PTHR11236:SF9 1 494 1.7E-243 T 16-09-2016 Spa2297_RS08325 0373be68f5491e1a3ec81434e698aa8a 496 SUPERFAMILY SSF56322 14 489 4.84E-157 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS26635 192b3a71a69e47be913096774f6e5891 205 Gene3D G3DSA:3.90.470.20 83 136 2.4E-13 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26635 192b3a71a69e47be913096774f6e5891 205 PANTHER PTHR12215 16 133 5.6E-16 T 16-09-2016 Spa2297_RS26635 192b3a71a69e47be913096774f6e5891 205 Gene3D G3DSA:3.90.470.20 16 82 7.4E-10 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26635 192b3a71a69e47be913096774f6e5891 205 SUPERFAMILY SSF56214 74 186 9.42E-17 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26635 192b3a71a69e47be913096774f6e5891 205 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 74 135 1.1E-10 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 Gene3D G3DSA:3.50.50.60 118 342 2.8E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 1.5E-5 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 1.5E-5 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.5E-5 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 Gene3D G3DSA:3.50.50.60 6 117 3.8E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PANTHER PTHR22912 169 343 7.1E-17 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PANTHER PTHR22912 1 146 7.1E-17 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 334 2.0E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 3.1E-11 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.1E-11 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 3.1E-11 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.1E-11 T 16-09-2016 Spa2297_RS02085 48ab175bbb7c4b121fa93bd57ad4ff06 456 SUPERFAMILY SSF51905 2 344 5.96E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 SUPERFAMILY SSF52518 4 180 1.81E-37 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 522 8.8E-26 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 PANTHER PTHR18968 5 522 4.7E-107 T 16-09-2016 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 323 4.7E-25 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 SUPERFAMILY SSF52467 159 348 1.73E-37 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Gene3D G3DSA:3.40.50.970 5 176 1.8E-42 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 16-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Gene3D G3DSA:3.40.50.970 368 525 2.4E-40 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Gene3D G3DSA:3.40.50.1220 186 367 8.8E-41 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 174 1.4E-38 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS11955 b6cb431fee4463a8b3c524f673f0ce58 543 SUPERFAMILY SSF52518 356 525 1.09E-40 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 SUPERFAMILY SSF46785 7 152 7.37E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 Pfam PF12802 MarR family 40 100 5.0E-11 T 16-09-2016 Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 Gene3D G3DSA:1.10.10.10 3 153 2.8E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 SMART SM00347 34 136 1.5E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 PANTHER PTHR33164:SF1 8 158 4.2E-53 T 16-09-2016 Spa2297_RS22855 9db66989dcea46912a9ee29435b19d4c 158 PANTHER PTHR33164 8 158 4.2E-53 T 16-09-2016 Spa2297_RS32050 a7ff64f73981decc7e6085d5cc5efd7e 390 PANTHER PTHR11820 181 377 1.3E-82 T 16-09-2016 Spa2297_RS32050 a7ff64f73981decc7e6085d5cc5efd7e 390 PANTHER PTHR11820:SF82 181 377 1.3E-82 T 16-09-2016 Spa2297_RS32050 a7ff64f73981decc7e6085d5cc5efd7e 390 SUPERFAMILY SSF56529 162 368 5.1E-23 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS32050 a7ff64f73981decc7e6085d5cc5efd7e 390 Gene3D G3DSA:3.90.850.10 178 365 3.0E-20 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS24075 3f975c99a13417c5b644b276e74bd198 137 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 97 - T 16-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spa2297_RS24075 3f975c99a13417c5b644b276e74bd198 137 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 99 2.8E-7 T 16-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 Spa2297_RS24075 3f975c99a13417c5b644b276e74bd198 137 Gene3D G3DSA:3.40.140.10 9 132 4.8E-30 T 16-09-2016 Spa2297_RS24075 3f975c99a13417c5b644b276e74bd198 137 SUPERFAMILY SSF53927 10 127 9.03E-27 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS24075 3f975c99a13417c5b644b276e74bd198 137 PANTHER PTHR11644 31 136 5.2E-24 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 SUPERFAMILY SSF51905 17 326 9.93E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 SUPERFAMILY SSF51905 437 469 9.93E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 Gene3D G3DSA:3.40.50.720 14 57 1.3E-12 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 Pfam PF01593 Flavin containing amine oxidoreductase 25 468 1.1E-50 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 SUPERFAMILY SSF54373 310 420 3.34E-28 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 PRINTS PR00419 Adrenodoxin reductase family signature 40 53 2.7E-5 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 PRINTS PR00419 Adrenodoxin reductase family signature 17 39 2.7E-5 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 Gene3D G3DSA:1.10.3110.10 126 208 4.5E-21 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 PANTHER PTHR10742:SF262 5 470 6.6E-304 T 16-09-2016 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 Gene3D G3DSA:3.90.660.20 247 420 6.9E-37 T 16-09-2016 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 17 467 1.0E-63 T 16-09-2016 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25415 3adee91c7597492c71680b875dc56f13 482 PANTHER PTHR10742 5 470 6.6E-304 T 16-09-2016 Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 9.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 9.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 9.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 1.3E-58 T 16-09-2016 Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PANTHER PTHR24322 13 143 2.6E-50 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PANTHER PTHR24322 160 191 2.6E-50 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 203 0.0033 T 16-09-2016 Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 Gene3D G3DSA:3.40.50.720 3 254 5.3E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10500 deb9c33ae0289a606ba99cd811c1701e 255 SUPERFAMILY SSF51735 4 255 1.79E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 5.5E-91 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 Gene3D G3DSA:3.40.50.1370 143 288 6.1E-48 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PANTHER PTHR11405 1 313 2.2E-135 T 16-09-2016 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 3.4E-30 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.243 T 16-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PANTHER PTHR11405:SF16 1 313 2.2E-135 T 16-09-2016 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.9E-39 T 16-09-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 SUPERFAMILY SSF53671 2 312 6.15E-92 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 Gene3D G3DSA:3.40.50.1370 2 142 3.9E-49 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 309 5.7E-22 T 16-09-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.4E-19 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 2.4E-19 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.4E-19 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS05605 5b2babdc1ff75e0775563fc29c9a7355 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 2.4E-19 T 16-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spa2297_RS21185 cd6d3e5e3eb6e8ab551da22806570616 314 PANTHER PTHR35007 25 314 3.9E-91 T 16-09-2016 Spa2297_RS21185 cd6d3e5e3eb6e8ab551da22806570616 314 Pfam PF00482 Type II secretion system (T2SS), protein F 147 266 8.0E-17 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS21185 cd6d3e5e3eb6e8ab551da22806570616 314 PANTHER PTHR35007:SF1 25 314 3.9E-91 T 16-09-2016 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 Gene3D G3DSA:3.90.550.10 2 201 3.4E-47 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 SUPERFAMILY SSF53448 2 229 1.69E-51 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 Pfam PF00535 Glycosyl transferase family 2 5 121 5.1E-32 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 PANTHER PTHR22916 407 507 1.4E-166 T 16-09-2016 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 PANTHER PTHR22916 2 390 1.4E-166 T 16-09-2016 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 SUPERFAMILY SSF53756 482 714 1.1E-15 T 16-09-2016 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 348 715 1.6E-113 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 PANTHER PTHR22916:SF3 407 507 1.4E-166 T 16-09-2016 Spa2297_RS12895 9bf97c77129634225cd2c19eb97f5c52 744 PANTHER PTHR22916:SF3 2 390 1.4E-166 T 16-09-2016 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 PANTHER PTHR11808:SF49 22 394 4.1E-158 T 16-09-2016 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 Gene3D G3DSA:3.40.640.10 24 274 1.2E-70 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 SUPERFAMILY SSF53383 63 390 3.06E-80 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 Gene3D G3DSA:3.90.1150.10 275 390 1.5E-27 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 389 1.2E-90 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 PANTHER PTHR11808 22 394 4.1E-158 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS04730 00c2d8dc3542465baa7fc47ec749d462 407 PIRSF PIRSF001434 15 392 2.0E-113 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 SUPERFAMILY SSF56784 97 262 1.38E-11 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 PANTHER PTHR31284 70 265 2.9E-65 T 16-09-2016 Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 82 263 8.3E-30 T 16-09-2016 IPR005519 Acid phosphatase, class B-like Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 Gene3D G3DSA:3.40.50.1000 74 247 3.6E-14 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 PIRSF PIRSF002674 1 265 1.2E-65 T 16-09-2016 IPR014403 Vegetative storage protein/acid phosphatase Spa2297_RS07495 32a27b0db38388486764d6670e21883f 265 PANTHER PTHR31284:SF10 70 265 2.9E-65 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 Gene3D G3DSA:1.10.260.40 1 55 1.4E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 Gene3D G3DSA:3.40.50.2300 56 164 3.6E-31 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 Pfam PF13377 Periplasmic binding protein-like domain 163 329 6.5E-29 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 PANTHER PTHR30146 1 332 2.6E-107 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 SUPERFAMILY SSF47413 1 54 1.97E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 43 2.6E-13 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 PANTHER PTHR30146:SF30 1 332 2.6E-107 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 Gene3D G3DSA:3.40.50.2300 165 331 1.9E-48 T 16-09-2016 Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 SUPERFAMILY SSF53822 56 330 8.64E-60 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS15395 cc04a753bce3ec730a5e75056aaa62d5 332 SMART SM00354 1 66 1.2E-22 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 PANTHER PTHR10992:SF107 50 295 1.5E-32 T 16-09-2016 Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 SUPERFAMILY SSF53474 51 291 1.35E-31 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 Gene3D G3DSA:3.40.50.1820 217 291 4.8E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 Gene3D G3DSA:3.40.50.1820 51 177 4.8E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 PANTHER PTHR10992 50 295 1.5E-32 T 16-09-2016 Spa2297_RS18820 227c6246f858253e539d886b2a4f1e3c 300 Pfam PF00561 alpha/beta hydrolase fold 72 185 2.4E-11 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 PIRSF PIRSF001413 8 407 1.7E-157 T 16-09-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 SUPERFAMILY SSF53686 15 402 3.4E-146 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 65 390 1.0E-53 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 PANTHER PTHR10314:SF3 19 398 6.5E-224 T 16-09-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 PANTHER PTHR10314 19 398 6.5E-224 T 16-09-2016 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 2.5E-183 T 16-09-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 16-09-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 51.27 T 16-09-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 Gene3D G3DSA:3.40.50.1100 111 189 9.5E-23 T 16-09-2016 Spa2297_RS08300 051b7aa3403704ef224c502b2e189e91 428 Gene3D G3DSA:3.40.50.1100 190 404 1.8E-98 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 Pfam PF06224 Winged helix DNA-binding domain 45 422 2.2E-40 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479 2 78 1.2E-105 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479 94 287 1.2E-105 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479 315 439 1.2E-105 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479:SF2 2 78 1.2E-105 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479:SF2 94 287 1.2E-105 T 16-09-2016 Spa2297_RS21275 e97b9008bd887525f7130a472305838b 441 PANTHER PTHR38479:SF2 315 439 1.2E-105 T 16-09-2016 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 Pfam PF13456 Reverse transcriptase-like 9 130 8.4E-17 T 16-09-2016 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 Gene3D G3DSA:3.30.420.10 3 134 6.1E-22 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 SMART SM00855 292 449 3.5E-14 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 SUPERFAMILY SSF53098 4 129 5.44E-30 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 PANTHER PTHR23029 232 494 6.0E-134 T 16-09-2016 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 SUPERFAMILY SSF53254 291 493 1.35E-50 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 Gene3D G3DSA:3.40.50.1240 290 494 5.9E-53 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 293 488 1.1E-54 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS09615 722144c3db7b954ac6cbe6a621a07733 494 PANTHER PTHR23029:SF34 232 494 6.0E-134 T 16-09-2016 Spa2297_RS06975 85c3e8bda7376a8d75075751fe659c4b 305 Pfam PF02616 Segregation and condensation protein ScpA 59 279 1.7E-51 T 16-09-2016 IPR003768 Segregation and condensation protein A Spa2297_RS06975 85c3e8bda7376a8d75075751fe659c4b 305 PANTHER PTHR33969 26 299 8.5E-75 T 16-09-2016 Spa2297_RS06975 85c3e8bda7376a8d75075751fe659c4b 305 PANTHER PTHR33969:SF2 26 299 8.5E-75 T 16-09-2016 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.0E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.0E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 Gene3D G3DSA:3.40.50.1360 76 225 2.2E-12 T 16-09-2016 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 Pfam PF00455 DeoR C terminal sensor domain 75 239 2.8E-50 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 SUPERFAMILY SSF46785 4 66 3.88E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 SUPERFAMILY SSF100950 76 240 8.69E-25 T 16-09-2016 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 Gene3D G3DSA:1.10.10.10 1 57 4.8E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 16-09-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 SMART SM01134 72 240 1.5E-58 T 16-09-2016 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 SMART SM00420 6 58 1.1E-12 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 PANTHER PTHR30363:SF13 1 260 2.4E-91 T 16-09-2016 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.6E-15 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS03495 bbbe0b40c8b9513c5fa0c4aac891c1c7 261 PANTHER PTHR30363 1 260 2.4E-91 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.3E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 137 4.3E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 168 192 4.3E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 Gene3D G3DSA:3.50.50.60 6 149 1.9E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 208 6.9E-23 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 SUPERFAMILY SSF51905 5 226 7.67E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PANTHER PTHR23023 4 291 4.2E-76 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PANTHER PTHR23023:SF4 4 291 4.2E-76 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 297 1.1E-8 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.1E-8 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.1E-8 T 16-09-2016 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 Gene3D G3DSA:3.50.50.60 255 287 3.1E-24 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 Gene3D G3DSA:3.50.50.60 150 209 3.1E-24 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 SUPERFAMILY SSF51905 267 353 2.98E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04065 5592e6034d414d9f05843be635b3a6cc 359 SUPERFAMILY SSF51905 172 236 2.98E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 SUPERFAMILY SSF48013 23 183 1.31E-34 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 Gene3D G3DSA:3.40.50.150 265 473 3.5E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 354 366 5.4E-19 T 16-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 288 298 5.4E-19 T 16-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 404 420 5.4E-19 T 16-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 456 473 5.4E-19 T 16-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 269 5.4E-19 T 16-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 Pfam PF01189 16S rRNA methyltransferase RsmB/F 284 471 1.5E-44 T 16-09-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PANTHER PTHR22807:SF30 59 473 4.1E-95 T 16-09-2016 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 353 364 - T 16-09-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 SUPERFAMILY SSF53335 171 473 3.17E-50 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 PANTHER PTHR22807 59 473 4.1E-95 T 16-09-2016 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 Pfam PF01029 NusB family 23 152 1.3E-25 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS05530 0549aab93e40e23039114b1512b0f255 475 Gene3D G3DSA:1.10.940.10 20 185 6.8E-47 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS30665 4b442dfe89cdfb4983d6583ff7f39fce 201 Pfam PF03358 NADPH-dependent FMN reductase 1 154 4.0E-17 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS30665 4b442dfe89cdfb4983d6583ff7f39fce 201 Gene3D G3DSA:3.40.50.360 1 163 5.6E-18 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS30665 4b442dfe89cdfb4983d6583ff7f39fce 201 PANTHER PTHR10204:SF48 1 197 5.2E-23 T 16-09-2016 Spa2297_RS30665 4b442dfe89cdfb4983d6583ff7f39fce 201 PANTHER PTHR10204 1 197 5.2E-23 T 16-09-2016 Spa2297_RS30665 4b442dfe89cdfb4983d6583ff7f39fce 201 SUPERFAMILY SSF52218 1 183 1.65E-29 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 Hamap MF_01282 Virginiamycin B lyase [vgb]. 21 308 44.769 T 16-09-2016 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 Gene3D G3DSA:2.120.10.30 85 303 1.6E-32 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 PANTHER PTHR40274:SF2 16 308 1.8E-71 T 16-09-2016 Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 SUPERFAMILY SSF101898 21 267 5.75E-40 T 16-09-2016 Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 PANTHER PTHR40274 16 308 1.8E-71 T 16-09-2016 Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 Gene3D G3DSA:2.120.10.30 24 84 3.1E-8 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS02585 e78f1891b6fb502a85334d6509811f83 309 PIRSF PIRSF026412 7 309 2.0E-102 T 16-09-2016 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Gene3D G3DSA:3.40.50.300 95 363 1.0E-103 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Gene3D G3DSA:1.10.1140.10 364 479 5.2E-44 T 16-09-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 SMART SM00382 160 346 3.2E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Gene3D G3DSA:2.40.10.170 12 93 2.9E-30 T 16-09-2016 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 15 479 3.2E-237 T 16-09-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 SUPERFAMILY SSF52540 96 366 8.12E-89 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 148 361 8.2E-65 T 16-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 PANTHER PTHR15184 13 479 0.0 T 16-09-2016 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 PANTHER PTHR15184:SF8 13 479 0.0 T 16-09-2016 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 92 6.5E-23 T 16-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 352 361 - T 16-09-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 SUPERFAMILY SSF50615 15 93 2.25E-25 T 16-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 SUPERFAMILY SSF47917 364 479 1.31E-45 T 16-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22700 bd617b2da0dcff35f14ed52490da4ceb 482 Hamap MF_01347 ATP synthase subunit beta [atpB]. 13 479 54.462 T 16-09-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 Pfam PF00005 ABC transporter 23 165 3.4E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 Gene3D G3DSA:3.40.50.300 5 239 4.3E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 PANTHER PTHR24220 9 245 4.3E-112 T 16-09-2016 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 PANTHER PTHR24220:SF150 9 245 4.3E-112 T 16-09-2016 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 SUPERFAMILY SSF52540 8 248 7.84E-83 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 SUPERFAMILY SSF50331 242 347 1.02E-13 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 Pfam PF08402 TOBE domain 276 346 5.0E-12 T 16-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS12175 71bb6faffe9bde68db9dc1a5eac3f4c9 353 SMART SM00382 32 216 2.9E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 Gene3D G3DSA:3.30.420.40 7 108 2.5E-6 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 SUPERFAMILY SSF53067 7 112 3.56E-16 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 PANTHER PTHR12862 8 308 2.3E-135 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 SUPERFAMILY SSF53067 118 308 7.78E-34 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 PANTHER PTHR12862:SF4 8 308 2.3E-135 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 Gene3D G3DSA:3.30.420.40 190 291 9.5E-8 T 16-09-2016 Spa2297_RS11275 9539906b7d070c531c46f587a5ec7c18 323 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 303 3.4E-18 T 16-09-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Gene3D G3DSA:1.10.287.130 266 337 4.5E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SMART SM00304 192 244 1.2E-6 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SUPERFAMILY SSF55874 330 496 1.57E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 338 1.7E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 495 3.1E-12 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 3.1E-12 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 476 3.1E-12 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SMART SM00387 383 498 1.0E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Pfam PF00672 HAMP domain 173 240 9.0E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Gene3D G3DSA:3.30.565.10 347 500 3.6E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 383 496 5.8E-24 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PANTHER PTHR24423:SF518 3 11 4.0E-79 T 16-09-2016 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PANTHER PTHR24423:SF518 252 495 4.0E-79 T 16-09-2016 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 Pfam PF05227 CHASE3 domain 24 154 1.9E-25 T 16-09-2016 IPR007891 CHASE3 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SUPERFAMILY SSF47384 260 339 1.12E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SMART SM00388 273 341 6.6E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PANTHER PTHR24423 3 11 4.0E-79 T 16-09-2016 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 PANTHER PTHR24423 252 495 4.0E-79 T 16-09-2016 Spa2297_RS31655 f6fca00795aaa728514d63140ee02deb 514 SUPERFAMILY SSF158472 194 240 5.49E-5 T 16-09-2016 Spa2297_RS08215 20965768a9b7a2799f0d6e6e0b122a22 110 SUPERFAMILY SSF48600 13 102 6.26E-25 T 16-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS08215 20965768a9b7a2799f0d6e6e0b122a22 110 Pfam PF01817 Chorismate mutase type II 23 97 3.0E-17 T 16-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS08215 20965768a9b7a2799f0d6e6e0b122a22 110 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 15 107 2.8E-51 T 16-09-2016 IPR010951 Chorismate mutase, bacteria Spa2297_RS08215 20965768a9b7a2799f0d6e6e0b122a22 110 Gene3D G3DSA:1.20.59.10 13 101 7.9E-21 T 16-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS08215 20965768a9b7a2799f0d6e6e0b122a22 110 SMART SM00830 23 103 1.3E-22 T 16-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 PANTHER PTHR34697:SF1 1 319 8.0E-177 T 16-09-2016 Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 9 301 2.3E-63 T 16-09-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 PANTHER PTHR34697 1 319 8.0E-177 T 16-09-2016 Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 SUPERFAMILY SSF55729 117 250 2.86E-15 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 SUPERFAMILY SSF55729 281 314 2.86E-15 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04705 cf20b1a82eba2deaafc53c13ba7bc0e4 320 Gene3D G3DSA:3.40.630.30 131 236 8.0E-4 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 PANTHER PTHR33692 3 181 6.2E-54 T 16-09-2016 Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 22.72 T 16-09-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 Gene3D G3DSA:2.40.30.60 3 83 1.1E-20 T 16-09-2016 IPR002676 RimM protein GO:0006364 Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 SUPERFAMILY SSF50346 96 166 3.34E-17 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 SUPERFAMILY SSF50447 3 85 1.27E-17 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 Pfam PF01782 RimM N-terminal domain 5 83 3.7E-22 T 16-09-2016 IPR002676 RimM protein GO:0006364 Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 Gene3D G3DSA:2.30.30.240 96 166 6.5E-18 T 16-09-2016 Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 Pfam PF05239 PRC-barrel domain 93 166 6.6E-11 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS23750 372e037b025e2d003ea6f3e640a9a700 187 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.3E-43 T 16-09-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PANTHER PTHR24322 19 150 3.3E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PANTHER PTHR24322 166 197 3.3E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 Gene3D G3DSA:3.40.50.720 9 259 1.5E-81 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 257 3.3E-60 T 16-09-2016 Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.1E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 3.1E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.1E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 SUPERFAMILY SSF51735 13 258 1.15E-77 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 7.9E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15890 d167509d561e3b3518b6ad58b314d311 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 197 0.0023 T 16-09-2016 Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 PANTHER PTHR11907 64 97 5.0E-20 T 16-09-2016 Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 SUPERFAMILY SSF53271 122 232 2.15E-10 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 PANTHER PTHR11907:SF9 122 232 5.0E-20 T 16-09-2016 Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 PANTHER PTHR11907:SF9 64 97 5.0E-20 T 16-09-2016 Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 PANTHER PTHR11907 122 232 5.0E-20 T 16-09-2016 Spa2297_RS13000 dbebe5fd9e948f48ec630e958c91c1ec 306 Gene3D G3DSA:3.40.50.2020 122 232 5.0E-11 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS08160 dd9d9e835e7b6887542ccc35b77fe339 410 PANTHER PTHR30483:SF20 1 400 2.6E-114 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS08160 dd9d9e835e7b6887542ccc35b77fe339 410 Gene3D G3DSA:3.40.50.2300 41 250 1.2E-56 T 16-09-2016 Spa2297_RS08160 dd9d9e835e7b6887542ccc35b77fe339 410 PANTHER PTHR30483 1 400 2.6E-114 T 16-09-2016 Spa2297_RS08160 dd9d9e835e7b6887542ccc35b77fe339 410 Pfam PF13458 Periplasmic binding protein 41 398 1.2E-54 T 16-09-2016 IPR028081 Leucine-binding protein domain Spa2297_RS08160 dd9d9e835e7b6887542ccc35b77fe339 410 SUPERFAMILY SSF53822 41 403 8.83E-81 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS18235 9f26cc5d1ddbe81a64d1cf2e6dbae044 176 PANTHER PTHR34473 22 172 6.9E-43 T 16-09-2016 Spa2297_RS18235 9f26cc5d1ddbe81a64d1cf2e6dbae044 176 Pfam PF03703 Bacterial PH domain 87 165 8.8E-16 T 16-09-2016 IPR005182 Domain of unknown function DUF304 Spa2297_RS18235 9f26cc5d1ddbe81a64d1cf2e6dbae044 176 PANTHER PTHR34473:SF2 22 172 6.9E-43 T 16-09-2016 Spa2297_RS09705 32ac51346bff7347eaf84549fa997c52 415 SUPERFAMILY SSF48239 244 321 1.74E-19 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS09705 32ac51346bff7347eaf84549fa997c52 415 SUPERFAMILY SSF48239 72 166 1.74E-19 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS09705 32ac51346bff7347eaf84549fa997c52 415 Gene3D G3DSA:1.50.10.20 55 175 6.5E-17 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS09705 32ac51346bff7347eaf84549fa997c52 415 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 126 165 1.8E-7 T 16-09-2016 IPR001330 PFTB repeat GO:0003824 Spa2297_RS09705 32ac51346bff7347eaf84549fa997c52 415 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 72 116 1.5 T 16-09-2016 IPR001330 PFTB repeat GO:0003824 Spa2297_RS27850 3ecb0392d91ecdffec90101ffa60d1ec 275 PANTHER PTHR31310 1 271 4.4E-114 T 16-09-2016 Spa2297_RS27850 3ecb0392d91ecdffec90101ffa60d1ec 275 Pfam PF14378 PAP2 superfamily 60 240 7.3E-38 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS27850 3ecb0392d91ecdffec90101ffa60d1ec 275 PANTHER PTHR31310:SF6 1 271 4.4E-114 T 16-09-2016 Spa2297_RS00765 0d7bd05ea3213f7cebb560a99e99277e 335 Pfam PF00355 Rieske [2Fe-2S] domain 51 121 2.0E-11 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS00765 0d7bd05ea3213f7cebb560a99e99277e 335 Gene3D G3DSA:2.102.10.10 51 146 2.5E-16 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS00765 0d7bd05ea3213f7cebb560a99e99277e 335 PANTHER PTHR21266 51 237 4.6E-26 T 16-09-2016 Spa2297_RS00765 0d7bd05ea3213f7cebb560a99e99277e 335 SUPERFAMILY SSF50022 49 146 4.58E-20 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 PANTHER PTHR10000 61 233 1.2E-63 T 16-09-2016 Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 Gene3D G3DSA:3.40.50.1000 77 228 4.7E-49 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 SUPERFAMILY SSF56784 1 222 3.58E-32 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 205 1.7E-60 T 16-09-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 192 2.9E-31 T 16-09-2016 Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 PANTHER PTHR10000:SF10 61 233 1.2E-63 T 16-09-2016 Spa2297_RS17925 1d13af3826ac8e886fd56fa011df3b3e 268 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 194 1.7E-20 T 16-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 SUPERFAMILY SSF53067 134 311 7.77E-39 T 16-09-2016 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 Gene3D G3DSA:3.30.420.150 133 312 4.7E-60 T 16-09-2016 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 PANTHER PTHR30005 1 313 3.1E-152 T 16-09-2016 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 Pfam PF02541 Ppx/GppA phosphatase family 25 308 3.7E-56 T 16-09-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 PANTHER PTHR30005:SF1 1 313 3.1E-152 T 16-09-2016 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 Gene3D G3DSA:3.30.420.40 2 125 1.1E-48 T 16-09-2016 Spa2297_RS13430 a4da8d9a8decd6de5d167e686f2ac278 313 SUPERFAMILY SSF53067 3 124 7.77E-33 T 16-09-2016 Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 Pfam PF00571 CBS domain 9 60 6.5E-11 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 Pfam PF00571 CBS domain 91 144 7.4E-15 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 Gene3D G3DSA:3.20.20.70 8 147 1.6E-32 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 PANTHER PTHR11911 89 155 8.5E-31 T 16-09-2016 Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 PANTHER PTHR11911 9 61 8.5E-31 T 16-09-2016 Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 Pfam PF04972 BON domain 168 212 7.8E-8 T 16-09-2016 IPR007055 BON domain Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 SMART SM00116 97 145 3.6E-11 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 SMART SM00116 16 64 1.9E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 SUPERFAMILY SSF54631 6 146 9.35E-35 T 16-09-2016 Spa2297_RS03930 7dff9e71893d2ad04a5e2127ece376d1 226 PIRSF PIRSF036990 7 225 5.5E-67 T 16-09-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON Spa2297_RS28305 90b43892d5a3d842bb63149af4081b65 124 PANTHER PTHR36221 5 123 3.3E-39 T 16-09-2016 Spa2297_RS28305 90b43892d5a3d842bb63149af4081b65 124 Pfam PF05331 Protein of unknown function (DUF742) 13 123 2.0E-39 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 SUPERFAMILY SSF46689 2 83 1.54E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 Gene3D G3DSA:1.10.10.60 2 59 9.0E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 SUPERFAMILY SSF48498 81 198 5.34E-15 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 PANTHER PTHR30055:SF57 1 196 7.0E-73 T 16-09-2016 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 5.6E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 5.6E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 Gene3D G3DSA:1.10.357.10 60 198 2.1E-43 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.7E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS16800 ffeb0e58cf8afd1b68f86c5cf4cd0ca3 200 PANTHER PTHR30055 1 196 7.0E-73 T 16-09-2016 Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 Gene3D G3DSA:3.40.50.300 11 216 1.0E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 Pfam PF00005 ABC transporter 31 159 3.2E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 PANTHER PTHR24220 17 240 7.7E-80 T 16-09-2016 Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 PANTHER PTHR24220:SF365 17 240 7.7E-80 T 16-09-2016 IPR017875 Aliphatic sulfonates import ATP-binding protein SsuB GO:0005215|GO:0005524|GO:0005886|GO:0006810 Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 SMART SM00382 40 209 1.3E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS01460 188ee20b83d9d03905f5e0d871b3f987 255 SUPERFAMILY SSF52540 16 213 9.25E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PANTHER PTHR24322 9 134 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PANTHER PTHR24322:SF57 150 181 1.2E-47 T 16-09-2016 Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 Gene3D G3DSA:3.40.50.720 5 244 2.6E-64 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PANTHER PTHR24322:SF57 9 134 1.2E-47 T 16-09-2016 Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 Pfam PF00106 short chain dehydrogenase 8 193 4.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 SUPERFAMILY SSF51735 5 244 9.02E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.2E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.2E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.2E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.2E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.2E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.9E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.9E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.9E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32190 4cdf429a679a2d0e8aa6972aab460f51 281 PANTHER PTHR24322 150 181 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Gene3D G3DSA:3.30.930.10 394 469 3.8E-94 T 16-09-2016 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Gene3D G3DSA:3.30.930.10 13 210 3.8E-94 T 16-09-2016 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Hamap MF_01569 Proline--tRNA ligase [proS]. 7 567 36.282 T 16-09-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Gene3D G3DSA:3.40.50.800 472 565 1.1E-19 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 SUPERFAMILY SSF55826 247 401 2.62E-22 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PANTHER PTHR11451:SF3 400 567 7.2E-130 T 16-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PANTHER PTHR11451:SF3 10 250 7.2E-130 T 16-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Gene3D G3DSA:3.90.960.10 245 389 5.3E-21 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PANTHER PTHR11451 400 567 7.2E-130 T 16-09-2016 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PANTHER PTHR11451 10 250 7.2E-130 T 16-09-2016 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 SUPERFAMILY SSF52954 465 565 4.23E-20 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 8 560 3.2E-174 T 16-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 140 148 1.2E-15 T 16-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 150 161 1.2E-15 T 16-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 74 92 1.2E-15 T 16-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 110 121 1.2E-15 T 16-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 461 9.1E-41 T 16-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Pfam PF03129 Anticodon binding domain 478 562 5.5E-14 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 Pfam PF04073 Aminoacyl-tRNA editing domain 262 381 2.2E-27 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 SUPERFAMILY SSF55681 409 480 5.9E-87 T 16-09-2016 Spa2297_RS24130 19c8847295a9af7dcd48fa18118f4281 567 SUPERFAMILY SSF55681 16 243 5.9E-87 T 16-09-2016 Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 SUPERFAMILY SSF52402 2 136 8.29E-26 T 16-09-2016 Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 PANTHER PTHR31964 1 138 3.5E-17 T 16-09-2016 Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 PANTHER PTHR31964:SF42 1 138 3.5E-17 T 16-09-2016 Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 Pfam PF00582 Universal stress protein family 3 135 2.7E-20 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 PRINTS PR01438 Universal stress protein signature 113 135 4.8E-6 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 PRINTS PR01438 Universal stress protein signature 95 107 4.8E-6 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS10405 4813d939f97e482ac1caaf58489cd62a 138 Gene3D G3DSA:3.40.50.620 3 137 4.3E-27 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS25005 1e1d327e9a92ecaea3c0022cacb8a7a7 355 Pfam PF00288 GHMP kinases N terminal domain 105 152 1.9E-9 T 16-09-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spa2297_RS25005 1e1d327e9a92ecaea3c0022cacb8a7a7 355 PANTHER PTHR20861 109 283 5.4E-15 T 16-09-2016 Spa2297_RS25005 1e1d327e9a92ecaea3c0022cacb8a7a7 355 Gene3D G3DSA:3.30.230.10 94 151 9.4E-9 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS25005 1e1d327e9a92ecaea3c0022cacb8a7a7 355 PANTHER PTHR20861:SF5 109 283 5.4E-15 T 16-09-2016 Spa2297_RS25005 1e1d327e9a92ecaea3c0022cacb8a7a7 355 SUPERFAMILY SSF54211 19 180 3.79E-18 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS12560 b7291dd6347b72a0be50290e204c666b 259 Gene3D G3DSA:3.30.230.10 112 245 2.1E-22 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS12560 b7291dd6347b72a0be50290e204c666b 259 PANTHER PTHR10046 113 254 2.4E-62 T 16-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 Spa2297_RS12560 b7291dd6347b72a0be50290e204c666b 259 SUPERFAMILY SSF54211 101 246 3.68E-19 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS12560 b7291dd6347b72a0be50290e204c666b 259 PANTHER PTHR10046:SF48 113 254 2.4E-62 T 16-09-2016 Spa2297_RS12560 b7291dd6347b72a0be50290e204c666b 259 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 153 233 4.1E-7 T 16-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 SUPERFAMILY SSF53067 1 127 4.07E-32 T 16-09-2016 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 35.767 T 16-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 Gene3D G3DSA:3.30.420.40 99 263 7.7E-51 T 16-09-2016 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 Pfam PF03309 Type III pantothenate kinase 2 211 1.3E-68 T 16-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 PANTHER PTHR34265 1 265 7.7E-78 T 16-09-2016 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 6.6E-75 T 16-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 Gene3D G3DSA:3.30.420.40 1 68 1.4E-4 T 16-09-2016 Spa2297_RS18300 43a90a30c1eaa24d322b46b5efa2a0b4 265 SUPERFAMILY SSF53067 129 261 1.12E-36 T 16-09-2016 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 56 69 - T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 Pfam PF00809 Pterin binding enzyme 23 269 9.7E-85 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 PANTHER PTHR20941:SF1 18 288 5.7E-107 T 16-09-2016 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 Gene3D G3DSA:3.20.20.20 18 286 1.8E-102 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 22 283 5.6E-89 T 16-09-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 PANTHER PTHR20941 18 288 5.7E-107 T 16-09-2016 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 22 37 - T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS18210 1fcbda2099d02b037b6a7a95dd16dee1 288 SUPERFAMILY SSF51717 20 284 7.72E-90 T 16-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 6.2E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 6.2E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PANTHER PTHR24322 20 195 5.8E-77 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PANTHER PTHR24322:SF620 20 195 5.8E-77 T 16-09-2016 Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 198 8.0E-4 T 16-09-2016 Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 Gene3D G3DSA:3.40.50.720 16 254 1.0E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 SUPERFAMILY SSF51735 16 254 1.68E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.7E-33 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.7E-33 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.7E-33 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.7E-33 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.7E-33 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS19745 935306bd394968af6d80c778562cc632 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 254 2.1E-55 T 16-09-2016 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PANTHER PTHR26402:SF151 85 237 1.7E-44 T 16-09-2016 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 SUPERFAMILY SSF52172 4 150 4.13E-17 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 209 221 9.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 193 9.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 209 9.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 Gene3D G3DSA:1.10.10.10 178 238 1.2E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 SUPERFAMILY SSF46894 169 238 3.74E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 Pfam PF00196 Bacterial regulatory proteins, luxR family 178 233 9.0E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PANTHER PTHR26402 4 65 1.7E-44 T 16-09-2016 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 Gene3D G3DSA:3.40.50.2300 3 177 1.1E-36 T 16-09-2016 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 SMART SM00421 176 233 2.1E-20 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 SMART SM00448 4 140 1.9E-17 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 Pfam PF00072 Response regulator receiver domain 6 140 2.6E-10 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PANTHER PTHR26402 85 237 1.7E-44 T 16-09-2016 Spa2297_RS13605 f1bbbd07151733696c2155c990b5b551 255 PANTHER PTHR26402:SF151 4 65 1.7E-44 T 16-09-2016 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 SMART SM00458 351 474 9.2E-37 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 Gene3D G3DSA:2.80.10.50 348 472 6.7E-45 T 16-09-2016 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 SUPERFAMILY SSF51445 46 345 7.6E-113 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 PANTHER PTHR31490 39 342 4.6E-136 T 16-09-2016 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 SUPERFAMILY SSF50370 348 472 6.62E-44 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 Pfam PF00331 Glycosyl hydrolase family 10 47 340 2.6E-109 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 Pfam PF00652 Ricin-type beta-trefoil lectin domain 353 471 2.0E-31 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 PRINTS PR00134 Glycosyl hydrolase family 10 signature 119 131 9.3E-17 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 PRINTS PR00134 Glycosyl hydrolase family 10 signature 161 172 9.3E-17 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 PRINTS PR00134 Glycosyl hydrolase family 10 signature 206 217 9.3E-17 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 PRINTS PR00134 Glycosyl hydrolase family 10 signature 236 248 9.3E-17 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 270 280 - T 16-09-2016 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 Gene3D G3DSA:3.20.20.80 48 347 9.5E-116 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS28780 60315049f86995e743e6a52ca84aad94 474 SMART SM00633 88 341 1.7E-147 T 16-09-2016 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 Pfam PF02445 Quinolinate synthetase A protein 54 392 3.4E-106 T 16-09-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 SUPERFAMILY SSF142754 52 393 1.96E-93 T 16-09-2016 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 Hamap MF_00569 Quinolinate synthase A [nadA]. 43 393 57.426 T 16-09-2016 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 PANTHER PTHR30573:SF0 1 393 1.7E-198 T 16-09-2016 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 PANTHER PTHR30573 1 393 1.7E-198 T 16-09-2016 Spa2297_RS08920 d9ebf37b922a363ca690d297889951c9 394 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 47 393 3.2E-100 T 16-09-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.4E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-32 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 1.1E-56 T 16-09-2016 Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PANTHER PTHR24322 9 137 8.2E-76 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PANTHER PTHR24322 153 185 8.2E-76 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 SUPERFAMILY SSF51735 5 247 1.56E-73 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PANTHER PTHR24322:SF503 9 137 8.2E-76 T 16-09-2016 Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 PANTHER PTHR24322:SF503 153 185 8.2E-76 T 16-09-2016 Spa2297_RS32030 ea378ee902ee65210022ba7e4b275da9 248 Gene3D G3DSA:3.40.50.720 5 247 1.5E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 Pfam PF00271 Helicase conserved C-terminal domain 212 321 4.1E-27 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 SUPERFAMILY SSF52540 53 341 4.69E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 Gene3D G3DSA:3.40.50.300 200 351 2.0E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 PANTHER PTHR24031 53 355 1.8E-142 T 16-09-2016 Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 PANTHER PTHR24031 2 34 1.8E-142 T 16-09-2016 Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 PANTHER PTHR24031 779 791 1.8E-142 T 16-09-2016 Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 SMART SM00487 1 204 2.7E-43 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 132 140 - T 16-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 SMART SM00490 240 321 6.2E-32 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 Gene3D G3DSA:3.40.50.300 2 199 2.0E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21795 ae8d1877dfc6decfbc2c7d3c18bfea8f 803 Pfam PF00270 DEAD/DEAH box helicase 2 169 3.3E-47 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SUPERFAMILY SSF90123 662 971 3.14E-71 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SMART SM00382 361 547 1.8E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SMART SM00382 1018 1204 9.0E-20 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 PANTHER PTHR24221 467 1237 1.3E-248 T 16-09-2016 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Gene3D G3DSA:1.20.1560.10 662 978 3.2E-75 T 16-09-2016 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Gene3D G3DSA:1.20.1560.10 9 322 1.6E-68 T 16-09-2016 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Pfam PF00664 ABC transporter transmembrane region 24 291 5.9E-37 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Pfam PF00664 ABC transporter transmembrane region 673 944 1.4E-39 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SUPERFAMILY SSF90123 9 322 9.42E-71 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Pfam PF00005 ABC transporter 1010 1158 8.9E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Pfam PF00005 ABC transporter 352 501 1.4E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SUPERFAMILY SSF52540 981 1227 2.61E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 SUPERFAMILY SSF52540 329 568 1.09E-86 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Gene3D G3DSA:3.40.50.300 990 1222 1.7E-77 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11690 6f4593535d673fc1a949b01dda68e708 1242 Gene3D G3DSA:3.40.50.300 336 564 1.2E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 SMART SM00448 7 120 7.0E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 PANTHER PTHR26402:SF583 7 218 6.7E-123 T 16-09-2016 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 SUPERFAMILY SSF52172 6 128 2.85E-32 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 SMART SM00421 154 211 1.0E-24 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 Gene3D G3DSA:3.40.50.2300 6 161 4.9E-37 T 16-09-2016 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 SUPERFAMILY SSF46894 154 218 3.13E-21 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 PANTHER PTHR26402 7 218 6.7E-123 T 16-09-2016 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 Pfam PF00072 Response regulator receiver domain 9 120 5.3E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 6.1E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 5.5E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 5.5E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 5.5E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24485 5238c84a05954a2b6c5de843677075c9 219 Gene3D G3DSA:1.10.10.10 162 217 5.3E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 PANTHER PTHR24362:SF247 89 351 1.2E-92 T 16-09-2016 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 SMART SM00220 100 354 7.0E-60 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 Gene3D G3DSA:3.30.200.20 93 169 2.4E-22 T 16-09-2016 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 Pfam PF00069 Protein kinase domain 100 349 2.7E-46 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 Gene3D G3DSA:1.10.510.10 170 350 5.1E-48 T 16-09-2016 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 PANTHER PTHR24362 89 351 1.2E-92 T 16-09-2016 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 106 129 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 222 234 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS20160 85eb9d9398ad117a0213c27c223dd030 591 SUPERFAMILY SSF56112 84 352 1.62E-69 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 SUPERFAMILY SSF46894 139 210 5.44E-21 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 SMART SM00448 7 121 6.1E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 SUPERFAMILY SSF52172 6 141 7.83E-28 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 SMART SM00421 147 204 4.5E-23 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 PANTHER PTHR26402:SF151 7 210 2.3E-67 T 16-09-2016 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 9.0E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 Gene3D G3DSA:3.40.50.2300 6 152 9.4E-32 T 16-09-2016 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 PANTHER PTHR26402 7 210 2.3E-67 T 16-09-2016 Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 Gene3D G3DSA:1.10.10.10 153 210 1.4E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04035 bbc7f39b626d8dd430b4c758b8610cb8 212 Pfam PF00072 Response regulator receiver domain 10 121 1.0E-21 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 16-09-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 SMART SM01004 7 329 2.0E-210 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 1.6E-54 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 327 8.5E-136 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PIRSF PIRSF001415 1 330 3.5E-146 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 PANTHER PTHR11458 1 330 7.2E-169 T 16-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 Gene3D G3DSA:3.20.20.70 6 329 9.7E-141 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS18610 a3c2ef1e94a2662500c1d678c74672df 330 SUPERFAMILY SSF51569 5 329 8.2E-129 T 16-09-2016 Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 Pfam PF13439 Glycosyltransferase Family 4 21 179 3.3E-26 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 Pfam PF13692 Glycosyl transferases group 1 220 363 5.0E-34 T 16-09-2016 Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 PANTHER PTHR12526 9 401 4.5E-82 T 16-09-2016 Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 SUPERFAMILY SSF53756 15 401 1.33E-81 T 16-09-2016 Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 PANTHER PTHR12526:SF374 9 401 4.5E-82 T 16-09-2016 Spa2297_RS11445 37a144a572fa394e68f845c6326516cc 453 Gene3D G3DSA:3.40.50.2000 170 377 1.1E-34 T 16-09-2016 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 PANTHER PTHR30154:SF26 1 147 2.9E-86 T 16-09-2016 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 SMART SM00344 8 115 5.8E-33 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 Gene3D G3DSA:3.30.70.920 62 140 2.3E-18 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 SUPERFAMILY SSF54909 69 148 5.5E-15 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 PANTHER PTHR30154 1 147 2.9E-86 T 16-09-2016 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 SUPERFAMILY SSF46785 8 68 1.22E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 3.4E-15 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.8E-13 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.8E-13 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.8E-13 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 Pfam PF13404 AsnC-type helix-turn-helix domain 9 49 2.7E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04420 dfee72b237aacfa0761d3d6e935ca9a9 167 Gene3D G3DSA:1.10.10.10 7 59 1.6E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 PANTHER PTHR23508:SF17 1 477 1.2E-283 T 16-09-2016 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 SUPERFAMILY SSF103473 35 461 1.57E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 ProSitePatterns PS00217 Sugar transport proteins signature 2. 153 178 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 ProSitePatterns PS00216 Sugar transport proteins signature 1. 329 346 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 Pfam PF00083 Sugar (and other) transporter 48 462 1.3E-44 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 Gene3D G3DSA:1.20.1250.20 41 247 8.6E-28 T 16-09-2016 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 Gene3D G3DSA:1.20.1250.20 272 458 3.5E-23 T 16-09-2016 Spa2297_RS01730 5e5248ea853d2430d34abf255be39589 495 PANTHER PTHR23508 1 477 1.2E-283 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 Pfam PF07687 Peptidase dimerisation domain 210 303 2.7E-6 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 PANTHER PTHR11014:SF63 26 408 5.5E-134 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 SUPERFAMILY SSF55031 206 319 8.37E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 Gene3D G3DSA:3.30.70.360 205 320 5.6E-29 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 Pfam PF01546 Peptidase family M20/M25/M40 92 405 2.5E-26 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 398 9.3E-99 T 16-09-2016 IPR017439 Amidohydrolase GO:0016787 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 Gene3D G3DSA:3.40.630.10 321 407 1.8E-86 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 Gene3D G3DSA:3.40.630.10 21 201 1.8E-86 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 SUPERFAMILY SSF53187 321 406 3.11E-63 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 SUPERFAMILY SSF53187 21 220 3.11E-63 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 PANTHER PTHR11014 26 408 5.5E-134 T 16-09-2016 Spa2297_RS20665 5748a1004d53183772e42b8e19aa9990 412 PIRSF PIRSF005962 17 410 9.0E-95 T 16-09-2016 IPR017439 Amidohydrolase GO:0016787 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Gene3D G3DSA:3.40.1390.20 205 342 1.5E-24 T 16-09-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 SUPERFAMILY SSF53659 365 686 4.52E-95 T 16-09-2016 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Pfam PF07085 DRTGG domain 209 319 9.2E-21 T 16-09-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Gene3D G3DSA:3.40.50.300 3 204 2.9E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 1.2E-121 T 16-09-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 PANTHER PTHR23406:SF3 154 688 6.0E-56 T 16-09-2016 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 SUPERFAMILY SSF52540 4 215 5.84E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 PANTHER PTHR23406 154 688 6.0E-56 T 16-09-2016 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 SUPERFAMILY SSF75138 204 322 4.71E-18 T 16-09-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Gene3D G3DSA:3.40.50.10750 501 659 3.4E-67 T 16-09-2016 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 PIRSF PIRSF006107 1 691 1.1E-181 T 16-09-2016 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Pfam PF13500 AAA domain 3 205 2.7E-19 T 16-09-2016 Spa2297_RS22935 2edbd80622ed7bd0ec006a380eba02b2 697 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 1.7E-126 T 16-09-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 Spa2297_RS32015 1689dfbc400e990c19edf454ebc54c1a 407 PANTHER PTHR22935 43 358 3.5E-62 T 16-09-2016 Spa2297_RS32015 1689dfbc400e990c19edf454ebc54c1a 407 Pfam PF00144 Beta-lactamase 49 360 2.2E-56 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS32015 1689dfbc400e990c19edf454ebc54c1a 407 Gene3D G3DSA:3.40.710.10 43 368 2.4E-83 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS32015 1689dfbc400e990c19edf454ebc54c1a 407 SUPERFAMILY SSF56601 51 364 1.65E-80 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS21950 8fb9a0818b4cc53fc509da127cdf9f4b 251 PANTHER PTHR38074 1 251 1.3E-87 T 16-09-2016 Spa2297_RS21950 8fb9a0818b4cc53fc509da127cdf9f4b 251 SUPERFAMILY SSF51219 21 224 3.4E-39 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS21950 8fb9a0818b4cc53fc509da127cdf9f4b 251 Pfam PF01987 Mitochondrial biogenesis AIM24 22 215 1.2E-27 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS21950 8fb9a0818b4cc53fc509da127cdf9f4b 251 PANTHER PTHR38074:SF1 1 251 1.3E-87 T 16-09-2016 Spa2297_RS21950 8fb9a0818b4cc53fc509da127cdf9f4b 251 Gene3D G3DSA:3.60.160.10 10 220 1.3E-33 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 16-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 Pfam PF00682 HMGL-like 4 260 2.0E-65 T 16-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 PANTHER PTHR10277 2 371 2.6E-113 T 16-09-2016 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 PANTHER PTHR10277:SF9 2 371 2.6E-113 T 16-09-2016 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 197 210 - T 16-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 Gene3D G3DSA:3.20.20.70 2 341 2.3E-102 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS02900 9e7c192d79753f2e1fd25e49a1c53c55 390 SUPERFAMILY SSF51569 2 289 2.93E-70 T 16-09-2016 Spa2297_RS27655 602e4b1752f68bc8708c336975921ce1 409 SUPERFAMILY SSF56601 17 401 5.63E-93 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS27655 602e4b1752f68bc8708c336975921ce1 409 Pfam PF00144 Beta-lactamase 26 397 2.7E-77 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS27655 602e4b1752f68bc8708c336975921ce1 409 PANTHER PTHR22935 5 407 2.0E-104 T 16-09-2016 Spa2297_RS27655 602e4b1752f68bc8708c336975921ce1 409 PANTHER PTHR22935:SF77 5 407 2.0E-104 T 16-09-2016 Spa2297_RS27655 602e4b1752f68bc8708c336975921ce1 409 Gene3D G3DSA:3.40.710.10 12 403 1.1E-86 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS26470 e5d229db22a4891d2f03cfddfe93aad1 269 Pfam PF01337 Barstar (barnase inhibitor) 176 261 2.9E-14 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS26470 e5d229db22a4891d2f03cfddfe93aad1 269 Gene3D G3DSA:3.30.370.10 174 260 1.6E-13 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS26470 e5d229db22a4891d2f03cfddfe93aad1 269 SUPERFAMILY SSF52038 174 262 1.11E-12 T 16-09-2016 IPR000468 Barstar (barnase inhibitor) Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 Gene3D G3DSA:1.10.443.10 172 336 8.1E-35 T 16-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 Pfam PF00589 Phage integrase family 169 331 9.6E-22 T 16-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 SUPERFAMILY SSF56349 60 334 1.27E-50 T 16-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 Gene3D G3DSA:1.10.150.130 60 156 7.2E-10 T 16-09-2016 IPR023109 Integrase/recombinase, N-terminal Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 PANTHER PTHR30349:SF20 75 361 2.5E-35 T 16-09-2016 Spa2297_RS09100 a802d81d2a3ca50775baddfc920e8043 374 PANTHER PTHR30349 75 361 2.5E-35 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SUPERFAMILY SSF55785 33 146 5.59E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Pfam PF08448 PAS fold 165 276 9.0E-26 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SMART SM00091 28 95 7.7E-4 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SMART SM00091 158 224 1.1E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 PANTHER PTHR21021:SF19 584 725 9.2E-60 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 PANTHER PTHR21021:SF19 440 563 9.2E-60 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SUPERFAMILY SSF55785 159 272 1.19E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Gene3D G3DSA:3.30.450.20 32 147 5.2E-14 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SUPERFAMILY SSF55874 757 842 1.57E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Pfam PF13426 PAS domain 42 147 0.42 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Gene3D G3DSA:3.30.450.40 291 459 6.5E-37 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 PANTHER PTHR21021 584 725 9.2E-60 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SMART SM00331 479 716 2.0E-44 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Gene3D G3DSA:3.30.450.20 158 274 8.8E-19 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SUPERFAMILY SSF81606 495 717 5.23E-10 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 512 717 5.3E-52 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SMART SM00065 303 461 3.4E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 SUPERFAMILY SSF55781 286 468 6.32E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 PANTHER PTHR21021 440 563 9.2E-60 T 16-09-2016 Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 149 1.6E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 161 280 1.2E-7 T 16-09-2016 IPR000014 PAS domain Spa2297_RS21520 a7606b0e375832327c35e907248ece60 860 Pfam PF01590 GAF domain 380 451 3.7E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 PIRSF PIRSF006232 20 302 9.3E-79 T 16-09-2016 IPR012093 Pirin Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 SUPERFAMILY SSF51182 36 302 5.28E-66 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 Gene3D G3DSA:2.60.120.10 28 265 3.1E-59 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 PANTHER PTHR13903 1 309 4.5E-167 T 16-09-2016 IPR012093 Pirin Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 Pfam PF02678 Pirin 41 141 4.8E-24 T 16-09-2016 IPR003829 Pirin, N-terminal domain Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 Pfam PF05726 Pirin C-terminal cupin domain 193 291 2.8E-19 T 16-09-2016 IPR008778 Pirin, C-terminal domain Spa2297_RS29195 1fd21e446f67085f12fc142912a51e03 321 PANTHER PTHR13903:SF4 1 309 4.5E-167 T 16-09-2016 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 SUPERFAMILY SSF56003 149 765 4.97E-120 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Gene3D G3DSA:3.30.365.10 606 766 7.7E-36 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 43 147 1.6E-28 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Gene3D G3DSA:3.30.365.10 461 598 9.9E-22 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Gene3D G3DSA:3.90.1170.50 27 147 9.0E-40 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 SUPERFAMILY SSF54665 27 149 7.98E-39 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 PANTHER PTHR11908 28 441 6.0E-182 T 16-09-2016 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 PANTHER PTHR11908 458 766 6.0E-182 T 16-09-2016 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Gene3D G3DSA:3.30.365.10 279 411 5.0E-40 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 711 9.1E-106 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 SMART SM01008 42 148 1.1E-44 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS12695 836694cc307071bb207d7c768cea0e59 772 Gene3D G3DSA:3.30.365.10 177 278 5.2E-17 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 SUPERFAMILY SSF53474 246 332 1.91E-7 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 SUPERFAMILY SSF53474 145 161 1.91E-7 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 Pfam PF06259 Alpha/beta hydrolase 157 330 2.1E-63 T 16-09-2016 IPR010427 Protein of unknown function DUF1023 Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 Gene3D G3DSA:3.40.50.1820 201 202 5.8E-8 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 Gene3D G3DSA:3.40.50.1820 144 166 5.8E-8 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09995 d42875ba1a7ff05a6b547eb526d7780e 405 Gene3D G3DSA:3.40.50.1820 241 306 5.8E-8 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28100 e2b9c7743220c3ba24cac58e3611194e 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 244 2.0E-39 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS28100 e2b9c7743220c3ba24cac58e3611194e 251 SUPERFAMILY SSF52096 4 243 3.52E-67 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS28100 e2b9c7743220c3ba24cac58e3611194e 251 PANTHER PTHR11941 1 243 1.9E-65 T 16-09-2016 Spa2297_RS28100 e2b9c7743220c3ba24cac58e3611194e 251 Gene3D G3DSA:3.90.226.10 4 240 5.6E-62 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS07935 d12691874a1a4a7ed9a5acfa5ce14389 192 Gene3D G3DSA:2.60.60.30 20 181 3.9E-46 T 16-09-2016 Spa2297_RS07935 d12691874a1a4a7ed9a5acfa5ce14389 192 PANTHER PTHR32097:SF7 2 188 1.0E-78 T 16-09-2016 Spa2297_RS07935 d12691874a1a4a7ed9a5acfa5ce14389 192 PANTHER PTHR32097 2 188 1.0E-78 T 16-09-2016 Spa2297_RS07935 d12691874a1a4a7ed9a5acfa5ce14389 192 Pfam PF02342 TerD domain 2 179 4.1E-43 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 Pfam PF07676 WD40-like Beta Propeller Repeat 190 203 0.15 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 SUPERFAMILY SSF53474 384 640 4.02E-56 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 Pfam PF00326 Prolyl oligopeptidase family 437 642 2.0E-42 T 16-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 Gene3D G3DSA:3.40.50.1820 346 638 1.3E-60 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 PANTHER PTHR11731 10 654 4.2E-160 T 16-09-2016 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 PANTHER PTHR11731:SF75 10 654 4.2E-160 T 16-09-2016 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 Gene3D G3DSA:2.130.10.10 49 268 1.9E-9 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 SUPERFAMILY SSF82171 77 115 5.89E-11 T 16-09-2016 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 SUPERFAMILY SSF82171 156 269 5.89E-11 T 16-09-2016 Spa2297_RS27010 2a4a8d72082d66ee2b688a777d3a29c5 655 SUPERFAMILY SSF82171 311 369 5.89E-11 T 16-09-2016 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 SMART SM00829 10 343 8.8E-6 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 SUPERFAMILY SSF50129 1 160 2.89E-55 T 16-09-2016 IPR011032 GroES-like Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 SUPERFAMILY SSF51735 140 308 2.54E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 3.5E-29 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 Gene3D G3DSA:3.40.50.720 173 287 6.6E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 Gene3D G3DSA:3.90.180.10 1 172 1.0E-53 T 16-09-2016 IPR011032 GroES-like Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 PANTHER PTHR11695 12 354 2.0E-133 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 Pfam PF00107 Zinc-binding dehydrogenase 178 292 7.1E-26 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS03940 8e8ff839b45347aede117e482321fb28 355 PANTHER PTHR11695:SF559 12 354 2.0E-133 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Pfam PF09369 Domain of unknown function (DUF1998) 1728 1818 8.7E-9 T 16-09-2016 IPR018973 DEAD/DEAH-box helicase, putative Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Pfam PF00270 DEAD/DEAH box helicase 79 256 1.7E-13 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Gene3D G3DSA:3.40.50.300 1113 1207 9.3E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Gene3D G3DSA:3.40.50.300 678 699 9.3E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 SMART SM00490 1109 1194 1.2E-14 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031:SF249 75 275 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Pfam PF00271 Helicase conserved C-terminal domain 1119 1193 9.4E-10 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031 292 384 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 SUPERFAMILY SSF52540 74 277 4.84E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031 1125 1220 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031 75 275 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 SUPERFAMILY SSF52540 1108 1215 1.95E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 SUPERFAMILY SSF52540 96 155 1.95E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 SMART SM00487 72 301 1.7E-10 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031:SF249 1125 1220 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 PANTHER PTHR24031:SF249 292 384 4.0E-34 T 16-09-2016 Spa2297_RS22525 cc17e51dbbc3530d85c6023391c22152 2425 Gene3D G3DSA:3.40.50.300 73 276 3.7E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05505 c2fd18c6e8f3d088370c0a1bfc47146f 496 PIRSF PIRSF006060 34 493 1.9E-93 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS05505 c2fd18c6e8f3d088370c0a1bfc47146f 496 TIGRFAM TIGR00909 2A0306: amino acid transporter 46 476 2.0E-190 T 16-09-2016 IPR004758 Amino acid transporter Spa2297_RS05505 c2fd18c6e8f3d088370c0a1bfc47146f 496 PANTHER PTHR11785:SF328 1 496 9.9E-301 T 16-09-2016 Spa2297_RS05505 c2fd18c6e8f3d088370c0a1bfc47146f 496 PANTHER PTHR11785 1 496 9.9E-301 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS05505 c2fd18c6e8f3d088370c0a1bfc47146f 496 Pfam PF13520 Amino acid permease 50 455 1.9E-57 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 Gene3D G3DSA:3.30.70.1450 146 212 1.2E-6 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 Pfam PF02080 TrkA-C domain 150 213 1.6E-12 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PANTHER PTHR16254:SF23 1 158 1.4E-105 T 16-09-2016 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.9E-9 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.9E-9 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.9E-9 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.9E-9 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 SUPERFAMILY SSF51735 2 140 1.28E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 PANTHER PTHR16254 1 158 1.4E-105 T 16-09-2016 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 SUPERFAMILY SSF116726 141 211 7.32E-9 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 Gene3D G3DSA:3.40.50.720 2 140 3.8E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24900 fecb4791b524538426a9185796fb5307 223 Pfam PF02254 TrkA-N domain 3 116 7.6E-26 T 16-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 Pfam PF13560 Helix-turn-helix domain 15 75 1.8E-9 T 16-09-2016 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 PANTHER PTHR10245 7 286 3.2E-131 T 16-09-2016 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 PANTHER PTHR10245:SF20 7 286 3.2E-131 T 16-09-2016 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 SMART SM00530 18 73 2.8E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 SUPERFAMILY SSF47413 14 71 1.04E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS08005 711ee40db31b5c95f666c68269164a01 286 Gene3D G3DSA:1.10.260.40 12 69 2.3E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31545 5d6e0043c14479c6ea910d8b6fa8c6f4 90 SUPERFAMILY SSF46785 10 89 5.71E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31545 5d6e0043c14479c6ea910d8b6fa8c6f4 90 Gene3D G3DSA:1.10.10.10 9 88 5.2E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31545 5d6e0043c14479c6ea910d8b6fa8c6f4 90 Pfam PF11625 Protein of unknown function (DUF3253) 11 88 3.3E-31 T 16-09-2016 IPR021660 Protein of unknown function DUF3253 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 Gene3D G3DSA:3.30.360.10 162 317 2.3E-74 T 16-09-2016 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 Gene3D G3DSA:3.40.50.720 2 161 1.9E-78 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PANTHER PTHR10836 2 336 5.6E-220 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PIRSF PIRSF000149 1 335 5.4E-138 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 SUPERFAMILY SSF55347 153 316 2.92E-70 T 16-09-2016 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 315 2.4E-69 T 16-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 SMART SM00846 3 153 1.8E-97 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 1.4E-62 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 7.0E-40 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 7.0E-40 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 7.0E-40 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 7.0E-40 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 7.0E-40 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 SUPERFAMILY SSF51735 2 152 4.72E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 PANTHER PTHR10836:SF50 2 336 5.6E-220 T 16-09-2016 Spa2297_RS07850 fb7d548b03a334ca4cbe3d117b54bb4b 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 3.1E-140 T 16-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 251 262 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 135 150 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 269 296 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 318 327 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 327 338 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 171 193 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 297 312 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 72 83 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PRINTS PR00359 B-class P450 signature 118 134 9.2E-53 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 320 329 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 SUPERFAMILY SSF48264 6 378 6.02E-91 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 PANTHER PTHR11712 9 377 1.1E-95 T 16-09-2016 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 Pfam PF00067 Cytochrome P450 188 348 1.0E-22 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS17095 1042264ac9fcc122ff80b8b49af57d7a 379 Gene3D G3DSA:1.10.630.10 3 378 3.1E-120 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Gene3D G3DSA:2.130.10.130 249 375 1.2E-16 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Gene3D G3DSA:2.130.10.130 379 592 5.5E-8 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Gene3D G3DSA:2.130.10.130 667 731 5.5E-8 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SUPERFAMILY SSF69318 246 582 2.09E-13 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Pfam PF00089 Trypsin 42 243 1.7E-20 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Gene3D G3DSA:2.40.10.10 131 246 6.9E-11 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 PANTHER PTHR24278 5 732 2.4E-301 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SMART SM00191 307 365 0.27 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SMART SM00191 239 298 60.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SMART SM00191 381 438 2.6 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SMART SM00191 443 504 32.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SUPERFAMILY SSF50494 29 246 3.06E-26 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Pfam PF01839 FG-GAP repeat 311 349 2.9E-7 T 16-09-2016 IPR013517 FG-GAP repeat Reactome: REACT_13552 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 PANTHER PTHR24278:SF22 5 732 2.4E-301 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 SMART SM00020 30 243 3.5E-7 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 Gene3D G3DSA:2.40.10.10 57 130 7.2E-8 T 16-09-2016 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 190 202 1.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 117 131 1.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS28275 240007fbcc69b45f0963a279f6cbc721 732 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 60 75 1.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS09345 00bf95cf442ff0338a6055f095fcdbb0 148 PANTHER PTHR34309:SF2 1 142 1.5E-76 T 16-09-2016 Spa2297_RS09345 00bf95cf442ff0338a6055f095fcdbb0 148 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 125 9.4E-13 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS09345 00bf95cf442ff0338a6055f095fcdbb0 148 SUPERFAMILY SSF54593 9 136 1.33E-24 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS09345 00bf95cf442ff0338a6055f095fcdbb0 148 Gene3D G3DSA:3.10.180.10 9 127 3.1E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS09345 00bf95cf442ff0338a6055f095fcdbb0 148 PANTHER PTHR34309 1 142 1.5E-76 T 16-09-2016 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 Pfam PF01411 tRNA synthetases class II (A) 6 388 1.3E-79 T 16-09-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PRINTS PR00980 Alanyl-tRNA synthetase signature 217 230 7.6E-22 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PRINTS PR00980 Alanyl-tRNA synthetase signature 260 276 7.6E-22 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PRINTS PR00980 Alanyl-tRNA synthetase signature 190 201 7.6E-22 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PRINTS PR00980 Alanyl-tRNA synthetase signature 70 81 7.6E-22 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PRINTS PR00980 Alanyl-tRNA synthetase signature 284 297 7.6E-22 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 Gene3D G3DSA:3.30.930.10 1 232 4.1E-64 T 16-09-2016 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PANTHER PTHR11777 1 382 4.3E-263 T 16-09-2016 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 SUPERFAMILY SSF55681 2 236 1.09E-63 T 16-09-2016 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 SUPERFAMILY SSF101353 237 388 1.12E-29 T 16-09-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS00850 ee23fc457a3aa9789f7f6371c541c1ba 401 PANTHER PTHR11777:SF11 1 382 4.3E-263 T 16-09-2016 Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 SUPERFAMILY SSF46894 17 86 9.64E-5 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 SUPERFAMILY SSF48452 113 223 5.5E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 Pfam PF00486 Transcriptional regulatory protein, C terminal 20 85 1.2E-4 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 SMART SM01043 116 229 4.3E-10 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 Pfam PF03704 Bacterial transcriptional activator domain 116 216 1.2E-7 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS18700 6891da709ac927b26407f4a8de6ab11c 476 Gene3D G3DSA:1.10.10.10 15 85 6.1E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 Pfam PF00583 Acetyltransferase (GNAT) family 46 122 2.7E-19 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 141 8.2E-32 T 16-09-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 SUPERFAMILY SSF55729 5 144 1.36E-32 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 Gene3D G3DSA:3.40.630.30 2 143 2.7E-34 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 PANTHER PTHR23091:SF264 1 143 1.5E-40 T 16-09-2016 Spa2297_RS20030 2602eb82b852b0ea5646fe3882b681d0 174 PANTHER PTHR23091 1 143 1.5E-40 T 16-09-2016 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 Pfam PF05025 RbsD / FucU transport protein family 2 127 1.8E-35 T 16-09-2016 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 PANTHER PTHR37831 2 129 9.4E-61 T 16-09-2016 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 SUPERFAMILY SSF102546 2 129 1.11E-34 T 16-09-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 Gene3D G3DSA:3.40.1650.10 4 129 1.7E-22 T 16-09-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 28.027 T 16-09-2016 IPR023064 D-ribose pyranase GO:0016872 UniPathway: UPA00916 Spa2297_RS11620 3c9684e817d13bcd67120cb8d2217bab 129 PANTHER PTHR37831:SF1 2 129 9.4E-61 T 16-09-2016 Spa2297_RS12880 16b7144362521067f29343c5f5721c46 287 Gene3D G3DSA:1.10.3720.10 17 275 1.4E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12880 16b7144362521067f29343c5f5721c46 287 PANTHER PTHR32243:SF9 10 287 8.1E-147 T 16-09-2016 Spa2297_RS12880 16b7144362521067f29343c5f5721c46 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 272 2.3E-13 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12880 16b7144362521067f29343c5f5721c46 287 SUPERFAMILY SSF161098 20 287 5.33E-67 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12880 16b7144362521067f29343c5f5721c46 287 PANTHER PTHR32243 10 287 8.1E-147 T 16-09-2016 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 237 6.1E-34 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Gene3D G3DSA:1.10.10.10 93 146 3.4E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PANTHER PTHR30385:SF4 13 236 1.9E-95 T 16-09-2016 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Gene3D G3DSA:1.10.601.10 14 92 2.5E-25 T 16-09-2016 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 47 60 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 SUPERFAMILY SSF88659 174 238 7.1E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Pfam PF04545 Sigma-70, region 4 189 236 7.9E-16 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Pfam PF04542 Sigma-70 region 2 23 92 5.8E-19 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Gene3D G3DSA:1.10.10.10 179 237 2.0E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 17 238 3.9E-89 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 SUPERFAMILY SSF88946 8 93 4.19E-30 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 Pfam PF04539 Sigma-70 region 3 102 165 1.5E-15 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 SUPERFAMILY SSF88659 96 169 7.85E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PRINTS PR00046 Major sigma-70 factor signature 224 235 2.5E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PRINTS PR00046 Major sigma-70 factor signature 47 60 2.5E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PRINTS PR00046 Major sigma-70 factor signature 209 224 2.5E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PRINTS PR00046 Major sigma-70 factor signature 192 204 2.5E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15980 43e8e6592de017c6c46ea534d0a629c3 243 PANTHER PTHR30385 13 236 1.9E-95 T 16-09-2016 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 SUPERFAMILY SSF52518 27 208 2.74E-61 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 SUPERFAMILY SSF52518 395 609 4.47E-66 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 30 603 6.7E-232 T 16-09-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 PANTHER PTHR18968:SF116 8 606 0.0 T 16-09-2016 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Gene3D G3DSA:3.40.50.970 381 595 1.5E-75 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Gene3D G3DSA:3.40.50.970 28 205 6.8E-73 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 219 354 5.9E-48 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 455 474 - T 16-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 PANTHER PTHR18968 8 606 0.0 T 16-09-2016 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 SUPERFAMILY SSF52467 211 386 1.73E-62 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 30 195 5.3E-56 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 418 579 1.1E-46 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS23330 ea73501c1c7fc83a6f1c1bcba57494b0 617 Gene3D G3DSA:3.40.50.1220 212 380 3.7E-68 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 Gene3D G3DSA:1.20.1250.20 275 452 4.2E-21 T 16-09-2016 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 Gene3D G3DSA:1.20.1250.20 20 204 4.1E-34 T 16-09-2016 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 SUPERFAMILY SSF103473 20 212 7.32E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 SUPERFAMILY SSF103473 262 456 7.32E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 Pfam PF07690 Major Facilitator Superfamily 29 295 2.1E-27 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 PANTHER PTHR23508 268 484 5.9E-192 T 16-09-2016 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 PANTHER PTHR23508 11 229 5.9E-192 T 16-09-2016 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 PANTHER PTHR23508:SF3 268 484 5.9E-192 T 16-09-2016 Spa2297_RS01480 bf1f04a60e439139c51474577fb3d285 489 PANTHER PTHR23508:SF3 11 229 5.9E-192 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PANTHER PTHR22912:SF159 3 314 1.0E-122 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PANTHER PTHR22912 3 314 1.0E-122 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 17 298 7.7E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 2.5E-11 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.5E-11 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.5E-11 T 16-09-2016 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 Gene3D G3DSA:3.50.50.60 139 240 2.5E-34 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 Gene3D G3DSA:3.50.50.60 16 138 1.0E-34 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 Gene3D G3DSA:3.50.50.60 263 310 1.0E-34 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 8.3E-14 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 8.3E-14 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 18 40 8.3E-14 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 8.3E-14 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS04335 474d5913e3d7eff9de0c8dde5f9e26a1 321 SUPERFAMILY SSF51905 16 311 4.61E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 Gene3D G3DSA:2.60.60.30 23 159 2.0E-26 T 16-09-2016 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 Gene3D G3DSA:2.60.60.30 238 390 9.1E-50 T 16-09-2016 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 PANTHER PTHR32097 5 396 6.6E-238 T 16-09-2016 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 Pfam PF02342 TerD domain 220 388 7.0E-40 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 Pfam PF02342 TerD domain 23 161 6.4E-27 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS07595 8781c2e561f314f010f80a231a661961 402 PANTHER PTHR32097:SF7 5 396 6.6E-238 T 16-09-2016 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 Pfam PF00005 ABC transporter 22 164 2.0E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 PANTHER PTHR24220:SF429 3 243 9.9E-98 T 16-09-2016 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 PANTHER PTHR24220:SF429 276 313 9.9E-98 T 16-09-2016 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 PANTHER PTHR24220 3 243 9.9E-98 T 16-09-2016 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 308 1.1E-96 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 PANTHER PTHR24220 276 313 9.9E-98 T 16-09-2016 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 SUPERFAMILY SSF52540 10 226 8.5E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 Pfam PF13732 Domain of unknown function (DUF4162) 219 306 2.7E-10 T 16-09-2016 IPR025302 Domain of unknown function DUF4162 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 Gene3D G3DSA:3.40.50.300 1 226 8.2E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS02640 8d13ff0ab3334ff6b106ca47a2e44c58 327 SMART SM00382 30 213 1.3E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27735 20935088ec7a15fcbbe274011441a4b8 194 PANTHER PTHR36492:SF1 6 185 1.0E-63 T 16-09-2016 Spa2297_RS27735 20935088ec7a15fcbbe274011441a4b8 194 Gene3D G3DSA:3.60.21.10 10 172 1.9E-13 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS27735 20935088ec7a15fcbbe274011441a4b8 194 PANTHER PTHR36492 6 185 1.0E-63 T 16-09-2016 Spa2297_RS27735 20935088ec7a15fcbbe274011441a4b8 194 SUPERFAMILY SSF56300 10 172 1.2E-14 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS00265 c0bdc3dcb49851c17b38caa873d8b461 344 PANTHER PTHR32196 6 344 1.9E-84 T 16-09-2016 Spa2297_RS00265 c0bdc3dcb49851c17b38caa873d8b461 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 331 7.1E-46 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS00265 c0bdc3dcb49851c17b38caa873d8b461 344 PANTHER PTHR32196:SF21 6 344 1.9E-84 T 16-09-2016 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 475 46.308 T 16-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 PANTHER PTHR11907 20 487 9.9E-231 T 16-09-2016 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 SUPERFAMILY SSF53271 268 482 7.08E-68 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 Gene3D G3DSA:3.60.20.10 23 274 9.8E-67 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 PIRSF PIRSF000485 19 485 7.7E-160 T 16-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 PANTHER PTHR11907:SF0 20 487 9.9E-231 T 16-09-2016 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 Gene3D G3DSA:3.40.50.2020 290 456 2.6E-44 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 SUPERFAMILY SSF56235 23 286 1.2E-62 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 2.4E-156 T 16-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 Pfam PF13522 Glutamine amidotransferase domain 85 227 1.1E-15 T 16-09-2016 Spa2297_RS15765 7bff3837a6174fceac8e167c9c75f926 508 Pfam PF00156 Phosphoribosyl transferase domain 300 403 5.3E-7 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 Gene3D G3DSA:3.40.50.10540 303 376 1.3E-97 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 Gene3D G3DSA:3.40.50.10540 13 218 1.3E-97 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 SUPERFAMILY SSF89796 14 377 1.7E-116 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 PANTHER PTHR24023:SF545 18 25 6.1E-117 T 16-09-2016 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 PANTHER PTHR24023:SF545 55 376 6.1E-117 T 16-09-2016 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 PANTHER PTHR24023 18 25 6.1E-117 T 16-09-2016 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 PANTHER PTHR24023 55 376 6.1E-117 T 16-09-2016 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 Pfam PF02515 CoA-transferase family III 16 365 3.1E-87 T 16-09-2016 IPR003673 CoA-transferase family III GO:0003824 Spa2297_RS28025 f32fe35a8ba63c5376b5be2f10d933c9 394 Gene3D G3DSA:3.30.1540.10 234 302 1.8E-11 T 16-09-2016 Spa2297_RS03195 fea3f291451a5f072bb2caffaea21dfc 538 Pfam PF07905 Purine catabolism regulatory protein-like family 18 139 1.8E-36 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS03195 fea3f291451a5f072bb2caffaea21dfc 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 473 531 7.4E-17 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS03195 fea3f291451a5f072bb2caffaea21dfc 538 PANTHER PTHR33744 16 538 2.0E-206 T 16-09-2016 Spa2297_RS03195 fea3f291451a5f072bb2caffaea21dfc 538 PANTHER PTHR33744:SF5 16 538 2.0E-206 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 PANTHER PTHR10516 221 332 1.7E-111 T 16-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 PANTHER PTHR10516 95 186 1.7E-111 T 16-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 PANTHER PTHR10516:SF320 221 332 1.7E-111 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 PANTHER PTHR10516:SF320 95 186 1.7E-111 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 SUPERFAMILY SSF54534 60 191 4.91E-27 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 94 184 1.7E-19 T 16-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 246 332 9.7E-19 T 16-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 SUPERFAMILY SSF54534 223 332 5.11E-29 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 Gene3D G3DSA:3.10.50.40 63 197 2.3E-26 T 16-09-2016 Spa2297_RS06350 a3d372e2a3cb06646215633c00d8487c 335 Gene3D G3DSA:3.10.50.40 226 332 5.6E-27 T 16-09-2016 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 Gene3D G3DSA:1.10.10.10 125 217 8.6E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 PANTHER PTHR26402:SF553 1 217 1.9E-111 T 16-09-2016 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 SMART SM00448 1 112 2.6E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 PANTHER PTHR26402 1 217 1.9E-111 T 16-09-2016 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 Pfam PF00072 Response regulator receiver domain 3 113 1.7E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 Gene3D G3DSA:3.40.50.2300 2 119 2.6E-32 T 16-09-2016 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 8.1E-23 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 SUPERFAMILY SSF52172 2 172 3.08E-34 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24830 b23089e7363653c8c85d89ba78994be9 217 SMART SM00862 145 217 2.1E-22 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 411 5.9E-113 T 16-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 SUPERFAMILY SSF69055 316 410 5.62E-24 T 16-09-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 SUPERFAMILY SSF55347 152 288 2.81E-53 T 16-09-2016 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 SUPERFAMILY SSF51735 23 174 1.42E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 170 253 2.5E-36 T 16-09-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 26 409 44.572 T 16-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 PANTHER PTHR30525 3 418 4.3E-211 T 16-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Pfam PF13288 DXP reductoisomerase C-terminal domain 287 404 3.1E-30 T 16-09-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 26 158 1.8E-40 T 16-09-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 PANTHER PTHR30525:SF0 3 418 4.3E-211 T 16-09-2016 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Gene3D G3DSA:1.10.1740.10 327 410 9.5E-28 T 16-09-2016 Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 Gene3D G3DSA:3.40.50.720 22 174 5.9E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24105 073f59ecb7aca05f64431c4d3b3481c5 418 PIRSF PIRSF006205 23 416 5.2E-143 T 16-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 PANTHER PTHR10242:SF3 262 489 3.0E-113 T 16-09-2016 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Pfam PF12833 Helix-turn-helix domain 106 185 6.3E-17 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 PANTHER PTHR10242 197 243 3.0E-113 T 16-09-2016 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 PANTHER PTHR10242 262 489 3.0E-113 T 16-09-2016 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SUPERFAMILY SSF48150 304 480 1.08E-39 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Gene3D G3DSA:1.10.10.60 136 185 1.6E-9 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Pfam PF02805 Metal binding domain of Ada 8 71 2.1E-26 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SMART SM00342 100 183 3.6E-18 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Pfam PF06029 AlkA N-terminal domain 201 315 1.2E-30 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Gene3D G3DSA:1.10.340.30 318 432 2.3E-33 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 PANTHER PTHR10242:SF3 197 243 3.0E-113 T 16-09-2016 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SMART SM01009 200 315 2.6E-48 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Gene3D G3DSA:3.40.10.10 2 82 2.2E-32 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 321 470 2.8E-5 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SUPERFAMILY SSF46689 137 186 1.57E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Gene3D G3DSA:1.10.1670.10 433 483 1.9E-17 T 16-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SUPERFAMILY SSF57884 2 81 8.5E-30 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SMART SM00478 325 482 1.1E-30 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 Gene3D G3DSA:3.30.310.20 200 315 1.3E-34 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS26880 f93724204e808abf3e8f7316618cae2c 490 SUPERFAMILY SSF55945 201 296 8.0E-27 T 16-09-2016 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 Pfam PF00892 EamA-like transporter family 172 305 1.2E-21 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 Pfam PF00892 EamA-like transporter family 31 163 3.0E-18 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 SUPERFAMILY SSF103481 64 166 1.31E-5 T 16-09-2016 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 SUPERFAMILY SSF103481 207 306 1.03E-13 T 16-09-2016 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 PANTHER PTHR12715:SF12 4 311 5.9E-95 T 16-09-2016 Spa2297_RS11205 6ff54b2e819179d5390f92eaed9e1b72 311 PANTHER PTHR12715 4 311 5.9E-95 T 16-09-2016 Spa2297_RS01240 003a5809ae80df2c7b435f901e1f84f6 493 Gene3D G3DSA:2.115.10.20 49 353 1.9E-76 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS01240 003a5809ae80df2c7b435f901e1f84f6 493 Pfam PF04616 Glycosyl hydrolases family 43 54 337 1.2E-65 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS01240 003a5809ae80df2c7b435f901e1f84f6 493 PANTHER PTHR22925 3 361 7.0E-137 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS01240 003a5809ae80df2c7b435f901e1f84f6 493 PANTHER PTHR22925:SF12 3 361 7.0E-137 T 16-09-2016 Spa2297_RS01240 003a5809ae80df2c7b435f901e1f84f6 493 SUPERFAMILY SSF75005 47 338 9.95E-55 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 Pfam PF12680 SnoaL-like domain 187 282 7.4E-7 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 Gene3D G3DSA:1.10.10.10 118 171 2.4E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 PANTHER PTHR30173:SF11 4 296 1.4E-105 T 16-09-2016 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 SUPERFAMILY SSF88659 112 171 1.87E-7 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 PANTHER PTHR30173 4 296 1.4E-105 T 16-09-2016 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 Gene3D G3DSA:1.10.1740.10 8 79 4.4E-15 T 16-09-2016 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 Pfam PF04542 Sigma-70 region 2 14 77 6.1E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 SUPERFAMILY SSF88946 7 87 1.49E-16 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 171 7.2E-18 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 Gene3D G3DSA:3.10.450.50 182 295 2.7E-9 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS29695 b5b28f8625a243fcf30f7680e4004ada 303 SUPERFAMILY SSF54427 183 297 2.2E-14 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PANTHER PTHR24322 161 192 8.0E-50 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PANTHER PTHR24322 12 145 8.0E-50 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 SUPERFAMILY SSF51735 7 253 7.88E-76 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.7E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 Gene3D G3DSA:3.40.50.720 4 253 3.9E-80 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PANTHER PTHR24322:SF211 161 192 8.0E-50 T 16-09-2016 Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PANTHER PTHR24322:SF211 12 145 8.0E-50 T 16-09-2016 Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 4.3E-60 T 16-09-2016 Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 196 2.6E-4 T 16-09-2016 Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.2E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29285 160ce112512ffc06e11786d9f9594b34 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.2E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01425 2716db71449b733bed504a337f8459ab 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 177 281 5.6E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01425 2716db71449b733bed504a337f8459ab 390 SUPERFAMILY SSF55874 162 282 4.19E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01425 2716db71449b733bed504a337f8459ab 390 Gene3D G3DSA:3.30.565.10 177 284 1.1E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01425 2716db71449b733bed504a337f8459ab 390 PANTHER PTHR24423:SF508 28 355 1.9E-53 T 16-09-2016 Spa2297_RS01425 2716db71449b733bed504a337f8459ab 390 PANTHER PTHR24423 28 355 1.9E-53 T 16-09-2016 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 Pfam PF00072 Response regulator receiver domain 15 126 5.5E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 Gene3D G3DSA:1.10.10.10 163 219 5.9E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 SMART SM00421 160 217 2.0E-25 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 SMART SM00448 13 126 5.6E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 PANTHER PTHR26402:SF151 13 221 2.3E-71 T 16-09-2016 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 5.2E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 PANTHER PTHR26402 13 221 2.3E-71 T 16-09-2016 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 Gene3D G3DSA:3.40.50.2300 12 162 3.2E-36 T 16-09-2016 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 SUPERFAMILY SSF46894 155 219 1.77E-19 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS03970 93fad22d05c07b4803a986e124eaa5e1 231 SUPERFAMILY SSF52172 13 141 5.12E-30 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 PIRSF PIRSF000190 2 222 5.1E-86 T 16-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 181 222 5.4E-20 T 16-09-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 PANTHER PTHR10851 4 222 3.0E-110 T 16-09-2016 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 PANTHER PTHR10851:SF0 4 222 3.0E-110 T 16-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 SUPERFAMILY SSF50475 20 222 9.54E-65 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 51 125 4.9E-23 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 9 222 2.3E-83 T 16-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 17 222 39.967 T 16-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 191 204 - T 16-09-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14475 906d44867049ceb17f3b0563bd502e25 222 Gene3D G3DSA:2.30.110.10 23 222 2.8E-84 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS13820 c59cd373cdaef18fca38ed18c6ddf575 161 Gene3D G3DSA:3.40.630.30 9 158 1.5E-24 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13820 c59cd373cdaef18fca38ed18c6ddf575 161 SUPERFAMILY SSF55729 7 157 5.75E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13820 c59cd373cdaef18fca38ed18c6ddf575 161 PANTHER PTHR13947 33 161 2.3E-25 T 16-09-2016 Spa2297_RS13820 c59cd373cdaef18fca38ed18c6ddf575 161 Pfam PF00583 Acetyltransferase (GNAT) family 54 137 3.4E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 312 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 PANTHER PTHR23508 13 427 4.8E-221 T 16-09-2016 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 Pfam PF07690 Major Facilitator Superfamily 29 281 8.4E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 Gene3D G3DSA:1.20.1250.20 16 224 2.9E-26 T 16-09-2016 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 Gene3D G3DSA:1.20.1250.20 239 424 3.5E-26 T 16-09-2016 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 PANTHER PTHR23508:SF4 13 427 4.8E-221 T 16-09-2016 Spa2297_RS27825 0651c22da56133eaafef4a18e1ceba71 427 SUPERFAMILY SSF103473 13 421 1.96E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS29000 62f5a876d366f636d171c2904a333b73 270 PIRSF PIRSF017393 1 270 1.2E-95 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS29000 62f5a876d366f636d171c2904a333b73 270 SUPERFAMILY SSF53335 16 254 1.69E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29000 62f5a876d366f636d171c2904a333b73 270 Gene3D G3DSA:3.40.50.150 1 268 5.3E-107 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29000 62f5a876d366f636d171c2904a333b73 270 Pfam PF04672 S-adenosyl methyltransferase 5 269 2.3E-105 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 Pfam PF03422 Carbohydrate binding module (family 6) 338 465 3.4E-41 T 16-09-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 PANTHER PTHR10963 43 351 2.6E-154 T 16-09-2016 Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 SMART SM00606 330 466 9.3E-62 T 16-09-2016 IPR006584 Cellulose binding, type IV GO:0030246 Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 Gene3D G3DSA:2.60.120.260 331 465 7.2E-43 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 SUPERFAMILY SSF49785 329 465 2.38E-33 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 Gene3D G3DSA:2.60.120.200 39 317 6.6E-59 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 SUPERFAMILY SSF49899 45 315 1.46E-52 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 PANTHER PTHR10963:SF41 43 351 2.6E-154 T 16-09-2016 Spa2297_RS27720 c25c6434249845648a761c85a147681f 466 Pfam PF00722 Glycosyl hydrolases family 16 94 312 3.8E-15 T 16-09-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 16-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PANTHER PTHR12128:SF34 1 298 9.7E-110 T 16-09-2016 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 16-09-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 Gene3D G3DSA:3.20.20.70 4 298 1.6E-95 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PIRSF PIRSF001365 10 307 4.0E-80 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 291 7.7E-66 T 16-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 297 50.681 T 16-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 SUPERFAMILY SSF51569 10 298 3.45E-89 T 16-09-2016 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 Pfam PF00701 Dihydrodipicolinate synthetase family 12 289 1.7E-69 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 4.7E-27 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 4.7E-27 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 4.7E-27 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 4.7E-27 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 SMART SM01130 11 299 2.2E-102 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07635 cabd0da7aec43ee7dc164950c415b5cf 307 PANTHER PTHR12128 1 298 9.7E-110 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 SUPERFAMILY SSF48498 92 177 1.71E-9 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 SUPERFAMILY SSF46689 5 73 1.08E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.7E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 Gene3D G3DSA:1.10.357.10 8 177 2.7E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 PANTHER PTHR30328 1 177 1.0E-28 T 16-09-2016 Spa2297_RS07715 35dea46a8a352ef99c1df6d97ff70434 181 PANTHER PTHR30328:SF11 1 177 1.0E-28 T 16-09-2016 Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 PANTHER PTHR12001 32 357 5.4E-201 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 Pfam PF00348 Polyprenyl synthetase 65 290 9.0E-50 T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 SUPERFAMILY SSF48576 37 356 1.44E-72 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 Gene3D G3DSA:1.10.600.10 41 356 1.4E-78 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 104 118 - T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS28170 3c73e0ceb98911208edb3831a627012d 357 PANTHER PTHR12001:SF51 32 357 5.4E-201 T 16-09-2016 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 2.4E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 SMART SM00421 160 217 8.2E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 Pfam PF00072 Response regulator receiver domain 12 124 7.9E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 Gene3D G3DSA:3.40.50.2300 7 131 1.7E-39 T 16-09-2016 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 PANTHER PTHR26402 10 224 1.7E-103 T 16-09-2016 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 SUPERFAMILY SSF52172 10 139 3.27E-33 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 SMART SM00448 10 123 2.1E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 Gene3D G3DSA:1.10.10.10 132 224 2.6E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 PANTHER PTHR26402:SF564 10 224 1.7E-103 T 16-09-2016 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.3E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.3E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.3E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17630 aac3e2fe01c4bfc47b79f567984f6fe6 228 SUPERFAMILY SSF46894 149 223 6.12E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS25320 609664a3dc3dd3a61165fa8f5c0ff1e2 586 Pfam PF17102 Stealth protein CR3, conserved region 3 460 507 3.7E-17 T 16-09-2016 IPR031357 Stealth protein CR3, conserved region 3 Spa2297_RS25320 609664a3dc3dd3a61165fa8f5c0ff1e2 586 PANTHER PTHR24045 27 580 1.8E-96 T 16-09-2016 Spa2297_RS25320 609664a3dc3dd3a61165fa8f5c0ff1e2 586 Pfam PF11380 Stealth protein CR2, conserved region 2 309 414 8.8E-46 T 16-09-2016 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 KEGG: 00563+2.7.-.- Spa2297_RS25320 609664a3dc3dd3a61165fa8f5c0ff1e2 586 Pfam PF17101 Stealth protein CR1, conserved region 1 273 300 1.2E-13 T 16-09-2016 IPR031358 Stealth protein CR1, conserved region 1 KEGG: 00563+2.7.-.- Spa2297_RS25320 609664a3dc3dd3a61165fa8f5c0ff1e2 586 Pfam PF17103 Stealth protein CR4, conserved region 4 536 583 2.5E-13 T 16-09-2016 IPR031356 Stealth protein CR4, conserved region 4 Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 4.1E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 PANTHER PTHR30328:SF7 1 171 7.8E-47 T 16-09-2016 Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 SUPERFAMILY SSF48498 105 175 7.87E-6 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 Gene3D G3DSA:1.10.357.10 9 196 1.4E-24 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 SUPERFAMILY SSF46689 11 80 3.89E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25020 a6f3eefec7bc2092c8d289c5268768a9 219 PANTHER PTHR30328 1 171 7.8E-47 T 16-09-2016 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 211 368 2.2E-49 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 371 546 1.0E-54 T 16-09-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 67 108 7.4E-14 T 16-09-2016 IPR011096 FTP domain Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 SUPERFAMILY SSF55486 208 547 5.86E-83 T 16-09-2016 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 359 375 5.3E-20 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 322 342 5.3E-20 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 448 464 5.3E-20 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 380 391 5.3E-20 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PANTHER PTHR33794:SF2 53 547 2.3E-201 T 16-09-2016 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 PANTHER PTHR33794 53 547 2.3E-201 T 16-09-2016 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 Gene3D G3DSA:1.10.390.10 373 546 8.8E-55 T 16-09-2016 Spa2297_RS10450 256e7632874b55e32c375772b8c35cb7 547 Gene3D G3DSA:3.10.170.10 210 371 1.2E-46 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 PANTHER PTHR32507:SF7 1 502 3.6E-220 T 16-09-2016 IPR030151 K(+)/H(+) antiporter NhaP GO:0005451|GO:0006813|GO:0016021 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 Pfam PF00999 Sodium/hydrogen exchanger family 23 393 4.5E-48 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 Pfam PF02080 TrkA-C domain 422 477 1.7E-10 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 SUPERFAMILY SSF116726 417 483 1.83E-10 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 Gene3D G3DSA:3.30.70.1450 419 477 6.3E-7 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS13870 1933a7d4ec7f22a7dcad0854c3bda23c 510 PANTHER PTHR32507 1 502 3.6E-220 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 PANTHER PTHR30061 13 449 3.1E-72 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 Pfam PF01547 Bacterial extracellular solute-binding protein 96 323 3.6E-17 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 PANTHER PTHR30061:SF1 13 449 3.1E-72 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 Gene3D G3DSA:3.40.190.10 57 172 3.7E-20 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 Gene3D G3DSA:3.40.190.10 343 401 3.7E-20 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 Gene3D G3DSA:3.40.190.10 174 342 1.8E-22 T 16-09-2016 Spa2297_RS01230 59998a9dc579f2b3fc11774930b7b453 454 SUPERFAMILY SSF53850 57 444 1.28E-51 T 16-09-2016 Spa2297_RS14160 b3df060af1f26421a4e676f8ca11a7c7 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 9.2E-225 T 16-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Spa2297_RS14160 b3df060af1f26421a4e676f8ca11a7c7 554 PANTHER PTHR30607 4 554 4.5E-300 T 16-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Spa2297_RS14160 b3df060af1f26421a4e676f8ca11a7c7 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 553 1.4E-202 T 16-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Spa2297_RS14160 b3df060af1f26421a4e676f8ca11a7c7 554 PIRSF PIRSF001294 4 554 2.0E-215 T 16-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Spa2297_RS14160 b3df060af1f26421a4e676f8ca11a7c7 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.789 T 16-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Spa2297_RS13295 af8782907cbaf42664b15dd30dd7f658 501 PIRSF PIRSF006060 2 489 1.7E-61 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS13295 af8782907cbaf42664b15dd30dd7f658 501 PANTHER PTHR11785 20 469 1.1E-60 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS13295 af8782907cbaf42664b15dd30dd7f658 501 Pfam PF13520 Amino acid permease 28 459 3.3E-45 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS00430 4e4b75a2d7a3f9bf0adbf6a11eef61ab 259 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 44 71 - T 16-09-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Spa2297_RS00430 4e4b75a2d7a3f9bf0adbf6a11eef61ab 259 PANTHER PTHR10108 13 134 7.1E-25 T 16-09-2016 Spa2297_RS00430 4e4b75a2d7a3f9bf0adbf6a11eef61ab 259 Gene3D G3DSA:3.40.50.150 9 140 8.9E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00430 4e4b75a2d7a3f9bf0adbf6a11eef61ab 259 SUPERFAMILY SSF53335 6 153 1.04E-31 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00430 4e4b75a2d7a3f9bf0adbf6a11eef61ab 259 Pfam PF08241 Methyltransferase domain 45 134 6.0E-18 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS22770 74ead8c1d8d986e93367e8503c6ee620 223 PANTHER PTHR38814 1 223 3.3E-180 T 16-09-2016 Spa2297_RS22770 74ead8c1d8d986e93367e8503c6ee620 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.528 T 16-09-2016 IPR002793 Endonuclease NucS Spa2297_RS22770 74ead8c1d8d986e93367e8503c6ee620 223 Pfam PF01939 Protein of unknown function DUF91 2 223 1.4E-85 T 16-09-2016 IPR002793 Endonuclease NucS Spa2297_RS22770 74ead8c1d8d986e93367e8503c6ee620 223 PANTHER PTHR38814:SF2 1 223 3.3E-180 T 16-09-2016 Spa2297_RS23660 4ded9576496f5be951f0cc9301b1c8c7 389 Gene3D G3DSA:3.40.33.10 265 385 5.5E-11 T 16-09-2016 IPR014044 CAP domain Spa2297_RS23660 4ded9576496f5be951f0cc9301b1c8c7 389 PANTHER PTHR31157 269 388 1.2E-46 T 16-09-2016 Spa2297_RS23660 4ded9576496f5be951f0cc9301b1c8c7 389 SUPERFAMILY SSF55797 268 388 2.59E-24 T 16-09-2016 IPR014044 CAP domain Spa2297_RS23660 4ded9576496f5be951f0cc9301b1c8c7 389 Pfam PF00188 Cysteine-rich secretory protein family 273 387 7.8E-20 T 16-09-2016 IPR014044 CAP domain Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 SUPERFAMILY SSF47807 182 293 1.32E-19 T 16-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 SUPERFAMILY SSF88723 1 160 5.1E-39 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 SMART SM00279 180 215 7.9E-12 T 16-09-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 SMART SM00475 1 270 1.6E-82 T 16-09-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 181 263 2.7E-18 T 16-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 PANTHER PTHR10133 1 288 8.1E-101 T 16-09-2016 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 PANTHER PTHR10133:SF27 1 288 8.1E-101 T 16-09-2016 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 Gene3D G3DSA:3.40.50.1010 1 175 4.7E-49 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 177 6.7E-48 T 16-09-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Spa2297_RS06265 1fca37f8744b179a43ecab757b2c6192 301 Gene3D G3DSA:1.10.150.20 176 233 7.6E-20 T 16-09-2016 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 Gene3D G3DSA:1.10.10.10 148 243 1.1E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 SUPERFAMILY SSF52172 16 139 1.18E-40 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 PANTHER PTHR26402:SF292 20 243 1.8E-95 T 16-09-2016 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 SMART SM00862 170 241 3.0E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 Pfam PF00072 Response regulator receiver domain 22 130 7.7E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 Gene3D G3DSA:3.40.50.2300 16 138 1.8E-38 T 16-09-2016 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 SMART SM00448 20 130 1.7E-40 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 PANTHER PTHR26402 20 243 1.8E-95 T 16-09-2016 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 171 241 1.1E-23 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS22320 5b1d5dbdc6e3296dbe034bddd44dda7b 246 SUPERFAMILY SSF46894 147 242 8.22E-27 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 226 314 4.0E-27 T 16-09-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 SUPERFAMILY SSF53901 5 315 1.6E-59 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 PANTHER PTHR18919 28 316 1.4E-111 T 16-09-2016 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 PANTHER PTHR18919:SF109 28 316 1.4E-111 T 16-09-2016 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 315 59.683 T 16-09-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 Gene3D G3DSA:3.40.47.10 161 315 2.2E-39 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 314 5.7E-92 T 16-09-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 Gene3D G3DSA:3.40.47.10 2 160 4.1E-59 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS27330 b0d5c3f7001610a093b5bd006c5e5661 316 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 182 1.2E-26 T 16-09-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS15915 574abbd8c7640a1c86f7e48f4ee430a0 196 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 190 1.5E-13 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS15915 574abbd8c7640a1c86f7e48f4ee430a0 196 Gene3D G3DSA:1.10.340.30 16 137 3.4E-9 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS15915 574abbd8c7640a1c86f7e48f4ee430a0 196 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 192 8.9E-100 T 16-09-2016 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD Spa2297_RS15915 574abbd8c7640a1c86f7e48f4ee430a0 196 SUPERFAMILY SSF48150 8 142 1.27E-12 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 PANTHER PTHR10366 2 327 3.6E-88 T 16-09-2016 Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 SUPERFAMILY SSF51735 2 307 1.14E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 Gene3D G3DSA:3.40.50.720 2 202 1.3E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 3.1E-40 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 PANTHER PTHR10366:SF12 2 327 3.6E-88 T 16-09-2016 Spa2297_RS31745 7c01321427d3932da77a9ea231dbd210 341 Gene3D G3DSA:3.90.25.10 203 308 1.4E-12 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 PANTHER PTHR30363 5 256 7.6E-90 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 Pfam PF00455 DeoR C terminal sensor domain 78 235 2.8E-45 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 Pfam PF08220 DeoR-like helix-turn-helix domain 9 61 5.5E-15 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 SMART SM01134 76 237 1.8E-58 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 SMART SM00420 9 61 2.3E-12 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 PANTHER PTHR30363:SF1 5 256 7.6E-90 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 1.0E-8 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 1.0E-8 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 Gene3D G3DSA:3.40.50.1360 81 216 5.0E-7 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 Gene3D G3DSA:1.10.10.10 8 60 1.2E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 SUPERFAMILY SSF100950 78 237 2.57E-24 T 16-09-2016 Spa2297_RS07570 57905e01cb619a749e834cfd9689b23c 256 SUPERFAMILY SSF46785 7 76 4.18E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21160 e76617bd1c4e39130024999e8a298b5e 235 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 9 220 1.3E-27 T 16-09-2016 IPR017592 Pilus assembly, Flp-type CpaB Spa2297_RS21160 e76617bd1c4e39130024999e8a298b5e 235 Pfam PF08666 SAF domain 48 102 1.1E-4 T 16-09-2016 IPR013974 SAF domain Spa2297_RS21160 e76617bd1c4e39130024999e8a298b5e 235 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 213 3.1E-19 T 16-09-2016 IPR031571 Flp pilus assembly protein RcpC/CpaB domain Spa2297_RS21160 e76617bd1c4e39130024999e8a298b5e 235 SMART SM00858 41 103 4.6E-4 T 16-09-2016 IPR013974 SAF domain Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 438 28.96 T 16-09-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 Gene3D G3DSA:3.65.10.10 30 250 7.4E-63 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 SUPERFAMILY SSF55205 15 434 9.81E-102 T 16-09-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 435 2.1E-112 T 16-09-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 Gene3D G3DSA:3.65.10.10 251 434 4.3E-54 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 PANTHER PTHR21090 19 438 3.0E-154 T 16-09-2016 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 430 1.5E-105 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 PANTHER PTHR21090:SF5 19 438 3.0E-154 T 16-09-2016 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 PIRSF PIRSF000505 8 438 1.0E-111 T 16-09-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 ProSitePatterns PS00104 EPSP synthase signature 1. 98 112 - T 16-09-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS22040 e9c7ca643a2346d8f94a35874a0d6dd4 438 ProSitePatterns PS00885 EPSP synthase signature 2. 351 369 - T 16-09-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 PANTHER PTHR23029:SF25 1 225 1.0E-142 T 16-09-2016 Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 SUPERFAMILY SSF53254 1 204 1.67E-44 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 203 3.6E-97 T 16-09-2016 IPR022492 Phosphomutase MSMEG4193, putative Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 1.3E-47 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 Gene3D G3DSA:3.40.50.1240 1 208 5.0E-46 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 SMART SM00855 3 162 3.6E-23 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS06480 ca1b70253cd123fbfb12205d8f2f57c7 228 PANTHER PTHR23029 1 225 1.0E-142 T 16-09-2016 Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 Gene3D G3DSA:3.40.710.10 244 541 1.2E-52 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 SUPERFAMILY SSF56601 239 540 7.86E-53 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 Pfam PF00905 Penicillin binding protein transpeptidase domain 264 539 9.2E-39 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 59 163 2.0E-8 T 16-09-2016 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 PANTHER PTHR30627:SF4 187 541 3.6E-155 T 16-09-2016 Spa2297_RS13725 867b1582877006d1826c0d7b0ee9aca3 543 PANTHER PTHR30627 187 541 3.6E-155 T 16-09-2016 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Gene3D G3DSA:1.20.140.10 244 394 2.3E-40 T 16-09-2016 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 390 9.9E-30 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 SUPERFAMILY SSF56645 10 242 3.66E-72 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Gene3D G3DSA:1.10.540.10 10 137 8.3E-35 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 PANTHER PTHR10909:SF152 8 397 1.4E-221 T 16-09-2016 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 231 7.4E-24 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 135 4.1E-27 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 SUPERFAMILY SSF47203 244 393 3.7E-40 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 Gene3D G3DSA:2.40.110.10 139 241 6.3E-36 T 16-09-2016 Spa2297_RS06885 b05fa795ec2cd9935912c15e91780e7b 397 PANTHER PTHR10909 8 397 1.4E-221 T 16-09-2016 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 414 515 1.5E-15 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Gene3D G3DSA:2.60.120.260 351 522 1.9E-22 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS11530 14113475781872253b728205f1d9417c 883 SUPERFAMILY SSF52540 571 804 2.4E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 199 1.4E-16 T 16-09-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 SUPERFAMILY SSF53474 39 321 1.3E-49 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11530 14113475781872253b728205f1d9417c 883 ProSitePatterns PS00211 ABC transporters family signature. 713 727 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Gene3D G3DSA:3.40.50.1820 39 318 5.6E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Gene3D G3DSA:3.40.50.300 580 801 3.5E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11530 14113475781872253b728205f1d9417c 883 Pfam PF00005 ABC transporter 601 741 1.6E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 SMART SM00382 609 789 7.9E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11530 14113475781872253b728205f1d9417c 883 SMART SM00939 310 533 3.0E-22 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 SUPERFAMILY SSF49785 351 530 1.64E-27 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS11530 14113475781872253b728205f1d9417c 883 PANTHER PTHR24220 583 802 5.7E-96 T 16-09-2016 Spa2297_RS11530 14113475781872253b728205f1d9417c 883 PANTHER PTHR24220:SF427 583 802 5.7E-96 T 16-09-2016 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 SUPERFAMILY SSF69065 26 183 1.92E-49 T 16-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 SUPERFAMILY SSF54768 135 246 3.3E-26 T 16-09-2016 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 Pfam PF00035 Double-stranded RNA binding motif 181 244 3.4E-17 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 Pfam PF14622 Ribonuclease-III-like 40 165 1.9E-38 T 16-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 Gene3D G3DSA:1.10.1520.10 30 171 6.6E-47 T 16-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 33 245 4.9E-73 T 16-09-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 SMART SM00358 181 247 3.1E-24 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 SMART SM00535 41 174 6.7E-62 T 16-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 PANTHER PTHR11207 6 249 1.0E-90 T 16-09-2016 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 Gene3D G3DSA:3.30.160.20 179 246 6.8E-26 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 ProSitePatterns PS00517 Ribonuclease III family signature. 63 71 - T 16-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 Spa2297_RS23645 dc19cd2fc5e25ddc9e2332abb8fac172 273 Hamap MF_00104 Ribonuclease 3 [rnc]. 30 243 30.691 T 16-09-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 SUPERFAMILY SSF53850 32 525 1.57E-99 T 16-09-2016 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 PANTHER PTHR30290 1 530 5.9E-201 T 16-09-2016 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 PANTHER PTHR30290:SF7 1 530 5.9E-201 T 16-09-2016 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 PIRSF PIRSF002741 2 528 1.1E-65 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 449 2.1E-72 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 Gene3D G3DSA:3.10.105.10 301 500 3.5E-43 T 16-09-2016 Spa2297_RS06425 a031ea29194c580bca8d2f7ada794b13 534 Gene3D G3DSA:3.40.190.10 145 300 7.8E-31 T 16-09-2016 Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 180 1.2E-47 T 16-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 SUPERFAMILY SSF52016 4 187 8.44E-47 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 Gene3D G3DSA:3.20.19.10 6 186 1.3E-35 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 34.09 T 16-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 PANTHER PTHR11670:SF27 2 192 5.0E-70 T 16-09-2016 Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 PANTHER PTHR11670 2 192 5.0E-70 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02890 1cedbbe15861670b073d4808f8a0e046 206 Pfam PF00694 Aconitase C-terminal domain 7 117 6.9E-20 T 16-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 Gene3D G3DSA:3.10.20.30 2 77 9.5E-27 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 SUPERFAMILY SSF54292 2 79 1.01E-20 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 PANTHER PTHR11908 123 188 8.0E-31 T 16-09-2016 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 PANTHER PTHR11908 1 78 8.0E-31 T 16-09-2016 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 53 4.8E-7 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 Pfam PF01799 [2Fe-2S] binding domain 121 187 1.5E-28 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 Gene3D G3DSA:1.10.150.120 120 195 2.2E-33 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS26170 e6cb7f664798b5fe96ba1c0688b17885 198 SUPERFAMILY SSF47741 121 193 1.7E-30 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 2 176 33.154 T 16-09-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 Gene3D G3DSA:3.40.50.300 3 177 5.7E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 169 2.6E-56 T 16-09-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 PANTHER PTHR11055 4 177 6.6E-105 T 16-09-2016 Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 SUPERFAMILY SSF52540 3 175 8.55E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 PANTHER PTHR11055:SF15 4 177 6.6E-105 T 16-09-2016 Spa2297_RS25770 c003f27f8acdde0af23b5c2632725055 178 Pfam PF01583 Adenylylsulphate kinase 4 160 1.2E-57 T 16-09-2016 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795 159 341 4.3E-56 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 Gene3D G3DSA:3.40.50.200 158 518 1.2E-77 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 182 201 2.5E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 243 2.5E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PRINTS PR00723 Subtilisin serine protease family (S8) signature 439 455 2.5E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 234 244 - T 16-09-2016 IPR022398 Peptidase S8, subtilisin, His-active site Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795 365 518 4.3E-56 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795:SF419 159 341 4.3E-56 T 16-09-2016 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795 39 71 4.3E-56 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 440 450 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 187 198 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795:SF419 39 71 4.3E-56 T 16-09-2016 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 PANTHER PTHR10795:SF419 365 518 4.3E-56 T 16-09-2016 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 SUPERFAMILY SSF52743 369 517 3.93E-72 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 SUPERFAMILY SSF52743 163 342 3.93E-72 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07270 90e47302b3cfd1bb9e157b2f835a4f41 518 Pfam PF00082 Subtilase family 184 476 3.6E-45 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS21970 5c97b0521f6efe648585540cdddb28bc 152 Gene3D G3DSA:3.90.1170.40 16 150 1.1E-47 T 16-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS21970 5c97b0521f6efe648585540cdddb28bc 152 Pfam PF02391 MoaE protein 22 132 3.1E-36 T 16-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS21970 5c97b0521f6efe648585540cdddb28bc 152 PANTHER PTHR23404:SF2 19 149 7.0E-37 T 16-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS21970 5c97b0521f6efe648585540cdddb28bc 152 PANTHER PTHR23404 19 149 7.0E-37 T 16-09-2016 Spa2297_RS21970 5c97b0521f6efe648585540cdddb28bc 152 SUPERFAMILY SSF54690 18 150 5.89E-42 T 16-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 PANTHER PTHR23501 7 488 4.8E-268 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 PANTHER PTHR23501:SF15 7 488 4.8E-268 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 PANTHER PTHR23501:SF15 510 528 4.8E-268 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 Pfam PF07690 Major Facilitator Superfamily 21 414 3.0E-39 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 SUPERFAMILY SSF103473 251 467 2.79E-57 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 SUPERFAMILY SSF103473 15 205 2.79E-57 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 PANTHER PTHR23501 510 528 4.8E-268 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 Gene3D G3DSA:1.20.1250.20 22 194 1.2E-25 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 Gene3D G3DSA:1.20.1250.20 266 469 1.9E-23 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 Pfam PF13620 Carboxypeptidase regulatory-like domain 501 575 1.1E-11 T 16-09-2016 Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 SUPERFAMILY SSF49464 501 579 2.35E-10 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS09660 ebc25b727688495771da44bc4c4cf227 585 Gene3D G3DSA:2.60.40.1120 501 578 9.5E-9 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS21735 f0032708a79118c4e561bdcb8674986f 199 Pfam PF06210 Protein of unknown function (DUF1003) 58 159 5.2E-41 T 16-09-2016 IPR010406 Protein of unknown function DUF1003 Spa2297_RS21735 f0032708a79118c4e561bdcb8674986f 199 PANTHER PTHR41386 1 199 1.4E-70 T 16-09-2016 Spa2297_RS21735 f0032708a79118c4e561bdcb8674986f 199 PANTHER PTHR41386:SF1 1 199 1.4E-70 T 16-09-2016 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 PRINTS PR00502 NUDIX hydrolase family signature 32 46 3.5E-9 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 PRINTS PR00502 NUDIX hydrolase family signature 46 61 3.5E-9 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 PANTHER PTHR22769 1 128 2.3E-26 T 16-09-2016 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 Pfam PF00293 NUDIX domain 4 118 9.1E-19 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 SUPERFAMILY SSF55811 4 130 5.55E-29 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 Gene3D G3DSA:3.90.79.10 2 130 4.0E-30 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS21510 2e2492d03de6a6a9efc73a8b97e6d7f8 140 PANTHER PTHR22769:SF35 1 128 2.3E-26 T 16-09-2016 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 401 427 4.0E-29 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 349 368 4.0E-29 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 4.0E-29 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 261 285 4.0E-29 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 186 210 4.0E-29 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 Pfam PF00361 Proton-conducting membrane transporter 139 443 3.8E-67 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PANTHER PTHR22773:SF40 1 513 1.5E-183 T 16-09-2016 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 PANTHER PTHR22773 1 513 1.5E-183 T 16-09-2016 Spa2297_RS19255 62301d353cc0464c75280445ac6a0df0 523 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 509 4.8E-180 T 16-09-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 5.5E-31 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Gene3D G3DSA:1.20.140.10 224 389 4.8E-69 T 16-09-2016 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 PANTHER PTHR10909:SF10 13 389 3.1E-174 T 16-09-2016 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 7.6E-28 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 348 367 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 PANTHER PTHR10909 13 389 3.1E-174 T 16-09-2016 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Gene3D G3DSA:2.40.110.10 128 223 2.4E-41 T 16-09-2016 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 SUPERFAMILY SSF56645 12 247 2.09E-80 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 389 4.2E-50 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 SUPERFAMILY SSF47203 233 389 3.14E-58 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS13220 ec3966ccca2bbe0eefdc6d7768cc8665 390 Gene3D G3DSA:1.10.540.10 13 124 1.2E-34 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 Pfam PF01472 PUA domain 275 349 3.9E-19 T 16-09-2016 IPR002478 PUA domain GO:0003723 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 SUPERFAMILY SSF53633 5 254 1.83E-61 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 256 35.197 T 16-09-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PIRSF PIRSF000729 1 367 3.1E-119 T 16-09-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 SMART SM00359 275 354 6.5E-18 T 16-09-2016 IPR002478 PUA domain GO:0003723 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PANTHER PTHR11063 3 368 7.6E-107 T 16-09-2016 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 Gene3D G3DSA:3.40.1160.10 5 254 2.4E-54 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PANTHER PTHR11063:SF6 3 368 7.6E-107 T 16-09-2016 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PRINTS PR00474 Glutamate 5-kinase family signature 117 138 7.0E-53 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PRINTS PR00474 Glutamate 5-kinase family signature 43 57 7.0E-53 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PRINTS PR00474 Glutamate 5-kinase family signature 210 230 7.0E-53 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PRINTS PR00474 Glutamate 5-kinase family signature 77 105 7.0E-53 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 PRINTS PR00474 Glutamate 5-kinase family signature 149 176 7.0E-53 T 16-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 6.7E-123 T 16-09-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 Gene3D G3DSA:2.30.130.10 272 364 1.3E-24 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 ProSitePatterns PS00902 Glutamate 5-kinase signature. 208 225 - T 16-09-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 SUPERFAMILY SSF88697 275 365 1.82E-21 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS10925 75531296e39cab793e3ce3357305987f 368 Pfam PF00696 Amino acid kinase family 6 236 1.1E-41 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624:SF67 83 300 0.0 T 16-09-2016 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 Gene3D G3DSA:3.40.50.970 66 478 2.1E-135 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624 565 793 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 899 0.0 T 16-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624:SF67 565 793 0.0 T 16-09-2016 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 300 3.0E-9 T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PIRSF PIRSF000156 5 900 0.0 T 16-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624 484 547 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 Gene3D G3DSA:3.40.50.920 726 900 1.2E-65 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 SUPERFAMILY SSF52518 66 477 1.08E-113 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 SUPERFAMILY SSF52922 724 900 3.34E-48 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624 809 892 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624 83 300 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 Gene3D G3DSA:3.40.50.970 484 720 2.8E-109 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624 372 461 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624:SF67 372 461 0.0 T 16-09-2016 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624:SF67 484 547 0.0 T 16-09-2016 Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 SUPERFAMILY SSF52518 485 717 1.28E-87 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09025 adde46cea18db71613ac232e697bd603 900 PANTHER PTHR11624:SF67 809 892 0.0 T 16-09-2016 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 PANTHER PTHR32243 190 327 1.4E-98 T 16-09-2016 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 Gene3D G3DSA:1.10.3720.10 36 315 1.3E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 PANTHER PTHR32243:SF40 30 171 1.4E-98 T 16-09-2016 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 SUPERFAMILY SSF161098 85 313 4.32E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 PANTHER PTHR32243 30 171 1.4E-98 T 16-09-2016 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 313 2.6E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22145 8870775d7cae9bd8efb7305b55df7402 328 PANTHER PTHR32243:SF40 190 327 1.4E-98 T 16-09-2016 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 2.3E-18 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 Gene3D G3DSA:1.10.357.10 67 206 8.0E-33 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.4E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.4E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 SUPERFAMILY SSF48498 95 205 4.75E-18 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 SUPERFAMILY SSF46689 18 98 5.13E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 PANTHER PTHR30055 13 208 8.5E-56 T 16-09-2016 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 PANTHER PTHR30055:SF75 13 208 8.5E-56 T 16-09-2016 Spa2297_RS06655 6d8135b754787ab73e28c963c646ef63 214 Gene3D G3DSA:1.10.10.60 20 66 3.3E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23725 500c5550db632819e752072424112c91 516 PANTHER PTHR11564:SF7 1 439 5.4E-244 T 16-09-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 Gene3D G3DSA:1.10.260.30 333 434 7.3E-37 T 16-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23725 500c5550db632819e752072424112c91 516 Pfam PF02978 Signal peptide binding domain 333 430 2.8E-30 T 16-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 1.4E-172 T 16-09-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 SMART SM00962 100 298 4.7E-109 T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23725 500c5550db632819e752072424112c91 516 SUPERFAMILY SSF47446 300 433 6.54E-42 T 16-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 Gene3D G3DSA:1.20.120.140 2 89 2.2E-34 T 16-09-2016 Spa2297_RS23725 500c5550db632819e752072424112c91 516 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.1E-20 T 16-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23725 500c5550db632819e752072424112c91 516 PANTHER PTHR11564 1 439 5.4E-244 T 16-09-2016 Spa2297_RS23725 500c5550db632819e752072424112c91 516 SMART SM00963 1 86 1.5E-33 T 16-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23725 500c5550db632819e752072424112c91 516 Pfam PF00448 SRP54-type protein, GTPase domain 100 297 1.9E-70 T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23725 500c5550db632819e752072424112c91 516 SMART SM00382 99 303 6.3E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23725 500c5550db632819e752072424112c91 516 Gene3D G3DSA:3.40.50.300 94 299 6.3E-74 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23725 500c5550db632819e752072424112c91 516 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 449 33.057 T 16-09-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Spa2297_RS23725 500c5550db632819e752072424112c91 516 SUPERFAMILY SSF52540 42 359 6.13E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 Gene3D G3DSA:3.40.50.880 56 275 2.2E-36 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 Pfam PF00652 Ricin-type beta-trefoil lectin domain 469 590 9.4E-29 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 Pfam PF06439 Domain of Unknown Function (DUF1080) 281 458 4.7E-42 T 16-09-2016 IPR010496 Domain of unknown function DUF1080 Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 Gene3D G3DSA:2.80.10.50 467 591 4.9E-41 T 16-09-2016 Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 PANTHER PTHR40469 30 353 9.7E-53 T 16-09-2016 Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 SUPERFAMILY SSF50370 474 592 7.83E-41 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 PANTHER PTHR40469:SF1 30 353 9.7E-53 T 16-09-2016 Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 SMART SM00458 469 593 2.3E-31 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 SUPERFAMILY SSF52317 56 279 1.74E-47 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS10360 f8940ce449ec615181abb2852ebc6234 593 Pfam PF06283 Trehalose utilisation 57 268 4.3E-80 T 16-09-2016 IPR029010 ThuA-like domain Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 SUPERFAMILY SSF46785 24 86 9.39E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 PANTHER PTHR18964 75 394 4.1E-82 T 16-09-2016 Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 Pfam PF00480 ROK family 99 384 3.7E-49 T 16-09-2016 IPR000600 ROK family Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 Gene3D G3DSA:3.30.420.40 98 234 1.8E-32 T 16-09-2016 Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 SUPERFAMILY SSF53067 99 390 2.63E-44 T 16-09-2016 Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 PANTHER PTHR18964:SF109 75 394 4.1E-82 T 16-09-2016 Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 Gene3D G3DSA:1.10.10.10 24 91 1.2E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04215 a18de254d00012191935894e68fcf0b8 402 Gene3D G3DSA:3.30.420.40 235 367 2.5E-46 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Pfam PF00684 DnaJ central domain 143 207 5.4E-13 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Gene3D G3DSA:2.60.260.20 210 253 5.7E-21 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Gene3D G3DSA:2.60.260.20 99 136 5.7E-21 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PANTHER PTHR24078:SF190 3 357 8.7E-163 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Gene3D G3DSA:2.10.230.10 137 209 1.3E-19 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SUPERFAMILY SSF49493 213 256 1.7E-19 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SUPERFAMILY SSF49493 115 148 1.7E-19 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SUPERFAMILY SSF46565 3 99 1.7E-32 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Gene3D G3DSA:2.60.260.20 256 334 5.8E-21 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Pfam PF00226 DnaJ domain 4 65 5.2E-26 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Pfam PF01556 DnaJ C terminal domain 118 333 2.8E-39 T 16-09-2016 IPR002939 Chaperone DnaJ, C-terminal Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SMART SM00271 3 60 5.6E-31 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 349 1.6E-119 T 16-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SUPERFAMILY SSF57938 130 210 2.49E-18 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 374 37.93 T 16-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PRINTS PR00625 DnaJ domain signature 24 39 5.2E-24 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PRINTS PR00625 DnaJ domain signature 40 60 5.2E-24 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PRINTS PR00625 DnaJ domain signature 60 79 5.2E-24 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PRINTS PR00625 DnaJ domain signature 6 24 5.2E-24 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 SUPERFAMILY SSF49493 259 344 3.01E-21 T 16-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 PANTHER PTHR24078 3 357 8.7E-163 T 16-09-2016 Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 16-09-2016 IPR018253 DnaJ domain, conserved site Spa2297_RS10755 41f0adfb1afbf0bb03414e0a58588212 378 Gene3D G3DSA:1.10.287.110 3 98 4.0E-33 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS08790 8018499759ef9833f9e9c716df0ac892 346 Gene3D G3DSA:3.90.1720.10 227 334 1.5E-39 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS08790 8018499759ef9833f9e9c716df0ac892 346 PANTHER PTHR21666 226 337 2.5E-34 T 16-09-2016 Spa2297_RS08790 8018499759ef9833f9e9c716df0ac892 346 SUPERFAMILY SSF54001 227 334 1.67E-36 T 16-09-2016 Spa2297_RS08790 8018499759ef9833f9e9c716df0ac892 346 Pfam PF00877 NlpC/P60 family 244 334 4.8E-24 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 Pfam PF10503 Esterase PHB depolymerase 75 202 8.0E-10 T 16-09-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 PANTHER PTHR10655 53 226 9.4E-40 T 16-09-2016 Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 SUPERFAMILY SSF53474 64 257 9.34E-28 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 SUPERFAMILY SSF53474 284 323 9.34E-28 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 PANTHER PTHR10655:SF33 53 226 9.4E-40 T 16-09-2016 Spa2297_RS17085 a4f449d25b097344e46ab797d935ba59 329 Gene3D G3DSA:3.40.50.1820 19 324 3.4E-40 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 119 669 5.5E-92 T 16-09-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 PANTHER PTHR32438:SF5 154 697 6.4E-196 T 16-09-2016 Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 PANTHER PTHR32438 154 697 6.4E-196 T 16-09-2016 Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 SUPERFAMILY SSF51445 614 691 5.05E-139 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 SUPERFAMILY SSF51445 154 579 5.05E-139 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 Gene3D G3DSA:3.20.20.80 617 672 4.5E-163 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 Gene3D G3DSA:3.20.20.80 153 582 4.5E-163 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11225 d9d6076e3543dce19e58055e85d3f2c4 703 Pfam PF02446 4-alpha-glucanotransferase 160 667 1.4E-115 T 16-09-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 468 530 2.3E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SMART SM00065 209 352 1.0E-10 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SMART SM00065 39 188 9.3E-22 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SUPERFAMILY SSF55781 25 197 1.4E-37 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 PANTHER PTHR11347:SF114 430 437 3.4E-44 T 16-09-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 PANTHER PTHR11347:SF114 26 353 3.4E-44 T 16-09-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Pfam PF07730 Histidine kinase 360 423 7.4E-12 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SMART SM00387 463 560 1.3E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Gene3D G3DSA:3.30.450.40 28 185 1.3E-35 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Gene3D G3DSA:3.30.450.40 200 344 5.2E-23 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Gene3D G3DSA:3.30.565.10 457 518 9.2E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SUPERFAMILY SSF55874 468 559 5.11E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 PANTHER PTHR11347 430 437 3.4E-44 T 16-09-2016 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 PANTHER PTHR11347 26 353 3.4E-44 T 16-09-2016 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 SUPERFAMILY SSF55781 209 355 3.71E-21 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Pfam PF13185 GAF domain 209 342 6.3E-16 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16280 4e0424e9fe5d3feb9f5ddff8edb741db 560 Pfam PF13185 GAF domain 39 178 1.4E-21 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 PANTHER PTHR11699 93 529 2.7E-223 T 16-09-2016 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 Gene3D G3DSA:3.40.605.10 93 308 1.6E-25 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 7 563 1.4E-304 T 16-09-2016 IPR011975 Phenylacetic acid degradation protein PaaN2 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 Pfam PF00171 Aldehyde dehydrogenase family 93 476 8.7E-32 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 Gene3D G3DSA:3.40.309.10 317 524 2.6E-29 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 PANTHER PTHR11699:SF165 93 529 2.7E-223 T 16-09-2016 Spa2297_RS16790 9b167d379445c2ac46ca443fe44bc2f2 563 SUPERFAMILY SSF53720 79 539 5.24E-57 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 SMART SM01012 58 113 5.2E-8 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 SUPERFAMILY SSF55785 477 570 5.06E-9 T 16-09-2016 IPR000014 PAS domain Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 SUPERFAMILY SSF81606 633 822 8.63E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Gene3D G3DSA:3.30.450.40 169 285 9.0E-4 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Gene3D G3DSA:1.10.10.10 62 116 3.2E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 SMART SM00331 618 826 2.7E-30 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 SUPERFAMILY SSF55781 170 309 3.38E-5 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Pfam PF03861 ANTAR domain 61 113 9.9E-9 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Gene3D G3DSA:3.30.450.20 445 568 1.7E-12 T 16-09-2016 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 PANTHER PTHR21021 109 118 5.6E-38 T 16-09-2016 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 PANTHER PTHR21021 591 826 5.6E-38 T 16-09-2016 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Pfam PF08447 PAS fold 477 562 1.5E-7 T 16-09-2016 IPR013655 PAS fold-3 GO:0005515 Spa2297_RS02050 8f450a33f593bb41ba76f5e34ae73db2 827 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 645 826 4.6E-43 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 SMART SM00421 137 194 2.0E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.9E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.9E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.9E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 SMART SM00448 1 114 7.1E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 Pfam PF00072 Response regulator receiver domain 3 114 2.2E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 SUPERFAMILY SSF46894 124 200 2.52E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 4.5E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 PANTHER PTHR26402 1 200 1.2E-77 T 16-09-2016 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 PANTHER PTHR26402:SF137 1 200 1.2E-77 T 16-09-2016 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 Gene3D G3DSA:3.40.50.2300 2 119 3.0E-34 T 16-09-2016 Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 Gene3D G3DSA:1.10.10.10 120 200 7.5E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15835 38dcebee5547510814459ca5be6d1592 200 SUPERFAMILY SSF52172 2 128 4.84E-31 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 499 1.6E-59 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 15 193 1.3E-61 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 SUPERFAMILY SSF48179 195 301 7.31E-28 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 SUPERFAMILY SSF51735 12 195 2.12E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Gene3D G3DSA:1.10.1040.10 198 293 1.8E-28 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Gene3D G3DSA:1.10.1040.10 504 595 1.2E-30 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Gene3D G3DSA:3.40.50.720 315 503 6.8E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Gene3D G3DSA:3.40.50.720 12 197 4.0E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 SUPERFAMILY SSF51735 319 499 1.1E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 SUPERFAMILY SSF48179 502 595 6.72E-28 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 PANTHER PTHR23309 479 601 1.3E-277 T 16-09-2016 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 PANTHER PTHR23309:SF24 9 310 1.3E-277 T 16-09-2016 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 PANTHER PTHR23309 9 310 1.3E-277 T 16-09-2016 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 196 292 1.0E-28 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 502 596 4.2E-32 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS26945 b6e89a68c884d3e5ee8d067fcdebb45b 601 PANTHER PTHR23309:SF24 479 601 1.3E-277 T 16-09-2016 Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 PANTHER PTHR33693 1 232 1.3E-105 T 16-09-2016 Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 PANTHER PTHR33693:SF2 1 232 1.3E-105 T 16-09-2016 Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 SMART SM00986 48 225 3.0E-31 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 SUPERFAMILY SSF52141 16 229 4.91E-45 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 Gene3D G3DSA:3.40.470.10 9 233 2.3E-55 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 Pfam PF03167 Uracil DNA glycosylase superfamily 48 226 5.0E-29 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS08065 eb0da5666d923cbcbd1ae94908881364 237 SMART SM00987 48 225 3.0E-31 T 16-09-2016 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 8.4E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 8.4E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 73 4.8E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 PANTHER PTHR30055 8 105 1.2E-30 T 16-09-2016 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 SUPERFAMILY SSF48498 185 246 8.9E-11 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 Gene3D G3DSA:1.10.357.10 17 140 1.6E-60 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 Gene3D G3DSA:1.10.357.10 186 248 1.6E-60 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 SUPERFAMILY SSF46689 17 99 1.1E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15605 41f6bd91de902a0b95d95c15804feb64 249 PANTHER PTHR30055:SF43 8 105 1.2E-30 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 PIRSF PIRSF006444 19 448 8.9E-201 T 16-09-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 SUPERFAMILY SSF56801 20 442 9.03E-64 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 Pfam PF00501 AMP-binding enzyme 99 306 1.1E-14 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 PANTHER PTHR24095 76 446 1.0E-203 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 Gene3D G3DSA:3.40.50.980 107 262 4.2E-12 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 Pfam PF14535 AMP-binding enzyme C-terminal domain 353 446 1.4E-25 T 16-09-2016 IPR028154 AMP-dependent ligase, C-terminal Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 PANTHER PTHR24095:SF175 76 446 1.0E-203 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 Gene3D G3DSA:3.30.300.30 343 446 2.0E-35 T 16-09-2016 Spa2297_RS01390 0b6bd10b89ae14155ad807685e1ef502 448 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 28 446 5.4E-207 T 16-09-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 PANTHER PTHR11935:SF117 1 234 7.2E-95 T 16-09-2016 Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 PANTHER PTHR11935 1 234 7.2E-95 T 16-09-2016 Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 SMART SM00849 19 228 1.6E-28 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 Pfam PF00753 Metallo-beta-lactamase superfamily 19 228 6.3E-30 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 SUPERFAMILY SSF56281 4 239 4.32E-44 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS02175 c1f4719fcb1d02e343154d62146ddea0 248 Gene3D G3DSA:3.60.15.10 4 244 9.8E-44 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Gene3D G3DSA:2.30.30.30 3 64 1.6E-30 T 16-09-2016 IPR014722 Ribosomal protein L2 domain 2 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 50.734 T 16-09-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 SMART SM01185 68 122 2.8E-26 T 16-09-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 PIRSF PIRSF005901 1 187 3.7E-66 T 16-09-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 SUPERFAMILY SSF50249 130 186 2.74E-17 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 SMART SM00841 130 185 2.0E-30 T 16-09-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 16-09-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 SUPERFAMILY SSF50104 2 64 1.81E-18 T 16-09-2016 IPR008991 Translation protein SH3-like domain Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 SUPERFAMILY SSF50249 66 127 1.07E-18 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 9.3E-26 T 16-09-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 3.8E-74 T 16-09-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 5.3E-21 T 16-09-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Gene3D G3DSA:2.40.50.140 130 186 9.6E-27 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 PANTHER PTHR30053 3 187 1.4E-86 T 16-09-2016 Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Gene3D G3DSA:2.40.50.140 65 128 4.2E-25 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05625 f7e868e367cab47c4f92d1303a66636a 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 1.7E-24 T 16-09-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 Gene3D G3DSA:3.40.30.10 3 153 3.3E-38 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 PANTHER PTHR10681:SF72 1 152 1.1E-84 T 16-09-2016 Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 Pfam PF00578 AhpC/TSA family 7 129 1.9E-28 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 PANTHER PTHR10681 1 152 1.1E-84 T 16-09-2016 Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 SUPERFAMILY SSF52833 4 153 1.1E-41 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS01930 e93fd661a21b3a6d67cce5238037af30 155 PIRSF PIRSF000239 2 153 1.0E-16 T 16-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 PANTHER PTHR21000 5 579 0.0 T 16-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 PANTHER PTHR21000:SF2 5 579 0.0 T 16-09-2016 Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 129 139 - T 16-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 SUPERFAMILY SSF52016 382 567 4.39E-56 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 SUPERFAMILY SSF143975 11 381 7.06E-120 T 16-09-2016 Spa2297_RS07535 3718e70511f1e97e39ce9f695fd25b1f 579 Pfam PF00920 Dehydratase family 46 562 5.2E-173 T 16-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS14975 003828edc2d8bd9a5a9f9a9e2072d4e3 474 Pfam PF07538 Clostridial hydrophobic W 344 378 4.6E-7 T 16-09-2016 IPR006637 Clostridial hydrophobic repeat Spa2297_RS14975 003828edc2d8bd9a5a9f9a9e2072d4e3 474 SMART SM00728 343 392 2.7E-11 T 16-09-2016 IPR006637 Clostridial hydrophobic repeat Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 ProSitePatterns PS01176 Initiation factor 2 signature. 565 587 - T 16-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PANTHER PTHR23115:SF184 80 441 7.4E-189 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Pfam PF00009 Elongation factor Tu GTP binding domain 111 271 2.7E-33 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Pfam PF11987 Translation-initiation factor 2 402 503 4.0E-34 T 16-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PANTHER PTHR23115 80 441 7.4E-189 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 612 15.902 T 16-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 27 72 6.4E-8 T 16-09-2016 IPR006847 Translation initiation factor IF-2, N-terminal Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PANTHER PTHR23115:SF184 466 609 7.4E-189 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Gene3D G3DSA:3.40.50.10050 412 492 3.3E-23 T 16-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 SUPERFAMILY SSF50447 283 367 5.55E-25 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Gene3D G3DSA:2.40.30.10 515 612 6.2E-31 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PANTHER PTHR23115 466 609 7.4E-189 T 16-09-2016 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 SUPERFAMILY SSF52540 107 273 4.32E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 SUPERFAMILY SSF52156 391 520 2.22E-36 T 16-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PRINTS PR00315 GTP-binding elongation factor signature 110 123 1.8E-10 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PRINTS PR00315 GTP-binding elongation factor signature 214 223 1.8E-10 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PRINTS PR00315 GTP-binding elongation factor signature 162 172 1.8E-10 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 PRINTS PR00315 GTP-binding elongation factor signature 178 189 1.8E-10 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 109 268 1.9E-30 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 SUPERFAMILY SSF50447 514 612 9.62E-26 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 19 611 3.9E-231 T 16-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Gene3D G3DSA:3.40.50.300 102 270 2.8E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24160 33e4836f90463561def4a3ace7a65dc3 613 Gene3D G3DSA:2.40.30.10 282 376 8.9E-24 T 16-09-2016 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 ProSitePatterns PS00321 recA signature. 214 222 - T 16-09-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 SMART SM00382 58 229 1.6E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 Gene3D G3DSA:3.40.50.300 29 268 1.1E-88 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 5.9E-176 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 SUPERFAMILY SSF52540 5 268 4.13E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 Hamap MF_00268 Protein RecA [recA]. 6 330 52.969 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 Gene3D G3DSA:3.30.250.10 269 327 1.5E-29 T 16-09-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PANTHER PTHR22942:SF1 6 336 2.8E-204 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PANTHER PTHR22942 6 336 2.8E-204 T 16-09-2016 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 SUPERFAMILY SSF54752 269 327 2.09E-21 T 16-09-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal Spa2297_RS24405 6ffafeb06b5fc061206e9d1d2060b551 371 Pfam PF00154 recA bacterial DNA recombination protein 8 269 1.3E-143 T 16-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PIRSF PIRSF006431 1 320 6.4E-116 T 16-09-2016 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 Pfam PF00561 alpha/beta hydrolase fold 37 301 4.2E-22 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PANTHER PTHR10992 3 177 1.8E-79 T 16-09-2016 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PANTHER PTHR10992 212 319 1.8E-79 T 16-09-2016 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PANTHER PTHR10992:SF757 3 177 1.8E-79 T 16-09-2016 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PANTHER PTHR10992:SF757 212 319 1.8E-79 T 16-09-2016 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 1.0E-10 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 36 44 1.0E-10 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 110 124 1.0E-10 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 8 314 2.3E-88 T 16-09-2016 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 Gene3D G3DSA:3.40.50.1820 6 315 6.8E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08060 83f6e88d860e4543bea58189c9505f3c 321 SUPERFAMILY SSF53474 4 301 7.57E-49 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20285 5dc1289c118a08fc6f635e2dc333a023 375 Pfam PF05762 VWA domain containing CoxE-like protein 140 359 9.5E-60 T 16-09-2016 IPR008912 Uncharacterised protein family CoxE-like Spa2297_RS20285 5dc1289c118a08fc6f635e2dc333a023 375 PANTHER PTHR30634:SF8 1 369 3.9E-166 T 16-09-2016 Spa2297_RS20285 5dc1289c118a08fc6f635e2dc333a023 375 SUPERFAMILY SSF53300 201 364 5.65E-24 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS20285 5dc1289c118a08fc6f635e2dc333a023 375 PANTHER PTHR30634 1 369 3.9E-166 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 PANTHER PTHR22604 1 213 3.0E-125 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 Gene3D G3DSA:3.40.50.720 3 138 1.9E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 PANTHER PTHR22604 283 416 3.0E-125 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 SUPERFAMILY SSF55347 132 217 1.06E-25 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 SUPERFAMILY SSF55347 275 337 1.06E-25 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 PANTHER PTHR22604:SF106 283 416 3.0E-125 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 209 1.0E-8 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 Gene3D G3DSA:3.30.360.10 139 216 2.3E-31 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 Gene3D G3DSA:3.30.360.10 285 416 2.3E-31 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 SUPERFAMILY SSF51735 4 153 4.96E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 PANTHER PTHR22604:SF106 1 213 3.0E-125 T 16-09-2016 Spa2297_RS30895 2581c147f005afe4fb3ea9e3953ac2b7 417 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 2.1E-18 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 PANTHER PTHR35399 22 695 9.8E-294 T 16-09-2016 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 PANTHER PTHR35399:SF2 22 695 9.8E-294 T 16-09-2016 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 SUPERFAMILY SSF63829 552 635 4.45E-7 T 16-09-2016 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 SUPERFAMILY SSF63829 350 384 4.45E-7 T 16-09-2016 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 SUPERFAMILY SSF63829 417 515 4.45E-7 T 16-09-2016 Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 Gene3D G3DSA:2.120.10.30 551 636 1.6E-4 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 Gene3D G3DSA:2.120.10.30 388 514 1.6E-4 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS17005 f9f2b9bf4079d14d0f464fadc01568cd 695 Pfam PF05787 Bacterial protein of unknown function (DUF839) 109 656 1.4E-179 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 292 3.7E-126 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 Pfam PF02629 CoA binding domain 6 103 6.5E-25 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PIRSF PIRSF001553 1 294 2.0E-114 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 SUPERFAMILY SSF52210 129 289 2.22E-47 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 5.2E-34 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 5.2E-34 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 5.2E-34 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 5.2E-34 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 Gene3D G3DSA:3.40.50.720 3 125 1.3E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 SMART SM00881 4 104 5.4E-28 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 Pfam PF00549 CoA-ligase 158 275 1.5E-13 T 16-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 16-09-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 PANTHER PTHR11117 1 293 4.7E-147 T 16-09-2016 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 Gene3D G3DSA:3.40.50.261 126 291 1.5E-66 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20300 149db38b35f3f627ae602badf65737d1 294 SUPERFAMILY SSF51735 1 128 6.45E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03855 7b18b1e903edb66466f5e374191d846e 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 7.4E-19 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS03855 7b18b1e903edb66466f5e374191d846e 107 PANTHER PTHR33336:SF5 1 102 4.7E-23 T 16-09-2016 Spa2297_RS03855 7b18b1e903edb66466f5e374191d846e 107 PANTHER PTHR33336 1 102 4.7E-23 T 16-09-2016 Spa2297_RS03855 7b18b1e903edb66466f5e374191d846e 107 SUPERFAMILY SSF54909 1 93 6.9E-27 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS03855 7b18b1e903edb66466f5e374191d846e 107 Gene3D G3DSA:3.30.70.900 1 89 2.5E-24 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 Gene3D G3DSA:1.20.1090.10 159 347 5.1E-61 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 PANTHER PTHR11496 3 353 3.7E-197 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 Gene3D G3DSA:3.40.50.1970 8 157 3.1E-28 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 5.2E-54 T 16-09-2016 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00940 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 SUPERFAMILY SSF56796 9 347 3.4E-59 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 PANTHER PTHR11496:SF67 3 353 3.7E-197 T 16-09-2016 Spa2297_RS28130 b4a894cb51ba667f1f78798d5460f605 353 PIRSF PIRSF000112 2 353 1.1E-95 T 16-09-2016 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 SMART SM00331 150 339 2.3E-4 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 176 302 2.8E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 SUPERFAMILY SSF81606 152 338 4.05E-12 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 PANTHER PTHR35801 8 337 2.6E-45 T 16-09-2016 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 Pfam PF13581 Histidine kinase-like ATPase domain 16 135 6.8E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 PANTHER PTHR35801:SF1 8 337 2.6E-45 T 16-09-2016 Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 Gene3D G3DSA:3.30.565.10 25 138 1.4E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29215 328e4c974692fad91a503f12ef3935e8 343 SUPERFAMILY SSF55874 38 137 6.02E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 SUPERFAMILY SSF53756 4 368 2.41E-66 T 16-09-2016 Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 Gene3D G3DSA:3.40.50.2000 151 317 4.0E-24 T 16-09-2016 Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 Pfam PF13439 Glycosyltransferase Family 4 13 171 8.0E-27 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 Pfam PF00534 Glycosyl transferases group 1 182 332 2.5E-17 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 PANTHER PTHR12526 2 375 2.9E-111 T 16-09-2016 Spa2297_RS11470 eed59de4063dc88a596559480d72f504 386 PANTHER PTHR12526:SF400 2 375 2.9E-111 T 16-09-2016 Spa2297_RS11485 203fddcc1d444b3add6e6a5e996c47f3 407 Pfam PF02156 Glycosyl hydrolase family 26 194 280 4.1E-7 T 16-09-2016 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 Spa2297_RS11485 203fddcc1d444b3add6e6a5e996c47f3 407 Gene3D G3DSA:3.20.20.80 60 340 3.7E-45 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11485 203fddcc1d444b3add6e6a5e996c47f3 407 SUPERFAMILY SSF51445 71 325 1.03E-35 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Pfam PF00550 Phosphopantetheine attachment site 1 61 1.7E-8 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 SUPERFAMILY SSF51161 186 308 8.87E-11 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Gene3D G3DSA:2.160.10.10 497 543 1.2E-22 T 16-09-2016 Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Gene3D G3DSA:2.160.10.10 716 799 1.2E-22 T 16-09-2016 Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 95 796 1.4E-211 T 16-09-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 718 732 0.11 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 749 777 0.0028 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Gene3D G3DSA:1.10.1200.10 2 64 4.3E-11 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 Gene3D G3DSA:2.160.10.10 155 306 2.2E-14 T 16-09-2016 Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 SUPERFAMILY SSF47336 2 82 1.31E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00690 e672c7f73b9f0a1e0ab9d1532fb8d6bb 807 SUPERFAMILY SSF51161 696 800 1.39E-17 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS16470 369e297523e26057a0fb17b47f123737 225 PANTHER PTHR33169:SF11 4 196 1.2E-82 T 16-09-2016 Spa2297_RS16470 369e297523e26057a0fb17b47f123737 225 Gene3D G3DSA:1.10.10.10 4 97 2.7E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16470 369e297523e26057a0fb17b47f123737 225 PANTHER PTHR33169 4 196 1.2E-82 T 16-09-2016 Spa2297_RS16470 369e297523e26057a0fb17b47f123737 225 SUPERFAMILY SSF46785 8 182 5.04E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16470 369e297523e26057a0fb17b47f123737 225 Pfam PF03551 Transcriptional regulator PadR-like family 12 92 4.3E-15 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 Pfam PF13560 Helix-turn-helix domain 12 71 6.5E-16 T 16-09-2016 Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 SUPERFAMILY SSF47413 8 69 5.07E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 PANTHER PTHR10245 5 285 8.9E-119 T 16-09-2016 Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 PANTHER PTHR10245:SF7 5 285 8.9E-119 T 16-09-2016 Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 Gene3D G3DSA:1.10.260.40 8 70 2.3E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04520 d988684ea3aad9d8400b0dab5dd4170f 286 SMART SM00530 15 70 2.2E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 Gene3D G3DSA:3.30.420.40 257 311 2.9E-36 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 Gene3D G3DSA:3.30.420.40 154 180 2.9E-36 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 1.5E-153 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PANTHER PTHR19375:SF117 3 320 6.5E-175 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 Pfam PF06723 MreB/Mbl protein 6 330 4.5E-156 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 SUPERFAMILY SSF53067 5 142 2.02E-42 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 4.4E-62 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 4.4E-62 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 4.4E-62 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 4.4E-62 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 4.4E-62 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 Gene3D G3DSA:3.30.420.40 6 153 7.4E-48 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 SUPERFAMILY SSF53067 144 321 1.62E-51 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 PANTHER PTHR19375 3 320 6.5E-175 T 16-09-2016 Spa2297_RS11035 0ff723e337740858945745f27b9e5628 339 Gene3D G3DSA:3.90.640.10 181 253 4.7E-32 T 16-09-2016 Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 Gene3D G3DSA:1.20.1250.20 238 411 1.6E-5 T 16-09-2016 Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 SUPERFAMILY SSF103473 19 411 2.22E-22 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 PANTHER PTHR23513:SF11 1 420 1.2E-102 T 16-09-2016 Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 Pfam PF07690 Major Facilitator Superfamily 44 380 8.1E-15 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 PANTHER PTHR23513 1 420 1.2E-102 T 16-09-2016 Spa2297_RS16480 87e434384542e842440fd0afc7d91187 420 Gene3D G3DSA:1.20.1250.20 35 195 1.6E-9 T 16-09-2016 Spa2297_RS01330 5d26e6c18813fae82622942d3fc550c5 135 PANTHER PTHR11803:SF9 1 134 3.0E-50 T 16-09-2016 Spa2297_RS01330 5d26e6c18813fae82622942d3fc550c5 135 Gene3D G3DSA:3.30.1330.40 1 135 2.9E-30 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS01330 5d26e6c18813fae82622942d3fc550c5 135 SUPERFAMILY SSF55298 4 135 4.4E-23 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS01330 5d26e6c18813fae82622942d3fc550c5 135 Pfam PF01042 Endoribonuclease L-PSP 17 134 7.2E-17 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS01330 5d26e6c18813fae82622942d3fc550c5 135 PANTHER PTHR11803 1 134 3.0E-50 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS01305 078477f863c00440f13090919feeed5d 467 Pfam PF13416 Bacterial extracellular solute-binding protein 57 373 1.9E-17 T 16-09-2016 Spa2297_RS01305 078477f863c00440f13090919feeed5d 467 Gene3D G3DSA:3.40.190.10 38 168 6.6E-17 T 16-09-2016 Spa2297_RS01305 078477f863c00440f13090919feeed5d 467 Gene3D G3DSA:3.40.190.10 169 373 2.4E-26 T 16-09-2016 Spa2297_RS01305 078477f863c00440f13090919feeed5d 467 SUPERFAMILY SSF53850 25 462 1.96E-40 T 16-09-2016 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 PANTHER PTHR15238 7 53 6.0E-21 T 16-09-2016 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 Pfam PF00471 Ribosomal protein L33 9 54 2.7E-15 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 16-09-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.173 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 SUPERFAMILY SSF57829 4 54 1.53E-16 T 16-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spa2297_RS18070 8528b51a28c1f06694023a709017e6e1 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 1.9E-21 T 16-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 419 39.474 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 SUPERFAMILY SSF46589 2 111 8.37E-24 T 16-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 SUPERFAMILY SSF55681 131 417 2.55E-84 T 16-09-2016 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 Gene3D G3DSA:1.10.287.40 2 102 4.8E-27 T 16-09-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 Gene3D G3DSA:3.30.930.10 104 418 7.7E-124 T 16-09-2016 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 414 5.1E-135 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 397 1.7E-30 T 16-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 7.9E-30 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 7.9E-30 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 7.9E-30 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 7.9E-30 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 7.9E-30 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PIRSF PIRSF001529 1 423 4.0E-142 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 7.5E-25 T 16-09-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PANTHER PTHR11778 1 423 0.0 T 16-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 Spa2297_RS16215 0b57d0d905f98465396c1f2ee9d22a59 425 PANTHER PTHR11778:SF8 1 423 0.0 T 16-09-2016 Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PANTHER PTHR24320:SF80 1 189 1.3E-30 T 16-09-2016 Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 SUPERFAMILY SSF51735 1 203 2.1E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 Gene3D G3DSA:3.40.50.720 6 199 1.5E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 Pfam PF00106 short chain dehydrogenase 7 193 1.8E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31500 d4b39f2797d12c0eff0476bac8d25989 254 PANTHER PTHR24320 1 189 1.3E-30 T 16-09-2016 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 Pfam PF00924 Mechanosensitive ion channel 126 330 1.2E-47 T 16-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 SUPERFAMILY SSF82861 84 167 1.2E-12 T 16-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 Gene3D G3DSA:3.30.70.100 243 328 8.3E-13 T 16-09-2016 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 SUPERFAMILY SSF50182 168 234 2.29E-15 T 16-09-2016 IPR010920 LSM domain Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 PANTHER PTHR30566 5 343 3.9E-78 T 16-09-2016 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 Gene3D G3DSA:2.30.30.60 185 234 6.9E-17 T 16-09-2016 Spa2297_RS28615 d0667e8fa160669131c4b96fe01b812c 354 SUPERFAMILY SSF82689 242 341 3.14E-17 T 16-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 SUPERFAMILY SSF56176 5 178 4.64E-35 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 Pfam PF01565 FAD binding domain 35 149 9.5E-22 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 Gene3D G3DSA:3.30.43.10 4 71 1.1E-10 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 Pfam PF04030 D-arabinono-1,4-lactone oxidase 288 413 4.8E-20 T 16-09-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 PANTHER PTHR13878:SF5 1 417 1.2E-81 T 16-09-2016 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 Gene3D G3DSA:3.30.465.10 72 178 6.2E-27 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS25995 81cb093cb0c5a0b6660debf6d796d939 418 PANTHER PTHR13878 1 417 1.2E-81 T 16-09-2016 Spa2297_RS24420 66ef0b7823b71fff8cf33b2d6f2b1f47 179 Gene3D G3DSA:2.60.120.10 43 161 2.2E-15 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS24420 66ef0b7823b71fff8cf33b2d6f2b1f47 179 Pfam PF05995 Cysteine dioxygenase type I 16 162 3.1E-48 T 16-09-2016 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|UniPathway: UPA00012 Spa2297_RS24420 66ef0b7823b71fff8cf33b2d6f2b1f47 179 PANTHER PTHR12918 43 172 1.7E-31 T 16-09-2016 Spa2297_RS24420 66ef0b7823b71fff8cf33b2d6f2b1f47 179 SUPERFAMILY SSF51182 15 167 8.19E-27 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 PANTHER PTHR30061 1 425 9.7E-105 T 16-09-2016 Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 Pfam PF01547 Bacterial extracellular solute-binding protein 49 336 1.3E-39 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 PANTHER PTHR30061:SF24 1 425 9.7E-105 T 16-09-2016 Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 Gene3D G3DSA:3.40.190.10 166 355 7.9E-35 T 16-09-2016 Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 Gene3D G3DSA:3.40.190.10 40 165 1.5E-23 T 16-09-2016 Spa2297_RS22140 be32039e5eaedbba84e2d0a6faf41d63 425 SUPERFAMILY SSF53850 38 418 3.04E-68 T 16-09-2016 Spa2297_RS23960 3c78d67a59684b73fb31b77df7c92c4c 216 SUPERFAMILY SSF52833 1 207 2.24E-34 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS23960 3c78d67a59684b73fb31b77df7c92c4c 216 PANTHER PTHR13887:SF10 1 207 2.3E-40 T 16-09-2016 Spa2297_RS23960 3c78d67a59684b73fb31b77df7c92c4c 216 Gene3D G3DSA:3.40.30.10 1 193 2.0E-36 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS23960 3c78d67a59684b73fb31b77df7c92c4c 216 Pfam PF01323 DSBA-like thioredoxin domain 2 192 1.8E-31 T 16-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Spa2297_RS23960 3c78d67a59684b73fb31b77df7c92c4c 216 PANTHER PTHR13887 1 207 2.3E-40 T 16-09-2016 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 339 2.4E-26 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 SUPERFAMILY SSF52540 22 272 1.74E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 PANTHER PTHR24220:SF336 24 345 4.6E-166 T 16-09-2016 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 Pfam PF00005 ABC transporter 50 200 6.4E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 SMART SM00382 58 250 3.2E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 320 2.9E-16 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 PANTHER PTHR24220 24 345 4.6E-166 T 16-09-2016 Spa2297_RS23175 9d1c43419ffa92415e91dd0862cafb31 463 Gene3D G3DSA:3.40.50.300 21 274 6.0E-79 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26910 47a4f85f533825934479ab522145f7f8 218 PANTHER PTHR35809 10 217 3.5E-67 T 16-09-2016 Spa2297_RS26910 47a4f85f533825934479ab522145f7f8 218 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 33 217 6.0E-54 T 16-09-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 Spa2297_RS26910 47a4f85f533825934479ab522145f7f8 218 Pfam PF02666 Phosphatidylserine decarboxylase 59 212 3.1E-31 T 16-09-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 Spa2297_RS26910 47a4f85f533825934479ab522145f7f8 218 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 17 218 32.638 T 16-09-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Gene3D G3DSA:1.10.730.10 638 815 9.6E-49 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 2 829 8.2E-271 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 620 3.7E-168 T 16-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 1 1037 13.855 T 16-09-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 SUPERFAMILY SSF52374 386 640 5.63E-124 T 16-09-2016 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 SUPERFAMILY SSF52374 2 194 5.63E-124 T 16-09-2016 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Gene3D G3DSA:3.90.740.10 221 389 4.3E-53 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 SUPERFAMILY SSF47323 647 885 1.25E-48 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PANTHER PTHR11946 1 241 0.0 T 16-09-2016 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PANTHER PTHR11946 261 927 0.0 T 16-09-2016 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Gene3D G3DSA:3.40.50.620 2 190 1.5E-137 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Gene3D G3DSA:3.40.50.620 390 627 1.5E-137 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 SUPERFAMILY SSF50677 197 386 2.41E-46 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 37 48 1.6E-26 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 1.6E-26 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 511 524 1.6E-26 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 551 560 1.6E-26 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 1.6E-26 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PANTHER PTHR11946:SF87 1 241 0.0 T 16-09-2016 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 Pfam PF08264 Anticodon-binding domain of tRNA 679 824 4.4E-31 T 16-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 Spa2297_RS08485 913dad4039f82bc270959ad4b4c87780 1039 PANTHER PTHR11946:SF87 261 927 0.0 T 16-09-2016 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 Gene3D G3DSA:3.30.860.10 1 92 1.7E-41 T 16-09-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 SUPERFAMILY SSF54570 3 84 2.75E-35 T 16-09-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 PANTHER PTHR11880 1 92 1.3E-53 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-24 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-24 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-24 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 16-09-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.4E-47 T 16-09-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 PIRSF PIRSF002144 1 93 6.4E-32 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 Pfam PF00203 Ribosomal protein S19 3 83 2.0E-37 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19815 9f323847c57aa526e36dd7d4859ef301 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.144 T 16-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 PANTHER PTHR30055 2 228 4.7E-78 T 16-09-2016 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.1E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.1E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 Gene3D G3DSA:1.10.10.60 2 44 1.1E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 SUPERFAMILY SSF46689 2 51 4.4E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 Gene3D G3DSA:1.10.357.10 45 186 1.1E-26 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 46 2.8E-17 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 48 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS26940 76292c62ed74de2ff309c724482c0b92 240 PANTHER PTHR30055:SF80 2 228 4.7E-78 T 16-09-2016 Spa2297_RS28895 b102c969e9f07c6884f5b13ccd97cca0 446 Pfam PF01547 Bacterial extracellular solute-binding protein 69 353 4.7E-43 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS28895 b102c969e9f07c6884f5b13ccd97cca0 446 Gene3D G3DSA:3.40.190.10 57 226 1.7E-35 T 16-09-2016 Spa2297_RS28895 b102c969e9f07c6884f5b13ccd97cca0 446 SUPERFAMILY SSF53850 37 444 4.2E-65 T 16-09-2016 Spa2297_RS28895 b102c969e9f07c6884f5b13ccd97cca0 446 PANTHER PTHR30061:SF24 1 445 1.4E-117 T 16-09-2016 Spa2297_RS28895 b102c969e9f07c6884f5b13ccd97cca0 446 PANTHER PTHR30061 1 445 1.4E-117 T 16-09-2016 Spa2297_RS34065 b66ddf957fc9401d79c4086bf4d7d5c8 102 Pfam PF03741 Integral membrane protein TerC family 1 102 2.8E-11 T 16-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 Spa2297_RS34065 b66ddf957fc9401d79c4086bf4d7d5c8 102 PANTHER PTHR30238:SF0 1 102 3.2E-30 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS34065 b66ddf957fc9401d79c4086bf4d7d5c8 102 PANTHER PTHR30238 1 102 3.2E-30 T 16-09-2016 Spa2297_RS07530 d85888a22b70498e20a606c62b33ed2b 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 300 6.9E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07530 d85888a22b70498e20a606c62b33ed2b 311 PANTHER PTHR30406:SF2 1 311 3.6E-116 T 16-09-2016 Spa2297_RS07530 d85888a22b70498e20a606c62b33ed2b 311 PANTHER PTHR30406 1 311 3.6E-116 T 16-09-2016 Spa2297_RS07530 d85888a22b70498e20a606c62b33ed2b 311 SUPERFAMILY SSF161098 70 298 9.81E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07530 d85888a22b70498e20a606c62b33ed2b 311 Gene3D G3DSA:1.10.3720.10 18 300 4.3E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 384 403 4.5E-6 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 4.5E-6 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 341 356 4.5E-6 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 63 402 1.6E-60 T 16-09-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 Gene3D G3DSA:3.40.640.10 90 355 9.3E-94 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 Gene3D G3DSA:1.20.1650.10 4 79 1.3E-23 T 16-09-2016 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 Gene3D G3DSA:3.90.1150.10 356 471 6.4E-42 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 PANTHER PTHR11999 1 472 4.0E-295 T 16-09-2016 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 PANTHER PTHR11999:SF87 1 472 4.0E-295 T 16-09-2016 Spa2297_RS11785 3fc4cf4991084b9bddd957d5e5485c9b 480 SUPERFAMILY SSF53383 22 470 9.6E-117 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PANTHER PTHR13779:SF20 62 600 1.9E-232 T 16-09-2016 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 SUPERFAMILY SSF48452 158 250 1.06E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 SUPERFAMILY SSF48452 12 46 1.06E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 SMART SM00382 374 515 2.2E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 Gene3D G3DSA:1.25.40.10 176 256 1.1E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 Gene3D G3DSA:1.25.40.10 18 52 1.1E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 Gene3D G3DSA:3.40.50.300 337 512 1.4E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PANTHER PTHR13779 62 600 1.9E-232 T 16-09-2016 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 483 500 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 429 448 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 560 572 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 500 519 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 337 351 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 462 474 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 415 429 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 PRINTS PR00819 CbxX/CfqX superfamily signature 377 392 9.1E-51 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 SUPERFAMILY SSF52540 338 582 9.18E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05390 edeee94017d4d318d54cd7ed018a3e51 618 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 379 512 1.6E-14 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS23940 c3527b3a832be675432785dea3f9409a 305 SUPERFAMILY SSF51735 7 251 1.53E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23940 c3527b3a832be675432785dea3f9409a 305 PANTHER PTHR14194 7 302 7.8E-50 T 16-09-2016 Spa2297_RS23940 c3527b3a832be675432785dea3f9409a 305 Gene3D G3DSA:3.40.50.720 7 229 1.3E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23940 c3527b3a832be675432785dea3f9409a 305 Pfam PF05368 NmrA-like family 9 230 2.5E-27 T 16-09-2016 IPR008030 NmrA-like domain Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 Gene3D G3DSA:3.40.50.720 15 251 1.9E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PANTHER PTHR24322 167 198 3.7E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PANTHER PTHR24322 20 151 3.7E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 SUPERFAMILY SSF51735 16 243 5.83E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.9E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.9E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.9E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 3.5E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.5E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 3.5E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.5E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 3.5E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09545 e56019224809bf7e9171a27ca00e4ac6 262 Pfam PF00106 short chain dehydrogenase 16 208 1.0E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 Gene3D G3DSA:2.30.42.10 269 357 1.2E-18 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PANTHER PTHR22939 49 358 1.3E-98 T 16-09-2016 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 Pfam PF13365 Trypsin-like peptidase domain 80 224 4.2E-28 T 16-09-2016 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PANTHER PTHR22939:SF77 49 358 1.3E-98 T 16-09-2016 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 Pfam PF13180 PDZ domain 271 355 2.3E-17 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 SMART SM00228 270 346 1.6E-6 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 217 234 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 304 316 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 111 131 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 195 212 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 89 101 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 PRINTS PR00834 HtrA/DegQ protease family signature 153 177 6.0E-37 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 SUPERFAMILY SSF50156 270 357 6.7E-18 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 SUPERFAMILY SSF50494 56 264 6.89E-51 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 Gene3D G3DSA:2.40.10.10 72 153 1.3E-22 T 16-09-2016 Spa2297_RS08965 ad47f37b681960d3479c527c69aa7b49 358 Gene3D G3DSA:2.40.10.10 154 265 1.8E-36 T 16-09-2016 Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 SUPERFAMILY SSF52540 4 216 9.3E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 Gene3D G3DSA:3.40.50.300 4 216 3.3E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 PANTHER PTHR24220:SF160 5 232 1.0E-86 T 16-09-2016 Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 PANTHER PTHR24220 5 232 1.0E-86 T 16-09-2016 Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 Pfam PF00005 ABC transporter 20 157 3.1E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS16235 6d41be97fc37930fd00ac2eda55261f0 303 SMART SM00382 27 224 1.8E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 PANTHER PTHR31155 18 318 7.8E-194 T 16-09-2016 Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 SUPERFAMILY SSF47240 5 318 4.47E-82 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 PIRSF PIRSF000346 1 322 1.1E-115 T 16-09-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 Pfam PF03405 Fatty acid desaturase 18 316 2.8E-75 T 16-09-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 PANTHER PTHR31155:SF5 18 318 7.8E-194 T 16-09-2016 Spa2297_RS27960 7519d26da5c1a2af6c469e7363f63e51 324 Gene3D G3DSA:1.10.620.20 7 313 3.7E-108 T 16-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 208 2.1E-21 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 Gene3D G3DSA:3.40.50.720 400 674 3.5E-63 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 Gene3D G3DSA:3.40.225.10 6 212 3.7E-30 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PANTHER PTHR24322 425 600 7.8E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 422 439 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 506 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 637 657 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 590 607 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 569 588 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 543 559 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 427 673 9.3E-48 T 16-09-2016 Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 SMART SM01007 9 211 4.1E-33 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 SUPERFAMILY SSF53639 7 212 1.04E-29 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 8 679 0.0 T 16-09-2016 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- Spa2297_RS29645 88a81f2cb8be67e835bb92dee5cb4ff1 679 SUPERFAMILY SSF51735 410 676 5.44E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 Gene3D G3DSA:1.10.3860.10 16 414 1.8E-109 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 Pfam PF00375 Sodium:dicarboxylate symporter family 23 410 1.1E-111 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 238 257 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 63 83 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 366 386 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 93 118 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 305 331 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PRINTS PR00173 Glutamate-aspartate symporter signature 340 359 2.3E-29 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PANTHER PTHR11958 13 440 6.3E-228 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 PANTHER PTHR11958:SF59 13 440 6.3E-228 T 16-09-2016 Spa2297_RS18875 0e0750fdbb6fc9a60f046bd6b28e1987 446 SUPERFAMILY SSF118215 23 411 4.32E-103 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 290 4.6E-42 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 Gene3D G3DSA:1.20.1510.10 8 218 3.1E-34 T 16-09-2016 IPR027469 Cation efflux protein transmembrane domain Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 Gene3D G3DSA:3.30.70.1350 220 298 9.7E-8 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 SUPERFAMILY SSF160240 222 295 9.55E-9 T 16-09-2016 Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 PANTHER PTHR13414 1 262 2.6E-94 T 16-09-2016 Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 Pfam PF01545 Cation efflux family 11 218 9.1E-36 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS13090 1da5942da674ec89243d573c29bfeb26 326 SUPERFAMILY SSF161111 6 219 4.71E-39 T 16-09-2016 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.5E-16 T 16-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.5E-16 T 16-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.5E-16 T 16-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 SUPERFAMILY SSF143034 2 63 1.44E-20 T 16-09-2016 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 Pfam PF01632 Ribosomal protein L35 2 62 2.5E-23 T 16-09-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 16-09-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 4.1E-25 T 16-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 PANTHER PTHR33343 1 62 1.7E-22 T 16-09-2016 Spa2297_RS06165 3977af132ecf9f19bdac9a7ee33ac615 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.567 T 16-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 SMART SM00393 92 170 2.3E-28 T 16-09-2016 IPR001374 R3H domain GO:0003676 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 Gene3D G3DSA:3.30.300.120 20 102 1.1E-21 T 16-09-2016 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 PANTHER PTHR20953:SF0 1 170 4.3E-115 T 16-09-2016 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 Pfam PF01424 R3H domain 112 167 9.8E-16 T 16-09-2016 IPR001374 R3H domain GO:0003676 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 SUPERFAMILY SSF82708 123 169 1.12E-11 T 16-09-2016 IPR001374 R3H domain GO:0003676 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 Gene3D G3DSA:3.30.1370.50 103 169 4.1E-24 T 16-09-2016 IPR001374 R3H domain GO:0003676 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 PANTHER PTHR20953 1 170 4.3E-115 T 16-09-2016 Spa2297_RS16555 10e6881b1bf937b888bb18f7c6fe247a 170 Pfam PF13083 KH domain 27 97 2.2E-7 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 SUPERFAMILY SSF101821 92 211 1.92E-30 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 Gene3D G3DSA:2.30.250.10 91 218 7.0E-38 T 16-09-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 113 133 2.5E-37 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 397 412 2.5E-37 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 80 96 2.5E-37 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 308 324 2.5E-37 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 265 283 2.5E-37 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 Gene3D G3DSA:3.40.630.10 221 431 1.6E-102 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 Gene3D G3DSA:3.40.630.10 11 90 1.6E-102 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 429 9.7E-123 T 16-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 SUPERFAMILY SSF53187 10 91 9.87E-93 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 SUPERFAMILY SSF53187 212 431 9.87E-93 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PANTHER PTHR28570:SF5 13 431 3.9E-167 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 PANTHER PTHR28570 13 431 3.9E-167 T 16-09-2016 Spa2297_RS16935 0d962af76ce42e3fadf90bb838a21a33 432 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 432 59.272 T 16-09-2016 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 2.2E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 SMART SM00421 154 211 2.2E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 PANTHER PTHR26402 3 217 5.2E-92 T 16-09-2016 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 Gene3D G3DSA:3.40.50.2300 2 156 1.5E-37 T 16-09-2016 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 PANTHER PTHR26402:SF151 3 217 5.2E-92 T 16-09-2016 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 9.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 9.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 9.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 SUPERFAMILY SSF46894 150 217 3.27E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 SUPERFAMILY SSF52172 1 125 1.35E-31 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 Gene3D G3DSA:1.10.10.10 157 215 2.9E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 SMART SM00448 3 117 7.9E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS04605 53882fd52d7d4c7a67a28c4fb80fc7bd 220 Pfam PF00072 Response regulator receiver domain 5 118 1.8E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS28620 c629bbe5e214284cffa2b16271d9aaf3 514 Pfam PF13520 Amino acid permease 42 477 3.4E-61 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28620 c629bbe5e214284cffa2b16271d9aaf3 514 PANTHER PTHR11785:SF286 5 511 7.5E-181 T 16-09-2016 Spa2297_RS28620 c629bbe5e214284cffa2b16271d9aaf3 514 PANTHER PTHR11785 5 511 7.5E-181 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28620 c629bbe5e214284cffa2b16271d9aaf3 514 ProSitePatterns PS00218 Amino acid permeases signature. 69 100 - T 16-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 Spa2297_RS28620 c629bbe5e214284cffa2b16271d9aaf3 514 PIRSF PIRSF006060 18 510 1.3E-62 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PANTHER PTHR30023 38 450 4.8E-81 T 16-09-2016 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 334 348 1.0E-26 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 262 284 1.0E-26 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 403 416 1.0E-26 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 319 333 1.0E-26 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 116 135 1.0E-26 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 77 222 2.4E-39 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 223 444 7.7E-78 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 PANTHER PTHR30023:SF0 38 450 4.8E-81 T 16-09-2016 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 SUPERFAMILY SSF56601 81 449 2.62E-62 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 224 425 1.7E-46 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 Gene3D G3DSA:3.40.710.10 224 448 8.2E-59 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS26795 dea1a06bfa007dcb8f1d5d02b4a05c05 450 Gene3D G3DSA:3.40.710.10 98 154 1.3E-5 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 Gene3D G3DSA:3.40.50.720 236 464 1.2E-68 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 Gene3D G3DSA:3.40.50.10380 93 235 1.8E-55 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 SUPERFAMILY SSF51735 238 469 3.54E-67 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PIRSF PIRSF000106 73 471 8.4E-82 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PRINTS PR00072 Malic enzyme signature 265 281 1.6E-11 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PRINTS PR00072 Malic enzyme signature 358 374 1.6E-11 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PRINTS PR00072 Malic enzyme signature 155 177 1.6E-11 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PRINTS PR00072 Malic enzyme signature 234 250 1.6E-11 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 9.6E-31 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 SMART SM01274 93 226 3.1E-85 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 Pfam PF03949 Malic enzyme, NAD binding domain 240 464 2.0E-21 T 16-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 SUPERFAMILY SSF53223 87 236 4.17E-57 T 16-09-2016 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PANTHER PTHR23406 52 469 2.7E-169 T 16-09-2016 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 PANTHER PTHR23406:SF23 52 469 2.7E-169 T 16-09-2016 Spa2297_RS12750 13fb8ea69703de19946d2eea28b5cf93 471 SMART SM00919 238 465 1.6E-109 T 16-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Pfam PF00005 ABC transporter 313 460 1.6E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SMART SM00240 207 258 6.4E-14 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SMART SM00240 24 74 1.0E-10 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Gene3D G3DSA:2.60.200.20 147 298 5.4E-24 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SUPERFAMILY SSF49879 156 303 1.57E-28 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SUPERFAMILY SSF49879 13 89 6.12E-22 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Gene3D G3DSA:2.60.200.20 13 89 2.5E-22 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SUPERFAMILY SSF52540 290 531 3.82E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 PANTHER PTHR19241 281 803 3.7E-98 T 16-09-2016 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 13 89 4.0E-16 T 16-09-2016 IPR032030 YscD, cytoplasmic domain Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Pfam PF00498 FHA domain 209 275 1.2E-15 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Gene3D G3DSA:3.40.50.300 299 522 7.3E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 Pfam PF01061 ABC-2 type transporter 586 803 5.6E-15 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 SMART SM00382 322 516 6.6E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07175 e5eb3600162f28770fe9ea97bc21f8ae 865 PANTHER PTHR19241:SF189 281 803 3.7E-98 T 16-09-2016 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SUPERFAMILY SSF68912 39 79 3.84E-5 T 16-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Gene3D G3DSA:3.40.50.300 386 669 3.0E-99 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SMART SM00382 422 607 2.7E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SMART SM00357 307 373 3.8E-10 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SUPERFAMILY SSF52540 344 622 6.26E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 PANTHER PTHR15184 232 668 2.0E-170 T 16-09-2016 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SMART SM00959 39 80 1.9E-11 T 16-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Pfam PF07498 Rho termination factor, N-terminal domain 40 80 1.2E-11 T 16-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Hamap MF_01884 Transcription termination factor Rho [rho]. 299 671 204.123 T 16-09-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 TIGRFAM TIGR00767 rho: transcription termination factor Rho 40 669 4.8E-199 T 16-09-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 PANTHER PTHR15184:SF34 232 668 2.0E-170 T 16-09-2016 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 SUPERFAMILY SSF50249 306 380 8.22E-17 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Pfam PF07497 Rho termination factor, RNA-binding domain 306 380 3.9E-29 T 16-09-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 411 615 1.2E-20 T 16-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Gene3D G3DSA:2.40.50.140 40 79 1.9E-41 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS22615 54c18e4312e7dc4a2e76b1a1703b2000 679 Gene3D G3DSA:2.40.50.140 301 380 1.9E-41 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 Gene3D G3DSA:3.40.50.1980 30 243 6.9E-76 T 16-09-2016 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 432 1.9E-139 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 16-09-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 433 38.502 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PANTHER PTHR21256 17 439 7.0E-185 T 16-09-2016 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 SUPERFAMILY SSF53720 19 435 7.45E-70 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PIRSF PIRSF000099 5 436 3.8E-162 T 16-09-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 Pfam PF00815 Histidinol dehydrogenase 24 433 3.0E-153 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS08380 df4d5bc8bb7d88125dd71ee11f5f348d 441 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 1.6E-81 T 16-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:1.10.1200.10 2033 2095 4.6E-21 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:1.10.1200.10 980 1043 6.5E-27 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 1061 1231 8.56E-48 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00550 Phosphopantetheine attachment site 2031 2091 1.6E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00550 Phosphopantetheine attachment site 978 1040 1.0E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 PANTHER PTHR24095:SF137 9 2002 0.0 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF47336 968 1040 1.28E-20 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 PANTHER PTHR24095 9 2002 0.0 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.40.50.980 1521 1689 1.6E-46 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.40.50.980 456 609 2.7E-49 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00501 AMP-binding enzyme 462 869 1.0E-102 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00501 AMP-binding enzyme 1526 1921 8.7E-96 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.40.50.980 1690 1831 2.2E-36 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.30.300.30 864 979 3.1E-41 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.30.300.30 1916 2032 6.6E-40 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF13193 AMP-binding enzyme C-terminal domain 877 950 3.3E-15 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF13193 AMP-binding enzyme C-terminal domain 1929 2002 3.1E-14 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF13745 HxxPF-repeated domain 1377 1471 4.8E-29 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2053 2068 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:2.30.38.10 779 859 4.2E-25 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:2.30.38.10 1832 1911 9.1E-27 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 2301 2574 4.34E-32 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1547 1945 4.2E-130 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 892 3.8E-143 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2436 2598 7.3E-37 T 16-09-2016 IPR010060 Non-ribosomal peptide synthase Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1666 1677 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 192 426 6.34E-35 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SMART SM00823 Phosphopantetheine attachment site 2029 2097 0.008 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SMART SM00823 Phosphopantetheine attachment site 975 1044 6.6E-11 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF56801 1485 2042 1.83E-153 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF47336 2022 2091 1.31E-15 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 1244 1490 6.67E-63 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 2112 2310 2.82E-27 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Gene3D G3DSA:3.40.50.980 610 773 1.3E-48 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF56801 450 988 4.06E-166 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 SUPERFAMILY SSF52777 12 186 4.0E-32 T 16-09-2016 Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00668 Condensation domain 7 301 4.9E-41 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00668 Condensation domain 1059 1355 6.7E-64 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 Pfam PF00668 Condensation domain 2129 2421 2.7E-29 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS02685 ef647dd805d0b49fd1bb7458281fdf96 2606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 999 1014 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS02115 ed7179b5fa9ebdbd84abd7458188d1d4 142 SUPERFAMILY SSF55874 36 141 3.31E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02115 ed7179b5fa9ebdbd84abd7458188d1d4 142 Gene3D G3DSA:3.30.565.10 45 141 4.1E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 SUPERFAMILY SSF53383 109 475 8.57E-82 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 Gene3D G3DSA:3.90.1150.10 367 469 1.7E-17 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 66 1.8E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.7E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.7E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 PANTHER PTHR11751 94 477 2.5E-144 T 16-09-2016 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 SUPERFAMILY SSF46785 19 71 2.41E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 Pfam PF00155 Aminotransferase class I and II 129 467 3.0E-25 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 SMART SM00345 10 67 4.9E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 Gene3D G3DSA:1.10.10.10 19 70 1.3E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 Gene3D G3DSA:3.40.640.10 150 362 8.0E-53 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS06100 7efcd8c030a7dad391bf7420a6ab21c6 487 PANTHER PTHR11751:SF119 94 477 2.5E-144 T 16-09-2016 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 Pfam PF00248 Aldo/keto reductase family 18 258 9.3E-50 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.5E-44 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.5E-44 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.5E-44 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.5E-44 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.5E-44 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 PANTHER PTHR11732 4 257 1.2E-133 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 SUPERFAMILY SSF51430 7 261 1.7E-89 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 Gene3D G3DSA:3.20.20.100 6 261 1.1E-98 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01915 5e9fd513cc08a7718925602cc738220d 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 PANTHER PTHR30346:SF8 27 310 7.3E-140 T 16-09-2016 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 PANTHER PTHR30346 27 310 7.3E-140 T 16-09-2016 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 Gene3D G3DSA:3.40.190.10 112 197 1.8E-22 T 16-09-2016 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 Gene3D G3DSA:3.40.190.10 198 285 2.3E-32 T 16-09-2016 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 Pfam PF03466 LysR substrate binding domain 110 310 1.1E-50 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 2.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 2.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 SUPERFAMILY SSF53850 111 314 4.89E-45 T 16-09-2016 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 SUPERFAMILY SSF46785 28 106 9.48E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 84 1.4E-17 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20730 4fdd6c79e92a6f57444b2e7716b9d87d 317 Gene3D G3DSA:1.10.10.10 27 107 2.7E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29395 da866de24f19e4a3f3a53e378f860cd8 217 Gene3D G3DSA:2.30.110.10 32 164 4.3E-19 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29395 da866de24f19e4a3f3a53e378f860cd8 217 SUPERFAMILY SSF50475 36 172 7.64E-14 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29395 da866de24f19e4a3f3a53e378f860cd8 217 PANTHER PTHR30212:SF3 14 197 1.6E-31 T 16-09-2016 Spa2297_RS29395 da866de24f19e4a3f3a53e378f860cd8 217 PANTHER PTHR30212 14 197 1.6E-31 T 16-09-2016 Spa2297_RS29395 da866de24f19e4a3f3a53e378f860cd8 217 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 134 1.2E-10 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS09655 6f7c37b1d064b3e9cb463ebdf237fd54 481 Pfam PF07690 Major Facilitator Superfamily 31 144 1.3E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09655 6f7c37b1d064b3e9cb463ebdf237fd54 481 PANTHER PTHR23501:SF76 2 149 3.0E-69 T 16-09-2016 Spa2297_RS09655 6f7c37b1d064b3e9cb463ebdf237fd54 481 Gene3D G3DSA:1.20.1250.20 22 145 1.1E-21 T 16-09-2016 Spa2297_RS09655 6f7c37b1d064b3e9cb463ebdf237fd54 481 SUPERFAMILY SSF103473 14 144 8.89E-30 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09655 6f7c37b1d064b3e9cb463ebdf237fd54 481 PANTHER PTHR23501 2 149 3.0E-69 T 16-09-2016 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 PANTHER PTHR22749 1 311 7.8E-129 T 16-09-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 SUPERFAMILY SSF52374 16 179 8.59E-31 T 16-09-2016 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 Gene3D G3DSA:3.40.50.620 3 183 1.9E-61 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 PANTHER PTHR22749:SF0 1 311 7.8E-129 T 16-09-2016 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 Pfam PF06574 FAD synthetase 12 158 1.4E-50 T 16-09-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 311 7.2E-65 T 16-09-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 Pfam PF01687 Riboflavin kinase 188 310 4.2E-32 T 16-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 SMART SM00904 187 312 2.7E-48 T 16-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 Gene3D G3DSA:2.40.30.30 184 314 3.1E-43 T 16-09-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 PIRSF PIRSF004491 1 318 3.1E-94 T 16-09-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 Spa2297_RS24185 2eef53d9abb815fe16bec8715a26adb0 319 SUPERFAMILY SSF82114 178 313 4.58E-41 T 16-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 25 171 1.4E-26 T 16-09-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 171 12.227 T 16-09-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 Pfam PF00430 ATP synthase B/B' CF(0) 23 150 2.3E-28 T 16-09-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 Gene3D G3DSA:1.20.5.620 77 136 2.4E-11 T 16-09-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 SUPERFAMILY SSF81573 77 135 2.75E-10 T 16-09-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain Spa2297_RS22680 2bd9f2155a667a8fc114ece9f03e8212 182 PANTHER PTHR33445 1 177 1.3E-44 T 16-09-2016 Spa2297_RS04135 4b8973e45bcf26fa68e064645724aecb 137 PANTHER PTHR36222 1 137 1.5E-46 T 16-09-2016 Spa2297_RS04135 4b8973e45bcf26fa68e064645724aecb 137 Pfam PF03259 Roadblock/LC7 domain 8 97 7.2E-27 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS04135 4b8973e45bcf26fa68e064645724aecb 137 SUPERFAMILY SSF103196 5 127 1.12E-34 T 16-09-2016 Spa2297_RS04135 4b8973e45bcf26fa68e064645724aecb 137 SMART SM00960 8 98 6.9E-30 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS04135 4b8973e45bcf26fa68e064645724aecb 137 Gene3D G3DSA:3.30.450.30 5 123 4.1E-26 T 16-09-2016 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 PANTHER PTHR19211 277 532 2.5E-240 T 16-09-2016 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 SUPERFAMILY SSF52540 340 531 1.58E-35 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 PANTHER PTHR19211:SF6 2 251 2.5E-240 T 16-09-2016 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 SUPERFAMILY SSF52540 16 220 5.58E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 Pfam PF00005 ABC transporter 357 482 9.6E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 Pfam PF00005 ABC transporter 32 170 9.9E-21 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 Gene3D G3DSA:3.40.50.300 339 532 3.9E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 Gene3D G3DSA:3.40.50.300 6 253 3.7E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 PANTHER PTHR19211:SF6 277 532 2.5E-240 T 16-09-2016 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 PANTHER PTHR19211 2 251 2.5E-240 T 16-09-2016 Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 SMART SM00382 29 214 3.4E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27975 a36a5a063b67a1b50b087388ec0c12fb 541 SMART SM00382 361 533 3.0E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 Pfam PF01145 SPFH domain / Band 7 family 29 219 9.6E-22 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 Pfam PF15975 Flotillin 377 460 6.5E-12 T 16-09-2016 IPR031905 Flotillin, C-terminal domain Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 PANTHER PTHR13806:SF20 379 489 2.1E-129 T 16-09-2016 Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 PANTHER PTHR13806 1 336 2.1E-129 T 16-09-2016 IPR027705 Flotillin family Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 SUPERFAMILY SSF117892 71 210 7.72E-26 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 PANTHER PTHR13806 379 489 2.1E-129 T 16-09-2016 IPR027705 Flotillin family Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 SMART SM00244 24 205 0.0013 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS17785 d8595d3ba0af8842f329f19610f3c320 516 PANTHER PTHR13806:SF20 1 336 2.1E-129 T 16-09-2016 Spa2297_RS18770 255e1fcd95c4052e5bd204458aaaf9fa 215 Pfam PF01966 HD domain 34 120 1.0E-7 T 16-09-2016 IPR006674 HD domain Spa2297_RS18770 255e1fcd95c4052e5bd204458aaaf9fa 215 Gene3D G3DSA:1.10.3210.10 23 141 6.3E-11 T 16-09-2016 IPR006674 HD domain Spa2297_RS18770 255e1fcd95c4052e5bd204458aaaf9fa 215 SUPERFAMILY SSF109604 20 138 7.22E-17 T 16-09-2016 Spa2297_RS18770 255e1fcd95c4052e5bd204458aaaf9fa 215 PANTHER PTHR35569 9 215 3.2E-79 T 16-09-2016 Spa2297_RS18770 255e1fcd95c4052e5bd204458aaaf9fa 215 PANTHER PTHR35569:SF1 9 215 3.2E-79 T 16-09-2016 Spa2297_RS07795 e9c3b7d3d0af39760a177bf9b52d5670 285 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 51 73 - T 16-09-2016 IPR030470 UbiA prenyltransferase conserved site Spa2297_RS07795 e9c3b7d3d0af39760a177bf9b52d5670 285 PANTHER PTHR11048 3 285 4.5E-75 T 16-09-2016 Spa2297_RS07795 e9c3b7d3d0af39760a177bf9b52d5670 285 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 283 18.384 T 16-09-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 Spa2297_RS07795 e9c3b7d3d0af39760a177bf9b52d5670 285 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 2 281 7.2E-95 T 16-09-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 Spa2297_RS07795 e9c3b7d3d0af39760a177bf9b52d5670 285 Pfam PF01040 UbiA prenyltransferase family 12 267 3.2E-66 T 16-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 Gene3D G3DSA:3.30.450.40 237 396 5.6E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 PANTHER PTHR21021 371 495 1.4E-48 T 16-09-2016 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 445 658 2.4E-42 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 SUPERFAMILY SSF55781 266 397 7.36E-7 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 PANTHER PTHR21021:SF19 371 495 1.4E-48 T 16-09-2016 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 Pfam PF13581 Histidine kinase-like ATPase domain 50 160 3.1E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 PANTHER PTHR21021:SF19 520 660 1.4E-48 T 16-09-2016 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 SMART SM00331 419 659 2.6E-36 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 PANTHER PTHR21021 520 660 1.4E-48 T 16-09-2016 Spa2297_RS10780 3dc352aa79410924367a4545dd183a51 660 SUPERFAMILY SSF55874 69 164 8.36E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30165 5b62e82639db7dc58d8d6782e746a6bf 299 PANTHER PTHR11795 1 299 1.2E-123 T 16-09-2016 Spa2297_RS30165 5b62e82639db7dc58d8d6782e746a6bf 299 PANTHER PTHR11795:SF398 1 299 1.2E-123 T 16-09-2016 Spa2297_RS30165 5b62e82639db7dc58d8d6782e746a6bf 299 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 283 1.9E-31 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 Gene3D G3DSA:3.90.1200.10 104 274 5.7E-6 T 16-09-2016 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 PANTHER PTHR12083:SF8 2 352 2.2E-130 T 16-09-2016 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 PANTHER PTHR12083:SF8 381 472 2.2E-130 T 16-09-2016 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 SUPERFAMILY SSF56112 19 278 8.31E-16 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 Pfam PF13671 AAA domain 319 464 7.2E-24 T 16-09-2016 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 SUPERFAMILY SSF52540 321 446 3.33E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 Gene3D G3DSA:3.40.50.300 320 462 2.2E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 PANTHER PTHR12083 2 352 2.2E-130 T 16-09-2016 Spa2297_RS03915 04b20fda8da7945f022d7df5eb069d44 508 PANTHER PTHR12083 381 472 2.2E-130 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Gene3D G3DSA:3.30.450.40 525 684 2.4E-24 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF13185 GAF domain 549 684 2.0E-18 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00448 1215 1329 3.3E-37 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF55781 513 684 1.4E-31 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00512 His Kinase A (phospho-acceptor) domain 772 839 3.1E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF52172 1213 1333 6.12E-38 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Gene3D G3DSA:3.40.50.2300 1089 1183 3.4E-7 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF58104 310 400 6.28E-6 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF47384 756 841 5.3E-21 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 290 342 2.8E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 106 158 5.6E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 474 526 4.1E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 14 66 0.2 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 198 250 4.0E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00304 382 434 5.4E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Gene3D G3DSA:3.40.50.2300 1210 1333 1.8E-40 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00388 771 839 1.1E-21 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00065 550 700 8.1E-9 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00672 HAMP domain 287 338 5.1E-7 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00672 HAMP domain 104 154 2.5E-6 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00672 HAMP domain 195 246 2.0E-6 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00672 HAMP domain 472 523 7.0E-7 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PANTHER PTHR24423 1214 1333 2.2E-141 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PANTHER PTHR24423 750 1053 2.2E-141 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PANTHER PTHR24423 17 44 2.2E-141 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF00072 Response regulator receiver domain 1217 1329 1.1E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF55874 828 1011 6.29E-46 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Gene3D G3DSA:3.30.565.10 826 1010 1.9E-46 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF52172 1088 1183 4.55E-7 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 887 1007 1.3E-28 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF58104 34 307 1.75E-16 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 969 987 1.5E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 934 948 1.5E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 952 962 1.5E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 PRINTS PR00344 Bacterial sensor protein C-terminal signature 993 1006 1.5E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SUPERFAMILY SSF58104 402 525 7.32E-11 T 16-09-2016 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 Gene3D G3DSA:1.10.287.130 763 825 2.1E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02045 6f513c083d37bf50970fb32391866431 1335 SMART SM00387 886 1009 4.5E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS12350 324a8a496d20727688181ecdd511eebc 452 Pfam PF04286 Protein of unknown function (DUF445) 87 449 6.9E-100 T 16-09-2016 IPR007383 Protein of unknown function DUF445 Spa2297_RS12350 324a8a496d20727688181ecdd511eebc 452 PANTHER PTHR38442 28 452 1.6E-120 T 16-09-2016 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 SUPERFAMILY SSF46689 4 80 2.49E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 PANTHER PTHR30055 5 129 1.7E-53 T 16-09-2016 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.1E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.1E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 Gene3D G3DSA:1.10.357.10 4 185 4.1E-26 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 PANTHER PTHR30055:SF8 5 129 1.7E-53 T 16-09-2016 Spa2297_RS22025 550300f2222f8c8322b4e28a92068eef 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 8.2E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 519 693 1.1E-36 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SUPERFAMILY SSF141868 711 952 9.29E-55 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 397 519 2.1E-12 T 16-09-2016 IPR000014 PAS domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SMART SM00052 704 950 1.3E-46 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SMART SM00267 512 694 3.4E-51 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 PANTHER PTHR10799 502 804 3.7E-55 T 16-09-2016 Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Gene3D G3DSA:3.20.20.450 707 955 5.1E-72 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SMART SM00091 400 466 2.0E-8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SUPERFAMILY SSF55073 528 696 4.94E-42 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Pfam PF00563 EAL domain 711 945 1.9E-50 T 16-09-2016 IPR001633 EAL domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Gene3D G3DSA:3.30.70.270 524 702 1.7E-52 T 16-09-2016 Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 SUPERFAMILY SSF55785 392 510 2.51E-17 T 16-09-2016 IPR000014 PAS domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 PANTHER PTHR10799:SF710 502 804 3.7E-55 T 16-09-2016 Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Gene3D G3DSA:3.30.450.20 393 512 3.3E-18 T 16-09-2016 Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Pfam PF00990 Diguanylate cyclase, GGDEF domain 523 689 2.4E-38 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS23325 822d5dc417172fee8bad00391f8d7dce 1022 Pfam PF08448 PAS fold 409 514 2.7E-7 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS07580 a7dfeae53357121cad5f25d5e467fe35 314 PANTHER PTHR30406 1 313 1.9E-129 T 16-09-2016 Spa2297_RS07580 a7dfeae53357121cad5f25d5e467fe35 314 SUPERFAMILY SSF161098 74 296 5.63E-54 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07580 a7dfeae53357121cad5f25d5e467fe35 314 Gene3D G3DSA:1.10.3720.10 25 299 1.8E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07580 a7dfeae53357121cad5f25d5e467fe35 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 303 9.2E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07580 a7dfeae53357121cad5f25d5e467fe35 314 PANTHER PTHR30406:SF2 1 313 1.9E-129 T 16-09-2016 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PRINTS PR00762 Chloride channel signature 318 338 2.3E-25 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PRINTS PR00762 Chloride channel signature 353 369 2.3E-25 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PRINTS PR00762 Chloride channel signature 74 91 2.3E-25 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PRINTS PR00762 Chloride channel signature 154 173 2.3E-25 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PRINTS PR00762 Chloride channel signature 371 390 2.3E-25 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 SUPERFAMILY SSF81340 3 422 1.7E-108 T 16-09-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 Gene3D G3DSA:1.10.3080.10 3 421 6.2E-93 T 16-09-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 Gene3D G3DSA:3.10.580.10 436 555 1.4E-10 T 16-09-2016 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PANTHER PTHR11689 3 493 3.2E-119 T 16-09-2016 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 Pfam PF00654 Voltage gated chloride channel 60 403 4.7E-94 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 SUPERFAMILY SSF54631 436 555 3.65E-11 T 16-09-2016 Spa2297_RS26030 3525a0df38f0fa82e25e19fb3f4a6e90 568 PANTHER PTHR11689:SF14 3 493 3.2E-119 T 16-09-2016 Spa2297_RS14530 8d67991f9cfb3a82580c0f1476dc4ba3 131 PANTHER PTHR22769 1 119 2.1E-24 T 16-09-2016 Spa2297_RS14530 8d67991f9cfb3a82580c0f1476dc4ba3 131 Pfam PF00293 NUDIX domain 8 115 2.3E-18 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS14530 8d67991f9cfb3a82580c0f1476dc4ba3 131 Gene3D G3DSA:3.90.79.10 8 116 9.1E-27 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS14530 8d67991f9cfb3a82580c0f1476dc4ba3 131 SUPERFAMILY SSF55811 6 115 2.17E-27 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 Gene3D G3DSA:3.40.50.2300 58 165 1.8E-35 T 16-09-2016 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.7E-20 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 SMART SM00354 1 71 2.8E-36 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 PANTHER PTHR30146:SF59 1 342 2.1E-222 T 16-09-2016 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 PANTHER PTHR30146 1 342 2.1E-222 T 16-09-2016 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 SUPERFAMILY SSF53822 60 330 1.7E-75 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 Gene3D G3DSA:3.40.50.2300 166 329 9.9E-55 T 16-09-2016 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 Gene3D G3DSA:1.10.260.40 2 57 3.4E-27 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.5E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.5E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 SUPERFAMILY SSF47413 1 59 8.26E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS11600 5bc7a7455cce8d51583bfa5e0f374d88 344 Pfam PF13377 Periplasmic binding protein-like domain 168 327 2.5E-36 T 16-09-2016 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 SMART SM00331 327 536 3.2E-30 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 SUPERFAMILY SSF81606 344 537 3.79E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 PANTHER PTHR21021:SF19 41 56 6.3E-45 T 16-09-2016 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 PANTHER PTHR21021:SF19 305 545 6.3E-45 T 16-09-2016 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 SUPERFAMILY SSF52172 11 160 1.85E-34 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 357 536 8.1E-43 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 PANTHER PTHR21021 41 56 6.3E-45 T 16-09-2016 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 PANTHER PTHR21021 305 545 6.3E-45 T 16-09-2016 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 SMART SM00448 12 128 8.3E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 Pfam PF00072 Response regulator receiver domain 14 128 6.8E-21 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS29225 d0292c8d1154027f39eb182049c04d8a 556 Gene3D G3DSA:3.40.50.2300 9 139 2.8E-34 T 16-09-2016 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 SMART SM00495 36 80 4.4E-7 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 Pfam PF00182 Chitinase class I 95 296 6.6E-44 T 16-09-2016 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 Gene3D G3DSA:3.30.20.10 161 215 1.0E-23 T 16-09-2016 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 PIRSF PIRSF001060 2 296 1.1E-84 T 16-09-2016 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 Gene3D G3DSA:2.10.10.20 33 78 4.8E-5 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 SUPERFAMILY SSF53955 93 296 5.91E-67 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 Gene3D G3DSA:1.10.530.10 216 296 9.2E-56 T 16-09-2016 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 Gene3D G3DSA:1.10.530.10 94 152 9.2E-56 T 16-09-2016 Spa2297_RS02355 971b3c29255d2b66818dc1f093810564 296 PANTHER PTHR22595 80 296 7.6E-92 T 16-09-2016 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 PANTHER PTHR30579:SF2 3 299 7.9E-126 T 16-09-2016 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 Gene3D G3DSA:3.40.190.10 97 196 1.0E-39 T 16-09-2016 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 PANTHER PTHR30579 3 299 7.9E-126 T 16-09-2016 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 SUPERFAMILY SSF53850 99 297 1.57E-24 T 16-09-2016 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 Gene3D G3DSA:1.10.10.10 9 88 5.2E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 SUPERFAMILY SSF46785 8 117 3.58E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 Pfam PF03466 LysR substrate binding domain 96 295 1.3E-19 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 11 298 5.5E-110 T 16-09-2016 IPR017685 HTH-type transcriptional regulator ArgP Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 2.5E-17 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS02145 50828873749e3a88b3e3cbea5baa99cd 301 Gene3D G3DSA:3.40.190.10 197 260 2.9E-4 T 16-09-2016 Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 PANTHER PTHR14969:SF20 10 200 1.2E-52 T 16-09-2016 Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 PANTHER PTHR14969 10 200 1.2E-52 T 16-09-2016 Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 SUPERFAMILY SSF48317 10 182 2.09E-34 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 Pfam PF01569 PAP2 superfamily 74 179 4.6E-19 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 Gene3D G3DSA:1.20.144.10 12 179 8.6E-31 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS15510 62b0fab6c84a5376f10fd3d66914695d 236 SMART SM00014 69 180 8.0E-13 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 SUPERFAMILY SSF51182 54 176 8.31E-12 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 PANTHER PTHR10245:SF9 3 176 2.1E-39 T 16-09-2016 Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 Gene3D G3DSA:1.10.260.40 11 98 1.4E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 SUPERFAMILY SSF47413 7 74 7.32E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 Pfam PF07883 Cupin domain 123 173 7.4E-7 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 Gene3D G3DSA:2.60.120.10 105 175 3.0E-10 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 SMART SM00530 14 69 2.2E-12 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 PANTHER PTHR10245 3 176 2.1E-39 T 16-09-2016 Spa2297_RS06250 26aa42612c7196c81240d2a7371c6449 189 Pfam PF13560 Helix-turn-helix domain 11 70 2.1E-10 T 16-09-2016 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 PANTHER PTHR10245:SF7 16 270 1.6E-93 T 16-09-2016 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 SMART SM00530 20 75 1.4E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 SUPERFAMILY SSF47413 17 71 3.56E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 Pfam PF13560 Helix-turn-helix domain 18 72 1.4E-7 T 16-09-2016 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 PANTHER PTHR10245 16 270 1.6E-93 T 16-09-2016 Spa2297_RS18370 04a4f0bf880d98dbad3f51383a3303f7 282 Gene3D G3DSA:1.10.260.40 16 71 9.8E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Pfam PF00391 PEP-utilising enzyme, mobile domain 429 511 1.1E-25 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 PANTHER PTHR22931:SF9 2 656 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 PANTHER PTHR22931:SF9 673 909 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:1.10.189.10 351 409 9.6E-24 T 16-09-2016 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 PIRSF PIRSF000853 12 909 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:3.20.20.60 558 902 2.7E-126 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 SUPERFAMILY SSF56059 11 386 3.77E-133 T 16-09-2016 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:1.20.80.30 121 207 4.6E-35 T 16-09-2016 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 SUPERFAMILY SSF51621 547 899 4.97E-112 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:3.30.470.20 253 350 6.1E-33 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 PANTHER PTHR22931 2 656 0.0 T 16-09-2016 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 PANTHER PTHR22931 673 909 0.0 T 16-09-2016 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 457 468 - T 16-09-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 545 897 1.3E-84 T 16-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 71 296 1.9E-31 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 28 81 2.1E-12 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 304 360 5.1E-9 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:3.50.30.10 410 514 4.1E-38 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 14 900 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 SUPERFAMILY SSF52009 399 520 5.36E-34 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:3.30.1490.20 14 120 1.5E-57 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS10525 7e0b1ce27c3941b69b52e0e059c60138 909 Gene3D G3DSA:3.30.1490.20 209 252 1.5E-57 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS28535 35eca70efce04c261b612a93883845c7 319 PANTHER PTHR10361 15 317 8.9E-93 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS28535 35eca70efce04c261b612a93883845c7 319 Pfam PF01758 Sodium Bile acid symporter family 54 230 5.9E-46 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 Gene3D G3DSA:3.40.50.720 39 253 1.0E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PANTHER PTHR24322:SF639 183 219 1.2E-47 T 16-09-2016 Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 170 198 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PANTHER PTHR24322 183 219 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 39 219 1.6E-4 T 16-09-2016 Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 SUPERFAMILY SSF51735 36 282 2.0E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 40 57 2.2E-25 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 202 2.2E-25 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 121 2.2E-25 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 2.2E-25 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 173 2.2E-25 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PANTHER PTHR24322:SF639 43 167 1.2E-47 T 16-09-2016 Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 Pfam PF00106 short chain dehydrogenase 40 223 2.3E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 171 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 202 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 110 121 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03790 6f38b7f19d32ab0b10a51c301eceee63 284 PANTHER PTHR24322 43 167 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238:SF3 111 158 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238:SF3 176 193 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238:SF3 244 372 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238:SF3 2 86 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238 176 193 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238 244 372 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238 2 86 6.8E-178 T 16-09-2016 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 Pfam PF04332 Protein of unknown function (DUF475) 44 361 1.0E-143 T 16-09-2016 IPR007427 Protein of unknown function DUF475 Spa2297_RS09950 0fd29a6e4ccc4c6e355a913bdf5a3c3a 378 PANTHER PTHR30238 111 158 6.8E-178 T 16-09-2016 Spa2297_RS10470 4613d904482b49cd3e612ea8b3dc512f 130 SUPERFAMILY SSF46785 9 113 1.58E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10470 4613d904482b49cd3e612ea8b3dc512f 130 Gene3D G3DSA:1.10.10.10 9 107 2.0E-41 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10470 4613d904482b49cd3e612ea8b3dc512f 130 PANTHER PTHR33204 1 126 7.1E-45 T 16-09-2016 Spa2297_RS10470 4613d904482b49cd3e612ea8b3dc512f 130 Pfam PF01638 HxlR-like helix-turn-helix 20 106 4.1E-32 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 SUPERFAMILY SSF46785 12 80 5.78E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 Gene3D G3DSA:1.10.10.10 6 83 4.4E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 Gene3D G3DSA:3.40.50.150 110 331 2.6E-41 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 SUPERFAMILY SSF53335 104 336 1.46E-39 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 Pfam PF00891 O-methyltransferase 131 325 2.1E-28 T 16-09-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 PANTHER PTHR11746 12 325 2.8E-31 T 16-09-2016 Spa2297_RS02655 4366031a4207f9b79ffa9685e7558db6 346 PANTHER PTHR11746:SF63 12 325 2.8E-31 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 Gene3D G3DSA:1.20.1610.10 448 615 2.1E-48 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 SUPERFAMILY SSF48208 270 741 4.42E-29 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 Gene3D G3DSA:3.30.2080.10 616 766 1.5E-44 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143:SF22 14 374 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143:SF22 456 761 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 Pfam PF07971 Glycosyl hydrolase family 92 243 754 3.5E-140 T 16-09-2016 IPR012939 Glycosyl hydrolase family 92 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143 14 374 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143 456 761 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 20 757 1.1E-167 T 16-09-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 Gene3D G3DSA:2.70.98.10 35 326 9.4E-96 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143 390 438 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 PANTHER PTHR12143:SF22 390 438 5.7E-132 T 16-09-2016 Spa2297_RS28860 698b1fbc27707dfec7b5f81437878706 772 Gene3D G3DSA:1.20.1050.60 350 440 1.1E-25 T 16-09-2016 Spa2297_RS29475 1f853ba1a085b5e5b7ae186b1f54ffc1 110 Pfam PF11338 Protein of unknown function (DUF3140) 13 102 3.8E-39 T 16-09-2016 IPR021487 Protein of unknown function DUF3140 Spa2297_RS29475 1f853ba1a085b5e5b7ae186b1f54ffc1 110 PANTHER PTHR40630 2 110 2.7E-40 T 16-09-2016 Spa2297_RS21635 16ab3fda6da2049d9b51bae30043935d 284 Pfam PF13369 Transglutaminase-like superfamily 50 200 1.5E-43 T 16-09-2016 IPR032698 Protein SirB1, N-terminal Spa2297_RS21635 16ab3fda6da2049d9b51bae30043935d 284 PANTHER PTHR31350:SF1 21 248 1.3E-35 T 16-09-2016 Spa2297_RS21635 16ab3fda6da2049d9b51bae30043935d 284 PANTHER PTHR31350 21 248 1.3E-35 T 16-09-2016 Spa2297_RS21635 16ab3fda6da2049d9b51bae30043935d 284 Pfam PF13371 Tetratricopeptide repeat 202 284 2.2E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 PANTHER PTHR30535:SF4 60 338 3.6E-105 T 16-09-2016 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 Gene3D G3DSA:3.40.50.1980 184 335 4.6E-16 T 16-09-2016 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 PANTHER PTHR30535 60 338 3.6E-105 T 16-09-2016 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 SUPERFAMILY SSF53807 65 336 1.22E-46 T 16-09-2016 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 Pfam PF01497 Periplasmic binding protein 83 310 3.4E-34 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS09490 7e9db7f7bbdbe9b452770f52b4597f48 342 Gene3D G3DSA:3.40.50.1980 80 183 2.6E-22 T 16-09-2016 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 Gene3D G3DSA:3.30.450.20 87 149 3.8E-6 T 16-09-2016 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 SUPERFAMILY SSF55781 234 348 5.89E-5 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 394 592 6.7E-42 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 Gene3D G3DSA:3.30.450.40 165 344 1.8E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 SUPERFAMILY SSF55874 628 710 1.36E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 SMART SM00331 367 592 1.4E-22 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 Gene3D G3DSA:3.30.565.10 613 699 2.5E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 PANTHER PTHR21021 344 601 7.7E-36 T 16-09-2016 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 PANTHER PTHR21021:SF19 344 601 7.7E-36 T 16-09-2016 Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 Pfam PF13581 Histidine kinase-like ATPase domain 606 715 2.9E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 SUPERFAMILY SSF55785 86 141 1.92E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS31520 f89e8b9d6aa1631a75b90216c3da5fa4 720 SUPERFAMILY SSF81606 384 591 1.62E-9 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24615 436eb5ed54ad57f19e7300e85d6dc604 233 SUPERFAMILY SSF53098 17 217 1.67E-55 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS24615 436eb5ed54ad57f19e7300e85d6dc604 233 Pfam PF01351 Ribonuclease HII 24 200 2.7E-33 T 16-09-2016 IPR024567 Ribonuclease HII/HIII domain Spa2297_RS24615 436eb5ed54ad57f19e7300e85d6dc604 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 36.072 T 16-09-2016 IPR022898 Ribonuclease HII GO:0004523 Spa2297_RS24615 436eb5ed54ad57f19e7300e85d6dc604 233 Gene3D G3DSA:3.30.420.10 22 162 4.8E-39 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS24615 436eb5ed54ad57f19e7300e85d6dc604 233 PANTHER PTHR10954 3 227 3.5E-53 T 16-09-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 SUPERFAMILY SSF142984 484 563 4.71E-18 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 SUPERFAMILY SSF140490 567 646 8.76E-22 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 PANTHER PTHR11780 108 190 3.2E-278 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 PANTHER PTHR11780 217 646 3.2E-278 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 52 158 1.2E-23 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 SMART SM00928 568 615 5.7E-16 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 Pfam PF10531 SLBB domain 486 514 5.0E-7 T 16-09-2016 IPR019554 Soluble ligand binding domain Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 291 461 3.5E-50 T 16-09-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 SUPERFAMILY SSF52833 45 159 4.03E-29 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 581 592 - T 16-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 PANTHER PTHR11780:SF10 108 190 3.2E-278 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 PANTHER PTHR11780:SF10 217 646 3.2E-278 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 Gene3D G3DSA:3.40.30.10 111 159 8.8E-4 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 SUPERFAMILY SSF142019 252 482 2.09E-84 T 16-09-2016 Spa2297_RS27310 9e9d6f6785d317720376dd1ecaeaf9c1 652 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 571 646 2.0E-21 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 882 917 3.4E-7 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 734 771 2.7E-7 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 924 958 6.7E-6 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 985 1019 1.4E-5 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 1198 1228 3.6E-9 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF05593 RHS Repeat 713 750 1.4E-6 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 PANTHER PTHR32305:SF6 1123 1413 1.2E-104 T 16-09-2016 Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 PANTHER PTHR32305:SF6 492 1050 1.2E-104 T 16-09-2016 Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 822 859 1.8E-4 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1198 1228 8.8E-9 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 734 774 1.9E-6 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 560 594 4.9E-5 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 881 921 3.2E-5 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 696 731 2.0E-5 T 16-09-2016 IPR006530 YD repeat Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 PANTHER PTHR32305 1123 1413 1.2E-104 T 16-09-2016 Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 PANTHER PTHR32305 492 1050 1.2E-104 T 16-09-2016 Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 Pfam PF03527 RHS protein 1300 1330 1.2E-7 T 16-09-2016 IPR001826 RHS protein Spa2297_RS12570 1ccc69cbcfca06a930c93a5d613d052c 1523 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1326 1399 9.3E-21 T 16-09-2016 IPR022385 Rhs repeat-associated core GO:0097264 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 2.1E-8 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 2.1E-8 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 Gene3D G3DSA:3.40.50.880 4 191 2.0E-66 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 SUPERFAMILY SSF52317 4 190 9.02E-56 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PANTHER PTHR11922:SF7 1 188 2.9E-81 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 2.3E-13 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 2.3E-13 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 2.3E-13 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PANTHER PTHR11922 1 188 2.9E-81 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 Pfam PF00117 Glutamine amidotransferase class-I 7 190 2.2E-52 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 122 134 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 167 180 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 49 58 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 5 19 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 102 110 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 PRINTS PR00097 Anthranilate synthase component II signature 77 88 4.7E-34 T 16-09-2016 Spa2297_RS16705 cd098eb1b610a0093cbf1fab8a2b0b40 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 188 2.6E-60 T 16-09-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 Gene3D G3DSA:3.40.80.10 45 240 6.8E-45 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 69 222 3.2E-11 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 SMART SM00701 45 194 8.1E-57 T 16-09-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 PANTHER PTHR11022 4 189 2.6E-50 T 16-09-2016 IPR015510 Peptidoglycan recognition protein GO:0008745|GO:0009253 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 PANTHER PTHR11022 209 234 2.6E-50 T 16-09-2016 IPR015510 Peptidoglycan recognition protein GO:0008745|GO:0009253 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 PANTHER PTHR11022:SF41 4 189 2.6E-50 T 16-09-2016 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 PANTHER PTHR11022:SF41 209 234 2.6E-50 T 16-09-2016 Spa2297_RS09040 8eee6b4bae664310dc4e16fb60fae63b 244 SUPERFAMILY SSF55846 45 236 1.31E-41 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 218 7.0E-27 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 Pfam PF00072 Response regulator receiver domain 4 114 3.7E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 PANTHER PTHR26402 2 218 1.5E-96 T 16-09-2016 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 PANTHER PTHR26402:SF556 2 218 1.5E-96 T 16-09-2016 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 Gene3D G3DSA:3.40.50.2300 2 120 1.4E-35 T 16-09-2016 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 SMART SM00862 147 218 3.4E-29 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 Gene3D G3DSA:1.10.10.10 126 218 2.2E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 SMART SM00448 2 113 1.2E-39 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08825 191d692d7ec4827f152ebab4958367c9 221 SUPERFAMILY SSF52172 2 176 3.32E-37 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS26970 0c82951bb5f1e1ccb46d4c434b8e7887 353 PANTHER PTHR11228:SF26 5 319 3.5E-88 T 16-09-2016 Spa2297_RS26970 0c82951bb5f1e1ccb46d4c434b8e7887 353 PANTHER PTHR11228 5 319 3.5E-88 T 16-09-2016 Spa2297_RS26970 0c82951bb5f1e1ccb46d4c434b8e7887 353 Gene3D G3DSA:3.80.30.20 63 288 5.6E-6 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS26970 0c82951bb5f1e1ccb46d4c434b8e7887 353 SUPERFAMILY SSF102114 63 293 1.86E-12 T 16-09-2016 Spa2297_RS26970 0c82951bb5f1e1ccb46d4c434b8e7887 353 Pfam PF04055 Radical SAM superfamily 64 236 1.4E-8 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 PANTHER PTHR20852:SF7 1 453 4.5E-171 T 16-09-2016 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 6.6E-126 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 1.1E-28 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 SUPERFAMILY SSF54368 8 103 1.96E-30 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 16-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 PANTHER PTHR20852 1 453 4.5E-171 T 16-09-2016 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 SUPERFAMILY SSF55931 106 450 1.37E-112 T 16-09-2016 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 Gene3D G3DSA:3.10.20.70 6 107 2.7E-39 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 SMART SM01230 104 363 6.3E-121 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09365 627a8c8cca7c626ade3539ed33f5507c 453 Gene3D G3DSA:3.30.590.10 108 441 5.8E-112 T 16-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 Pfam PF00005 ABC transporter 48 195 1.8E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 PANTHER PTHR24220:SF558 34 286 8.8E-99 T 16-09-2016 Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 SMART SM00382 57 243 2.1E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 SUPERFAMILY SSF52540 21 256 5.01E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 PANTHER PTHR24220 34 286 8.8E-99 T 16-09-2016 Spa2297_RS09500 9f6b8578de69af89f2ce5ddbc0dc2f93 286 Gene3D G3DSA:3.40.50.300 25 259 5.1E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04810 9e9d4cdc392c1509a67c855bfaed10f0 185 Pfam PF04073 Aminoacyl-tRNA editing domain 65 165 4.9E-15 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS04810 9e9d4cdc392c1509a67c855bfaed10f0 185 Gene3D G3DSA:3.90.960.10 36 179 1.1E-27 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS04810 9e9d4cdc392c1509a67c855bfaed10f0 185 PANTHER PTHR30411 2 180 3.3E-70 T 16-09-2016 Spa2297_RS04810 9e9d4cdc392c1509a67c855bfaed10f0 185 SUPERFAMILY SSF55826 36 179 7.06E-23 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS04810 9e9d4cdc392c1509a67c855bfaed10f0 185 PANTHER PTHR30411:SF1 2 180 3.3E-70 T 16-09-2016 Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 SUPERFAMILY SSF53613 2 294 6.39E-59 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 Gene3D G3DSA:3.40.1190.20 33 295 1.2E-69 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 PANTHER PTHR10584 2 294 1.6E-92 T 16-09-2016 Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.2E-97 T 16-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 Pfam PF00294 pfkB family carbohydrate kinase 20 285 2.8E-38 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.9E-98 T 16-09-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 PIRSF PIRSF000535 1 301 3.4E-67 T 16-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spa2297_RS13915 da364bd3ec960086a3efd135ce869a34 315 PANTHER PTHR10584:SF170 2 294 1.6E-92 T 16-09-2016 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 PANTHER PTHR11908 8 124 1.4E-38 T 16-09-2016 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 SUPERFAMILY SSF54292 12 97 4.46E-27 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 PANTHER PTHR11908:SF66 142 162 1.4E-38 T 16-09-2016 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 PANTHER PTHR11908 142 162 1.4E-38 T 16-09-2016 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 62 6.7E-9 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 Gene3D G3DSA:1.10.150.120 84 184 2.3E-32 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 SUPERFAMILY SSF47741 93 182 3.14E-28 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 Pfam PF01799 [2Fe-2S] binding domain 82 172 4.8E-29 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 Gene3D G3DSA:3.10.20.30 10 83 1.6E-31 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS03820 ef818368d3beadd5e9cd61923b4edf83 197 PANTHER PTHR11908:SF66 8 124 1.4E-38 T 16-09-2016 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 509 697 2.4E-50 T 16-09-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 Pfam PF07690 Major Facilitator Superfamily 298 475 6.7E-9 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 Gene3D G3DSA:3.40.50.300 509 709 1.1E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 Pfam PF02223 Thymidylate kinase 514 697 2.8E-46 T 16-09-2016 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 PANTHER PTHR10344 87 866 0.0 T 16-09-2016 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 PANTHER PTHR10344:SF0 87 866 0.0 T 16-09-2016 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 ProSitePatterns PS01331 Thymidylate kinase signature. 599 611 - T 16-09-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 Gene3D G3DSA:1.20.1250.20 290 476 4.0E-14 T 16-09-2016 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 Hamap MF_00165 Thymidylate kinase [tmk]. 510 709 31.014 T 16-09-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 SUPERFAMILY SSF52540 509 710 1.13E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18000 e69cefc3b58dff3c76b73fb0bc4440ab 1120 SUPERFAMILY SSF103473 287 470 4.58E-13 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 Gene3D G3DSA:1.10.10.10 159 218 3.8E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 SMART SM00448 2 115 7.4E-34 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 PANTHER PTHR26402:SF151 2 217 8.1E-95 T 16-09-2016 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 Gene3D G3DSA:3.40.50.2300 3 158 7.7E-41 T 16-09-2016 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 SUPERFAMILY SSF52172 3 132 5.83E-35 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 Pfam PF00072 Response regulator receiver domain 4 115 6.7E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 SUPERFAMILY SSF46894 139 219 1.05E-21 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 SMART SM00421 156 213 1.7E-24 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 PANTHER PTHR26402 2 217 8.1E-95 T 16-09-2016 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 1.3E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.1E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.1E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS15560 ac3294c96e1890dee93e56858c148a81 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.1E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 PANTHER PTHR11695 15 344 6.7E-129 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 PANTHER PTHR11695:SF261 15 344 6.7E-129 T 16-09-2016 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 Pfam PF00107 Zinc-binding dehydrogenase 185 306 1.6E-18 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 142 2.1E-26 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 SUPERFAMILY SSF51735 148 310 1.37E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 SMART SM00829 13 340 1.8E-6 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 Gene3D G3DSA:3.40.50.720 182 287 1.3E-21 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 SUPERFAMILY SSF50129 11 170 1.98E-46 T 16-09-2016 IPR011032 GroES-like Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 Gene3D G3DSA:3.90.180.10 3 181 9.0E-58 T 16-09-2016 IPR011032 GroES-like Spa2297_RS00370 c6c864ca96c0877ba121d4e2bc931052 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS21965 a4b9cb46edd800f039a345b6dc93f49d 373 Gene3D G3DSA:3.40.50.720 16 238 5.5E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21965 a4b9cb46edd800f039a345b6dc93f49d 373 PANTHER PTHR10366 27 327 3.0E-59 T 16-09-2016 Spa2297_RS21965 a4b9cb46edd800f039a345b6dc93f49d 373 SUPERFAMILY SSF51735 25 330 7.4E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21965 a4b9cb46edd800f039a345b6dc93f49d 373 PANTHER PTHR10366:SF124 27 327 3.0E-59 T 16-09-2016 Spa2297_RS21965 a4b9cb46edd800f039a345b6dc93f49d 373 Pfam PF01370 NAD dependent epimerase/dehydratase family 29 237 3.0E-16 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 Gene3D G3DSA:2.30.40.10 346 361 1.0E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 Gene3D G3DSA:2.30.40.10 5 52 1.0E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 PANTHER PTHR11113:SF7 1 380 4.7E-152 T 16-09-2016 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 SUPERFAMILY SSF51556 52 346 3.4E-91 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 Pfam PF01979 Amidohydrolase family 48 374 3.1E-28 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 Gene3D G3DSA:3.20.20.140 53 345 4.2E-101 T 16-09-2016 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 PIRSF PIRSF038994 9 378 2.3E-106 T 16-09-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 PANTHER PTHR11113 1 380 4.7E-152 T 16-09-2016 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 370 9.6E-79 T 16-09-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 SUPERFAMILY SSF51338 4 52 1.92E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14855 47a78cbc1c7d40d16cdc4d55b04c4165 381 SUPERFAMILY SSF51338 346 364 1.92E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 SUPERFAMILY SSF56112 15 323 2.13E-62 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 SMART SM00220 19 271 2.0E-46 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 47 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 PANTHER PTHR24362:SF160 3 361 4.1E-94 T 16-09-2016 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 Gene3D G3DSA:3.30.200.20 11 95 7.8E-17 T 16-09-2016 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 Gene3D G3DSA:1.10.510.10 102 329 2.6E-38 T 16-09-2016 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 PANTHER PTHR24362 3 361 4.1E-94 T 16-09-2016 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 Pfam PF00069 Protein kinase domain 20 263 2.2E-39 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS05935 354bd96e81691f58771beac5a75f355e 465 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS29780 29b197eebe90599ed824e2c5e9f65eb9 184 Pfam PF04892 VanZ like family 49 166 7.0E-22 T 16-09-2016 IPR006976 VanZ-like Spa2297_RS29780 29b197eebe90599ed824e2c5e9f65eb9 184 PANTHER PTHR36834:SF1 34 175 2.3E-36 T 16-09-2016 Spa2297_RS29780 29b197eebe90599ed824e2c5e9f65eb9 184 PANTHER PTHR36834 34 175 2.3E-36 T 16-09-2016 Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 Gene3D G3DSA:2.60.120.260 351 488 1.7E-11 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 SUPERFAMILY SSF49785 350 484 3.69E-8 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 PANTHER PTHR21712 7 122 2.0E-34 T 16-09-2016 Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 PANTHER PTHR21712 156 257 2.0E-34 T 16-09-2016 Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 PANTHER PTHR21712:SF4 7 122 2.0E-34 T 16-09-2016 Spa2297_RS15040 8ab67b163e8846afa11562c849f4090e 491 PANTHER PTHR21712:SF4 156 257 2.0E-34 T 16-09-2016 Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 Gene3D G3DSA:3.40.50.720 5 267 5.6E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 1.5E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.5E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.5E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 1.5E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 9.8E-19 T 16-09-2016 Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322:SF211 178 210 6.1E-74 T 16-09-2016 Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322:SF211 16 35 6.1E-74 T 16-09-2016 Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322 178 210 6.1E-74 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322 16 35 6.1E-74 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322 53 159 6.1E-74 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 PANTHER PTHR24322:SF211 53 159 6.1E-74 T 16-09-2016 Spa2297_RS30020 d68ebcaeae304bc8a721ab8210606a16 308 SUPERFAMILY SSF51735 8 262 3.41E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 SUPERFAMILY SSF48592 6 133 6.49E-76 T 16-09-2016 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 SUPERFAMILY SSF48592 404 518 6.49E-76 T 16-09-2016 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 Gene3D G3DSA:1.10.560.10 369 515 6.8E-40 T 16-09-2016 IPR027413 GroEL-like equatorial domain Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 16-09-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.7E-249 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 Gene3D G3DSA:3.50.7.10 195 368 3.9E-92 T 16-09-2016 IPR027409 GroEL-like apical domain Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 5.7E-98 T 16-09-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 SUPERFAMILY SSF54849 137 202 6.18E-27 T 16-09-2016 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 Gene3D G3DSA:1.10.560.10 6 194 1.8E-48 T 16-09-2016 IPR027413 GroEL-like equatorial domain Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 PANTHER PTHR11353 1 541 6.2E-223 T 16-09-2016 Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 SUPERFAMILY SSF52029 184 374 1.02E-81 T 16-09-2016 IPR027409 GroEL-like apical domain Spa2297_RS14805 7e1b6b3c679976070b80947a233e8b05 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.511 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 SUPERFAMILY SSF46689 14 88 3.08E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 Gene3D G3DSA:1.10.357.10 24 201 4.1E-32 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 PANTHER PTHR30055:SF74 9 204 1.8E-85 T 16-09-2016 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 9.9E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06725 127d2e0238df5836faa99f8f9f3071f3 205 PANTHER PTHR30055 9 204 1.8E-85 T 16-09-2016 Spa2297_RS20525 905db2aa03ecf80ef93e16e1d230f69d 160 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 41 143 4.8E-17 T 16-09-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 Spa2297_RS20525 905db2aa03ecf80ef93e16e1d230f69d 160 SUPERFAMILY SSF81343 35 157 1.35E-33 T 16-09-2016 Spa2297_RS20525 905db2aa03ecf80ef93e16e1d230f69d 160 Gene3D G3DSA:1.20.950.10 30 159 9.0E-39 T 16-09-2016 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 1.7E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 Gene3D G3DSA:1.10.357.10 16 175 3.1E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 PANTHER PTHR30055 2 165 1.2E-29 T 16-09-2016 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 SUPERFAMILY SSF46689 13 90 2.62E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.6E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.6E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26055 6ea8c31aad1ba602d3b42653bf3b22bd 192 PANTHER PTHR30055:SF18 2 165 1.2E-29 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115 329 728 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115 276 309 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.0E-6 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PRINTS PR00315 GTP-binding elongation factor signature 26 39 5.0E-6 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.0E-6 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SUPERFAMILY SSF50447 331 436 1.66E-22 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Gene3D G3DSA:2.40.30.10 330 440 1.1E-26 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115:SF98 7 195 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Pfam PF14492 Elongation Factor G, domain II 440 512 3.1E-24 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SUPERFAMILY SSF54980 440 517 1.08E-17 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115 7 195 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Gene3D G3DSA:3.30.70.870 441 512 1.8E-24 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115:SF98 276 309 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Pfam PF00679 Elongation factor G C-terminus 637 723 6.9E-22 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 153 2.8E-15 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SUPERFAMILY SSF52540 21 307 2.11E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Gene3D G3DSA:3.30.70.240 639 725 1.5E-21 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Gene3D G3DSA:3.30.230.10 520 638 1.4E-47 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Pfam PF00009 Elongation factor Tu GTP binding domain 23 170 1.2E-30 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Pfam PF03144 Elongation factor Tu domain 2 350 426 2.6E-9 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 PANTHER PTHR23115:SF98 329 728 2.8E-279 T 16-09-2016 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Pfam PF03764 Elongation factor G, domain IV 516 633 5.9E-40 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 Gene3D G3DSA:3.40.50.300 20 312 3.6E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SUPERFAMILY SSF54980 637 728 6.23E-21 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SMART SM00838 636 724 3.2E-20 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SMART SM00889 516 634 1.1E-58 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS05800 5ea52796d0e40151e40276494293a6e5 732 SUPERFAMILY SSF54211 516 633 1.77E-35 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS05005 eba5148c3f5835ba864ad851751eab59 216 PANTHER PTHR33169 63 187 3.0E-44 T 16-09-2016 Spa2297_RS05005 eba5148c3f5835ba864ad851751eab59 216 SUPERFAMILY SSF46785 67 165 4.26E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05005 eba5148c3f5835ba864ad851751eab59 216 Gene3D G3DSA:1.10.10.10 70 155 1.3E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05005 eba5148c3f5835ba864ad851751eab59 216 PANTHER PTHR33169:SF11 63 187 3.0E-44 T 16-09-2016 Spa2297_RS05005 eba5148c3f5835ba864ad851751eab59 216 Pfam PF03551 Transcriptional regulator PadR-like family 81 149 3.7E-21 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 16-09-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 Gene3D G3DSA:3.20.20.70 1 359 7.2E-123 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 PANTHER PTHR10683:SF12 1 364 3.7E-258 T 16-09-2016 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 SUPERFAMILY SSF51569 2 359 1.01E-75 T 16-09-2016 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 Hamap MF_00493 Transaldolase [tal]. 1 370 163.024 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 1.3E-132 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 PANTHER PTHR10683 1 364 3.7E-258 T 16-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 PIRSF PIRSF036915 1 372 1.1E-180 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS07805 1acda9179e7e78acb34b6c7315b5ae1b 372 Pfam PF00923 Transaldolase 15 359 1.5E-82 T 16-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 PANTHER PTHR21235 3 251 4.4E-121 T 16-09-2016 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 251 47.368 T 16-09-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 Gene3D G3DSA:3.20.20.70 6 251 1.2E-101 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 Pfam PF00977 Histidine biosynthesis protein 6 234 4.0E-87 T 16-09-2016 IPR006062 Histidine biosynthesis GO:0000105 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 SUPERFAMILY SSF51366 3 251 9.42E-83 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 PANTHER PTHR21235:SF2 3 251 4.4E-121 T 16-09-2016 Spa2297_RS08350 333ae1bae99a1b6a064c30a19505a0b3 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 251 3.2E-108 T 16-09-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 Pfam PF07730 Histidine kinase 262 327 1.2E-12 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 SUPERFAMILY SSF55874 337 448 1.07E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 Pfam PF13796 Putative sensor 46 234 7.6E-49 T 16-09-2016 IPR025828 Putative sensor domain Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 PANTHER PTHR24421:SF13 94 452 2.0E-221 T 16-09-2016 Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 PANTHER PTHR24421 94 452 2.0E-221 T 16-09-2016 Spa2297_RS19435 74db9126bfb788ab2966cf7d3bb7d428 455 Gene3D G3DSA:3.30.565.10 366 450 2.6E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15900 43a61e74e95b427d5d497fc9d6d209e1 206 Gene3D G3DSA:3.40.630.30 25 201 1.3E-41 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15900 43a61e74e95b427d5d497fc9d6d209e1 206 SMART SM01006 29 77 3.4E-11 T 16-09-2016 IPR019432 Siderophore biosynthesis protein, conserved domain Spa2297_RS15900 43a61e74e95b427d5d497fc9d6d209e1 206 Pfam PF13523 Acetyltransferase (GNAT) domain 32 176 2.0E-43 T 16-09-2016 Spa2297_RS15900 43a61e74e95b427d5d497fc9d6d209e1 206 SUPERFAMILY SSF55729 24 201 1.27E-33 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15900 43a61e74e95b427d5d497fc9d6d209e1 206 PANTHER PTHR31438 9 205 3.0E-48 T 16-09-2016 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Pfam PF01238 Phosphomannose isomerase type I 3 349 2.3E-68 T 16-09-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PANTHER PTHR10309 1 381 1.1E-123 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 121 129 - T 16-09-2016 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Gene3D G3DSA:2.60.120.10 234 269 4.8E-59 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Gene3D G3DSA:2.60.120.10 6 135 4.8E-59 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PIRSF PIRSF001480 1 383 6.4E-94 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Gene3D G3DSA:1.10.441.10 136 227 2.9E-21 T 16-09-2016 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Gene3D G3DSA:1.10.441.10 270 283 2.9E-21 T 16-09-2016 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 SUPERFAMILY SSF51182 2 374 8.57E-95 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PANTHER PTHR10309:SF0 1 381 1.1E-123 T 16-09-2016 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 2 377 8.8E-73 T 16-09-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 Gene3D G3DSA:2.60.120.10 284 380 1.9E-13 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 216 231 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 251 270 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 232 251 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 76 97 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 270 289 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 121 144 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS13095 32c4d603f700bb7a37802400aaba34c3 383 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 5.2E-63 T 16-09-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 SUPERFAMILY SSF48264 18 417 4.19E-53 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 PANTHER PTHR11712 20 417 3.2E-57 T 16-09-2016 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 PRINTS PR00359 B-class P450 signature 307 334 2.5E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 PRINTS PR00359 B-class P450 signature 156 172 2.5E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 PRINTS PR00359 B-class P450 signature 211 233 2.5E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 Gene3D G3DSA:1.10.630.10 18 417 7.9E-78 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30720 9cd427476883f9b8812afab1b95548eb 420 PANTHER PTHR11712:SF234 20 417 3.2E-57 T 16-09-2016 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 PANTHER PTHR10909 1 379 7.6E-114 T 16-09-2016 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 SUPERFAMILY SSF56645 6 235 3.14E-57 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 PANTHER PTHR10909:SF121 1 379 7.6E-114 T 16-09-2016 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Gene3D G3DSA:1.10.540.10 7 109 4.4E-23 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Gene3D G3DSA:1.20.140.10 213 378 4.1E-48 T 16-09-2016 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 113 196 2.1E-17 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 366 3.9E-31 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 SUPERFAMILY SSF47203 220 377 1.93E-39 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Gene3D G3DSA:2.40.110.10 113 212 3.5E-26 T 16-09-2016 Spa2297_RS14495 eefe8b0138cf4e7c884a8d593a9a9921 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 108 5.6E-23 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 266 34.656 T 16-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 Gene3D G3DSA:3.20.20.70 9 268 1.0E-93 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 Pfam PF00290 Tryptophan synthase alpha chain 13 249 1.7E-77 T 16-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 16-09-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 SUPERFAMILY SSF51366 8 249 1.49E-78 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 262 3.8E-68 T 16-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 PANTHER PTHR10314 78 133 1.2E-13 T 16-09-2016 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 PANTHER PTHR10314 4 55 1.2E-13 T 16-09-2016 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 PANTHER PTHR10314:SF4 78 133 1.2E-13 T 16-09-2016 Spa2297_RS08295 b9cb632404e07bea34410f2eada0cc90 271 PANTHER PTHR10314:SF4 4 55 1.2E-13 T 16-09-2016 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 PANTHER PTHR30173 76 262 1.1E-58 T 16-09-2016 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 PANTHER PTHR30173:SF13 76 262 1.1E-58 T 16-09-2016 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 Gene3D G3DSA:1.10.10.10 198 260 6.3E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 90 259 6.1E-79 T 16-09-2016 IPR014298 RNA polymerase sigma-X type Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 SUPERFAMILY SSF88659 189 259 1.87E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 Pfam PF04542 Sigma-70 region 2 105 172 1.2E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 100 257 1.4E-29 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 Gene3D G3DSA:1.10.1740.10 89 197 6.2E-29 T 16-09-2016 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 SUPERFAMILY SSF88946 83 191 6.87E-27 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18565 52a816e6ca1dc556412158de1f209f83 264 Pfam PF08281 Sigma-70, region 4 204 255 8.0E-14 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22055 d06f641c0fcbdf6adcfbe14d92a7fb59 212 Gene3D G3DSA:3.40.50.1820 25 191 1.7E-14 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS22055 d06f641c0fcbdf6adcfbe14d92a7fb59 212 PANTHER PTHR13136:SF4 93 209 4.3E-36 T 16-09-2016 Spa2297_RS22055 d06f641c0fcbdf6adcfbe14d92a7fb59 212 PANTHER PTHR13136 93 209 4.3E-36 T 16-09-2016 IPR026555 KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein Spa2297_RS22055 d06f641c0fcbdf6adcfbe14d92a7fb59 212 SUPERFAMILY SSF53474 9 195 4.1E-14 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 SMART SM01130 6 291 1.6E-87 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PANTHER PTHR12128 6 290 7.2E-81 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PANTHER PTHR12128:SF15 6 290 7.2E-81 T 16-09-2016 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.8E-8 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.8E-8 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 1.8E-8 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 SUPERFAMILY SSF51569 4 289 6.07E-75 T 16-09-2016 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 Gene3D G3DSA:3.20.20.70 3 290 1.8E-82 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 Pfam PF00701 Dihydrodipicolinate synthetase family 8 286 9.2E-45 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS27780 50ef29002b474c2823e8d94b2b6693a5 296 PIRSF PIRSF001365 3 294 4.3E-68 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 Gene3D G3DSA:3.40.50.300 35 145 7.3E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 Gene3D G3DSA:1.10.10.10 538 589 2.1E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 SUPERFAMILY SSF46894 534 591 5.1E-15 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 SMART SM00421 537 594 2.1E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 SUPERFAMILY SSF52540 20 210 3.53E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 Pfam PF00196 Bacterial regulatory proteins, luxR family 540 587 5.2E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 554 570 6.9E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 570 582 6.9E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS28580 69704a4449971c315d58456dde87b1a2 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 540 554 6.9E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS10160 19726cfff4ac6e90c5478724f6a98df5 168 PANTHER PTHR37042 1 165 6.2E-41 T 16-09-2016 Spa2297_RS10160 19726cfff4ac6e90c5478724f6a98df5 168 PANTHER PTHR37042:SF2 1 165 6.2E-41 T 16-09-2016 Spa2297_RS10160 19726cfff4ac6e90c5478724f6a98df5 168 Pfam PF13577 SnoaL-like domain 64 165 2.6E-6 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS10160 19726cfff4ac6e90c5478724f6a98df5 168 Gene3D G3DSA:3.10.450.50 57 166 1.3E-4 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS10160 19726cfff4ac6e90c5478724f6a98df5 168 SUPERFAMILY SSF54427 64 164 5.18E-5 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 7.5E-48 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PANTHER PTHR22773:SF50 1 477 2.5E-190 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PANTHER PTHR22773 1 477 2.5E-190 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PANTHER PTHR22773 512 612 2.5E-190 T 16-09-2016 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 7 656 9.5E-138 T 16-09-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 119 2.0E-10 T 16-09-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 Pfam PF00361 Proton-conducting membrane transporter 132 403 1.0E-75 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 1.9E-6 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 1.9E-6 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 1.9E-6 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19480 f16e929349ab9c61debfbcc0a3883400 664 PANTHER PTHR22773:SF50 512 612 2.5E-190 T 16-09-2016 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 PANTHER PTHR30385 7 163 4.1E-26 T 16-09-2016 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 158 1.2E-58 T 16-09-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 157 5.6E-25 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 Pfam PF04542 Sigma-70 region 2 14 76 2.4E-8 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 Gene3D G3DSA:1.10.10.10 95 157 5.0E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 Pfam PF08281 Sigma-70, region 4 102 153 2.3E-16 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 32 63 - T 16-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 PANTHER PTHR30385:SF1 7 163 4.1E-26 T 16-09-2016 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 SUPERFAMILY SSF88659 94 157 5.42E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 Gene3D G3DSA:1.10.1740.10 6 77 8.5E-14 T 16-09-2016 Spa2297_RS18390 6820ed61189ee87cdca39f9a434f3ec0 177 SUPERFAMILY SSF88946 6 88 2.35E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Pfam PF00704 Glycosyl hydrolases family 18 242 592 7.8E-74 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Gene3D G3DSA:3.10.50.10 506 564 1.5E-24 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SUPERFAMILY SSF54556 504 563 4.43E-15 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SUPERFAMILY SSF51445 562 605 8.24E-81 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SUPERFAMILY SSF51445 236 502 8.24E-81 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SMART SM00060 142 216 4.2E-11 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 PANTHER PTHR11177 237 293 3.6E-87 T 16-09-2016 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 PANTHER PTHR11177 316 606 3.6E-87 T 16-09-2016 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Gene3D G3DSA:2.60.40.10 141 224 4.1E-22 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 ProSitePatterns PS01095 Chitinases family 18 active site. 373 381 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Pfam PF00041 Fibronectin type III domain 143 218 2.9E-8 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SUPERFAMILY SSF49384 30 132 1.67E-30 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 99 112 - T 16-09-2016 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Gene3D G3DSA:3.20.20.80 234 505 3.8E-86 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Gene3D G3DSA:3.20.20.80 569 606 3.8E-86 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SMART SM00637 34 131 7.7E-42 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SMART SM00636 239 592 6.2E-117 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Pfam PF00553 Cellulose binding domain 34 131 2.1E-32 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 SUPERFAMILY SSF49265 141 225 7.3E-17 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS22715 1a5c515faf316d1c7ef189b9df40e479 607 Gene3D G3DSA:2.60.40.290 34 133 3.5E-35 T 16-09-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 168 1.8E-25 T 16-09-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 PANTHER PTHR21708:SF29 1 121 3.1E-171 T 16-09-2016 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 SUPERFAMILY SSF51735 1 157 3.66E-13 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 PANTHER PTHR21708:SF29 137 318 3.1E-171 T 16-09-2016 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 PANTHER PTHR21708 1 121 3.1E-171 T 16-09-2016 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 Gene3D G3DSA:3.40.50.720 1 194 2.4E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 PANTHER PTHR21708 137 318 3.1E-171 T 16-09-2016 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 SUPERFAMILY SSF48179 196 313 3.23E-27 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 Gene3D G3DSA:1.10.1040.10 197 313 3.6E-26 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS27320 bfebc27ec64df8ab15bb75dd58c4f3c0 323 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 314 9.9E-27 T 16-09-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 PANTHER PTHR26402 4 226 3.4E-87 T 16-09-2016 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 Pfam PF00072 Response regulator receiver domain 7 115 5.0E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 6.5E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 PANTHER PTHR26402:SF316 4 226 3.4E-87 T 16-09-2016 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 SUPERFAMILY SSF52172 2 171 2.78E-38 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 SMART SM00862 150 224 2.5E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 SMART SM00448 4 115 7.7E-39 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 Gene3D G3DSA:3.40.50.2300 3 122 1.4E-37 T 16-09-2016 Spa2297_RS25515 7604e3a6d2e5d0765386f4d15619758d 229 Gene3D G3DSA:1.10.10.10 128 226 7.0E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 6.6E-37 T 16-09-2016 IPR013264 DNA primase, catalytic core, N-terminal Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Gene3D G3DSA:3.90.580.10 3 102 4.7E-37 T 16-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 SMART SM00766 488 621 2.6E-28 T 16-09-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Gene3D G3DSA:3.40.1360.10 244 370 1.5E-40 T 16-09-2016 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 TIGRFAM TIGR01391 dnaG: DNA primase 5 421 3.3E-117 T 16-09-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Pfam PF01807 CHC2 zinc finger 6 101 9.5E-33 T 16-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Pfam PF13662 Toprim domain 263 333 4.8E-16 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Gene3D G3DSA:1.20.50.20 373 430 1.4E-9 T 16-09-2016 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Pfam PF08278 DNA primase DnaG DnaB-binding 489 609 1.4E-12 T 16-09-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 PIRSF PIRSF002811 2 632 4.3E-177 T 16-09-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 SMART SM00400 37 91 9.5E-35 T 16-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 PANTHER PTHR30313 3 633 2.2E-145 T 16-09-2016 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Hamap MF_00974 DNA primase [dnaG]. 4 626 26.951 T 16-09-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 SMART SM00493 262 338 3.5E-16 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 SUPERFAMILY SSF56731 117 429 1.41E-93 T 16-09-2016 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Gene3D G3DSA:3.90.980.10 117 243 3.1E-38 T 16-09-2016 IPR013264 DNA primase, catalytic core, N-terminal Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 Pfam PF10410 DnaB-helicase binding domain of primase 374 427 4.0E-15 T 16-09-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 Spa2297_RS10415 4c88712994566218da89e9272df8d493 642 SUPERFAMILY SSF57783 4 102 7.14E-33 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 Pfam PF03176 MMPL family 418 718 1.1E-35 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 Pfam PF03176 MMPL family 77 381 1.9E-48 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 PANTHER PTHR33406:SF2 4 744 1.1E-175 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 SUPERFAMILY SSF82866 121 348 3.01E-28 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 Gene3D G3DSA:1.20.1640.10 494 720 2.5E-34 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 Gene3D G3DSA:1.20.1640.10 143 349 1.0E-26 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 PANTHER PTHR33406 4 744 1.1E-175 T 16-09-2016 Spa2297_RS25730 e5ae77dc3052420b3f7f2a08eb527410 755 SUPERFAMILY SSF82866 469 714 7.19E-32 T 16-09-2016 Spa2297_RS07065 c802dbe788e4f9e2f1e2228f5b17764a 348 Pfam PF01032 FecCD transport family 35 342 1.7E-89 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS07065 c802dbe788e4f9e2f1e2228f5b17764a 348 Gene3D G3DSA:1.10.3470.10 20 344 2.7E-98 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS07065 c802dbe788e4f9e2f1e2228f5b17764a 348 SUPERFAMILY SSF81345 21 343 2.75E-80 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS07065 c802dbe788e4f9e2f1e2228f5b17764a 348 PANTHER PTHR30472:SF31 1 348 4.6E-185 T 16-09-2016 Spa2297_RS07065 c802dbe788e4f9e2f1e2228f5b17764a 348 PANTHER PTHR30472 1 348 4.6E-185 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 PIRSF PIRSF005902 17 312 2.7E-66 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 SUPERFAMILY SSF51556 132 311 1.12E-70 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 SUPERFAMILY SSF51556 30 100 1.12E-70 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 Gene3D G3DSA:3.20.20.140 25 98 2.5E-77 T 16-09-2016 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 Gene3D G3DSA:3.20.20.140 130 311 2.5E-77 T 16-09-2016 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 PANTHER PTHR10060:SF20 23 103 2.3E-111 T 16-09-2016 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 PANTHER PTHR10060:SF20 131 312 2.3E-111 T 16-09-2016 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 PANTHER PTHR10060 23 103 2.3E-111 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 PANTHER PTHR10060 131 312 2.3E-111 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS13705 23e06019f0dbcb603dfd92fea6405822 312 Pfam PF01026 TatD related DNase 33 310 5.0E-68 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 SUPERFAMILY SSF46785 9 66 3.64E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 Gene3D G3DSA:3.30.420.40 223 367 1.5E-40 T 16-09-2016 Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 Gene3D G3DSA:1.10.10.10 11 64 6.9E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 Pfam PF00480 ROK family 77 381 1.9E-52 T 16-09-2016 IPR000600 ROK family Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 PANTHER PTHR18964:SF108 51 386 1.7E-99 T 16-09-2016 Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 Gene3D G3DSA:3.30.420.40 70 222 3.5E-47 T 16-09-2016 Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 ProSitePatterns PS01125 ROK family signature. 219 246 - T 16-09-2016 IPR000600 ROK family Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 SUPERFAMILY SSF53067 75 384 3.29E-56 T 16-09-2016 Spa2297_RS01320 f81aea11d97949f664fce8ed6770a080 399 PANTHER PTHR18964 51 386 1.7E-99 T 16-09-2016 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 SUPERFAMILY SSF69336 1213 1478 7.98E-86 T 16-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Pfam PF00310 Glutamine amidotransferases class-II 11 419 2.4E-181 T 16-09-2016 IPR017932 Glutamine amidotransferase type 2 domain Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Gene3D G3DSA:3.20.20.70 429 788 4.9E-104 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 PANTHER PTHR11938:SF1 1 1483 0.0 T 16-09-2016 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Pfam PF01645 Conserved region in glutamate synthase 801 1164 9.2E-157 T 16-09-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 SUPERFAMILY SSF51395 434 1200 7.33E-262 T 16-09-2016 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Gene3D G3DSA:2.160.20.60 1218 1493 1.2E-101 T 16-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Gene3D G3DSA:3.20.20.70 817 1196 2.5E-180 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Gene3D G3DSA:3.60.20.10 11 428 5.0E-187 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 PANTHER PTHR11938 1 1483 0.0 T 16-09-2016 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Pfam PF01493 GXGXG motif 1249 1426 3.7E-74 T 16-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 SUPERFAMILY SSF56235 11 421 7.02E-148 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS08245 b740c08cfc0fab9fe92c897ba4b45ca5 1505 Pfam PF04898 Glutamate synthase central domain 446 736 5.5E-112 T 16-09-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 Gene3D G3DSA:1.20.1250.20 249 406 5.5E-19 T 16-09-2016 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 Gene3D G3DSA:1.20.1250.20 469 492 5.5E-19 T 16-09-2016 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 PANTHER PTHR23501:SF76 1 507 1.9E-202 T 16-09-2016 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 Pfam PF07690 Major Facilitator Superfamily 2 395 9.1E-46 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 Gene3D G3DSA:1.20.1250.20 1 185 4.5E-32 T 16-09-2016 Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 SUPERFAMILY SSF103473 1 183 7.32E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 SUPERFAMILY SSF103473 468 491 7.32E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 SUPERFAMILY SSF103473 234 405 7.32E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14200 ba3edc5dabdf9c465f3529fded2ee8ca 519 PANTHER PTHR23501 1 507 1.9E-202 T 16-09-2016 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 PANTHER PTHR22939 181 307 2.3E-49 T 16-09-2016 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 Gene3D G3DSA:2.30.42.10 122 240 6.6E-25 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 PANTHER PTHR22939 323 416 2.3E-49 T 16-09-2016 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 PANTHER PTHR22939:SF78 323 416 2.3E-49 T 16-09-2016 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 PANTHER PTHR22939:SF78 181 307 2.3E-49 T 16-09-2016 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 Pfam PF13180 PDZ domain 179 239 5.1E-11 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 SUPERFAMILY SSF50156 128 239 3.81E-19 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 SMART SM00228 149 231 3.3E-7 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS24110 5498aedeaa08a465bf52b39bb4187c86 434 Pfam PF02163 Peptidase family M50 13 387 1.1E-45 T 16-09-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Gene3D G3DSA:2.40.50.100 241 284 7.3E-8 T 16-09-2016 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Gene3D G3DSA:2.40.50.100 362 376 7.3E-8 T 16-09-2016 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Gene3D G3DSA:3.40.50.300 4 236 2.6E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 SUPERFAMILY SSF50331 238 376 7.65E-20 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 PANTHER PTHR24220 5 291 8.4E-165 T 16-09-2016 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Pfam PF00005 ABC transporter 22 163 3.3E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 SUPERFAMILY SSF52540 5 245 1.89E-83 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 PANTHER PTHR24220:SF151 5 291 8.4E-165 T 16-09-2016 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 SMART SM00382 30 213 1.5E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Gene3D G3DSA:2.40.50.140 285 359 1.8E-7 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS15050 2fe63274d078c381550bf1784e02728e 378 Pfam PF03459 TOBE domain 306 367 3.3E-7 T 16-09-2016 IPR005116 Transport-associated OB, type 1 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 SUPERFAMILY SSF46689 10 73 3.08E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 PANTHER PTHR30055 3 107 6.5E-32 T 16-09-2016 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 89 228 1.5E-6 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 Gene3D G3DSA:1.10.10.60 3 72 3.8E-26 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 PANTHER PTHR30055:SF90 3 107 6.5E-32 T 16-09-2016 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 SUPERFAMILY SSF48498 86 231 1.22E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.5E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02550 87b41ef4d4434ac5bd6f3c1ce5f119c0 242 Gene3D G3DSA:1.10.357.10 77 231 5.2E-59 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 TIGRFAM TIGR00593 pola: DNA polymerase I 19 905 5.7E-294 T 16-09-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SUPERFAMILY SSF47807 187 295 7.03E-27 T 16-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PANTHER PTHR10133 11 905 0.0 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SMART SM00482 663 870 7.5E-117 T 16-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 18 186 8.0E-54 T 16-09-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:1.10.150.20 202 261 4.4E-25 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Pfam PF00476 DNA polymerase family A 529 903 2.9E-140 T 16-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 823 839 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 655 670 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 701 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 769 780 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 632 654 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 802 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 721 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 732 757 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PRINTS PR00868 DNA-polymerase family A (pol I) signature 853 866 1.3E-75 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SUPERFAMILY SSF53098 328 497 4.55E-30 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SUPERFAMILY SSF56672 503 904 7.56E-138 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 PANTHER PTHR10133:SF27 11 905 0.0 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:1.20.1060.10 521 640 6.4E-32 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SMART SM00475 15 277 1.0E-146 T 16-09-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SUPERFAMILY SSF88723 13 186 2.04E-53 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:3.30.70.370 797 905 5.1E-65 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:3.30.70.370 641 689 5.1E-65 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 188 280 1.7E-26 T 16-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:1.10.150.20 690 796 1.9E-30 T 16-09-2016 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:3.30.420.10 329 520 1.7E-50 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SMART SM00474 325 496 6.3E-7 T 16-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 Gene3D G3DSA:3.40.50.1010 18 201 5.3E-67 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS08135 f36242f5e0676c7883c90d297f3c8fc9 907 SMART SM00279 189 224 3.7E-14 T 16-09-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 SUPERFAMILY SSF64288 72 251 3.45E-54 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 Gene3D G3DSA:3.40.1410.10 82 251 1.0E-55 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 SMART SM00345 27 84 7.8E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 PANTHER PTHR11751 137 156 1.5E-23 T 16-09-2016 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 PANTHER PTHR11751 40 91 1.5E-23 T 16-09-2016 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 Pfam PF07702 UTRA domain 104 244 1.7E-41 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 84 1.6E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 SMART SM00866 104 244 9.5E-42 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 SUPERFAMILY SSF46785 19 88 1.39E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.6E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.6E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS22135 5358e115752d50489642fc1d39dcca2d 254 Gene3D G3DSA:1.10.10.10 19 81 1.0E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 Gene3D G3DSA:3.30.450.40 14 195 1.9E-34 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 245 427 1.6E-42 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 SMART SM00065 22 198 5.8E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 Pfam PF01590 GAF domain 68 186 1.1E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 SUPERFAMILY SSF55874 459 550 4.45E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 SUPERFAMILY SSF81606 234 386 5.75E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 Pfam PF13581 Histidine kinase-like ATPase domain 464 549 1.4E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 SUPERFAMILY SSF55781 85 199 1.0E-15 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 PANTHER PTHR21021 142 436 6.8E-56 T 16-09-2016 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 SMART SM00331 219 427 7.3E-50 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28655 a3189660629aa6b857987374fed7b496 566 PANTHER PTHR21021:SF19 142 436 6.8E-56 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 SMART SM00354 7 79 1.3E-21 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 PANTHER PTHR30146:SF47 7 335 3.1E-189 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 Gene3D G3DSA:3.40.50.2300 62 179 3.2E-25 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 SUPERFAMILY SSF47413 7 67 3.73E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 Gene3D G3DSA:1.10.260.40 8 61 1.1E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 Gene3D G3DSA:3.40.50.2300 180 314 3.7E-34 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 Pfam PF13377 Periplasmic binding protein-like domain 174 332 4.7E-32 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 PANTHER PTHR30146 7 335 3.1E-189 T 16-09-2016 Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 SUPERFAMILY SSF53822 66 318 9.97E-46 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS06365 3b614f0d49b974520bb71b0634b22d0c 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 7.7E-14 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 SMART SM00922 146 240 1.8E-23 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 PANTHER PTHR13794:SF56 1 369 1.1E-185 T 16-09-2016 Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 119 2.7E-17 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 PANTHER PTHR13794 1 369 1.1E-185 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 Pfam PF13378 Enolase C-terminal domain-like 151 358 1.6E-49 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 Gene3D G3DSA:3.30.390.10 1 121 2.8E-42 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 SUPERFAMILY SSF54826 1 119 1.77E-30 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 SUPERFAMILY SSF51604 119 363 1.31E-59 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS00990 070b6cc49faf379fa1ec9f1d371de6ab 375 Gene3D G3DSA:3.20.20.120 122 352 2.9E-68 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS33525 f7c267028d47c4499b69f7013e300e4d 232 PANTHER PTHR10357 6 232 7.4E-123 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS33525 f7c267028d47c4499b69f7013e300e4d 232 SUPERFAMILY SSF51445 15 230 8.84E-76 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS33525 f7c267028d47c4499b69f7013e300e4d 232 Gene3D G3DSA:3.20.20.80 21 231 2.1E-65 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS33525 f7c267028d47c4499b69f7013e300e4d 232 PANTHER PTHR10357:SF74 6 232 7.4E-123 T 16-09-2016 Spa2297_RS33525 f7c267028d47c4499b69f7013e300e4d 232 Pfam PF00128 Alpha amylase, catalytic domain 71 230 1.4E-10 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 SUPERFAMILY SSF56176 17 194 5.14E-46 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 Pfam PF01565 FAD binding domain 29 164 2.3E-32 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 Pfam PF04030 D-arabinono-1,4-lactone oxidase 188 442 1.9E-80 T 16-09-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 Gene3D G3DSA:3.30.465.10 87 194 1.5E-30 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 PANTHER PTHR13878 17 444 2.0E-118 T 16-09-2016 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 29 62 - T 16-09-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 18 444 3.3E-119 T 16-09-2016 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 PIRSF PIRSF000136 9 445 4.6E-117 T 16-09-2016 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 Gene3D G3DSA:3.30.43.10 14 86 3.2E-23 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS24810 bbe5a90ae938a791fcf1e90b32349e54 445 PANTHER PTHR13878:SF5 17 444 2.0E-118 T 16-09-2016 Spa2297_RS20050 030722b208b786d27ce1fd7bb4703d07 317 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 236 2.5E-59 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS20050 030722b208b786d27ce1fd7bb4703d07 317 PANTHER PTHR33392:SF7 1 317 1.8E-114 T 16-09-2016 Spa2297_RS20050 030722b208b786d27ce1fd7bb4703d07 317 PANTHER PTHR33392 1 317 1.8E-114 T 16-09-2016 Spa2297_RS20050 030722b208b786d27ce1fd7bb4703d07 317 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 80 236 9.5E-47 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Pfam PF00271 Helicase conserved C-terminal domain 553 628 1.1E-19 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 706 3.0E-199 T 16-09-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SUPERFAMILY SSF52540 545 640 1.03E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SUPERFAMILY SSF52540 408 513 1.03E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031 547 642 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031 147 195 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Gene3D G3DSA:3.40.50.300 263 472 8.1E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Pfam PF01336 OB-fold nucleic acid binding domain 61 144 8.4E-10 T 16-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031:SF249 547 642 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031:SF249 147 195 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031:SF249 221 291 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031:SF249 666 716 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SMART SM00487 274 476 1.2E-31 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Gene3D G3DSA:3.40.50.300 473 677 1.7E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Pfam PF00270 DEAD/DEAH box helicase 300 452 2.9E-16 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031:SF249 308 519 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SUPERFAMILY SSF50249 14 189 6.51E-31 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031 221 291 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031 308 519 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 PANTHER PTHR24031 666 716 3.3E-97 T 16-09-2016 Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 Gene3D G3DSA:2.40.50.140 47 148 4.9E-14 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SMART SM00490 544 629 4.8E-23 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS23615 03e2e846a8d096cde42c7a9475d5fa79 741 SUPERFAMILY SSF52540 195 469 1.8E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF00072 Response regulator receiver domain 1704 1815 1.6E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF55874 1417 1610 5.24E-45 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF52172 1701 1821 2.28E-37 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00065 1130 1285 3.1E-5 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 338 469 1.1E-8 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Gene3D G3DSA:1.10.287.130 1351 1413 4.2E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF00672 HAMP domain 316 366 3.4E-7 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF00672 HAMP domain 867 917 3.8E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 706 877 8.37E-15 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1568 1586 5.4E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1533 1547 5.4E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1551 1561 5.4E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1592 1605 5.4E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00388 1360 1428 1.9E-23 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 890 981 7.32E-6 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Gene3D G3DSA:3.30.565.10 1414 1609 3.0E-44 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF13185 GAF domain 1129 1273 6.2E-17 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF55781 1094 1275 1.96E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 246 377 5.36E-10 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00448 1702 1816 3.4E-38 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Gene3D G3DSA:3.40.50.2300 1702 1822 3.1E-40 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 594 646 3.0E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 1054 1106 2.0E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 778 830 7.0E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 962 1014 1.5E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 410 462 3.5E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 124 186 0.0012 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 870 922 1.1E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 226 278 1.6E-5 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 502 554 1.2E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 686 738 1.3E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 35 84 5.2 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00304 318 370 4.1E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 522 688 2.44E-13 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SMART SM00387 1475 1608 7.3E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1475 1607 2.0E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF58104 982 1104 4.18E-9 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1361 1428 4.5E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 1523 1684 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 27 32 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 1701 1821 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 1358 1507 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 1304 1322 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 PANTHER PTHR24423 496 532 2.0E-142 T 16-09-2016 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 SUPERFAMILY SSF47384 1346 1430 5.69E-21 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24310 7c80b306d27d8bf4a85a06b7ccf05eb7 1823 Gene3D G3DSA:3.30.450.40 1115 1275 5.2E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 Gene3D G3DSA:3.20.20.140 72 395 3.1E-133 T 16-09-2016 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 Pfam PF01979 Amidohydrolase family 54 426 8.9E-32 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 SUPERFAMILY SSF51338 5 57 2.78E-23 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 SUPERFAMILY SSF51338 374 437 2.78E-23 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 SUPERFAMILY SSF51556 58 374 2.56E-102 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 PANTHER PTHR11647:SF4 1 444 6.1E-222 T 16-09-2016 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 PANTHER PTHR11647 1 444 6.1E-222 T 16-09-2016 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 TIGRFAM TIGR03178 allantoinase: allantoinase 5 443 7.2E-197 T 16-09-2016 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698|UniPathway: UPA00395 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 Hamap MF_01645 Allantoinase [allB]. 3 444 48.43 T 16-09-2016 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698|UniPathway: UPA00395 Spa2297_RS26435 b1e73ec8dc3e8f2b7a0474c21ad239ce 445 Gene3D G3DSA:2.30.40.10 6 71 1.0E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 Gene3D G3DSA:3.40.50.360 1 171 1.3E-36 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 PANTHER PTHR30543 1 185 2.2E-84 T 16-09-2016 Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 3 196 3.6E-77 T 16-09-2016 IPR023932 Uncharacterised protein family, CE1759 Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 PANTHER PTHR30543:SF8 1 185 2.2E-84 T 16-09-2016 Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 SUPERFAMILY SSF52218 1 175 5.87E-32 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS18685 0160cd92144ad01b4784b9a08cc35601 203 Pfam PF03358 NADPH-dependent FMN reductase 1 151 1.3E-37 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 SUPERFAMILY SSF52980 925 1065 4.99E-5 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Pfam PF13361 UvrD-like helicase C-terminal domain 660 790 7.3E-20 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070 454 575 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Pfam PF12705 PD-(D/E)XK nuclease superfamily 895 1151 2.5E-37 T 16-09-2016 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070:SF4 681 748 0.0 T 16-09-2016 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070:SF4 1 423 0.0 T 16-09-2016 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070 681 748 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070 1 423 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 272 1.1E-47 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 SUPERFAMILY SSF52540 2 421 2.78E-98 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 SUPERFAMILY SSF52540 597 806 2.78E-98 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070:SF4 454 575 0.0 T 16-09-2016 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070:SF4 765 1113 0.0 T 16-09-2016 Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Gene3D G3DSA:3.40.50.300 1 136 1.1E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Gene3D G3DSA:3.40.50.300 177 276 1.1E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Gene3D G3DSA:3.40.50.300 289 410 2.4E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 Gene3D G3DSA:3.40.50.300 708 809 2.4E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21885 287010076ab3a352fe9b4f19133190d4 1162 PANTHER PTHR11070 765 1113 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS27635 012cbdb2b1436fc6198722a953c61d40 404 SUPERFAMILY SSF53756 46 396 2.56E-54 T 16-09-2016 Spa2297_RS27635 012cbdb2b1436fc6198722a953c61d40 404 Gene3D G3DSA:3.40.50.2000 210 373 1.7E-24 T 16-09-2016 Spa2297_RS27635 012cbdb2b1436fc6198722a953c61d40 404 PANTHER PTHR12526 158 400 1.1E-67 T 16-09-2016 Spa2297_RS27635 012cbdb2b1436fc6198722a953c61d40 404 PANTHER PTHR12526:SF353 158 400 1.1E-67 T 16-09-2016 Spa2297_RS27635 012cbdb2b1436fc6198722a953c61d40 404 Pfam PF00534 Glycosyl transferases group 1 216 374 1.1E-27 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 PANTHER PTHR11695:SF269 19 365 3.4E-122 T 16-09-2016 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 Gene3D G3DSA:3.90.180.10 5 187 1.1E-56 T 16-09-2016 IPR011032 GroES-like Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 112 7.3E-24 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 SMART SM00829 16 363 1.8E-11 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 SUPERFAMILY SSF50129 6 191 3.2E-51 T 16-09-2016 IPR011032 GroES-like Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 PANTHER PTHR11695 19 365 3.4E-122 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 Pfam PF00107 Zinc-binding dehydrogenase 195 318 1.7E-29 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 SUPERFAMILY SSF51735 157 329 1.97E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06690 4560ba3b2d26a566fed296093ec58163 365 Gene3D G3DSA:3.40.50.720 188 307 9.2E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 310 321 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 202 207 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 SUPERFAMILY SSF50494 180 354 3.0E-41 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Gene3D G3DSA:2.40.10.10 174 257 4.2E-28 T 16-09-2016 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Gene3D G3DSA:2.40.10.10 258 347 9.0E-31 T 16-09-2016 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PIRSF PIRSF001134 1 360 7.8E-135 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Gene3D G3DSA:3.30.300.50 102 161 7.0E-8 T 16-09-2016 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Pfam PF02983 Alpha-lytic protease prodomain 102 156 1.4E-15 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Pfam PF00089 Trypsin 175 352 1.5E-11 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 281 298 1.1E-46 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 325 339 1.1E-46 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 301 324 1.1E-46 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 260 280 1.1E-46 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 200 214 1.1E-46 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 Gene3D G3DSA:3.30.300.50 48 100 2.6E-6 T 16-09-2016 Spa2297_RS06850 72474d5e715daaad809f5ab7b94e208c 360 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 50 - T 16-09-2016 IPR010916 TonB box, conserved site Spa2297_RS09835 8c229bf7fb9ba6b1a7cecfb10528a79d 140 Gene3D G3DSA:3.30.565.10 42 114 5.5E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09835 8c229bf7fb9ba6b1a7cecfb10528a79d 140 SUPERFAMILY SSF55874 43 119 1.11E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09835 8c229bf7fb9ba6b1a7cecfb10528a79d 140 Pfam PF13581 Histidine kinase-like ATPase domain 20 117 1.3E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 PANTHER PTHR30136 1 236 3.9E-149 T 16-09-2016 Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 Gene3D G3DSA:3.30.450.40 74 234 2.2E-39 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 PANTHER PTHR30136:SF18 1 236 3.9E-149 T 16-09-2016 Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 SMART SM00346 7 93 9.5E-15 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 Gene3D G3DSA:1.10.10.10 3 73 1.6E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 SUPERFAMILY SSF55781 62 234 6.34E-34 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.5E-9 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 Pfam PF01614 Bacterial transcriptional regulator 125 231 1.4E-15 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS23540 d1e46734c78339d91d9ee30eeec58b6a 238 SUPERFAMILY SSF46785 7 75 8.95E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PANTHER PTHR23501 3 478 1.5E-267 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 SUPERFAMILY SSF103473 4 199 3.79E-77 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 SUPERFAMILY SSF103473 245 469 3.79E-77 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PANTHER PTHR23501:SF91 3 478 1.5E-267 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 414 3.8E-84 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 Pfam PF07690 Major Facilitator Superfamily 17 406 7.2E-61 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 7.4E-12 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 335 355 7.4E-12 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 7.4E-12 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 7.4E-12 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 7.4E-12 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 Gene3D G3DSA:1.20.1250.20 6 198 8.4E-37 T 16-09-2016 Spa2297_RS10540 d9d9c1b67631fa28f3576caba1470818 481 Gene3D G3DSA:1.20.1250.20 268 463 4.5E-23 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 PANTHER PTHR23151:SF68 166 466 2.9E-149 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 PANTHER PTHR23151:SF68 2 135 2.9E-149 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 SUPERFAMILY SSF47005 164 207 3.92E-10 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 SUPERFAMILY SSF52777 231 466 5.34E-72 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Gene3D G3DSA:4.10.320.10 167 212 1.2E-14 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Gene3D G3DSA:2.40.50.100 3 94 1.5E-24 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Pfam PF02817 e3 binding domain 170 204 1.8E-13 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 244 466 7.8E-72 T 16-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Gene3D G3DSA:3.30.559.10 241 466 3.3E-75 T 16-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 PANTHER PTHR23151 2 135 2.9E-149 T 16-09-2016 Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 Pfam PF00364 Biotin-requiring enzyme 6 77 1.6E-16 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 SUPERFAMILY SSF51230 3 94 3.01E-24 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS16820 34f54faff893571013fbfc75d0a85528 469 PANTHER PTHR23151 166 466 2.9E-149 T 16-09-2016 Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 SUPERFAMILY SSF89095 3 152 2.88E-35 T 16-09-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 Pfam PF09424 Yqey-like protein 5 152 1.4E-46 T 16-09-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 PANTHER PTHR28055:SF1 1 152 2.3E-46 T 16-09-2016 Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 Gene3D G3DSA:1.10.10.410 94 152 2.3E-20 T 16-09-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 Gene3D G3DSA:1.10.1510.10 3 93 4.5E-26 T 16-09-2016 Spa2297_RS17820 cadb0d24885a6d60991247576a5a2541 154 PANTHER PTHR28055 1 152 2.3E-46 T 16-09-2016 Spa2297_RS03850 5118c05a435395c4243499612537559d 503 PANTHER PTHR35342:SF3 2 503 0.0 T 16-09-2016 Spa2297_RS03850 5118c05a435395c4243499612537559d 503 PANTHER PTHR35342 2 503 0.0 T 16-09-2016 Spa2297_RS03850 5118c05a435395c4243499612537559d 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 437 2.7E-139 T 16-09-2016 IPR002823 Protein of unknown function DUF112, transmembrane Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 SUPERFAMILY SSF52418 68 335 1.31E-81 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 Gene3D G3DSA:3.40.1030.10 68 333 6.5E-102 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 Pfam PF02885 Glycosyl transferase family, helical bundle domain 1 61 6.6E-17 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 SUPERFAMILY SSF47648 1 64 2.09E-16 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 3 331 1.4E-107 T 16-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 1 332 33.65 T 16-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 Gene3D G3DSA:1.20.970.10 2 65 1.1E-21 T 16-09-2016 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 Pfam PF00591 Glycosyl transferase family, a/b domain 69 322 7.9E-80 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 PANTHER PTHR11922 69 336 2.2E-95 T 16-09-2016 Spa2297_RS23975 1082268859c71a7fbed1c71bc74516f8 340 PANTHER PTHR11922:SF5 69 336 2.2E-95 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 Pfam PF05592 Bacterial alpha-L-rhamnosidase 443 995 1.3E-145 T 16-09-2016 IPR008902 Bacterial alpha-L-rhamnosidase Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307 844 999 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307 789 828 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 205 390 1.7E-43 T 16-09-2016 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 Gene3D G3DSA:2.60.120.260 441 543 2.2E-10 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307 55 357 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307 397 772 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 SUPERFAMILY SSF48208 552 997 1.19E-39 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307:SF5 844 999 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307:SF5 397 772 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307:SF5 789 828 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PANTHER PTHR33307:SF5 55 357 3.4E-221 T 16-09-2016 Spa2297_RS29620 02f8b72445d9ec7a740794ad246c0a3a 1042 PIRSF PIRSF010631 39 1041 6.7E-255 T 16-09-2016 IPR016007 Alpha-L-rhamnosidase Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 SUPERFAMILY SSF54637 17 157 8.02E-34 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 PANTHER PTHR13078 1 258 5.1E-107 T 16-09-2016 Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 PANTHER PTHR13078:SF5 1 258 5.1E-107 T 16-09-2016 Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 Pfam PF01575 MaoC like domain 162 258 1.4E-28 T 16-09-2016 IPR002539 MaoC-like domain Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 Pfam PF13452 N-terminal half of MaoC dehydratase 16 133 1.0E-9 T 16-09-2016 Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 Gene3D G3DSA:3.10.129.10 1 145 3.1E-41 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 SUPERFAMILY SSF54637 163 289 4.48E-26 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS09635 695f7fc6001de149681965a175fda2b5 292 Gene3D G3DSA:3.10.129.10 146 290 2.3E-39 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PANTHER PTHR22773:SF50 1 603 2.9E-249 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 648 2.9E-242 T 16-09-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 Pfam PF00361 Proton-conducting membrane transporter 135 423 4.4E-80 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PANTHER PTHR22773 1 603 2.9E-249 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 270 292 2.7E-10 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 426 448 2.7E-10 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 2.7E-10 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 2.7E-10 T 16-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 278 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 251 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 320 332 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 427 446 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 1.5E-59 T 16-09-2016 Spa2297_RS19250 7106850fef8f7242bf867291b98e0eb6 654 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 6.4E-24 T 16-09-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Spa2297_RS00125 378bd5ee10632c46ea7f874e9e6ea74e 173 Pfam PF01292 Prokaryotic cytochrome b561 26 152 2.5E-8 T 16-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Spa2297_RS00125 378bd5ee10632c46ea7f874e9e6ea74e 173 SUPERFAMILY SSF81342 11 173 7.85E-21 T 16-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Spa2297_RS00125 378bd5ee10632c46ea7f874e9e6ea74e 173 Gene3D G3DSA:1.20.950.20 2 173 8.6E-37 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 Gene3D G3DSA:3.50.50.60 138 330 2.4E-49 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 Gene3D G3DSA:3.30.390.30 341 459 2.6E-27 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 7.7E-137 T 16-09-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.8E-34 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.8E-34 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.8E-34 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.8E-34 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.8E-34 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 SUPERFAMILY SSF51905 7 366 1.9E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 16-09-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 9.0E-64 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 SUPERFAMILY SSF55424 338 459 9.45E-29 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 Gene3D G3DSA:3.50.50.60 9 137 1.5E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 5.5E-69 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 2.6E-23 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PIRSF PIRSF000350 1 436 5.8E-73 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PANTHER PTHR22912 1 453 4.5E-184 T 16-09-2016 Spa2297_RS09010 17b905c59973b59e656004d262b69468 462 PANTHER PTHR22912:SF125 1 453 4.5E-184 T 16-09-2016 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 SUPERFAMILY SSF53137 19 134 4.8E-50 T 16-09-2016 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 Gene3D G3DSA:3.30.420.80 11 134 1.8E-58 T 16-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 PANTHER PTHR11759 15 134 1.1E-69 T 16-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 134 34.428 T 16-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 PIRSF PIRSF002131 4 134 4.8E-54 T 16-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 16-09-2016 IPR018102 Ribosomal S11, conserved site Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 Pfam PF00411 Ribosomal protein S11 24 133 1.3E-48 T 16-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19925 abdf80cf0f3eac155398a89412d8a9de 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 16-09-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS17585 86ff14374686870fe3bc20e0824f4274 138 PANTHER PTHR41553:SF1 16 138 7.9E-24 T 16-09-2016 Spa2297_RS17585 86ff14374686870fe3bc20e0824f4274 138 Gene3D G3DSA:1.20.1250.20 48 112 3.7E-4 T 16-09-2016 Spa2297_RS17585 86ff14374686870fe3bc20e0824f4274 138 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 17 132 4.6E-34 T 16-09-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III Spa2297_RS17585 86ff14374686870fe3bc20e0824f4274 138 PANTHER PTHR41553 16 138 7.9E-24 T 16-09-2016 Spa2297_RS11860 1e12b6081093577ecd1f8587c8375366 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 333 4.0E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11860 1e12b6081093577ecd1f8587c8375366 336 PANTHER PTHR30193:SF6 23 333 1.6E-132 T 16-09-2016 Spa2297_RS11860 1e12b6081093577ecd1f8587c8375366 336 SUPERFAMILY SSF161098 92 322 6.93E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11860 1e12b6081093577ecd1f8587c8375366 336 Gene3D G3DSA:1.10.3720.10 42 324 1.7E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11860 1e12b6081093577ecd1f8587c8375366 336 PANTHER PTHR30193 23 333 1.6E-132 T 16-09-2016 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 SMART SM01217 684 753 3.5E-24 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 Gene3D G3DSA:3.40.50.1700 399 650 2.5E-58 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PANTHER PTHR30620 91 767 0.0 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 Pfam PF14310 Fibronectin type III-like domain 684 753 4.1E-17 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PANTHER PTHR30620:SF59 91 767 0.0 T 16-09-2016 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PANTHER PTHR30620 8 46 0.0 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 411 647 1.6E-42 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 33 358 2.2E-67 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 SUPERFAMILY SSF51445 10 409 1.37E-92 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 SUPERFAMILY SSF52279 411 650 1.7E-43 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 Gene3D G3DSA:3.20.20.300 11 370 6.4E-97 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 207 223 9.8E-20 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 278 296 9.8E-20 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 130 149 9.8E-20 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 107 123 9.8E-20 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PRINTS PR00133 Glycosyl hydrolase family 3 signature 176 192 9.8E-20 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS03200 a99a2a972ccd47be3075a69e2be6414e 788 PANTHER PTHR30620:SF59 8 46 0.0 T 16-09-2016 Spa2297_RS01150 2476432ad5efaf79169d78942b15fc1f 216 PANTHER PTHR23416:SF69 35 212 1.1E-64 T 16-09-2016 Spa2297_RS01150 2476432ad5efaf79169d78942b15fc1f 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 115 150 1.1E-8 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS01150 2476432ad5efaf79169d78942b15fc1f 216 PANTHER PTHR23416 35 212 1.1E-64 T 16-09-2016 Spa2297_RS01150 2476432ad5efaf79169d78942b15fc1f 216 Gene3D G3DSA:2.160.10.10 31 211 2.5E-45 T 16-09-2016 Spa2297_RS01150 2476432ad5efaf79169d78942b15fc1f 216 SUPERFAMILY SSF51161 58 206 1.52E-41 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 PANTHER PTHR30328 2 203 5.3E-54 T 16-09-2016 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 SUPERFAMILY SSF46689 17 94 2.79E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 4.9E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 4.9E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 PANTHER PTHR30328:SF29 2 203 5.3E-54 T 16-09-2016 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 Gene3D G3DSA:1.10.357.10 15 203 7.0E-30 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS14480 f748bd608a2b4cb15ef6693a4a0e952b 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 9.4E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 Gene3D G3DSA:1.10.132.20 66 185 1.7E-40 T 16-09-2016 IPR023584 Ribosome recycling factor domain Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 Pfam PF01765 Ribosome recycling factor 21 183 7.7E-58 T 16-09-2016 IPR023584 Ribosome recycling factor domain Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.746 T 16-09-2016 IPR002661 Ribosome recycling factor GO:0006412 Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 SUPERFAMILY SSF55194 3 184 1.11E-66 T 16-09-2016 IPR023584 Ribosome recycling factor domain Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 PANTHER PTHR20982 1 185 2.3E-76 T 16-09-2016 IPR002661 Ribosome recycling factor GO:0006412 Spa2297_RS23835 ba02f908934e789571a1e69c250272a3 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.1E-62 T 16-09-2016 IPR002661 Ribosome recycling factor GO:0006412 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 163 183 - T 16-09-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 Pfam PF04055 Radical SAM superfamily 163 333 2.5E-29 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 PANTHER PTHR11918:SF43 4 453 5.1E-179 T 16-09-2016 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 16 452 2.5E-144 T 16-09-2016 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 PANTHER PTHR11918 4 453 5.1E-179 T 16-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 Pfam PF00919 Uncharacterized protein family UPF0004 17 116 4.4E-27 T 16-09-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 SUPERFAMILY SSF102114 145 385 1.7E-58 T 16-09-2016 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 SMART SM00729 159 377 3.2E-59 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 14 456 67.505 T 16-09-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 Gene3D G3DSA:3.80.30.20 159 390 3.7E-83 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS24490 162852b946c21073b217d3582dc0bc65 505 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 15 451 4.4E-152 T 16-09-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 SUPERFAMILY SSF55347 213 317 2.09E-27 T 16-09-2016 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 SUPERFAMILY SSF51735 11 212 3.23E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 SUPERFAMILY SSF51735 316 372 3.23E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 Gene3D G3DSA:3.30.360.10 215 313 4.3E-26 T 16-09-2016 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 PANTHER PTHR11510:SF7 15 370 1.6E-122 T 16-09-2016 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 Pfam PF07994 Myo-inositol-1-phosphate synthase 161 369 1.3E-19 T 16-09-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 Pfam PF01658 Myo-inositol-1-phosphate synthase 214 318 4.6E-23 T 16-09-2016 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 Gene3D G3DSA:3.40.50.720 17 214 1.4E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 Gene3D G3DSA:3.40.50.720 317 375 1.4E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 PANTHER PTHR11510 15 370 1.6E-122 T 16-09-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS27375 f1cdd457278d6a8be78f759ed32d4e24 396 PIRSF PIRSF015578 6 389 2.0E-87 T 16-09-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS28340 b35c80188c7800b1e72d0ed5cc82f5bc 177 Gene3D G3DSA:3.40.630.30 3 170 8.2E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28340 b35c80188c7800b1e72d0ed5cc82f5bc 177 SUPERFAMILY SSF55729 11 169 7.77E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28340 b35c80188c7800b1e72d0ed5cc82f5bc 177 Pfam PF00583 Acetyltransferase (GNAT) family 66 144 1.3E-12 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS28340 b35c80188c7800b1e72d0ed5cc82f5bc 177 PANTHER PTHR13947 62 152 5.6E-19 T 16-09-2016 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 9.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 9.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 9.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 PANTHER PTHR26402:SF564 8 223 2.7E-99 T 16-09-2016 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 1.5E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 SMART SM00421 163 220 4.7E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 Pfam PF00072 Response regulator receiver domain 10 122 5.0E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 Gene3D G3DSA:1.10.10.10 129 222 6.2E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 SMART SM00448 8 121 2.6E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 SUPERFAMILY SSF46894 156 222 1.46E-16 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 PANTHER PTHR26402 8 223 2.7E-99 T 16-09-2016 Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 SUPERFAMILY SSF52172 7 134 6.83E-33 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS26525 b9fb04ce7b1424277c46b5b5755d5962 225 Gene3D G3DSA:3.40.50.2300 4 128 3.2E-36 T 16-09-2016 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 Gene3D G3DSA:1.10.275.10 16 104 5.5E-23 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PANTHER PTHR11444 14 469 1.9E-112 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 SMART SM00998 372 458 1.1E-17 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 SUPERFAMILY SSF48557 13 459 2.83E-78 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 Gene3D G3DSA:1.20.200.10 105 454 3.9E-79 T 16-09-2016 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PANTHER PTHR11444:SF2 14 469 1.9E-112 T 16-09-2016 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 16-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 Pfam PF10397 Adenylosuccinate lyase C-terminus 373 455 6.2E-10 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 457 2.1E-124 T 16-09-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 1.3E-11 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 1.3E-11 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 1.3E-11 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 1.3E-11 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS04575 a102e10002abb62048092c8f8db17019 480 Pfam PF00206 Lyase 46 303 1.1E-18 T 16-09-2016 IPR022761 Fumarate lyase, N-terminal Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SUPERFAMILY SSF52317 832 1055 3.43E-49 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SUPERFAMILY SSF50952 406 482 1.31E-23 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SUPERFAMILY SSF50952 57 371 1.31E-23 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Gene3D G3DSA:3.40.50.880 831 1054 1.0E-40 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Gene3D G3DSA:2.60.40.670 509 590 3.8E-20 T 16-09-2016 IPR000601 PKD domain Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Pfam PF06283 Trehalose utilisation 833 1044 1.1E-81 T 16-09-2016 IPR029010 ThuA-like domain Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Pfam PF00801 PKD domain 511 578 3.7E-16 T 16-09-2016 IPR000601 PKD domain Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Pfam PF06439 Domain of Unknown Function (DUF1080) 1058 1233 3.2E-44 T 16-09-2016 IPR010496 Domain of unknown function DUF1080 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SUPERFAMILY SSF49299 506 590 5.36E-21 T 16-09-2016 IPR000601 PKD domain Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SUPERFAMILY SSF49785 697 824 1.87E-24 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Pfam PF03422 Carbohydrate binding module (family 6) 702 824 1.7E-30 T 16-09-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Pfam PF07995 Glucose / Sorbosone dehydrogenase 71 480 1.6E-38 T 16-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SMART SM00606 694 825 1.3E-45 T 16-09-2016 IPR006584 Cellulose binding, type IV GO:0030246 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 SMART SM00089 508 590 1.1E-23 T 16-09-2016 IPR022409 PKD/Chitinase domain Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Gene3D G3DSA:2.120.10.30 35 508 8.8E-104 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 Gene3D G3DSA:2.60.120.260 697 824 2.0E-34 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 PANTHER PTHR19328 364 506 1.3E-87 T 16-09-2016 Spa2297_RS27370 c8f7a8aae553700b25163ac760cc1849 1237 PANTHER PTHR19328 40 348 1.3E-87 T 16-09-2016 Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 Gene3D G3DSA:3.30.450.40 80 151 2.2E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 Gene3D G3DSA:3.30.450.40 153 214 1.7E-6 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 Gene3D G3DSA:1.10.10.10 5 76 2.7E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 SMART SM00346 6 93 7.8E-16 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 PANTHER PTHR30136:SF14 4 215 2.6E-55 T 16-09-2016 Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 SUPERFAMILY SSF55781 81 214 4.51E-19 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 SUPERFAMILY SSF46785 7 76 2.35E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 PANTHER PTHR30136 4 215 2.6E-55 T 16-09-2016 Spa2297_RS12590 a392da7b46a154eca8320765be118049 215 Pfam PF09339 IclR helix-turn-helix domain 8 58 1.6E-14 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 191 4.5E-29 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 Gene3D G3DSA:1.10.10.60 14 62 1.2E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 PANTHER PTHR30328:SF2 1 202 5.9E-65 T 16-09-2016 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 Gene3D G3DSA:1.10.357.10 64 201 1.3E-43 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 9.7E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 SUPERFAMILY SSF46689 15 77 2.52E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 PANTHER PTHR30328 1 202 5.9E-65 T 16-09-2016 Spa2297_RS30865 2d1a7031cf7b118ea2d5baabaa5397ae 206 SUPERFAMILY SSF48498 84 199 1.74E-27 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 16-09-2016 IPR030659 SecY conserved site Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.65 T 16-09-2016 IPR026593 Protein translocase subunit SecY Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PIRSF PIRSF004557 1 437 6.3E-124 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 Pfam PF00344 SecY translocase 73 420 3.6E-116 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 16-09-2016 IPR030659 SecY conserved site Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 SUPERFAMILY SSF103491 2 427 1.83E-125 T 16-09-2016 IPR023201 SecY subunit domain Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PANTHER PTHR10906 1 437 2.4E-204 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 6.1E-107 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 Gene3D G3DSA:1.10.3370.10 2 437 1.7E-157 T 16-09-2016 IPR023201 SecY subunit domain Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 PANTHER PTHR10906:SF2 1 437 2.4E-204 T 16-09-2016 Spa2297_RS19895 ded79afb215a747fb73bc40ed267bb03 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 2.2E-153 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 54 72 - T 16-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 SUPERFAMILY SSF51419 29 279 3.36E-53 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 176 189 3.6E-10 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 74 86 3.6E-10 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 267 286 3.6E-10 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 54 72 3.6E-10 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 SUPERFAMILY SSF50621 258 396 1.05E-20 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 294 390 9.8E-9 T 16-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PANTHER PTHR11482 30 392 2.3E-94 T 16-09-2016 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 277 1.5E-41 T 16-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PANTHER PTHR11482:SF6 30 392 2.3E-94 T 16-09-2016 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01182 Ornithine decarboxylase signature 126 148 9.5E-9 T 16-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01182 Ornithine decarboxylase signature 26 50 9.5E-9 T 16-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01182 Ornithine decarboxylase signature 96 120 9.5E-9 T 16-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01182 Ornithine decarboxylase signature 52 79 9.5E-9 T 16-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 PRINTS PR01182 Ornithine decarboxylase signature 337 347 9.5E-9 T 16-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 Gene3D G3DSA:2.40.37.10 262 395 9.6E-18 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS25385 369d818126cd4df5075b78103e1a78b5 405 Gene3D G3DSA:3.20.20.10 36 261 7.1E-53 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS00655 0d67264413f964552543e337510de272 671 SUPERFAMILY SSF48452 390 523 3.68E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00655 0d67264413f964552543e337510de272 671 Gene3D G3DSA:3.40.50.300 19 73 7.9E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00655 0d67264413f964552543e337510de272 671 PRINTS PR00364 Disease resistance protein signature 31 46 9.3E-7 T 16-09-2016 Spa2297_RS00655 0d67264413f964552543e337510de272 671 PRINTS PR00364 Disease resistance protein signature 100 114 9.3E-7 T 16-09-2016 Spa2297_RS00655 0d67264413f964552543e337510de272 671 PRINTS PR00364 Disease resistance protein signature 194 208 9.3E-7 T 16-09-2016 Spa2297_RS00655 0d67264413f964552543e337510de272 671 SUPERFAMILY SSF52540 5 222 1.65E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00655 0d67264413f964552543e337510de272 671 Gene3D G3DSA:1.25.40.10 386 484 1.1E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00655 0d67264413f964552543e337510de272 671 Gene3D G3DSA:1.25.40.10 491 620 2.3E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 Gene3D G3DSA:1.10.630.10 23 403 4.5E-100 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 SUPERFAMILY SSF48264 9 403 1.44E-75 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 159 174 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 95 106 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 196 218 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 294 321 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 352 363 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 343 352 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 142 158 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 322 337 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PRINTS PR00359 B-class P450 signature 275 286 1.1E-42 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 Pfam PF00067 Cytochrome P450 276 372 3.8E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS04360 46dcdb4776e0358778cb51bb8ff3fbac 403 PANTHER PTHR11712 3 403 1.4E-108 T 16-09-2016 Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 253 1.4E-53 T 16-09-2016 Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 Gene3D G3DSA:3.40.50.720 15 255 2.9E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 2.8E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 SUPERFAMILY SSF51735 17 254 1.05E-68 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PANTHER PTHR24322 167 199 2.4E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PANTHER PTHR24322 22 150 2.4E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 9.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 9.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 9.1E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26445 1548d30107e2744acb012b79b9a15496 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 203 0.0017 T 16-09-2016 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 SMART SM00490 579 670 8.0E-4 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 Gene3D G3DSA:3.40.50.300 542 706 3.5E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 PANTHER PTHR10799:SF693 264 391 9.5E-246 T 16-09-2016 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 PANTHER PTHR10799:SF693 409 741 9.5E-246 T 16-09-2016 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 Pfam PF00271 Helicase conserved C-terminal domain 551 670 1.6E-7 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 SUPERFAMILY SSF52540 413 471 7.29E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 SUPERFAMILY SSF52540 540 704 7.29E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 Pfam PF00176 SNF2 family N-terminal domain 301 526 6.6E-22 T 16-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 SMART SM00487 279 476 1.0E-23 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 PANTHER PTHR10799 264 391 9.5E-246 T 16-09-2016 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 PANTHER PTHR10799 409 741 9.5E-246 T 16-09-2016 Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 SUPERFAMILY SSF52540 276 470 1.55E-36 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 Gene3D G3DSA:3.40.50.300 282 464 4.5E-17 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21480 846aaf2abea8ae7a1e00bfb84bb3dd65 747 Gene3D G3DSA:1.10.150.20 71 113 5.1E-6 T 16-09-2016 Spa2297_RS27185 e5cb1cd15947763f3f5dff3572bc9696 211 Pfam PF09335 SNARE associated Golgi protein 60 171 8.7E-14 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS27185 e5cb1cd15947763f3f5dff3572bc9696 211 PANTHER PTHR30353 14 206 1.7E-32 T 16-09-2016 IPR032818 DedA family Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 SUPERFAMILY SSF50475 16 166 8.83E-44 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 Gene3D G3DSA:2.30.110.10 15 164 3.6E-54 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 PANTHER PTHR30466 10 169 1.7E-71 T 16-09-2016 Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 PANTHER PTHR30466:SF5 10 169 1.7E-71 T 16-09-2016 Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 Pfam PF01613 Flavin reductase like domain 22 167 3.8E-36 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS03605 8a82274d991733a6579cf58653d683c3 169 SMART SM00903 22 166 5.5E-49 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS21140 9ac2d9a0871b67d21c7e2e324921494e 440 PANTHER PTHR11706 25 236 8.1E-111 T 16-09-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 Spa2297_RS21140 9ac2d9a0871b67d21c7e2e324921494e 440 Pfam PF01566 Natural resistance-associated macrophage protein 48 409 4.4E-36 T 16-09-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 Spa2297_RS21140 9ac2d9a0871b67d21c7e2e324921494e 440 PANTHER PTHR11706:SF3 25 236 8.1E-111 T 16-09-2016 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 203 2.9E-67 T 16-09-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 SUPERFAMILY SSF53328 11 210 4.19E-58 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 200 29.804 T 16-09-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 PANTHER PTHR10520 8 201 9.4E-81 T 16-09-2016 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 Gene3D G3DSA:3.40.50.170 11 207 4.4E-69 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 Pfam PF00551 Formyl transferase 11 194 1.4E-52 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS20320 8c2665e80138b10c8c60983ae2191ed5 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 146 169 - T 16-09-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 SMART SM00382 33 222 9.3E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 Gene3D G3DSA:3.40.50.300 8 230 2.3E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 17 198 1.0E-63 T 16-09-2016 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 Pfam PF00005 ABC transporter 26 169 1.5E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 PANTHER PTHR24220:SF66 9 249 7.4E-94 T 16-09-2016 Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 SUPERFAMILY SSF52540 8 229 5.22E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13750 152b8aaf3ea67708996f8c05fbd11980 252 PANTHER PTHR24220 9 249 7.4E-94 T 16-09-2016 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SMART SM00388 217 275 3.1E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SMART SM00304 157 216 7.9E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 Pfam PF00672 HAMP domain 138 212 5.6E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 Gene3D G3DSA:3.30.565.10 263 412 3.1E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SMART SM00387 313 414 2.9E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 412 1.5E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 Gene3D G3DSA:1.10.287.130 207 262 1.3E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 275 2.2E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 PANTHER PTHR24423 74 96 1.1E-39 T 16-09-2016 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 PANTHER PTHR24423 151 414 1.1E-39 T 16-09-2016 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SUPERFAMILY SSF55874 264 412 2.1E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SUPERFAMILY SSF158472 158 213 6.67E-5 T 16-09-2016 Spa2297_RS22410 bcad43e000511fd1c71657ef99936309 414 SUPERFAMILY SSF47384 201 276 1.02E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.1E-15 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 Gene3D G3DSA:1.10.10.10 5 87 3.3E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 Gene3D G3DSA:3.40.190.10 91 182 2.0E-19 T 16-09-2016 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 SUPERFAMILY SSF46785 4 113 2.0E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 PANTHER PTHR30346:SF2 2 298 5.6E-111 T 16-09-2016 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 Gene3D G3DSA:3.40.190.10 183 269 2.6E-27 T 16-09-2016 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 SUPERFAMILY SSF53850 91 297 2.81E-34 T 16-09-2016 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 PANTHER PTHR30346 2 298 5.6E-111 T 16-09-2016 Spa2297_RS11200 94e38ef481d663e060252e1abcc786c5 300 Pfam PF03466 LysR substrate binding domain 91 296 7.0E-42 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 PANTHER PTHR10515 3 427 7.6E-190 T 16-09-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Pfam PF00591 Glycosyl transferase family, a/b domain 79 287 7.2E-34 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 PANTHER PTHR10515:SF0 3 427 7.6E-190 T 16-09-2016 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 SMART SM00941 336 410 2.3E-33 T 16-09-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Gene3D G3DSA:1.20.970.10 3 69 1.5E-26 T 16-09-2016 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 68 6.7E-17 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 408 6.7E-167 T 16-09-2016 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 PIRSF PIRSF000478 2 426 1.2E-150 T 16-09-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 SUPERFAMILY SSF52418 72 318 4.06E-81 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 SUPERFAMILY SSF54680 324 426 1.83E-25 T 16-09-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 SUPERFAMILY SSF47648 3 71 6.28E-20 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Gene3D G3DSA:3.90.1170.30 320 411 3.8E-31 T 16-09-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 112 127 - T 16-09-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 409 1.9E-23 T 16-09-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Spa2297_RS20700 e7f6ef39b6ca81bfbc237809ee9717de 427 Gene3D G3DSA:3.40.1030.10 72 319 6.0E-108 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 Gene3D G3DSA:1.10.3140.10 1 141 1.1E-40 T 16-09-2016 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 270 1.5E-93 T 16-09-2016 IPR024674 HpaB/PvcC/4-BUDH N-terminal Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 SUPERFAMILY SSF56645 1 272 7.2E-79 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 PANTHER PTHR36117 1 456 8.8E-136 T 16-09-2016 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 PIRSF PIRSF000331 1 486 5.2E-140 T 16-09-2016 IPR004925 HpaB/PvcC/4-BUDH Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 Gene3D G3DSA:2.40.110.10 146 263 2.0E-48 T 16-09-2016 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 281 468 1.6E-49 T 16-09-2016 IPR024719 HpaB/PvcC/4-BUDH C-terminal Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 Gene3D G3DSA:1.20.140.10 264 468 3.2E-36 T 16-09-2016 Spa2297_RS23930 e35ca7b5b3c21e42b3745e1074c817b5 498 SUPERFAMILY SSF47203 262 481 1.57E-42 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS25575 214cb1f482e0fbebba9c348e629aeb1b 166 SUPERFAMILY SSF52540 30 156 1.09E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25575 214cb1f482e0fbebba9c348e629aeb1b 166 Gene3D G3DSA:3.40.50.300 32 158 2.2E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25575 214cb1f482e0fbebba9c348e629aeb1b 166 PANTHER PTHR11711 1 159 1.3E-52 T 16-09-2016 Spa2297_RS25575 214cb1f482e0fbebba9c348e629aeb1b 166 Pfam PF03029 Conserved hypothetical ATP binding protein 13 158 3.5E-22 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS25575 214cb1f482e0fbebba9c348e629aeb1b 166 PANTHER PTHR11711:SF117 1 159 1.3E-52 T 16-09-2016 Spa2297_RS20255 5bff4833cfe1cafb95fc0dd133189241 324 PANTHER PTHR11440 151 208 4.2E-15 T 16-09-2016 Spa2297_RS20255 5bff4833cfe1cafb95fc0dd133189241 324 Gene3D G3DSA:3.40.50.1820 100 300 2.5E-37 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20255 5bff4833cfe1cafb95fc0dd133189241 324 Pfam PF00561 alpha/beta hydrolase fold 106 208 7.9E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS20255 5bff4833cfe1cafb95fc0dd133189241 324 SUPERFAMILY SSF53474 105 259 1.39E-29 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 Gene3D G3DSA:3.40.50.720 184 303 5.8E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 SUPERFAMILY SSF50129 311 361 1.93E-8 T 16-09-2016 IPR011032 GroES-like Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 149 3.3E-26 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 SMART SM00829 12 362 2.8E-4 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 362 5.9E-211 T 16-09-2016 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 SUPERFAMILY SSF50129 4 187 3.96E-54 T 16-09-2016 IPR011032 GroES-like Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 PANTHER PTHR11695 17 362 7.3E-257 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 SUPERFAMILY SSF51735 153 327 5.61E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 Gene3D G3DSA:3.90.180.10 3 183 5.3E-55 T 16-09-2016 IPR011032 GroES-like Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 Pfam PF00107 Zinc-binding dehydrogenase 191 318 5.8E-31 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS30010 fc2a80fcf0198b710b91d6f089f6a9ef 362 PANTHER PTHR11695:SF417 17 362 7.3E-257 T 16-09-2016 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 SUPERFAMILY SSF52172 1 186 2.13E-38 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 Gene3D G3DSA:1.10.10.10 128 226 9.1E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 PANTHER PTHR26402 1 227 4.5E-112 T 16-09-2016 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 SMART SM00448 1 113 1.9E-38 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-36 T 16-09-2016 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 SMART SM00862 151 223 4.1E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 1.1E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS24450 722211c30f1bef8a6f4eb84e1ec5871c 228 PANTHER PTHR26402:SF518 1 227 4.5E-112 T 16-09-2016 Spa2297_RS27760 0204be45a14b3d19060546a119fb297c 218 PANTHER PTHR35010 1 218 6.8E-47 T 16-09-2016 Spa2297_RS27760 0204be45a14b3d19060546a119fb297c 218 Gene3D G3DSA:3.30.450.20 30 63 3.9E-4 T 16-09-2016 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 SUPERFAMILY SSF47413 12 69 3.66E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 Gene3D G3DSA:1.10.260.40 12 69 3.1E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 PANTHER PTHR10245:SF7 11 270 1.5E-35 T 16-09-2016 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 PANTHER PTHR10245 11 270 1.5E-35 T 16-09-2016 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 Pfam PF13560 Helix-turn-helix domain 16 71 5.2E-9 T 16-09-2016 Spa2297_RS25895 968ab7823bc1f2c96df518b1fc65c2bb 272 SMART SM00530 18 73 9.5E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 PANTHER PTHR21235:SF1 7 216 2.9E-89 T 16-09-2016 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 SUPERFAMILY SSF52317 8 214 1.63E-53 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 10 214 1.3E-62 T 16-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 Pfam PF00117 Glutamine amidotransferase class-I 12 207 1.5E-17 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 9 215 31.294 T 16-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 PANTHER PTHR21235 7 216 2.9E-89 T 16-09-2016 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 PIRSF PIRSF000495 8 216 2.1E-66 T 16-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 Spa2297_RS08365 ba6464cabc69226610471e275a1f47f3 216 Gene3D G3DSA:3.40.50.880 8 214 3.3E-74 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 SUPERFAMILY SSF52172 6 134 1.34E-28 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 Pfam PF00072 Response regulator receiver domain 9 120 1.6E-23 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 Gene3D G3DSA:3.40.50.2300 6 155 9.8E-37 T 16-09-2016 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 PANTHER PTHR26402 7 209 6.8E-68 T 16-09-2016 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 PANTHER PTHR26402:SF151 7 209 6.8E-68 T 16-09-2016 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 4.1E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.3E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.3E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.3E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 SMART SM00448 7 120 4.5E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 SUPERFAMILY SSF46894 144 214 1.09E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 SMART SM00421 153 210 5.3E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16880 2e75262e5cc2c10c91573c75f25b42db 218 Gene3D G3DSA:1.10.10.10 156 212 2.1E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07705 fb3d2f1c805b7d1b7cac97838e751b5e 183 Pfam PF01966 HD domain 28 105 6.1E-6 T 16-09-2016 IPR006674 HD domain Spa2297_RS07705 fb3d2f1c805b7d1b7cac97838e751b5e 183 SUPERFAMILY SSF109604 22 133 5.5E-14 T 16-09-2016 Spa2297_RS07705 fb3d2f1c805b7d1b7cac97838e751b5e 183 Gene3D G3DSA:1.10.3210.10 23 100 2.6E-7 T 16-09-2016 IPR006674 HD domain Spa2297_RS07705 fb3d2f1c805b7d1b7cac97838e751b5e 183 TIGRFAM TIGR00277 HDIG: HDIG domain 28 98 8.5E-8 T 16-09-2016 IPR006675 HDIG domain Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 Gene3D G3DSA:3.40.50.1000 199 274 4.2E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 Gene3D G3DSA:3.40.50.1000 17 92 4.2E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 124 1.2E-22 T 16-09-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 PANTHER PTHR19288:SF3 10 284 4.9E-83 T 16-09-2016 Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 Gene3D G3DSA:3.40.50.10410 93 198 7.5E-27 T 16-09-2016 IPR023215 Nitrophenylphosphatase-like domain Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 Pfam PF13242 HAD-hyrolase-like 200 271 6.1E-14 T 16-09-2016 Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 PANTHER PTHR19288 10 284 4.9E-83 T 16-09-2016 Spa2297_RS07070 6ecce58c0ca92b53b817677e46feadcc 343 SUPERFAMILY SSF56784 20 274 1.8E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS20455 99d51c7f00d47d358f73ed25a3d2869c 156 Pfam PF04138 GtrA-like protein 11 130 8.4E-21 T 16-09-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 SUPERFAMILY SSF55124 527 655 1.23E-21 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Gene3D G3DSA:3.50.50.60 10 110 8.1E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 SUPERFAMILY SSF51905 153 318 1.53E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Gene3D G3DSA:3.30.413.10 646 782 2.7E-34 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 299 7.3E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PANTHER PTHR11493:SF52 422 849 7.4E-254 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 11 815 0.0 T 16-09-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UniPathway: UPA00653 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 693 709 - T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.0E-9 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.0E-9 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 3.0E-9 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.0E-9 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.0E-9 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PANTHER PTHR11493 7 261 7.4E-254 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 SUPERFAMILY SSF51905 8 193 3.18E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Gene3D G3DSA:3.50.50.60 111 238 1.5E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PANTHER PTHR11493:SF52 7 261 7.4E-254 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PANTHER PTHR11493 422 849 7.4E-254 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Gene3D G3DSA:3.50.50.60 239 319 8.8E-11 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 2.9E-7 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 2.9E-7 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.9E-7 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 2.9E-7 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 574 635 3.3E-9 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 646 782 6.6E-20 T 16-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 Pfam PF04324 BFD-like [2Fe-2S] binding domain 426 472 5.9E-11 T 16-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 SUPERFAMILY SSF56014 647 821 1.23E-50 T 16-09-2016 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00397 Sirohaem Fe-binding site signature 693 711 3.8E-6 T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PRINTS PR00397 Sirohaem Fe-binding site signature 650 668 3.8E-6 T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS10485 a49ac9243cfb28991ee038393155f074 870 PIRSF PIRSF037149 3 849 0.0 T 16-09-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 Gene3D G3DSA:3.40.50.150 231 402 2.2E-19 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 191 9.1E-23 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 SUPERFAMILY SSF53335 214 408 2.09E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 Gene3D G3DSA:3.40.1010.10 11 112 2.0E-26 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 PIRSF PIRSF036428 6 411 5.1E-139 T 16-09-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 PANTHER PTHR14741:SF34 194 364 1.6E-44 T 16-09-2016 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 Gene3D G3DSA:3.30.950.10 113 217 5.8E-24 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 242 380 1.2E-4 T 16-09-2016 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 SUPERFAMILY SSF53790 11 214 3.05E-39 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 240 361 2.5E-32 T 16-09-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 PANTHER PTHR14741 194 364 1.6E-44 T 16-09-2016 Spa2297_RS00615 aaf0b4531a4cca99705b55dfb59d1bb3 419 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 11 211 7.9E-49 T 16-09-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 PANTHER PTHR12993:SF12 1 292 7.1E-171 T 16-09-2016 Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 5 290 64.652 T 16-09-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 289 6.7E-150 T 16-09-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 PANTHER PTHR12993 1 292 7.1E-171 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 SUPERFAMILY SSF102588 4 290 4.71E-73 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 Gene3D G3DSA:3.40.50.10320 4 291 1.7E-83 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS21005 fb28fbad3d28b888eed376f59fd988af 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 8.3E-26 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 PIRSF PIRSF039085 1 253 2.5E-126 T 16-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 SMART SM00382 29 226 5.7E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 Gene3D G3DSA:3.40.50.300 4 250 2.3E-84 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 PANTHER PTHR24220 6 253 6.8E-140 T 16-09-2016 Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 SUPERFAMILY SSF52540 4 248 1.13E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 Pfam PF00005 ABC transporter 20 178 4.6E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS22255 a9a3c9aa9638fb4060e6c469376d4a5d 253 PANTHER PTHR24220:SF327 6 253 6.8E-140 T 16-09-2016 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 PANTHER PTHR11851:SF144 11 449 1.0E-74 T 16-09-2016 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 PANTHER PTHR11851 11 449 1.0E-74 T 16-09-2016 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 Pfam PF05193 Peptidase M16 inactive domain 192 374 1.5E-21 T 16-09-2016 IPR007863 Peptidase M16, C-terminal Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 SUPERFAMILY SSF63411 252 452 4.89E-21 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 Pfam PF00675 Insulinase (Peptidase family M16) 39 155 1.3E-11 T 16-09-2016 IPR011765 Peptidase M16, N-terminal Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 SUPERFAMILY SSF63411 13 245 1.07E-37 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 Gene3D G3DSA:3.30.830.10 29 233 9.6E-32 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS24750 e1d897d06316851aa395c1b6e8caacca 462 Gene3D G3DSA:3.30.830.10 253 442 3.0E-11 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 SMART SM00866 92 227 6.2E-15 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 Gene3D G3DSA:1.10.10.10 4 68 8.3E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 SUPERFAMILY SSF64288 55 229 1.51E-24 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PANTHER PTHR11751:SF394 1 70 1.2E-24 T 16-09-2016 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 Pfam PF07702 UTRA domain 98 226 1.7E-25 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 Gene3D G3DSA:3.40.1410.10 69 227 1.4E-20 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 SMART SM00345 8 67 1.9E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PANTHER PTHR11751 222 243 1.2E-24 T 16-09-2016 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PANTHER PTHR11751 1 70 1.2E-24 T 16-09-2016 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 SUPERFAMILY SSF46785 4 70 3.24E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PANTHER PTHR11751:SF394 222 243 1.2E-24 T 16-09-2016 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 67 2.8E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.6E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17370 f2778ecaca51d261c00d5e2ddb18a47b 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.6E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 Pfam PF00574 Clp protease 20 200 9.5E-57 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 2.2E-28 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 2.2E-28 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 2.2E-28 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 2.2E-28 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 2.2E-28 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PANTHER PTHR10381:SF7 1 201 1.5E-99 T 16-09-2016 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 201 32.323 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 SUPERFAMILY SSF52096 11 200 6.63E-46 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 Gene3D G3DSA:3.90.226.10 11 199 3.0E-57 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS04500 f20fe5203a3754c7a88f5fdb5ffd526a 211 PANTHER PTHR10381 1 201 1.5E-99 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS22390 fdff459a9a28149de9ee3af263f639a0 312 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 21 295 6.3E-96 T 16-09-2016 IPR025859 P-aminobenzoate N-oxygenase AurF Spa2297_RS22390 fdff459a9a28149de9ee3af263f639a0 312 SUPERFAMILY SSF47240 38 225 5.83E-12 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 PANTHER PTHR11624 360 693 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 SMART SM00861 373 554 6.6E-62 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 PANTHER PTHR11624 14 333 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Gene3D G3DSA:3.40.50.970 16 343 5.9E-108 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 SUPERFAMILY SSF52518 360 555 4.82E-61 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Pfam PF02780 Transketolase, C-terminal domain 574 681 3.5E-11 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Gene3D G3DSA:3.40.50.920 563 689 1.4E-43 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 PANTHER PTHR11624:SF1 14 333 0.0 T 16-09-2016 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 18 357 3.3E-132 T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 SUPERFAMILY SSF52518 15 343 9.91E-100 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 PANTHER PTHR11624:SF1 360 693 0.0 T 16-09-2016 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Gene3D G3DSA:3.40.50.970 352 559 3.1E-69 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 Pfam PF02779 Transketolase, pyrimidine binding domain 372 551 9.9E-42 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 SUPERFAMILY SSF52922 560 690 8.77E-36 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 TIGRFAM TIGR00232 tktlase_bact: transketolase 20 687 2.6E-227 T 16-09-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Spa2297_RS27710 964e56cac616e7d73c6110358675680e 694 ProSitePatterns PS00802 Transketolase signature 2. 493 509 - T 16-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS08455 e2ed5f995fa6aa007e899fd83a530d6a 375 Pfam PF00924 Mechanosensitive ion channel 135 330 2.1E-33 T 16-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Spa2297_RS08455 e2ed5f995fa6aa007e899fd83a530d6a 375 Gene3D G3DSA:2.30.30.60 195 243 6.0E-13 T 16-09-2016 Spa2297_RS08455 e2ed5f995fa6aa007e899fd83a530d6a 375 PANTHER PTHR30566:SF10 1 375 3.1E-192 T 16-09-2016 Spa2297_RS08455 e2ed5f995fa6aa007e899fd83a530d6a 375 PANTHER PTHR30566 1 375 3.1E-192 T 16-09-2016 Spa2297_RS08455 e2ed5f995fa6aa007e899fd83a530d6a 375 SUPERFAMILY SSF50182 179 244 7.19E-17 T 16-09-2016 IPR010920 LSM domain Spa2297_RS24140 c523411fdc8aa5b86ab7c4e5bfddc220 161 Pfam PF14530 Domain of unknown function (DUF4439) 11 141 3.9E-45 T 16-09-2016 IPR029447 Domain of unknown function DUF4439 Spa2297_RS24140 c523411fdc8aa5b86ab7c4e5bfddc220 161 Gene3D G3DSA:1.20.1260.10 5 131 2.8E-45 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS24140 c523411fdc8aa5b86ab7c4e5bfddc220 161 SUPERFAMILY SSF47240 5 141 7.77E-40 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 Pfam PF00494 Squalene/phytoene synthase 19 286 4.1E-68 T 16-09-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 PANTHER PTHR31480:SF8 12 296 1.2E-135 T 16-09-2016 Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 PANTHER PTHR31480 12 296 1.2E-135 T 16-09-2016 Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 18 293 1.3E-99 T 16-09-2016 IPR017827 Squalene synthase HpnC Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 SUPERFAMILY SSF48576 17 298 9.49E-61 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28155 b682d2cc8fe8cb2173330154cc1b2963 300 Gene3D G3DSA:1.10.600.10 16 289 2.6E-50 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 121 1.7E-24 T 16-09-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 105 2.9E-13 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 84 3.0E-10 T 16-09-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 122 6.1E-21 T 16-09-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 SUPERFAMILY SSF56214 3 122 1.31E-24 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 123 22.378 T 16-09-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS20000 4745b0a9e58889323bf4c47bf2b0d538 123 Gene3D G3DSA:3.90.470.20 1 122 9.9E-40 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 SUPERFAMILY SSF100950 2 256 3.16E-87 T 16-09-2016 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 13 245 1.0E-75 T 16-09-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 16-09-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 3.2E-24 T 16-09-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 PANTHER PTHR11280 3 259 8.2E-116 T 16-09-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 Gene3D G3DSA:3.40.50.1360 2 256 9.7E-91 T 16-09-2016 Spa2297_RS22160 a5c80880587555fb527d49c3cde0fac8 261 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 39.281 T 16-09-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 Spa2297_RS23365 e8aeefb98db20c212f94a33843a503a2 308 PIRSF PIRSF000196 1 308 2.7E-112 T 16-09-2016 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 Spa2297_RS23365 e8aeefb98db20c212f94a33843a503a2 308 Pfam PF01619 Proline dehydrogenase 45 300 7.0E-31 T 16-09-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 Spa2297_RS23365 e8aeefb98db20c212f94a33843a503a2 308 Gene3D G3DSA:3.20.20.220 35 303 5.2E-67 T 16-09-2016 IPR029041 FAD-linked oxidoreductase-like Spa2297_RS23365 e8aeefb98db20c212f94a33843a503a2 308 SUPERFAMILY SSF51730 35 304 2.28E-67 T 16-09-2016 IPR029041 FAD-linked oxidoreductase-like Spa2297_RS01470 374c62dd329e6c6710ab763544cc44af 301 PANTHER PTHR36151:SF3 9 259 1.5E-49 T 16-09-2016 Spa2297_RS01470 374c62dd329e6c6710ab763544cc44af 301 PANTHER PTHR36151 9 259 1.5E-49 T 16-09-2016 Spa2297_RS01470 374c62dd329e6c6710ab763544cc44af 301 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 52 272 2.7E-49 T 16-09-2016 IPR018713 Domain of unknown function DUF2236 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 PIRSF PIRSF001549 1 419 8.0E-105 T 16-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Gene3D G3DSA:3.40.50.800 324 415 1.3E-26 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 PANTHER PTHR11476 3 420 8.8E-191 T 16-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 406 3.1E-133 T 16-09-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 SUPERFAMILY SSF55681 4 315 3.19E-81 T 16-09-2016 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 PANTHER PTHR11476:SF9 3 420 8.8E-191 T 16-09-2016 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Pfam PF03129 Anticodon binding domain 331 417 9.1E-12 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 5.9E-41 T 16-09-2016 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 SUPERFAMILY SSF52954 326 419 8.51E-23 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 31.188 T 16-09-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Gene3D G3DSA:3.30.930.10 219 319 6.6E-82 T 16-09-2016 Spa2297_RS05705 ea296387edda0b876e7f01fde2ad79ba 420 Gene3D G3DSA:3.30.930.10 3 185 6.6E-82 T 16-09-2016 Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Gene3D G3DSA:3.30.1050.10 315 406 1.1E-15 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Hamap MF_01812 UPF0256 protein . 1 418 51.909 T 16-09-2016 IPR022902 Uncharacterised protein family UPF0256 Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 SUPERFAMILY SSF55718 314 418 1.33E-21 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Pfam PF13527 Acetyltransferase (GNAT) domain 9 135 1.8E-30 T 16-09-2016 Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 PANTHER PTHR37817:SF1 1 418 1.8E-99 T 16-09-2016 Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 SUPERFAMILY SSF55729 7 313 1.83E-62 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Pfam PF13530 Sterol carrier protein domain 187 415 6.3E-51 T 16-09-2016 IPR025559 Enhanced intracellular survival protein domain Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Gene3D G3DSA:3.40.630.30 4 141 1.6E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 PANTHER PTHR37817 1 418 1.8E-99 T 16-09-2016 Spa2297_RS15255 d8639868155d5e48cff04ff0a8127a5c 418 Gene3D G3DSA:3.40.630.30 142 301 2.8E-34 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04845 a2192c095c91e0e07641b59ec4ca2443 339 SUPERFAMILY SSF81995 3 64 8.63E-5 T 16-09-2016 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 16-09-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 1.5E-111 T 16-09-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 Gene3D G3DSA:3.40.50.1240 5 253 2.4E-87 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 127 6.6E-26 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 133 211 7.6E-5 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 PANTHER PTHR11931 4 253 1.7E-154 T 16-09-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 SUPERFAMILY SSF53254 6 224 5.3E-71 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 42.116 T 16-09-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 Spa2297_RS15145 261b72c1795f035bc183caf3d403695f 253 SMART SM00855 7 193 1.6E-23 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 238 250 4.1E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 208 222 4.1E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 222 238 4.1E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 Pfam PF00196 Bacterial regulatory proteins, luxR family 210 261 9.2E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 SUPERFAMILY SSF46894 210 268 8.5E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 Gene3D G3DSA:3.30.450.40 6 147 2.4E-7 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 SMART SM00421 205 262 1.3E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 SUPERFAMILY SSF55781 6 146 2.55E-9 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 PANTHER PTHR26402 171 268 3.5E-13 T 16-09-2016 Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 Gene3D G3DSA:1.10.10.10 210 268 4.3E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26260 92be0f4cccbc8bb261fad438d6389564 269 Pfam PF01590 GAF domain 49 137 2.8E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS29820 72d1ab8c2f00d9d3747b9a81a85d841c 123 PANTHER PTHR36221 1 123 7.2E-32 T 16-09-2016 Spa2297_RS29820 72d1ab8c2f00d9d3747b9a81a85d841c 123 Pfam PF05331 Protein of unknown function (DUF742) 12 123 2.9E-30 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953 370 399 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 Gene3D G3DSA:3.60.21.10 178 521 1.1E-8 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953:SF28 370 399 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953:SF28 66 217 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 SUPERFAMILY SSF56300 175 513 8.44E-26 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 69 165 1.9E-32 T 16-09-2016 IPR032093 Phospholipase D, N-terminal Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953:SF28 240 349 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953 66 217 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 PANTHER PTHR22953 240 349 7.3E-129 T 16-09-2016 Spa2297_RS09540 9d6797e1a16bd5f8479bf8b69719cd6c 550 Pfam PF09423 PhoD-like phosphatase 178 519 4.1E-105 T 16-09-2016 IPR018946 Alkaline phosphatase D-related Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 PANTHER PTHR30173 1 186 1.8E-65 T 16-09-2016 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 SUPERFAMILY SSF88659 106 187 6.76E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 Gene3D G3DSA:1.10.1740.10 8 117 4.6E-19 T 16-09-2016 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 Gene3D G3DSA:1.10.10.10 123 186 7.3E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 Pfam PF04542 Sigma-70 region 2 25 91 1.7E-10 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 185 3.4E-20 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 SUPERFAMILY SSF88946 4 107 1.37E-16 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28595 c36316bec44f854ef5671760aba81d90 191 PANTHER PTHR30173:SF6 1 186 1.8E-65 T 16-09-2016 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 SUPERFAMILY SSF51445 230 318 9.48E-22 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 SUPERFAMILY SSF49785 2 129 1.4E-37 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 SUPERFAMILY SSF49303 132 232 4.6E-10 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 PANTHER PTHR10066 1 321 1.5E-161 T 16-09-2016 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 Pfam PF00703 Glycosyl hydrolases family 2 131 232 6.2E-6 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 PANTHER PTHR10066:SF58 1 321 1.5E-161 T 16-09-2016 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 Gene3D G3DSA:2.60.120.260 2 119 2.1E-44 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 Gene3D G3DSA:3.20.20.80 234 317 7.1E-21 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 Gene3D G3DSA:2.60.40.320 120 232 4.0E-16 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS32965 f503cc6128c0dc83d6897d1bd0c12b0c 326 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 21 95 4.4E-12 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS25255 ad7ed3fcc260961d1fac62a99422ab21 307 PANTHER PTHR32243 29 307 1.1E-98 T 16-09-2016 Spa2297_RS25255 ad7ed3fcc260961d1fac62a99422ab21 307 PANTHER PTHR32243:SF24 29 307 1.1E-98 T 16-09-2016 Spa2297_RS25255 ad7ed3fcc260961d1fac62a99422ab21 307 Gene3D G3DSA:1.10.3720.10 32 295 4.3E-64 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25255 ad7ed3fcc260961d1fac62a99422ab21 307 SUPERFAMILY SSF161098 35 307 9.42E-71 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25255 ad7ed3fcc260961d1fac62a99422ab21 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 301 1.5E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 SUPERFAMILY SSF53850 59 593 1.86E-92 T 16-09-2016 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 PANTHER PTHR30290 1 597 4.0E-200 T 16-09-2016 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 PIRSF PIRSF002741 10 589 5.0E-58 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 Gene3D G3DSA:3.10.105.10 349 561 3.2E-34 T 16-09-2016 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 Gene3D G3DSA:3.40.190.10 244 348 2.2E-20 T 16-09-2016 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 505 4.0E-74 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 Gene3D G3DSA:3.90.76.10 74 243 6.8E-33 T 16-09-2016 Spa2297_RS23160 b96eb1aeb98f64b7f5058113495f50c4 597 PANTHER PTHR30290:SF31 1 597 4.0E-200 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Pfam PF03129 Anticodon binding domain 561 649 3.0E-18 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 235 3.5E-13 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 SUPERFAMILY SSF52954 549 654 1.27E-28 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 SUPERFAMILY SSF55681 259 546 4.59E-91 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PANTHER PTHR11451:SF5 32 657 3.2E-267 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 527 540 7.6E-52 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 348 376 7.6E-52 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 381 404 7.6E-52 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 484 512 7.6E-52 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PRINTS PR01047 Threonyl-tRNA synthetase signature 554 566 7.6E-52 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Gene3D G3DSA:3.30.980.10 66 129 3.3E-42 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Gene3D G3DSA:3.30.980.10 204 240 3.3E-42 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 SUPERFAMILY SSF55186 64 257 2.22E-53 T 16-09-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 654 32.977 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 650 1.6E-196 T 16-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 342 549 1.3E-35 T 16-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Gene3D G3DSA:3.30.54.20 132 203 1.5E-11 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Gene3D G3DSA:3.40.50.800 551 656 1.4E-31 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 Gene3D G3DSA:3.30.930.10 258 550 1.9E-103 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 PANTHER PTHR11451 32 657 3.2E-267 T 16-09-2016 Spa2297_RS05815 d84cbc5b689511e3c2ec7da0649cec97 658 SMART SM00863 179 235 3.8E-20 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS30320 f93ad63aaa4b8f4b57d2ea0fc6182041 142 Gene3D G3DSA:3.30.565.10 56 141 1.3E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30320 f93ad63aaa4b8f4b57d2ea0fc6182041 142 Pfam PF13581 Histidine kinase-like ATPase domain 31 135 1.3E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30320 f93ad63aaa4b8f4b57d2ea0fc6182041 142 SUPERFAMILY SSF55874 49 141 3.27E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 Gene3D G3DSA:3.60.15.10 18 216 7.0E-47 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 PANTHER PTHR11935:SF89 20 216 4.5E-127 T 16-09-2016 Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 SUPERFAMILY SSF56281 22 214 3.52E-42 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 SMART SM00849 32 197 2.1E-28 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 PANTHER PTHR11935 20 216 4.5E-127 T 16-09-2016 Spa2297_RS07910 1ab66a4ad1ef5a626989998c9ebfac1c 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 176 8.2E-9 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS30455 97bafca823c8ce4c40eca57537a9abde 127 SUPERFAMILY SSF46785 13 121 5.09E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30455 97bafca823c8ce4c40eca57537a9abde 127 Pfam PF03965 Penicillinase repressor 13 119 1.2E-21 T 16-09-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 Spa2297_RS30455 97bafca823c8ce4c40eca57537a9abde 127 Gene3D G3DSA:1.10.10.10 13 75 1.5E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30455 97bafca823c8ce4c40eca57537a9abde 127 PANTHER PTHR34134:SF1 1 126 1.2E-32 T 16-09-2016 Spa2297_RS30455 97bafca823c8ce4c40eca57537a9abde 127 PANTHER PTHR34134 1 126 1.2E-32 T 16-09-2016 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 27 56 1.6E-11 T 16-09-2016 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 PANTHER PTHR33711:SF1 7 257 3.0E-144 T 16-09-2016 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 Gene3D G3DSA:2.60.130.10 32 255 2.3E-69 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 Pfam PF00775 Dioxygenase 67 247 2.2E-58 T 16-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 98 126 - T 16-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 PANTHER PTHR33711 7 257 3.0E-144 T 16-09-2016 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 32 255 1.9E-103 T 16-09-2016 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 Spa2297_RS27885 173d7c09c8b7348b7b780cf82fc1bf63 257 SUPERFAMILY SSF49482 32 254 1.31E-64 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 PANTHER PTHR30108:SF2 2 215 1.5E-68 T 16-09-2016 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 Gene3D G3DSA:3.40.50.1950 3 207 1.3E-62 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 207 30.287 T 16-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 SUPERFAMILY SSF52507 4 207 1.57E-43 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 Pfam PF02441 Flavoprotein 3 148 7.6E-23 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 83 205 5.6E-33 T 16-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 Spa2297_RS18850 d1ed0e642dc607e734286cb4ad067b04 216 PANTHER PTHR30108 2 215 1.5E-68 T 16-09-2016 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 SUPERFAMILY SSF53901 8 256 4.39E-65 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 Gene3D G3DSA:3.40.47.10 267 414 6.5E-59 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 371 1.9E-33 T 16-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 Gene3D G3DSA:3.40.47.10 9 261 1.9E-61 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 251 5.5E-46 T 16-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 SMART SM00825 Beta-ketoacyl synthase 8 416 1.3E-15 T 16-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 SUPERFAMILY SSF53901 218 413 2.84E-63 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 PANTHER PTHR11712 9 411 3.4E-145 T 16-09-2016 Spa2297_RS26620 01547287a5e48c4bd32bcef6c663c555 427 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 158 174 - T 16-09-2016 IPR018201 Beta-ketoacyl synthase, active site Spa2297_RS28380 50ccbce29ad302d08f8c14e1292ff3a0 216 Gene3D G3DSA:1.10.340.30 40 148 4.3E-6 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS28380 50ccbce29ad302d08f8c14e1292ff3a0 216 SUPERFAMILY SSF48150 39 184 1.29E-12 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS13185 c93d8e9345243e864622b37074a9beca 504 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 87 246 4.4E-41 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13185 c93d8e9345243e864622b37074a9beca 504 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 371 463 3.0E-14 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS13185 c93d8e9345243e864622b37074a9beca 504 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 246 5.6E-34 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13185 c93d8e9345243e864622b37074a9beca 504 PANTHER PTHR33392:SF7 1 504 8.7E-207 T 16-09-2016 Spa2297_RS13185 c93d8e9345243e864622b37074a9beca 504 PANTHER PTHR33392 1 504 8.7E-207 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606:SF1 244 599 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606:SF1 712 1140 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606:SF1 35 171 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606 35 171 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 97 1644 0.0 T 16-09-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606 1165 1410 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606 712 1140 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 SUPERFAMILY SSF53223 795 997 7.58E-22 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 Gene3D G3DSA:3.40.50.720 1151 1223 1.3E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 Gene3D G3DSA:3.40.50.720 983 1094 1.3E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606 244 599 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PIRSF PIRSF036761 32 1651 0.0 T 16-09-2016 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 PANTHER PTHR11606:SF1 1165 1410 0.0 T 16-09-2016 Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 SUPERFAMILY SSF51735 986 1088 1.51E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12955 f1cac3cf2ff9387eed8fd0c7231aca6d 1651 SUPERFAMILY SSF51735 1126 1324 1.51E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 545 1.2E-126 T 16-09-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PIRSF PIRSF000732 1 556 2.5E-171 T 16-09-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Gene3D G3DSA:3.50.30.10 130 244 1.5E-33 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PANTHER PTHR22931:SF28 67 534 2.7E-147 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Gene3D G3DSA:3.20.20.60 250 551 1.6E-87 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 16-09-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 1.1E-17 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 1.1E-17 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 1.1E-17 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 1.1E-17 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 16-09-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 SUPERFAMILY SSF51621 245 533 2.62E-84 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 1.7E-21 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Gene3D G3DSA:1.10.274.10 28 129 4.5E-22 T 16-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 SUPERFAMILY SSF47831 30 140 1.57E-21 T 16-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 4.6E-22 T 16-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 PANTHER PTHR22931 67 534 2.7E-147 T 16-09-2016 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 SUPERFAMILY SSF52009 123 238 4.97E-30 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS05125 86da551d06a88b08e05288ceb13b22e4 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 524 2.9E-78 T 16-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spa2297_RS30300 db80d483fa3e8a94f076138f5feab7d5 57 SUPERFAMILY SSF69047 4 54 2.75E-8 T 16-09-2016 IPR008462 CsbD-like Spa2297_RS30300 db80d483fa3e8a94f076138f5feab7d5 57 Pfam PF05532 CsbD-like 6 57 2.7E-16 T 16-09-2016 IPR008462 CsbD-like Spa2297_RS30300 db80d483fa3e8a94f076138f5feab7d5 57 Gene3D G3DSA:1.10.1470.10 5 56 1.2E-10 T 16-09-2016 IPR008462 CsbD-like Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 Gene3D G3DSA:1.10.1740.10 26 86 1.1E-6 T 16-09-2016 Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 Gene3D G3DSA:1.10.10.10 96 160 6.7E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 SUPERFAMILY SSF88946 11 80 2.28E-6 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 Pfam PF04542 Sigma-70 region 2 6 73 7.1E-5 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 156 2.8E-14 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06000 4f06822f6bbe3987a71fec510db67792 168 SUPERFAMILY SSF88659 83 158 5.23E-8 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 222 6.7E-80 T 16-09-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 PANTHER PTHR10099 4 221 1.7E-109 T 16-09-2016 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 221 39.734 T 16-09-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 204 9.1E-33 T 16-09-2016 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 Gene3D G3DSA:3.40.50.880 3 222 1.6E-39 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 SUPERFAMILY SSF52317 3 221 2.15E-68 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 SMART SM01211 2 223 5.2E-122 T 16-09-2016 Spa2297_RS15795 afaf425c85a0eae5ec8dcd4f3c4311ef 226 PIRSF PIRSF001586 1 226 4.6E-83 T 16-09-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS24905 be861343a78cbf8334e4e0ec51b3908a 687 PANTHER PTHR11785:SF125 35 517 1.8E-192 T 16-09-2016 Spa2297_RS24905 be861343a78cbf8334e4e0ec51b3908a 687 Pfam PF13520 Amino acid permease 57 467 1.3E-32 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS24905 be861343a78cbf8334e4e0ec51b3908a 687 PANTHER PTHR11785 35 517 1.8E-192 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 8.9E-32 T 16-09-2016 IPR021131 Ribosomal protein L18e/L15P Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 SUPERFAMILY SSF52080 10 149 1.06E-39 T 16-09-2016 IPR021131 Ribosomal protein L18e/L15P Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 PANTHER PTHR12934 7 150 3.8E-61 T 16-09-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 2.1E-44 T 16-09-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 Gene3D G3DSA:3.100.10.10 37 150 1.3E-31 T 16-09-2016 Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 16-09-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19890 e95519a4a22156a6362a12a4b512d98c 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.78 T 16-09-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Spa2297_RS03440 4f4fecbd2e5743776b4c69a9b72b7ee9 172 SUPERFAMILY SSF55874 19 120 2.97E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03440 4f4fecbd2e5743776b4c69a9b72b7ee9 172 Pfam PF13581 Histidine kinase-like ATPase domain 4 116 9.1E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21920 dbd6f1960a3cfd835a4efcb4e6efd092 122 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 17 113 13.201 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS21920 dbd6f1960a3cfd835a4efcb4e6efd092 122 Pfam PF02467 Transcription factor WhiB 49 97 8.5E-15 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS21920 dbd6f1960a3cfd835a4efcb4e6efd092 122 PANTHER PTHR38839 14 122 4.1E-80 T 16-09-2016 Spa2297_RS21920 dbd6f1960a3cfd835a4efcb4e6efd092 122 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 107 117 - T 16-09-2016 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 Spa2297_RS21920 dbd6f1960a3cfd835a4efcb4e6efd092 122 PANTHER PTHR38839:SF2 14 122 4.1E-80 T 16-09-2016 Spa2297_RS31755 6a189a44da298359eaa4292b99a52741 269 SUPERFAMILY SSF53448 1 255 1.6E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS31755 6a189a44da298359eaa4292b99a52741 269 Gene3D G3DSA:3.90.550.10 1 254 2.1E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS31755 6a189a44da298359eaa4292b99a52741 269 PANTHER PTHR22572:SF24 2 257 1.9E-160 T 16-09-2016 Spa2297_RS31755 6a189a44da298359eaa4292b99a52741 269 PANTHER PTHR22572 2 257 1.9E-160 T 16-09-2016 Spa2297_RS03680 bbc3f715389a09baa10a4407cb6b9f0c 223 SUPERFAMILY SSF48317 21 221 3.92E-35 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03680 bbc3f715389a09baa10a4407cb6b9f0c 223 Pfam PF01569 PAP2 superfamily 103 221 2.3E-20 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03680 bbc3f715389a09baa10a4407cb6b9f0c 223 SMART SM00014 102 215 1.1E-12 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03680 bbc3f715389a09baa10a4407cb6b9f0c 223 Gene3D G3DSA:1.20.144.10 36 221 3.5E-30 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03680 bbc3f715389a09baa10a4407cb6b9f0c 223 PANTHER PTHR14969 23 222 1.6E-27 T 16-09-2016 Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 PANTHER PTHR24421 300 435 1.1E-100 T 16-09-2016 Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 PANTHER PTHR24421 55 273 1.1E-100 T 16-09-2016 Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 Pfam PF07730 Histidine kinase 207 272 5.0E-18 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 SUPERFAMILY SSF55874 316 433 5.72E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 PANTHER PTHR24421:SF26 300 435 1.1E-100 T 16-09-2016 Spa2297_RS13545 99b22c51d60920b8d52f28952fbc4fe2 435 PANTHER PTHR24421:SF26 55 273 1.1E-100 T 16-09-2016 Spa2297_RS22130 32a271ab890e067d051df639689f7c15 91 PANTHER PTHR40034:SF1 15 81 1.4E-20 T 16-09-2016 Spa2297_RS22130 32a271ab890e067d051df639689f7c15 91 Pfam PF11755 Protein of unknown function (DUF3311) 23 80 5.5E-23 T 16-09-2016 IPR021741 Protein of unknown function DUF3311 Spa2297_RS22130 32a271ab890e067d051df639689f7c15 91 PANTHER PTHR40034 15 81 1.4E-20 T 16-09-2016 Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 Gene3D G3DSA:3.40.50.720 3 219 3.0E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PANTHER PTHR24322 6 180 1.0E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.7E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.7E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.7E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PANTHER PTHR24322:SF513 6 180 1.0E-43 T 16-09-2016 Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PIRSF PIRSF000126 1 254 1.6E-65 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 SUPERFAMILY SSF51735 3 228 1.14E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.9E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.9E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.9E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.9E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.9E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20090 cb391c37ba001a29c33228069891ab5f 257 Pfam PF00106 short chain dehydrogenase 3 188 1.2E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 Gene3D G3DSA:3.40.710.10 66 323 1.1E-80 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 PANTHER PTHR21581 50 323 3.9E-65 T 16-09-2016 Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 97 108 8.9E-14 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 184 197 8.9E-14 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 168 8.9E-14 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 65 304 3.6E-41 T 16-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 SUPERFAMILY SSF56601 67 323 3.35E-58 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16900 0d54dbd34e795ceff20a6a0bbedf56cd 326 PANTHER PTHR21581:SF3 50 323 3.9E-65 T 16-09-2016 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Pfam PF04539 Sigma-70 region 3 265 341 3.2E-26 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 210 223 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 183 407 4.0E-38 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PANTHER PTHR30603:SF0 74 419 1.5E-163 T 16-09-2016 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Pfam PF00140 Sigma-70 factor, region 1.2 121 154 2.1E-15 T 16-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Gene3D G3DSA:1.10.10.10 348 419 3.4E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Pfam PF04542 Sigma-70 region 2 186 255 1.8E-23 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 SUPERFAMILY SSF88659 259 332 2.75E-18 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PRINTS PR00046 Major sigma-70 factor signature 394 405 8.8E-30 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PRINTS PR00046 Major sigma-70 factor signature 379 394 8.8E-30 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PRINTS PR00046 Major sigma-70 factor signature 234 242 8.8E-30 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PRINTS PR00046 Major sigma-70 factor signature 210 223 8.8E-30 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PRINTS PR00046 Major sigma-70 factor signature 358 370 8.8E-30 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Pfam PF04545 Sigma-70, region 4 354 407 5.7E-20 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 PANTHER PTHR30603 74 419 1.5E-163 T 16-09-2016 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Gene3D G3DSA:1.10.601.10 103 255 1.4E-62 T 16-09-2016 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 SUPERFAMILY SSF88946 118 256 6.28E-51 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 Gene3D G3DSA:1.10.10.10 259 310 4.1E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 379 405 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS10410 2a52e19f8f509efe398c16a432e0f6ec 419 SUPERFAMILY SSF88659 317 417 2.06E-28 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 PANTHER PTHR24220:SF438 5 271 1.0E-160 T 16-09-2016 Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 SMART SM00382 28 217 2.3E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 Gene3D G3DSA:3.40.50.300 4 237 8.9E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 Pfam PF00005 ABC transporter 21 167 2.2E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 SUPERFAMILY SSF52540 4 229 8.26E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07055 29b79055e358da24519bd33047aac408 277 PANTHER PTHR24220 5 271 1.0E-160 T 16-09-2016 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 Pfam PF00072 Response regulator receiver domain 5 114 5.5E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 PANTHER PTHR26402:SF50 3 224 2.6E-110 T 16-09-2016 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 SMART SM00448 3 113 1.1E-44 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 SUPERFAMILY SSF52172 4 176 4.13E-43 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 PANTHER PTHR26402 3 224 2.6E-110 T 16-09-2016 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 Gene3D G3DSA:3.40.50.2300 2 123 1.3E-40 T 16-09-2016 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 8.5E-26 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 SMART SM00862 146 222 3.2E-22 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS13015 25632e6cab98ca265d911c0b58e50be8 225 Gene3D G3DSA:1.10.10.10 124 222 7.4E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 3.8E-168 T 16-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Gene3D G3DSA:1.10.300.10 101 194 3.2E-34 T 16-09-2016 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 4.3E-179 T 16-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 202.058 T 16-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Gene3D G3DSA:3.40.440.10 4 93 1.1E-71 T 16-09-2016 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Gene3D G3DSA:3.40.440.10 195 264 1.1E-71 T 16-09-2016 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 16-09-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 16-09-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 SMART SM00788 3 422 8.4E-290 T 16-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 Gene3D G3DSA:3.90.170.10 266 422 1.4E-69 T 16-09-2016 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 PANTHER PTHR11846 5 426 1.6E-246 T 16-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 Spa2297_RS17675 8d362288f958817587463aa151e1bd0e 427 SUPERFAMILY SSF52540 3 425 2.66E-175 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 64 4.2E-16 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 Gene3D G3DSA:3.40.50.2300 70 186 6.2E-35 T 16-09-2016 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 Gene3D G3DSA:3.40.50.2300 187 347 2.5E-40 T 16-09-2016 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 PANTHER PTHR30146 16 347 3.9E-158 T 16-09-2016 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 PANTHER PTHR30146:SF2 16 347 3.9E-158 T 16-09-2016 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 20 38 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 SUPERFAMILY SSF47413 17 75 2.25E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 SUPERFAMILY SSF53822 75 344 2.52E-52 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 Pfam PF13377 Periplasmic binding protein-like domain 184 347 4.1E-30 T 16-09-2016 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 SMART SM00354 17 87 4.2E-22 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS32055 fe31b939e50ac38a9b44232a036f1178 347 Gene3D G3DSA:1.10.260.40 18 69 1.4E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423 392 408 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 Gene3D G3DSA:3.30.565.10 491 635 2.0E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 Pfam PF00672 HAMP domain 324 409 1.6E-18 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423 433 662 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423 337 375 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423 4 9 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 529 635 3.2E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423:SF508 392 408 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 Pfam PF08376 Nitrate and nitrite sensing 67 302 3.2E-31 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 SUPERFAMILY SSF55874 493 634 1.96E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 SMART SM00387 525 637 8.0E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423:SF508 433 662 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423:SF508 337 375 1.1E-111 T 16-09-2016 Spa2297_RS25590 46e0cad1d87dd23641774e7ac5d6cbf0 790 PANTHER PTHR24423:SF508 4 9 1.1E-111 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 PANTHER PTHR24221:SF161 1050 1180 2.3E-175 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SMART SM00382 359 545 2.8E-19 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SMART SM00382 961 1147 1.6E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 PANTHER PTHR24221 1050 1180 2.3E-175 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SUPERFAMILY SSF90123 607 917 1.7E-38 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 ProSitePatterns PS00211 ABC transporters family signature. 1073 1087 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SUPERFAMILY SSF52540 326 550 2.51E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Pfam PF00005 ABC transporter 351 499 1.9E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Pfam PF00005 ABC transporter 953 1100 4.1E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 605 1131 4.4E-197 T 16-09-2016 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Gene3D G3DSA:1.20.1560.10 607 921 4.9E-30 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Gene3D G3DSA:1.20.1560.10 6 320 1.7E-49 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Gene3D G3DSA:3.40.50.300 332 542 1.2E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Gene3D G3DSA:3.40.50.300 937 1162 4.5E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SUPERFAMILY SSF90123 2 322 1.83E-57 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 PANTHER PTHR24221:SF161 7 447 2.3E-175 T 16-09-2016 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 SUPERFAMILY SSF52540 930 1167 2.62E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 541 3.2E-220 T 16-09-2016 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 Pfam PF00664 ABC transporter transmembrane region 21 283 3.5E-30 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS16285 082c1f0e5c42b65da2c88eead418a629 1181 PANTHER PTHR24221 7 447 2.3E-175 T 16-09-2016 Spa2297_RS31070 bd08e4197a1cbc376a7c424d206045eb 353 PANTHER PTHR30472:SF31 5 353 1.8E-160 T 16-09-2016 Spa2297_RS31070 bd08e4197a1cbc376a7c424d206045eb 353 PANTHER PTHR30472 5 353 1.8E-160 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31070 bd08e4197a1cbc376a7c424d206045eb 353 Pfam PF01032 FecCD transport family 32 347 7.4E-81 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31070 bd08e4197a1cbc376a7c424d206045eb 353 Gene3D G3DSA:1.10.3470.10 20 349 9.6E-91 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS31070 bd08e4197a1cbc376a7c424d206045eb 353 SUPERFAMILY SSF81345 19 347 4.97E-71 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 SUPERFAMILY SSF140490 321 419 1.83E-16 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 SUPERFAMILY SSF142984 242 316 4.84E-9 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 PANTHER PTHR11780:SF7 41 449 0.0 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 217 2.1E-31 T 16-09-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 SUPERFAMILY SSF142019 28 239 1.31E-33 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 SUPERFAMILY SSF54862 448 508 2.01E-7 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 PANTHER PTHR11780 41 449 0.0 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 Gene3D G3DSA:3.30.70.20 448 510 8.9E-12 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 330 409 3.5E-15 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 Pfam PF10531 SLBB domain 242 273 1.5E-6 T 16-09-2016 IPR019554 Soluble ligand binding domain Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 Pfam PF13459 4Fe-4S single cluster domain 449 507 2.8E-13 T 16-09-2016 Spa2297_RS10855 d84bf8ce8e50aa13701dcbfcd101930b 536 SMART SM00928 325 369 4.9E-5 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 PANTHER PTHR12286:SF6 1 406 6.1E-114 T 16-09-2016 Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 Gene3D G3DSA:3.40.50.720 1 169 4.1E-21 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 142 1.5E-21 T 16-09-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 SUPERFAMILY SSF51735 1 169 1.51E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 146 398 1.5E-18 T 16-09-2016 IPR032095 Saccharopine dehydrogenase, C-terminal Spa2297_RS30820 a92045c96f2982868bd541712a47d9ee 407 PANTHER PTHR12286 1 406 6.1E-114 T 16-09-2016 Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 Pfam PF13280 WYL domain 140 324 5.5E-41 T 16-09-2016 IPR026881 WYL domain Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 PANTHER PTHR30595:SF4 1 318 5.3E-159 T 16-09-2016 Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 Gene3D G3DSA:1.10.10.10 3 63 8.5E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 PANTHER PTHR30595 1 318 5.3E-159 T 16-09-2016 Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 SUPERFAMILY SSF46785 3 59 1.18E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09030 fbc526068a1c8a9d3b33bddaa3ebaae4 335 Pfam PF08279 HTH domain 5 60 6.4E-16 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 SMART SM01240 14 373 5.0E-27 T 16-09-2016 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 2.3E-42 T 16-09-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 Gene3D G3DSA:3.20.20.70 13 367 1.4E-74 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 SUPERFAMILY SSF51412 12 77 6.72E-69 T 16-09-2016 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 SUPERFAMILY SSF51412 113 369 6.72E-69 T 16-09-2016 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 PANTHER PTHR11911 223 296 2.8E-13 T 16-09-2016 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 PANTHER PTHR11911:SF6 223 296 2.8E-13 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20125 9d93d88e1b0461183dcd33acb52ced37 374 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 6.7E-199 T 16-09-2016 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SUPERFAMILY SSF50952 35 362 1.29E-24 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SUPERFAMILY SSF50952 397 477 1.29E-24 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Gene3D G3DSA:2.120.10.30 12 498 8.4E-105 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 PANTHER PTHR19328 62 492 1.6E-84 T 16-09-2016 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Pfam PF00652 Ricin-type beta-trefoil lectin domain 826 945 4.9E-29 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SUPERFAMILY SSF49299 496 582 2.75E-22 T 16-09-2016 IPR000601 PKD domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SUPERFAMILY SSF50370 830 947 1.28E-39 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SMART SM00458 824 948 3.6E-34 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Gene3D G3DSA:2.60.120.260 686 816 1.1E-37 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SMART SM00089 499 582 2.8E-20 T 16-09-2016 IPR022409 PKD/Chitinase domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SMART SM00606 686 817 4.5E-45 T 16-09-2016 IPR006584 Cellulose binding, type IV GO:0030246 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Pfam PF00801 PKD domain 511 571 1.1E-9 T 16-09-2016 IPR000601 PKD domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Pfam PF03422 Carbohydrate binding module (family 6) 694 816 5.9E-32 T 16-09-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Gene3D G3DSA:2.80.10.50 830 947 1.5E-40 T 16-09-2016 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Pfam PF07995 Glucose / Sorbosone dehydrogenase 62 336 8.3E-35 T 16-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 Gene3D G3DSA:2.60.40.670 499 582 2.0E-23 T 16-09-2016 IPR000601 PKD domain Spa2297_RS10355 b8dbf6ac3459272e1d4c176c93c17e5c 948 SUPERFAMILY SSF49785 688 816 1.2E-24 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS25675 9035091b448ac7136454c41ccaff70d7 441 Gene3D G3DSA:3.40.630.10 4 162 1.1E-12 T 16-09-2016 Spa2297_RS25675 9035091b448ac7136454c41ccaff70d7 441 Pfam PF00246 Zinc carboxypeptidase 10 100 1.3E-8 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS25675 9035091b448ac7136454c41ccaff70d7 441 SUPERFAMILY SSF53187 221 323 9.26E-19 T 16-09-2016 Spa2297_RS25675 9035091b448ac7136454c41ccaff70d7 441 SUPERFAMILY SSF53187 9 192 9.26E-19 T 16-09-2016 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PIRSF PIRSF000114 2 335 5.1E-97 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 Gene3D G3DSA:3.40.50.720 3 186 4.1E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 Gene3D G3DSA:1.10.1040.10 187 329 7.2E-54 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 1.8E-43 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 PANTHER PTHR11728 3 335 5.2E-142 T 16-09-2016 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 SUPERFAMILY SSF48179 182 334 2.61E-54 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 SUPERFAMILY SSF51735 4 183 4.57E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 163 7.1E-50 T 16-09-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 321 2.7E-48 T 16-09-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 38.319 T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS23580 b4d0df7e0aa5b6d4ad9a0a1602f200c3 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 16-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 SUPERFAMILY SSF55781 77 263 3.2E-41 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 Pfam PF01614 Bacterial transcriptional regulator 139 259 4.6E-21 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 SMART SM00346 19 109 4.4E-9 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 Pfam PF09339 IclR helix-turn-helix domain 21 72 1.0E-12 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 PANTHER PTHR30136 13 274 6.3E-107 T 16-09-2016 Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 Gene3D G3DSA:3.30.450.40 98 264 2.7E-43 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 Gene3D G3DSA:1.10.10.10 13 87 1.7E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 PANTHER PTHR30136:SF14 13 274 6.3E-107 T 16-09-2016 Spa2297_RS30735 8e2e93fb5ccf651eeb8c80e1aba3ed2f 278 SUPERFAMILY SSF46785 20 91 4.61E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 13 365 1.8E-86 T 16-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 PANTHER PTHR11933 1 370 5.5E-159 T 16-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 SUPERFAMILY SSF52402 12 255 1.68E-46 T 16-09-2016 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 Pfam PF03054 tRNA methyl transferase 12 365 2.6E-119 T 16-09-2016 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 Gene3D G3DSA:2.40.30.10 291 370 1.5E-18 T 16-09-2016 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 366 36.272 T 16-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 Gene3D G3DSA:3.40.50.620 8 222 7.8E-76 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 PANTHER PTHR11933:SF10 1 370 5.5E-159 T 16-09-2016 Spa2297_RS23220 07797d646a2dba9d82a16e8397d8e4fb 376 Gene3D G3DSA:2.30.30.280 225 286 8.2E-16 T 16-09-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PANTHER PTHR10422 20 568 5.7E-299 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 44 486 4.0E-145 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 108 132 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 323 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 412 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 163 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 365 383 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 34 59 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 351 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 443 464 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 81 104 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 262 283 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PRINTS PR01165 Cytochrome c oxidase subunit I signature 241 262 4.0E-102 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 Gene3D G3DSA:1.20.210.10 27 554 2.9E-193 T 16-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 264 318 - T 16-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 PANTHER PTHR10422:SF6 20 568 5.7E-299 T 16-09-2016 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 SUPERFAMILY SSF81442 31 542 6.28E-175 T 16-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS08885 2215ca3185a5d34f5c7698ef8d6a7cfa 578 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 35 539 1.8E-212 T 16-09-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 SUPERFAMILY SSF48208 319 475 8.5E-18 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 SUPERFAMILY SSF48208 514 776 8.5E-18 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 Gene3D G3DSA:1.20.1050.60 403 495 7.7E-22 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143:SF22 49 262 3.6E-102 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143:SF22 510 798 3.6E-102 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 Pfam PF07971 Glycosyl hydrolase family 92 293 794 9.4E-147 T 16-09-2016 IPR012939 Glycosyl hydrolase family 92 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 Gene3D G3DSA:2.70.98.10 45 377 2.4E-88 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 Gene3D G3DSA:1.20.1610.10 509 665 2.1E-40 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143 279 492 3.6E-102 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143 49 262 3.6E-102 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143 510 798 3.6E-102 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 42 798 3.6E-150 T 16-09-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 Gene3D G3DSA:3.30.2080.10 666 805 1.4E-48 T 16-09-2016 Spa2297_RS01770 b72970b5d8749d55d5caa55cc2f4281b 811 PANTHER PTHR12143:SF22 279 492 3.6E-102 T 16-09-2016 Spa2297_RS31490 f3450a9a89b532ef213d322c64be3013 162 SUPERFAMILY SSF54197 17 129 9.14E-16 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS31490 f3450a9a89b532ef213d322c64be3013 162 PANTHER PTHR23089:SF13 17 123 7.5E-14 T 16-09-2016 Spa2297_RS31490 f3450a9a89b532ef213d322c64be3013 162 Gene3D G3DSA:3.30.428.10 16 130 1.8E-19 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS31490 f3450a9a89b532ef213d322c64be3013 162 PANTHER PTHR23089 17 123 7.5E-14 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 111 195 2.7E-17 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 SUPERFAMILY SSF110221 785 941 5.62E-50 T 16-09-2016 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Gene3D G3DSA:2.80.10.50 786 941 9.5E-44 T 16-09-2016 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Gene3D G3DSA:2.80.10.50 626 776 1.3E-37 T 16-09-2016 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 PANTHER PTHR10066 1 618 3.3E-223 T 16-09-2016 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 SUPERFAMILY SSF51445 321 610 5.06E-56 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 PANTHER PTHR10066:SF44 1 618 3.3E-223 T 16-09-2016 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 SUPERFAMILY SSF49303 239 324 3.45E-13 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 SUPERFAMILY SSF49785 48 228 4.39E-49 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 794 936 5.0E-50 T 16-09-2016 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 635 773 1.3E-42 T 16-09-2016 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 SUPERFAMILY SSF110221 621 776 8.37E-46 T 16-09-2016 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Gene3D G3DSA:3.20.20.80 323 612 2.4E-45 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Gene3D G3DSA:2.60.40.320 219 322 3.1E-18 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Gene3D G3DSA:2.60.120.260 47 218 1.1E-57 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00695 12588f35e2ed3f603f9b04eec6b4187f 942 Pfam PF00703 Glycosyl hydrolases family 2 234 324 1.3E-9 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 Pfam PF00664 ABC transporter transmembrane region 19 288 7.6E-45 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 Gene3D G3DSA:3.40.50.300 333 564 2.3E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 SMART SM00382 360 546 7.6E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 PANTHER PTHR24221 3 575 6.7E-241 T 16-09-2016 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 SUPERFAMILY SSF90123 6 315 5.76E-74 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 Pfam PF00005 ABC transporter 351 498 1.6E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 PANTHER PTHR24221:SF190 3 575 6.7E-241 T 16-09-2016 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 Gene3D G3DSA:1.20.1560.10 6 320 8.9E-66 T 16-09-2016 Spa2297_RS10390 d4c445366c83d8600c3303c156782fe7 577 SUPERFAMILY SSF52540 328 570 4.26E-80 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 378 388 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Gene3D G3DSA:3.40.640.10 48 122 2.2E-89 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Gene3D G3DSA:3.40.640.10 154 327 2.2E-89 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 SUPERFAMILY SSF53383 10 123 1.41E-146 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 SUPERFAMILY SSF53383 155 478 1.41E-146 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 PIRSF PIRSF000412 2 480 1.3E-160 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 18 476 44.732 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Pfam PF00464 Serine hydroxymethyltransferase 21 122 5.8E-26 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Pfam PF00464 Serine hydroxymethyltransferase 155 429 5.8E-93 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 PANTHER PTHR11680 161 480 1.7E-171 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 PANTHER PTHR11680:SF0 161 480 1.7E-171 T 16-09-2016 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 Gene3D G3DSA:3.90.1150.10 328 476 5.4E-48 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 PANTHER PTHR11680 17 119 1.7E-171 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 PANTHER PTHR11680:SF0 17 119 1.7E-171 T 16-09-2016 Spa2297_RS20420 efbea90b33f5ca45b85e85e69ed1683e 481 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 267 283 - T 16-09-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PRINTS PR01576 Peptide deformylase signature 124 135 1.7E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PRINTS PR01576 Peptide deformylase signature 155 184 1.7E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PRINTS PR01576 Peptide deformylase signature 136 154 1.7E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PRINTS PR01576 Peptide deformylase signature 55 84 1.7E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 Pfam PF01327 Polypeptide deformylase 25 185 5.7E-39 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PIRSF PIRSF004749 6 208 3.6E-52 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 Hamap MF_00163 Peptide deformylase [def]. 22 196 25.843 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 PANTHER PTHR10458 11 187 8.2E-56 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 Gene3D G3DSA:3.90.45.10 24 191 6.6E-51 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS29180 2ef7b42304d4607ed4dc146855285684 218 SUPERFAMILY SSF56420 23 186 3.79E-47 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 Pfam PF00476 DNA polymerase family A 241 539 3.5E-27 T 16-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 SUPERFAMILY SSF56672 156 435 1.67E-61 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 SUPERFAMILY SSF56672 465 562 1.67E-61 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PRINTS PR00868 DNA-polymerase family A (pol I) signature 477 493 1.8E-6 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PRINTS PR00868 DNA-polymerase family A (pol I) signature 325 348 1.8E-6 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PRINTS PR00868 DNA-polymerase family A (pol I) signature 505 518 1.8E-6 T 16-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 SMART SM00482 311 522 2.1E-11 T 16-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 Gene3D G3DSA:3.30.70.370 485 560 6.2E-12 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 Gene3D G3DSA:3.30.70.370 294 333 6.2E-12 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PANTHER PTHR10133 223 438 2.3E-57 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PANTHER PTHR10133 466 563 2.3E-57 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 PANTHER PTHR10133 123 134 2.3E-57 T 16-09-2016 Spa2297_RS18035 32736f6338c6cbb2ea4bec43e5664ffb 563 Gene3D G3DSA:1.10.150.20 334 484 5.9E-20 T 16-09-2016 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 SUPERFAMILY SSF50129 1 150 8.18E-30 T 16-09-2016 IPR011032 GroES-like Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 Pfam PF00107 Zinc-binding dehydrogenase 157 238 7.5E-15 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 16-09-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 SUPERFAMILY SSF51735 118 237 3.35E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 SMART SM00829 12 301 2.4E-20 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 Gene3D G3DSA:3.40.50.720 152 237 9.1E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 1.1E-7 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 PANTHER PTHR11695 16 304 2.6E-115 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 Gene3D G3DSA:3.90.180.10 1 151 5.7E-37 T 16-09-2016 IPR011032 GroES-like Spa2297_RS02770 7297925cc015f0f21f59454e4ff54f55 307 PANTHER PTHR11695:SF533 16 304 2.6E-115 T 16-09-2016 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 PIRSF PIRSF005963 3 317 6.1E-120 T 16-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 SMART SM00729 72 286 3.5E-15 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 PANTHER PTHR10949 10 312 5.6E-137 T 16-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 311 3.3E-96 T 16-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 SUPERFAMILY SSF102114 36 305 3.01E-60 T 16-09-2016 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 61 5.9E-7 T 16-09-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 Pfam PF04055 Radical SAM superfamily 82 240 2.1E-12 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 Gene3D G3DSA:3.20.20.70 39 308 1.2E-63 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS09075 66595e80909ee86a0c8341493c73e4cd 317 Hamap MF_00206 Lipoyl synthase [lipA]. 1 313 134.408 T 16-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 Gene3D G3DSA:3.90.950.10 1 198 1.9E-80 T 16-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 PANTHER PTHR11067 1 198 6.7E-73 T 16-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 PANTHER PTHR11067:SF9 1 198 6.7E-73 T 16-09-2016 Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 SUPERFAMILY SSF52972 1 196 5.49E-66 T 16-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 46.732 T 16-09-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 Pfam PF01725 Ham1 family 4 192 2.4E-53 T 16-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 Spa2297_RS12410 268f7edba4d53cd38025b792b2464bcc 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 9.0E-52 T 16-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Gene3D G3DSA:3.40.50.300 3 90 2.1E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Gene3D G3DSA:3.40.50.300 129 272 2.1E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Gene3D G3DSA:3.40.50.300 348 525 5.5E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 SMART SM00382 356 528 2.3E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 SMART SM00382 29 236 3.3E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 SUPERFAMILY SSF52540 15 235 9.35E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Pfam PF00005 ABC transporter 21 191 7.5E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Pfam PF00005 ABC transporter 349 475 5.2E-14 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 PANTHER PTHR19211 16 524 2.8E-103 T 16-09-2016 Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 Gene3D G3DSA:3.40.50.300 99 123 4.5E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27120 50dada0cc073573a679c2f67620c1c80 539 SUPERFAMILY SSF52540 348 525 1.64E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01475 6eff22a8ecd52bccdce26c949970b376 121 Gene3D G3DSA:1.10.530.10 25 120 3.1E-36 T 16-09-2016 Spa2297_RS01475 6eff22a8ecd52bccdce26c949970b376 121 Pfam PF06737 Transglycosylase-like domain 48 121 6.0E-34 T 16-09-2016 IPR010618 Transglycosylase-like Spa2297_RS01475 6eff22a8ecd52bccdce26c949970b376 121 SUPERFAMILY SSF53955 48 120 1.9E-30 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 PANTHER PTHR10584 19 354 9.0E-116 T 16-09-2016 Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 PANTHER PTHR10584:SF157 19 354 9.0E-116 T 16-09-2016 Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 274 287 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 Gene3D G3DSA:3.40.1190.20 37 334 7.5E-56 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 Pfam PF00294 pfkB family carbohydrate kinase 65 321 4.6E-33 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS10705 2a65b3b7034b2e45c0cccfa14d722ecb 377 SUPERFAMILY SSF53613 36 329 6.24E-50 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PANTHER PTHR10381 1 202 2.6E-95 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 37.372 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PRINTS PR00127 Clp protease catalytic subunit P signature 29 44 4.1E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PRINTS PR00127 Clp protease catalytic subunit P signature 69 89 4.1E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PRINTS PR00127 Clp protease catalytic subunit P signature 100 117 4.1E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PRINTS PR00127 Clp protease catalytic subunit P signature 121 140 4.1E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 4.1E-41 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 Pfam PF00574 Clp protease 30 202 5.3E-70 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 SUPERFAMILY SSF52096 30 202 3.62E-60 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 Gene3D G3DSA:3.90.226.10 29 202 1.1E-68 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 122 135 - T 16-09-2016 IPR033135 ClpP, histidine active site Spa2297_RS02280 50d3b7d61aabc3d25a96f82e12056435 217 PANTHER PTHR10381:SF22 1 202 2.6E-95 T 16-09-2016 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 449 574 7.7E-24 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 131 178 4.6E-11 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 285 314 4.6E-11 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 SUPERFAMILY SSF56003 157 707 5.63E-156 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 PANTHER PTHR11908:SF71 15 714 0.0 T 16-09-2016 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.90.1170.50 14 130 2.2E-36 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 358 447 1.3E-57 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 575 708 1.3E-57 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Gene3D G3DSA:3.30.365.10 179 281 5.0E-34 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 SUPERFAMILY SSF54665 14 152 6.8E-37 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 562 647 4.4E-20 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 165 535 3.8E-89 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 142 7.4E-22 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 PANTHER PTHR11908 15 714 0.0 T 16-09-2016 Spa2297_RS03810 801ef6f1872fefdfc6d323d068593ec5 723 SMART SM01008 30 142 1.2E-37 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS12485 a30e9ed900b647d3dcba9a6541271c69 195 PANTHER PTHR11080:SF2 1 188 2.2E-50 T 16-09-2016 Spa2297_RS12485 a30e9ed900b647d3dcba9a6541271c69 195 PANTHER PTHR11080 1 188 2.2E-50 T 16-09-2016 Spa2297_RS12485 a30e9ed900b647d3dcba9a6541271c69 195 Gene3D G3DSA:3.40.50.850 1 188 7.4E-59 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS12485 a30e9ed900b647d3dcba9a6541271c69 195 SUPERFAMILY SSF52499 2 188 1.44E-51 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS12485 a30e9ed900b647d3dcba9a6541271c69 195 Pfam PF00857 Isochorismatase family 4 188 7.0E-33 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 PANTHER PTHR11699 9 484 1.1E-298 T 16-09-2016 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 Gene3D G3DSA:3.40.309.10 265 447 3.8E-53 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 Gene3D G3DSA:3.40.605.10 13 264 1.9E-72 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 Pfam PF00171 Aldehyde dehydrogenase family 18 473 2.9E-143 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 PANTHER PTHR11699:SF167 9 484 1.1E-298 T 16-09-2016 Spa2297_RS01560 1678e8b8b0ae3d7b02d0635960ebca6a 484 SUPERFAMILY SSF53720 12 476 5.11E-131 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 SUPERFAMILY SSF51445 18 713 9.39E-117 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:3.30.1590.10 108 223 8.4E-38 T 16-09-2016 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 18 802 1.4E-269 T 16-09-2016 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 SMART SM00642 25 709 8.0E-7 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357:SF166 624 674 1.6E-137 T 16-09-2016 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357 191 346 1.6E-137 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357:SF166 32 139 1.6E-137 T 16-09-2016 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357:SF166 694 777 1.6E-137 T 16-09-2016 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357:SF166 191 346 1.6E-137 T 16-09-2016 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:1.10.10.470 536 615 2.8E-19 T 16-09-2016 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:3.20.20.80 18 107 5.5E-68 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:3.20.20.80 496 535 5.5E-68 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:3.20.20.80 628 746 5.5E-68 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Gene3D G3DSA:3.20.20.80 239 311 5.5E-68 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357 32 139 1.6E-137 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357 694 777 1.6E-137 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 Pfam PF00128 Alpha amylase, catalytic domain 40 250 3.2E-14 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25680 ddfd67b7005a67aa53bd73a1808df851 811 PANTHER PTHR10357 624 674 1.6E-137 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 SUPERFAMILY SSF110921 470 571 9.55E-35 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 12 573 54.987 T 16-09-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 11 573 6.0E-253 T 16-09-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 SUPERFAMILY SSF51569 26 337 6.41E-94 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 SUPERFAMILY SSF89000 405 454 1.61E-15 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 PANTHER PTHR10277 2 353 5.5E-267 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 PANTHER PTHR10277 374 573 5.5E-267 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 PANTHER PTHR10277:SF28 374 573 5.5E-267 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 44 60 - T 16-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 16-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 PANTHER PTHR10277:SF28 2 353 5.5E-267 T 16-09-2016 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 Pfam PF08502 LeuA allosteric (dimerisation) domain 439 571 1.9E-35 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 Pfam PF00682 HMGL-like 37 318 9.9E-74 T 16-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 Gene3D G3DSA:3.20.20.70 15 410 2.6E-141 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS10645 52b7d1a8d7abff63e7e6fb7c20e7e0bb 573 SMART SM00917 439 572 4.7E-38 T 16-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Pfam PF08448 PAS fold 34 145 3.6E-7 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 SMART SM00388 149 217 4.1E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 SUPERFAMILY SSF55785 34 111 1.29E-9 T 16-09-2016 IPR000014 PAS domain Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Pfam PF00512 His Kinase A (phospho-acceptor) domain 151 217 2.0E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 371 2.8E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 2.8E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 2.8E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 2.8E-17 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 SMART SM00387 262 374 1.2E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Gene3D G3DSA:3.30.450.20 34 87 4.7E-11 T 16-09-2016 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 372 1.5E-25 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 SUPERFAMILY SSF55874 207 373 4.45E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 PANTHER PTHR24423 34 375 1.6E-78 T 16-09-2016 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Gene3D G3DSA:1.10.287.130 141 202 1.4E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 SUPERFAMILY SSF47384 136 218 3.14E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS06150 deabd680f4816bbf72f2c884faea6a4a 379 Gene3D G3DSA:3.30.565.10 203 373 1.7E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF56059 677 951 2.12E-89 T 16-09-2016 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 13.032 T 16-09-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Pfam PF02142 MGS-like domain 975 1065 2.6E-20 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.30.470.20 749 952 1.7E-61 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.30.470.20 206 405 7.8E-78 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SMART SM01096 426 547 8.2E-63 T 16-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.40.50.20 539 665 7.1E-56 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.40.50.20 3 108 1.8E-42 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:1.10.1030.10 406 538 8.6E-46 T 16-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF56059 128 406 9.9E-101 T 16-09-2016 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF48108 401 554 5.62E-47 T 16-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PANTHER PTHR11405 1 1092 0.0 T 16-09-2016 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF52335 960 1094 4.84E-34 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 2.3E-63 T 16-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 16-09-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 431 547 3.0E-37 T 16-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 6.1E-66 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 677 879 5.1E-33 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.40.50.1380 957 1094 7.4E-40 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF52440 2 127 7.34E-47 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 PANTHER PTHR11405:SF5 1 1092 0.0 T 16-09-2016 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SUPERFAMILY SSF52440 558 678 1.31E-42 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.30.1490.20 690 748 3.8E-25 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 Gene3D G3DSA:3.30.1490.20 149 205 5.3E-19 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS05585 cb5274bdb0427e7ee2433fdeae2f9067 1102 SMART SM00851 974 1065 4.9E-27 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PANTHER PTHR11712 1 404 1.9E-107 T 16-09-2016 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 295 322 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 353 364 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 161 176 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 144 160 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 97 108 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 344 353 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 197 219 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 278 289 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00359 B-class P450 signature 323 338 8.9E-54 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 Gene3D G3DSA:1.10.630.10 16 404 2.7E-123 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 Pfam PF00067 Cytochrome P450 48 373 3.9E-27 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 SUPERFAMILY SSF48264 18 404 1.44E-97 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00385 P450 superfamily signature 243 260 5.3E-8 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00385 P450 superfamily signature 278 289 5.3E-8 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00385 P450 superfamily signature 353 364 5.3E-8 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 PRINTS PR00385 P450 superfamily signature 344 353 5.3E-8 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29865 d6c0a29e6cd13ae851f5b87be2afbb34 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 ProSitePatterns PS00216 Sugar transport proteins signature 1. 335 352 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 Pfam PF00083 Sugar (and other) transporter 72 468 1.2E-49 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 PANTHER PTHR24064 50 468 1.2E-90 T 16-09-2016 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 Gene3D G3DSA:1.20.1250.20 279 466 1.5E-24 T 16-09-2016 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 Gene3D G3DSA:1.20.1250.20 40 218 3.8E-34 T 16-09-2016 Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 SUPERFAMILY SSF103473 27 468 1.7E-88 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS11995 5e1cb8c7a4d2c49ab3016daafc19d6ed 470 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS27585 cd93998a338e91235d3edf9e537bc9a5 548 SUPERFAMILY SSF110997 101 172 7.19E-8 T 16-09-2016 IPR007730 Sporulation-related domain GO:0042834 Spa2297_RS27585 cd93998a338e91235d3edf9e537bc9a5 548 Pfam PF05036 Sporulation related domain 101 172 4.5E-11 T 16-09-2016 IPR007730 Sporulation-related domain GO:0042834 Spa2297_RS27585 cd93998a338e91235d3edf9e537bc9a5 548 PANTHER PTHR11219 460 535 4.6E-16 T 16-09-2016 Spa2297_RS27585 cd93998a338e91235d3edf9e537bc9a5 548 Pfam PF09992 Phosphodiester glycosidase 353 541 2.9E-30 T 16-09-2016 IPR018711 Phosphodiester glycosidase Spa2297_RS27585 cd93998a338e91235d3edf9e537bc9a5 548 Gene3D G3DSA:3.30.70.1070 101 171 1.4E-10 T 16-09-2016 IPR007730 Sporulation-related domain GO:0042834 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 PANTHER PTHR11138 1 306 6.3E-101 T 16-09-2016 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 9.6E-25 T 16-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 Pfam PF00551 Formyl transferase 2 177 1.5E-32 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 Gene3D G3DSA:3.10.25.10 208 309 9.8E-33 T 16-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 SUPERFAMILY SSF53328 1 206 1.7E-56 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 301 4.8E-66 T 16-09-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 32.994 T 16-09-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 SUPERFAMILY SSF50486 205 308 1.26E-29 T 16-09-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 Spa2297_RS05535 21f87c82b18ebc0df6ef56db3579a157 310 Gene3D G3DSA:3.40.50.170 1 206 1.1E-58 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PANTHER PTHR24322:SF242 157 193 4.8E-53 T 16-09-2016 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PANTHER PTHR24322:SF242 16 141 4.8E-53 T 16-09-2016 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 189 0.0076 T 16-09-2016 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.0E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.0E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.0E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 248 8.3E-65 T 16-09-2016 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PANTHER PTHR24322 16 141 4.8E-53 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PANTHER PTHR24322 157 193 4.8E-53 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 Gene3D G3DSA:3.40.50.720 6 248 7.8E-82 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 SUPERFAMILY SSF51735 11 249 1.68E-77 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15340 91a905083a0cf44d060a5b8567f58c9f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.6E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29600 1d80066a5809c4cc232cbd7c4ed475b3 226 SUPERFAMILY SSF161098 26 208 4.19E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS29600 1d80066a5809c4cc232cbd7c4ed475b3 226 PANTHER PTHR30151:SF23 22 226 4.2E-54 T 16-09-2016 Spa2297_RS29600 1d80066a5809c4cc232cbd7c4ed475b3 226 PANTHER PTHR30151 22 226 4.2E-54 T 16-09-2016 Spa2297_RS29600 1d80066a5809c4cc232cbd7c4ed475b3 226 Gene3D G3DSA:1.10.3720.10 21 208 1.4E-27 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS29600 1d80066a5809c4cc232cbd7c4ed475b3 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 50 222 7.8E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.2E-48 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 222 6.9E-21 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 SUPERFAMILY SSF47203 232 382 5.96E-51 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 PANTHER PTHR10909 5 382 8.1E-150 T 16-09-2016 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Gene3D G3DSA:2.40.110.10 121 225 4.8E-35 T 16-09-2016 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Gene3D G3DSA:1.10.540.10 1 119 1.2E-41 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Gene3D G3DSA:1.20.140.10 226 382 3.2E-65 T 16-09-2016 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 SUPERFAMILY SSF56645 2 247 4.71E-78 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS11770 9f0c5559246a9a986a9a1dde7da00b65 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.2E-36 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 1 362 29.387 T 16-09-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 191 342 4.3E-37 T 16-09-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 PANTHER PTHR21015:SF22 1 375 2.6E-93 T 16-09-2016 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 2 137 1.2E-28 T 16-09-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 Gene3D G3DSA:3.40.50.2000 2 189 6.2E-48 T 16-09-2016 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 PANTHER PTHR21015 1 375 2.6E-93 T 16-09-2016 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 SUPERFAMILY SSF53756 2 362 6.87E-88 T 16-09-2016 Spa2297_RS28440 d666242ac55f110fbf368029ed93a881 376 Gene3D G3DSA:3.40.50.2000 190 347 4.1E-26 T 16-09-2016 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Gene3D G3DSA:3.30.70.270 162 338 1.0E-49 T 16-09-2016 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SMART SM00086 109 150 0.0039 T 16-09-2016 IPR001610 PAC motif Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 PANTHER PTHR33121:SF13 294 615 6.6E-85 T 16-09-2016 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Gene3D G3DSA:3.30.450.20 31 148 1.8E-17 T 16-09-2016 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 PANTHER PTHR33121 294 615 6.6E-85 T 16-09-2016 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 158 331 9.2E-31 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Pfam PF00563 EAL domain 350 605 1.7E-63 T 16-09-2016 IPR001633 EAL domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SMART SM00267 150 333 1.6E-47 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SUPERFAMILY SSF141868 350 615 7.32E-79 T 16-09-2016 IPR001633 EAL domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 328 3.8E-38 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SUPERFAMILY SSF55073 167 335 1.1E-37 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Gene3D G3DSA:3.20.20.450 347 616 1.1E-104 T 16-09-2016 IPR001633 EAL domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 Pfam PF08448 PAS fold 42 152 4.8E-11 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SUPERFAMILY SSF55785 26 148 2.26E-18 T 16-09-2016 IPR000014 PAS domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 157 1.5E-17 T 16-09-2016 IPR000014 PAS domain Spa2297_RS12020 a3b22e695df6721e15a5687903e749f5 631 SMART SM00052 343 610 5.3E-102 T 16-09-2016 IPR001633 EAL domain Spa2297_RS31710 3aa547fcebc0081115056a0d1795c297 226 SUPERFAMILY SSF48317 16 215 2.09E-24 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS31710 3aa547fcebc0081115056a0d1795c297 226 Pfam PF01569 PAP2 superfamily 79 207 3.2E-13 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS31710 3aa547fcebc0081115056a0d1795c297 226 SMART SM00014 76 203 0.0053 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS31710 3aa547fcebc0081115056a0d1795c297 226 Gene3D G3DSA:1.20.144.10 55 216 1.3E-19 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS08000 30df3a2ebc04a101dc4573cffcfbc54b 91 Pfam PF04149 Domain of unknown function (DUF397) 30 82 1.6E-14 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 Gene3D G3DSA:3.20.20.70 11 363 5.2E-100 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 PANTHER PTHR22893:SF9 325 372 1.6E-220 T 16-09-2016 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 PANTHER PTHR22893:SF9 1 308 1.6E-220 T 16-09-2016 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 PANTHER PTHR22893 325 372 1.6E-220 T 16-09-2016 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 SUPERFAMILY SSF51395 10 360 4.45E-94 T 16-09-2016 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 18 360 6.9E-61 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS14800 525af75ac8a58d5709b618083cde5a61 376 PANTHER PTHR22893 1 308 1.6E-220 T 16-09-2016 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.1E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.1E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 Gene3D G3DSA:1.20.120.530 95 223 4.3E-30 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 SUPERFAMILY SSF48008 96 223 3.92E-29 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 SMART SM00345 17 76 2.7E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 PANTHER PTHR11751 14 114 3.5E-23 T 16-09-2016 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 SUPERFAMILY SSF46785 7 92 2.89E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 Pfam PF07729 FCD domain 98 219 1.2E-26 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 SMART SM00895 98 220 2.4E-20 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.5E-19 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 Gene3D G3DSA:1.10.10.10 8 78 4.6E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10310 f48e17fdc432d6e3c74b2ba0f70358c8 235 PANTHER PTHR11751:SF382 14 114 3.5E-23 T 16-09-2016 Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PANTHER PTHR24322:SF459 16 141 8.7E-89 T 16-09-2016 Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.1E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.1E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.1E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 Gene3D G3DSA:3.40.50.720 7 251 5.4E-84 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PANTHER PTHR24322 16 141 8.7E-89 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 SUPERFAMILY SSF51735 6 251 1.4E-80 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PANTHER PTHR24322:SF459 157 189 8.7E-89 T 16-09-2016 Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PANTHER PTHR24322 157 189 8.7E-89 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.9E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 5.5E-61 T 16-09-2016 Spa2297_RS06560 f96dfc76c89be5b07ab3876fb7ce3716 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 188 7.3E-4 T 16-09-2016 Spa2297_RS21790 d2753f6ebd2ba1eaedb221f04e0d4a11 290 Gene3D G3DSA:3.40.50.1820 24 287 6.2E-38 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21790 d2753f6ebd2ba1eaedb221f04e0d4a11 290 SUPERFAMILY SSF53474 21 287 3.19E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21790 d2753f6ebd2ba1eaedb221f04e0d4a11 290 PANTHER PTHR10992 22 288 1.9E-41 T 16-09-2016 Spa2297_RS21790 d2753f6ebd2ba1eaedb221f04e0d4a11 290 Pfam PF12697 Alpha/beta hydrolase family 43 280 9.2E-18 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21790 d2753f6ebd2ba1eaedb221f04e0d4a11 290 PANTHER PTHR10992:SF107 22 288 1.9E-41 T 16-09-2016 Spa2297_RS17000 480f7c3cf37c4d2265752b5d3b9068b9 463 SUPERFAMILY SSF53300 281 440 7.79E-13 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS17000 480f7c3cf37c4d2265752b5d3b9068b9 463 Pfam PF10138 vWA found in TerF C terminus 279 459 7.2E-34 T 16-09-2016 IPR019303 vWA found in TerF C terminus Spa2297_RS17000 480f7c3cf37c4d2265752b5d3b9068b9 463 Gene3D G3DSA:3.40.50.410 282 432 8.9E-6 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 SUPERFAMILY SSF53474 3 252 1.61E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 Gene3D G3DSA:3.40.50.1820 287 498 5.7E-21 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 Pfam PF01738 Dienelactone hydrolase family 350 502 2.7E-4 T 16-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 Gene3D G3DSA:3.40.50.1820 3 254 5.1E-33 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 SUPERFAMILY SSF53474 290 496 5.07E-23 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30805 2915a3df37764bb611bc1ba7049a0f74 526 Pfam PF12697 Alpha/beta hydrolase family 5 248 2.4E-9 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 Gene3D G3DSA:3.90.230.10 239 497 2.4E-67 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 SUPERFAMILY SSF53092 70 234 4.55E-25 T 16-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 PANTHER PTHR10804:SF17 64 498 2.5E-115 T 16-09-2016 Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 SMART SM01011 69 208 2.2E-36 T 16-09-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 Pfam PF00557 Metallopeptidase family M24 242 476 5.8E-49 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 410 422 - T 16-09-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 Pfam PF05195 Aminopeptidase P, N-terminal domain 75 193 1.5E-18 T 16-09-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 SUPERFAMILY SSF55920 235 497 4.45E-67 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 Gene3D G3DSA:3.40.350.10 69 238 5.1E-37 T 16-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Spa2297_RS16170 0bd86697b8a5a04db665dd183c85f79c 502 PANTHER PTHR10804 64 498 2.5E-115 T 16-09-2016 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 16-09-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 Gene3D G3DSA:3.30.63.10 47 98 1.1E-27 T 16-09-2016 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 Hamap MF_00328 Guanylate kinase [gmk]. 15 197 33.731 T 16-09-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 PANTHER PTHR23117 1 193 2.1E-87 T 16-09-2016 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 SUPERFAMILY SSF52540 14 193 4.43E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 18 193 6.0E-69 T 16-09-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 Pfam PF00625 Guanylate kinase 17 190 1.5E-44 T 16-09-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 Gene3D G3DSA:3.40.50.300 99 193 2.3E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 Gene3D G3DSA:3.40.50.300 14 39 2.3E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05565 60ba6cfc9138fa8823ce39ab75f66bbc 197 SMART SM00072 16 197 2.3E-59 T 16-09-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Spa2297_RS08345 637f88d3fe2615ed006c793687b146b7 195 Gene3D G3DSA:1.10.10.10 11 87 3.0E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08345 637f88d3fe2615ed006c793687b146b7 195 SUPERFAMILY SSF46785 9 108 2.59E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08345 637f88d3fe2615ed006c793687b146b7 195 Pfam PF12840 Helix-turn-helix domain 15 69 5.1E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08345 637f88d3fe2615ed006c793687b146b7 195 SMART SM00418 13 96 2.4E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 Pfam PF03476 MOSC N-terminal beta barrel domain 4 119 3.5E-27 T 16-09-2016 IPR005303 MOSC, N-terminal beta barrel Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 Pfam PF03473 MOSC domain 145 272 3.2E-32 T 16-09-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 SUPERFAMILY SSF50800 4 52 3.98E-19 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 SUPERFAMILY SSF50800 154 274 3.98E-19 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 PANTHER PTHR14237 3 274 1.5E-79 T 16-09-2016 Spa2297_RS03400 79bf591988f8fe428d07344d48380f5e 275 SUPERFAMILY SSF141673 6 135 3.27E-30 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 1.1E-20 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 1.1E-20 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 1.1E-20 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 1.1E-20 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 16-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PANTHER PTHR11444 30 447 4.9E-173 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 Gene3D G3DSA:1.20.200.10 109 373 1.7E-100 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 Pfam PF00206 Lyase 29 303 2.0E-35 T 16-09-2016 IPR022761 Fumarate lyase, N-terminal Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 5.1E-6 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 5.1E-6 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 5.1E-6 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 SUPERFAMILY SSF48557 15 445 3.93E-94 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 Gene3D G3DSA:1.10.40.30 374 444 1.7E-17 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 SMART SM00998 369 444 4.1E-14 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 Gene3D G3DSA:1.10.275.10 19 108 5.5E-27 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 443 4.5E-13 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 PANTHER PTHR11444:SF21 30 447 4.9E-173 T 16-09-2016 Spa2297_RS27875 31f8e99011e1f635c36d1ccab29ba9d8 447 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 16 354 3.0E-132 T 16-09-2016 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 SUPERFAMILY SSF55816 373 585 4.45E-40 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PANTHER PTHR11575:SF6 37 596 3.5E-196 T 16-09-2016 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 Pfam PF00149 Calcineurin-like phosphoesterase 48 295 1.4E-12 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 Gene3D G3DSA:3.90.780.10 376 585 1.7E-38 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 Pfam PF02872 5'-nucleotidase, C-terminal domain 376 555 5.7E-30 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PRINTS PR01607 Apyrase family signature 439 462 1.9E-21 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PRINTS PR01607 Apyrase family signature 46 64 1.9E-21 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PRINTS PR01607 Apyrase family signature 278 301 1.9E-21 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PRINTS PR01607 Apyrase family signature 530 549 1.9E-21 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PRINTS PR01607 Apyrase family signature 245 262 1.9E-21 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 ProSitePatterns PS00786 5'-nucleotidase signature 2. 143 154 - T 16-09-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 Gene3D G3DSA:3.60.21.10 43 375 5.5E-80 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 PANTHER PTHR11575 37 596 3.5E-196 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS08200 71104fe0e4c0abe66f6ee6f81299df65 602 SUPERFAMILY SSF56300 43 375 1.6E-76 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 PANTHER PTHR30055:SF49 7 193 5.1E-83 T 16-09-2016 Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 Gene3D G3DSA:1.10.357.10 12 193 1.3E-35 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 68 8.5E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 SUPERFAMILY SSF46689 14 85 2.54E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 PANTHER PTHR30055 7 193 5.1E-83 T 16-09-2016 Spa2297_RS03825 67d36ae837c10e91d5243439ebea98e5 196 SUPERFAMILY SSF48498 88 194 2.22E-12 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 PANTHER PTHR21021:SF15 238 506 7.0E-105 T 16-09-2016 Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 PANTHER PTHR21021 238 506 7.0E-105 T 16-09-2016 Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 SUPERFAMILY SSF55781 180 256 3.05E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 Gene3D G3DSA:3.30.450.40 96 254 2.2E-12 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 SMART SM00331 274 497 4.0E-31 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02610 b1c542b4128606f4a868148c2ad1dc4a 516 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 310 496 1.3E-40 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 29.297 T 16-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 SUPERFAMILY SSF51735 4 135 9.51E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 SUPERFAMILY SSF55347 109 217 2.18E-38 T 16-09-2016 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 PANTHER PTHR20836 1 250 4.5E-79 T 16-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 7.0E-27 T 16-09-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 16-09-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 6.7E-23 T 16-09-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 PIRSF PIRSF000161 2 250 5.4E-61 T 16-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 Gene3D G3DSA:3.40.50.720 3 143 1.3E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24240 43d9ae1d879a0680518a858c712aed37 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 41 248 1.5E-51 T 16-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 PANTHER PTHR10849 12 158 1.6E-88 T 16-09-2016 Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 Gene3D G3DSA:1.10.1060.10 18 122 5.5E-16 T 16-09-2016 Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 Pfam PF00037 4Fe-4S binding domain 103 123 8.3E-9 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 108 119 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 SUPERFAMILY SSF54862 42 151 1.05E-18 T 16-09-2016 Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 59 70 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 PANTHER PTHR10849:SF21 12 158 1.6E-88 T 16-09-2016 Spa2297_RS19465 47dfec3a7d9c796face139c73da65385 200 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 168 24.379 T 16-09-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 PANTHER PTHR22604 13 363 2.5E-114 T 16-09-2016 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 PANTHER PTHR22604:SF53 13 363 2.5E-114 T 16-09-2016 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 Gene3D G3DSA:3.40.50.720 13 143 3.1E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 Gene3D G3DSA:3.30.360.10 144 358 8.8E-40 T 16-09-2016 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 147 242 3.1E-12 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 SUPERFAMILY SSF51735 7 170 2.46E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 133 1.4E-23 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS12205 725602f376b8b3b5886d8467ae003cad 363 SUPERFAMILY SSF55347 142 270 4.09E-28 T 16-09-2016 Spa2297_RS00960 4428578bf5106325e603b543987fdcde 149 Pfam PF07681 DoxX 20 92 1.8E-6 T 16-09-2016 IPR032808 DoxX family Spa2297_RS00960 4428578bf5106325e603b543987fdcde 149 PANTHER PTHR33452:SF4 1 133 7.3E-45 T 16-09-2016 Spa2297_RS00960 4428578bf5106325e603b543987fdcde 149 PANTHER PTHR33452 1 133 7.3E-45 T 16-09-2016 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 367 560 5.2E-55 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 Pfam PF01590 GAF domain 205 310 2.0E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 SMART SM00331 341 560 3.1E-43 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 PANTHER PTHR21021:SF19 242 560 1.8E-59 T 16-09-2016 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 SUPERFAMILY SSF55785 10 118 5.23E-12 T 16-09-2016 IPR000014 PAS domain Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 Gene3D G3DSA:3.30.450.20 10 119 3.2E-14 T 16-09-2016 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 PANTHER PTHR21021 242 560 1.8E-59 T 16-09-2016 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 SUPERFAMILY SSF55781 214 321 5.23E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 SUPERFAMILY SSF81606 352 560 6.28E-11 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 SMART SM00065 135 320 5.2E-5 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 Pfam PF08448 PAS fold 17 120 2.0E-16 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS25990 59830de082dddd972816b13635c8b835 560 Gene3D G3DSA:3.30.450.40 134 318 6.4E-33 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PANTHER PTHR11712 3 402 2.1E-36 T 16-09-2016 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 Gene3D G3DSA:1.10.630.10 7 402 2.5E-74 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 SUPERFAMILY SSF48264 10 402 1.96E-53 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PRINTS PR00359 B-class P450 signature 294 321 1.1E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PRINTS PR00359 B-class P450 signature 342 351 1.1E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PRINTS PR00359 B-class P450 signature 148 164 1.1E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PRINTS PR00359 B-class P450 signature 198 220 1.1E-12 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12315 dce8d0c877dd3e83a31cedb5d97d6a15 406 PANTHER PTHR11712:SF282 3 402 2.1E-36 T 16-09-2016 Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 Gene3D G3DSA:3.90.550.10 5 179 2.6E-24 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 207 22.471 T 16-09-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 199 3.5E-53 T 16-09-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 Pfam PF01983 Guanylyl transferase CofC like 5 190 1.8E-10 T 16-09-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 PANTHER PTHR40392:SF1 2 210 4.1E-59 T 16-09-2016 Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 SUPERFAMILY SSF53448 4 201 4.13E-28 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS23570 1614d73dfad16174d486a85061c3724a 212 PANTHER PTHR40392 2 210 4.1E-59 T 16-09-2016 Spa2297_RS02390 2506d2706c92c076571f1e2bb8adcc9d 161 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 104 5.6E-7 T 16-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 Spa2297_RS02390 2506d2706c92c076571f1e2bb8adcc9d 161 SUPERFAMILY SSF53927 9 158 6.82E-29 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS02390 2506d2706c92c076571f1e2bb8adcc9d 161 Gene3D G3DSA:3.40.140.10 10 158 9.3E-32 T 16-09-2016 Spa2297_RS02390 2506d2706c92c076571f1e2bb8adcc9d 161 PANTHER PTHR11079 10 113 1.0E-12 T 16-09-2016 Spa2297_RS07785 5dec268b986ed8fc14273f2b5b4a649a 378 Pfam PF04909 Amidohydrolase 182 367 1.1E-11 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS07785 5dec268b986ed8fc14273f2b5b4a649a 378 SUPERFAMILY SSF51556 59 166 1.45E-12 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS07785 5dec268b986ed8fc14273f2b5b4a649a 378 SUPERFAMILY SSF51556 195 368 1.45E-12 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS07785 5dec268b986ed8fc14273f2b5b4a649a 378 PANTHER PTHR20852 288 365 6.6E-19 T 16-09-2016 Spa2297_RS07785 5dec268b986ed8fc14273f2b5b4a649a 378 Gene3D G3DSA:3.20.20.140 1 368 7.6E-113 T 16-09-2016 Spa2297_RS30265 9855a8df179ecebb384939e5b887c1c8 356 PIRSF PIRSF035875 33 342 1.9E-103 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS30265 9855a8df179ecebb384939e5b887c1c8 356 PANTHER PTHR30213 25 354 1.0E-136 T 16-09-2016 Spa2297_RS30265 9855a8df179ecebb384939e5b887c1c8 356 PANTHER PTHR30213:SF2 25 354 1.0E-136 T 16-09-2016 Spa2297_RS30265 9855a8df179ecebb384939e5b887c1c8 356 Pfam PF03631 Virulence factor BrkB 65 322 3.6E-67 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS30265 9855a8df179ecebb384939e5b887c1c8 356 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 56 318 3.5E-38 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS14560 0bc4161a29766611e57e608f2c0f91cc 188 PANTHER PTHR13256 1 181 9.7E-68 T 16-09-2016 Spa2297_RS14560 0bc4161a29766611e57e608f2c0f91cc 188 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 2.6E-31 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14560 0bc4161a29766611e57e608f2c0f91cc 188 SUPERFAMILY SSF55729 3 177 2.09E-50 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14560 0bc4161a29766611e57e608f2c0f91cc 188 PANTHER PTHR13256:SF43 1 181 9.7E-68 T 16-09-2016 Spa2297_RS14560 0bc4161a29766611e57e608f2c0f91cc 188 Gene3D G3DSA:3.40.630.30 4 182 4.9E-56 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 Gene3D G3DSA:3.40.190.10 162 335 3.4E-28 T 16-09-2016 Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 Gene3D G3DSA:3.40.190.10 52 161 7.6E-13 T 16-09-2016 Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 SUPERFAMILY SSF53850 25 418 2.43E-44 T 16-09-2016 Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 PANTHER PTHR30061 1 420 1.8E-66 T 16-09-2016 Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 Pfam PF01547 Bacterial extracellular solute-binding protein 53 336 9.1E-32 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS32100 7b1b88b1b682698e1efdbaa14a11c877 422 PANTHER PTHR30061:SF1 1 420 1.8E-66 T 16-09-2016 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Gene3D G3DSA:3.40.50.300 298 435 8.5E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SMART SM01043 98 240 3.4E-42 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 PANTHER PTHR35807 1 325 1.3E-48 T 16-09-2016 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Gene3D G3DSA:1.25.40.10 109 223 8.5E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 80 4.5E-7 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 PRINTS PR00364 Disease resistance protein signature 315 330 9.8E-6 T 16-09-2016 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 PRINTS PR00364 Disease resistance protein signature 400 414 9.8E-6 T 16-09-2016 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 PRINTS PR00364 Disease resistance protein signature 496 510 9.8E-6 T 16-09-2016 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Pfam PF03704 Bacterial transcriptional activator domain 98 240 6.9E-39 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Gene3D G3DSA:1.25.40.10 661 691 5.7E-11 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Gene3D G3DSA:1.25.40.10 837 1033 5.7E-11 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SUPERFAMILY SSF48452 835 980 3.75E-11 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SUPERFAMILY SSF48452 95 258 3.26E-28 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SUPERFAMILY SSF52540 283 562 2.1E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SUPERFAMILY SSF46894 7 91 1.08E-10 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Gene3D G3DSA:1.10.10.10 11 93 3.2E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 SMART SM00862 19 91 3.4E-10 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS09425 c92256bbccb8d501b2592b190e59025f 1127 Pfam PF13191 AAA ATPase domain 296 430 6.1E-8 T 16-09-2016 Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 SUPERFAMILY SSF141986 154 301 1.18E-37 T 16-09-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 PANTHER PTHR30237 8 309 1.7E-116 T 16-09-2016 Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 SUPERFAMILY SSF52317 9 168 1.1E-45 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 Pfam PF02016 LD-carboxypeptidase 19 295 9.0E-76 T 16-09-2016 IPR003507 Peptidase family S66 Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 Gene3D G3DSA:3.40.50.10740 6 167 5.0E-52 T 16-09-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 Gene3D G3DSA:3.50.30.60 176 303 1.1E-36 T 16-09-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 PIRSF PIRSF028757 7 309 4.3E-70 T 16-09-2016 IPR003507 Peptidase family S66 Spa2297_RS27015 07fa3270d35d73b984dff2d3d167b5a1 310 PANTHER PTHR30237:SF2 8 309 1.7E-116 T 16-09-2016 Spa2297_RS09395 e62bec97ee4d71a996feb8751a88be13 187 Gene3D G3DSA:3.90.1570.10 4 143 8.2E-20 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS09395 e62bec97ee4d71a996feb8751a88be13 187 PANTHER PTHR34107 10 137 7.9E-14 T 16-09-2016 Spa2297_RS09395 e62bec97ee4d71a996feb8751a88be13 187 SUPERFAMILY SSF52980 7 157 7.51E-19 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS09395 e62bec97ee4d71a996feb8751a88be13 187 Pfam PF05685 Putative restriction endonuclease 14 176 1.4E-17 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 PANTHER PTHR11986:SF7 2 381 4.2E-113 T 16-09-2016 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Gene3D G3DSA:3.40.640.10 145 266 2.0E-32 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 SUPERFAMILY SSF53383 9 373 5.17E-82 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Gene3D G3DSA:3.90.1150.10 5 54 8.2E-42 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Gene3D G3DSA:3.90.1150.10 270 375 8.2E-42 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 PANTHER PTHR11986 2 381 4.2E-113 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Pfam PF00202 Aminotransferase class-III 17 131 9.3E-14 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Pfam PF00202 Aminotransferase class-III 153 373 5.3E-47 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24550 e5aa9e21ea42e01689a491cce0412ad1 393 Gene3D G3DSA:3.40.640.10 55 132 4.0E-6 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS08830 fc218e669e4d44ce92434d4dc6c89d74 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 12 466 2.3E-28 T 16-09-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 Spa2297_RS08830 fc218e669e4d44ce92434d4dc6c89d74 471 PANTHER PTHR10283 1 466 4.3E-38 T 16-09-2016 Spa2297_RS06900 10e040fd87ca1923e0b77d1eec96a1ed 338 SUPERFAMILY SSF48317 38 244 8.63E-29 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06900 10e040fd87ca1923e0b77d1eec96a1ed 338 SMART SM00014 113 229 1.6E-8 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06900 10e040fd87ca1923e0b77d1eec96a1ed 338 Gene3D G3DSA:1.20.144.10 89 236 2.1E-19 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06900 10e040fd87ca1923e0b77d1eec96a1ed 338 Pfam PF01569 PAP2 superfamily 116 231 4.4E-20 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06900 10e040fd87ca1923e0b77d1eec96a1ed 338 PANTHER PTHR14969 59 252 7.9E-22 T 16-09-2016 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 PIRSF PIRSF021524 12 308 5.6E-112 T 16-09-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 PANTHER PTHR23091:SF235 136 305 8.7E-63 T 16-09-2016 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 SUPERFAMILY SSF55729 16 304 8.35E-52 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 Pfam PF00583 Acetyltransferase (GNAT) family 218 295 5.7E-13 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 Pfam PF00583 Acetyltransferase (GNAT) family 68 137 2.3E-6 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 Gene3D G3DSA:3.40.630.30 165 304 4.4E-31 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 18 304 1.2E-118 T 16-09-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 15 306 36.559 T 16-09-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 Gene3D G3DSA:3.40.630.30 18 145 5.8E-13 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15420 35a55753f30fb9ece2280f55e6b54f0d 308 PANTHER PTHR23091 136 305 8.7E-63 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 Pfam PF11838 ERAP1-like C-terminal domain 535 846 3.0E-62 T 16-09-2016 IPR024571 ERAP1-like C-terminal domain Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PANTHER PTHR11533 39 601 6.2E-167 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PANTHER PTHR11533:SF190 39 601 6.2E-167 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PANTHER PTHR11533:SF190 628 719 6.2E-167 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 140 155 1.2E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 335 1.2E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 1.2E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 304 319 1.2E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 270 280 1.2E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 SUPERFAMILY SSF63737 8 199 4.58E-35 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 851 0.0 T 16-09-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 Gene3D G3DSA:1.10.390.10 317 464 1.5E-40 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 PANTHER PTHR11533 628 719 6.2E-167 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 SUPERFAMILY SSF55486 218 462 4.98E-73 T 16-09-2016 Spa2297_RS11160 81cabdd4b9dc2697dafe2fc40c1948eb 856 Pfam PF01433 Peptidase family M1 90 396 1.3E-60 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 PANTHER PTHR13078:SF54 1 263 1.1E-79 T 16-09-2016 Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 PANTHER PTHR13078 1 263 1.1E-79 T 16-09-2016 Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 Gene3D G3DSA:3.10.129.10 73 156 1.1E-5 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 Pfam PF01575 MaoC like domain 198 241 2.0E-10 T 16-09-2016 IPR002539 MaoC-like domain Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 SUPERFAMILY SSF54637 69 175 1.49E-7 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 SUPERFAMILY SSF54637 180 286 2.65E-18 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS18885 95261d7eb2b5fbe38b356d90c9bbc7b3 293 Gene3D G3DSA:3.10.129.10 157 263 1.5E-18 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 Gene3D G3DSA:1.10.10.10 100 144 5.8E-4 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 Gene3D G3DSA:1.10.10.10 146 189 5.6E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 Hamap MF_01114 Regulatory protein RecX [recX]. 79 247 15.435 T 16-09-2016 IPR003783 Regulatory protein RecX GO:0006282 Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 Pfam PF02631 RecX family 122 242 4.5E-29 T 16-09-2016 IPR003783 Regulatory protein RecX GO:0006282 Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 PANTHER PTHR33602:SF1 97 252 6.4E-41 T 16-09-2016 Spa2297_RS24410 feb1c5ffb5ebae47d605eeaa1b873fb2 259 PANTHER PTHR33602 97 252 6.4E-41 T 16-09-2016 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 PANTHER PTHR34218 4 106 5.0E-170 T 16-09-2016 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 Gene3D G3DSA:1.10.439.10 3 153 6.2E-33 T 16-09-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 Gene3D G3DSA:2.30.120.10 275 349 4.3E-7 T 16-09-2016 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 Gene3D G3DSA:3.60.20.10 362 536 1.2E-88 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 Gene3D G3DSA:3.60.20.10 154 274 1.2E-88 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 PANTHER PTHR34218:SF2 129 729 5.0E-170 T 16-09-2016 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 PIRSF PIRSF001227 1 730 4.0E-247 T 16-09-2016 IPR014395 Penicillin acylase GO:0016811 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 Pfam PF01804 Penicillin amidase 3 725 2.0E-184 T 16-09-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 PANTHER PTHR34218 129 729 5.0E-170 T 16-09-2016 Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 SUPERFAMILY SSF56235 2 726 1.88E-141 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15905 e28afac22e3097cf4a24841470672fe9 730 PANTHER PTHR34218:SF2 4 106 5.0E-170 T 16-09-2016 Spa2297_RS28865 79d52e30d85b7e7fade2b2969091c6fe 446 Pfam PF06974 Protein of unknown function (DUF1298) 295 440 8.9E-21 T 16-09-2016 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|UniPathway: UPA00282 Spa2297_RS28865 79d52e30d85b7e7fade2b2969091c6fe 446 PANTHER PTHR31650:SF1 4 443 6.9E-86 T 16-09-2016 Spa2297_RS28865 79d52e30d85b7e7fade2b2969091c6fe 446 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 6 252 3.0E-58 T 16-09-2016 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|UniPathway: UPA00282 Spa2297_RS28865 79d52e30d85b7e7fade2b2969091c6fe 446 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 6 444 9.4E-123 T 16-09-2016 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|UniPathway: UPA00282 Spa2297_RS28865 79d52e30d85b7e7fade2b2969091c6fe 446 PANTHER PTHR31650 4 443 6.9E-86 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 SUPERFAMILY SSF52540 19 245 4.94E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 SMART SM00382 61 182 1.8E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Gene3D G3DSA:1.10.8.60 178 251 1.8E-8 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 SUPERFAMILY SSF48019 262 444 1.53E-74 T 16-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 441 1.6E-70 T 16-09-2016 IPR021886 MgsA AAA+ ATPase C-terminal Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 9.3E-14 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Gene3D G3DSA:3.40.50.300 11 170 2.1E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 PANTHER PTHR13779 7 443 2.7E-187 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 PANTHER PTHR13779:SF7 7 443 2.7E-187 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Gene3D G3DSA:1.10.3710.10 357 445 1.8E-28 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Gene3D G3DSA:1.20.272.10 258 356 2.0E-45 T 16-09-2016 Spa2297_RS05695 9ae6e5767c31b45e82c9ed17ec10c0da 451 Pfam PF16193 AAA C-terminal domain 200 276 2.4E-25 T 16-09-2016 IPR032423 AAA ATPase, C-terminal domain Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 Pfam PF07883 Cupin domain 120 184 1.2E-15 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 Gene3D G3DSA:2.60.120.10 120 184 4.6E-14 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 SUPERFAMILY SSF51182 75 182 4.01E-20 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 PANTHER PTHR10245:SF20 7 195 1.6E-34 T 16-09-2016 Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 PANTHER PTHR10245 7 195 1.6E-34 T 16-09-2016 Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 Gene3D G3DSA:1.10.260.40 7 77 1.3E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 SUPERFAMILY SSF47413 7 75 1.75E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 SMART SM00530 16 71 3.6E-18 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS19995 c60495ce335ab6a430603b17edbe1f52 205 Pfam PF13560 Helix-turn-helix domain 13 71 3.5E-16 T 16-09-2016 Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 SMART SM01012 166 221 2.3E-18 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 PIRSF PIRSF036625 2 233 5.6E-74 T 16-09-2016 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 Pfam PF13185 GAF domain 17 138 4.4E-10 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 Gene3D G3DSA:3.30.450.40 10 167 2.4E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 Gene3D G3DSA:1.10.10.10 169 224 2.1E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 SUPERFAMILY SSF55781 20 166 4.17E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 SUPERFAMILY SSF52172 148 220 1.74E-7 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16010 bc60ab6343a30ae9d86386494aec9688 233 Pfam PF03861 ANTAR domain 169 221 2.1E-16 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 500 3.8E-215 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 PANTHER PTHR10196:SF69 7 509 6.7E-263 T 16-09-2016 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 Gene3D G3DSA:3.30.420.40 6 256 6.9E-103 T 16-09-2016 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 Gene3D G3DSA:3.30.420.40 258 502 8.6E-98 T 16-09-2016 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 454 4.7E-64 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 PANTHER PTHR10196 7 509 6.7E-263 T 16-09-2016 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 Hamap MF_00186 Glycerol kinase [glpK]. 6 501 54.596 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 SUPERFAMILY SSF53067 7 258 2.16E-90 T 16-09-2016 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 255 1.2E-73 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 PIRSF PIRSF000538 6 505 6.2E-163 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS05165 a8b1028fd4d90b32d318cfd1deb54a0a 511 SUPERFAMILY SSF53067 258 501 1.2E-79 T 16-09-2016 Spa2297_RS19030 815c946d5e054a487811919419c86985 301 SUPERFAMILY SSF52540 3 230 1.82E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19030 815c946d5e054a487811919419c86985 301 Gene3D G3DSA:3.40.50.300 3 229 8.5E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 PANTHER PTHR11751:SF436 19 107 2.9E-22 T 16-09-2016 Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 PANTHER PTHR11751 19 107 2.9E-22 T 16-09-2016 Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 1.5E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 Gene3D G3DSA:1.20.120.530 84 216 4.5E-26 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 Pfam PF07729 FCD domain 92 212 1.9E-22 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 SMART SM00895 90 214 6.3E-15 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 Gene3D G3DSA:1.10.10.10 14 81 3.4E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 SMART SM00345 22 80 2.1E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 SUPERFAMILY SSF48008 88 218 7.59E-26 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS27790 7b516a110056c329a3acb571008e107d 229 SUPERFAMILY SSF46785 16 84 7.68E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 Pfam PF00072 Response regulator receiver domain 3 108 6.0E-18 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 Gene3D G3DSA:1.10.10.10 151 213 6.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 PANTHER PTHR26402:SF582 1 211 5.6E-84 T 16-09-2016 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 200 2.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 PANTHER PTHR26402 1 211 5.6E-84 T 16-09-2016 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 7.8E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 7.8E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 7.8E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 SMART SM00421 148 205 7.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 SUPERFAMILY SSF52172 1 154 3.56E-19 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 Gene3D G3DSA:3.40.50.2300 1 150 4.0E-26 T 16-09-2016 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 SUPERFAMILY SSF46894 132 203 5.44E-16 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS14110 152f9d4e0706c663a59ef4256e15a499 214 SMART SM00448 1 120 3.2E-11 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 Pfam PF00668 Condensation domain 2 45 2.2E-6 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 PANTHER PTHR24095 1 546 2.5E-171 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 PANTHER PTHR24095:SF137 1 546 2.5E-171 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 SUPERFAMILY SSF52777 1 180 3.34E-41 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 356 367 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 Gene3D G3DSA:3.40.50.980 380 524 2.4E-37 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 Pfam PF00501 AMP-binding enzyme 216 546 5.5E-75 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 PRINTS PR00154 AMP-binding signature 363 371 6.2E-5 T 16-09-2016 IPR020459 AMP-binding Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 PRINTS PR00154 AMP-binding signature 351 362 6.2E-5 T 16-09-2016 IPR020459 AMP-binding Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 Pfam PF13745 HxxPF-repeated domain 67 162 1.0E-31 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 SUPERFAMILY SSF56801 176 546 1.24E-91 T 16-09-2016 Spa2297_RS34245 33f61969b373b5ba645d4223417d22af 546 Gene3D G3DSA:3.40.50.980 212 379 1.6E-49 T 16-09-2016 Spa2297_RS21855 8cd01f4adcdf2fdff3cd47c63436b3d4 249 Pfam PF12138 Spherulation-specific family 4 47 242 4.7E-20 T 16-09-2016 IPR021986 Spherulation-specific family 4 Spa2297_RS21855 8cd01f4adcdf2fdff3cd47c63436b3d4 249 PANTHER PTHR35040:SF3 1 249 1.1E-170 T 16-09-2016 Spa2297_RS21855 8cd01f4adcdf2fdff3cd47c63436b3d4 249 PANTHER PTHR35040 1 249 1.1E-170 T 16-09-2016 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 Pfam PF00892 EamA-like transporter family 150 283 6.8E-8 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 Pfam PF00892 EamA-like transporter family 7 139 2.7E-10 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 SUPERFAMILY SSF103481 198 283 2.88E-7 T 16-09-2016 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 PANTHER PTHR12715:SF12 1 285 7.0E-70 T 16-09-2016 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 PANTHER PTHR12715 1 285 7.0E-70 T 16-09-2016 Spa2297_RS01735 56e89937fcce803f36e9620dbfb83fe5 320 SUPERFAMILY SSF103481 44 145 3.4E-7 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PANTHER PTHR22939:SF79 218 668 1.7E-149 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 Gene3D G3DSA:2.40.10.10 379 457 1.3E-27 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 Pfam PF13365 Trypsin-like peptidase domain 384 530 4.8E-34 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 Gene3D G3DSA:2.40.10.10 458 580 1.4E-42 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 SMART SM00228 579 655 2.1E-8 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 458 482 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 523 540 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 613 625 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 393 405 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 501 518 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PRINTS PR00834 HtrA/DegQ protease family signature 417 437 3.7E-44 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 SUPERFAMILY SSF50156 560 662 1.22E-17 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 PANTHER PTHR22939 218 668 1.7E-149 T 16-09-2016 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 Gene3D G3DSA:2.30.42.10 581 667 6.8E-18 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 Pfam PF13180 PDZ domain 579 662 1.2E-17 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21715 779d826f5059a72d2b81ade1f84100a5 670 SUPERFAMILY SSF50494 357 571 4.58E-54 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.3E-9 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 1.3E-9 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.3E-9 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.3E-9 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Pfam PF13620 Carboxypeptidase regulatory-like domain 587 661 3.4E-11 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Pfam PF13620 Carboxypeptidase regulatory-like domain 670 750 2.2E-11 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Pfam PF13620 Carboxypeptidase regulatory-like domain 755 830 1.5E-11 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF103473 246 418 4.97E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF103473 8 193 4.97E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF103473 468 492 4.97E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF49464 669 762 4.9E-14 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:2.60.40.1120 670 757 1.8E-14 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:2.60.40.1120 587 658 5.0E-10 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PANTHER PTHR23501 1 512 3.8E-194 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 490 1.9E-70 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF49478 757 817 5.1E-11 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Pfam PF07690 Major Facilitator Superfamily 13 181 7.6E-31 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Pfam PF07690 Major Facilitator Superfamily 196 408 3.1E-18 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:1.20.1250.20 469 495 3.9E-23 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:1.20.1250.20 13 182 1.3E-28 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:1.20.1250.20 252 420 3.9E-23 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 PANTHER PTHR23501:SF73 1 512 3.8E-194 T 16-09-2016 Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 SUPERFAMILY SSF49464 587 665 1.53E-10 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS16000 8fbc04fbecd02740e3a15c6ba0daa210 835 Gene3D G3DSA:2.60.40.10 758 807 4.3E-13 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS07725 4cc94a2ad3f3f465c864c43a76d6f91f 110 PANTHER PTHR13696 1 110 4.1E-18 T 16-09-2016 Spa2297_RS07725 4cc94a2ad3f3f465c864c43a76d6f91f 110 Pfam PF01883 Domain of unknown function DUF59 12 72 1.2E-18 T 16-09-2016 IPR002744 Domain of unknown function DUF59 Spa2297_RS07725 4cc94a2ad3f3f465c864c43a76d6f91f 110 PANTHER PTHR13696:SF62 1 110 4.1E-18 T 16-09-2016 Spa2297_RS07725 4cc94a2ad3f3f465c864c43a76d6f91f 110 SUPERFAMILY SSF117916 8 104 9.16E-28 T 16-09-2016 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 Gene3D G3DSA:3.40.50.720 173 287 1.8E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 Pfam PF00107 Zinc-binding dehydrogenase 174 301 1.6E-22 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 SUPERFAMILY SSF50129 2 173 8.52E-51 T 16-09-2016 IPR011032 GroES-like Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 SUPERFAMILY SSF51735 142 297 4.44E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 PANTHER PTHR11695:SF285 13 340 1.2E-132 T 16-09-2016 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 2.6E-31 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 PANTHER PTHR11695 13 340 1.2E-132 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 56.675 T 16-09-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378|UniPathway: UPA00046 Spa2297_RS28320 2e6ba7f4c33c8b3729ae313753116a0b 342 Gene3D G3DSA:3.90.180.10 2 172 7.8E-48 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 2.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 262 4.5E-64 T 16-09-2016 Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PANTHER PTHR24322 171 203 5.7E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PANTHER PTHR24322 26 155 5.7E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 Gene3D G3DSA:3.40.50.720 14 263 1.8E-81 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 SUPERFAMILY SSF51735 18 263 5.09E-77 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01885 c1b822129131ff309b9971291222a7a1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SUPERFAMILY SSF55874 786 869 5.33E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Pfam PF13581 Histidine kinase-like ATPase domain 762 868 1.4E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Pfam PF13188 PAS domain 218 267 9.8E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SMART SM00331 528 748 2.0E-29 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 PANTHER PTHR21021:SF19 452 757 2.0E-57 T 16-09-2016 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Gene3D G3DSA:3.30.450.40 333 508 4.4E-35 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Pfam PF01590 GAF domain 401 500 1.7E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SMART SM00065 368 510 2.6E-7 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Gene3D G3DSA:3.30.450.20 218 314 6.7E-4 T 16-09-2016 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SUPERFAMILY SSF55781 389 504 1.53E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SUPERFAMILY SSF81606 542 747 3.14E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 PANTHER PTHR21021 452 757 2.0E-57 T 16-09-2016 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 SUPERFAMILY SSF103190 41 169 3.92E-29 T 16-09-2016 IPR029151 Periplasmic sensor domain-like Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Pfam PF17203 Single cache domain 3 36 170 1.6E-24 T 16-09-2016 IPR033463 Single cache domain 3 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Gene3D G3DSA:3.30.450.20 33 174 1.4E-36 T 16-09-2016 Spa2297_RS00620 7ae78d1b5f50f7875efb8a8c746c5adb 882 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 556 748 3.0E-49 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 Gene3D G3DSA:1.20.1290.10 18 146 1.3E-44 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 96 8.7E-20 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 1.3E-21 T 16-09-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 PANTHER PTHR34846 23 142 2.0E-13 T 16-09-2016 Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 SUPERFAMILY SSF69118 24 145 5.37E-37 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS11590 01daa2eb5a341128d9ae6b361d601ebd 161 PANTHER PTHR34846:SF2 23 142 2.0E-13 T 16-09-2016 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SUPERFAMILY SSF158472 188 234 2.22E-5 T 16-09-2016 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SMART SM00304 187 240 7.8E-4 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PANTHER PTHR24423 4 15 1.3E-66 T 16-09-2016 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PANTHER PTHR24423 181 458 1.3E-66 T 16-09-2016 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 1.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 1.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 1.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SUPERFAMILY SSF47384 224 306 3.92E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SMART SM00388 241 308 1.2E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 Gene3D G3DSA:1.10.287.130 233 294 1.8E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SUPERFAMILY SSF55874 297 458 6.02E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 Gene3D G3DSA:3.30.565.10 295 459 7.7E-39 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 SMART SM00387 350 460 2.9E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 307 1.1E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 459 3.4E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03225 336efcf9cc39e3a199d00d780fa8c503 462 Pfam PF00672 HAMP domain 169 233 1.6E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS13895 7bf0f4e4c1e1e295739a237fc4e213eb 410 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 36 386 1.0E-93 T 16-09-2016 IPR010640 Low temperature requirement A Spa2297_RS13895 7bf0f4e4c1e1e295739a237fc4e213eb 410 PANTHER PTHR36840 14 406 3.0E-84 T 16-09-2016 Spa2297_RS13895 7bf0f4e4c1e1e295739a237fc4e213eb 410 PANTHER PTHR36840:SF1 14 406 3.0E-84 T 16-09-2016 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 SUPERFAMILY SSF74650 10 258 8.79E-63 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 Gene3D G3DSA:1.50.10.10 306 707 3.3E-124 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 Gene3D G3DSA:2.70.98.40 5 259 5.6E-82 T 16-09-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 PANTHER PTHR11051:SF9 5 790 0.0 T 16-09-2016 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 725 778 3.6E-9 T 16-09-2016 IPR005194 Glycoside hydrolase family 65, C-terminal Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 SUPERFAMILY SSF48208 262 769 1.13E-94 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 PANTHER PTHR11051 5 790 0.0 T 16-09-2016 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 10 257 2.1E-66 T 16-09-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 309 721 6.8E-152 T 16-09-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 Spa2297_RS30585 60e1c265807d1cf86b8708b7dbd6458f 790 PIRSF PIRSF036289 1 790 2.7E-218 T 16-09-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 PANTHER PTHR24362:SF160 425 513 2.0E-128 T 16-09-2016 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 Pfam PF00069 Protein kinase domain 19 274 2.7E-47 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 SMART SM00220 19 281 1.3E-56 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 PANTHER PTHR24362 425 513 2.0E-128 T 16-09-2016 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 PANTHER PTHR24362 17 369 2.0E-128 T 16-09-2016 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 SUPERFAMILY SSF56112 17 278 3.64E-72 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 PANTHER PTHR24362:SF160 17 369 2.0E-128 T 16-09-2016 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 Gene3D G3DSA:1.10.510.10 87 276 8.7E-50 T 16-09-2016 Spa2297_RS16870 5051e18cf3a234ea2b8e065ac6ac861f 516 Gene3D G3DSA:3.30.200.20 15 86 3.5E-24 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 Gene3D G3DSA:3.50.50.60 266 346 4.2E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 Gene3D G3DSA:3.50.50.60 4 173 4.2E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 Pfam PF01494 FAD binding domain 3 341 3.0E-39 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 SUPERFAMILY SSF51905 3 168 6.31E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 SUPERFAMILY SSF51905 265 354 6.31E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PANTHER PTHR13789 3 361 2.0E-82 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 5.5E-27 T 16-09-2016 Spa2297_RS24425 69893081ec2c8d512df91350c65874bd 541 PANTHER PTHR13789:SF90 3 361 2.0E-82 T 16-09-2016 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 SUPERFAMILY SSF51735 182 408 6.78E-68 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 PANTHER PTHR23406:SF33 40 409 9.9E-278 T 16-09-2016 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 PANTHER PTHR23406 40 409 9.9E-278 T 16-09-2016 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 SMART SM01274 37 170 4.5E-78 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 Gene3D G3DSA:3.40.50.720 180 408 1.3E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 SUPERFAMILY SSF53223 32 180 1.01E-55 T 16-09-2016 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 SMART SM00919 182 402 1.2E-107 T 16-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 PIRSF PIRSF000106 39 409 2.2E-73 T 16-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 Pfam PF03949 Malic enzyme, NAD binding domain 184 383 2.0E-20 T 16-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 Pfam PF00390 Malic enzyme, N-terminal domain 134 170 3.7E-6 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 Pfam PF00390 Malic enzyme, N-terminal domain 39 132 2.9E-21 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS22270 2ed3239539f87bc703b7b9c236be9a57 409 Gene3D G3DSA:3.40.50.10380 35 179 7.5E-54 T 16-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spa2297_RS06335 446536bc7ac0ba7ebee3551e42b5e0e6 340 PANTHER PTHR34580:SF2 1 322 2.5E-191 T 16-09-2016 Spa2297_RS06335 446536bc7ac0ba7ebee3551e42b5e0e6 340 Pfam PF13280 WYL domain 146 313 1.3E-31 T 16-09-2016 IPR026881 WYL domain Spa2297_RS06335 446536bc7ac0ba7ebee3551e42b5e0e6 340 PIRSF PIRSF016838 1 321 1.4E-84 T 16-09-2016 IPR028349 Protein PafC Spa2297_RS06335 446536bc7ac0ba7ebee3551e42b5e0e6 340 PANTHER PTHR34580 1 322 2.5E-191 T 16-09-2016 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 Gene3D G3DSA:3.40.50.1980 57 196 3.0E-7 T 16-09-2016 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 PANTHER PTHR30535 43 331 5.1E-71 T 16-09-2016 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 Pfam PF01497 Periplasmic binding protein 61 310 2.8E-27 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 PANTHER PTHR30535:SF7 43 331 5.1E-71 T 16-09-2016 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 SUPERFAMILY SSF53807 57 331 2.2E-40 T 16-09-2016 Spa2297_RS31675 bc80ea8cdb1c83e0de148b36cfb8bd69 336 Gene3D G3DSA:3.40.50.1980 200 331 1.2E-30 T 16-09-2016 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 PANTHER PTHR30328:SF11 1 192 1.9E-31 T 16-09-2016 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 SUPERFAMILY SSF48498 82 193 1.24E-19 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 PANTHER PTHR30328 1 192 1.9E-31 T 16-09-2016 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.4E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 Gene3D G3DSA:1.10.357.10 9 194 4.1E-36 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.3E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.3E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 Pfam PF13977 Bacterial transcriptional repressor 85 194 1.1E-24 T 16-09-2016 Spa2297_RS28230 f12356cd753b999089ee0d4ed931d297 206 SUPERFAMILY SSF46689 4 86 3.03E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 36.224 T 16-09-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 Gene3D G3DSA:3.40.50.1970 13 175 4.3E-53 T 16-09-2016 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 SUPERFAMILY SSF56796 16 358 3.14E-96 T 16-09-2016 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 346 2.8E-105 T 16-09-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 Gene3D G3DSA:1.20.1090.10 177 357 7.8E-58 T 16-09-2016 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 PIRSF PIRSF001455 13 360 3.7E-97 T 16-09-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 Pfam PF01761 3-dehydroquinate synthase 71 327 2.8E-92 T 16-09-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS05640 ab1d211503288069ae143f69d78d66ec 363 PANTHER PTHR21090 2 358 7.3E-141 T 16-09-2016 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 Gene3D G3DSA:3.40.50.2300 190 344 3.9E-49 T 16-09-2016 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 PANTHER PTHR30146:SF45 10 346 9.0E-140 T 16-09-2016 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 SUPERFAMILY SSF53822 85 346 5.44E-57 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 SUPERFAMILY SSF47413 11 69 1.41E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 Gene3D G3DSA:1.10.260.40 10 60 1.6E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 2.2E-14 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 SMART SM00354 11 81 2.6E-20 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 Gene3D G3DSA:3.40.50.2300 61 189 7.1E-27 T 16-09-2016 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 Pfam PF13377 Periplasmic binding protein-like domain 184 342 3.7E-35 T 16-09-2016 Spa2297_RS31205 5805aa32cda082528a8435b226793a28 357 PANTHER PTHR30146 10 346 9.0E-140 T 16-09-2016 Spa2297_RS08055 cc2c0a002026b2c5c6763f163798c956 156 PANTHER PTHR13947:SF16 57 156 2.1E-17 T 16-09-2016 Spa2297_RS08055 cc2c0a002026b2c5c6763f163798c956 156 Gene3D G3DSA:3.40.630.30 12 155 5.4E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS08055 cc2c0a002026b2c5c6763f163798c956 156 PANTHER PTHR13947 57 156 2.1E-17 T 16-09-2016 Spa2297_RS08055 cc2c0a002026b2c5c6763f163798c956 156 SUPERFAMILY SSF55729 11 152 1.95E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS08055 cc2c0a002026b2c5c6763f163798c956 156 Pfam PF13508 Acetyltransferase (GNAT) domain 58 133 2.1E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS09405 aa71092778383eba801509037e78c694 350 SUPERFAMILY SSF56219 129 344 1.09E-26 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS09405 aa71092778383eba801509037e78c694 350 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 134 336 1.1E-16 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS09405 aa71092778383eba801509037e78c694 350 Gene3D G3DSA:3.60.10.10 128 281 1.3E-8 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 SUPERFAMILY SSF89550 6 68 4.32E-7 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 Pfam PF02811 PHP domain 6 181 3.0E-17 T 16-09-2016 IPR004013 PHP domain GO:0003824 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1043 2.3E-161 T 16-09-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 Pfam PF14579 Helix-hairpin-helix motif 830 922 2.0E-16 T 16-09-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 PANTHER PTHR32294:SF4 1 1155 0.0 T 16-09-2016 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 SMART SM00481 5 72 1.3E-20 T 16-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 344 756 2.3E-127 T 16-09-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 PANTHER PTHR32294 1 1155 0.0 T 16-09-2016 Spa2297_RS06840 2812583e8982bf096d455b7e49040a19 1159 Gene3D G3DSA:3.20.20.140 6 70 1.5E-7 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SUPERFAMILY SSF54980 595 676 1.87E-23 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SMART SM00838 595 681 5.1E-30 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Gene3D G3DSA:3.30.70.240 596 676 4.2E-25 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 181 1.8E-31 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Pfam PF03764 Elongation factor G, domain IV 474 592 3.7E-41 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115:SF66 253 281 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Pfam PF00679 Elongation factor G C-terminus 595 676 3.0E-24 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SUPERFAMILY SSF54211 474 591 9.1E-31 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SUPERFAMILY SSF54980 400 476 4.32E-19 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Pfam PF14492 Elongation Factor G, domain II 399 472 4.1E-26 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Gene3D G3DSA:3.30.230.10 479 595 2.0E-36 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Gene3D G3DSA:3.40.50.300 7 285 7.5E-95 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.6E-15 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PRINTS PR00315 GTP-binding elongation factor signature 95 106 2.6E-15 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.6E-15 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PRINTS PR00315 GTP-binding elongation factor signature 59 67 2.6E-15 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PRINTS PR00315 GTP-binding elongation factor signature 79 89 2.6E-15 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Gene3D G3DSA:2.40.30.10 301 400 3.0E-28 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SUPERFAMILY SSF52540 7 280 4.56E-95 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SUPERFAMILY SSF50447 264 398 1.35E-28 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Pfam PF03144 Elongation factor Tu domain 2 319 386 4.8E-14 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 SMART SM00889 475 593 4.0E-51 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Hamap MF_00054_B Elongation factor G [fusA]. 7 681 90.654 T 16-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 676 3.3E-235 T 16-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Pfam PF00009 Elongation factor Tu GTP binding domain 11 280 3.9E-64 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115 1 178 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115 299 675 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115 253 281 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115:SF66 1 178 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 PANTHER PTHR23115:SF66 299 675 2.7E-264 T 16-09-2016 Spa2297_RS27495 60552aafdde9b8b90ef8e64184315e15 681 Gene3D G3DSA:3.30.70.870 401 474 4.4E-27 T 16-09-2016 Spa2297_RS08070 52ab881b6408a61f1ac40c970f485c76 186 Gene3D G3DSA:3.10.290.10 55 146 6.9E-30 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS08070 52ab881b6408a61f1ac40c970f485c76 186 SMART SM00363 56 120 5.8E-7 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS08070 52ab881b6408a61f1ac40c970f485c76 186 SUPERFAMILY SSF55174 55 138 2.49E-23 T 16-09-2016 Spa2297_RS08070 52ab881b6408a61f1ac40c970f485c76 186 Pfam PF01479 S4 domain 56 102 6.1E-11 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 Gene3D G3DSA:3.40.50.1980 195 328 8.8E-24 T 16-09-2016 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 Gene3D G3DSA:3.40.50.1980 46 191 1.8E-15 T 16-09-2016 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 Pfam PF01497 Periplasmic binding protein 51 306 6.2E-38 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 PANTHER PTHR30535 30 328 2.9E-54 T 16-09-2016 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 SUPERFAMILY SSF53807 46 328 1.65E-41 T 16-09-2016 Spa2297_RS30470 2deef85a47ff7c3a6328171e39abf041 335 PANTHER PTHR30535:SF7 30 328 2.9E-54 T 16-09-2016 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 Pfam PF00005 ABC transporter 25 174 2.3E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 Pfam PF00005 ABC transporter 273 426 1.3E-18 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 PANTHER PTHR24220 11 381 5.1E-233 T 16-09-2016 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 PANTHER PTHR24220:SF502 11 381 5.1E-233 T 16-09-2016 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 SMART SM00382 281 475 4.6E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 SMART SM00382 34 222 9.7E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 SUPERFAMILY SSF52540 271 486 2.51E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 Gene3D G3DSA:3.40.50.300 7 229 7.2E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 SUPERFAMILY SSF52540 9 229 1.96E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11605 b8423301ed9c211242a060a2b6def6ac 511 Gene3D G3DSA:3.40.50.300 253 489 1.1E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 SUPERFAMILY SSF55920 206 256 1.88E-25 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 SUPERFAMILY SSF55920 11 166 1.88E-25 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 PANTHER PTHR10804:SF92 12 161 2.9E-80 T 16-09-2016 Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 Gene3D G3DSA:3.90.230.10 12 255 1.1E-25 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 Pfam PF00557 Metallopeptidase family M24 15 255 2.2E-27 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS16250 afdbc903da4bb4c11735259afe2ee685 280 PANTHER PTHR10804 12 161 2.9E-80 T 16-09-2016 Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 Pfam PF00588 SpoU rRNA Methylase family 120 264 3.5E-36 T 16-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 35 105 1.9E-10 T 16-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 Gene3D G3DSA:3.40.1280.10 116 271 1.9E-47 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 SUPERFAMILY SSF55315 8 106 2.12E-21 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 Gene3D G3DSA:3.30.1330.30 8 106 3.1E-27 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 PANTHER PTHR12029 6 278 7.8E-59 T 16-09-2016 Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 SMART SM00967 35 109 1.2E-13 T 16-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Spa2297_RS06155 41b4336a703b28970619674c0d12bd4f 282 SUPERFAMILY SSF75217 98 274 1.44E-40 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 Pfam PF01614 Bacterial transcriptional regulator 134 256 6.2E-30 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 Gene3D G3DSA:3.30.450.40 93 258 5.8E-61 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 Gene3D G3DSA:1.10.10.10 17 91 2.9E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 PANTHER PTHR30136 5 267 9.2E-104 T 16-09-2016 Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 SMART SM00346 19 106 4.4E-22 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 SUPERFAMILY SSF55781 76 258 4.19E-50 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 PANTHER PTHR30136:SF3 5 267 9.2E-104 T 16-09-2016 Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 SUPERFAMILY SSF46785 19 89 4.37E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26430 33aca6e2838fe32cef26df4378b4d007 267 Pfam PF09339 IclR helix-turn-helix domain 21 72 6.1E-18 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS30450 1c9838688958aeedaae611f01365c97c 191 PANTHER PTHR32097 2 191 5.0E-97 T 16-09-2016 Spa2297_RS30450 1c9838688958aeedaae611f01365c97c 191 Gene3D G3DSA:2.60.60.30 18 184 2.2E-74 T 16-09-2016 Spa2297_RS30450 1c9838688958aeedaae611f01365c97c 191 Pfam PF02342 TerD domain 3 187 4.8E-85 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS25905 d515a783d298992e39cc7cfae3851b20 342 PANTHER PTHR30336:SF2 58 333 7.3E-67 T 16-09-2016 Spa2297_RS25905 d515a783d298992e39cc7cfae3851b20 342 PANTHER PTHR30336 58 333 7.3E-67 T 16-09-2016 Spa2297_RS25905 d515a783d298992e39cc7cfae3851b20 342 Gene3D G3DSA:3.40.50.620 156 292 1.7E-28 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS25905 d515a783d298992e39cc7cfae3851b20 342 Pfam PF02698 DUF218 domain 159 306 1.3E-28 T 16-09-2016 IPR003848 Domain of unknown function DUF218 Spa2297_RS09315 c1935e8fef1611823cea5b08c67dcb7f 303 PANTHER PTHR32243:SF18 26 303 5.4E-120 T 16-09-2016 Spa2297_RS09315 c1935e8fef1611823cea5b08c67dcb7f 303 PANTHER PTHR32243 26 303 5.4E-120 T 16-09-2016 Spa2297_RS09315 c1935e8fef1611823cea5b08c67dcb7f 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 296 3.8E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS09315 c1935e8fef1611823cea5b08c67dcb7f 303 SUPERFAMILY SSF161098 31 303 2.35E-65 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS09315 c1935e8fef1611823cea5b08c67dcb7f 303 Gene3D G3DSA:1.10.3720.10 26 290 7.9E-63 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-73 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 16-09-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 Gene3D G3DSA:3.40.50.450 1 213 1.9E-73 T 16-09-2016 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PIRSF PIRSF000532 1 340 3.6E-114 T 16-09-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.114 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 6.1E-142 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 SUPERFAMILY SSF53784 1 332 4.19E-121 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 Pfam PF00365 Phosphofructokinase 2 297 3.3E-99 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS22940 ce50204ee7709d767470acc1e038ad54 341 PANTHER PTHR13697 1 335 8.8E-139 T 16-09-2016 Spa2297_RS06385 fef30a716bb5986e27825a484bd9b12d 497 PANTHER PTHR42307 1 497 2.4E-278 T 16-09-2016 Spa2297_RS06385 fef30a716bb5986e27825a484bd9b12d 497 Pfam PF03136 Pup-ligase protein 1 451 8.6E-192 T 16-09-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS06385 fef30a716bb5986e27825a484bd9b12d 497 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 1 484 6.7E-244 T 16-09-2016 IPR022366 Pup deamidase GO:0008233|GO:0016811 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.-|UniPathway: UPA00997 Spa2297_RS06385 fef30a716bb5986e27825a484bd9b12d 497 PIRSF PIRSF018077 4 494 1.4E-219 T 16-09-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS06385 fef30a716bb5986e27825a484bd9b12d 497 PANTHER PTHR42307:SF2 1 497 2.4E-278 T 16-09-2016 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 SUPERFAMILY SSF69593 11 223 2.09E-48 T 16-09-2016 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 Pfam PF01553 Acyltransferase 17 147 1.2E-20 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 PANTHER PTHR10434 1 263 3.0E-105 T 16-09-2016 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 PANTHER PTHR10434:SF21 1 263 3.0E-105 T 16-09-2016 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 SMART SM00563 29 150 1.1E-33 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS08720 06631887cb93996b1d91a20e241b10a3 266 Gene3D G3DSA:3.40.1130.10 13 203 6.6E-30 T 16-09-2016 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.2E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 SUPERFAMILY SSF52172 5 134 9.39E-38 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 PANTHER PTHR26402 5 211 6.7E-91 T 16-09-2016 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 Pfam PF00072 Response regulator receiver domain 7 118 1.6E-30 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 Gene3D G3DSA:1.10.10.10 152 211 5.9E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 SUPERFAMILY SSF46894 147 212 1.97E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 SMART SM00448 5 118 3.4E-34 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.2E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.2E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.2E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 Gene3D G3DSA:3.40.50.2300 4 151 3.2E-43 T 16-09-2016 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 SMART SM00421 149 206 1.2E-28 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS07150 b3550f306f06e9d9bce19fd1b3fd2d77 213 PANTHER PTHR26402:SF151 5 211 6.7E-91 T 16-09-2016 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 PANTHER PTHR10138 2 250 6.4E-57 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 PANTHER PTHR10138:SF0 2 250 6.4E-57 T 16-09-2016 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 Pfam PF03301 Tryptophan 2,3-dioxygenase 132 250 2.8E-22 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 Pfam PF03301 Tryptophan 2,3-dioxygenase 1 113 3.6E-23 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 1 250 33.764 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS02665 4ab83916a2c6280a54f36f1af35ec0bd 250 SUPERFAMILY SSF140959 1 249 4.58E-77 T 16-09-2016 Spa2297_RS07405 8e3c6c63a500b0092f9cce4c274ca461 242 PANTHER PTHR11040:SF61 6 237 7.1E-55 T 16-09-2016 Spa2297_RS07405 8e3c6c63a500b0092f9cce4c274ca461 242 PANTHER PTHR11040 6 237 7.1E-55 T 16-09-2016 Spa2297_RS07405 8e3c6c63a500b0092f9cce4c274ca461 242 Pfam PF02535 ZIP Zinc transporter 89 236 1.5E-11 T 16-09-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 PANTHER PTHR11601 6 398 2.3E-129 T 16-09-2016 Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 SUPERFAMILY SSF53383 4 397 7.83E-84 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 6.5E-160 T 16-09-2016 IPR011340 Cysteine desulfurase-related Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 Gene3D G3DSA:3.90.1150.10 262 398 4.0E-27 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 Pfam PF00266 Aminotransferase class-V 22 391 7.0E-55 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 PANTHER PTHR11601:SF22 6 398 2.3E-129 T 16-09-2016 Spa2297_RS03525 0c84f9dacd4c483f8e46be10b3649230 401 Gene3D G3DSA:3.40.640.10 31 261 1.7E-56 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 SMART SM00862 155 228 2.8E-29 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 Gene3D G3DSA:3.40.50.2300 4 124 4.7E-41 T 16-09-2016 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 Gene3D G3DSA:1.10.10.10 133 231 7.4E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 SMART SM00448 7 118 2.4E-41 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 PANTHER PTHR26402:SF602 7 231 7.7E-81 T 16-09-2016 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 228 5.6E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 PANTHER PTHR26402 7 231 7.7E-81 T 16-09-2016 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 Pfam PF00072 Response regulator receiver domain 10 118 1.6E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03220 a237471b8d233e19223666a32559efbf 233 SUPERFAMILY SSF52172 5 181 2.99E-42 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 Gene3D G3DSA:2.30.110.10 5 172 5.8E-51 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 Pfam PF01613 Flavin reductase like domain 10 171 1.4E-39 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 PANTHER PTHR30466:SF2 1 172 2.9E-82 T 16-09-2016 Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 PANTHER PTHR30466 1 172 2.9E-82 T 16-09-2016 Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 SUPERFAMILY SSF50475 2 171 2.45E-39 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14875 b7bf573899cfe3179a080fa22c5507d8 172 SMART SM00903 10 170 5.1E-51 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS22065 593cfad50044bdc76d4911333a68538a 103 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 83 1.1E-30 T 16-09-2016 IPR024020 Anti sigma-R factor, mycothiol system,RsrA Spa2297_RS22065 593cfad50044bdc76d4911333a68538a 103 Pfam PF13490 Putative zinc-finger 11 44 5.2E-8 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS22065 593cfad50044bdc76d4911333a68538a 103 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 84 1.6E-35 T 16-09-2016 IPR014295 Anti-sigma factor Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 Gene3D G3DSA:3.10.350.10 191 237 9.5E-12 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 Gene3D G3DSA:1.10.530.10 19 121 1.7E-43 T 16-09-2016 Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 Pfam PF06737 Transglycosylase-like domain 41 117 2.3E-35 T 16-09-2016 IPR010618 Transglycosylase-like Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 SUPERFAMILY SSF53955 42 119 3.56E-32 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 SMART SM00257 190 238 6.8E-5 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 SUPERFAMILY SSF54106 190 237 1.57E-6 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13450 aedfd394874b74cc1d8a2000e1092bdb 238 Pfam PF01476 LysM domain 191 237 2.1E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 SMART SM00436 125 213 1.6E-46 T 16-09-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF01131 DNA topoisomerase 149 591 1.2E-131 T 16-09-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Gene3D G3DSA:3.40.50.140 12 155 1.7E-48 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 14 662 1.1E-244 T 16-09-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PANTHER PTHR11390 11 219 4.2E-278 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 SUPERFAMILY SSF56712 12 595 5.49E-181 T 16-09-2016 IPR023405 DNA topoisomerase, type IA, core domain Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PANTHER PTHR11390:SF27 245 595 4.2E-278 T 16-09-2016 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PANTHER PTHR11390:SF27 11 219 4.2E-278 T 16-09-2016 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Gene3D G3DSA:2.70.20.10 354 500 1.5E-34 T 16-09-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Gene3D G3DSA:2.70.20.10 205 353 7.7E-27 T 16-09-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 SMART SM00493 12 125 5.1E-35 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 324 338 - T 16-09-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PANTHER PTHR11390 245 595 4.2E-278 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Gene3D G3DSA:1.10.460.10 156 203 2.8E-50 T 16-09-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Gene3D G3DSA:1.10.460.10 501 595 2.8E-50 T 16-09-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 406 422 1.0E-33 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 183 201 1.0E-33 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 517 531 1.0E-33 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 329 338 1.0E-33 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.0E-33 T 16-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 SMART SM00437 287 554 9.0E-122 T 16-09-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF13368 Topoisomerase C-terminal repeat 640 691 6.1E-8 T 16-09-2016 IPR025589 Topoisomerase C-terminal repeat Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF13368 Topoisomerase C-terminal repeat 832 884 1.6E-19 T 16-09-2016 IPR025589 Topoisomerase C-terminal repeat Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF13368 Topoisomerase C-terminal repeat 699 762 6.1E-14 T 16-09-2016 IPR025589 Topoisomerase C-terminal repeat Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF13368 Topoisomerase C-terminal repeat 769 819 2.4E-15 T 16-09-2016 IPR025589 Topoisomerase C-terminal repeat Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Pfam PF01751 Toprim domain 14 134 3.4E-27 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17995 5a1096cfe73c5f1289e2211428b9bb0a 954 Hamap MF_00952 DNA topoisomerase 1 [topA]. 12 778 56.464 T 16-09-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 PANTHER PTHR11019:SF58 49 318 3.7E-125 T 16-09-2016 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 Gene3D G3DSA:1.10.10.60 266 314 4.1E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 SMART SM00342 227 310 9.3E-30 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 Pfam PF12833 Helix-turn-helix domain 233 312 1.6E-25 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 SUPERFAMILY SSF46689 212 260 1.1E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 Pfam PF01965 DJ-1/PfpI family 5 172 5.2E-33 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 SUPERFAMILY SSF46689 264 314 3.41E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 Gene3D G3DSA:3.40.50.880 5 218 9.6E-68 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 SUPERFAMILY SSF52317 4 192 4.74E-57 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 Gene3D G3DSA:1.10.10.60 219 265 9.6E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28090 71ef8a050ef8b663b102b0ee246a21a8 319 PANTHER PTHR11019 49 318 3.7E-125 T 16-09-2016 Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 171 298 6.6E-18 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 PIRSF PIRSF009283 4 365 1.6E-110 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 PANTHER PTHR11959 17 365 6.4E-103 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 Gene3D G3DSA:3.10.180.10 172 364 4.0E-61 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 Gene3D G3DSA:3.10.180.10 13 171 3.7E-30 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 16 142 6.1E-12 T 16-09-2016 Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 SUPERFAMILY SSF54593 4 351 3.58E-73 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02915 a6ebbb02a8404b294244b04e912377cf 365 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 15 363 2.3E-108 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 PANTHER PTHR11831 1 204 2.4E-64 T 16-09-2016 IPR022801 Ribosomal protein S4/S9 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 SMART SM01390 3 91 5.0E-29 T 16-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 1.3E-60 T 16-09-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 Gene3D G3DSA:3.10.290.10 98 188 9.4E-25 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 PANTHER PTHR11831:SF4 1 204 2.4E-64 T 16-09-2016 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 Gene3D G3DSA:1.10.1050.10 2 97 3.6E-26 T 16-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 16-09-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 SUPERFAMILY SSF55174 6 204 6.54E-54 T 16-09-2016 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 SMART SM00363 92 158 4.0E-17 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 91 1.7E-15 T 16-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 29.102 T 16-09-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS05690 c4920b2f9a1d966bf533f9f9e4f74611 204 Pfam PF01479 S4 domain 92 139 4.0E-18 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 249 263 - T 16-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.8E-5 T 16-09-2016 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 491 506 3.8E-5 T 16-09-2016 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 PANTHER PTHR11552 8 509 2.6E-201 T 16-09-2016 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 Pfam PF05199 GMC oxidoreductase 361 501 9.8E-39 T 16-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 SUPERFAMILY SSF54373 285 449 1.28E-40 T 16-09-2016 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 Pfam PF00732 GMC oxidoreductase 8 291 1.0E-53 T 16-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 SUPERFAMILY SSF51905 448 509 9.33E-69 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 SUPERFAMILY SSF51905 5 283 9.33E-69 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 PANTHER PTHR11552:SF135 8 509 2.6E-201 T 16-09-2016 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 Gene3D G3DSA:3.50.50.60 180 308 3.8E-102 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 Gene3D G3DSA:3.50.50.60 442 508 3.8E-102 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20370 e7603576ec752d8c85232e23beea5b1f 510 Gene3D G3DSA:3.50.50.60 4 128 3.8E-102 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:1.10.8.280 189 300 1.8E-10 T 16-09-2016 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Pfam PF00005 ABC transporter 507 714 5.3E-10 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:1.20.1580.10 112 186 2.2E-29 T 16-09-2016 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:1.20.1580.10 301 366 2.2E-29 T 16-09-2016 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:3.40.50.300 367 480 3.8E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:3.40.50.300 491 551 4.5E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:3.40.50.300 678 791 4.5E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:3.40.50.300 14 79 3.8E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 PANTHER PTHR32282 19 795 0.0 T 16-09-2016 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 SUPERFAMILY SSF52540 499 767 4.08E-36 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 Gene3D G3DSA:1.20.1580.10 555 677 3.6E-36 T 16-09-2016 Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 SUPERFAMILY SSF52540 318 459 9.46E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 SUPERFAMILY SSF52540 23 71 9.46E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27150 7ab4be831fcfb7d746557da7eee5c0a7 796 PANTHER PTHR32282:SF10 19 795 0.0 T 16-09-2016 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 SMART SM00331 211 424 7.0E-39 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 Gene3D G3DSA:3.30.450.20 13 137 4.2E-16 T 16-09-2016 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 SUPERFAMILY SSF81606 225 422 3.53E-12 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 SUPERFAMILY SSF55785 13 130 3.66E-14 T 16-09-2016 IPR000014 PAS domain Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 PANTHER PTHR21021:SF19 187 422 7.2E-42 T 16-09-2016 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 137 2.7E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 Pfam PF08448 PAS fold 18 139 9.5E-15 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 238 422 1.1E-42 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00400 b7c8c3dc0caec286b9e3041f3e6c497c 424 PANTHER PTHR21021 187 422 7.2E-42 T 16-09-2016 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 PANTHER PTHR10429:SF0 2 213 4.6E-72 T 16-09-2016 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 201 35.529 T 16-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 SUPERFAMILY SSF50486 8 206 9.42E-61 T 16-09-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 PANTHER PTHR10429 2 213 4.6E-72 T 16-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 Gene3D G3DSA:3.10.300.10 8 208 6.1E-69 T 16-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 10 201 7.2E-54 T 16-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Spa2297_RS07105 d3d3bbd9380f7e94d8170c5026650501 213 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 198 2.1E-64 T 16-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 PANTHER PTHR11780:SF10 14 431 2.5E-221 T 16-09-2016 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 SUPERFAMILY SSF140490 335 433 8.5E-38 T 16-09-2016 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 59 230 1.1E-46 T 16-09-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 SUPERFAMILY SSF142019 19 250 3.66E-87 T 16-09-2016 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 SMART SM00928 339 384 4.2E-26 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 SUPERFAMILY SSF142984 253 334 2.88E-21 T 16-09-2016 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 352 363 - T 16-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 22 425 7.3E-192 T 16-09-2016 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 178 193 - T 16-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 341 424 2.1E-32 T 16-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 PANTHER PTHR11780 14 431 2.5E-221 T 16-09-2016 Spa2297_RS19220 33d5e44ae4d223a01da756d23f349ae6 449 Pfam PF10531 SLBB domain 255 301 3.0E-7 T 16-09-2016 IPR019554 Soluble ligand binding domain Spa2297_RS03285 b89cad40916f087aa47c9b72693d2264 299 PANTHER PTHR21310:SF14 12 286 1.8E-48 T 16-09-2016 Spa2297_RS03285 b89cad40916f087aa47c9b72693d2264 299 SUPERFAMILY SSF56112 21 270 6.12E-43 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS03285 b89cad40916f087aa47c9b72693d2264 299 PANTHER PTHR21310 12 286 1.8E-48 T 16-09-2016 Spa2297_RS03285 b89cad40916f087aa47c9b72693d2264 299 Pfam PF01636 Phosphotransferase enzyme family 39 258 8.7E-31 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS03285 b89cad40916f087aa47c9b72693d2264 299 Gene3D G3DSA:3.90.1200.10 107 269 6.3E-31 T 16-09-2016 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 Gene3D G3DSA:3.40.50.720 11 112 5.5E-12 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 PANTHER PTHR10996 1 322 1.1E-164 T 16-09-2016 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 SUPERFAMILY SSF52283 10 128 2.98E-13 T 16-09-2016 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 Gene3D G3DSA:3.40.50.720 113 288 1.2E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 PANTHER PTHR10996:SF167 1 322 1.1E-164 T 16-09-2016 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 29 311 5.0E-7 T 16-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 286 2.9E-43 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS30360 6bfd775916485c259edceea7c6860f72 326 SUPERFAMILY SSF51735 100 287 4.72E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 SUPERFAMILY SSF56235 2 246 2.03E-15 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 PANTHER PTHR11907:SF5 1 249 2.4E-141 T 16-09-2016 Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 Gene3D G3DSA:3.60.20.10 1 245 2.5E-40 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 246 2.9E-93 T 16-09-2016 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 PANTHER PTHR11907 1 249 2.4E-141 T 16-09-2016 Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 Pfam PF13522 Glutamine amidotransferase domain 71 217 9.1E-14 T 16-09-2016 Spa2297_RS29075 1ec1c348f3da42e7a113fb2bc42d06a3 265 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 246 41.99 T 16-09-2016 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255|UniPathway: UPA01014 Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 Gene3D G3DSA:3.40.50.300 22 246 8.7E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 PANTHER PTHR24220 26 274 4.0E-172 T 16-09-2016 Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 SMART SM00382 49 242 1.0E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 PANTHER PTHR24220:SF520 26 274 4.0E-172 T 16-09-2016 Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 Pfam PF00005 ABC transporter 40 194 1.4E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 SUPERFAMILY SSF52540 31 242 5.01E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28490 379e8835cf1c710999d6a637331eadeb 315 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 Gene3D G3DSA:3.60.110.10 1 261 2.4E-72 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 SUPERFAMILY SSF56317 1 261 1.83E-69 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 Pfam PF00795 Carbon-nitrogen hydrolase 2 243 1.8E-44 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 PANTHER PTHR23088:SF27 1 262 4.0E-71 T 16-09-2016 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 PANTHER PTHR23088 1 262 4.0E-71 T 16-09-2016 Spa2297_RS05490 abd457c0fc39925a6ad243bd7f013d27 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 140 160 - T 16-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00097 Anthranilate synthase component II signature 426 440 1.3E-9 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00097 Anthranilate synthase component II signature 505 516 1.3E-9 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00097 Anthranilate synthase component II signature 590 603 1.3E-9 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 Gene3D G3DSA:3.60.120.10 99 376 3.3E-55 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 Gene3D G3DSA:3.40.50.880 426 611 1.2E-29 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PANTHER PTHR11236 58 460 6.5E-246 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 SUPERFAMILY SSF56322 63 376 4.71E-61 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 Pfam PF00425 chorismate binding enzyme 108 367 5.5E-43 T 16-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 SUPERFAMILY SSF52317 426 611 4.38E-23 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 505 516 1.6E-10 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 471 480 1.6E-10 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PRINTS PR00096 Glutamine amidotransferase superfamily signature 590 603 1.6E-10 T 16-09-2016 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 Pfam PF00117 Glutamine amidotransferase class-I 428 608 1.9E-25 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS08695 c35a0e730223890cf9db9f5a969e0579 627 PANTHER PTHR11236:SF2 58 460 6.5E-246 T 16-09-2016 Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 Pfam PF00929 Exonuclease 10 178 1.6E-17 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 SMART SM00479 7 188 1.4E-20 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 SUPERFAMILY SSF53098 4 202 2.42E-48 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 PANTHER PTHR30231:SF9 8 233 1.6E-86 T 16-09-2016 Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 PANTHER PTHR30231 8 233 1.6E-86 T 16-09-2016 Spa2297_RS25695 cdd5bc820e2a10ee52f5162b7abc9176 240 Gene3D G3DSA:3.30.420.10 4 188 1.4E-42 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS08495 6e3ce86305cefb2b79f3ef3aa4e6c7ac 94 Pfam PF02325 YGGT family 10 90 6.7E-12 T 16-09-2016 IPR003425 CCB3/YggT GO:0016020 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 SUPERFAMILY SSF89623 1 145 1.44E-35 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 PIRSF PIRSF005384 1 147 1.6E-34 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 Pfam PF02502 Ribose/Galactose Isomerase 13 141 3.2E-28 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 PANTHER PTHR30345 1 146 9.6E-78 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 PANTHER PTHR30345:SF2 1 146 9.6E-78 T 16-09-2016 Spa2297_RS04435 23a7e591ab1f15228d916b694e103e35 151 Gene3D G3DSA:3.40.1400.10 1 146 1.5E-36 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Gene3D G3DSA:3.40.192.10 73 194 1.5E-59 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PANTHER PTHR11606:SF4 11 453 5.5E-246 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 199 221 4.7E-28 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 119 133 4.7E-28 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 241 261 4.7E-28 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 377 388 4.7E-28 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 127 140 - T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 SMART SM00839 210 451 1.5E-84 T 16-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 208 451 1.0E-85 T 16-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 SUPERFAMILY SSF51735 208 452 1.35E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PIRSF PIRSF000185 27 453 1.1E-112 T 16-09-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 SUPERFAMILY SSF53223 15 202 9.28E-73 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 62 190 1.9E-48 T 16-09-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 PANTHER PTHR11606 11 453 5.5E-246 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Gene3D G3DSA:1.10.285.10 378 452 7.0E-23 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Gene3D G3DSA:1.10.285.10 14 72 9.5E-23 T 16-09-2016 Spa2297_RS19750 b4e3d7b768da0fa563737b498ee4bf74 453 Gene3D G3DSA:3.40.50.720 215 377 1.8E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 Gene3D G3DSA:1.20.5.320 439 478 9.4E-19 T 16-09-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 SUPERFAMILY SSF48179 179 473 2.38E-115 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 SUPERFAMILY SSF51735 5 175 6.51E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 470 2.3E-200 T 16-09-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 176 7.6E-48 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 Gene3D G3DSA:1.10.1040.10 183 437 1.5E-102 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 181 470 2.1E-119 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PANTHER PTHR11811 1 479 1.4E-273 T 16-09-2016 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 Gene3D G3DSA:3.40.50.720 2 182 8.8E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PANTHER PTHR11811:SF25 1 479 1.4E-273 T 16-09-2016 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 256 268 - T 16-09-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 252 279 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 170 198 1.6E-79 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 PIRSF PIRSF000109 1 479 7.2E-196 T 16-09-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS28825 6a3b964bd3405734c6fbac4d76ad9b52 479 SMART SM01350 181 471 2.4E-198 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS12110 9ef38eed93356da2f54a1001adf8f21d 379 PANTHER PTHR10264:SF46 119 334 1.9E-70 T 16-09-2016 Spa2297_RS12110 9ef38eed93356da2f54a1001adf8f21d 379 Pfam PF01145 SPFH domain / Band 7 family 170 330 2.2E-13 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS12110 9ef38eed93356da2f54a1001adf8f21d 379 SMART SM00244 163 319 0.0062 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS12110 9ef38eed93356da2f54a1001adf8f21d 379 SUPERFAMILY SSF117892 201 322 4.71E-7 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS12110 9ef38eed93356da2f54a1001adf8f21d 379 PANTHER PTHR10264 119 334 1.9E-70 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 SUPERFAMILY SSF56014 276 360 7.19E-12 T 16-09-2016 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 PANTHER PTHR30454 3 375 3.5E-204 T 16-09-2016 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 SUPERFAMILY SSF51717 46 220 9.42E-9 T 16-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 2.2E-130 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 Gene3D G3DSA:3.20.20.70 53 189 5.4E-4 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 PIRSF PIRSF004640 12 374 2.9E-146 T 16-09-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.488 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS28190 19db58f051ac0345f214134faa168822 384 Pfam PF04551 GcpE protein 23 362 1.3E-134 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:3.40.50.300 726 750 1.3E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:3.40.50.300 519 691 1.3E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 232 364 1.0E-10 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:1.10.8.60 751 833 1.4E-30 T 16-09-2016 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:1.10.8.60 375 453 1.1E-33 T 16-09-2016 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:1.10.1780.10 36 161 7.5E-25 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PANTHER PTHR11638 24 842 0.0 T 16-09-2016 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PANTHER PTHR11638:SF108 24 842 0.0 T 16-09-2016 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 743 823 2.0E-25 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SUPERFAMILY SSF52540 514 831 7.31E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 599 617 - T 16-09-2016 IPR028299 ClpA/B, conserved site 2 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 614 632 4.5E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 643 661 4.5E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 676 690 4.5E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 569 587 4.5E-41 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:3.40.50.300 188 372 1.7E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 325 337 - T 16-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF02151 UvrB/uvrC motif 446 480 2.8E-8 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 46 95 1.7E-8 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 124 164 1.5E-9 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SUPERFAMILY SSF52540 188 475 4.73E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Pfam PF07724 AAA domain (Cdc48 subfamily) 564 737 1.9E-52 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 Gene3D G3DSA:4.10.860.10 454 482 3.6E-4 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SMART SM00382 227 373 2.8E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SMART SM00382 565 723 3.5E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SMART SM01086 743 832 5.5E-37 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS26730 db37a449c84362214be24b99f27b43d5 842 SUPERFAMILY SSF81923 36 157 1.02E-13 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 Pfam PF09339 IclR helix-turn-helix domain 14 64 2.5E-13 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 SMART SM00346 12 102 2.9E-20 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 SUPERFAMILY SSF46785 12 84 2.28E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 Gene3D G3DSA:3.30.450.40 87 251 1.9E-52 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 PANTHER PTHR30136:SF12 10 253 4.0E-148 T 16-09-2016 Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 SUPERFAMILY SSF55781 79 252 3.2E-47 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 PANTHER PTHR30136 10 253 4.0E-148 T 16-09-2016 Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 Gene3D G3DSA:1.10.10.10 11 75 2.5E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07480 0943600bbec2a2acb76d469fbbed3a64 257 Pfam PF01614 Bacterial transcriptional regulator 134 246 3.6E-28 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 Gene3D G3DSA:1.10.260.40 10 59 1.2E-24 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 SMART SM00354 10 80 2.7E-23 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 SUPERFAMILY SSF47413 10 67 4.58E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 Gene3D G3DSA:3.40.50.2300 60 185 3.9E-12 T 16-09-2016 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 PANTHER PTHR30146 9 320 2.8E-70 T 16-09-2016 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 3.7E-18 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 6.6E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 6.6E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 Pfam PF13377 Periplasmic binding protein-like domain 180 340 6.7E-23 T 16-09-2016 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 Gene3D G3DSA:3.40.50.2300 186 317 2.2E-27 T 16-09-2016 Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 SUPERFAMILY SSF53822 117 339 1.09E-33 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS31590 0aa3be8b4e2034952309a9ab7620297a 352 PANTHER PTHR30146:SF44 9 320 2.8E-70 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 Gene3D G3DSA:3.50.50.60 216 242 7.0E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 Gene3D G3DSA:3.50.50.60 288 433 7.0E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PANTHER PTHR23024 437 444 7.5E-39 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PANTHER PTHR23024 61 229 7.5E-39 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PANTHER PTHR23024:SF214 437 444 7.5E-39 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PANTHER PTHR23024:SF214 61 229 7.5E-39 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 SUPERFAMILY SSF51905 13 248 2.02E-21 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 SUPERFAMILY SSF51905 155 221 2.07E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 SUPERFAMILY SSF51905 287 433 2.07E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 12 355 8.6E-110 T 16-09-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 Gene3D G3DSA:3.50.50.60 75 215 3.2E-13 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 2.1E-5 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 2.1E-5 T 16-09-2016 Spa2297_RS31065 7821bc584148d7dbe618f610dc712db7 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.1E-5 T 16-09-2016 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 139 563 7.7E-211 T 16-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 PANTHER PTHR30557:SF1 1 91 0.0 T 16-09-2016 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 PANTHER PTHR30557 132 592 0.0 T 16-09-2016 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 PANTHER PTHR30557 1 91 0.0 T 16-09-2016 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 Pfam PF01964 Radical SAM ThiC family 140 560 4.5E-199 T 16-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 PANTHER PTHR30557:SF1 132 592 0.0 T 16-09-2016 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 139 566 55.888 T 16-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 Spa2297_RS16330 91e811648a6ffe4553a04680018970ca 597 Pfam PF13667 ThiC-associated domain 30 93 2.3E-21 T 16-09-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 SMART SM00382 44 252 2.6E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 Pfam PF00005 ABC transporter 36 180 3.0E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 PANTHER PTHR24220 20 238 8.3E-144 T 16-09-2016 Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 Gene3D G3DSA:3.40.50.300 9 241 1.9E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 PANTHER PTHR24220:SF522 20 238 8.3E-144 T 16-09-2016 Spa2297_RS19375 7cd804c32540db89d9e83c111569f315 324 SUPERFAMILY SSF52540 18 240 2.13E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 SMART SM00240 124 175 4.7E-12 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 Gene3D G3DSA:2.60.200.20 96 198 4.2E-23 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 108 199 2.2E-16 T 16-09-2016 IPR032030 YscD, cytoplasmic domain Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 SMART SM00382 1006 1243 8.7E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 Pfam PF01580 FtsK/SpoIIIE family 997 1120 3.0E-12 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 SUPERFAMILY SSF52540 989 1216 1.35E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 PANTHER PTHR23308 106 193 3.5E-12 T 16-09-2016 Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 SUPERFAMILY SSF49879 97 202 3.44E-24 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 Gene3D G3DSA:3.40.50.300 972 1113 1.5E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12865 48e99626f86b1449f64af997c18d092f 1333 Gene3D G3DSA:3.40.50.300 1166 1216 1.5E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11720 605fab5e0c6468e83fb3d4e9d529b82c 488 PANTHER PTHR11819:SF141 1 458 2.4E-135 T 16-09-2016 Spa2297_RS11720 605fab5e0c6468e83fb3d4e9d529b82c 488 Pfam PF00474 Sodium:solute symporter family 32 419 1.8E-39 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS11720 605fab5e0c6468e83fb3d4e9d529b82c 488 PANTHER PTHR11819 1 458 2.4E-135 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS17030 8869b548e5bf72b270e0248a4e03d6a5 396 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 185 388 4.3E-36 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS17030 8869b548e5bf72b270e0248a4e03d6a5 396 PANTHER PTHR21021 131 396 6.1E-22 T 16-09-2016 Spa2297_RS17030 8869b548e5bf72b270e0248a4e03d6a5 396 SMART SM00331 159 388 1.9E-12 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS17030 8869b548e5bf72b270e0248a4e03d6a5 396 PANTHER PTHR21021:SF19 131 396 6.1E-22 T 16-09-2016 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 Gene3D G3DSA:3.40.640.10 68 320 6.7E-78 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 SUPERFAMILY SSF53383 20 443 2.59E-116 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 Gene3D G3DSA:3.90.1150.10 321 444 7.2E-34 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 PANTHER PTHR11986 1 451 8.7E-172 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 PANTHER PTHR11986:SF23 1 451 8.7E-172 T 16-09-2016 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 Pfam PF00202 Aminotransferase class-III 34 442 2.3E-98 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS17705 bc48d0f32d9fc8b3fa9ece8ef5f64ed1 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 Pfam PF00425 chorismate binding enzyme 240 493 1.2E-85 T 16-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PANTHER PTHR11236 151 505 3.3E-125 T 16-09-2016 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 SUPERFAMILY SSF56322 8 501 1.83E-114 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PANTHER PTHR11236:SF9 151 505 3.3E-125 T 16-09-2016 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 Gene3D G3DSA:3.60.120.10 10 502 1.4E-124 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PRINTS PR00095 Anthranilate synthase component I signature 341 354 2.3E-14 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PRINTS PR00095 Anthranilate synthase component I signature 355 368 2.3E-14 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PRINTS PR00095 Anthranilate synthase component I signature 450 464 2.3E-14 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS23990 42bd176d2d1c7d30769d0539c0b9676b 508 PRINTS PR00095 Anthranilate synthase component I signature 435 449 2.3E-14 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 SUPERFAMILY SSF53254 16 214 8.17E-55 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 Gene3D G3DSA:3.40.50.1240 16 211 6.2E-58 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 PANTHER PTHR23029 2 210 1.4E-51 T 16-09-2016 Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 SMART SM00855 17 171 1.2E-23 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 18 210 1.0E-54 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 PANTHER PTHR23029:SF1 2 210 1.4E-51 T 16-09-2016 Spa2297_RS10875 66425118cde73326b853ea075fe32987 223 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 20 29 - T 16-09-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 PANTHER PTHR22916 2 372 5.3E-154 T 16-09-2016 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 PANTHER PTHR22916:SF3 2 372 5.3E-154 T 16-09-2016 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 SUPERFAMILY SSF53756 510 706 3.45E-5 T 16-09-2016 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 Pfam PF00535 Glycosyl transferase family 2 5 117 1.2E-36 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 PANTHER PTHR22916 408 508 5.3E-154 T 16-09-2016 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 PANTHER PTHR22916:SF3 408 508 5.3E-154 T 16-09-2016 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 347 707 1.2E-105 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 Gene3D G3DSA:3.90.550.10 2 201 4.1E-52 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12885 0cde0827e9599edc8ea05f8acaab03ed 750 SUPERFAMILY SSF53448 2 231 3.26E-55 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106:SF149 898 905 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 Pfam PF05729 NACHT domain 266 416 1.5E-27 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106 264 519 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106 537 747 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106:SF149 264 519 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106 973 985 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 Gene3D G3DSA:3.80.10.10 793 952 1.2E-8 T 16-09-2016 IPR032675 Leucine-rich repeat domain, L domain-like Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106:SF149 973 985 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106 898 905 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 SUPERFAMILY SSF52540 238 382 1.37E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 SUPERFAMILY SSF52058 784 944 1.28E-9 T 16-09-2016 IPR032675 Leucine-rich repeat domain, L domain-like Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 PANTHER PTHR24106:SF149 537 747 8.1E-110 T 16-09-2016 Spa2297_RS18340 aebc52f557594311ff237b565e4ee33a 1009 Gene3D G3DSA:3.40.50.300 257 292 3.3E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 Gene3D G3DSA:3.10.129.10 11 134 3.7E-44 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 127 8.6E-18 T 16-09-2016 IPR003736 Phenylacetic acid degradation-related domain Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 Pfam PF03061 Thioesterase superfamily 51 121 2.6E-11 T 16-09-2016 IPR006683 Thioesterase domain Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 PANTHER PTHR12418:SF24 11 141 1.2E-42 T 16-09-2016 Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 PANTHER PTHR12418 11 141 1.2E-42 T 16-09-2016 Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 21 132 1.3E-42 T 16-09-2016 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 KEGG: 00360+3.1.2.-|KEGG: 00362+3.1.2.-|KEGG: 00592+3.1.2.-|KEGG: 00903+3.1.2.- Spa2297_RS01385 ecd2b3094e7ea4f09f95918606ad5c77 155 SUPERFAMILY SSF54637 9 127 3.67E-29 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 SUPERFAMILY SSF55781 58 245 1.44E-47 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 PANTHER PTHR30136:SF7 1 245 1.2E-64 T 16-09-2016 Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 SMART SM00346 1 90 7.2E-25 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 Gene3D G3DSA:1.10.10.10 1 68 4.4E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 PANTHER PTHR30136 1 245 1.2E-64 T 16-09-2016 Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 Gene3D G3DSA:3.30.450.40 69 245 3.1E-52 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 Pfam PF09339 IclR helix-turn-helix domain 3 52 7.2E-15 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 Pfam PF01614 Bacterial transcriptional regulator 118 239 1.1E-31 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS05205 3210d39190314204a6275a26f8a1354b 247 SUPERFAMILY SSF46785 1 71 1.8E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01260 783d2d45bc6e273105ec20058f350fc4 309 SUPERFAMILY SSF55729 129 298 3.66E-19 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01260 783d2d45bc6e273105ec20058f350fc4 309 SUPERFAMILY SSF55729 7 123 1.44E-11 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01260 783d2d45bc6e273105ec20058f350fc4 309 Pfam PF00583 Acetyltransferase (GNAT) family 226 296 3.5E-7 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS01260 783d2d45bc6e273105ec20058f350fc4 309 Gene3D G3DSA:3.40.630.30 164 295 5.9E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01260 783d2d45bc6e273105ec20058f350fc4 309 Gene3D G3DSA:3.40.630.30 7 119 5.5E-11 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24585 2ab14151c04f6865030441869a12ff65 177 Pfam PF02342 TerD domain 6 163 2.8E-17 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS24585 2ab14151c04f6865030441869a12ff65 177 Gene3D G3DSA:2.60.60.30 7 168 7.7E-40 T 16-09-2016 Spa2297_RS24585 2ab14151c04f6865030441869a12ff65 177 PANTHER PTHR32097 5 163 4.1E-40 T 16-09-2016 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 SUPERFAMILY SSF103473 13 436 1.7E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 PANTHER PTHR23508 1 451 3.0E-215 T 16-09-2016 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 24 421 4.2E-134 T 16-09-2016 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 Gene3D G3DSA:1.20.1250.20 246 437 2.2E-23 T 16-09-2016 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 Gene3D G3DSA:1.20.1250.20 16 220 2.1E-21 T 16-09-2016 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 Pfam PF00083 Sugar (and other) transporter 20 435 1.3E-29 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS03350 f228a3f816c034bd15fa38d72056c183 460 PANTHER PTHR23508:SF1 1 451 3.0E-215 T 16-09-2016 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 SUPERFAMILY SSF55681 422 582 7.66E-93 T 16-09-2016 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 SUPERFAMILY SSF55681 118 298 7.66E-93 T 16-09-2016 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 6.7E-15 T 16-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 582 5.4E-184 T 16-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Gene3D G3DSA:3.30.1360.30 283 410 5.4E-42 T 16-09-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 SUPERFAMILY SSF55261 297 414 9.81E-34 T 16-09-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PANTHER PTHR22594:SF5 2 303 3.1E-212 T 16-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PANTHER PTHR22594:SF5 367 569 3.1E-212 T 16-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Gene3D G3DSA:3.30.930.10 411 583 3.0E-96 T 16-09-2016 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Gene3D G3DSA:3.30.930.10 136 282 3.0E-96 T 16-09-2016 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Gene3D G3DSA:2.40.50.140 4 108 4.2E-35 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Pfam PF02938 GAD domain 315 403 2.2E-19 T 16-09-2016 IPR029351 GAD domain Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 2.2E-21 T 16-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 2.2E-21 T 16-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 2.2E-21 T 16-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 2.2E-21 T 16-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 SUPERFAMILY SSF50249 4 107 1.03E-28 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PANTHER PTHR22594 2 303 3.1E-212 T 16-09-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 PANTHER PTHR22594 367 569 3.1E-212 T 16-09-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 4.6E-93 T 16-09-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16965 a0f9439737e83553d9115cfefc310d9e 587 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 561 32.865 T 16-09-2016 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 SMART SM00479 4 178 1.4E-27 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 38.132 T 16-09-2016 IPR022894 Oligoribonuclease GO:0016788 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 Gene3D G3DSA:3.30.420.10 1 177 3.8E-67 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 SUPERFAMILY SSF53098 3 177 4.4E-42 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 PANTHER PTHR11046 1 193 1.6E-137 T 16-09-2016 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 PANTHER PTHR11046:SF5 1 193 1.6E-137 T 16-09-2016 Spa2297_RS11840 3cbf473355c9990c3c3f0518037dad94 200 Pfam PF00929 Exonuclease 6 168 9.1E-26 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 Gene3D G3DSA:1.10.10.60 195 252 1.3E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 Pfam PF12833 Helix-turn-helix domain 221 300 3.0E-22 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 PANTHER PTHR11019:SF77 129 300 4.8E-82 T 16-09-2016 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 252 294 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 Gene3D G3DSA:1.10.10.60 253 301 3.6E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 PANTHER PTHR11019 129 300 4.8E-82 T 16-09-2016 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 Pfam PF12852 Cupin 2 183 3.8E-33 T 16-09-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 SUPERFAMILY SSF46689 251 301 8.06E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 SMART SM00342 215 298 1.6E-30 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 PANTHER PTHR11019 25 112 4.8E-82 T 16-09-2016 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 SUPERFAMILY SSF46689 198 248 5.82E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31930 8f111d6a064e4c6d8183511da2f5c727 304 PANTHER PTHR11019:SF77 25 112 4.8E-82 T 16-09-2016 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 16-09-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 5.6E-45 T 16-09-2016 IPR027486 Ribosomal protein S10 domain Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 16-09-2016 IPR027486 Ribosomal protein S10 domain Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 PANTHER PTHR11700 1 102 3.8E-53 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 16-09-2016 IPR027486 Ribosomal protein S10 domain Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 16-09-2016 IPR027486 Ribosomal protein S10 domain Spa2297_RS19790 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 16-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS06880 4301cbc2dcb69bf988c9e41f90edc222 145 Hamap MF_01197 Cell division protein SepF [sepF]. 1 137 19.23 T 16-09-2016 IPR023052 Cell division protein SepF GO:0090529 Spa2297_RS06880 4301cbc2dcb69bf988c9e41f90edc222 145 Pfam PF04472 Protein of unknown function (DUF552) 57 128 6.9E-24 T 16-09-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 Spa2297_RS06880 4301cbc2dcb69bf988c9e41f90edc222 145 PANTHER PTHR35798 17 144 6.9E-35 T 16-09-2016 Spa2297_RS06880 4301cbc2dcb69bf988c9e41f90edc222 145 PANTHER PTHR35798:SF1 17 144 6.9E-35 T 16-09-2016 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 Gene3D G3DSA:1.10.10.60 9 75 1.9E-22 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 SUPERFAMILY SSF48498 88 222 4.0E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 SUPERFAMILY SSF46689 18 78 1.39E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 86 176 3.8E-10 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 Gene3D G3DSA:1.10.357.10 76 222 1.9E-26 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 PANTHER PTHR30055 8 138 2.0E-28 T 16-09-2016 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 67 7.7E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30695 278ce7d9b31207366ab6cabe5777552e 237 PANTHER PTHR30055:SF36 8 138 2.0E-28 T 16-09-2016 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 Gene3D G3DSA:1.10.10.10 161 221 8.5E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 Pfam PF00072 Response regulator receiver domain 5 119 1.0E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 PANTHER PTHR26402 3 222 1.7E-90 T 16-09-2016 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 SMART SM00448 3 118 3.4E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 Gene3D G3DSA:3.40.50.2300 2 160 4.9E-37 T 16-09-2016 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 SMART SM00421 159 216 2.7E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 SUPERFAMILY SSF52172 3 129 9.25E-32 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 PANTHER PTHR26402:SF151 3 222 1.7E-90 T 16-09-2016 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 4.1E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08935 e5a84c772d6ea75c1f74f63358ab293a 227 SUPERFAMILY SSF46894 152 222 1.05E-22 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 Gene3D G3DSA:3.90.550.10 2 213 5.5E-31 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 SUPERFAMILY SSF53448 1 217 1.22E-32 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 PANTHER PTHR22916:SF3 1 388 5.6E-147 T 16-09-2016 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 PANTHER PTHR22916:SF3 404 505 5.6E-147 T 16-09-2016 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 Pfam PF00535 Glycosyl transferase family 2 5 114 2.3E-17 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 SUPERFAMILY SSF53756 480 704 4.39E-6 T 16-09-2016 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 343 705 7.7E-128 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 PANTHER PTHR22916 1 388 5.6E-147 T 16-09-2016 Spa2297_RS12890 92ba0f7f120a8b0e0406ece8778f454c 733 PANTHER PTHR22916 404 505 5.6E-147 T 16-09-2016 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 ProSitePatterns PS01155 Endonuclease III family signature. 214 243 - T 16-09-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 146 277 3.2E-22 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Gene3D G3DSA:1.10.340.30 135 234 5.0E-35 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Hamap MF_00942 Endonuclease III [nth]. 108 321 37.675 T 16-09-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 SMART SM00478 150 297 2.8E-61 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 TIGRFAM TIGR01083 nth: endonuclease III 117 306 5.3E-75 T 16-09-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 SUPERFAMILY SSF48150 117 324 4.4E-69 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 PANTHER PTHR10359 111 335 7.4E-82 T 16-09-2016 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Pfam PF00633 Helix-hairpin-helix motif 212 234 6.3E-6 T 16-09-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Gene3D G3DSA:1.10.1670.10 235 320 3.2E-33 T 16-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 SMART SM00525 298 318 1.4E-6 T 16-09-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 PANTHER PTHR10359:SF18 111 335 7.4E-82 T 16-09-2016 Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 299 315 - T 16-09-2016 IPR004035 Endonuclease III, iron-sulphur binding site Spa2297_RS17870 a2117ebccde8766a97551e39c87427da 364 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 299 315 5.1E-5 T 16-09-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 SUPERFAMILY SSF52374 4 138 1.06E-83 T 16-09-2016 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 SUPERFAMILY SSF52374 174 393 1.06E-83 T 16-09-2016 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PANTHER PTHR11946 5 571 1.6E-212 T 16-09-2016 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 SUPERFAMILY SSF47323 394 554 1.85E-33 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Pfam PF09334 tRNA synthetases class I (M) 4 406 1.1E-157 T 16-09-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 SUPERFAMILY SSF57770 139 173 2.35E-12 T 16-09-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 393 404 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 268 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PRINTS PR01041 Methionyl-tRNA synthetase signature 299 314 3.8E-28 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Gene3D G3DSA:1.10.730.10 389 554 3.3E-39 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 PANTHER PTHR11946:SF86 5 571 1.6E-212 T 16-09-2016 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 565 37.656 T 16-09-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Gene3D G3DSA:3.40.50.620 4 141 9.5E-83 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Gene3D G3DSA:3.40.50.620 181 388 9.5E-83 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 535 2.8E-149 T 16-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 Spa2297_RS16995 21affeb8136eeaeeccd375a804b5ab62 573 Gene3D G3DSA:2.20.28.20 142 173 1.2E-19 T 16-09-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 Gene3D G3DSA:1.10.10.60 8 59 6.1E-25 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.7E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.7E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 PANTHER PTHR30055 14 197 2.3E-65 T 16-09-2016 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 SUPERFAMILY SSF46689 5 86 5.99E-23 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 SUPERFAMILY SSF48498 92 196 5.84E-19 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 PANTHER PTHR30055:SF33 14 197 2.3E-65 T 16-09-2016 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.9E-23 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS06610 0bc0b80282be96f49f3594f51216a068 197 Gene3D G3DSA:1.10.357.10 60 197 3.1E-39 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS19440 03511f0c04da79427260aa1b7a8553fe 419 Pfam PF07730 Histidine kinase 208 273 1.6E-12 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS19440 03511f0c04da79427260aa1b7a8553fe 419 Pfam PF13796 Putative sensor 39 155 3.4E-28 T 16-09-2016 IPR025828 Putative sensor domain Spa2297_RS19440 03511f0c04da79427260aa1b7a8553fe 419 PANTHER PTHR24421 134 409 1.0E-185 T 16-09-2016 Spa2297_RS19440 03511f0c04da79427260aa1b7a8553fe 419 SUPERFAMILY SSF55874 283 394 1.92E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19440 03511f0c04da79427260aa1b7a8553fe 419 PANTHER PTHR24421:SF13 134 409 1.0E-185 T 16-09-2016 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Gene3D G3DSA:3.40.50.20 2 93 4.9E-32 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 411 3.0E-27 T 16-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Gene3D G3DSA:3.90.600.10 318 413 1.2E-31 T 16-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Gene3D G3DSA:3.30.470.20 179 316 2.0E-56 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 SUPERFAMILY SSF51246 316 413 1.46E-25 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 PANTHER PTHR10520 1 417 2.5E-216 T 16-09-2016 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 16-09-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 6.2E-65 T 16-09-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Gene3D G3DSA:3.30.1490.20 122 178 8.3E-17 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 SMART SM01210 318 414 1.7E-44 T 16-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 414 40.597 T 16-09-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 414 1.2E-144 T 16-09-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 SUPERFAMILY SSF56059 102 308 1.94E-55 T 16-09-2016 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 SMART SM01209 101 283 4.6E-112 T 16-09-2016 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 8.8E-29 T 16-09-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15860 2c05e5215d1c2319c892287816fd7996 417 SUPERFAMILY SSF52440 2 101 2.16E-29 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS04155 dddf009ea4c6130d73dce40165b6867d 145 SUPERFAMILY SSF103196 10 136 1.03E-37 T 16-09-2016 Spa2297_RS04155 dddf009ea4c6130d73dce40165b6867d 145 SMART SM00960 17 107 2.3E-33 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS04155 dddf009ea4c6130d73dce40165b6867d 145 Gene3D G3DSA:3.30.450.30 10 133 4.1E-31 T 16-09-2016 Spa2297_RS04155 dddf009ea4c6130d73dce40165b6867d 145 PANTHER PTHR36222 5 143 3.4E-52 T 16-09-2016 Spa2297_RS04155 dddf009ea4c6130d73dce40165b6867d 145 Pfam PF03259 Roadblock/LC7 domain 16 107 4.4E-28 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 PANTHER PTHR10799:SF576 448 600 1.1E-31 T 16-09-2016 Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 PANTHER PTHR10799:SF576 135 400 1.1E-31 T 16-09-2016 Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 Pfam PF00176 SNF2 family N-terminal domain 137 297 3.7E-8 T 16-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 SMART SM00490 490 583 2.6E-4 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 Pfam PF00271 Helicase conserved C-terminal domain 477 583 8.4E-9 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 Gene3D G3DSA:3.40.50.300 119 284 9.4E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 SMART SM00487 112 312 1.6E-10 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 PANTHER PTHR10799 448 600 1.1E-31 T 16-09-2016 Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 PANTHER PTHR10799 135 400 1.1E-31 T 16-09-2016 Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 SUPERFAMILY SSF52540 163 320 7.29E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 SUPERFAMILY SSF52540 457 586 7.29E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22550 facbc2b6f2de8e04ea68367a4c8d2f41 1068 Gene3D G3DSA:3.40.50.300 455 585 1.9E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 Gene3D G3DSA:2.130.10.10 254 379 7.5E-9 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 PANTHER PTHR13833:SF51 44 360 3.9E-70 T 16-09-2016 Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 Gene3D G3DSA:2.130.10.10 54 216 3.5E-21 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 PANTHER PTHR13833 44 360 3.9E-70 T 16-09-2016 Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 SUPERFAMILY SSF50969 257 378 1.18E-25 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS31000 7c3d73697c702c44aabb1d625d45592c 386 SUPERFAMILY SSF50969 16 228 1.18E-25 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 PANTHER PTHR12110:SF17 93 317 1.2E-83 T 16-09-2016 Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 PANTHER PTHR12110:SF17 1 72 1.2E-83 T 16-09-2016 Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 1.5E-22 T 16-09-2016 IPR011418 AP endonuclease, family 2, C-terminal Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 SUPERFAMILY SSF51658 8 316 5.89E-56 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 Gene3D G3DSA:3.20.20.150 4 315 1.8E-74 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 PANTHER PTHR12110 1 72 1.2E-83 T 16-09-2016 Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 PANTHER PTHR12110 93 317 1.2E-83 T 16-09-2016 Spa2297_RS27365 23e1b84b4abc8793df84debc3b63bdaa 332 Pfam PF01261 Xylose isomerase-like TIM barrel 22 272 2.5E-38 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS06625 7adc1f04b2b32f77e162a1551d4aab17 432 PANTHER PTHR30480:SF3 67 431 4.8E-118 T 16-09-2016 Spa2297_RS06625 7adc1f04b2b32f77e162a1551d4aab17 432 PANTHER PTHR30480 67 431 4.8E-118 T 16-09-2016 Spa2297_RS06625 7adc1f04b2b32f77e162a1551d4aab17 432 Pfam PF07075 Protein of unknown function (DUF1343) 73 431 4.4E-130 T 16-09-2016 IPR008302 Uncharacterised conserved protein UCP016719 Spa2297_RS06625 7adc1f04b2b32f77e162a1551d4aab17 432 PIRSF PIRSF016719 15 432 3.0E-154 T 16-09-2016 IPR008302 Uncharacterised conserved protein UCP016719 Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 Pfam PF00248 Aldo/keto reductase family 10 324 2.0E-50 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 Gene3D G3DSA:3.20.20.100 10 324 5.0E-58 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 PANTHER PTHR11732:SF241 10 87 8.6E-116 T 16-09-2016 Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 PANTHER PTHR11732 110 334 8.6E-116 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 PANTHER PTHR11732 10 87 8.6E-116 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 PANTHER PTHR11732:SF241 110 334 8.6E-116 T 16-09-2016 Spa2297_RS32170 29a9dc97b2ec8701285e0e7b2f50e9e8 336 SUPERFAMILY SSF51430 9 324 1.96E-63 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS08940 3719545dfbb556d1dd4381ddc25aadc4 409 PANTHER PTHR24421 52 406 2.3E-115 T 16-09-2016 Spa2297_RS08940 3719545dfbb556d1dd4381ddc25aadc4 409 Gene3D G3DSA:3.30.565.10 309 400 1.6E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08940 3719545dfbb556d1dd4381ddc25aadc4 409 PANTHER PTHR24421:SF26 52 406 2.3E-115 T 16-09-2016 Spa2297_RS08940 3719545dfbb556d1dd4381ddc25aadc4 409 SUPERFAMILY SSF55874 282 397 1.33E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08940 3719545dfbb556d1dd4381ddc25aadc4 409 Pfam PF07730 Histidine kinase 194 259 1.4E-18 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS03110 126a7159a825b779ad66363be9bb61cc 136 SUPERFAMILY SSF54427 2 105 8.78E-24 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS03110 126a7159a825b779ad66363be9bb61cc 136 Gene3D G3DSA:3.10.450.50 2 106 3.3E-17 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS03110 126a7159a825b779ad66363be9bb61cc 136 Pfam PF12680 SnoaL-like domain 2 98 1.1E-11 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PANTHER PTHR22893:SF29 408 765 5.1E-252 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Gene3D G3DSA:3.50.50.60 137 207 2.6E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Gene3D G3DSA:3.50.50.60 43 83 2.6E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Gene3D G3DSA:3.50.50.60 290 413 2.6E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 SUPERFAMILY SSF51395 420 765 7.33E-114 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PANTHER PTHR22893 408 765 5.1E-252 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 424 756 1.9E-58 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 SUPERFAMILY SSF51905 287 377 1.06E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 SUPERFAMILY SSF51905 42 191 1.06E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 170 185 8.1E-13 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 43 65 8.1E-13 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 8.1E-13 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 348 364 8.1E-13 T 16-09-2016 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Pfam PF01494 FAD binding domain 44 359 1.5E-13 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS25135 4ebd11dc796696a7b4602dfb4ff84a95 801 Gene3D G3DSA:3.20.20.70 421 762 3.2E-119 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS22240 5e2695c35c8b9c1cc2a07c38e44e1a4e 145 PANTHER PTHR12383 18 111 4.3E-18 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS22240 5e2695c35c8b9c1cc2a07c38e44e1a4e 145 Pfam PF00717 Peptidase S24-like 22 82 9.3E-11 T 16-09-2016 IPR019759 Peptidase S24/S26A/S26B Spa2297_RS22240 5e2695c35c8b9c1cc2a07c38e44e1a4e 145 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 22 105 1.5E-24 T 16-09-2016 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type Spa2297_RS22240 5e2695c35c8b9c1cc2a07c38e44e1a4e 145 Gene3D G3DSA:2.10.109.10 18 113 1.9E-17 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS22240 5e2695c35c8b9c1cc2a07c38e44e1a4e 145 SUPERFAMILY SSF51306 18 124 5.62E-22 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 PANTHER PTHR30055 30 223 6.2E-105 T 16-09-2016 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 1.2E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 1.2E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 Gene3D G3DSA:1.10.357.10 36 215 1.2E-30 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 SUPERFAMILY SSF46689 37 106 1.47E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 93 1.0E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29160 b257c3f6d9f6c1343fdac8c13e3b4778 225 PANTHER PTHR30055:SF37 30 223 6.2E-105 T 16-09-2016 Spa2297_RS23025 9cf834a7aa0be3cb330b3ea06da88f34 169 PIRSF PIRSF010260 1 165 3.5E-82 T 16-09-2016 IPR014457 Uncharacterised conserved protein UCP010260 Spa2297_RS23025 9cf834a7aa0be3cb330b3ea06da88f34 169 PANTHER PTHR34202:SF3 1 168 2.6E-104 T 16-09-2016 Spa2297_RS23025 9cf834a7aa0be3cb330b3ea06da88f34 169 Pfam PF09348 Domain of unknown function (DUF1990) 4 156 1.7E-56 T 16-09-2016 IPR018960 Domain of unknown function DUF1990 Spa2297_RS23025 9cf834a7aa0be3cb330b3ea06da88f34 169 PANTHER PTHR34202 1 168 2.6E-104 T 16-09-2016 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 16-09-2016 IPR018201 Beta-ketoacyl synthase, active site Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 Gene3D G3DSA:3.40.47.10 4 264 1.2E-66 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 SMART SM00825 Beta-ketoacyl synthase 6 414 4.5E-14 T 16-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 SUPERFAMILY SSF53901 220 416 1.04E-66 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 9.1E-34 T 16-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 Gene3D G3DSA:3.40.47.10 272 417 4.5E-53 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 SUPERFAMILY SSF53901 4 258 2.23E-65 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 PANTHER PTHR11712 3 117 1.6E-130 T 16-09-2016 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 PANTHER PTHR11712 135 416 1.6E-130 T 16-09-2016 Spa2297_RS22470 7a8c655b37a50ddf63cf163e996fa5b9 427 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 3.0E-51 T 16-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Pfam PF12826 Helix-hairpin-helix motif 324 361 1.3E-6 T 16-09-2016 Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Pfam PF10635 DisA bacterial checkpoint controller linker region 155 297 3.4E-53 T 16-09-2016 IPR018906 DNA integrity scanning, DisA, linker region Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 38 151 4.9E-21 T 16-09-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 17 371 44.064 T 16-09-2016 IPR023763 DNA integrity scanning protein, DisA Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Gene3D G3DSA:1.10.150.20 313 361 1.1E-11 T 16-09-2016 Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 SUPERFAMILY SSF143597 32 154 8.63E-25 T 16-09-2016 Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 Gene3D G3DSA:3.40.1700.10 32 154 1.3E-27 T 16-09-2016 Spa2297_RS18420 8b522f9b627db5957dcc459920f57e2c 374 SUPERFAMILY SSF47781 299 366 5.93E-12 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS28065 83df9bb3b730dfe228e47eff8d330658 577 PANTHER PTHR30047:SF2 3 575 1.4E-246 T 16-09-2016 Spa2297_RS28065 83df9bb3b730dfe228e47eff8d330658 577 ProSitePatterns PS01303 BCCT family of transporters signature. 343 352 - T 16-09-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 Spa2297_RS28065 83df9bb3b730dfe228e47eff8d330658 577 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 74 526 3.2E-160 T 16-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 Spa2297_RS28065 83df9bb3b730dfe228e47eff8d330658 577 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 36 526 3.5E-173 T 16-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 Spa2297_RS28065 83df9bb3b730dfe228e47eff8d330658 577 PANTHER PTHR30047 3 575 1.4E-246 T 16-09-2016 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:3.40.120.10 634 726 2.2E-13 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 641 740 1.1E-5 T 16-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 PANTHER PTHR22572:SF95 2 422 3.8E-167 T 16-09-2016 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF55957 744 828 3.66E-12 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:3.90.550.10 1 238 5.2E-77 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:3.30.310.50 752 828 2.4E-11 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 511 1.3E-12 T 16-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF51161 245 433 1.95E-32 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 PANTHER PTHR22572 2 422 3.8E-167 T 16-09-2016 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF53738 637 741 2.0E-12 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 301 1.7E-4 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Pfam PF00483 Nucleotidyl transferase 2 234 3.6E-54 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF53448 269 325 1.28E-80 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF53448 1 237 1.28E-80 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:3.40.120.10 552 628 1.7E-11 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:3.40.120.10 384 510 8.3E-12 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Gene3D G3DSA:2.160.10.10 242 366 4.9E-27 T 16-09-2016 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 SUPERFAMILY SSF53738 531 635 3.92E-13 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS05095 e28ef4b9f03eb195379e3d37ba3b4b1b 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 8.9E-17 T 16-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS17890 63c63fbdb9cf7f0ebf5357a30c4df1a8 162 PANTHER PTHR41553 1 156 3.0E-54 T 16-09-2016 Spa2297_RS17890 63c63fbdb9cf7f0ebf5357a30c4df1a8 162 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 16 134 7.3E-24 T 16-09-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III Spa2297_RS17890 63c63fbdb9cf7f0ebf5357a30c4df1a8 162 PANTHER PTHR41553:SF1 1 156 3.0E-54 T 16-09-2016 Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 SUPERFAMILY SSF50129 6 154 4.07E-29 T 16-09-2016 IPR011032 GroES-like Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 SMART SM00829 13 318 3.7E-11 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 SUPERFAMILY SSF51735 126 287 3.71E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 PANTHER PTHR11695 18 318 5.3E-98 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 Gene3D G3DSA:3.90.180.10 16 157 8.9E-28 T 16-09-2016 IPR011032 GroES-like Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 PANTHER PTHR11695:SF605 18 318 5.3E-98 T 16-09-2016 Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 Pfam PF00107 Zinc-binding dehydrogenase 165 283 3.0E-18 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS22275 07e2f18871d53936b92b38a8d02f7608 321 Gene3D G3DSA:3.40.50.720 158 267 7.0E-21 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 Gene3D G3DSA:2.40.50.140 1 66 2.7E-32 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 16-09-2016 IPR019844 Cold-shock conserved site Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 PRINTS PR00050 Cold shock protein signature 25 34 3.1E-18 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 PRINTS PR00050 Cold shock protein signature 4 19 3.1E-18 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 PRINTS PR00050 Cold shock protein signature 40 58 3.1E-18 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 PIRSF PIRSF002599 1 67 4.4E-26 T 16-09-2016 IPR012156 Cold shock, CspA GO:0003676 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.3E-32 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 SMART SM00357 3 67 7.2E-32 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 PANTHER PTHR11544 1 67 7.1E-42 T 16-09-2016 Spa2297_RS18910 fade798d5045ddf31c4d1bad2e654158 67 SUPERFAMILY SSF50249 1 66 1.2E-25 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS16825 386698773494a95964327d4e3d40629d 300 Gene3D G3DSA:3.90.550.10 19 212 1.9E-38 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16825 386698773494a95964327d4e3d40629d 300 Pfam PF12804 MobA-like NTP transferase domain 21 171 2.6E-30 T 16-09-2016 IPR025877 MobA-like NTP transferase Spa2297_RS16825 386698773494a95964327d4e3d40629d 300 SUPERFAMILY SSF53448 20 201 3.76E-27 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16825 386698773494a95964327d4e3d40629d 300 PANTHER PTHR19136 19 210 5.4E-19 T 16-09-2016 Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 Gene3D G3DSA:3.40.640.10 60 308 5.0E-65 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 PANTHER PTHR11986:SF75 1 427 1.4E-220 T 16-09-2016 Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 Gene3D G3DSA:3.90.1150.10 309 426 2.3E-33 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 PANTHER PTHR11986 1 427 1.4E-220 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 SUPERFAMILY SSF53383 16 425 2.42E-99 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS26755 632433f147b6aab22b732cd19e097b4f 427 Pfam PF00202 Aminotransferase class-III 24 424 4.6E-80 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS07410 a3bc9874c5b7fbe26ba3492059a69b2b 155 Gene3D G3DSA:3.30.420.180 3 125 2.5E-29 T 16-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Spa2297_RS07410 a3bc9874c5b7fbe26ba3492059a69b2b 155 Pfam PF01890 Cobalamin synthesis G C-terminus 4 123 3.5E-31 T 16-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Spa2297_RS07410 a3bc9874c5b7fbe26ba3492059a69b2b 155 SUPERFAMILY SSF159664 3 126 4.32E-31 T 16-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 Spa2297_RS07410 a3bc9874c5b7fbe26ba3492059a69b2b 155 PANTHER PTHR37477 4 132 1.4E-13 T 16-09-2016 Spa2297_RS07410 a3bc9874c5b7fbe26ba3492059a69b2b 155 PANTHER PTHR37477:SF1 4 132 1.4E-13 T 16-09-2016 Spa2297_RS25000 1d5dc85ef421960dd365056d8b9888e0 269 SUPERFAMILY SSF159713 47 244 1.57E-19 T 16-09-2016 Spa2297_RS25000 1d5dc85ef421960dd365056d8b9888e0 269 Pfam PF04016 Putative heavy-metal chelation 136 244 1.5E-11 T 16-09-2016 IPR007161 Putative heavy-metal chelation domain Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 Pfam PF07676 WD40-like Beta Propeller Repeat 343 370 3.0E-8 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 Gene3D G3DSA:2.130.10.10 262 287 4.3E-5 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 Pfam PF05787 Bacterial protein of unknown function (DUF839) 149 233 4.9E-12 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 Pfam PF05787 Bacterial protein of unknown function (DUF839) 104 145 4.6E-9 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 SUPERFAMILY SSF63825 172 207 1.78E-13 T 16-09-2016 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 SUPERFAMILY SSF63825 249 364 1.78E-13 T 16-09-2016 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 Gene3D G3DSA:2.130.10.10 312 366 3.3E-5 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS10505 76e0f571684355d37683f6cd8265bdd3 384 PANTHER PTHR35399 31 384 6.3E-27 T 16-09-2016 Spa2297_RS31310 7977550798fa417af0672abfe5ef3b40 261 Pfam PF12697 Alpha/beta hydrolase family 23 234 1.0E-21 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31310 7977550798fa417af0672abfe5ef3b40 261 PANTHER PTHR10992 4 246 8.5E-47 T 16-09-2016 Spa2297_RS31310 7977550798fa417af0672abfe5ef3b40 261 SUPERFAMILY SSF53474 3 245 1.59E-54 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31310 7977550798fa417af0672abfe5ef3b40 261 Gene3D G3DSA:3.40.50.1820 4 246 7.3E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 44 60 1.4E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 68 84 1.4E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 139 157 1.4E-12 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 Gene3D G3DSA:1.20.1260.10 9 163 7.3E-46 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PANTHER PTHR30295 2 162 4.2E-63 T 16-09-2016 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 Pfam PF00210 Ferritin-like domain 26 162 1.5E-25 T 16-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PIRSF PIRSF005900 1 167 1.5E-52 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 SUPERFAMILY SSF47240 8 162 3.33E-42 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 PANTHER PTHR30295:SF10 2 162 4.2E-63 T 16-09-2016 Spa2297_RS30660 6ea3a8b1da9414149df1b3436d2fd8ca 187 ProSitePatterns PS00818 Dps protein family signature 1. 44 60 - T 16-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 17 31 - T 16-09-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 TIGRFAM TIGR03356 BGL: beta-galactosidase 13 463 1.0E-181 T 16-09-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 SUPERFAMILY SSF51445 11 471 2.91E-160 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 Gene3D G3DSA:3.20.20.80 12 473 1.5E-159 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PANTHER PTHR10353 3 479 1.7E-201 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PANTHER PTHR10353:SF36 3 479 1.7E-201 T 16-09-2016 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 Pfam PF00232 Glycosyl hydrolase family 1 12 466 4.7E-159 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 2.6E-19 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.6E-19 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 295 309 2.6E-19 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 2.6E-19 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 2.6E-19 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS11870 6c03b0160d00c4e744214c47e24529eb 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 375 383 - T 16-09-2016 IPR018120 Glycoside hydrolase family 1, active site Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 SUPERFAMILY SSF50475 3 135 2.62E-32 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 9.4E-20 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 PANTHER PTHR35176:SF1 1 142 1.4E-57 T 16-09-2016 Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 135 6.1E-40 T 16-09-2016 IPR019920 F420-binding domain, putative Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 PANTHER PTHR35176 1 142 1.4E-57 T 16-09-2016 Spa2297_RS04140 f8a31f6ffab9f346394d10ecf0075027 142 Gene3D G3DSA:2.30.110.10 3 137 1.8E-41 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 Gene3D G3DSA:3.90.79.10 7 123 5.0E-32 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 PANTHER PTHR22769:SF37 15 135 1.3E-27 T 16-09-2016 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 PRINTS PR00502 NUDIX hydrolase family signature 43 57 5.5E-7 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 PRINTS PR00502 NUDIX hydrolase family signature 57 72 5.5E-7 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 Pfam PF00293 NUDIX domain 18 121 2.6E-17 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 SUPERFAMILY SSF55811 1 136 6.63E-31 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17390 ad832dc9f1c9e0e504a0452873cf8249 167 PANTHER PTHR22769 15 135 1.3E-27 T 16-09-2016 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 Pfam PF00294 pfkB family carbohydrate kinase 6 293 1.0E-62 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 SUPERFAMILY SSF53613 4 299 2.03E-75 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 Gene3D G3DSA:3.40.1190.20 4 299 4.1E-91 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PANTHER PTHR10584:SF184 1 296 1.2E-87 T 16-09-2016 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PANTHER PTHR10584 1 296 1.2E-87 T 16-09-2016 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PRINTS PR00990 Ribokinase signature 216 227 6.6E-33 T 16-09-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PRINTS PR00990 Ribokinase signature 35 54 6.6E-33 T 16-09-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PRINTS PR00990 Ribokinase signature 173 188 6.6E-33 T 16-09-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PRINTS PR00990 Ribokinase signature 106 119 6.6E-33 T 16-09-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 Spa2297_RS11615 c46df5ef5800edc489472aad4eddb3b4 300 PRINTS PR00990 Ribokinase signature 8 29 6.6E-33 T 16-09-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 PANTHER PTHR18964 6 306 5.5E-132 T 16-09-2016 Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 Gene3D G3DSA:3.30.420.40 5 140 5.4E-37 T 16-09-2016 Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 ProSitePatterns PS01125 ROK family signature. 138 165 - T 16-09-2016 IPR000600 ROK family Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 Pfam PF00480 ROK family 7 306 4.9E-64 T 16-09-2016 IPR000600 ROK family Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 Gene3D G3DSA:3.30.420.40 141 291 3.7E-48 T 16-09-2016 Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 PANTHER PTHR18964:SF124 6 306 5.5E-132 T 16-09-2016 Spa2297_RS03575 65fbcd76519d4c83228a382292735056 317 SUPERFAMILY SSF53067 6 308 2.64E-60 T 16-09-2016 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 PANTHER PTHR21180 166 407 2.1E-37 T 16-09-2016 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 PANTHER PTHR21180:SF32 166 407 2.1E-37 T 16-09-2016 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 SUPERFAMILY SSF47781 340 404 5.56E-25 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 Pfam PF10531 SLBB domain 259 311 8.3E-9 T 16-09-2016 IPR019554 Soluble ligand binding domain Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 Gene3D G3DSA:1.10.150.320 344 406 2.3E-17 T 16-09-2016 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 Pfam PF12836 Helix-hairpin-helix motif 346 407 6.5E-21 T 16-09-2016 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 SMART SM00278 356 375 0.34 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 SMART SM00278 386 405 110.0 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS10830 44bf7685b6d5afab3463700f0df420b4 408 Gene3D G3DSA:3.10.560.10 258 307 2.2E-5 T 16-09-2016 Spa2297_RS07920 07d4b2cac4e71b3a3581aabb73ef9ac0 366 PANTHER PTHR37958 1 366 1.1E-113 T 16-09-2016 Spa2297_RS07920 07d4b2cac4e71b3a3581aabb73ef9ac0 366 Pfam PF01699 Sodium/calcium exchanger protein 222 363 1.5E-14 T 16-09-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 Spa2297_RS07920 07d4b2cac4e71b3a3581aabb73ef9ac0 366 Pfam PF01699 Sodium/calcium exchanger protein 35 188 2.7E-13 T 16-09-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 Spa2297_RS07920 07d4b2cac4e71b3a3581aabb73ef9ac0 366 PANTHER PTHR37958:SF1 1 366 1.1E-113 T 16-09-2016 Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 Gene3D G3DSA:3.40.50.300 2 220 5.8E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 SMART SM00382 30 216 5.0E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 PANTHER PTHR24220:SF414 8 300 1.1E-147 T 16-09-2016 Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 SUPERFAMILY SSF52540 3 220 5.78E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 PANTHER PTHR24220 8 300 1.1E-147 T 16-09-2016 Spa2297_RS07770 f224bf6a89b01a98d575409539301e15 307 Pfam PF00005 ABC transporter 33 160 2.5E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS25705 316f31938dac4314049060b6fbb678a9 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 300 1.3E-24 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25705 316f31938dac4314049060b6fbb678a9 315 PANTHER PTHR30193 1 315 1.8E-140 T 16-09-2016 Spa2297_RS25705 316f31938dac4314049060b6fbb678a9 315 PANTHER PTHR30193:SF2 1 315 1.8E-140 T 16-09-2016 Spa2297_RS25705 316f31938dac4314049060b6fbb678a9 315 Gene3D G3DSA:1.10.3720.10 77 301 7.0E-62 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25705 316f31938dac4314049060b6fbb678a9 315 SUPERFAMILY SSF161098 73 298 3.14E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 SUPERFAMILY SSF51703 12 560 3.4E-189 T 16-09-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 1.1E-196 T 16-09-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 PANTHER PTHR23408:SF18 13 423 0.0 T 16-09-2016 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 Gene3D G3DSA:3.20.20.240 28 560 5.3E-212 T 16-09-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 PANTHER PTHR23408 440 563 0.0 T 16-09-2016 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 PANTHER PTHR23408:SF18 440 563 0.0 T 16-09-2016 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 1.3E-210 T 16-09-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Spa2297_RS22895 1573765e0896f7d8482bff5a1cd16d68 566 PANTHER PTHR23408 13 423 0.0 T 16-09-2016 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 Gene3D G3DSA:1.10.1660.10 19 112 1.3E-21 T 16-09-2016 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 ProSitePatterns PS00552 MerR-type HTH domain signature. 21 43 - T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 Pfam PF13411 MerR HTH family regulatory protein 18 85 1.1E-16 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 PANTHER PTHR30204 10 115 4.1E-36 T 16-09-2016 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 PANTHER PTHR30204:SF8 10 115 4.1E-36 T 16-09-2016 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 SMART SM00422 18 87 8.3E-26 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS17495 e480b84d902cb04f6a87897433066239 151 SUPERFAMILY SSF46955 18 109 4.3E-19 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 97 9.4E-8 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 Gene3D G3DSA:1.10.10.10 16 99 5.2E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 Pfam PF03704 Bacterial transcriptional activator domain 104 245 8.4E-39 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 SUPERFAMILY SSF48452 105 262 5.27E-33 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 SUPERFAMILY SSF46894 6 97 1.84E-10 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 Gene3D G3DSA:1.25.40.10 153 223 3.9E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 PANTHER PTHR35807 1 330 1.5E-94 T 16-09-2016 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 SMART SM00862 18 97 1.6E-7 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS29130 4204502dc5e1b91d421622dbd6c79954 656 SMART SM01043 104 245 2.4E-48 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 Pfam PF10400 Virulence activator alpha C-term 93 181 2.6E-22 T 16-09-2016 IPR018309 Transcription regulator PadR, C-terminal Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 SUPERFAMILY SSF46785 2 182 1.47E-40 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 4.6E-13 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 PANTHER PTHR33169 1 195 1.1E-75 T 16-09-2016 Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 Gene3D G3DSA:1.10.10.10 1 86 1.3E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03105 d7d8d6bcbed1f402a82160d4ec0562a7 195 PANTHER PTHR33169:SF4 1 195 1.1E-75 T 16-09-2016 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 16-09-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 SUPERFAMILY SSF52540 58 403 1.91E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 SMART SM00382 114 334 2.8E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 5.5E-15 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 52.463 T 16-09-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 SUPERFAMILY SSF57716 11 46 1.37E-11 T 16-09-2016 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Gene3D G3DSA:1.10.8.60 317 416 5.3E-35 T 16-09-2016 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 413 1.8E-197 T 16-09-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 SMART SM00994 10 49 1.1E-23 T 16-09-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 SMART SM01086 318 412 4.7E-28 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Gene3D G3DSA:3.40.50.300 295 312 1.4E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Gene3D G3DSA:3.40.50.300 62 256 1.4E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 PANTHER PTHR11262 5 421 9.0E-243 T 16-09-2016 Spa2297_RS11065 6125bd2b009ad042f52a04e1ed4a87f3 428 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 312 4.7E-51 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 SUPERFAMILY SSF53474 22 315 8.37E-63 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 80 96 - T 16-09-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 PANTHER PTHR23024 61 317 6.5E-103 T 16-09-2016 Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 Pfam PF07859 alpha/beta hydrolase fold 80 290 2.3E-67 T 16-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 PANTHER PTHR23024:SF128 61 317 6.5E-103 T 16-09-2016 Spa2297_RS32200 db437489a5f94829c957614ac4dab72b 318 Gene3D G3DSA:3.40.50.1820 5 316 5.0E-86 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 SUPERFAMILY SSF55874 413 532 3.14E-28 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 5.4E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 5.4E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 512 5.4E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 531 5.4E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Gene3D G3DSA:1.10.287.130 310 366 5.6E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Gene3D G3DSA:3.30.450.20 37 172 7.3E-44 T 16-09-2016 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 SUPERFAMILY SSF55785 207 312 1.19E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 SUPERFAMILY SSF103190 40 170 1.73E-34 T 16-09-2016 IPR029151 Periplasmic sensor domain-like Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PANTHER PTHR24423:SF379 192 535 6.5E-117 T 16-09-2016 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PANTHER PTHR24423:SF379 31 159 6.5E-117 T 16-09-2016 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 532 7.5E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Gene3D G3DSA:3.30.450.20 211 309 1.0E-9 T 16-09-2016 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 SMART SM00387 419 534 4.6E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Pfam PF17203 Single cache domain 3 41 171 2.3E-28 T 16-09-2016 IPR033463 Single cache domain 3 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 Gene3D G3DSA:3.30.565.10 383 534 2.0E-31 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 SUPERFAMILY SSF55890 328 389 3.27E-5 T 16-09-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PANTHER PTHR24423 192 535 6.5E-117 T 16-09-2016 Spa2297_RS22975 bc3d246adc1a72fc1f92c0ce4cc31f7b 555 PANTHER PTHR24423 31 159 6.5E-117 T 16-09-2016 Spa2297_RS01430 6c682c2b71cb7ff8835de2d6110449f2 255 PANTHER PTHR30269:SF10 1 255 4.1E-126 T 16-09-2016 Spa2297_RS01430 6c682c2b71cb7ff8835de2d6110449f2 255 Pfam PF01925 Sulfite exporter TauE/SafE 10 251 2.3E-38 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS01430 6c682c2b71cb7ff8835de2d6110449f2 255 PANTHER PTHR30269 1 255 4.1E-126 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS12720 ab34133cb32528e45eabb0ec7fe88517 321 PANTHER PTHR32243:SF40 28 320 2.0E-106 T 16-09-2016 Spa2297_RS12720 ab34133cb32528e45eabb0ec7fe88517 321 Gene3D G3DSA:1.10.3720.10 34 311 2.0E-53 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12720 ab34133cb32528e45eabb0ec7fe88517 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 314 3.9E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12720 ab34133cb32528e45eabb0ec7fe88517 321 SUPERFAMILY SSF161098 83 309 9.55E-52 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12720 ab34133cb32528e45eabb0ec7fe88517 321 PANTHER PTHR32243 28 320 2.0E-106 T 16-09-2016 Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 Pfam PF00692 dUTPase 18 147 1.1E-29 T 16-09-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 SUPERFAMILY SSF51283 6 147 1.44E-44 T 16-09-2016 IPR029054 dUTPase-like Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 Gene3D G3DSA:2.70.40.10 6 147 1.2E-51 T 16-09-2016 IPR029054 dUTPase-like Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 PANTHER PTHR11241 2 157 3.6E-49 T 16-09-2016 Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 31.434 T 16-09-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 147 1.5E-50 T 16-09-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 Spa2297_RS24860 2f333d953ce7e1e1e06ed01df40e40c4 183 PANTHER PTHR11241:SF0 2 157 3.6E-49 T 16-09-2016 Spa2297_RS03695 706daf96c13713ef5f69e81a646584e1 216 Pfam PF03713 Domain of unknown function (DUF305) 72 216 2.5E-50 T 16-09-2016 IPR005183 Domain of unknown function DUF305 Spa2297_RS03695 706daf96c13713ef5f69e81a646584e1 216 PANTHER PTHR36933 1 216 1.3E-44 T 16-09-2016 Spa2297_RS03695 706daf96c13713ef5f69e81a646584e1 216 PANTHER PTHR36933:SF1 1 216 1.3E-44 T 16-09-2016 Spa2297_RS03695 706daf96c13713ef5f69e81a646584e1 216 Gene3D G3DSA:1.20.1260.10 67 216 7.9E-55 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 Pfam PF00561 alpha/beta hydrolase fold 55 300 5.7E-25 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 SUPERFAMILY SSF53474 28 314 1.1E-50 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 2.9E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 2.9E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 92 2.9E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 PANTHER PTHR10992 3 315 3.7E-73 T 16-09-2016 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 PANTHER PTHR10992:SF107 3 315 3.7E-73 T 16-09-2016 Spa2297_RS21830 ac9184064a16eb9a0989767be3c648fe 340 Gene3D G3DSA:3.40.50.1820 26 313 2.1E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 309 3.9E-45 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 PANTHER PTHR13414 14 296 4.4E-103 T 16-09-2016 Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 SUPERFAMILY SSF160240 232 310 9.68E-7 T 16-09-2016 Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 Pfam PF01545 Cation efflux family 19 224 5.0E-34 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 Gene3D G3DSA:1.20.1510.10 17 227 1.7E-34 T 16-09-2016 IPR027469 Cation efflux protein transmembrane domain Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 Gene3D G3DSA:3.30.70.1350 231 305 2.6E-4 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS11735 81a9e50406365051fa0dda411e5317e1 324 SUPERFAMILY SSF161111 15 229 4.45E-39 T 16-09-2016 Spa2297_RS07370 f27fe5e632a9a55a44ffdfb533f202d1 412 Pfam PF01384 Phosphate transporter family 166 321 2.0E-45 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS07370 f27fe5e632a9a55a44ffdfb533f202d1 412 Pfam PF01384 Phosphate transporter family 22 160 6.8E-33 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS07370 f27fe5e632a9a55a44ffdfb533f202d1 412 PANTHER PTHR11101 1 357 3.6E-213 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS07370 f27fe5e632a9a55a44ffdfb533f202d1 412 PANTHER PTHR11101:SF54 1 357 3.6E-213 T 16-09-2016 Spa2297_RS09850 fe160d1a1debe24c23eadce7b6530523 193 PANTHER PTHR12608 11 193 4.3E-41 T 16-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 Spa2297_RS09850 fe160d1a1debe24c23eadce7b6530523 193 Pfam PF01169 Uncharacterized protein family UPF0016 10 79 2.4E-15 T 16-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 Spa2297_RS09850 fe160d1a1debe24c23eadce7b6530523 193 Pfam PF01169 Uncharacterized protein family UPF0016 110 183 1.9E-19 T 16-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 Spa2297_RS28140 113c98ecb7005683d14d533d42e9a1af 290 Pfam PF00535 Glycosyl transferase family 2 6 135 1.7E-10 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS28140 113c98ecb7005683d14d533d42e9a1af 290 PANTHER PTHR22916 5 255 2.4E-35 T 16-09-2016 Spa2297_RS28140 113c98ecb7005683d14d533d42e9a1af 290 Gene3D G3DSA:3.90.550.10 6 224 5.3E-25 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28140 113c98ecb7005683d14d533d42e9a1af 290 SUPERFAMILY SSF53448 5 244 4.31E-36 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28140 113c98ecb7005683d14d533d42e9a1af 290 PANTHER PTHR22916:SF29 5 255 2.4E-35 T 16-09-2016 Spa2297_RS25050 dc9dda294fd86f26c12e04fcf3ea4741 235 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 207 5.7E-50 T 16-09-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 Spa2297_RS25050 dc9dda294fd86f26c12e04fcf3ea4741 235 PANTHER PTHR34229 2 223 2.3E-123 T 16-09-2016 Spa2297_RS25050 dc9dda294fd86f26c12e04fcf3ea4741 235 PANTHER PTHR34229:SF2 2 223 2.3E-123 T 16-09-2016 Spa2297_RS25050 dc9dda294fd86f26c12e04fcf3ea4741 235 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 206 1.0E-83 T 16-09-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 Spa2297_RS25050 dc9dda294fd86f26c12e04fcf3ea4741 235 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 215 28.213 T 16-09-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 Spa2297_RS25845 377f1e71661027e5edecff7bc13ae7d6 164 Gene3D G3DSA:1.10.287.70 66 159 2.3E-18 T 16-09-2016 Spa2297_RS25845 377f1e71661027e5edecff7bc13ae7d6 164 SUPERFAMILY SSF81324 64 159 2.49E-20 T 16-09-2016 Spa2297_RS25845 377f1e71661027e5edecff7bc13ae7d6 164 Pfam PF07885 Ion channel 71 149 2.0E-16 T 16-09-2016 IPR013099 Potassium channel domain Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF56059 84 354 5.83E-72 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF89000 825 990 7.45E-41 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 6.1E-35 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:3.40.50.20 1 130 1.1E-44 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 PIRSF PIRSF001594 1 1124 0.0 T 16-09-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|UniPathway: UPA00138 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF02436 Conserved carboxylase domain 820 1007 8.9E-55 T 16-09-2016 IPR003379 Carboxylase, conserved domain Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF51246 334 451 2.51E-37 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:3.30.1490.20 131 201 2.3E-25 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:3.10.600.10 958 1045 1.3E-30 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF00364 Biotin-requiring enzyme 1065 1123 6.2E-14 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SMART SM00878 339 446 7.6E-56 T 16-09-2016 IPR005482 Biotin carboxylase, C-terminal Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:3.20.20.70 502 811 9.3E-129 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 PANTHER PTHR18866 1 1123 0.0 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF51569 521 828 1.32E-76 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:2.40.50.100 1049 1123 2.6E-19 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF52440 1 111 7.19E-41 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 2.5E-71 T 16-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1123 0.0 T 16-09-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|UniPathway: UPA00138 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 108 6.8E-40 T 16-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Gene3D G3DSA:3.30.470.20 205 451 2.4E-102 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 SUPERFAMILY SSF51230 1047 1123 7.46E-16 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 PANTHER PTHR18866:SF103 1 1123 0.0 T 16-09-2016 Spa2297_RS30855 17ce211c2e088211628104bc4ea63321 1124 Pfam PF00682 HMGL-like 525 794 2.8E-30 T 16-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 SUPERFAMILY SSF52540 44 250 2.74E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 SUPERFAMILY SSF52540 283 375 2.74E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 Gene3D G3DSA:3.40.50.300 17 188 8.0E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 Pfam PF00271 Helicase conserved C-terminal domain 284 363 7.9E-6 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 Pfam PF00270 DEAD/DEAH box helicase 33 178 3.0E-10 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 Gene3D G3DSA:3.40.50.300 228 376 4.9E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 PANTHER PTHR12131:SF4 317 363 1.0E-11 T 16-09-2016 Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 Pfam PF12029 Domain of unknown function (DUF3516) 374 834 2.5E-220 T 16-09-2016 IPR021904 Protein of unknown function DUF3516 Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 SMART SM00487 27 212 3.2E-18 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 SMART SM00490 277 363 1.3E-12 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS04120 24a19e6558362f19587bc9929528aabd 837 PANTHER PTHR12131 317 363 1.0E-11 T 16-09-2016 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 236 35.347 T 16-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 Gene3D G3DSA:3.40.50.620 9 208 6.9E-56 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 PANTHER PTHR23293:SF5 14 235 5.5E-83 T 16-09-2016 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 30 235 5.5E-58 T 16-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 PIRSF PIRSF000857 1 236 3.4E-90 T 16-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 49 211 1.2E-40 T 16-09-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 SUPERFAMILY SSF52402 20 197 1.68E-45 T 16-09-2016 Spa2297_RS25775 37709f81735048d913a2695a0dde525a 236 PANTHER PTHR23293 14 235 5.5E-83 T 16-09-2016 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Pfam PF02151 UvrB/uvrC motif 670 703 8.8E-7 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Pfam PF12344 Ultra-violet resistance protein B 559 600 3.1E-20 T 16-09-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 702 0.0 T 16-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:4.10.860.10 663 708 2.5E-12 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 PANTHER PTHR24029 643 708 0.0 T 16-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 PANTHER PTHR24029 8 611 0.0 T 16-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:3.30.2060.10 170 237 7.3E-11 T 16-09-2016 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SMART SM00487 18 433 6.3E-27 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SUPERFAMILY SSF52540 42 91 3.27E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SUPERFAMILY SSF52540 466 587 3.27E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 704 42.461 T 16-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Pfam PF04851 Type III restriction enzyme, res subunit 22 134 6.9E-9 T 16-09-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:3.40.50.300 15 98 5.1E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:3.40.50.300 286 346 5.1E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:3.40.50.300 396 417 5.1E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Pfam PF00271 Helicase conserved C-terminal domain 439 552 1.1E-19 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SUPERFAMILY SSF46600 665 707 3.01E-9 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SMART SM00490 467 553 2.8E-18 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 Gene3D G3DSA:3.40.50.300 426 588 5.7E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07940 39c7f0db71a2e5a3b8538794cd05c406 714 SUPERFAMILY SSF52540 13 422 5.87E-133 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19475 3e1c4d7e6c02b1000db5aad37b3b1bd5 130 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 106 18.829 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS19475 3e1c4d7e6c02b1000db5aad37b3b1bd5 130 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 101 4.5E-28 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS19475 3e1c4d7e6c02b1000db5aad37b3b1bd5 130 PANTHER PTHR11434 2 130 5.4E-76 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS19475 3e1c4d7e6c02b1000db5aad37b3b1bd5 130 PANTHER PTHR11434:SF0 2 130 5.4E-76 T 16-09-2016 Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 SUPERFAMILY SSF54593 10 167 5.1E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 PANTHER PTHR33993:SF2 1 254 1.1E-117 T 16-09-2016 Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 139 245 4.5E-6 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 121 1.2E-4 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 Gene3D G3DSA:3.10.180.10 11 125 4.4E-33 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 Gene3D G3DSA:3.10.180.10 139 250 1.1E-30 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 PANTHER PTHR33993 1 254 1.1E-117 T 16-09-2016 Spa2297_RS03655 a891234712545eaa408345f8127a19f5 254 SUPERFAMILY SSF54593 138 247 2.95E-19 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 PANTHER PTHR21021:SF19 133 183 1.1E-58 T 16-09-2016 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SUPERFAMILY SSF55781 43 167 2.32E-6 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 Gene3D G3DSA:3.30.450.20 196 285 3.3E-6 T 16-09-2016 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 PANTHER PTHR21021 133 183 1.1E-58 T 16-09-2016 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 Pfam PF13581 Histidine kinase-like ATPase domain 707 802 2.2E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SMART SM00065 311 463 0.0041 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 Gene3D G3DSA:3.30.450.40 293 462 5.3E-10 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SMART SM00331 484 692 1.0E-23 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SUPERFAMILY SSF55781 315 464 3.27E-12 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 PANTHER PTHR21021:SF19 459 701 1.1E-58 T 16-09-2016 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 510 692 3.4E-46 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 PANTHER PTHR21021 459 701 1.1E-58 T 16-09-2016 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SUPERFAMILY SSF55785 194 287 3.4E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SUPERFAMILY SSF81606 498 693 1.49E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 Pfam PF08447 PAS fold 200 283 6.5E-8 T 16-09-2016 IPR013655 PAS fold-3 GO:0005515 Spa2297_RS29955 e43524975033ced9050ec6af0c2bfb68 830 SUPERFAMILY SSF55874 734 821 7.11E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 1.9E-45 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 223 8.6E-26 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Gene3D G3DSA:2.40.110.10 122 223 3.0E-37 T 16-09-2016 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Gene3D G3DSA:1.20.140.10 224 383 9.5E-59 T 16-09-2016 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 3.1E-30 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 SUPERFAMILY SSF47203 233 383 3.06E-48 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 SUPERFAMILY SSF56645 4 246 5.5E-78 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 PANTHER PTHR10909 3 383 7.5E-239 T 16-09-2016 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 PANTHER PTHR10909:SF190 3 383 7.5E-239 T 16-09-2016 Spa2297_RS11745 b2d772dc656621c276b67f34f69fb34e 385 Gene3D G3DSA:1.10.540.10 6 120 1.1E-32 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 Gene3D G3DSA:3.40.50.720 4 162 2.4E-15 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 SUPERFAMILY SSF55347 154 309 4.45E-24 T 16-09-2016 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 PIRSF PIRSF036497 4 335 1.6E-71 T 16-09-2016 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 PANTHER PTHR21499:SF2 9 332 1.2E-42 T 16-09-2016 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 195 217 - T 16-09-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 Gene3D G3DSA:3.30.360.10 163 309 4.2E-24 T 16-09-2016 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 PANTHER PTHR21499 9 332 1.2E-42 T 16-09-2016 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 SUPERFAMILY SSF51735 8 155 3.01E-9 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 139 4.3E-5 T 16-09-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Spa2297_RS31465 b1794b13f0fd986d830ca692fd3b9e88 336 Pfam PF00742 Homoserine dehydrogenase 156 325 1.3E-26 T 16-09-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 Gene3D G3DSA:3.40.50.300 2 236 1.6E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 SUPERFAMILY SSF52540 1 239 6.65E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 SUPERFAMILY SSF54631 276 360 3.67E-7 T 16-09-2016 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 SMART SM00382 27 221 5.2E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 PANTHER PTHR24220 3 245 4.4E-143 T 16-09-2016 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 Gene3D G3DSA:3.10.580.10 276 358 4.6E-4 T 16-09-2016 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 PANTHER PTHR24220:SF350 3 245 4.4E-143 T 16-09-2016 Spa2297_RS25555 5a02334d372075672f58383e94678d68 383 Pfam PF00005 ABC transporter 19 163 7.2E-34 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 442 540 1.0E-7 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 SUPERFAMILY SSF54593 274 602 8.29E-48 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Gene3D G3DSA:3.10.180.10 275 392 8.7E-16 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 SUPERFAMILY SSF51658 2 271 5.24E-70 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 282 336 1.7E-6 T 16-09-2016 Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 PANTHER PTHR12110:SF14 1 273 2.8E-74 T 16-09-2016 Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Gene3D G3DSA:3.20.20.150 2 271 9.3E-74 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 PANTHER PTHR12110 1 273 2.8E-74 T 16-09-2016 Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Gene3D G3DSA:3.10.180.10 429 603 1.9E-34 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27675 4521e5f270082077d5d7c4e4fbd824da 611 Pfam PF01261 Xylose isomerase-like TIM barrel 18 220 1.9E-36 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 Pfam PF00294 pfkB family carbohydrate kinase 30 295 7.5E-38 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 SUPERFAMILY SSF53613 2 296 8.73E-54 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 Gene3D G3DSA:3.40.1190.20 2 308 8.1E-46 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 PANTHER PTHR10584:SF15 2 320 6.5E-136 T 16-09-2016 Spa2297_RS08900 4b1c95878431f436fcc34b6087498ad4 324 PANTHER PTHR10584 2 320 6.5E-136 T 16-09-2016 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 Gene3D G3DSA:3.40.190.10 197 286 5.1E-21 T 16-09-2016 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 423 4.2E-50 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 SUPERFAMILY SSF53850 39 493 1.86E-80 T 16-09-2016 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 PIRSF PIRSF002741 26 496 2.5E-52 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 PANTHER PTHR30290 9 491 8.0E-83 T 16-09-2016 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 Gene3D G3DSA:3.10.105.10 287 473 9.6E-26 T 16-09-2016 Spa2297_RS27605 fe8f3d7b74f4ffbe66ba1f7bd83e0078 502 Gene3D G3DSA:3.90.76.10 71 196 1.6E-18 T 16-09-2016 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 651 790 4.7E-54 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 377 478 4.7E-54 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 SUPERFAMILY SSF54665 15 162 7.59E-43 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 PANTHER PTHR11908 613 790 1.6E-267 T 16-09-2016 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 PANTHER PTHR11908:SF95 16 592 1.6E-267 T 16-09-2016 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 130 193 9.7E-41 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 301 375 9.7E-41 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 34 141 1.9E-35 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 479 625 5.4E-27 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 PANTHER PTHR11908:SF95 613 790 1.6E-267 T 16-09-2016 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 SUPERFAMILY SSF56003 133 790 2.62E-155 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 172 735 9.6E-151 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.30.365.10 194 298 1.8E-30 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 SMART SM01008 34 141 1.8E-47 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 PANTHER PTHR11908 16 592 1.6E-267 T 16-09-2016 Spa2297_RS26175 d79bd371295eafa01273679aec555177 794 Gene3D G3DSA:3.90.1170.50 14 129 1.5E-41 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 Pfam PF04545 Sigma-70, region 4 120 168 2.3E-15 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 PANTHER PTHR30173:SF17 17 175 1.2E-50 T 16-09-2016 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 SUPERFAMILY SSF88659 111 171 5.61E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 PANTHER PTHR30173 17 175 1.2E-50 T 16-09-2016 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 170 8.6E-21 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 Gene3D G3DSA:1.10.10.10 112 172 6.3E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 SUPERFAMILY SSF88946 11 104 2.47E-9 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 Pfam PF04542 Sigma-70 region 2 38 87 1.8E-5 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11180 9d1c1244755278454a71e21b94371cde 176 Gene3D G3DSA:1.10.1740.10 12 109 1.5E-8 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 Gene3D G3DSA:1.20.1640.10 135 340 1.6E-34 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 Gene3D G3DSA:1.20.1640.10 479 704 3.1E-29 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 PANTHER PTHR33406 1 728 5.3E-265 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 SUPERFAMILY SSF82866 135 334 6.02E-33 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 Pfam PF03176 MMPL family 45 369 4.6E-77 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 Pfam PF03176 MMPL family 431 698 3.5E-32 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 PANTHER PTHR33406:SF5 1 728 5.3E-265 T 16-09-2016 Spa2297_RS01115 c1cc1af82e04e69b3476033e39302bd1 739 SUPERFAMILY SSF82866 462 698 2.35E-25 T 16-09-2016 Spa2297_RS09290 c8041765f1e6ed1b75021b0f9773440e 117 Gene3D G3DSA:3.30.429.10 2 113 1.2E-23 T 16-09-2016 Spa2297_RS09290 c8041765f1e6ed1b75021b0f9773440e 117 PANTHER PTHR37950:SF1 2 117 5.3E-26 T 16-09-2016 Spa2297_RS09290 c8041765f1e6ed1b75021b0f9773440e 117 SUPERFAMILY SSF55331 2 112 2.38E-21 T 16-09-2016 IPR014347 Tautomerase/MIF superfamily Spa2297_RS09290 c8041765f1e6ed1b75021b0f9773440e 117 PANTHER PTHR37950 2 117 5.3E-26 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 Gene3D G3DSA:3.40.50.2000 425 723 3.2E-91 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 SUPERFAMILY SSF53756 4 747 2.2E-198 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 PANTHER PTHR11468:SF9 104 484 1.2E-269 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 PIRSF PIRSF000460 1 802 3.7E-255 T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 PANTHER PTHR11468:SF9 502 786 1.2E-269 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 Pfam PF00343 Carbohydrate phosphorylase 275 629 8.6E-15 T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 Pfam PF00343 Carbohydrate phosphorylase 125 170 3.3E-6 T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 Gene3D G3DSA:3.40.50.2000 24 424 1.6E-88 T 16-09-2016 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 719 5.7E-231 T 16-09-2016 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 607 619 - T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 PANTHER PTHR11468 502 786 1.2E-269 T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 PANTHER PTHR11468 104 484 1.2E-269 T 16-09-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 Spa2297_RS23020 8ea6529b4d305c686f8837fadfaf0ed9 872 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 3.1E-35 T 16-09-2016 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 SUPERFAMILY SSF69572 8 357 6.02E-105 T 16-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 SMART SM00450 290 387 1.1E-21 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 PANTHER PTHR10953 1 392 6.0E-277 T 16-09-2016 Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 Gene3D G3DSA:3.40.50.720 12 258 3.5E-80 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 PANTHER PTHR10953:SF153 1 392 6.0E-277 T 16-09-2016 Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 Pfam PF00899 ThiF family 21 254 1.6E-64 T 16-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 Gene3D G3DSA:3.40.250.10 274 387 1.8E-27 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS21860 31ea6c81c8d8c95fec72f2807cb1ec4d 392 Pfam PF00581 Rhodanese-like domain 290 383 2.4E-12 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS10900 f6e605dbee07d0180f53cbf176436339 379 Gene3D G3DSA:3.30.2010.10 72 158 1.1E-19 T 16-09-2016 Spa2297_RS10900 f6e605dbee07d0180f53cbf176436339 379 PANTHER PTHR22726 11 299 1.2E-40 T 16-09-2016 Spa2297_RS10900 f6e605dbee07d0180f53cbf176436339 379 Pfam PF01435 Peptidase family M48 88 272 1.1E-22 T 16-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 Gene3D G3DSA:3.30.565.10 538 681 2.8E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 SMART SM00387 571 681 8.0E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 575 678 2.3E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 PANTHER PTHR24423 739 853 1.8E-82 T 16-09-2016 Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 PANTHER PTHR24423 460 684 1.8E-82 T 16-09-2016 Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 Pfam PF08376 Nitrate and nitrite sensing 110 352 2.8E-27 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 PANTHER PTHR24423:SF523 460 684 1.8E-82 T 16-09-2016 Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 SUPERFAMILY SSF55874 557 679 5.89E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04160 bbc671b67b2b81edce990cf6dbbfdebd 855 PANTHER PTHR24423:SF523 739 853 1.8E-82 T 16-09-2016 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 2.3E-139 T 16-09-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 16-09-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 Gene3D G3DSA:3.40.50.620 4 175 2.5E-41 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 PANTHER PTHR11587:SF2 1 426 1.0E-163 T 16-09-2016 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 SUPERFAMILY SSF52402 4 185 4.44E-32 T 16-09-2016 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 472 81.359 T 16-09-2016 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 Pfam PF00764 Arginosuccinate synthase 16 394 1.4E-56 T 16-09-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 Gene3D G3DSA:3.90.1260.10 176 372 1.0E-62 T 16-09-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 16-09-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 PANTHER PTHR11587 1 426 1.0E-163 T 16-09-2016 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 Gene3D G3DSA:1.10.287.400 377 434 1.0E-28 T 16-09-2016 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS03180 80898d00b2a1f7a5742b92176fc0b220 481 SUPERFAMILY SSF69864 190 432 2.09E-75 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 Pfam PF13377 Periplasmic binding protein-like domain 173 338 2.4E-35 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.1E-19 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 Gene3D G3DSA:3.40.50.2300 176 317 5.3E-44 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 SUPERFAMILY SSF47413 4 61 4.65E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 Gene3D G3DSA:3.40.50.2300 56 175 1.0E-30 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 SMART SM00354 3 73 1.9E-29 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 PANTHER PTHR30146:SF30 2 338 6.2E-95 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 SUPERFAMILY SSF53822 63 339 2.36E-55 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 PANTHER PTHR30146 2 338 6.2E-95 T 16-09-2016 Spa2297_RS31420 9dddc68548ba09ff4e7794056e0d44ef 347 Gene3D G3DSA:1.10.260.40 4 55 1.8E-26 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 PANTHER PTHR24423 143 378 9.0E-23 T 16-09-2016 Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 Gene3D G3DSA:3.30.565.10 266 379 5.4E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 PANTHER PTHR24423:SF508 143 378 9.0E-23 T 16-09-2016 Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 372 1.1E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 SUPERFAMILY SSF55874 261 377 5.24E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 PANTHER PTHR24423 1 12 9.0E-23 T 16-09-2016 Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 SMART SM00387 262 376 2.9E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06305 8a814901e8c632bd7294b4d628630f64 539 PANTHER PTHR24423:SF508 1 12 9.0E-23 T 16-09-2016 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PANTHER PTHR11655:SF14 1 179 1.2E-86 T 16-09-2016 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PIRSF PIRSF002162 1 178 2.2E-47 T 16-09-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 Gene3D G3DSA:3.90.930.12 84 178 1.2E-37 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.3E-32 T 16-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.3E-32 T 16-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.3E-32 T 16-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 3.4E-72 T 16-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 SUPERFAMILY SSF56053 1 83 8.38E-26 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 Pfam PF00347 Ribosomal protein L6 92 165 1.6E-19 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 Pfam PF00347 Ribosomal protein L6 11 83 7.3E-20 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 37.954 T 16-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 SUPERFAMILY SSF56053 84 177 2.88E-35 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 Gene3D G3DSA:3.90.930.12 2 83 2.5E-29 T 16-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 16-09-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19870 802027796f32a5c6a55724b055d9338e 179 PANTHER PTHR11655 1 179 1.2E-86 T 16-09-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 SMART SM00650 40 214 9.0E-72 T 16-09-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 16-09-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 Gene3D G3DSA:1.10.8.100 221 284 2.8E-21 T 16-09-2016 IPR023165 rRNA adenine dimethylase-like Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 SUPERFAMILY SSF53335 24 284 6.25E-64 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 286 48.902 T 16-09-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 PANTHER PTHR11727 14 283 4.4E-83 T 16-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 Pfam PF00398 Ribosomal RNA adenine dimethylase 28 283 8.5E-44 T 16-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 Gene3D G3DSA:3.40.50.150 12 215 1.6E-66 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13695 d9acd9a1e51887aca3b271473a8333d3 286 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 283 8.7E-72 T 16-09-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 Gene3D G3DSA:3.40.50.2300 47 169 9.6E-30 T 16-09-2016 Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 Pfam PF13407 Periplasmic binding protein domain 53 297 1.6E-38 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 SUPERFAMILY SSF53822 51 323 1.57E-46 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 PANTHER PTHR30036:SF2 1 334 2.4E-125 T 16-09-2016 Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 Gene3D G3DSA:3.40.50.2300 170 298 6.5E-13 T 16-09-2016 Spa2297_RS26490 d8da62c294bea10a815706d0455dec55 334 PANTHER PTHR30036 1 334 2.4E-125 T 16-09-2016 Spa2297_RS06025 38e33ced1b384766012305df3f5263fe 323 PANTHER PTHR11732 1 318 1.1E-136 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS06025 38e33ced1b384766012305df3f5263fe 323 Gene3D G3DSA:3.20.20.100 16 308 8.1E-30 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS06025 38e33ced1b384766012305df3f5263fe 323 PANTHER PTHR11732:SF2 1 318 1.1E-136 T 16-09-2016 Spa2297_RS06025 38e33ced1b384766012305df3f5263fe 323 Pfam PF00248 Aldo/keto reductase family 49 306 7.4E-22 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS06025 38e33ced1b384766012305df3f5263fe 323 SUPERFAMILY SSF51430 44 308 1.31E-33 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS07060 5f736889f61fbcc16f0c4c1decc961ec 345 SUPERFAMILY SSF81345 15 337 1.01E-70 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS07060 5f736889f61fbcc16f0c4c1decc961ec 345 PANTHER PTHR30472:SF24 1 344 1.5E-184 T 16-09-2016 Spa2297_RS07060 5f736889f61fbcc16f0c4c1decc961ec 345 PANTHER PTHR30472 1 344 1.5E-184 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS07060 5f736889f61fbcc16f0c4c1decc961ec 345 Pfam PF01032 FecCD transport family 33 337 2.4E-82 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS07060 5f736889f61fbcc16f0c4c1decc961ec 345 Gene3D G3DSA:1.10.3470.10 20 341 2.8E-91 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS15970 26f0209424a6767a7625866a5beb7456 293 SUPERFAMILY SSF47413 7 69 7.04E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15970 26f0209424a6767a7625866a5beb7456 293 Gene3D G3DSA:1.10.260.40 3 67 6.3E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15970 26f0209424a6767a7625866a5beb7456 293 SMART SM00530 11 66 4.4E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS15970 26f0209424a6767a7625866a5beb7456 293 Pfam PF13560 Helix-turn-helix domain 8 65 8.0E-11 T 16-09-2016 Spa2297_RS15970 26f0209424a6767a7625866a5beb7456 293 Pfam PF10901 Protein of unknown function (DUF2690) 172 264 1.2E-11 T 16-09-2016 IPR021224 Protein of unknown function DUF2690 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 PANTHER PTHR30061:SF3 1 426 2.9E-144 T 16-09-2016 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 Gene3D G3DSA:3.40.190.10 158 368 5.3E-47 T 16-09-2016 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 Pfam PF01547 Bacterial extracellular solute-binding protein 57 349 6.5E-45 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 Gene3D G3DSA:3.40.190.10 30 119 2.2E-8 T 16-09-2016 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 PANTHER PTHR30061 1 426 2.9E-144 T 16-09-2016 Spa2297_RS27530 451ce332a3462ef626928753beed53ec 438 SUPERFAMILY SSF53850 39 434 6.53E-71 T 16-09-2016 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 Pfam PF01037 Lrp/AsnC ligand binding domain 76 141 1.7E-12 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 PANTHER PTHR30154 1 160 8.7E-63 T 16-09-2016 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 PANTHER PTHR30154:SF12 1 160 8.7E-63 T 16-09-2016 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 SUPERFAMILY SSF46785 4 75 3.81E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.9E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.9E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.9E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 4.7E-10 T 16-09-2016 Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 SUPERFAMILY SSF54909 66 151 1.47E-16 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 Gene3D G3DSA:3.30.70.920 59 143 1.3E-17 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 Gene3D G3DSA:1.10.10.10 5 56 2.8E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12535 557bb1ef43bea0a9a6bf5ba4fd97ffb4 163 SMART SM00344 6 112 5.5E-28 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 Pfam PF13183 4Fe-4S dicluster domain 299 407 3.5E-14 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 PANTHER PTHR11921 97 338 7.9E-207 T 16-09-2016 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 Gene3D G3DSA:1.10.1060.10 372 422 4.5E-32 T 16-09-2016 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 Gene3D G3DSA:1.10.1060.10 280 335 4.5E-32 T 16-09-2016 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 PANTHER PTHR11921:SF22 97 338 7.9E-207 T 16-09-2016 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 PANTHER PTHR11921:SF22 371 740 7.9E-207 T 16-09-2016 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 SUPERFAMILY SSF46548 375 421 1.19E-21 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 SUPERFAMILY SSF46548 287 338 1.19E-21 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 Pfam PF02754 Cysteine-rich domain 621 708 9.2E-20 T 16-09-2016 IPR004017 Cysteine-rich domain Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 Pfam PF02754 Cysteine-rich domain 478 582 4.6E-12 T 16-09-2016 IPR004017 Cysteine-rich domain Spa2297_RS17470 1005ed5c492a807aba7069ff35b9b073 760 PANTHER PTHR11921 371 740 7.9E-207 T 16-09-2016 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151:SF67 272 349 2.5E-154 T 16-09-2016 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 Gene3D G3DSA:3.40.720.10 3 293 3.1E-51 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 7 372 5.2E-63 T 16-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151:SF67 20 137 2.5E-154 T 16-09-2016 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151 171 254 2.5E-154 T 16-09-2016 IPR024873 Ectonucleotide pyrophosphatase/phosphodiesterase family Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151 272 349 2.5E-154 T 16-09-2016 IPR024873 Ectonucleotide pyrophosphatase/phosphodiesterase family Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151 20 137 2.5E-154 T 16-09-2016 IPR024873 Ectonucleotide pyrophosphatase/phosphodiesterase family Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 Gene3D G3DSA:3.30.1360.110 294 357 3.5E-8 T 16-09-2016 IPR023116 Phosphonoacetate hydrolase, insert domain GO:0047400 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 PANTHER PTHR10151:SF67 171 254 2.5E-154 T 16-09-2016 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 SUPERFAMILY SSF53649 413 457 8.22E-71 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS27405 8e8a6b0e42c7fb48ef05b22c2a8ea476 459 SUPERFAMILY SSF53649 5 358 8.22E-71 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS18050 0ff0acdf083e511bfb9f85b6806488a8 383 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 172 382 8.0E-76 T 16-09-2016 Spa2297_RS18050 0ff0acdf083e511bfb9f85b6806488a8 383 Pfam PF10979 Protein of unknown function (DUF2786) 157 196 6.9E-16 T 16-09-2016 IPR024498 Domain of unknown function DUF2786 Spa2297_RS21570 e8de3481b111ade95af286b90af61c50 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 323 3.1E-36 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21570 e8de3481b111ade95af286b90af61c50 325 PANTHER PTHR30465 1 324 1.6E-216 T 16-09-2016 Spa2297_RS21570 e8de3481b111ade95af286b90af61c50 325 Gene3D G3DSA:1.10.3720.10 97 320 1.8E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21570 e8de3481b111ade95af286b90af61c50 325 PANTHER PTHR30465:SF56 1 324 1.6E-216 T 16-09-2016 Spa2297_RS21570 e8de3481b111ade95af286b90af61c50 325 SUPERFAMILY SSF161098 99 310 8.5E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21700 8683cd558f2f22139be572cc31d814ef 174 PANTHER PTHR10509:SF18 1 174 5.9E-104 T 16-09-2016 Spa2297_RS21700 8683cd558f2f22139be572cc31d814ef 174 Pfam PF01596 O-methyltransferase 4 171 5.2E-23 T 16-09-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 Spa2297_RS21700 8683cd558f2f22139be572cc31d814ef 174 SUPERFAMILY SSF53335 3 174 5.79E-33 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21700 8683cd558f2f22139be572cc31d814ef 174 Gene3D G3DSA:3.40.50.150 1 174 4.1E-46 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21700 8683cd558f2f22139be572cc31d814ef 174 PANTHER PTHR10509 1 174 5.9E-104 T 16-09-2016 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 334 1.4E-20 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 SMART SM00382 48 247 1.7E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 Gene3D G3DSA:3.40.50.300 19 270 1.8E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 SUPERFAMILY SSF52540 20 268 1.2E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 309 2.8E-16 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 PANTHER PTHR24220:SF535 21 309 2.1E-156 T 16-09-2016 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 Pfam PF00005 ABC transporter 40 197 1.1E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS21575 0a2cdb88b756e9f675a47c069eec83e2 353 PANTHER PTHR24220 21 309 2.1E-156 T 16-09-2016 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 PANTHER PTHR10245:SF20 16 182 1.1E-32 T 16-09-2016 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 SMART SM00530 19 74 9.8E-18 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 PANTHER PTHR10245 16 182 1.1E-32 T 16-09-2016 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 Pfam PF07883 Cupin domain 123 181 5.2E-11 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 SUPERFAMILY SSF51182 70 181 1.75E-19 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 Gene3D G3DSA:2.60.120.10 96 182 4.8E-11 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 Pfam PF13560 Helix-turn-helix domain 16 74 3.0E-16 T 16-09-2016 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 SUPERFAMILY SSF47413 11 79 2.7E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS21475 7fa4841f995fdca40a163f2bb86a9e33 194 Gene3D G3DSA:1.10.260.40 12 85 2.3E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01920 175e2b44c5e4bb6e03bd1d63393fa3c0 215 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 172 1.2E-55 T 16-09-2016 IPR014144 DNA ligase D, 3'-phosphoesterase domain Spa2297_RS01920 175e2b44c5e4bb6e03bd1d63393fa3c0 215 Pfam PF13298 DNA polymerase Ligase (LigD) 39 150 4.0E-38 T 16-09-2016 IPR014144 DNA ligase D, 3'-phosphoesterase domain Spa2297_RS01920 175e2b44c5e4bb6e03bd1d63393fa3c0 215 PANTHER PTHR39465 2 202 1.3E-65 T 16-09-2016 Spa2297_RS22625 54d4554c229c652eac649bda59594ae3 381 PANTHER PTHR33392:SF7 1 367 9.9E-136 T 16-09-2016 Spa2297_RS22625 54d4554c229c652eac649bda59594ae3 381 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 119 275 6.9E-48 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS22625 54d4554c229c652eac649bda59594ae3 381 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 118 275 3.0E-53 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS22625 54d4554c229c652eac649bda59594ae3 381 PANTHER PTHR33392 1 367 9.9E-136 T 16-09-2016 Spa2297_RS25370 b8906254601f2710a6a8b6ee8c784761 511 PANTHER PTHR30480:SF2 10 338 6.4E-122 T 16-09-2016 Spa2297_RS25370 b8906254601f2710a6a8b6ee8c784761 511 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 39 328 2.8E-75 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS25370 b8906254601f2710a6a8b6ee8c784761 511 PANTHER PTHR30480 10 338 6.4E-122 T 16-09-2016 Spa2297_RS25370 b8906254601f2710a6a8b6ee8c784761 511 Gene3D G3DSA:3.20.20.300 18 329 2.6E-92 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS25370 b8906254601f2710a6a8b6ee8c784761 511 SUPERFAMILY SSF51445 19 329 8.84E-80 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 16-09-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 SUPERFAMILY SSF89919 2 113 3.79E-31 T 16-09-2016 IPR023799 Ribosome-binding factor A domain Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 20.566 T 16-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 1.8E-22 T 16-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 Gene3D G3DSA:3.30.300.20 3 118 5.2E-36 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 Pfam PF02033 Ribosome-binding factor A 6 110 1.3E-25 T 16-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 2.0E-41 T 16-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 Spa2297_RS24170 03438cfee129fbb03f3230f74443e09e 158 PANTHER PTHR33515 2 152 6.5E-46 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 PANTHER PTHR30346 2 311 1.2E-109 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 SUPERFAMILY SSF46785 3 112 1.25E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 Gene3D G3DSA:3.40.190.10 179 272 4.5E-26 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 Gene3D G3DSA:3.40.190.10 91 178 3.8E-18 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 9.1E-23 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 PANTHER PTHR30346:SF2 2 311 1.2E-109 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 SUPERFAMILY SSF53850 91 296 2.06E-34 T 16-09-2016 Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 Gene3D G3DSA:1.10.10.10 3 88 7.1E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20100 a47e9669a3d45824d430bce9001cf713 311 Pfam PF03466 LysR substrate binding domain 89 297 6.4E-42 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Gene3D G3DSA:2.30.120.10 417 499 1.7E-24 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218:SF2 331 752 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218 12 287 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218 331 752 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218:SF2 773 938 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218:SF2 12 287 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Pfam PF01804 Penicillin amidase 69 927 1.1E-241 T 16-09-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Gene3D G3DSA:3.60.20.10 508 714 1.4E-115 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Gene3D G3DSA:3.60.20.10 335 416 1.4E-115 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Gene3D G3DSA:3.60.20.10 758 775 1.4E-115 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PANTHER PTHR34218 773 938 0.0 T 16-09-2016 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 PIRSF PIRSF001227 27 938 1.5E-286 T 16-09-2016 IPR014395 Penicillin acylase GO:0016811 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 Gene3D G3DSA:1.10.439.10 53 230 7.0E-60 T 16-09-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 SUPERFAMILY SSF56235 323 938 7.46E-214 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13865 a11921c6a2bc7cd1e3b37bd5ee74339d 938 SUPERFAMILY SSF56235 65 259 7.46E-214 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 18 32 - T 16-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 SUPERFAMILY SSF69618 283 535 1.83E-65 T 16-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Gene3D G3DSA:3.40.1010.10 12 145 1.1E-30 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 238 3.4E-32 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Gene3D G3DSA:3.30.950.10 148 287 1.9E-29 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Gene3D G3DSA:3.40.50.10090 418 538 2.3E-34 T 16-09-2016 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Gene3D G3DSA:3.40.50.10090 288 410 1.8E-40 T 16-09-2016 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 PANTHER PTHR21091 10 235 1.3E-66 T 16-09-2016 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 PANTHER PTHR21091:SF128 10 235 1.3E-66 T 16-09-2016 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 Pfam PF02602 Uroporphyrinogen-III synthase HemD 297 524 2.5E-63 T 16-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18595 20694b5d45db226d4f45043de96108bc 565 SUPERFAMILY SSF53790 9 286 2.75E-42 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 Gene3D G3DSA:3.20.20.70 6 309 9.1E-83 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 16-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 SMART SM01130 6 307 1.7E-81 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PANTHER PTHR12128 7 309 5.2E-65 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 2.6E-9 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 2.6E-9 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 2.6E-9 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 2.6E-9 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 PIRSF PIRSF001365 4 309 6.2E-73 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 SUPERFAMILY SSF51569 4 309 5.97E-75 T 16-09-2016 Spa2297_RS01485 4de4acd9eecf99d03a276eb56ecca00e 309 Pfam PF00701 Dihydrodipicolinate synthetase family 7 303 1.3E-45 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 PANTHER PTHR11558:SF26 296 472 2.3E-53 T 16-09-2016 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 PANTHER PTHR11558 296 472 2.3E-53 T 16-09-2016 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 SUPERFAMILY SSF103473 14 234 7.98E-8 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 328 341 - T 16-09-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 253 547 19.524 T 16-09-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 SUPERFAMILY SSF53335 255 473 8.91E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 Pfam PF01564 Spermine/spermidine synthase 265 467 2.2E-27 T 16-09-2016 Spa2297_RS17555 d077502b7019aeb736ff6388242e5bc3 551 Gene3D G3DSA:3.40.50.150 307 515 2.1E-53 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 Gene3D G3DSA:3.30.930.10 33 222 1.1E-50 T 16-09-2016 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 PANTHER PTHR12835 14 285 4.4E-55 T 16-09-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 Pfam PF02237 Biotin protein ligase C terminal domain 236 283 4.9E-9 T 16-09-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 45 283 1.2E-36 T 16-09-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 171 1.6E-7 T 16-09-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 SUPERFAMILY SSF55681 32 222 9.94E-42 T 16-09-2016 Spa2297_RS20855 edfb5ea60933d4361f685f28c6ab10ac 287 Gene3D G3DSA:2.30.30.100 246 281 8.7E-4 T 16-09-2016 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 Gene3D G3DSA:3.40.1060.10 156 289 4.0E-34 T 16-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 Gene3D G3DSA:3.30.499.10 330 466 3.1E-55 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 Pfam PF00330 Aconitase family (aconitate hydratase) 10 458 1.9E-144 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 287 301 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 83 96 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 196 209 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 344 355 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 400 413 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 120 133 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 109 117 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 134 149 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PRINTS PR00415 Aconitase family signature 210 223 7.3E-44 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 SUPERFAMILY SSF53732 4 466 5.36E-159 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 4 467 54.925 T 16-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PANTHER PTHR11670 1 308 2.2E-216 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PANTHER PTHR11670 328 461 2.2E-216 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 Gene3D G3DSA:3.30.499.10 29 155 1.0E-23 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PANTHER PTHR11670:SF38 1 308 2.2E-216 T 16-09-2016 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 PANTHER PTHR11670:SF38 328 461 2.2E-216 T 16-09-2016 Spa2297_RS02895 7d42a1df5dc271faef456ab70fa9c358 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 5 460 2.6E-203 T 16-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 Pfam PF04234 CopC domain 33 127 5.1E-24 T 16-09-2016 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 Pfam PF05425 Copper resistance protein D 340 417 3.4E-18 T 16-09-2016 IPR008457 Copper resistance protein D GO:0016021 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 PANTHER PTHR34820:SF2 8 415 3.7E-257 T 16-09-2016 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 PANTHER PTHR34820:SF2 529 694 3.7E-257 T 16-09-2016 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 Gene3D G3DSA:2.60.40.1220 32 128 5.3E-28 T 16-09-2016 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 PANTHER PTHR34820 8 415 3.7E-257 T 16-09-2016 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 PANTHER PTHR34820 529 694 3.7E-257 T 16-09-2016 Spa2297_RS16200 49133c46dcba9f1f4a5f40b7466aab84 694 SUPERFAMILY SSF81296 32 128 5.25E-23 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS24025 36e582df7858bdd9f54d1f1a20025e20 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 257 5.8E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24025 36e582df7858bdd9f54d1f1a20025e20 266 PANTHER PTHR30222:SF6 18 263 9.1E-52 T 16-09-2016 Spa2297_RS24025 36e582df7858bdd9f54d1f1a20025e20 266 SUPERFAMILY SSF161098 5 254 5.78E-48 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24025 36e582df7858bdd9f54d1f1a20025e20 266 Gene3D G3DSA:1.10.3720.10 8 265 1.1E-49 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24025 36e582df7858bdd9f54d1f1a20025e20 266 PANTHER PTHR30222 18 263 9.1E-52 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 SUPERFAMILY SSF144083 311 372 1.44E-18 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 PANTHER PTHR21535 71 375 1.6E-60 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 Gene3D G3DSA:1.20.58.340 299 375 1.0E-24 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 SUPERFAMILY SSF143865 44 307 3.14E-64 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 Gene3D G3DSA:1.20.58.340 185 297 6.6E-36 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 Gene3D G3DSA:3.30.460.20 33 184 1.7E-40 T 16-09-2016 Spa2297_RS07980 276214b9f022ed3cf8fb2d6ddcc48420 375 Pfam PF01544 CorA-like Mg2+ transporter protein 76 370 7.5E-59 T 16-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 SUPERFAMILY SSF55186 561 720 8.89E-44 T 16-09-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 SMART SM00863 662 705 2.3E-21 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 Pfam PF01411 tRNA synthetases class II (A) 5 564 3.9E-199 T 16-09-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 Gene3D G3DSA:3.30.930.10 1 244 3.4E-98 T 16-09-2016 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 890 170.627 T 16-09-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PANTHER PTHR11777:SF9 1 890 0.0 T 16-09-2016 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 6.1E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 6.1E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 6.1E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 6.1E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 6.1E-28 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 PANTHER PTHR11777 1 890 0.0 T 16-09-2016 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 SUPERFAMILY SSF50447 461 561 4.94E-18 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 7.6E-265 T 16-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 SUPERFAMILY SSF101353 249 445 1.31E-59 T 16-09-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 3.8E-18 T 16-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 Pfam PF02272 DHHA1 domain 813 882 4.7E-12 T 16-09-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 Spa2297_RS05670 c686f126fb8df2a650755dc3d1065502 890 SUPERFAMILY SSF55681 2 248 1.99E-92 T 16-09-2016 Spa2297_RS21875 87bb2c56d97279073421ec3992e77081 934 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 632 921 3.5E-33 T 16-09-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Spa2297_RS21875 87bb2c56d97279073421ec3992e77081 934 SUPERFAMILY SSF56112 299 451 2.01E-8 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS21875 87bb2c56d97279073421ec3992e77081 934 Gene3D G3DSA:1.10.510.10 383 452 2.2E-5 T 16-09-2016 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 PANTHER PTHR33154 26 368 3.4E-271 T 16-09-2016 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 320 335 2.9E-9 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 288 303 2.9E-9 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 335 350 2.9E-9 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 Pfam PF12840 Helix-turn-helix domain 290 344 1.9E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 Gene3D G3DSA:1.10.10.10 278 363 4.9E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 SUPERFAMILY SSF46785 280 358 2.42E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 SMART SM00418 286 364 3.5E-25 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS18265 addcfdb8335a8f7ca7f6b35131dc1b17 368 PANTHER PTHR33154:SF11 26 368 3.4E-271 T 16-09-2016 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 Pfam PF00553 Cellulose binding domain 43 139 1.7E-20 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 SUPERFAMILY SSF51445 197 458 1.41E-24 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 PANTHER PTHR11177 170 455 4.2E-101 T 16-09-2016 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 Pfam PF00704 Glycosyl hydrolases family 18 247 455 5.5E-9 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 Gene3D G3DSA:2.60.40.290 41 140 3.2E-26 T 16-09-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 PANTHER PTHR11177:SF203 170 455 4.2E-101 T 16-09-2016 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 SMART SM00637 41 139 5.3E-31 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 Gene3D G3DSA:3.20.20.80 229 463 7.6E-11 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11875 13be8d91d40f6820aeed623a95ec16ec 488 SUPERFAMILY SSF49384 38 140 2.44E-23 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 5.1E-24 T 16-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 25.629 T 16-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 SUPERFAMILY SSF55200 70 154 3.53E-32 T 16-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 Gene3D G3DSA:3.30.110.10 64 156 1.6E-38 T 16-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 SUPERFAMILY SSF54364 1 63 4.84E-23 T 16-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 69 152 5.4E-34 T 16-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 Gene3D G3DSA:3.10.20.80 1 63 7.0E-28 T 16-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 155 5.8E-57 T 16-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Spa2297_RS06170 8298d0e1cdb86cdc61ab9b67643a8b1f 203 PANTHER PTHR10938 1 174 1.7E-64 T 16-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 SUPERFAMILY SSF102114 20 408 3.4E-107 T 16-09-2016 Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 Gene3D G3DSA:3.80.30.20 32 274 5.9E-35 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 367 8.6E-70 T 16-09-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 Pfam PF04055 Radical SAM superfamily 35 213 3.2E-21 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 PANTHER PTHR13932:SF5 27 409 3.9E-139 T 16-09-2016 Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 PANTHER PTHR13932 27 409 3.9E-139 T 16-09-2016 Spa2297_RS10775 3ef1d2ad2dc3c669db4f82aac3a2a996 410 SMART SM00729 29 259 8.3E-59 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 Gene3D G3DSA:3.40.50.10330 5 152 1.2E-32 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 Gene3D G3DSA:2.60.200.30 153 265 1.6E-37 T 16-09-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 Hamap MF_00361 NAD kinase [nadK]. 7 291 29.752 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 PANTHER PTHR20275 3 289 6.7E-77 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 SUPERFAMILY SSF111331 8 297 3.92E-79 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS07035 20134ba713a4861316236e388f52983a 301 Pfam PF01513 ATP-NAD kinase 56 275 7.1E-58 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 PANTHER PTHR11695:SF501 21 349 5.6E-113 T 16-09-2016 Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 Gene3D G3DSA:3.90.180.10 12 180 9.7E-44 T 16-09-2016 IPR011032 GroES-like Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 Gene3D G3DSA:3.40.50.720 181 296 2.6E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 Pfam PF00107 Zinc-binding dehydrogenase 189 311 8.8E-18 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 SUPERFAMILY SSF50129 12 187 2.59E-45 T 16-09-2016 IPR011032 GroES-like Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 PANTHER PTHR11695 21 349 5.6E-113 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 146 3.9E-25 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS06565 bd1748c5b1a5d2e142093a89a0678a9f 355 SUPERFAMILY SSF51735 157 300 4.23E-30 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 SUPERFAMILY SSF54909 61 143 1.1E-15 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 SUPERFAMILY SSF46785 1 60 1.55E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.4E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.4E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.4E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 Gene3D G3DSA:1.10.10.10 3 53 9.9E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 PANTHER PTHR30154:SF2 1 142 8.7E-51 T 16-09-2016 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 Gene3D G3DSA:3.30.70.920 54 133 3.1E-24 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 PANTHER PTHR30154 1 142 8.7E-51 T 16-09-2016 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 2.6E-15 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 SMART SM00344 1 108 8.2E-44 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS05350 de6d7a3e52a0bb6f0b416210d34481a6 146 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.4E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Gene3D G3DSA:3.30.559.10 145 386 1.6E-51 T 16-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 154 386 3.8E-51 T 16-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Gene3D G3DSA:3.40.50.970 496 865 2.3E-78 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 24 61 7.8E-12 T 16-09-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 SUPERFAMILY SSF52518 913 1122 9.81E-46 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 PANTHER PTHR23152:SF4 371 1271 0.0 T 16-09-2016 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 PANTHER PTHR23152 371 1271 0.0 T 16-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 SUPERFAMILY SSF52777 145 386 5.78E-55 T 16-09-2016 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Pfam PF02779 Transketolase, pyrimidine binding domain 923 1116 1.0E-57 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Pfam PF00676 Dehydrogenase E1 component 539 862 1.4E-55 T 16-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 417 1270 0.0 T 16-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 SMART SM00861 924 1117 3.1E-51 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Gene3D G3DSA:3.40.50.970 931 1128 2.0E-22 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 SUPERFAMILY SSF52518 454 861 4.37E-86 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1122 1270 3.6E-44 T 16-09-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Spa2297_RS22310 f2bc52087f8e7e259bff52576dcb2a90 1272 PIRSF PIRSF000157 11 1272 0.0 T 16-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 Gene3D G3DSA:3.90.180.10 9 146 1.9E-58 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 Pfam PF00107 Zinc-binding dehydrogenase 164 291 1.2E-23 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 SMART SM00829 25 338 2.0E-8 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 SUPERFAMILY SSF51735 129 305 4.38E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 SUPERFAMILY SSF50129 10 145 1.45E-43 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 Gene3D G3DSA:3.40.50.720 147 308 6.7E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 Pfam PF16884 N-terminal domain of oxidoreductase 12 118 1.6E-42 T 16-09-2016 Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 PANTHER PTHR11695:SF528 29 339 7.1E-126 T 16-09-2016 Spa2297_RS10090 5e275fc2ceab2af2189277b41056663e 340 PANTHER PTHR11695 29 339 7.1E-126 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 Gene3D G3DSA:1.10.10.10 3 81 8.1E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.3E-22 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 SUPERFAMILY SSF46785 2 86 4.75E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 PANTHER PTHR30346 1 298 7.4E-84 T 16-09-2016 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 Gene3D G3DSA:3.40.190.10 89 178 1.1E-23 T 16-09-2016 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.4E-9 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.4E-9 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.4E-9 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 SUPERFAMILY SSF53850 91 298 1.21E-33 T 16-09-2016 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 Gene3D G3DSA:3.40.190.10 179 263 8.5E-23 T 16-09-2016 Spa2297_RS32175 47169acad5ee5ff7b581099b18bba938 308 Pfam PF03466 LysR substrate binding domain 88 293 1.1E-39 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PRINTS PR00143 Citrate synthase signature 300 320 4.9E-10 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PRINTS PR00143 Citrate synthase signature 354 370 4.9E-10 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PRINTS PR00143 Citrate synthase signature 188 201 4.9E-10 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PRINTS PR00143 Citrate synthase signature 374 388 4.9E-10 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 Pfam PF12728 Helix-turn-helix domain 16 67 3.9E-9 T 16-09-2016 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 Gene3D G3DSA:1.10.580.10 81 288 2.6E-39 T 16-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 SUPERFAMILY SSF48256 77 416 2.75E-71 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PANTHER PTHR11739:SF9 2 419 7.6E-189 T 16-09-2016 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 Gene3D G3DSA:1.10.230.10 289 365 5.1E-14 T 16-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 PANTHER PTHR11739 2 419 7.6E-189 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 SUPERFAMILY SSF46955 15 66 4.03E-7 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 Pfam PF00285 Citrate synthase, C-terminal domain 81 404 2.4E-65 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS24715 55edc9f995f22fa02d1c318d1321a870 419 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 61 2.6E-8 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 358 38.046 T 16-09-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 PANTHER PTHR11075:SF9 1 358 1.9E-158 T 16-09-2016 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 PANTHER PTHR11075 1 358 1.9E-158 T 16-09-2016 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 SUPERFAMILY SSF75620 8 355 5.36E-129 T 16-09-2016 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 SMART SM00937 63 181 5.2E-56 T 16-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 Gene3D G3DSA:1.20.58.410 5 88 1.1E-16 T 16-09-2016 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 Pfam PF03462 PCRF domain 9 206 2.3E-68 T 16-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 356 6.6E-152 T 16-09-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 Pfam PF00472 RF-1 domain 214 323 1.8E-41 T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS22635 d051d2f1ab228b98f9fd2bd3e9feb5cd 358 Gene3D G3DSA:3.30.160.20 213 291 1.5E-34 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 SUPERFAMILY SSF63380 15 109 9.14E-14 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 PANTHER PTHR30157:SF1 4 241 1.4E-70 T 16-09-2016 Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 Gene3D G3DSA:2.40.30.10 16 110 3.0E-21 T 16-09-2016 Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 Gene3D G3DSA:3.40.50.80 119 241 1.9E-22 T 16-09-2016 Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 PANTHER PTHR30157 4 241 1.4E-70 T 16-09-2016 Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 Pfam PF04954 Siderophore-interacting protein 125 241 5.8E-17 T 16-09-2016 IPR007037 Siderophore-interacting protein Spa2297_RS15910 30f19b3c122d525ce8a5d37db32ff186 242 Pfam PF08021 Siderophore-interacting FAD-binding domain 54 108 1.3E-9 T 16-09-2016 IPR013113 FAD-binding 9, siderophore-interacting Spa2297_RS24855 5663fbd91e62b38a01bfc8716f12ef6d 194 PANTHER PTHR12418:SF16 61 173 1.0E-20 T 16-09-2016 Spa2297_RS24855 5663fbd91e62b38a01bfc8716f12ef6d 194 Pfam PF03061 Thioesterase superfamily 75 141 2.6E-9 T 16-09-2016 IPR006683 Thioesterase domain Spa2297_RS24855 5663fbd91e62b38a01bfc8716f12ef6d 194 Gene3D G3DSA:3.10.129.10 21 166 5.1E-43 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS24855 5663fbd91e62b38a01bfc8716f12ef6d 194 PANTHER PTHR12418 61 173 1.0E-20 T 16-09-2016 Spa2297_RS24855 5663fbd91e62b38a01bfc8716f12ef6d 194 SUPERFAMILY SSF54637 21 159 6.62E-33 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS14685 4fd4890064d2b0418a88da529091c702 847 Pfam PF13625 Helicase conserved C-terminal domain 553 675 8.3E-42 T 16-09-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PANTHER PTHR10795 172 241 6.3E-103 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 208 219 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PANTHER PTHR10795:SF421 364 645 6.3E-103 T 16-09-2016 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PANTHER PTHR10795:SF421 172 241 6.3E-103 T 16-09-2016 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PANTHER PTHR10795 364 645 6.3E-103 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 580 596 2.3E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 383 396 2.3E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 PRINTS PR00723 Subtilisin serine protease family (S8) signature 203 222 2.3E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 581 591 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 948 1013 6.4E-9 T 16-09-2016 IPR007280 Peptidase, C-terminal, archaeal/bacterial Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 Gene3D G3DSA:3.40.50.200 387 642 2.3E-66 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 Gene3D G3DSA:3.40.50.200 197 249 2.3E-66 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 Gene3D G3DSA:2.60.120.380 940 1024 7.3E-8 T 16-09-2016 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 Pfam PF00082 Subtilase family 203 626 7.9E-56 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 SUPERFAMILY SSF52743 192 223 1.22E-52 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS11170 0b5425f9aedbd86e8fb8c55ff89edda4 1098 SUPERFAMILY SSF52743 386 642 1.22E-52 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS23165 4a05ce0bb81e89def86e795b63785d12 332 SUPERFAMILY SSF161098 107 318 1.83E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23165 4a05ce0bb81e89def86e795b63785d12 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 330 8.3E-42 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23165 4a05ce0bb81e89def86e795b63785d12 332 PANTHER PTHR30465:SF56 1 331 3.4E-191 T 16-09-2016 Spa2297_RS23165 4a05ce0bb81e89def86e795b63785d12 332 PANTHER PTHR30465 1 331 3.4E-191 T 16-09-2016 Spa2297_RS23165 4a05ce0bb81e89def86e795b63785d12 332 Gene3D G3DSA:1.10.3720.10 105 327 5.7E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 PANTHER PTHR20852:SF35 2 454 7.9E-202 T 16-09-2016 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 Pfam PF00120 Glutamine synthetase, catalytic domain 121 449 1.2E-101 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 SMART SM01230 120 372 5.2E-101 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 SUPERFAMILY SSF55931 121 452 3.43E-100 T 16-09-2016 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 Gene3D G3DSA:3.30.590.10 124 441 1.3E-96 T 16-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 SUPERFAMILY SSF54368 10 119 1.83E-15 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 Gene3D G3DSA:3.10.20.70 11 123 3.1E-9 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS06220 d7ad4ab157fb7a07c79a131f56d1c2a1 454 PANTHER PTHR20852 2 454 7.9E-202 T 16-09-2016 Spa2297_RS20595 52bc5ce9405f825def70f0d8bb0b0f7a 320 SUPERFAMILY SSF53335 16 173 3.44E-11 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20595 52bc5ce9405f825def70f0d8bb0b0f7a 320 Gene3D G3DSA:3.40.50.150 45 172 8.2E-7 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20595 52bc5ce9405f825def70f0d8bb0b0f7a 320 Pfam PF13578 Methyltransferase domain 46 167 7.0E-14 T 16-09-2016 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 Gene3D G3DSA:1.10.260.40 15 74 5.2E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 SUPERFAMILY SSF47413 16 71 3.66E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 SMART SM00530 20 75 1.2E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 Pfam PF13560 Helix-turn-helix domain 17 71 1.7E-13 T 16-09-2016 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 PANTHER PTHR10245:SF7 11 274 4.8E-110 T 16-09-2016 Spa2297_RS14780 c6336fcd70d8bfe63696c0d075da148f 279 PANTHER PTHR10245 11 274 4.8E-110 T 16-09-2016 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 SUPERFAMILY SSF46785 21 116 5.6E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 Gene3D G3DSA:1.10.10.10 19 115 2.8E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PANTHER PTHR33154:SF4 17 115 2.7E-39 T 16-09-2016 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PANTHER PTHR33154 17 115 2.7E-39 T 16-09-2016 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 Pfam PF01022 Bacterial regulatory protein, arsR family 43 90 3.2E-16 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 SMART SM00418 36 116 8.9E-29 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 16-09-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 6.3E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 6.3E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 6.3E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04050 462439bc042c1e39f834a948cfba16b2 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 6.3E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 SUPERFAMILY SSF51735 48 289 1.77E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 Gene3D G3DSA:3.40.50.720 45 288 2.2E-82 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 288 3.4E-61 T 16-09-2016 Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 138 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 219 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 253 273 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 51 68 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 238 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 190 1.7E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 187 215 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PANTHER PTHR24322 200 232 2.0E-66 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PANTHER PTHR24322:SF566 200 232 2.0E-66 T 16-09-2016 Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PANTHER PTHR24322:SF566 54 184 2.0E-66 T 16-09-2016 Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 200 219 1.6E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 138 1.6E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 180 188 1.6E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00205 4877d30d8ec9e9a3b4d977ba9c75ee1d 292 PANTHER PTHR24322 54 184 2.0E-66 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15280 d3662969c34339ab548824e1d01cc40b 145 Pfam PF01475 Ferric uptake regulator family 13 122 7.4E-24 T 16-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spa2297_RS15280 d3662969c34339ab548824e1d01cc40b 145 PANTHER PTHR33202:SF7 5 139 1.2E-35 T 16-09-2016 Spa2297_RS15280 d3662969c34339ab548824e1d01cc40b 145 Gene3D G3DSA:1.10.10.10 5 82 4.3E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15280 d3662969c34339ab548824e1d01cc40b 145 SUPERFAMILY SSF46785 6 135 2.56E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15280 d3662969c34339ab548824e1d01cc40b 145 PANTHER PTHR33202 5 139 1.2E-35 T 16-09-2016 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 SUPERFAMILY SSF46689 276 326 4.56E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 PANTHER PTHR11019:SF58 4 330 1.1E-90 T 16-09-2016 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 Gene3D G3DSA:1.10.10.60 278 326 7.0E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 Gene3D G3DSA:1.10.10.60 231 277 4.8E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 Gene3D G3DSA:3.40.50.880 8 230 3.7E-54 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 SMART SM00342 239 322 1.8E-27 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 Pfam PF01965 DJ-1/PfpI family 8 184 2.3E-24 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 SUPERFAMILY SSF46689 223 272 2.96E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 318 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 Pfam PF12833 Helix-turn-helix domain 245 324 1.2E-23 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 PANTHER PTHR11019 4 330 1.1E-90 T 16-09-2016 Spa2297_RS09730 e800e18b117ecec717d51b1790e3eea3 330 SUPERFAMILY SSF52317 8 204 1.6E-48 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS09550 ce662c83849d953f1954c8f669301cf4 108 Gene3D G3DSA:3.10.450.50 12 104 4.4E-11 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS09550 ce662c83849d953f1954c8f669301cf4 108 SUPERFAMILY SSF54427 12 103 9.0E-12 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 PANTHER PTHR10000 88 268 1.5E-112 T 16-09-2016 Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 Pfam PF12710 haloacid dehalogenase-like hydrolase 40 226 1.4E-28 T 16-09-2016 Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 Gene3D G3DSA:3.40.50.1000 112 256 4.0E-48 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 39 229 3.7E-16 T 16-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 PANTHER PTHR10000:SF30 88 268 1.5E-112 T 16-09-2016 Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 SUPERFAMILY SSF56784 37 251 6.14E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18570 910e30f76ab5bf0964c4f6ed62dd63f9 290 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 39 241 6.1E-54 T 16-09-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 PANTHER PTHR21660:SF1 1 152 1.4E-112 T 16-09-2016 Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 SUPERFAMILY SSF54637 32 151 1.67E-27 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 Gene3D G3DSA:3.10.129.10 23 149 4.5E-46 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 Pfam PF03061 Thioesterase superfamily 62 139 2.0E-16 T 16-09-2016 IPR006683 Thioesterase domain Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 PANTHER PTHR21660 1 152 1.4E-112 T 16-09-2016 Spa2297_RS08145 43656c534a0101bc2cbf07cabac96939 159 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 146 1.2E-28 T 16-09-2016 IPR003736 Phenylacetic acid degradation-related domain Spa2297_RS29520 2a05c2657becf007ed18ac70dbde8198 211 Pfam PF13649 Methyltransferase domain 46 139 5.7E-14 T 16-09-2016 Spa2297_RS29520 2a05c2657becf007ed18ac70dbde8198 211 PANTHER PTHR10108:SF779 9 146 7.1E-19 T 16-09-2016 Spa2297_RS29520 2a05c2657becf007ed18ac70dbde8198 211 Gene3D G3DSA:3.40.50.150 25 209 3.3E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29520 2a05c2657becf007ed18ac70dbde8198 211 SUPERFAMILY SSF53335 11 190 5.93E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29520 2a05c2657becf007ed18ac70dbde8198 211 PANTHER PTHR10108 9 146 7.1E-19 T 16-09-2016 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 21.986 T 16-09-2016 IPR011605 NusB antitermination factor GO:0006353 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 Pfam PF01029 NusB family 6 133 4.7E-33 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 134 1.9E-38 T 16-09-2016 IPR011605 NusB antitermination factor GO:0006353 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 SUPERFAMILY SSF48013 4 132 6.8E-39 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 Gene3D G3DSA:1.10.940.10 2 132 2.2E-42 T 16-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spa2297_RS05620 54d0522412fd5385bbd4e4bcb3fdacd7 147 PANTHER PTHR11078 3 141 1.4E-46 T 16-09-2016 IPR011605 NusB antitermination factor GO:0006353 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SMART SM00958 226 350 4.8E-66 T 16-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SMART SM00957 4 404 2.7E-278 T 16-09-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SUPERFAMILY SSF52540 4 226 2.84E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SUPERFAMILY SSF52540 360 417 2.84E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SUPERFAMILY SSF81767 225 360 2.88E-41 T 16-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 837 0.0 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 851 19.697 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PANTHER PTHR30612 14 522 0.0 T 16-09-2016 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PANTHER PTHR30612 567 859 0.0 T 16-09-2016 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 ProSitePatterns PS01312 SecA family signature. 502 517 - T 16-09-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Gene3D G3DSA:1.10.3060.10 665 849 1.8E-59 T 16-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Gene3D G3DSA:3.90.1440.10 228 360 4.6E-45 T 16-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Pfam PF07516 SecA Wing and Scaffold domain 634 848 4.6E-67 T 16-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Pfam PF01043 SecA preprotein cross-linking domain 231 350 6.7E-35 T 16-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 168 188 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 368 385 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 115 125 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 331 353 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 99 113 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 61 85 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 PRINTS PR00906 SecA protein signature 415 428 7.9E-64 T 16-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SUPERFAMILY SSF52540 418 635 1.7E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Gene3D G3DSA:3.40.50.300 419 636 2.9E-93 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Pfam PF07517 SecA DEAD-like domain 5 403 4.0E-125 T 16-09-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Gene3D G3DSA:3.40.50.300 361 418 5.6E-121 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 Gene3D G3DSA:3.40.50.300 3 226 5.6E-121 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12975 60cc110a59c9640f3107553d647561cf 948 SUPERFAMILY SSF81886 637 861 1.96E-73 T 16-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 PANTHER PTHR13887 1 167 1.2E-91 T 16-09-2016 Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 Gene3D G3DSA:3.40.30.10 11 165 4.0E-32 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 SUPERFAMILY SSF52833 10 162 6.12E-28 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 Pfam PF01323 DSBA-like thioredoxin domain 14 58 7.0E-8 T 16-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 Pfam PF01323 DSBA-like thioredoxin domain 63 161 1.5E-17 T 16-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Spa2297_RS05875 d2fb8b53db829a573dd1f1b179f3f4e1 174 PANTHER PTHR13887:SF24 1 167 1.2E-91 T 16-09-2016 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 55 2.0E-17 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 PIRSF PIRSF006488 6 87 3.6E-26 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 Pfam PF02609 Exonuclease VII small subunit 17 66 7.5E-18 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 16 76 14.543 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 17 71 9.5E-20 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 PANTHER PTHR34137 4 87 1.2E-21 T 16-09-2016 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 Gene3D G3DSA:1.10.287.1040 13 80 1.8E-21 T 16-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21405 ee2bc70e5dfaaa91fc3314f29919ee60 88 SUPERFAMILY SSF116842 13 75 5.89E-16 T 16-09-2016 Spa2297_RS30715 fc388fd6c63a0a7240f7072fdcd14be0 212 Gene3D G3DSA:3.40.50.300 29 203 2.2E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30715 fc388fd6c63a0a7240f7072fdcd14be0 212 PANTHER PTHR11711 30 201 7.2E-60 T 16-09-2016 Spa2297_RS30715 fc388fd6c63a0a7240f7072fdcd14be0 212 PANTHER PTHR11711:SF117 30 201 7.2E-60 T 16-09-2016 Spa2297_RS30715 fc388fd6c63a0a7240f7072fdcd14be0 212 Pfam PF03029 Conserved hypothetical ATP binding protein 34 203 4.0E-25 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS30715 fc388fd6c63a0a7240f7072fdcd14be0 212 SUPERFAMILY SSF52540 30 203 2.95E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03510 b788303daceb1649b0e62b2787aaa008 231 Gene3D G3DSA:1.20.144.10 33 207 1.3E-35 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03510 b788303daceb1649b0e62b2787aaa008 231 Pfam PF01569 PAP2 superfamily 96 205 1.2E-18 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03510 b788303daceb1649b0e62b2787aaa008 231 SUPERFAMILY SSF48317 33 207 7.19E-35 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03510 b788303daceb1649b0e62b2787aaa008 231 SMART SM00014 91 203 3.0E-19 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS03510 b788303daceb1649b0e62b2787aaa008 231 PANTHER PTHR14969 55 203 3.1E-21 T 16-09-2016 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 PANTHER PTHR10066:SF44 308 877 1.3E-204 T 16-09-2016 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SUPERFAMILY SSF49899 894 1091 1.83E-38 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SMART SM00758 55 197 4.5E-25 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Gene3D G3DSA:2.60.40.320 487 590 1.1E-19 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SMART SM00560 952 1084 1.3E-21 T 16-09-2016 IPR006558 LamG-like jellyroll fold Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SUPERFAMILY SSF56988 56 203 1.44E-34 T 16-09-2016 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SUPERFAMILY SSF49785 321 495 6.24E-41 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Gene3D G3DSA:3.20.20.80 591 875 1.6E-45 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SUPERFAMILY SSF51445 589 872 8.56E-58 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Pfam PF00703 Glycosyl hydrolases family 2 499 592 3.8E-10 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 SUPERFAMILY SSF49303 500 593 1.44E-12 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Gene3D G3DSA:2.60.120.260 321 486 1.3E-51 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 368 491 4.9E-10 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Gene3D G3DSA:2.60.120.200 893 1091 6.1E-37 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 PANTHER PTHR10066 308 877 1.3E-204 T 16-09-2016 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Gene3D G3DSA:3.90.182.10 51 214 4.1E-41 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 935 1087 1.2E-29 T 16-09-2016 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 634 747 1.3E-6 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS00255 1b0dea98c04320b45229fcf52c598816 1095 Pfam PF07691 PA14 domain 57 193 1.2E-20 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS03425 c58335779a04df6de90ad6ff272a458c 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 20 154 1.3E-18 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS03425 c58335779a04df6de90ad6ff272a458c 157 Gene3D G3DSA:3.30.530.20 18 156 9.1E-15 T 16-09-2016 IPR023393 START-like domain Spa2297_RS03425 c58335779a04df6de90ad6ff272a458c 157 SUPERFAMILY SSF55961 19 156 3.67E-19 T 16-09-2016 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 181 1.3E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 SMART SM00387 26 183 2.8E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PANTHER PTHR11528:SF44 2 633 0.0 T 16-09-2016 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 SUPERFAMILY SSF54211 234 487 9.86E-92 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 Pfam PF00183 Hsp90 protein 227 630 9.9E-126 T 16-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PIRSF PIRSF002583 1 632 3.6E-210 T 16-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 630 29.983 T 16-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 SUPERFAMILY SSF55874 3 219 4.9E-61 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PANTHER PTHR11528 2 633 0.0 T 16-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 SUPERFAMILY SSF110942 514 629 4.45E-30 T 16-09-2016 Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 121 143 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 25 47 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 171 188 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 92 109 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 194 212 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 4 24 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 PRINTS PR00775 90kDa heat shock protein signature 74 91 1.5E-56 T 16-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 Gene3D G3DSA:3.30.565.10 4 241 2.7E-76 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01175 efaa75943a2833cb7466535e7365afc8 633 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 24 33 - T 16-09-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 Pfam PF00318 Ribosomal protein S2 9 225 3.4E-95 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 Gene3D G3DSA:3.40.50.10490 23 99 4.2E-67 T 16-09-2016 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 Gene3D G3DSA:3.40.50.10490 159 233 4.2E-67 T 16-09-2016 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 SUPERFAMILY SSF52313 6 226 3.66E-90 T 16-09-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 1.9E-106 T 16-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 Gene3D G3DSA:1.10.287.610 100 153 3.9E-21 T 16-09-2016 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 16-09-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PANTHER PTHR12534 1 272 1.6E-113 T 16-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 159 176 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 176 187 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 87 104 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 6 24 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 197 211 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 PRINTS PR00395 Ribosomal protein S2 signature 37 46 8.2E-39 T 16-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23820 5c17e2a11f8f4069678445dce51d2fdb 307 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.079 T 16-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 Pfam PF02195 ParB-like nuclease domain 88 176 7.8E-26 T 16-09-2016 IPR003115 ParB/Sulfiredoxin Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 SUPERFAMILY SSF110849 88 179 2.96E-28 T 16-09-2016 IPR003115 ParB/Sulfiredoxin Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 85 262 1.6E-59 T 16-09-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 PANTHER PTHR33375 47 366 1.8E-104 T 16-09-2016 Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 SMART SM00470 87 177 1.0E-34 T 16-09-2016 IPR003115 ParB/Sulfiredoxin Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 SUPERFAMILY SSF109709 169 278 1.31E-33 T 16-09-2016 Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 PANTHER PTHR33375:SF1 47 366 1.8E-104 T 16-09-2016 Spa2297_RS16540 21d2a41bafc1d4e5f2eee54e942b0ce3 367 Gene3D G3DSA:3.90.1530.10 84 183 9.4E-38 T 16-09-2016 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 SUPERFAMILY SSF51556 4 250 2.95E-105 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 SUPERFAMILY SSF51556 290 377 2.95E-105 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 PANTHER PTHR10443:SF26 290 380 5.4E-229 T 16-09-2016 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 PANTHER PTHR10443 4 250 5.4E-229 T 16-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 PANTHER PTHR10443 290 380 5.4E-229 T 16-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 PANTHER PTHR10443:SF26 4 250 5.4E-229 T 16-09-2016 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 10 367 9.6E-119 T 16-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 Spa2297_RS13250 efdab65f6ca1d650bd45e13ea7eb827a 392 Gene3D G3DSA:3.20.20.140 4 385 2.1E-148 T 16-09-2016 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 Pfam PF12697 Alpha/beta hydrolase family 38 277 3.6E-23 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PANTHER PTHR10992 1 285 1.0E-104 T 16-09-2016 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 SUPERFAMILY SSF53474 11 284 9.37E-56 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 Gene3D G3DSA:3.40.50.1820 6 284 1.6E-65 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PANTHER PTHR10992:SF877 1 285 1.0E-104 T 16-09-2016 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.1E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.1E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 1.1E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS14450 3bb113b08559b76703ce1bb9f95f997e 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.1E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 162 175 140.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 177 219 5.9 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 381 411 0.0044 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 320 347 3.2 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 536 552 1.2 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 503 520 0.022 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 254 283 13.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 363 379 12.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 444 488 4.9E-8 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Pfam PF08238 Sel1 repeat 113 143 0.11 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SUPERFAMILY SSF81901 471 586 2.22E-21 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 PANTHER PTHR11102 467 562 2.6E-60 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 PANTHER PTHR11102 230 426 2.6E-60 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 PANTHER PTHR11102:SF11 467 562 2.6E-60 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 PANTHER PTHR11102:SF11 230 426 2.6E-60 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Gene3D G3DSA:1.25.40.10 380 599 5.5E-43 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Gene3D G3DSA:1.25.40.10 205 379 2.6E-38 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 Gene3D G3DSA:1.25.40.10 18 199 7.0E-26 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SUPERFAMILY SSF81901 224 441 3.09E-28 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SUPERFAMILY SSF81901 39 143 4.84E-14 T 16-09-2016 Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 284 315 16.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 380 411 0.2 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 220 251 150.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 144 175 2.6 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 553 584 160.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 521 552 1.8 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 48 79 150.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 489 520 5.1 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 112 143 0.09 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 348 379 3.4 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 80 111 180.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 444 488 12.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 316 347 80.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 252 283 7.8 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS21995 08e4d620d41b7ccd1995cd3e479bcf5e 604 SMART SM00671 176 219 51.0 T 16-09-2016 IPR006597 Sel1-like repeat Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 289 7.1E-40 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 Gene3D G3DSA:3.40.50.720 130 297 3.9E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PANTHER PTHR10836:SF35 117 476 2.3E-234 T 16-09-2016 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 131 463 8.1E-113 T 16-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 247 260 2.3E-18 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 366 383 2.3E-18 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 283 301 2.3E-18 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 310 326 2.3E-18 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 SMART SM00846 129 289 2.4E-54 T 16-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 SUPERFAMILY SSF55347 289 452 2.65E-48 T 16-09-2016 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 287 294 - T 16-09-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 Gene3D G3DSA:3.30.360.10 298 453 4.3E-50 T 16-09-2016 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 PANTHER PTHR10836 117 476 2.3E-234 T 16-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 SUPERFAMILY SSF51735 129 309 4.09E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03165 dc08e6febeb4207299b0e832b362e010 481 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 294 451 3.3E-43 T 16-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 Spa2297_RS04755 e72bf5b2728acc7cf8ba4c1262312545 162 SUPERFAMILY SSF52821 35 145 1.18E-24 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS04755 e72bf5b2728acc7cf8ba4c1262312545 162 Gene3D G3DSA:3.40.250.10 37 145 2.5E-21 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS04755 e72bf5b2728acc7cf8ba4c1262312545 162 Pfam PF00581 Rhodanese-like domain 41 132 1.1E-14 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS04755 e72bf5b2728acc7cf8ba4c1262312545 162 SMART SM00450 39 136 6.6E-19 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 PANTHER PTHR24421 90 412 3.2E-75 T 16-09-2016 Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 SUPERFAMILY SSF103473 24 193 5.36E-5 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 PANTHER PTHR24421:SF22 90 412 3.2E-75 T 16-09-2016 Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 Pfam PF13581 Histidine kinase-like ATPase domain 293 366 1.9E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 Pfam PF07730 Histidine kinase 213 280 2.9E-12 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS15830 17fcad360a74b5b354fd2485eb646631 412 SUPERFAMILY SSF55874 307 400 1.52E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 PRINTS PR00352 3Fe-4S ferredoxin signature 18 29 3.1E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 PRINTS PR00352 3Fe-4S ferredoxin signature 72 84 3.1E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 PRINTS PR00352 3Fe-4S ferredoxin signature 29 39 3.1E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 PANTHER PTHR39163:SF1 12 99 3.4E-28 T 16-09-2016 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 SUPERFAMILY SSF54862 15 86 3.28E-9 T 16-09-2016 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 PANTHER PTHR39163 12 99 3.4E-28 T 16-09-2016 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 Pfam PF13459 4Fe-4S single cluster domain 16 86 2.3E-18 T 16-09-2016 Spa2297_RS06395 f0571ea57bd04ba7b56aa94ec89776b5 101 Gene3D G3DSA:3.30.70.20 14 98 1.1E-26 T 16-09-2016 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 Gene3D G3DSA:3.40.50.720 3 187 4.9E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 16-09-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 SUPERFAMILY SSF51735 3 182 5.14E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 5.5E-69 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 PANTHER PTHR23309 3 281 2.0E-136 T 16-09-2016 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 SUPERFAMILY SSF48179 186 281 8.42E-27 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 Gene3D G3DSA:1.10.1040.10 188 281 4.0E-29 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 1.4E-29 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS22755 54025e0897df70120eef7b19865b924f 282 PIRSF PIRSF000105 1 282 9.8E-92 T 16-09-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 ProSitePatterns PS00510 Malate synthase signature. 269 284 - T 16-09-2016 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 Gene3D G3DSA:3.20.20.360 72 415 7.3E-119 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 Gene3D G3DSA:1.20.1220.12 419 532 2.1E-26 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 PANTHER PTHR21631 159 538 4.9E-261 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 Pfam PF01274 Malate synthase 18 538 2.0E-203 T 16-09-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 PIRSF PIRSF001363 3 540 4.5E-243 T 16-09-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 PANTHER PTHR21631:SF1 12 143 4.9E-261 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 538 2.8E-255 T 16-09-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 PANTHER PTHR21631:SF1 159 538 4.9E-261 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 PANTHER PTHR21631 12 143 4.9E-261 T 16-09-2016 Spa2297_RS26415 23572904aaf394cb0f4e15b78a4161c3 540 SUPERFAMILY SSF51645 18 539 3.92E-182 T 16-09-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 PANTHER PTHR11645:SF0 1 270 8.1E-122 T 16-09-2016 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 5.4E-39 T 16-09-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 PIRSF PIRSF000193 2 267 3.7E-76 T 16-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 Gene3D G3DSA:1.10.3730.10 159 264 2.6E-42 T 16-09-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 5.9E-81 T 16-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 PANTHER PTHR11645 1 270 8.1E-122 T 16-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 26.45 T 16-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 16-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 2.2E-21 T 16-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 SUPERFAMILY SSF51735 4 158 3.19E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 Gene3D G3DSA:3.40.50.720 2 157 1.3E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18490 bdec12b44a751e5064b24bf4d167c7c9 270 SUPERFAMILY SSF48179 159 265 2.21E-36 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 SUPERFAMILY SSF54826 16 150 4.77E-51 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PANTHER PTHR11902 13 432 1.9E-239 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 Hamap MF_00318 Enolase [eno]. 15 424 43.107 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 SMART SM01192 152 438 1.1E-202 T 16-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 Pfam PF03952 Enolase, N-terminal domain 17 147 1.1E-54 T 16-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 Gene3D G3DSA:3.30.390.10 17 138 4.9E-50 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 Gene3D G3DSA:3.20.20.120 141 436 9.0E-126 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 347 361 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 376 393 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 120 136 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 50 64 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 174 187 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PRINTS PR00148 Enolase signature 324 335 2.8E-44 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 SUPERFAMILY SSF51604 152 434 3.81E-119 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 Pfam PF00113 Enolase, C-terminal TIM barrel domain 153 436 5.9E-118 T 16-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 PIRSF PIRSF001400 13 437 2.1E-176 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 SMART SM01193 17 147 1.0E-83 T 16-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 ProSitePatterns PS00164 Enolase signature. 347 360 - T 16-09-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS31825 cdb97aaf029afbf0c16094fec35916d6 439 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 17 435 1.5E-190 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04635 e80ec148ab63fd2c157a38766590d9dc 163 SUPERFAMILY SSF55961 38 137 5.15E-9 T 16-09-2016 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 Pfam PF00892 EamA-like transporter family 160 304 1.2E-13 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 Pfam PF00892 EamA-like transporter family 21 147 3.6E-14 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 PANTHER PTHR12715 12 330 3.5E-95 T 16-09-2016 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 PANTHER PTHR12715:SF4 12 330 3.5E-95 T 16-09-2016 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 SUPERFAMILY SSF103481 230 307 3.14E-11 T 16-09-2016 Spa2297_RS04995 8422ae6d4e4151857a92ac4c506f679e 334 SUPERFAMILY SSF103481 52 148 3.27E-11 T 16-09-2016 Spa2297_RS28470 0b01845cc91848248a2e51ce5a6decc4 295 Gene3D G3DSA:3.20.20.70 26 283 6.9E-38 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS28470 0b01845cc91848248a2e51ce5a6decc4 295 SUPERFAMILY SSF51569 26 281 4.03E-36 T 16-09-2016 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 Pfam PF01895 PhoU domain 16 103 1.2E-18 T 16-09-2016 IPR026022 PhoU domain Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 Pfam PF01895 PhoU domain 121 204 9.2E-12 T 16-09-2016 IPR026022 PhoU domain Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 Gene3D G3DSA:1.20.58.220 116 218 4.9E-21 T 16-09-2016 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 PANTHER PTHR10010:SF14 1 219 4.2E-58 T 16-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 SUPERFAMILY SSF109755 2 216 5.76E-58 T 16-09-2016 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 PIRSF PIRSF003107 1 216 8.1E-55 T 16-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 Gene3D G3DSA:1.20.58.220 1 105 7.5E-29 T 16-09-2016 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.1E-56 T 16-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Spa2297_RS15110 028d7e0989f1b77e47da2eeee902decd 230 PANTHER PTHR10010 1 219 4.2E-58 T 16-09-2016 Spa2297_RS20095 c28a4ee8ea156b7cc082ac51181ffa6c 228 SUPERFAMILY SSF50800 5 224 6.28E-55 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS20095 c28a4ee8ea156b7cc082ac51181ffa6c 228 PANTHER PTHR30212 4 225 3.6E-50 T 16-09-2016 Spa2297_RS20095 c28a4ee8ea156b7cc082ac51181ffa6c 228 Pfam PF03473 MOSC domain 63 176 9.3E-24 T 16-09-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Spa2297_RS20095 c28a4ee8ea156b7cc082ac51181ffa6c 228 Gene3D G3DSA:2.40.33.20 5 225 1.4E-72 T 16-09-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like Spa2297_RS20095 c28a4ee8ea156b7cc082ac51181ffa6c 228 PANTHER PTHR30212:SF2 4 225 3.6E-50 T 16-09-2016 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 Pfam PF13646 HEAT repeats 177 257 2.5E-8 T 16-09-2016 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SMART SM00567 E-Z type HEAT repeats 220 249 200.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SMART SM00567 E-Z type HEAT repeats 189 218 0.26 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SMART SM00567 E-Z type HEAT repeats 287 316 85.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 Pfam PF13411 MerR HTH family regulatory protein 3 68 3.3E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 Gene3D G3DSA:1.10.1660.10 3 101 8.6E-26 T 16-09-2016 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 Gene3D G3DSA:1.25.10.10 118 328 2.3E-14 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 PANTHER PTHR30204 3 102 4.9E-21 T 16-09-2016 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SUPERFAMILY SSF46955 3 102 1.54E-23 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SUPERFAMILY SSF48371 118 328 4.87E-17 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.6E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00405 87f39da580e2e1ecb0e6fa854232fa36 332 SMART SM00422 1 70 2.5E-21 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 PANTHER PTHR22924:SF2 5 382 2.2E-121 T 16-09-2016 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 SUPERFAMILY SSF52343 243 371 1.7E-24 T 16-09-2016 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 171 183 6.6E-11 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 249 268 6.6E-11 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 339 347 6.6E-11 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Pfam PF00970 Oxidoreductase FAD-binding domain 168 238 4.3E-11 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 SUPERFAMILY SSF63380 144 239 6.63E-20 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 SUPERFAMILY SSF46458 1 130 2.16E-31 T 16-09-2016 IPR009050 Globin-like Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Gene3D G3DSA:1.10.490.10 4 136 1.9E-35 T 16-09-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Pfam PF00042 Globin 5 99 5.1E-8 T 16-09-2016 IPR000971 Globin GO:0019825|GO:0020037 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 PANTHER PTHR22924 5 382 2.2E-121 T 16-09-2016 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Gene3D G3DSA:2.40.30.10 144 239 1.7E-20 T 16-09-2016 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Pfam PF00175 Oxidoreductase NAD-binding domain 252 353 1.5E-11 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS29400 2d28c231f67f36c545f7b7bfcea4d429 393 Gene3D G3DSA:3.40.50.80 244 370 4.1E-27 T 16-09-2016 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 PANTHER PTHR26402:SF151 1 212 2.0E-63 T 16-09-2016 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 Gene3D G3DSA:3.40.50.2300 1 114 1.5E-30 T 16-09-2016 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 SUPERFAMILY SSF46894 145 212 1.67E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 PANTHER PTHR26402 1 212 2.0E-63 T 16-09-2016 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 Gene3D G3DSA:1.10.10.10 115 212 2.3E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 SMART SM00448 1 110 2.2E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.9E-20 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 SMART SM00421 150 207 1.0E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.0E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.0E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.0E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 SUPERFAMILY SSF52172 1 116 4.13E-30 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 Pfam PF00072 Response regulator receiver domain 1 110 4.5E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08710 ab77be41f3b907cabafc5d31f2135cf1 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 SMART SM00363 135 195 1.8E-10 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 PANTHER PTHR21600:SF2 131 371 3.3E-80 T 16-09-2016 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 Pfam PF00849 RNA pseudouridylate synthase 197 327 1.5E-23 T 16-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 SUPERFAMILY SSF55120 180 367 4.93E-43 T 16-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 PANTHER PTHR21600 131 371 3.3E-80 T 16-09-2016 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 Gene3D G3DSA:3.10.290.10 133 194 2.0E-21 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 SUPERFAMILY SSF55174 127 200 3.73E-12 T 16-09-2016 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 Pfam PF01479 S4 domain 135 180 2.6E-12 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 233 247 - T 16-09-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spa2297_RS06965 bc64b46a7ad8f2cf6a562ed162419f84 371 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 200 358 4.1E-43 T 16-09-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spa2297_RS27190 5a2822c2b96f07c6d1ef8097c94ad90c 257 Gene3D G3DSA:3.60.15.10 3 254 2.9E-51 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27190 5a2822c2b96f07c6d1ef8097c94ad90c 257 Pfam PF12706 Beta-lactamase superfamily domain 21 206 2.9E-30 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27190 5a2822c2b96f07c6d1ef8097c94ad90c 257 PANTHER PTHR15032 3 253 3.1E-53 T 16-09-2016 Spa2297_RS27190 5a2822c2b96f07c6d1ef8097c94ad90c 257 SUPERFAMILY SSF56281 4 74 2.66E-28 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27190 5a2822c2b96f07c6d1ef8097c94ad90c 257 SUPERFAMILY SSF56281 101 211 2.66E-28 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS26040 f1d8fcdb50d891a8da7584f05f2d48f6 362 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 163 349 6.8E-43 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26040 f1d8fcdb50d891a8da7584f05f2d48f6 362 PANTHER PTHR21021:SF19 105 358 3.3E-45 T 16-09-2016 Spa2297_RS26040 f1d8fcdb50d891a8da7584f05f2d48f6 362 PANTHER PTHR21021 105 358 3.3E-45 T 16-09-2016 Spa2297_RS26040 f1d8fcdb50d891a8da7584f05f2d48f6 362 SUPERFAMILY SSF81606 144 349 1.65E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26040 f1d8fcdb50d891a8da7584f05f2d48f6 362 SMART SM00331 135 349 2.5E-30 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS23260 d30cb924e1a48c11f819f9567727e99b 98 PANTHER PTHR15004 1 98 5.9E-31 T 16-09-2016 Spa2297_RS23260 d30cb924e1a48c11f819f9567727e99b 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.631 T 16-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Spa2297_RS23260 d30cb924e1a48c11f819f9567727e99b 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.9E-24 T 16-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Spa2297_RS23260 d30cb924e1a48c11f819f9567727e99b 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.4E-17 T 16-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Spa2297_RS23260 d30cb924e1a48c11f819f9567727e99b 98 SUPERFAMILY SSF141000 4 94 6.93E-28 T 16-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 Gene3D G3DSA:3.40.50.200 140 504 1.2E-80 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 426 436 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795:SF419 141 326 2.0E-68 T 16-09-2016 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795:SF419 6 106 2.0E-68 T 16-09-2016 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 229 1.7E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 168 187 1.7E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PRINTS PR00723 Subtilisin serine protease family (S8) signature 425 441 1.7E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 173 184 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 SUPERFAMILY SSF52743 354 504 8.38E-76 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 SUPERFAMILY SSF52743 149 327 8.38E-76 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795 141 326 2.0E-68 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795 6 106 2.0E-68 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795:SF419 350 503 2.0E-68 T 16-09-2016 Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 220 230 - T 16-09-2016 IPR022398 Peptidase S8, subtilisin, His-active site Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 PANTHER PTHR10795 350 503 2.0E-68 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS07275 a1b237ca75d6da2651852f7fb4c53005 505 Pfam PF00082 Subtilase family 169 495 6.7E-46 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 Gene3D G3DSA:3.60.20.10 411 488 7.5E-60 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 Gene3D G3DSA:3.60.20.10 575 815 7.5E-60 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 Pfam PF01804 Penicillin amidase 146 922 3.1E-117 T 16-09-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 SUPERFAMILY SSF56235 403 807 3.34E-106 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 SUPERFAMILY SSF56235 145 350 3.34E-106 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 Gene3D G3DSA:1.10.439.10 143 305 1.3E-36 T 16-09-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 Gene3D G3DSA:2.30.120.10 489 543 3.7E-4 T 16-09-2016 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 PANTHER PTHR34218:SF2 407 935 1.9E-183 T 16-09-2016 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 PANTHER PTHR34218:SF2 88 385 1.9E-183 T 16-09-2016 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 PANTHER PTHR34218 88 385 1.9E-183 T 16-09-2016 Spa2297_RS06630 e84ac75997f614190b1152edcb7e45b4 935 PANTHER PTHR34218 407 935 1.9E-183 T 16-09-2016 Spa2297_RS25715 9811932481193910ac286512022d9548 435 Pfam PF01547 Bacterial extracellular solute-binding protein 57 342 1.9E-39 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS25715 9811932481193910ac286512022d9548 435 PANTHER PTHR30061 4 435 6.8E-109 T 16-09-2016 Spa2297_RS25715 9811932481193910ac286512022d9548 435 SUPERFAMILY SSF53850 37 424 2.59E-62 T 16-09-2016 Spa2297_RS25715 9811932481193910ac286512022d9548 435 PANTHER PTHR30061:SF24 4 435 6.8E-109 T 16-09-2016 Spa2297_RS25715 9811932481193910ac286512022d9548 435 Gene3D G3DSA:3.40.190.10 47 168 7.0E-15 T 16-09-2016 Spa2297_RS25715 9811932481193910ac286512022d9548 435 Gene3D G3DSA:3.40.190.10 169 363 1.8E-28 T 16-09-2016 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 Gene3D G3DSA:1.10.10.10 19 118 4.1E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 Pfam PF01022 Bacterial regulatory protein, arsR family 44 91 3.4E-16 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 SUPERFAMILY SSF46785 21 117 2.3E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PANTHER PTHR33154 15 124 6.4E-41 T 16-09-2016 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 SMART SM00418 37 117 5.5E-29 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PANTHER PTHR33154:SF4 15 124 6.4E-41 T 16-09-2016 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 63 81 - T 16-09-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 72 6.6E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 6.6E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 6.6E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14090 c60db45c45e7bc4f3e6e76e62f606768 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 6.6E-23 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS31040 6ba4c28fb7cb58b3d05f62a03183b11f 144 Pfam PF09656 Putative transmembrane protein (PGPGW) 10 51 8.5E-11 T 16-09-2016 IPR019099 Uncharacterised protein family PGPGW, transmembrane Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 PANTHER PTHR30055 17 208 6.7E-88 T 16-09-2016 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 PANTHER PTHR30055:SF14 17 208 6.7E-88 T 16-09-2016 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 SUPERFAMILY SSF46689 22 94 1.4E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 3.9E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 Gene3D G3DSA:1.10.357.10 21 201 1.2E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.0E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09700 6d217a54a41354904750e7954ba69766 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.0E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS04490 c59e6d8556d2b631f91f06bfc009b1c8 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 53 3.0E-17 T 16-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spa2297_RS04490 c59e6d8556d2b631f91f06bfc009b1c8 93 SUPERFAMILY SSF143120 5 51 1.83E-11 T 16-09-2016 Spa2297_RS04490 c59e6d8556d2b631f91f06bfc009b1c8 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 52 7.5E-14 T 16-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spa2297_RS04490 c59e6d8556d2b631f91f06bfc009b1c8 93 Gene3D G3DSA:3.40.1620.10 3 51 1.0E-14 T 16-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spa2297_RS32090 efc647cbb11b30c6a25883fa2c2bb469 280 PANTHER PTHR32243 1 280 2.6E-150 T 16-09-2016 Spa2297_RS32090 efc647cbb11b30c6a25883fa2c2bb469 280 SUPERFAMILY SSF161098 11 280 2.75E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32090 efc647cbb11b30c6a25883fa2c2bb469 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 268 7.8E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32090 efc647cbb11b30c6a25883fa2c2bb469 280 Gene3D G3DSA:1.10.3720.10 9 267 1.5E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32090 efc647cbb11b30c6a25883fa2c2bb469 280 PANTHER PTHR32243:SF24 1 280 2.6E-150 T 16-09-2016 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Pfam PF12836 Helix-hairpin-helix motif 499 563 4.1E-28 T 16-09-2016 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 PANTHER PTHR10724 14 764 0.0 T 16-09-2016 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:1.10.150.310 507 638 3.0E-45 T 16-09-2016 IPR023097 Tex RuvX-like domain Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SUPERFAMILY SSF50249 646 733 3.51E-23 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:1.10.3500.10 120 329 1.3E-98 T 16-09-2016 IPR023323 Tex-like domain Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:1.10.3500.10 459 506 1.3E-98 T 16-09-2016 IPR023323 Tex-like domain Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SMART SM00316 657 728 2.5E-23 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:2.40.50.140 642 728 6.0E-26 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 PANTHER PTHR10724:SF1 14 764 0.0 T 16-09-2016 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SMART SM00732 333 432 1.8E-37 T 16-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Pfam PF16921 Tex protein YqgF-like domain 334 459 5.6E-51 T 16-09-2016 IPR032639 Tex protein, YqgF-like domain Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:1.10.10.650 14 119 9.2E-44 T 16-09-2016 IPR023319 Tex-like protein, HTH domain Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Gene3D G3DSA:3.30.420.140 333 458 2.3E-50 T 16-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Pfam PF00575 S1 RNA binding domain 658 728 4.2E-18 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SUPERFAMILY SSF47781 478 566 2.67E-27 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SUPERFAMILY SSF158832 14 328 5.75E-112 T 16-09-2016 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SUPERFAMILY SSF47781 569 639 3.11E-19 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 SUPERFAMILY SSF53098 329 477 1.29E-49 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS28080 ff5144cea48691ff578fcc518f548354 786 Pfam PF09371 Tex-like protein N-terminal domain 19 202 9.2E-66 T 16-09-2016 IPR018974 Tex-like protein, N-terminal Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 Pfam PF02566 OsmC-like protein 44 136 4.4E-19 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 PANTHER PTHR33797:SF1 1 140 3.1E-54 T 16-09-2016 Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 PANTHER PTHR33797 1 140 3.1E-54 T 16-09-2016 Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 SUPERFAMILY SSF82784 3 132 4.97E-33 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 Gene3D G3DSA:3.30.300.20 4 140 3.1E-44 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS27210 7869af883f70ce44adba37c0a0180f00 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 3.4E-52 T 16-09-2016 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 SUPERFAMILY SSF53738 24 235 8.48E-47 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 9.1E-11 T 16-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 3 543 6.5E-278 T 16-09-2016 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 39 180 6.6E-35 T 16-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 SUPERFAMILY SSF55957 434 545 8.63E-18 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Gene3D G3DSA:3.40.120.10 311 444 8.2E-34 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Gene3D G3DSA:3.40.120.10 226 310 2.6E-44 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 16-09-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 SUPERFAMILY SSF53738 209 317 1.41E-5 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 SUPERFAMILY SSF53738 306 448 2.59E-33 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 439 3.1E-28 T 16-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Gene3D G3DSA:3.40.120.10 28 225 1.6E-56 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Gene3D G3DSA:3.30.310.50 467 541 3.6E-26 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 PANTHER PTHR22573 17 546 1.3E-278 T 16-09-2016 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 PANTHER PTHR22573:SF52 17 546 1.3E-278 T 16-09-2016 Spa2297_RS01540 7ef9d75e93cb7a12e28d1642da6563ff 546 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 481 537 6.4E-8 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 PANTHER PTHR12029:SF58 67 313 4.1E-69 T 16-09-2016 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 Gene3D G3DSA:3.30.1330.30 67 145 3.6E-19 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 72 149 1.1E-19 T 16-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 Pfam PF00588 SpoU rRNA Methylase family 166 307 7.2E-33 T 16-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 SUPERFAMILY SSF55315 67 146 3.88E-15 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 SUPERFAMILY SSF75217 137 313 3.47E-42 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 70 313 1.6E-60 T 16-09-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 PANTHER PTHR12029 67 313 4.1E-69 T 16-09-2016 Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 Gene3D G3DSA:3.40.1280.10 161 313 2.0E-47 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS15070 5ac712a79f34d205cb19754353b8d8ad 314 SMART SM00967 72 149 3.8E-20 T 16-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PANTHER PTHR11938 335 468 1.7E-143 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PANTHER PTHR11938 12 318 1.7E-143 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 SUPERFAMILY SSF51971 144 401 8.24E-67 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Gene3D G3DSA:3.50.50.60 388 472 2.3E-14 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 457 2.4E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 SUPERFAMILY SSF46548 10 155 5.23E-35 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.0E-24 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.0E-24 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.0E-24 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.0E-24 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Gene3D G3DSA:3.40.50.720 148 239 2.0E-30 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PANTHER PTHR11938:SF75 335 468 1.7E-143 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 PANTHER PTHR11938:SF75 12 318 1.7E-143 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 475 6.8E-206 T 16-09-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Gene3D G3DSA:3.50.50.60 240 387 3.7E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Gene3D G3DSA:1.10.1060.10 2 147 1.5E-35 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 SUPERFAMILY SSF51971 361 468 4.47E-10 T 16-09-2016 Spa2297_RS08240 46dc3aa63be5fbba137ce669708b13c1 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 40 131 1.2E-20 T 16-09-2016 IPR028261 Dihydroprymidine dehydrogenase domain II Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 Gene3D G3DSA:3.30.530.20 99 263 1.7E-26 T 16-09-2016 IPR023393 START-like domain Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 Pfam PF12840 Helix-turn-helix domain 2 62 1.1E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 SUPERFAMILY SSF46785 1 116 6.27E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 256 5.1E-21 T 16-09-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 SMART SM00418 3 78 5.3E-16 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 PANTHER PTHR38600 1 123 1.8E-19 T 16-09-2016 Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 Gene3D G3DSA:1.10.10.10 1 98 2.1E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 SUPERFAMILY SSF55961 102 262 2.2E-27 T 16-09-2016 Spa2297_RS11580 f89ad689cc01d9d540a69330aeadf4cd 265 PANTHER PTHR38600:SF1 1 123 1.8E-19 T 16-09-2016 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 PANTHER PTHR11374 9 389 1.3E-149 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 Gene3D G3DSA:3.40.50.720 10 227 2.5E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 413 6.9E-11 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 297 4.2E-25 T 16-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 Gene3D G3DSA:3.40.50.720 243 414 4.0E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 SMART SM00984 324 417 2.1E-10 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 PIRSF PIRSF500136 1 425 9.1E-136 T 16-09-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 PIRSF PIRSF000124 9 414 1.2E-56 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 10 414 1.4E-117 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 PANTHER PTHR11374:SF4 9 389 1.3E-149 T 16-09-2016 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 SUPERFAMILY SSF48179 206 297 4.93E-27 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 SUPERFAMILY SSF51735 10 194 4.03E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 SUPERFAMILY SSF52413 310 414 1.44E-18 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS21385 73cf73b509d463bc7f625f3b2f1afd58 430 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 189 2.9E-35 T 16-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Pfam PF07687 Peptidase dimerisation domain 200 332 8.9E-15 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Pfam PF01546 Peptidase family M20/M25/M40 83 440 8.4E-38 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 PANTHER PTHR11014 13 441 3.6E-111 T 16-09-2016 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Gene3D G3DSA:3.30.70.360 292 331 7.2E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Gene3D G3DSA:3.30.70.360 213 252 7.2E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 PANTHER PTHR11014:SF106 13 441 3.6E-111 T 16-09-2016 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 82 91 - T 16-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Gene3D G3DSA:3.40.630.10 14 212 9.0E-62 T 16-09-2016 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 Gene3D G3DSA:3.40.630.10 377 441 9.0E-62 T 16-09-2016 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 SUPERFAMILY SSF55031 203 242 3.14E-10 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 SUPERFAMILY SSF55031 291 332 3.14E-10 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 SUPERFAMILY SSF53187 13 203 9.29E-58 T 16-09-2016 Spa2297_RS30750 66c9d1124da051232244021c4331c6eb 442 SUPERFAMILY SSF53187 352 441 9.29E-58 T 16-09-2016 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 Gene3D G3DSA:1.10.10.60 263 309 1.5E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 PANTHER PTHR11019 4 310 2.4E-102 T 16-09-2016 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 Pfam PF01965 DJ-1/PfpI family 4 168 1.0E-14 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 Pfam PF12833 Helix-turn-helix domain 231 309 3.7E-23 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 SUPERFAMILY SSF46689 262 309 9.86E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 PANTHER PTHR11019:SF68 4 310 2.4E-102 T 16-09-2016 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 SUPERFAMILY SSF52317 1 188 3.23E-43 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 SMART SM00342 225 308 7.8E-32 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 SUPERFAMILY SSF46689 211 259 6.49E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 Gene3D G3DSA:1.10.10.60 216 262 8.3E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30625 df77a8d8147e8ff398eb0e31a77582df 310 Gene3D G3DSA:3.40.50.880 3 215 9.9E-47 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 186 2.6E-22 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 30 189 3.9E-57 T 16-09-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 Gene3D G3DSA:1.10.1740.10 33 103 7.2E-15 T 16-09-2016 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 Gene3D G3DSA:1.10.10.10 126 188 1.2E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 SUPERFAMILY SSF88659 114 188 8.22E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 SUPERFAMILY SSF88946 33 104 1.29E-14 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 PANTHER PTHR30173 39 191 2.8E-27 T 16-09-2016 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 Pfam PF04542 Sigma-70 region 2 39 103 2.4E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17755 8700395939a149d175b9060d8abc3224 191 Pfam PF08281 Sigma-70, region 4 131 183 4.7E-12 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 SUPERFAMILY SSF49879 54 172 2.1E-31 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 Pfam PF00498 FHA domain 102 165 1.1E-19 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 SMART SM00240 100 151 8.4E-13 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 Gene3D G3DSA:2.60.200.20 79 173 8.6E-30 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 Pfam PF13240 zinc-ribbon domain 5 27 2.7E-8 T 16-09-2016 IPR026870 Zinc-ribbon domain Spa2297_RS05075 416f444b2c854bd9632d61747ffe8e4a 178 PANTHER PTHR15715 54 165 5.5E-32 T 16-09-2016 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 SUPERFAMILY SSF90123 47 365 4.84E-62 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 ProSitePatterns PS00211 ABC transporters family signature. 520 534 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 SMART SM00382 408 594 4.1E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 Gene3D G3DSA:3.40.50.300 383 608 2.8E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 SUPERFAMILY SSF52540 379 617 1.31E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 Pfam PF00005 ABC transporter 402 548 2.2E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 Pfam PF00664 ABC transporter transmembrane region 61 326 1.2E-26 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 PANTHER PTHR24221 49 617 1.0E-172 T 16-09-2016 Spa2297_RS23050 d007c2ed89dff8072a9c2cf1381919d1 623 Gene3D G3DSA:1.20.1560.10 47 363 3.7E-73 T 16-09-2016 Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.0E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 Gene3D G3DSA:3.40.50.720 6 248 1.5E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.9E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 1.2E-55 T 16-09-2016 Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 SUPERFAMILY SSF51735 9 247 3.9E-75 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PANTHER PTHR24322 157 187 7.9E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 PANTHER PTHR24322 14 141 7.9E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04930 a1142f7fe20a6afb656d97e169517aab 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 44.096 T 16-09-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 5.8E-33 T 16-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 SUPERFAMILY SSF53738 163 260 1.69E-26 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 PANTHER PTHR22573:SF15 2 452 8.8E-149 T 16-09-2016 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Gene3D G3DSA:3.40.120.10 4 158 5.2E-41 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 SUPERFAMILY SSF53738 4 185 4.32E-44 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 447 2.0E-12 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 2.4E-11 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 2.4E-11 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.4E-11 T 16-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 9.4E-18 T 16-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 SUPERFAMILY SSF53738 263 369 1.29E-30 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Gene3D G3DSA:3.40.120.10 181 255 2.8E-23 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 6.1E-169 T 16-09-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 SUPERFAMILY SSF55957 364 452 4.45E-21 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 8.8E-38 T 16-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 PANTHER PTHR22573 2 452 8.8E-149 T 16-09-2016 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Gene3D G3DSA:3.40.120.10 256 372 3.3E-33 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19965 f99dad61f696876ba73a747dc86ed95a 452 Gene3D G3DSA:3.30.310.50 375 450 4.1E-18 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS04985 327c403ce4cf3a63d307cb39716d3518 213 PANTHER PTHR35802 3 210 7.9E-12 T 16-09-2016 Spa2297_RS04985 327c403ce4cf3a63d307cb39716d3518 213 SUPERFAMILY SSF50475 11 193 5.3E-27 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04985 327c403ce4cf3a63d307cb39716d3518 213 Pfam PF04299 Putative FMN-binding domain 10 168 1.2E-23 T 16-09-2016 IPR007396 Transcriptional regulator PAI 2-type Spa2297_RS04985 327c403ce4cf3a63d307cb39716d3518 213 PANTHER PTHR35802:SF1 3 210 7.9E-12 T 16-09-2016 Spa2297_RS04985 327c403ce4cf3a63d307cb39716d3518 213 Gene3D G3DSA:2.30.110.10 1 207 3.4E-35 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 PANTHER PTHR30385 51 274 9.6E-84 T 16-09-2016 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Gene3D G3DSA:1.10.10.10 149 203 8.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Pfam PF04542 Sigma-70 region 2 80 149 6.3E-19 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 SUPERFAMILY SSF88659 224 273 2.62E-8 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Gene3D G3DSA:1.10.601.10 72 147 3.4E-20 T 16-09-2016 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 74 274 2.4E-70 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 SUPERFAMILY SSF88946 68 150 6.41E-27 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Pfam PF04539 Sigma-70 region 3 160 213 2.6E-8 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Pfam PF04545 Sigma-70, region 4 246 273 1.3E-7 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 Gene3D G3DSA:1.10.10.10 240 273 2.6E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 PANTHER PTHR30385:SF4 51 274 9.6E-84 T 16-09-2016 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 SUPERFAMILY SSF88659 153 228 2.75E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS33505 368da19c2fdc76d1a27b7f971b03fea7 274 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 76 274 4.4E-24 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17130 c1cb5610cf8686c2f235a900bfb47969 240 Gene3D G3DSA:3.40.50.150 58 159 7.5E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17130 c1cb5610cf8686c2f235a900bfb47969 240 Pfam PF13489 Methyltransferase domain 54 161 9.0E-13 T 16-09-2016 Spa2297_RS17130 c1cb5610cf8686c2f235a900bfb47969 240 PANTHER PTHR10108 60 153 7.9E-12 T 16-09-2016 Spa2297_RS17130 c1cb5610cf8686c2f235a900bfb47969 240 SUPERFAMILY SSF53335 54 209 8.29E-20 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17130 c1cb5610cf8686c2f235a900bfb47969 240 PANTHER PTHR10108:SF705 60 153 7.9E-12 T 16-09-2016 Spa2297_RS12635 f5c03fecc1b58dd790ab86a4faab88fb 213 SUPERFAMILY SSF56747 26 94 3.27E-15 T 16-09-2016 Spa2297_RS12635 f5c03fecc1b58dd790ab86a4faab88fb 213 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 1 101 9.7E-20 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 Gene3D G3DSA:1.10.10.10 137 192 1.8E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 Pfam PF03861 ANTAR domain 137 188 1.7E-14 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 Gene3D G3DSA:3.30.450.20 20 122 1.7E-14 T 16-09-2016 Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 SUPERFAMILY SSF55785 20 122 3.06E-13 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 SMART SM01012 133 188 1.4E-13 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS03895 845dc72ab9b5d34bde86c9745d468fa7 216 Pfam PF08447 PAS fold 31 117 5.3E-9 T 16-09-2016 IPR013655 PAS fold-3 GO:0005515 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 Gene3D G3DSA:1.20.1250.20 11 196 4.0E-28 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 SUPERFAMILY SSF103473 244 453 1.44E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 SUPERFAMILY SSF103473 7 197 1.44E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 1.2E-7 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.2E-7 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 1.2E-7 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 PANTHER PTHR23501:SF61 11 409 3.3E-109 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 Gene3D G3DSA:1.20.1250.20 259 444 1.8E-13 T 16-09-2016 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 418 1.8E-74 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 Pfam PF07690 Major Facilitator Superfamily 17 407 1.0E-45 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS26590 47d3a5c139db349431a0d1d2055fe991 455 PANTHER PTHR23501 11 409 3.3E-109 T 16-09-2016 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PANTHER PTHR11751:SF333 121 144 3.0E-19 T 16-09-2016 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PANTHER PTHR11751:SF333 12 78 3.0E-19 T 16-09-2016 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 SMART SM00345 17 75 1.1E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 Gene3D G3DSA:1.10.10.10 10 75 2.9E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 SMART SM00866 87 233 1.6E-10 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 Gene3D G3DSA:3.40.1410.10 76 235 5.5E-22 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 SUPERFAMILY SSF46785 12 79 7.31E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 Pfam PF07702 UTRA domain 109 231 9.9E-15 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 6.7E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 6.7E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PANTHER PTHR11751 121 144 3.0E-19 T 16-09-2016 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 PANTHER PTHR11751 12 78 3.0E-19 T 16-09-2016 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 4.3E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04615 54033e13d8fe95600d9bf7c8b0aae1c2 253 SUPERFAMILY SSF64288 63 236 1.15E-25 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Gene3D G3DSA:1.20.1050.60 710 798 3.9E-28 T 16-09-2016 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 394 1113 2.7E-135 T 16-09-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 SUPERFAMILY SSF48208 703 1093 1.12E-14 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 SUPERFAMILY SSF48208 613 664 1.12E-14 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Gene3D G3DSA:2.60.120.260 73 198 1.7E-17 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Pfam PF00754 F5/8 type C domain 74 188 7.6E-13 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Pfam PF07971 Glycosyl hydrolase family 92 588 1109 1.4E-139 T 16-09-2016 IPR012939 Glycosyl hydrolase family 92 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Gene3D G3DSA:2.70.98.10 383 670 1.2E-73 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Gene3D G3DSA:3.30.2080.10 972 1121 4.5E-57 T 16-09-2016 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 PANTHER PTHR12143 360 1115 5.4E-274 T 16-09-2016 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 SUPERFAMILY SSF49785 74 186 4.11E-15 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 PANTHER PTHR12143:SF19 360 1115 5.4E-274 T 16-09-2016 Spa2297_RS25240 d81f487159888498b05e00bdd0312e8f 1248 Gene3D G3DSA:1.20.1610.10 802 971 3.3E-46 T 16-09-2016 Spa2297_RS25435 c9641e18343320bae92a1db3171a1f88 444 Pfam PF05114 Protein of unknown function (DUF692) 5 269 1.4E-78 T 16-09-2016 IPR007801 Uncharacterised protein family UPF0276 Spa2297_RS25435 c9641e18343320bae92a1db3171a1f88 444 PANTHER PTHR42194 1 444 4.8E-160 T 16-09-2016 Spa2297_RS25435 c9641e18343320bae92a1db3171a1f88 444 Gene3D G3DSA:3.20.20.150 2 273 1.5E-83 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS25435 c9641e18343320bae92a1db3171a1f88 444 PANTHER PTHR42194:SF1 1 444 4.8E-160 T 16-09-2016 Spa2297_RS25435 c9641e18343320bae92a1db3171a1f88 444 SUPERFAMILY SSF51658 22 223 1.14E-9 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Gene3D G3DSA:1.25.10.10 636 745 7.9E-9 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Pfam PF13646 HEAT repeats 826 908 7.5E-12 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Pfam PF13646 HEAT repeats 737 813 3.0E-10 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Pfam PF13646 HEAT repeats 636 721 9.5E-10 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SUPERFAMILY SSF48371 634 908 2.44E-27 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Pfam PF00890 FAD binding domain 15 386 1.3E-36 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 3.7E-8 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 3.7E-8 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Gene3D G3DSA:1.25.10.10 746 908 7.9E-27 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Pfam PF02910 Fumarate reductase flavoprotein C-term 445 559 8.8E-12 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PANTHER PTHR11632 1 582 1.1E-155 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 2.4E-11 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 2.4E-11 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SUPERFAMILY SSF46977 430 557 1.13E-33 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SUPERFAMILY SSF51905 5 267 1.03E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SUPERFAMILY SSF51905 363 410 1.03E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 PANTHER PTHR11632:SF6 1 582 1.1E-155 T 16-09-2016 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 802 832 550.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 865 896 36.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 645 674 130.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 676 710 140.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 834 863 0.48 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 SMART SM00567 E-Z type HEAT repeats 770 799 790.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Gene3D G3DSA:1.20.58.100 415 528 1.9E-34 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Gene3D G3DSA:3.50.50.60 9 284 2.4E-67 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19275 52b60fe2d4a15134a43d838561fe0aff 908 Gene3D G3DSA:3.50.50.60 363 412 2.4E-67 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.959 T 16-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 PANTHER PTHR11758 1 132 7.6E-57 T 16-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 SUPERFAMILY SSF56047 3 132 3.4E-44 T 16-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 Pfam PF00410 Ribosomal protein S8 5 132 1.2E-49 T 16-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 Gene3D G3DSA:3.30.1370.30 2 72 5.8E-28 T 16-09-2016 Spa2297_RS19865 59e3d69edd0bbbbbd147eefbf3b8c703 132 Gene3D G3DSA:3.30.1490.10 76 132 7.5E-29 T 16-09-2016 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 SMART SM00347 26 126 1.8E-13 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.2E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.2E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.2E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.2E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 Pfam PF13463 Winged helix DNA-binding domain 34 99 1.5E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PANTHER PTHR33164 9 150 3.6E-39 T 16-09-2016 Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 SUPERFAMILY SSF46785 6 143 6.5E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 Gene3D G3DSA:1.10.10.10 8 141 9.9E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27900 0fff2f0f8c1150132542066f1d4a64cc 153 PANTHER PTHR33164:SF16 9 150 3.6E-39 T 16-09-2016 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 Gene3D G3DSA:1.10.10.10 6 55 1.0E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 PANTHER PTHR30154:SF28 1 160 6.3E-65 T 16-09-2016 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 SMART SM00344 7 116 5.6E-32 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 9.3E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 SUPERFAMILY SSF46785 6 66 1.49E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 Gene3D G3DSA:3.30.70.920 60 149 3.6E-20 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 PANTHER PTHR30154 1 160 6.3E-65 T 16-09-2016 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 2.6E-16 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.0E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.0E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.0E-14 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS04735 11e41167f69375df8267ce052b95127f 162 SUPERFAMILY SSF54909 69 149 5.09E-14 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 Pfam PF01494 FAD binding domain 290 346 7.9E-7 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 Pfam PF01494 FAD binding domain 5 168 2.3E-8 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 PANTHER PTHR13789 5 371 1.1E-125 T 16-09-2016 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 Gene3D G3DSA:3.50.50.60 275 358 2.2E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 Gene3D G3DSA:3.50.50.60 4 175 2.2E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 SUPERFAMILY SSF51905 5 170 3.6E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 SUPERFAMILY SSF51905 274 365 3.6E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 2.7E-14 T 16-09-2016 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.7E-14 T 16-09-2016 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 2.7E-14 T 16-09-2016 Spa2297_RS02545 ed9252f5a88ec382604eea1d7f4a605b 379 PANTHER PTHR13789:SF174 5 371 1.1E-125 T 16-09-2016 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 8 135 2.6E-49 T 16-09-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 SUPERFAMILY SSF52242 6 134 1.57E-48 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 PANTHER PTHR23408:SF8 1 113 4.0E-63 T 16-09-2016 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 Pfam PF02310 B12 binding domain 8 121 8.8E-23 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 Gene3D G3DSA:3.40.50.280 7 134 1.0E-54 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS20260 bf5c9d672cb8041d3b0a77d916f19901 138 PANTHER PTHR23408 1 113 4.0E-63 T 16-09-2016 Spa2297_RS03795 a5086488859e6c19ac37974c9aabc6d0 309 PANTHER PTHR40761:SF1 1 302 1.0E-91 T 16-09-2016 Spa2297_RS03795 a5086488859e6c19ac37974c9aabc6d0 309 SUPERFAMILY SSF103481 46 121 4.71E-7 T 16-09-2016 Spa2297_RS03795 a5086488859e6c19ac37974c9aabc6d0 309 PANTHER PTHR40761 1 302 1.0E-91 T 16-09-2016 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 Gene3D G3DSA:1.10.10.60 12 58 5.8E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.4E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 SUPERFAMILY SSF46689 13 76 1.49E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 PANTHER PTHR30055 4 207 1.9E-85 T 16-09-2016 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 Gene3D G3DSA:1.10.357.10 61 202 2.1E-38 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 PANTHER PTHR30055:SF74 4 207 1.9E-85 T 16-09-2016 Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 SUPERFAMILY SSF48498 79 204 5.19E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS22900 63f94e1353ae3fd90bef6fb0c304805d 211 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 193 9.7E-18 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 SUPERFAMILY SSF52540 348 728 2.48E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Pfam PF13604 AAA domain 353 531 6.4E-45 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Gene3D G3DSA:1.10.150.20 105 150 4.1E-4 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Pfam PF14490 Helix-hairpin-helix containing domain 155 245 1.3E-31 T 16-09-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 PANTHER PTHR10887:SF284 676 729 3.6E-114 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 19 746 2.0E-201 T 16-09-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 PANTHER PTHR10887 676 729 3.6E-114 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 SMART SM00382 366 563 0.0049 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 15 752 28.919 T 16-09-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 PANTHER PTHR10887 303 607 3.6E-114 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 SUPERFAMILY SSF47781 94 156 1.01E-9 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 PANTHER PTHR10887:SF284 303 607 3.6E-114 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Pfam PF14520 Helix-hairpin-helix domain 105 154 3.1E-6 T 16-09-2016 Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Gene3D G3DSA:3.40.50.300 316 529 4.1E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Gene3D G3DSA:3.40.50.300 662 727 1.5E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11570 ada0e76286a8ea2175059f26bbeb1753 754 Pfam PF13538 UvrD-like helicase C-terminal domain 675 723 1.5E-19 T 16-09-2016 IPR027785 UvrD-like helicase C-terminal domain Spa2297_RS02555 815a0cc267542e0757a0c63fe654b207 284 Gene3D G3DSA:3.40.50.1820 1 278 1.6E-50 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02555 815a0cc267542e0757a0c63fe654b207 284 Pfam PF00561 alpha/beta hydrolase fold 22 260 5.7E-16 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02555 815a0cc267542e0757a0c63fe654b207 284 SUPERFAMILY SSF53474 1 277 1.93E-44 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02555 815a0cc267542e0757a0c63fe654b207 284 PANTHER PTHR10992 190 278 4.2E-32 T 16-09-2016 Spa2297_RS02555 815a0cc267542e0757a0c63fe654b207 284 PANTHER PTHR10992 3 169 4.2E-32 T 16-09-2016 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF55666 474 573 1.96E-24 T 16-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF54211 6 151 3.29E-46 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SMART SM00322 579 643 7.6E-12 T 16-09-2016 IPR004087 K Homology domain GO:0003676 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF54791 576 688 2.13E-19 T 16-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF54211 321 492 1.11E-41 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SMART SM00316 649 723 3.8E-18 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF55666 152 260 3.39E-29 T 16-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Gene3D G3DSA:2.40.50.140 653 720 1.1E-17 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Pfam PF00013 KH domain 583 639 4.8E-11 T 16-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 SUPERFAMILY SSF46915 264 344 4.45E-17 T 16-09-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Pfam PF00575 S1 RNA binding domain 648 718 6.3E-13 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Gene3D G3DSA:3.30.1370.10 579 652 1.3E-23 T 16-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 PANTHER PTHR11252:SF0 17 720 0.0 T 16-09-2016 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Gene3D G3DSA:3.30.230.70 336 570 2.2E-80 T 16-09-2016 IPR027408 PNPase/RNase PH domain Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Gene3D G3DSA:3.30.230.70 8 249 8.4E-86 T 16-09-2016 IPR027408 PNPase/RNase PH domain Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 3.2E-17 T 16-09-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 16-09-2016 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 725 27.034 T 16-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 PIRSF PIRSF005499 7 739 3.0E-283 T 16-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Gene3D G3DSA:1.10.10.400 263 335 2.1E-24 T 16-09-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 1.8E-13 T 16-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 5.8E-18 T 16-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 PANTHER PTHR11252 17 720 0.0 T 16-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS24230 f601d5e7136cf295f9b4f63bff6d8e13 739 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 3.6E-262 T 16-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spa2297_RS21960 6615e93f2e851da71a6bfe2cbcfef192 499 Pfam PF10103 Zinicin-like metallopeptidase 87 439 6.7E-128 T 16-09-2016 IPR018766 Zinicin-like metallopeptidase type 2 Spa2297_RS21960 6615e93f2e851da71a6bfe2cbcfef192 499 PANTHER PTHR39420:SF2 8 475 0.0 T 16-09-2016 Spa2297_RS21960 6615e93f2e851da71a6bfe2cbcfef192 499 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 87 441 8.2E-124 T 16-09-2016 IPR018766 Zinicin-like metallopeptidase type 2 Spa2297_RS21960 6615e93f2e851da71a6bfe2cbcfef192 499 SUPERFAMILY SSF55486 86 441 5.64E-117 T 16-09-2016 Spa2297_RS21960 6615e93f2e851da71a6bfe2cbcfef192 499 PANTHER PTHR39420 8 475 0.0 T 16-09-2016 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 16-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PANTHER PTHR11652 2 116 7.0E-75 T 16-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.5E-44 T 16-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.4E-59 T 16-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 2 123 3.3E-65 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19665 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 8.4E-55 T 16-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 Gene3D G3DSA:3.20.20.70 9 294 1.2E-106 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 4.2E-32 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 4.2E-32 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 4.2E-32 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 4.2E-32 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 292 2.9E-84 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 SMART SM01130 10 295 2.1E-122 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PIRSF PIRSF001365 7 298 2.8E-81 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 16-09-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 16-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 57.448 T 16-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PANTHER PTHR12128 1 293 6.2E-129 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 289 2.9E-86 T 16-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 SUPERFAMILY SSF51569 7 289 5.44E-95 T 16-09-2016 Spa2297_RS24265 514a174e3e2b03181a5639fc41e8706c 299 PANTHER PTHR12128:SF34 1 293 6.2E-129 T 16-09-2016 Spa2297_RS18260 aa5c1cf65d80b54b5b02d7182d14405c 213 SUPERFAMILY SSF52540 1 180 2.74E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18260 aa5c1cf65d80b54b5b02d7182d14405c 213 Gene3D G3DSA:3.40.50.300 2 162 1.8E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18260 aa5c1cf65d80b54b5b02d7182d14405c 213 Pfam PF13671 AAA domain 2 123 7.2E-7 T 16-09-2016 Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 PANTHER PTHR10992 201 258 1.3E-21 T 16-09-2016 Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 PANTHER PTHR10992:SF771 201 258 1.3E-21 T 16-09-2016 Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 PANTHER PTHR10992:SF771 6 179 1.3E-21 T 16-09-2016 Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 Pfam PF12697 Alpha/beta hydrolase family 23 245 1.2E-13 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 SUPERFAMILY SSF53474 3 258 4.69E-32 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 Gene3D G3DSA:3.40.50.1820 1 257 1.0E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS23225 a16486aeb185b9dddb4fa9f8f31c7b8b 258 PANTHER PTHR10992 6 179 1.3E-21 T 16-09-2016 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.8E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 PANTHER PTHR30328 12 199 7.9E-40 T 16-09-2016 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 PANTHER PTHR30328:SF6 12 199 7.9E-40 T 16-09-2016 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 SUPERFAMILY SSF48498 81 195 1.36E-16 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 Gene3D G3DSA:1.10.357.10 10 195 5.4E-35 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.7E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.7E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 Pfam PF13977 Bacterial transcriptional repressor 83 198 9.5E-24 T 16-09-2016 Spa2297_RS23405 f6b355db25a59912ed05822955cbb3c2 203 SUPERFAMILY SSF46689 6 86 1.75E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 SUPERFAMILY SSF56024 384 556 3.45E-56 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 66 737 1.1E-248 T 16-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Pfam PF13089 Polyphosphate kinase N-terminal domain 67 173 5.6E-37 T 16-09-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 PANTHER PTHR30218:SF0 14 744 0.0 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Hamap MF_00347 Polyphosphate kinase [ppk]. 64 740 33.917 T 16-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 PANTHER PTHR30218 14 744 0.0 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Gene3D G3DSA:3.30.870.10 383 558 1.2E-78 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Gene3D G3DSA:3.30.1840.10 169 354 1.7E-71 T 16-09-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Pfam PF02503 Polyphosphate kinase middle domain 182 372 2.2E-65 T 16-09-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Pfam PF13090 Polyphosphate kinase C-terminal domain 388 736 1.1E-152 T 16-09-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 PIRSF PIRSF015589 47 748 2.2E-284 T 16-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 SUPERFAMILY SSF56024 559 740 4.04E-64 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 SUPERFAMILY SSF143724 170 366 9.81E-64 T 16-09-2016 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 SUPERFAMILY SSF140356 64 168 3.66E-36 T 16-09-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Spa2297_RS15450 7033e5c15cf7fc640423a7a1870662d9 749 Gene3D G3DSA:3.30.870.10 559 741 2.6E-70 T 16-09-2016 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 PANTHER PTHR10245 81 292 7.9E-39 T 16-09-2016 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 PANTHER PTHR10245:SF54 81 292 7.9E-39 T 16-09-2016 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 2.5E-25 T 16-09-2016 IPR015035 Domain of unknown function DUF1918 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 SUPERFAMILY SSF50475 169 292 1.83E-23 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 SUPERFAMILY SSF47413 89 151 2.39E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 SUPERFAMILY SSF50118 1 69 1.11E-23 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 SMART SM00530 92 147 8.6E-12 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 Gene3D G3DSA:2.30.110.10 164 294 4.1E-41 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 Gene3D G3DSA:1.10.260.40 88 151 1.4E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 Pfam PF13560 Helix-turn-helix domain 88 147 1.0E-9 T 16-09-2016 Spa2297_RS03985 f81792fcb7adb4c631fcddcd8a3402bc 298 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 171 291 7.6E-25 T 16-09-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 Pfam PF13581 Histidine kinase-like ATPase domain 436 526 4.9E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 SUPERFAMILY SSF81606 209 410 3.92E-10 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 SUPERFAMILY SSF55874 456 544 5.42E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 SMART SM00331 202 412 2.1E-39 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 PANTHER PTHR21021:SF19 167 421 6.3E-55 T 16-09-2016 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 PANTHER PTHR21021 167 421 6.3E-55 T 16-09-2016 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 229 412 6.9E-50 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 Gene3D G3DSA:3.30.450.20 59 165 1.1E-11 T 16-09-2016 Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 SUPERFAMILY SSF55785 72 174 6.93E-8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS15595 525dbe4b0ccc33b7cfbd9916fe28fa97 549 Pfam PF08448 PAS fold 64 166 3.3E-8 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS21360 3a858dbb508af3a731fcd4d618a310e7 227 Pfam PF08044 Domain of unknown function (DUF1707) 17 69 6.9E-21 T 16-09-2016 IPR012551 Protein of unknown function DUF1707 Spa2297_RS21360 3a858dbb508af3a731fcd4d618a310e7 227 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 115 174 5.3E-8 T 16-09-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF Spa2297_RS21360 3a858dbb508af3a731fcd4d618a310e7 227 PANTHER PTHR40763:SF1 2 226 8.4E-112 T 16-09-2016 Spa2297_RS21360 3a858dbb508af3a731fcd4d618a310e7 227 PANTHER PTHR40763 2 226 8.4E-112 T 16-09-2016 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 Pfam PF00085 Thioredoxin 6 105 8.6E-33 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 8.8E-37 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 PIRSF PIRSF000077 2 108 1.5E-43 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 PRINTS PR00421 Thioredoxin family signature 72 83 1.1E-7 T 16-09-2016 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 PRINTS PR00421 Thioredoxin family signature 24 32 1.1E-7 T 16-09-2016 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 PRINTS PR00421 Thioredoxin family signature 32 41 1.1E-7 T 16-09-2016 Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 Gene3D G3DSA:3.40.30.10 5 107 1.9E-37 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 SUPERFAMILY SSF52833 3 108 2.81E-37 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS16530 953f21408b51b66baaf00d97b36bd612 110 PANTHER PTHR10438 6 110 6.4E-39 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Gene3D G3DSA:2.40.110.10 110 206 9.7E-34 T 16-09-2016 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 SUPERFAMILY SSF56645 25 230 5.37E-64 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 PANTHER PTHR10909 3 393 9.6E-170 T 16-09-2016 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 111 194 2.7E-19 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 SUPERFAMILY SSF47203 217 376 6.28E-16 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 374 2.5E-18 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 107 5.6E-11 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Gene3D G3DSA:1.10.540.10 25 108 2.9E-17 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 PANTHER PTHR10909:SF242 3 393 9.6E-170 T 16-09-2016 Spa2297_RS04320 a3bec1358787f785e9a36db684a113d6 393 Gene3D G3DSA:1.20.140.10 207 384 3.1E-26 T 16-09-2016 Spa2297_RS07615 157c9e5743eba892bf7fc61efaa20fce 613 PANTHER PTHR33607 23 612 1.1E-205 T 16-09-2016 Spa2297_RS07615 157c9e5743eba892bf7fc61efaa20fce 613 SUPERFAMILY SSF56219 310 611 3.02E-28 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS07615 157c9e5743eba892bf7fc61efaa20fce 613 Gene3D G3DSA:3.60.10.10 309 611 1.2E-34 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS07615 157c9e5743eba892bf7fc61efaa20fce 613 PANTHER PTHR33607:SF1 23 612 1.1E-205 T 16-09-2016 Spa2297_RS07615 157c9e5743eba892bf7fc61efaa20fce 613 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 312 604 6.9E-9 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS07190 d71bf667d3fafb089b198800846d5c92 172 PANTHER PTHR20935 7 99 4.7E-27 T 16-09-2016 Spa2297_RS07190 d71bf667d3fafb089b198800846d5c92 172 Gene3D G3DSA:3.40.50.1240 4 171 2.4E-55 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS07190 d71bf667d3fafb089b198800846d5c92 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 93 1.3E-10 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS07190 d71bf667d3fafb089b198800846d5c92 172 SMART SM00855 8 119 5.2E-6 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS07190 d71bf667d3fafb089b198800846d5c92 172 SUPERFAMILY SSF53254 6 155 1.81E-26 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 PANTHER PTHR11695 15 304 1.7E-65 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 SMART SM00829 10 301 6.4E-19 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 SUPERFAMILY SSF50129 1 150 8.83E-36 T 16-09-2016 IPR011032 GroES-like Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 8.1E-10 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 Pfam PF13602 Zinc-binding dehydrogenase 183 301 1.1E-13 T 16-09-2016 Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 SUPERFAMILY SSF51735 114 228 3.12E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 Gene3D G3DSA:3.40.50.720 147 232 8.6E-23 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29345 ba59b3d4e27de5cd2455cb2a0b934bad 304 Gene3D G3DSA:3.90.180.10 1 146 7.0E-40 T 16-09-2016 IPR011032 GroES-like Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 Gene3D G3DSA:3.40.50.720 8 172 8.2E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 171 182 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 100 113 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 79 95 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 116 136 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 197 209 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 145 162 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 10 25 3.4E-32 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PANTHER PTHR32092:SF6 6 438 5.9E-259 T 16-09-2016 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 201 407 1.4E-58 T 16-09-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 SUPERFAMILY SSF51735 9 172 3.36E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 Gene3D G3DSA:3.90.110.10 174 431 3.6E-74 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 Pfam PF02056 Family 4 glycosyl hydrolase 10 191 4.2E-56 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 SUPERFAMILY SSF56327 175 432 8.63E-67 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS30900 2348a4a012558d27eb3e2d579c4de485 441 PANTHER PTHR32092 6 438 5.9E-259 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PANTHER PTHR22939 52 491 2.6E-163 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 SUPERFAMILY SSF50494 181 393 2.38E-54 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 SUPERFAMILY SSF50156 381 489 1.58E-16 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 Gene3D G3DSA:2.40.10.10 282 403 1.9E-41 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PANTHER PTHR22939:SF79 52 491 2.6E-163 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 Pfam PF13365 Trypsin-like peptidase domain 207 353 8.6E-35 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 216 228 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 282 306 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 346 363 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 438 450 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 240 260 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 1.7E-47 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 Gene3D G3DSA:2.40.10.10 202 281 7.2E-25 T 16-09-2016 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 Gene3D G3DSA:2.30.42.10 428 491 8.4E-18 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS16135 a2e15aadbca880db3099337a4e5430a1 496 Pfam PF13180 PDZ domain 401 489 4.1E-25 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 PANTHER PTHR24362:SF160 6 395 6.7E-104 T 16-09-2016 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 PANTHER PTHR24362 6 395 6.7E-104 T 16-09-2016 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 SMART SM00220 13 276 1.4E-55 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 Gene3D G3DSA:1.10.510.10 82 276 1.1E-47 T 16-09-2016 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 Gene3D G3DSA:1.25.40.10 338 485 3.2E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 Pfam PF00069 Protein kinase domain 13 273 2.9E-44 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 SUPERFAMILY SSF48452 366 477 1.63E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 Gene3D G3DSA:3.30.200.20 5 81 1.1E-23 T 16-09-2016 Spa2297_RS13475 656bb4b07013b73cb135c5022370a23b 510 SUPERFAMILY SSF56112 6 277 2.7E-75 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS24850 295109010ca3225cf7c0ba74bcf4cb27 153 Pfam PF11292 Protein of unknown function (DUF3093) 8 146 5.5E-44 T 16-09-2016 IPR021443 Protein of unknown function DUF3093 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 SMART SM00642 94 448 5.0E-7 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 SUPERFAMILY SSF81296 2 77 3.8E-14 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PIRSF PIRSF006337 1 579 3.3E-223 T 16-09-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902|UniPathway: UPA00299 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 Gene3D G3DSA:2.60.40.10 1 77 4.4E-22 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357:SF110 321 455 7.1E-117 T 16-09-2016 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357:SF110 483 540 7.1E-117 T 16-09-2016 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357:SF110 1 300 7.1E-117 T 16-09-2016 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 SUPERFAMILY SSF51445 79 505 3.48E-100 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357 1 300 7.1E-117 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 Pfam PF11941 Domain of unknown function (DUF3459) 490 577 3.5E-16 T 16-09-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 Gene3D G3DSA:3.20.20.80 94 427 4.4E-75 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 Gene3D G3DSA:3.20.20.80 470 504 4.4E-75 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 Pfam PF00128 Alpha amylase, catalytic domain 109 191 6.5E-10 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357 321 455 7.1E-117 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 PANTHER PTHR10357 483 540 7.1E-117 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25635 0bdca4e501c423c5b9e4c2773d377003 581 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 1 543 2.2E-230 T 16-09-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902|UniPathway: UPA00299 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 Gene3D G3DSA:3.40.30.10 19 146 1.5E-33 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 Gene3D G3DSA:1.50.10.10 189 319 7.3E-17 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 PANTHER PTHR12145:SF11 1 673 1.1E-267 T 16-09-2016 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 SUPERFAMILY SSF52833 3 126 1.2E-29 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 PANTHER PTHR12145 1 673 1.1E-267 T 16-09-2016 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 PIRSF PIRSF006402 1 674 5.1E-206 T 16-09-2016 IPR024705 Spermatogenesis-associated protein 20 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 SUPERFAMILY SSF48208 188 534 1.08E-69 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS21055 99b99ee643ed6a9f365cc805339c7935 675 Pfam PF03190 Protein of unknown function, DUF255 2 162 2.9E-75 T 16-09-2016 IPR004879 Domain of unknown function DUF255 Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 PANTHER PTHR24220 6 229 1.0E-99 T 16-09-2016 Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 SUPERFAMILY SSF52540 4 218 1.2E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 Pfam PF00005 ABC transporter 20 159 9.9E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 Gene3D G3DSA:3.40.50.300 2 220 2.1E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 PANTHER PTHR24220:SF160 6 229 1.0E-99 T 16-09-2016 Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 SMART SM00382 29 215 1.3E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17660 8fae417f6fb690bdeb00ad3e31502908 304 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 Gene3D G3DSA:3.40.50.2300 57 181 6.8E-33 T 16-09-2016 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 Pfam PF13377 Periplasmic binding protein-like domain 177 337 1.2E-37 T 16-09-2016 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 SUPERFAMILY SSF53822 80 336 3.93E-68 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 SUPERFAMILY SSF47413 5 64 4.22E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 Gene3D G3DSA:3.40.50.2300 182 318 3.0E-52 T 16-09-2016 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 9.1E-17 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 SMART SM00354 6 76 1.3E-27 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 PANTHER PTHR30146 5 337 2.6E-139 T 16-09-2016 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 Gene3D G3DSA:1.10.260.40 5 56 4.6E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01070 921dca1bae606ab4cd4669d5ccf47c3f 337 PANTHER PTHR30146:SF48 5 337 2.6E-139 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 Pfam PF00501 AMP-binding enzyme 126 479 1.5E-69 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 SUPERFAMILY SSF56801 96 479 9.55E-92 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 PANTHER PTHR24095:SF137 43 479 1.1E-110 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 Gene3D G3DSA:3.40.50.980 282 433 1.8E-42 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 ProSitePatterns PS00455 Putative AMP-binding domain signature. 271 282 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 Gene3D G3DSA:2.30.38.10 440 479 1.5E-7 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 Gene3D G3DSA:3.40.50.980 119 281 8.1E-48 T 16-09-2016 Spa2297_RS32640 18a3e8f4a0e9b3b883f6ee39f3fb6560 479 PANTHER PTHR24095 43 479 1.1E-110 T 16-09-2016 Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 Gene3D G3DSA:3.40.50.1820 4 290 9.3E-49 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 PANTHER PTHR11731:SF134 23 287 6.3E-19 T 16-09-2016 Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 38 250 1.2E-68 T 16-09-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 SUPERFAMILY SSF53474 128 333 4.36E-39 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 PANTHER PTHR11731 23 287 6.3E-19 T 16-09-2016 Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 Pfam PF10503 Esterase PHB depolymerase 41 238 4.8E-38 T 16-09-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 Spa2297_RS03240 716c7a6c67b0370e7d53d8b17047cd45 501 SUPERFAMILY SSF53474 14 125 2.63E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 300 319 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 471 486 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 143 161 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 411 429 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 161 180 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 270 286 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 69 94 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 435 453 6.0E-68 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 SUPERFAMILY SSF56235 39 591 8.49E-152 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 583 2.4E-122 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PANTHER PTHR11686 1 601 6.9E-298 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 Pfam PF01019 Gamma-glutamyltranspeptidase 62 590 7.6E-154 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26725 6f94a06cc3bcf555efd2cc8cf13dc86e 601 PANTHER PTHR11686:SF27 1 601 6.9E-298 T 16-09-2016 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 Gene3D G3DSA:3.20.20.80 48 311 1.1E-70 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 SUPERFAMILY SSF51445 48 287 3.74E-62 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 Pfam PF00704 Glycosyl hydrolases family 18 77 241 1.8E-16 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 PANTHER PTHR11177:SF203 111 208 3.4E-17 T 16-09-2016 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 PIRSF PIRSF001103 1 313 1.1E-141 T 16-09-2016 IPR016289 Endo-beta-N-acetylglucosaminidase GO:0005576|GO:0033925 KEGG: 00511+3.2.1.96 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 ProSitePatterns PS01095 Chitinases family 18 active site. 166 174 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS24970 14ddab3cde11c4390450113a7d8bc2ea 313 PANTHER PTHR11177 111 208 3.4E-17 T 16-09-2016 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 SMART SM00388 266 327 6.2E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 Pfam PF00672 HAMP domain 192 261 3.7E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PANTHER PTHR24423 205 476 2.2E-129 T 16-09-2016 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PANTHER PTHR24423:SF399 61 135 2.2E-129 T 16-09-2016 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 SMART SM00387 367 476 4.0E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 Gene3D G3DSA:1.10.287.130 258 314 6.1E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 5.1E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 5.1E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 5.1E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 5.1E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 SUPERFAMILY SSF55874 317 475 4.32E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 SMART SM00304 211 265 1.2E-5 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PANTHER PTHR24423 61 135 2.2E-129 T 16-09-2016 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 SUPERFAMILY SSF47384 249 328 1.1E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 475 1.2E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 Gene3D G3DSA:3.30.565.10 315 475 3.6E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 267 327 1.8E-9 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS22850 3f6d889cb4360bcb492bef77f935867c 476 PANTHER PTHR24423:SF399 205 476 2.2E-129 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 SUPERFAMILY SSF53187 361 449 5.71E-54 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 SUPERFAMILY SSF53187 6 199 5.71E-54 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 Pfam PF01546 Peptidase family M20/M25/M40 86 439 1.4E-35 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 PANTHER PTHR11014:SF15 4 451 3.7E-133 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 Pfam PF07687 Peptidase dimerisation domain 204 347 8.5E-14 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 Gene3D G3DSA:3.30.70.360 199 356 1.3E-36 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 Gene3D G3DSA:3.40.630.10 360 449 1.6E-61 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 Gene3D G3DSA:3.40.630.10 5 193 1.6E-61 T 16-09-2016 Spa2297_RS03560 570d495c62e36236f76fdbf3dc3b0fc5 451 PANTHER PTHR11014 4 451 3.7E-133 T 16-09-2016 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 SUPERFAMILY SSF55874 604 689 7.52E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 SUPERFAMILY SSF55781 161 311 8.07E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 SUPERFAMILY SSF81606 343 556 6.15E-10 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 Gene3D G3DSA:3.30.450.20 13 121 4.0E-9 T 16-09-2016 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 PANTHER PTHR21021 248 567 1.0E-64 T 16-09-2016 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 SMART SM00331 327 558 3.0E-33 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 SUPERFAMILY SSF55785 15 119 3.56E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 PANTHER PTHR21021:SF19 248 567 1.0E-64 T 16-09-2016 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 Gene3D G3DSA:3.30.450.40 144 302 1.1E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 Pfam PF13581 Histidine kinase-like ATPase domain 584 692 4.2E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 356 558 1.9E-50 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16960 b664c2f1397433720f5cf4cede32ceab 716 Pfam PF13185 GAF domain 159 299 1.3E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 PANTHER PTHR11751 8 403 4.9E-184 T 16-09-2016 Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 PANTHER PTHR11751:SF303 8 403 4.9E-184 T 16-09-2016 Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 Gene3D G3DSA:3.90.1150.10 279 400 9.2E-40 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 SUPERFAMILY SSF53383 6 399 7.98E-95 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 Pfam PF00155 Aminotransferase class I and II 34 393 1.6E-52 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS21100 09236de3a040df227f656d1951cd7197 403 Gene3D G3DSA:3.40.640.10 51 278 1.8E-66 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 Pfam PF07690 Major Facilitator Superfamily 36 428 8.8E-48 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 Gene3D G3DSA:1.20.1250.20 491 513 1.3E-21 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 Gene3D G3DSA:1.20.1250.20 284 439 1.3E-21 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 SUPERFAMILY SSF103473 266 438 1.96E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 SUPERFAMILY SSF103473 490 518 1.96E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 SUPERFAMILY SSF103473 1 214 1.96E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 PANTHER PTHR23501 5 516 1.3E-152 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 34 58 7.8E-5 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 419 438 7.8E-5 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 145 7.8E-5 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 PANTHER PTHR23501:SF14 5 516 1.3E-152 T 16-09-2016 Spa2297_RS31145 73affbd9ec95c2209182057aa84722c7 533 Gene3D G3DSA:1.20.1250.20 26 210 1.0E-35 T 16-09-2016 Spa2297_RS28730 4d990a94458971d36172160e76a45b5e 298 Pfam PF00950 ABC 3 transport family 11 264 1.7E-61 T 16-09-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 Spa2297_RS28730 4d990a94458971d36172160e76a45b5e 298 SUPERFAMILY SSF81345 4 261 1.57E-32 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS28730 4d990a94458971d36172160e76a45b5e 298 PANTHER PTHR30477:SF13 1 276 6.5E-95 T 16-09-2016 Spa2297_RS28730 4d990a94458971d36172160e76a45b5e 298 PANTHER PTHR30477 1 276 6.5E-95 T 16-09-2016 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 Gene3D G3DSA:3.20.20.30 28 128 7.6E-12 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 Gene3D G3DSA:3.20.20.30 142 288 4.0E-13 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 SUPERFAMILY SSF51679 27 272 1.57E-33 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 Pfam PF00296 Luciferase-like monooxygenase 29 128 2.2E-11 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 Pfam PF00296 Luciferase-like monooxygenase 142 264 1.4E-7 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12215 0c27ef603f3368d747356530c71669fc 290 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 288 4.0E-117 T 16-09-2016 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 SUPERFAMILY SSF55781 9 190 6.32E-28 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 SMART SM00065 24 187 1.9E-20 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 Pfam PF07730 Histidine kinase 194 261 1.6E-17 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 SUPERFAMILY SSF55874 265 390 2.1E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 PANTHER PTHR24421 168 390 1.7E-47 T 16-09-2016 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 Gene3D G3DSA:3.30.565.10 277 390 9.8E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 Gene3D G3DSA:3.30.450.40 18 185 5.6E-28 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 SMART SM00387 298 392 7.9E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 Pfam PF13185 GAF domain 23 177 6.2E-19 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 390 3.9E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 3.2E-6 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 3.2E-6 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS07155 006e4ded6496eb0800685b585622bee2 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 371 3.2E-6 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 SUPERFAMILY SSF46785 1 85 2.55E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 PANTHER PTHR30419:SF6 1 290 2.2E-163 T 16-09-2016 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 PANTHER PTHR30419 1 290 2.2E-163 T 16-09-2016 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-21 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 SUPERFAMILY SSF53850 89 290 2.78E-39 T 16-09-2016 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 Gene3D G3DSA:3.40.190.10 90 173 5.8E-16 T 16-09-2016 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.6E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.6E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.6E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 Gene3D G3DSA:3.40.190.10 174 260 8.4E-16 T 16-09-2016 Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 Gene3D G3DSA:1.10.10.10 1 86 1.8E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02335 3f1c2cd760f20c52178c639ebc4d8484 294 Pfam PF03466 LysR substrate binding domain 88 290 1.5E-43 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 2.6E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 2.6E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 2.6E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 2.6E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SUPERFAMILY SSF55874 290 449 1.96E-31 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PANTHER PTHR24423:SF399 178 450 4.7E-135 T 16-09-2016 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PANTHER PTHR24423:SF399 42 75 4.7E-135 T 16-09-2016 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 Gene3D G3DSA:1.10.287.130 227 286 4.3E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SUPERFAMILY SSF47384 220 300 3.34E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SMART SM00304 184 236 1.2E-13 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 298 3.2E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 449 7.6E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PANTHER PTHR24423 42 75 4.7E-135 T 16-09-2016 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 PANTHER PTHR24423 178 450 4.7E-135 T 16-09-2016 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SMART SM00388 237 300 2.2E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SMART SM00387 341 450 1.2E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 Gene3D G3DSA:3.30.565.10 287 449 1.3E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 SUPERFAMILY SSF158472 185 233 1.22E-8 T 16-09-2016 Spa2297_RS08820 7d2a791a6487ad71227f29dbb16a8be0 450 Pfam PF00672 HAMP domain 164 233 3.4E-17 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 SUPERFAMILY SSF52540 338 577 2.15E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 Pfam PF00664 ABC transporter transmembrane region 35 301 2.8E-25 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 Gene3D G3DSA:3.40.50.300 343 573 2.5E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 SUPERFAMILY SSF90123 21 332 4.05E-55 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 Gene3D G3DSA:1.20.1560.10 21 332 2.1E-55 T 16-09-2016 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 PANTHER PTHR24221:SF221 9 587 0.0 T 16-09-2016 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 SMART SM00382 368 554 5.7E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 PANTHER PTHR24221 9 587 0.0 T 16-09-2016 Spa2297_RS23040 0a42e04b1c05cc1ddc546a60e5123498 589 Pfam PF00005 ABC transporter 359 508 1.3E-22 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 Pfam PF00005 ABC transporter 24 170 3.4E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 PANTHER PTHR24220 8 262 2.4E-141 T 16-09-2016 Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 Gene3D G3DSA:3.40.50.300 4 240 9.2E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 PANTHER PTHR24220:SF438 8 262 2.4E-141 T 16-09-2016 Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 SUPERFAMILY SSF52540 4 233 1.57E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS01690 b3d2c9d9409727c39d870b3b062531e9 270 SMART SM00382 31 220 1.0E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26860 d864a7f91150910b2ee58b7785d5cea0 314 Gene3D G3DSA:1.10.3720.10 104 306 3.0E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26860 d864a7f91150910b2ee58b7785d5cea0 314 PANTHER PTHR30465:SF2 25 310 2.9E-94 T 16-09-2016 Spa2297_RS26860 d864a7f91150910b2ee58b7785d5cea0 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 299 1.1E-26 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26860 d864a7f91150910b2ee58b7785d5cea0 314 SUPERFAMILY SSF161098 104 292 3.4E-25 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26860 d864a7f91150910b2ee58b7785d5cea0 314 PANTHER PTHR30465 25 310 2.9E-94 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 SUPERFAMILY SSF49503 202 298 2.27E-40 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 SUPERFAMILY SSF49503 134 157 2.27E-40 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 225 273 - T 16-09-2016 IPR001505 Copper centre Cu(A) GO:0005507 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 Gene3D G3DSA:1.10.287.90 41 124 1.3E-13 T 16-09-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 Gene3D G3DSA:2.60.40.420 136 290 5.3E-41 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PANTHER PTHR22888 1 180 1.0E-108 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 288 1.0E-46 T 16-09-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 208 279 8.6E-18 T 16-09-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PANTHER PTHR22888 205 297 1.0E-108 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PRINTS PR01166 Cytochrome c oxidase subunit II signature 244 261 9.3E-14 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PRINTS PR01166 Cytochrome c oxidase subunit II signature 224 244 9.3E-14 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 9.3E-14 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 9.3E-14 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PRINTS PR01166 Cytochrome c oxidase subunit II signature 262 279 9.3E-14 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PANTHER PTHR22888:SF2 1 180 1.0E-108 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 PANTHER PTHR22888:SF2 205 297 1.0E-108 T 16-09-2016 Spa2297_RS08890 f1fc0513c263148536a2bf4b947b21a3 319 SUPERFAMILY SSF81464 26 124 9.65E-18 T 16-09-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 SMART SM00471 66 229 8.7E-13 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 Pfam PF01966 HD domain 70 218 7.2E-16 T 16-09-2016 IPR006674 HD domain Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 4 421 31.334 T 16-09-2016 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 28 421 2.3E-74 T 16-09-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 Pfam PF13286 Phosphohydrolase-associated domain 328 419 2.5E-21 T 16-09-2016 IPR026875 Phosphohydrolase-associated domain Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 Gene3D G3DSA:1.10.3410.10 216 348 2.1E-21 T 16-09-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 Gene3D G3DSA:1.10.3210.10 17 215 7.7E-66 T 16-09-2016 IPR006674 HD domain Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 SUPERFAMILY SSF109604 22 169 4.04E-59 T 16-09-2016 Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 SUPERFAMILY SSF109604 200 413 4.04E-59 T 16-09-2016 Spa2297_RS10425 563be2e249ba402ca69f488f45b1f345 424 PANTHER PTHR11373 23 169 4.2E-43 T 16-09-2016 Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Pfam PF03990 Domain of unknown function (DUF348) 89 128 2.5E-11 T 16-09-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Pfam PF03990 Domain of unknown function (DUF348) 148 174 1.5E-6 T 16-09-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Pfam PF03990 Domain of unknown function (DUF348) 203 241 8.0E-10 T 16-09-2016 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Gene3D G3DSA:1.10.530.10 320 419 8.8E-29 T 16-09-2016 Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Pfam PF06737 Transglycosylase-like domain 342 415 2.6E-23 T 16-09-2016 IPR010618 Transglycosylase-like Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 Pfam PF07501 G5 domain 260 332 1.8E-20 T 16-09-2016 IPR011098 G5 domain Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 SUPERFAMILY SSF53955 342 418 8.28E-23 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS13700 d9780cbfb619271e3598bb1607cd123a 421 SMART SM01208 256 334 3.6E-23 T 16-09-2016 IPR011098 G5 domain Spa2297_RS05175 b0ce971885389458a5c904114977ec05 131 Gene3D G3DSA:1.10.10.10 56 107 9.6E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05175 b0ce971885389458a5c904114977ec05 131 Pfam PF05331 Protein of unknown function (DUF742) 15 131 6.2E-40 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS05175 b0ce971885389458a5c904114977ec05 131 PANTHER PTHR36221 1 131 3.9E-39 T 16-09-2016 Spa2297_RS13200 f34a9b411537bcfc1d53fef544b7d780 351 Gene3D G3DSA:3.90.550.10 10 242 2.8E-38 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13200 f34a9b411537bcfc1d53fef544b7d780 351 Pfam PF00535 Glycosyl transferase family 2 13 177 1.1E-22 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS13200 f34a9b411537bcfc1d53fef544b7d780 351 PANTHER PTHR22916 10 220 4.2E-33 T 16-09-2016 Spa2297_RS13200 f34a9b411537bcfc1d53fef544b7d780 351 SUPERFAMILY SSF53448 9 251 2.44E-44 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 155 440 8.4E-114 T 16-09-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 Gene3D G3DSA:1.10.645.10 267 324 1.1E-23 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 Gene3D G3DSA:1.10.645.10 29 265 1.4E-45 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 Gene3D G3DSA:1.10.645.10 368 433 1.1E-23 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 PANTHER PTHR11993:SF28 352 435 3.0E-232 T 16-09-2016 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 SUPERFAMILY SSF56762 48 440 8.63E-123 T 16-09-2016 IPR029014 NiFe hydrogenase-like Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 PANTHER PTHR11993 8 335 3.0E-232 T 16-09-2016 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 PANTHER PTHR11993 352 435 3.0E-232 T 16-09-2016 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 75 86 - T 16-09-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 34 440 47.095 T 16-09-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 PANTHER PTHR11993:SF28 8 335 3.0E-232 T 16-09-2016 Spa2297_RS19210 c09836c3c2695cbf86649a3521625293 440 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 38 440 3.3E-175 T 16-09-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.3E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.3E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.3E-12 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 255 5.9E-53 T 16-09-2016 Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PANTHER PTHR24322:SF378 163 195 1.6E-47 T 16-09-2016 Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PANTHER PTHR24322 163 195 1.6E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 Gene3D G3DSA:3.40.50.720 11 257 2.6E-77 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PANTHER PTHR24322 20 147 1.6E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 9.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 PANTHER PTHR24322:SF378 20 147 1.6E-47 T 16-09-2016 Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 SUPERFAMILY SSF51735 11 257 2.28E-73 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31560 cce420a8dac40babe6b852c91fd910c0 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 SUPERFAMILY SSF51735 6 145 6.84E-17 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 Gene3D G3DSA:3.40.50.720 5 106 8.0E-10 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 Gene3D G3DSA:3.30.360.10 118 233 7.8E-27 T 16-09-2016 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 106 2.3E-11 T 16-09-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 Pfam PF01958 Domain of unknown function DUF108 165 251 1.4E-23 T 16-09-2016 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21|UniPathway: UPA00253 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 PANTHER PTHR31873 2 266 9.1E-38 T 16-09-2016 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 SUPERFAMILY SSF55347 118 234 3.6E-19 T 16-09-2016 Spa2297_RS11980 c84f567476030a388d534d14b2489393 266 PIRSF PIRSF005227 3 263 3.7E-62 T 16-09-2016 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21|UniPathway: UPA00253 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 PANTHER PTHR24096:SF206 1 481 6.9E-222 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Gene3D G3DSA:3.40.50.980 5 141 1.5E-23 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Gene3D G3DSA:3.40.50.980 142 302 2.8E-33 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Pfam PF13193 AMP-binding enzyme C-terminal domain 396 472 1.1E-19 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 ProSitePatterns PS00455 Putative AMP-binding domain signature. 136 147 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 SUPERFAMILY SSF56801 13 479 6.41E-128 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Pfam PF00501 AMP-binding enzyme 12 386 1.3E-80 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 PANTHER PTHR24096 1 481 6.9E-222 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Gene3D G3DSA:3.30.300.30 383 479 1.6E-30 T 16-09-2016 Spa2297_RS10320 9dd5aacc67ed9a3da0f1798ed5b08df0 481 Gene3D G3DSA:2.30.38.10 303 380 2.1E-28 T 16-09-2016 Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 PANTHER PTHR33993:SF3 3 267 2.8E-102 T 16-09-2016 Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 SUPERFAMILY SSF54593 150 260 3.22E-6 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 PANTHER PTHR33993 3 267 2.8E-102 T 16-09-2016 Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 Gene3D G3DSA:3.10.180.10 24 134 4.5E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 Gene3D G3DSA:3.10.180.10 149 262 1.9E-12 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS01980 0af9a3f58fd7296822a3ac645ca001ca 267 SUPERFAMILY SSF54593 25 145 2.15E-18 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS21050 ba5949703cf46ee3215c8a4e6a847ffc 188 PANTHER PTHR35400 31 188 4.7E-13 T 16-09-2016 Spa2297_RS21050 ba5949703cf46ee3215c8a4e6a847ffc 188 Pfam PF05685 Putative restriction endonuclease 18 144 1.9E-20 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS21050 ba5949703cf46ee3215c8a4e6a847ffc 188 SUPERFAMILY SSF52980 11 146 1.39E-18 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS21050 ba5949703cf46ee3215c8a4e6a847ffc 188 Gene3D G3DSA:3.90.1570.10 13 148 8.0E-19 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS21050 ba5949703cf46ee3215c8a4e6a847ffc 188 PANTHER PTHR35400:SF1 31 188 4.7E-13 T 16-09-2016 Spa2297_RS19240 ac4036c53519fa01600f96a28040c46d 285 PANTHER PTHR33269:SF1 15 210 4.5E-79 T 16-09-2016 Spa2297_RS19240 ac4036c53519fa01600f96a28040c46d 285 PANTHER PTHR33269 15 210 4.5E-79 T 16-09-2016 Spa2297_RS19240 ac4036c53519fa01600f96a28040c46d 285 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 33 178 9.0E-31 T 16-09-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Spa2297_RS09440 bf4c440300e307ea0416b6868426d900 235 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 27 118 7.1E-23 T 16-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spa2297_RS09440 bf4c440300e307ea0416b6868426d900 235 PANTHER PTHR14239 4 222 2.6E-57 T 16-09-2016 Spa2297_RS09440 bf4c440300e307ea0416b6868426d900 235 SUPERFAMILY SSF51735 27 229 1.59E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09440 bf4c440300e307ea0416b6868426d900 235 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 25 232 3.5E-80 T 16-09-2016 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 Spa2297_RS09440 bf4c440300e307ea0416b6868426d900 235 Gene3D G3DSA:3.40.50.720 27 228 3.4E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00335 630ad203ca9673d7b9cfe2a2496f53f6 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 262 6.4E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00335 630ad203ca9673d7b9cfe2a2496f53f6 273 Gene3D G3DSA:1.10.3720.10 6 263 4.7E-45 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00335 630ad203ca9673d7b9cfe2a2496f53f6 273 PANTHER PTHR32243 1 269 5.3E-126 T 16-09-2016 Spa2297_RS00335 630ad203ca9673d7b9cfe2a2496f53f6 273 PANTHER PTHR32243:SF9 1 269 5.3E-126 T 16-09-2016 Spa2297_RS00335 630ad203ca9673d7b9cfe2a2496f53f6 273 SUPERFAMILY SSF161098 6 270 7.33E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 33 261 39.545 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 33 260 3.4E-80 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 SUPERFAMILY SSF64005 33 256 3.53E-86 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 Gene3D G3DSA:3.40.1180.10 33 261 5.3E-95 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 206 223 - T 16-09-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 Pfam PF01255 Putative undecaprenyl diphosphate synthase 40 260 1.2E-76 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 PANTHER PTHR10291 33 273 3.0E-123 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS10585 b1603799c4978f56378d3ad7ebaaf93d 278 PANTHER PTHR10291:SF0 33 273 3.0E-123 T 16-09-2016 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 PANTHER PTHR11019 136 221 4.5E-13 T 16-09-2016 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 Gene3D G3DSA:1.10.10.60 179 223 6.9E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 SUPERFAMILY SSF46689 180 224 7.53E-5 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 SMART SM00342 143 225 4.5E-16 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 177 221 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 PANTHER PTHR11019:SF126 136 221 4.5E-13 T 16-09-2016 Spa2297_RS25820 fa128abeca83822f4e322fb86cd646fd 226 Pfam PF12833 Helix-turn-helix domain 150 225 1.1E-16 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 Gene3D G3DSA:3.90.180.10 1 146 7.8E-50 T 16-09-2016 IPR011032 GroES-like Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 SUPERFAMILY SSF50129 1 140 3.5E-40 T 16-09-2016 IPR011032 GroES-like Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 PANTHER PTHR11695 15 323 4.1E-157 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 Gene3D G3DSA:3.40.50.720 147 259 5.8E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 Pfam PF00107 Zinc-binding dehydrogenase 151 266 1.5E-29 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 SMART SM00829 10 323 3.6E-49 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.1E-7 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 PANTHER PTHR11695:SF610 15 323 4.1E-157 T 16-09-2016 Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 SUPERFAMILY SSF51735 112 287 9.6E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16850 d2f3973a6b43fbd6c42878773f675752 327 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 3.2E-139 T 16-09-2016 IPR014189 Quinone oxidoreductase PIG3 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 PANTHER PTHR11699 6 474 5.0E-240 T 16-09-2016 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 Gene3D G3DSA:3.40.309.10 264 449 6.7E-65 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 Gene3D G3DSA:3.40.605.10 5 263 2.9E-94 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 PANTHER PTHR11699:SF49 6 474 5.0E-240 T 16-09-2016 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 SUPERFAMILY SSF53720 4 477 6.28E-164 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS03185 643619d2e3af004b3b14ad754aba4773 479 Pfam PF00171 Aldehyde dehydrogenase family 14 472 1.0E-159 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 PANTHER PTHR35794 209 318 9.9E-18 T 16-09-2016 Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.4E-16 T 16-09-2016 IPR019933 DivIVA domain Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 Pfam PF05103 DivIVA protein 3 64 7.4E-14 T 16-09-2016 IPR007793 DivIVA family Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 PANTHER PTHR35794:SF2 1 72 9.9E-18 T 16-09-2016 Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 PANTHER PTHR35794:SF2 209 318 9.9E-18 T 16-09-2016 Spa2297_RS08490 1ffd9a7a854401e17457ce22392b2855 400 PANTHER PTHR35794 1 72 9.9E-18 T 16-09-2016 Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 Pfam PF05593 RHS Repeat 877 908 3.2E-6 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 Pfam PF05593 RHS Repeat 830 866 1.6E-5 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 Pfam PF05593 RHS Repeat 1196 1225 1.6E-5 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 Pfam PF05593 RHS Repeat 725 761 1.2E-4 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 Pfam PF05593 RHS Repeat 662 698 1.1E-11 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 PANTHER PTHR32305 490 1041 7.5E-105 T 16-09-2016 Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 PANTHER PTHR32305:SF6 1120 1401 7.5E-105 T 16-09-2016 Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 830 871 4.6E-6 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 725 764 1.7E-4 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 662 699 2.0E-7 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 620 661 9.7E-4 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1196 1230 2.3E-8 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 872 912 4.9E-7 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 768 806 0.0015 T 16-09-2016 IPR006530 YD repeat Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 PANTHER PTHR32305:SF6 490 1041 7.5E-105 T 16-09-2016 Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 PANTHER PTHR32305 1120 1401 7.5E-105 T 16-09-2016 Spa2297_RS19780 f92c415fbf64091c24444339e13bbcd4 1551 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1325 1398 1.1E-21 T 16-09-2016 IPR022385 Rhs repeat-associated core GO:0097264 Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 SUPERFAMILY SSF56784 5 266 2.07E-58 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 262 4.8E-44 T 16-09-2016 IPR000150 Cof protein GO:0016787 Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 235 8.6E-19 T 16-09-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 PANTHER PTHR10000 1 266 1.8E-73 T 16-09-2016 Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 262 5.6E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 PANTHER PTHR10000:SF8 1 266 1.8E-73 T 16-09-2016 Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 Gene3D G3DSA:3.40.50.1000 4 76 1.3E-47 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS19355 85097c8e6454f9ec493585e3691075d3 266 Gene3D G3DSA:3.40.50.1000 171 266 1.3E-47 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03325 29e26383ebcec4998fa5c8ed4fe20d14 421 Gene3D G3DSA:3.90.1720.10 49 201 4.9E-24 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS03325 29e26383ebcec4998fa5c8ed4fe20d14 421 SUPERFAMILY SSF54001 51 201 2.4E-21 T 16-09-2016 Spa2297_RS03325 29e26383ebcec4998fa5c8ed4fe20d14 421 Pfam PF00877 NlpC/P60 family 67 190 2.0E-12 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS03325 29e26383ebcec4998fa5c8ed4fe20d14 421 Pfam PF10901 Protein of unknown function (DUF2690) 324 375 5.6E-5 T 16-09-2016 IPR021224 Protein of unknown function DUF2690 Spa2297_RS09905 7b9b5adb82e24c2c8fdebb1015d419fd 256 Pfam PF13349 Putative adhesin 122 253 1.6E-8 T 16-09-2016 IPR025164 Putative adhesin Spa2297_RS04980 66a5b3b02dcb138b40567657333cefa7 228 PANTHER PTHR34071 9 225 5.1E-84 T 16-09-2016 Spa2297_RS04980 66a5b3b02dcb138b40567657333cefa7 228 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 33 178 1.3E-49 T 16-09-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Spa2297_RS04980 66a5b3b02dcb138b40567657333cefa7 228 Gene3D G3DSA:2.30.110.10 10 200 1.9E-76 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04980 66a5b3b02dcb138b40567657333cefa7 228 PANTHER PTHR34071:SF2 9 225 5.1E-84 T 16-09-2016 Spa2297_RS04980 66a5b3b02dcb138b40567657333cefa7 228 SUPERFAMILY SSF50475 15 200 2.16E-60 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 Pfam PF00571 CBS domain 220 274 5.1E-5 T 16-09-2016 IPR000644 CBS domain Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 Pfam PF00571 CBS domain 287 336 1.8E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 SUPERFAMILY SSF54631 208 337 4.03E-25 T 16-09-2016 Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 PANTHER PTHR22777:SF7 4 338 1.8E-150 T 16-09-2016 Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 SMART SM00116 288 336 0.078 T 16-09-2016 IPR000644 CBS domain Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 SMART SM00116 228 276 1.3 T 16-09-2016 IPR000644 CBS domain Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 PANTHER PTHR22777 4 338 1.8E-150 T 16-09-2016 Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 Gene3D G3DSA:3.10.580.10 226 335 2.0E-18 T 16-09-2016 Spa2297_RS04565 caa17192d828e0fb9947a9767bd55c2e 340 Pfam PF01595 Domain of unknown function DUF21 8 202 2.4E-39 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS12340 7370fa0113bf9670ea36b1d0f6bd2380 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 69 110 1.1E-5 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS12340 7370fa0113bf9670ea36b1d0f6bd2380 119 Gene3D G3DSA:3.10.180.10 3 117 3.4E-30 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS12340 7370fa0113bf9670ea36b1d0f6bd2380 119 SUPERFAMILY SSF54593 19 118 7.25E-22 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 Pfam PF12802 MarR family 2 48 1.0E-6 T 16-09-2016 Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 PANTHER PTHR18964 46 355 5.2E-83 T 16-09-2016 Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 PANTHER PTHR18964:SF108 46 355 5.2E-83 T 16-09-2016 Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 SUPERFAMILY SSF46785 2 62 1.99E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 Pfam PF00480 ROK family 71 349 7.9E-34 T 16-09-2016 IPR000600 ROK family Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 Gene3D G3DSA:1.10.10.10 1 62 7.9E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 Gene3D G3DSA:3.30.420.40 66 207 4.2E-38 T 16-09-2016 Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 Gene3D G3DSA:3.30.420.40 208 331 1.1E-22 T 16-09-2016 Spa2297_RS04610 1b897a46088e6bccda320d2cdd5ef58d 366 SUPERFAMILY SSF53067 68 354 8.5E-42 T 16-09-2016 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 Gene3D G3DSA:1.10.150.290 194 251 1.6E-29 T 16-09-2016 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 Gene3D G3DSA:3.40.50.150 8 192 2.4E-33 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 Pfam PF13649 Methyltransferase domain 41 136 6.6E-14 T 16-09-2016 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 6 270 47.261 T 16-09-2016 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 PANTHER PTHR10108 1 250 2.1E-101 T 16-09-2016 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 PANTHER PTHR10108:SF808 1 250 2.1E-101 T 16-09-2016 Spa2297_RS13595 e9de3a6d68243318d756ce736b4cb3dc 272 SUPERFAMILY SSF53335 8 221 1.52E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 318 1.8E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 SUPERFAMILY SSF47384 243 320 1.39E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 SMART SM00388 252 319 1.3E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 SMART SM00387 365 476 2.7E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 475 1.4E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PANTHER PTHR24423 2 9 3.0E-71 T 16-09-2016 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PANTHER PTHR24423 178 477 3.0E-71 T 16-09-2016 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 SMART SM00304 184 244 7.6E-6 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 Gene3D G3DSA:1.10.287.130 247 305 1.8E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 Gene3D G3DSA:3.30.565.10 306 477 1.6E-42 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 SUPERFAMILY SSF55874 308 474 4.71E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 Pfam PF00672 HAMP domain 165 240 8.4E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.5E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 1.5E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 1.5E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS25510 372bfe02b5a6de1ab4d256ae4861a2fc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 1.5E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 Pfam PF00005 ABC transporter 269 425 2.1E-16 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 Pfam PF00005 ABC transporter 20 165 2.7E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 SUPERFAMILY SSF52540 244 484 2.21E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 Gene3D G3DSA:3.40.50.300 3 226 4.3E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 Gene3D G3DSA:3.40.50.300 250 490 9.2E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 SMART SM00382 28 213 2.1E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 SUPERFAMILY SSF52540 4 222 1.82E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 PANTHER PTHR24220 5 378 5.0E-192 T 16-09-2016 Spa2297_RS20680 1caf321d8c1dfb235b6a545d747d2466 519 PANTHER PTHR24220:SF239 5 378 5.0E-192 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423 593 827 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 210 1.7E-99 T 16-09-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423:SF562 593 827 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Gene3D G3DSA:3.40.50.300 2 210 1.7E-99 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 SMART SM00388 613 681 4.5E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 SMART SM00387 721 831 1.2E-29 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Gene3D G3DSA:1.20.120.620 383 477 3.2E-17 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Gene3D G3DSA:3.30.565.10 668 831 6.1E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 776 786 4.4E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 815 828 4.4E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 791 809 4.4E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 772 4.4E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423 2 178 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 SUPERFAMILY SSF52402 232 348 5.98E-9 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Pfam PF00512 His Kinase A (phospho-acceptor) domain 614 681 9.6E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423:SF562 221 259 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Pfam PF13493 Domain of unknown function (DUF4118) 383 486 4.8E-23 T 16-09-2016 IPR025201 Sensor protein KdpD, transmembrane domain Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 723 828 1.2E-18 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Gene3D G3DSA:1.10.287.130 605 667 2.0E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Gene3D G3DSA:3.40.50.620 227 346 3.0E-10 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 SUPERFAMILY SSF47384 602 681 4.71E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 SUPERFAMILY SSF55874 671 828 1.44E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423:SF562 2 178 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 PANTHER PTHR24423 221 259 1.0E-122 T 16-09-2016 Spa2297_RS24875 71047d3b90ff6ef24e9763e679f70ff6 848 Pfam PF00582 Universal stress protein family 232 346 5.6E-6 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Pfam PF00108 Thiolase, N-terminal domain 8 266 2.9E-59 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Gene3D G3DSA:3.40.47.10 280 398 9.0E-51 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Gene3D G3DSA:3.40.47.10 152 191 9.0E-51 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Pfam PF02803 Thiolase, C-terminal domain 275 397 5.0E-36 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 6.4E-133 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 PANTHER PTHR18919 3 400 3.3E-165 T 16-09-2016 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Gene3D G3DSA:3.40.47.10 192 278 6.1E-53 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 Gene3D G3DSA:3.40.47.10 7 131 6.1E-53 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 SUPERFAMILY SSF53901 7 273 2.88E-62 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 PANTHER PTHR18919:SF69 3 400 3.3E-165 T 16-09-2016 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 PIRSF PIRSF000429 3 400 8.3E-122 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS25340 afe13a59bca9b710cca70c59c9989ba2 405 SUPERFAMILY SSF53901 277 397 1.22E-38 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS20605 a077740aeebdf2967657c3251fa1c028 293 Gene3D G3DSA:3.40.50.150 125 271 1.5E-7 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20605 a077740aeebdf2967657c3251fa1c028 293 SUPERFAMILY SSF53335 123 272 4.72E-11 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20605 a077740aeebdf2967657c3251fa1c028 293 Pfam PF13578 Methyltransferase domain 128 256 3.6E-18 T 16-09-2016 Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 SMART SM00382 49 235 2.2E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 PANTHER PTHR24220 22 260 4.2E-171 T 16-09-2016 Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 SUPERFAMILY SSF52540 23 239 8.47E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 Gene3D G3DSA:3.40.50.300 23 239 3.6E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 PANTHER PTHR24220:SF484 22 260 4.2E-171 T 16-09-2016 Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13505 79efc9f9b9f1a22f177d6a4e732c3e06 262 Pfam PF00005 ABC transporter 40 186 1.5E-32 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 PANTHER PTHR13501 1 109 9.7E-48 T 16-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 4.2E-45 T 16-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 16-09-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 SUPERFAMILY SSF54843 1 112 2.49E-42 T 16-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 Gene3D G3DSA:3.90.470.10 1 112 2.2E-42 T 16-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 30.303 T 16-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19820 834b48d4e8a89e8ac4766df3f156fb4a 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 1.5E-32 T 16-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 PRINTS PR01576 Peptide deformylase signature 149 178 3.8E-34 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 PRINTS PR01576 Peptide deformylase signature 130 148 3.8E-34 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 PRINTS PR01576 Peptide deformylase signature 56 85 3.8E-34 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 PRINTS PR01576 Peptide deformylase signature 118 129 3.8E-34 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 Hamap MF_00163 Peptide deformylase [def]. 25 191 27.75 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 29 183 3.0E-35 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 Pfam PF01327 Polypeptide deformylase 27 181 3.3E-45 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 PANTHER PTHR10458 23 211 2.9E-55 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 Gene3D G3DSA:3.90.45.10 28 193 1.2E-54 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS19185 0bbf6c889d18f7d20c2c4cbc4cb4fe4f 212 SUPERFAMILY SSF56420 24 185 5.1E-52 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 SUPERFAMILY SSF47413 21 85 7.6E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 SMART SM00530 25 80 1.1E-11 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 PANTHER PTHR10245 8 231 3.1E-81 T 16-09-2016 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 PANTHER PTHR10245:SF54 8 231 3.1E-81 T 16-09-2016 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 Pfam PF13560 Helix-turn-helix domain 24 80 9.0E-9 T 16-09-2016 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 105 227 2.0E-20 T 16-09-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 Gene3D G3DSA:1.10.260.40 22 86 6.3E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 Gene3D G3DSA:2.30.110.10 97 232 2.1E-34 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03900 e754193d79c458621b9aeeb6fb3de53b 244 SUPERFAMILY SSF50475 102 228 1.14E-22 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS11015 f744225fe9284dab91f090872ce45b8f 399 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 353 377 - T 16-09-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 Spa2297_RS11015 f744225fe9284dab91f090872ce45b8f 399 Pfam PF01098 Cell cycle protein 36 394 1.1E-93 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS11015 f744225fe9284dab91f090872ce45b8f 399 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 33 395 2.3E-107 T 16-09-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 Spa2297_RS11015 f744225fe9284dab91f090872ce45b8f 399 PANTHER PTHR30474 12 397 5.4E-160 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS11015 f744225fe9284dab91f090872ce45b8f 399 PANTHER PTHR30474:SF1 12 397 5.4E-160 T 16-09-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 Spa2297_RS25810 c548ccf3befe342047d57802f7fc40fa 344 Pfam PF03631 Virulence factor BrkB 12 266 4.4E-48 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS25810 c548ccf3befe342047d57802f7fc40fa 344 PANTHER PTHR30213:SF2 1 338 1.3E-162 T 16-09-2016 Spa2297_RS25810 c548ccf3befe342047d57802f7fc40fa 344 PANTHER PTHR30213 1 338 1.3E-162 T 16-09-2016 Spa2297_RS25810 c548ccf3befe342047d57802f7fc40fa 344 PIRSF PIRSF035875 1 288 5.8E-48 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 SUPERFAMILY SSF88946 25 109 1.37E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 27 305 2.4E-117 T 16-09-2016 IPR014303 RNA polymerase sigma-70, ECF type Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 PANTHER PTHR30173 1 308 1.2E-148 T 16-09-2016 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 Pfam PF08281 Sigma-70, region 4 125 176 6.9E-13 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 Pfam PF04542 Sigma-70 region 2 30 93 1.5E-12 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 177 3.2E-19 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 SUPERFAMILY SSF88659 93 179 1.01E-12 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 Gene3D G3DSA:1.10.1740.10 25 94 4.2E-12 T 16-09-2016 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 Gene3D G3DSA:3.10.450.50 188 304 3.7E-15 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 SUPERFAMILY SSF54427 190 304 5.63E-16 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 PANTHER PTHR30173:SF25 1 308 1.2E-148 T 16-09-2016 Spa2297_RS11585 f4178cfec6d8b8c2277b11bc3e3b52f5 313 Gene3D G3DSA:1.10.10.10 125 179 5.3E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25490 3ac26a1ce7c9f85fa4a3ad79f1373073 263 SUPERFAMILY SSF53597 46 262 5.56E-37 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS25490 3ac26a1ce7c9f85fa4a3ad79f1373073 263 Pfam PF01872 RibD C-terminal domain 46 242 1.5E-30 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS25490 3ac26a1ce7c9f85fa4a3ad79f1373073 263 Gene3D G3DSA:3.40.430.10 28 262 6.0E-59 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS22840 de8030d79c638c4e7e86585c4b836f03 245 Pfam PF03413 Peptidase propeptide and YPEB domain 76 147 9.3E-9 T 16-09-2016 IPR025711 PepSY domain Spa2297_RS22840 de8030d79c638c4e7e86585c4b836f03 245 Pfam PF03413 Peptidase propeptide and YPEB domain 169 227 3.9E-6 T 16-09-2016 IPR025711 PepSY domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 SUPERFAMILY SSF55785 176 284 3.93E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Pfam PF08448 PAS fold 174 279 6.8E-14 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Gene3D G3DSA:3.30.565.10 348 487 1.2E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PANTHER PTHR24423 159 488 1.9E-178 T 16-09-2016 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Pfam PF12282 Signal transduction histidine kinase 4 147 9.2E-61 T 16-09-2016 IPR022066 Signal transduction histidine kinase Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PANTHER PTHR24423:SF472 4 128 1.9E-178 T 16-09-2016 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PANTHER PTHR24423:SF472 159 488 1.9E-178 T 16-09-2016 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 SUPERFAMILY SSF55874 375 487 7.07E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 8.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 8.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 8.7E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 PANTHER PTHR24423 4 128 1.9E-178 T 16-09-2016 Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 SMART SM00387 385 489 4.7E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Pfam PF07568 Histidine kinase 293 363 2.5E-22 T 16-09-2016 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 487 3.7E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22165 6b777ee6e83053a62d2187728148bc1a 491 Gene3D G3DSA:3.30.450.20 174 276 8.4E-6 T 16-09-2016 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Gene3D G3DSA:2.60.40.1180 620 723 4.3E-33 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 SUPERFAMILY SSF51445 171 614 1.68E-110 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 PANTHER PTHR10357:SF160 41 576 0.0 T 16-09-2016 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 100 722 1.2E-297 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 PANTHER PTHR10357:SF160 592 723 0.0 T 16-09-2016 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 PANTHER PTHR10357 592 723 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 PANTHER PTHR10357 41 576 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 SMART SM00642 241 601 2.4E-8 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Gene3D G3DSA:3.20.20.80 235 608 1.4E-89 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 625 723 1.3E-19 T 16-09-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 SUPERFAMILY SSF51011 620 723 2.16E-30 T 16-09-2016 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 SUPERFAMILY SSF81296 10 105 7.4E-19 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 92 724 43.843 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 PIRSF PIRSF000463 2 724 9.1E-301 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 116 198 4.1E-19 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Pfam PF00128 Alpha amylase, catalytic domain 258 329 2.0E-9 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Gene3D G3DSA:2.60.40.10 9 97 1.7E-16 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS23000 2f9d4ce48d494f6f60860d6576f97ef8 724 Gene3D G3DSA:2.60.40.10 104 212 1.0E-36 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS09145 0966d27d890be9c6aa0087f6daeca7c6 288 SMART SM00943 11 189 4.6E-34 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS09145 0966d27d890be9c6aa0087f6daeca7c6 288 SUPERFAMILY SSF56747 7 207 1.05E-27 T 16-09-2016 Spa2297_RS09145 0966d27d890be9c6aa0087f6daeca7c6 288 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 11 187 4.3E-35 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Pfam PF02559 CarD-like/TRCF domain 500 599 3.5E-31 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF52540 18 367 1.72E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF52540 549 807 1.73E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1103 0.0 T 16-09-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Gene3D G3DSA:3.40.50.300 827 980 1.4E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 PANTHER PTHR14025:SF21 408 1174 0.0 T 16-09-2016 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF141259 493 572 3.01E-18 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF143517 1019 1141 5.49E-32 T 16-09-2016 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SMART SM00487 624 823 1.8E-30 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Gene3D G3DSA:3.30.2060.10 150 224 4.5E-14 T 16-09-2016 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SMART SM01058 499 600 5.7E-47 T 16-09-2016 IPR003711 CarD-like/TRCF domain Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Gene3D G3DSA:3.40.50.300 613 810 2.2E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SMART SM00490 850 934 7.4E-16 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Pfam PF00270 DEAD/DEAH box helicase 649 791 1.3E-16 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF52540 389 482 1.81E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SMART SM00982 1032 1130 7.9E-35 T 16-09-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Pfam PF00271 Helicase conserved C-terminal domain 834 933 9.3E-15 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Pfam PF03461 TRCF domain 1033 1115 1.3E-23 T 16-09-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1125 28.597 T 16-09-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 PANTHER PTHR14025 408 1174 0.0 T 16-09-2016 Spa2297_RS13495 13b36fe935486dbaf946e855ddf6b1aa 1177 SUPERFAMILY SSF52540 806 1014 6.9E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27060 19d3c681ad4006814e80ee888835deae 84 Pfam PF05800 Gas vesicle synthesis protein GvpO 1 79 9.8E-35 T 16-09-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 Spa2297_RS27060 19d3c681ad4006814e80ee888835deae 84 PIRSF PIRSF028743 1 82 1.4E-36 T 16-09-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SMART SM00091 131 195 5.8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SMART SM00091 10 76 0.0099 T 16-09-2016 IPR000014 PAS domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Pfam PF08448 PAS fold 138 256 4.1E-17 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 469 668 9.2E-52 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SUPERFAMILY SSF81606 456 667 3.4E-5 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021:SF19 535 677 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021:SF19 417 519 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021:SF19 251 263 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Pfam PF13581 Histidine kinase-like ATPase domain 682 789 1.0E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SUPERFAMILY SSF55874 709 781 4.75E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021 251 263 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SUPERFAMILY SSF55785 130 247 1.73E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021 535 677 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 PANTHER PTHR21021 417 519 3.6E-48 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Gene3D G3DSA:3.30.450.40 265 419 4.7E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SUPERFAMILY SSF55781 365 421 2.7E-6 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SMART SM00331 442 668 4.7E-30 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Pfam PF13426 PAS domain 22 64 9.8E-4 T 16-09-2016 IPR000014 PAS domain Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Gene3D G3DSA:3.30.450.20 10 65 2.0E-7 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 Gene3D G3DSA:3.30.450.20 130 247 1.8E-12 T 16-09-2016 Spa2297_RS25815 648161f3d073683891cba846a004900d 798 SUPERFAMILY SSF55785 13 114 3.14E-9 T 16-09-2016 IPR000014 PAS domain Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 SMART SM00448 69 199 5.1E-5 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 PANTHER PTHR26402 69 123 2.2E-75 T 16-09-2016 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 SMART SM00331 241 465 1.3E-10 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 Gene3D G3DSA:3.40.50.2300 68 208 8.0E-16 T 16-09-2016 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 SUPERFAMILY SSF52172 67 233 2.56E-11 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 PANTHER PTHR26402:SF517 69 123 2.2E-75 T 16-09-2016 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 270 465 5.5E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 PANTHER PTHR26402 147 452 2.2E-75 T 16-09-2016 Spa2297_RS15190 ae3546fb3e6264d52772eb4a954e325c 473 PANTHER PTHR26402:SF517 147 452 2.2E-75 T 16-09-2016 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 Pfam PF00675 Insulinase (Peptidase family M16) 28 166 2.1E-21 T 16-09-2016 IPR011765 Peptidase M16, N-terminal Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 Gene3D G3DSA:3.30.830.10 21 238 6.1E-60 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 Pfam PF05193 Peptidase M16 inactive domain 187 366 2.0E-30 T 16-09-2016 IPR007863 Peptidase M16, C-terminal Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 SUPERFAMILY SSF63411 251 435 1.0E-26 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 Gene3D G3DSA:3.30.830.10 277 429 8.8E-19 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 PANTHER PTHR11851 20 434 3.7E-137 T 16-09-2016 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 SUPERFAMILY SSF63411 19 225 9.35E-60 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS24745 bc408246613f5e9c7e976561aeeea1c3 449 PANTHER PTHR11851:SF136 20 434 3.7E-137 T 16-09-2016 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 SUPERFAMILY SSF52172 1 116 4.7E-37 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 PANTHER PTHR26402:SF556 1 219 7.4E-81 T 16-09-2016 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 Pfam PF00072 Response regulator receiver domain 1 109 3.2E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 SMART SM00862 144 219 7.5E-27 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 PANTHER PTHR26402 1 219 7.4E-81 T 16-09-2016 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 4.9E-26 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 Gene3D G3DSA:3.40.50.2300 1 117 3.3E-35 T 16-09-2016 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 SUPERFAMILY SSF46894 120 219 1.53E-28 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 SMART SM00448 1 108 4.1E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS28445 6c6c1fdeee8942598779ddaaaaff5417 222 Gene3D G3DSA:1.10.10.10 123 220 5.7E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14825 3fb1b700f4a54036aeebea83a1a021b3 314 PANTHER PTHR10859 13 225 5.9E-40 T 16-09-2016 Spa2297_RS14825 3fb1b700f4a54036aeebea83a1a021b3 314 Gene3D G3DSA:3.90.550.10 35 209 1.5E-10 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS14825 3fb1b700f4a54036aeebea83a1a021b3 314 PANTHER PTHR10859:SF99 13 225 5.9E-40 T 16-09-2016 Spa2297_RS14825 3fb1b700f4a54036aeebea83a1a021b3 314 Pfam PF00535 Glycosyl transferase family 2 36 157 1.4E-9 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS14825 3fb1b700f4a54036aeebea83a1a021b3 314 SUPERFAMILY SSF53448 35 286 8.44E-56 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 SUPERFAMILY SSF81606 182 353 3.4E-12 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 PANTHER PTHR21021 146 392 8.6E-39 T 16-09-2016 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 PANTHER PTHR21021 48 53 8.6E-39 T 16-09-2016 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 195 388 1.2E-40 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 PANTHER PTHR21021:SF22 146 392 8.6E-39 T 16-09-2016 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 SMART SM00331 168 388 1.4E-27 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01805 8dba7180410e0a8df78b9c67666c8940 393 PANTHER PTHR21021:SF22 48 53 8.6E-39 T 16-09-2016 Spa2297_RS00270 3d8937e2d34fe7ed4e17d13b090b5e36 320 PANTHER PTHR32196:SF21 2 320 8.4E-68 T 16-09-2016 Spa2297_RS00270 3d8937e2d34fe7ed4e17d13b090b5e36 320 PANTHER PTHR32196 2 320 8.4E-68 T 16-09-2016 Spa2297_RS00270 3d8937e2d34fe7ed4e17d13b090b5e36 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 311 1.1E-40 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 PANTHER PTHR33164 9 151 3.5E-40 T 16-09-2016 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 SMART SM00347 29 130 3.2E-20 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 SUPERFAMILY SSF46785 7 142 1.63E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 Gene3D G3DSA:1.10.10.10 4 142 1.9E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 Pfam PF01047 MarR family 36 95 2.2E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 8.3E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 8.3E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 8.3E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04085 49d91db868b5f2c2c9e1ef0b66ccbde3 155 PANTHER PTHR33164:SF11 9 151 3.5E-40 T 16-09-2016 Spa2297_RS31835 988d9c35c1e682bed8999afd24398868 481 PIRSF PIRSF000204 2 469 3.2E-210 T 16-09-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Spa2297_RS31835 988d9c35c1e682bed8999afd24398868 481 Gene3D G3DSA:3.40.50.1220 293 467 5.8E-88 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31835 988d9c35c1e682bed8999afd24398868 481 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 465 2.5E-192 T 16-09-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Spa2297_RS31835 988d9c35c1e682bed8999afd24398868 481 PANTHER PTHR10160 12 473 8.3E-234 T 16-09-2016 Spa2297_RS31835 988d9c35c1e682bed8999afd24398868 481 SUPERFAMILY SSF52467 294 468 6.54E-74 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 PANTHER PTHR20852:SF15 1 137 6.1E-261 T 16-09-2016 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 16-09-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 PANTHER PTHR20852 155 469 6.1E-261 T 16-09-2016 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 16-09-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 Gene3D G3DSA:3.10.20.70 5 104 1.1E-33 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 Gene3D G3DSA:3.30.590.10 105 448 5.4E-136 T 16-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 6.8E-137 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 SUPERFAMILY SSF55931 102 468 3.92E-138 T 16-09-2016 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 SUPERFAMILY SSF54368 5 99 5.75E-30 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 2.4E-200 T 16-09-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 PANTHER PTHR20852:SF15 155 469 6.1E-261 T 16-09-2016 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 9.0E-24 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 SMART SM01230 101 378 6.6E-152 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 PANTHER PTHR20852 1 137 6.1E-261 T 16-09-2016 Spa2297_RS09095 ed94bfa75286c09473ffb642cd93939f 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 16-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 Gene3D G3DSA:3.40.50.1980 25 204 7.2E-44 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00690 Adhesin family signature 70 83 4.4E-7 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00690 Adhesin family signature 211 232 4.4E-7 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00690 Adhesin family signature 39 57 4.4E-7 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00690 Adhesin family signature 264 282 4.4E-7 T 16-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PANTHER PTHR30477 143 316 1.4E-72 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PANTHER PTHR30477 1 126 1.4E-72 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 Gene3D G3DSA:3.40.50.1980 205 324 3.1E-35 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PANTHER PTHR30477:SF1 143 316 1.4E-72 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PANTHER PTHR30477:SF1 1 126 1.4E-72 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 Pfam PF01297 Zinc-uptake complex component A periplasmic 42 322 3.1E-73 T 16-09-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 SUPERFAMILY SSF53807 38 323 5.89E-74 T 16-09-2016 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00691 Adhesin B signature 64 82 1.4E-6 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00691 Adhesin B signature 211 228 1.4E-6 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00691 Adhesin B signature 260 277 1.4E-6 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00691 Adhesin B signature 39 60 1.4E-6 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS10565 b00ca16794be3d300e5243b73350b1e1 326 PRINTS PR00691 Adhesin B signature 302 320 1.4E-6 T 16-09-2016 IPR006129 Adhesin B GO:0007155 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 Gene3D G3DSA:2.40.10.10 135 224 2.3E-25 T 16-09-2016 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 Gene3D G3DSA:2.40.10.10 47 128 1.9E-18 T 16-09-2016 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 Pfam PF00089 Trypsin 108 226 1.9E-4 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 SUPERFAMILY SSF50494 50 233 3.93E-24 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 159 176 5.3E-34 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 73 87 5.3E-34 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 202 216 5.3E-34 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 138 158 5.3E-34 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 178 201 5.3E-34 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS29325 037a0a1a7b78c652a2f11e0054ed4b7c 237 PIRSF PIRSF001134 11 237 1.4E-62 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 Gene3D G3DSA:1.10.10.10 7 78 1.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 SUPERFAMILY SSF48008 120 227 4.71E-16 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 Pfam PF07729 FCD domain 121 218 3.8E-10 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 Gene3D G3DSA:1.20.120.530 81 229 2.7E-16 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 PANTHER PTHR11751 13 104 3.0E-18 T 16-09-2016 Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 SUPERFAMILY SSF46785 11 81 1.2E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 1.8E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 SMART SM00895 87 222 1.5E-5 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS17700 f03e5d9ec6475afc15fdaa81ae62ee59 233 SMART SM00345 19 77 2.6E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS20175 a975d3e42236a851401796875b855c46 95 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 22 93 9.9E-15 T 16-09-2016 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal Spa2297_RS20175 a975d3e42236a851401796875b855c46 95 Gene3D G3DSA:1.20.59.10 11 72 1.4E-10 T 16-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS20175 a975d3e42236a851401796875b855c46 95 SMART SM00830 24 92 7.2E-5 T 16-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS20175 a975d3e42236a851401796875b855c46 95 Pfam PF01817 Chorismate mutase type II 24 75 1.8E-8 T 16-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS20175 a975d3e42236a851401796875b855c46 95 SUPERFAMILY SSF48600 20 81 6.72E-11 T 16-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06110 f5fd46ceeb69fdd84f71bc808bf3c090 64 SUPERFAMILY SSF50118 1 61 3.4E-23 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS06110 f5fd46ceeb69fdd84f71bc808bf3c090 64 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 2.2E-27 T 16-09-2016 IPR015035 Domain of unknown function DUF1918 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 SUPERFAMILY SSF46946 132 213 1.7E-21 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 SMART SM01232 132 221 2.3E-29 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 113 5.2E-25 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 SMART SM00898 2 117 6.4E-25 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 SUPERFAMILY SSF81624 2 137 3.92E-29 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 Gene3D G3DSA:1.10.8.50 133 259 3.1E-32 T 16-09-2016 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 SUPERFAMILY SSF57716 211 258 5.7E-10 T 16-09-2016 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 ProSitePatterns PS01242 Zinc finger FPG-type signature. 234 258 - T 16-09-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 212 2.3E-17 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 PANTHER PTHR22993 2 259 7.2E-54 T 16-09-2016 Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 Pfam PF06827 Zinc finger found in FPG and IleRS 234 258 1.0E-8 T 16-09-2016 IPR010663 Zinc finger, FPG/IleRS-type Spa2297_RS17255 dec27269c7fdb561990b42df2c3802e9 259 Gene3D G3DSA:3.20.190.10 2 124 2.6E-26 T 16-09-2016 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.686 T 16-09-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 Gene3D G3DSA:1.10.10.10 1 84 2.8E-36 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 Gene3D G3DSA:3.30.450.40 176 337 6.7E-44 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 1.4E-104 T 16-09-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 SUPERFAMILY SSF55781 71 336 5.89E-58 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 Pfam PF01628 HrcA protein C terminal domain 103 321 2.7E-62 T 16-09-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 PIRSF PIRSF005485 1 338 7.0E-103 T 16-09-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 PANTHER PTHR34824 1 337 2.2E-119 T 16-09-2016 Spa2297_RS10760 06167396a8a9cf12bd7313f35c94a1c5 338 SUPERFAMILY SSF46785 1 82 1.25E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Gene3D G3DSA:2.60.120.260 187 346 8.2E-21 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 SUPERFAMILY SSF49899 362 625 2.95E-65 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Pfam PF00722 Glycosyl hydrolases family 16 402 620 2.6E-32 T 16-09-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 PANTHER PTHR10963 365 584 4.7E-43 T 16-09-2016 Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 SUPERFAMILY SSF49785 186 346 1.63E-20 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Pfam PF00754 F5/8 type C domain 206 325 1.3E-21 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Pfam PF00754 F5/8 type C domain 56 170 1.3E-24 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 SUPERFAMILY SSF49785 51 177 3.26E-28 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Gene3D G3DSA:2.60.120.200 361 625 2.3E-65 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS27550 308ee9889a6255664ff69aecdc617d18 626 Gene3D G3DSA:2.60.120.260 50 178 1.1E-25 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS02625 85d776195452a285a32b4f9b452bf851 185 PANTHER PTHR38011 2 183 9.2E-17 T 16-09-2016 Spa2297_RS02625 85d776195452a285a32b4f9b452bf851 185 Pfam PF01872 RibD C-terminal domain 3 178 1.7E-19 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS02625 85d776195452a285a32b4f9b452bf851 185 SUPERFAMILY SSF53597 1 184 5.89E-25 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS02625 85d776195452a285a32b4f9b452bf851 185 Gene3D G3DSA:3.40.430.10 3 184 1.2E-22 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS02625 85d776195452a285a32b4f9b452bf851 185 PANTHER PTHR38011:SF2 2 183 9.2E-17 T 16-09-2016 Spa2297_RS00040 92a2328cf34f482df8229848b55bd943 154 PANTHER PTHR40787:SF1 1 145 1.4E-84 T 16-09-2016 Spa2297_RS00040 92a2328cf34f482df8229848b55bd943 154 Pfam PF09056 Prokaryotic phospholipase A2 45 149 1.6E-33 T 16-09-2016 IPR015141 Phospholipase A2, prokaryotic/fungal Spa2297_RS00040 92a2328cf34f482df8229848b55bd943 154 PANTHER PTHR40787 1 145 1.4E-84 T 16-09-2016 Spa2297_RS00040 92a2328cf34f482df8229848b55bd943 154 SUPERFAMILY SSF48619 29 149 2.77E-40 T 16-09-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 Spa2297_RS00040 92a2328cf34f482df8229848b55bd943 154 Gene3D G3DSA:1.20.90.10 30 149 8.0E-42 T 16-09-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SUPERFAMILY SSF55781 187 321 4.58E-15 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Pfam PF08447 PAS fold 41 128 1.5E-16 T 16-09-2016 IPR013655 PAS fold-3 GO:0005515 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Pfam PF13185 GAF domain 171 309 2.5E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Gene3D G3DSA:3.30.450.20 27 131 2.5E-16 T 16-09-2016 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SUPERFAMILY SSF81606 356 557 2.75E-11 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 PANTHER PTHR21021:SF19 269 566 2.6E-68 T 16-09-2016 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 370 557 1.4E-47 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SMART SM00331 337 557 5.2E-29 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SMART SM00065 166 319 0.0034 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Pfam PF13581 Histidine kinase-like ATPase domain 576 686 1.6E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Gene3D G3DSA:3.30.565.10 586 689 3.3E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SUPERFAMILY SSF55874 600 686 2.68E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SMART SM00086 92 134 8.8E-9 T 16-09-2016 IPR001610 PAC motif Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 PANTHER PTHR21021 269 566 2.6E-68 T 16-09-2016 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Gene3D G3DSA:3.60.40.10 486 556 1.6E-5 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 Gene3D G3DSA:3.30.450.40 147 323 4.0E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS28925 bbee995cab8a8bcf4df5f1fbc87e134f 696 SUPERFAMILY SSF55785 27 132 1.5E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS22780 18b94df2d4ab86d7e1cd9e00a5e7308e 342 Pfam PF00296 Luciferase-like monooxygenase 1 311 5.5E-56 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS22780 18b94df2d4ab86d7e1cd9e00a5e7308e 342 Gene3D G3DSA:3.20.20.30 1 341 2.9E-91 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS22780 18b94df2d4ab86d7e1cd9e00a5e7308e 342 SUPERFAMILY SSF51679 1 341 3.27E-72 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS22780 18b94df2d4ab86d7e1cd9e00a5e7308e 342 PANTHER PTHR30137:SF8 1 341 2.8E-121 T 16-09-2016 Spa2297_RS22780 18b94df2d4ab86d7e1cd9e00a5e7308e 342 PANTHER PTHR30137 1 341 2.8E-121 T 16-09-2016 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 Pfam PF00892 EamA-like transporter family 12 147 1.3E-9 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 Pfam PF00892 EamA-like transporter family 157 287 1.9E-6 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 PANTHER PTHR22911 5 315 3.6E-143 T 16-09-2016 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 TIGRFAM TIGR00688 rarD: protein RarD 14 263 4.1E-64 T 16-09-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 SUPERFAMILY SSF103481 195 289 1.83E-10 T 16-09-2016 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 SUPERFAMILY SSF103481 52 149 1.02E-12 T 16-09-2016 Spa2297_RS19410 c3320ab480b96822206051a4fc0058f0 333 PANTHER PTHR22911:SF41 5 315 3.6E-143 T 16-09-2016 Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 SUPERFAMILY SSF53335 62 249 1.07E-20 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 PANTHER PTHR10108 29 292 8.5E-35 T 16-09-2016 Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 PANTHER PTHR10108:SF714 29 292 8.5E-35 T 16-09-2016 Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 Pfam PF08421 Putative zinc binding domain 4 65 9.1E-23 T 16-09-2016 IPR013630 Methyltransferase putative zinc binding domain KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 1.1E-63 T 16-09-2016 IPR013691 C-methyltransferase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 Gene3D G3DSA:3.40.50.150 87 255 7.1E-20 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS31760 55d102a04c3a213d1f004f2e392e177f 411 Pfam PF13489 Methyltransferase domain 83 238 1.5E-13 T 16-09-2016 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 PANTHER PTHR31964:SF42 1 158 9.0E-29 T 16-09-2016 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 Pfam PF00582 Universal stress protein family 160 280 2.5E-16 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 Pfam PF00582 Universal stress protein family 1 139 7.1E-25 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 Gene3D G3DSA:3.40.50.620 1 139 9.6E-28 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 Gene3D G3DSA:3.40.50.620 163 280 3.4E-18 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 SUPERFAMILY SSF52402 4 142 6.36E-25 T 16-09-2016 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 PRINTS PR01438 Universal stress protein signature 117 139 1.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 PRINTS PR01438 Universal stress protein signature 99 111 1.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 PRINTS PR01438 Universal stress protein signature 2 20 1.2E-14 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 SUPERFAMILY SSF52402 161 283 3.52E-17 T 16-09-2016 Spa2297_RS03945 b1b6c6059fddbf0d21d53d0a8e10c348 286 PANTHER PTHR31964 1 158 9.0E-29 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Gene3D G3DSA:3.30.70.20 204 239 7.1E-6 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Pfam PF00037 4Fe-4S binding domain 194 211 3.3E-7 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 152 163 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 SUPERFAMILY SSF54292 13 127 6.91E-30 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Gene3D G3DSA:3.30.70.20 142 203 1.3E-12 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 232 284 4.1E-20 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 SUPERFAMILY SSF54862 86 218 1.3E-23 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 PANTHER PTHR11615:SF6 14 285 3.8E-68 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 235 253 - T 16-09-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Gene3D G3DSA:3.10.20.30 13 72 1.2E-7 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 SMART SM00926 230 284 5.2E-18 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 SUPERFAMILY SSF53706 194 285 3.56E-18 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 87 6.8E-22 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 Gene3D G3DSA:2.20.25.90 240 284 3.6E-21 T 16-09-2016 Spa2297_RS27305 a95d7da06656c1d5f059cf032c22f4de 286 PANTHER PTHR11615 14 285 3.8E-68 T 16-09-2016 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 PANTHER PTHR11751 7 111 1.6E-51 T 16-09-2016 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 Gene3D G3DSA:1.10.10.10 7 77 9.6E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 SMART SM00345 15 74 7.2E-21 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 Gene3D G3DSA:1.20.120.530 90 210 3.4E-27 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 SUPERFAMILY SSF48008 92 210 1.86E-25 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 SMART SM00895 95 218 9.6E-19 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 PANTHER PTHR11751:SF342 7 111 1.6E-51 T 16-09-2016 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.3E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.3E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 4.9E-21 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 SUPERFAMILY SSF46785 7 78 1.49E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07205 912eae2bb70c6e6284c202bb016ada3a 230 Pfam PF07729 FCD domain 96 208 1.2E-24 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 SMART SM00382 32 216 9.6E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 PANTHER PTHR24220:SF429 286 329 4.6E-102 T 16-09-2016 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 PANTHER PTHR24220:SF429 9 245 4.6E-102 T 16-09-2016 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 SUPERFAMILY SSF52540 8 228 1.11E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 Pfam PF00005 ABC transporter 24 166 9.3E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 16 311 1.1E-101 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 PANTHER PTHR24220 9 245 4.6E-102 T 16-09-2016 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 Pfam PF13732 Domain of unknown function (DUF4162) 221 309 2.0E-8 T 16-09-2016 IPR025302 Domain of unknown function DUF4162 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 PANTHER PTHR24220 286 329 4.6E-102 T 16-09-2016 Spa2297_RS02805 c22ecd9aa572f856694f093b36989209 337 Gene3D G3DSA:3.40.50.300 6 231 2.0E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 29 51 9.4E-5 T 16-09-2016 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 348 363 9.4E-5 T 16-09-2016 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 PANTHER PTHR13847:SF5 5 416 5.0E-126 T 16-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 PANTHER PTHR13847 5 416 5.0E-126 T 16-09-2016 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Pfam PF01266 FAD dependent oxidoreductase 29 393 1.4E-40 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Gene3D G3DSA:3.30.9.10 128 175 2.4E-4 T 16-09-2016 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Gene3D G3DSA:3.30.9.10 252 354 2.4E-4 T 16-09-2016 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 SUPERFAMILY SSF51905 355 411 7.12E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 SUPERFAMILY SSF51905 28 254 7.12E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Gene3D G3DSA:3.50.50.60 20 109 3.7E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Gene3D G3DSA:3.50.50.60 176 251 3.7E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04675 b829d6dd7c8aa4172bf13ad18bee5db8 440 Gene3D G3DSA:3.50.50.60 355 406 3.7E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Pfam PF16918 Protein kinase G tetratricopeptide repeat 442 748 8.0E-87 T 16-09-2016 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Gene3D G3DSA:1.25.40.10 487 618 9.4E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 SUPERFAMILY SSF48452 507 614 3.57E-14 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Pfam PF00069 Protein kinase domain 58 256 2.4E-26 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 PANTHER PTHR24363 1 337 1.2E-123 T 16-09-2016 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 SUPERFAMILY SSF56112 47 315 6.79E-42 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Gene3D G3DSA:1.10.510.10 144 255 3.5E-21 T 16-09-2016 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Pfam PF16919 Protein kinase G rubredoxin domain 1 54 2.0E-22 T 16-09-2016 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 Gene3D G3DSA:3.30.200.20 49 143 4.3E-14 T 16-09-2016 Spa2297_RS11300 a791cff243434a4dd7cd1e6b80c1f1ef 750 PANTHER PTHR24363:SF0 1 337 1.2E-123 T 16-09-2016 Spa2297_RS19285 977df9135b1f7d10078fe5dd535e483b 310 PANTHER PTHR30151 3 259 4.1E-79 T 16-09-2016 Spa2297_RS19285 977df9135b1f7d10078fe5dd535e483b 310 Gene3D G3DSA:1.10.3720.10 52 246 1.9E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS19285 977df9135b1f7d10078fe5dd535e483b 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 245 2.3E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS19285 977df9135b1f7d10078fe5dd535e483b 310 SUPERFAMILY SSF161098 52 233 3.66E-28 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS19285 977df9135b1f7d10078fe5dd535e483b 310 PANTHER PTHR30151:SF12 3 259 4.1E-79 T 16-09-2016 Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 PANTHER PTHR34390 400 569 1.4E-242 T 16-09-2016 Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 Pfam PF12821 Threonine/Serine exporter, ThrE 415 540 3.6E-16 T 16-09-2016 IPR024528 Threonine/Serine exporter, ThrE Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 Pfam PF06738 Putative threonine/serine exporter 149 392 3.2E-64 T 16-09-2016 IPR010619 Putative threonine/serine exporter Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 PANTHER PTHR34390 95 260 1.4E-242 T 16-09-2016 Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 PANTHER PTHR34390:SF1 95 260 1.4E-242 T 16-09-2016 Spa2297_RS18150 0ce23939a6457548915d693486d06f97 569 PANTHER PTHR34390:SF1 400 569 1.4E-242 T 16-09-2016 Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 Gene3D G3DSA:2.60.120.10 18 216 2.7E-43 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 PANTHER PTHR13903:SF7 5 216 3.8E-68 T 16-09-2016 Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 PIRSF PIRSF006232 4 215 5.2E-36 T 16-09-2016 IPR012093 Pirin Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 Pfam PF02678 Pirin 18 120 2.5E-28 T 16-09-2016 IPR003829 Pirin, N-terminal domain Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 PANTHER PTHR13903 5 216 3.8E-68 T 16-09-2016 IPR012093 Pirin Spa2297_RS10025 aa9c0630202dbd5bb4775bbacf34a8ac 217 SUPERFAMILY SSF51182 16 216 7.47E-48 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS14430 11b12e72c6b4c2dc3aafb510a4733bbe 461 SUPERFAMILY SSF48452 219 436 1.33E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14430 11b12e72c6b4c2dc3aafb510a4733bbe 461 Gene3D G3DSA:1.25.40.10 347 429 4.0E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 Gene3D G3DSA:3.30.200.20 5 116 4.0E-23 T 16-09-2016 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 PANTHER PTHR24362 7 438 1.2E-82 T 16-09-2016 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 SUPERFAMILY SSF56112 405 474 3.1E-80 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 SUPERFAMILY SSF56112 5 276 3.1E-80 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 PANTHER PTHR24362:SF160 7 438 1.2E-82 T 16-09-2016 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 Gene3D G3DSA:1.10.510.10 383 460 7.4E-55 T 16-09-2016 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 Gene3D G3DSA:1.10.510.10 117 271 7.4E-55 T 16-09-2016 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 Pfam PF00069 Protein kinase domain 10 269 4.3E-52 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS12860 e75177fb207cbd6fcbfa1537c0d64fa1 560 SMART SM00220 8 276 7.3E-76 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 Gene3D G3DSA:1.10.357.10 77 212 1.3E-26 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 SUPERFAMILY SSF46689 11 93 3.85E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 PANTHER PTHR30328 2 214 1.9E-82 T 16-09-2016 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 4.2E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 SUPERFAMILY SSF48498 90 215 7.03E-36 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 PANTHER PTHR30328:SF16 2 214 1.9E-82 T 16-09-2016 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 Gene3D G3DSA:1.10.10.60 11 52 4.4E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27665 972266a4ea2bbc6d3327d8fc4cfe78de 221 Gene3D G3DSA:1.10.10.60 53 76 2.3E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.6E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 Gene3D G3DSA:3.40.50.720 4 250 2.7E-83 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.7E-13 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.7E-13 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.7E-13 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 PANTHER PTHR24322 11 186 1.8E-56 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 3.2E-62 T 16-09-2016 Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 3.0E-6 T 16-09-2016 Spa2297_RS04935 8c7b0f0bf7f5b54b6d6f4628d865e975 253 SUPERFAMILY SSF51735 6 250 3.36E-80 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PANTHER PTHR19375 2 614 0.0 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:2.60.34.10 361 503 2.8E-72 T 16-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 SUPERFAMILY SSF100920 355 511 1.96E-59 T 16-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:1.20.1270.10 504 574 1.0E-26 T 16-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 SUPERFAMILY SSF53067 161 353 1.56E-65 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 610 36.171 T 16-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Pfam PF00012 Hsp70 protein 4 78 7.1E-29 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Pfam PF00012 Hsp70 protein 81 574 1.9E-221 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PANTHER PTHR19375:SF173 2 614 0.0 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 SUPERFAMILY SSF53067 3 159 7.03E-58 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 359 378 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 440 456 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 336 356 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.0E-74 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.90.640.10 200 285 6.6E-31 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.30.420.40 169 199 2.2E-33 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.30.420.40 289 331 2.2E-33 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 7.1E-279 T 16-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.30.420.40 4 38 6.8E-56 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.30.420.40 101 168 6.8E-56 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 Gene3D G3DSA:3.30.30.30 39 100 5.0E-17 T 16-09-2016 Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 SUPERFAMILY SSF100934 478 575 3.73E-14 T 16-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Spa2297_RS17480 62d1b8f8e247314c8f26ce81ad54c4ed 617 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 Gene3D G3DSA:3.10.180.10 162 352 1.1E-58 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 PANTHER PTHR11959 3 353 1.5E-112 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 5 352 6.3E-114 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 Gene3D G3DSA:3.10.180.10 2 145 9.2E-34 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 164 306 1.5E-15 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 PIRSF PIRSF009283 1 354 3.4E-118 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 SUPERFAMILY SSF54593 3 344 1.18E-70 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS26615 ee906b0ed75af7f2bd2ecaccee3efa5d 354 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 47 138 4.6E-11 T 16-09-2016 Spa2297_RS17840 a29031d7093aa685c9683e8edfac2c5c 325 Pfam PF02374 Anion-transporting ATPase 6 180 2.4E-20 T 16-09-2016 IPR025723 Anion-transporting ATPase-like domain Spa2297_RS17840 a29031d7093aa685c9683e8edfac2c5c 325 PANTHER PTHR10803:SF6 1 246 5.8E-137 T 16-09-2016 Spa2297_RS17840 a29031d7093aa685c9683e8edfac2c5c 325 Gene3D G3DSA:3.40.50.300 6 227 6.1E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17840 a29031d7093aa685c9683e8edfac2c5c 325 PANTHER PTHR10803 1 246 5.8E-137 T 16-09-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Spa2297_RS17840 a29031d7093aa685c9683e8edfac2c5c 325 SUPERFAMILY SSF52540 5 225 1.07E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 SMART SM00530 14 69 1.7E-17 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 Gene3D G3DSA:2.60.120.10 88 180 1.0E-13 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 Pfam PF01381 Helix-turn-helix 15 69 4.1E-16 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 Gene3D G3DSA:1.10.260.40 11 87 5.4E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 SUPERFAMILY SSF47413 9 76 1.42E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 Pfam PF07883 Cupin domain 115 178 1.3E-9 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 PANTHER PTHR10245 7 181 1.1E-28 T 16-09-2016 Spa2297_RS02830 1bddd59ba11cd10c765b0940cb3c4d0c 190 SUPERFAMILY SSF51182 67 178 2.39E-17 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS06300 c0cf5db17e58dbc5333428d29134d820 135 Gene3D G3DSA:3.30.450.30 3 127 1.8E-23 T 16-09-2016 Spa2297_RS06300 c0cf5db17e58dbc5333428d29134d820 135 SUPERFAMILY SSF103196 3 129 2.22E-27 T 16-09-2016 Spa2297_RS06300 c0cf5db17e58dbc5333428d29134d820 135 SMART SM00960 9 100 6.8E-26 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS06300 c0cf5db17e58dbc5333428d29134d820 135 Pfam PF03259 Roadblock/LC7 domain 9 99 4.4E-27 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS06300 c0cf5db17e58dbc5333428d29134d820 135 PANTHER PTHR36222 1 133 2.0E-46 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Pfam PF02817 e3 binding domain 167 201 1.6E-13 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Pfam PF00364 Biotin-requiring enzyme 11 81 2.2E-22 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 PANTHER PTHR23151 164 464 1.6E-161 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 PANTHER PTHR23151 1 137 1.6E-161 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Gene3D G3DSA:4.10.320.10 159 207 1.2E-17 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Gene3D G3DSA:2.40.50.100 8 103 7.8E-28 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Gene3D G3DSA:3.30.559.10 224 464 4.0E-82 T 16-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 PANTHER PTHR23151:SF68 164 464 1.6E-161 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 PANTHER PTHR23151:SF68 1 137 1.6E-161 T 16-09-2016 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 236 464 3.6E-77 T 16-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 34 63 - T 16-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 SUPERFAMILY SSF47005 162 206 6.8E-11 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 SUPERFAMILY SSF51230 9 103 5.63E-27 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS16895 3215537e3dc5354ddf8ded577995fe62 467 SUPERFAMILY SSF52777 224 464 1.56E-75 T 16-09-2016 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 SMART SM00342 236 319 6.1E-26 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 PANTHER PTHR11019:SF77 48 327 1.6E-47 T 16-09-2016 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 Pfam PF12833 Helix-turn-helix domain 242 320 2.5E-18 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 Gene3D G3DSA:1.10.10.60 274 326 4.0E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 SUPERFAMILY SSF46689 222 270 1.34E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 PANTHER PTHR11019 48 327 1.6E-47 T 16-09-2016 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 273 315 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 Gene3D G3DSA:2.60.120.10 44 87 7.1E-5 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 303 2.3E-5 T 16-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 319 2.3E-5 T 16-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 Pfam PF12852 Cupin 23 204 1.2E-32 T 16-09-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 SUPERFAMILY SSF46689 272 323 2.78E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29300 41ccfefc96917fdbf67435ad2be58559 334 Gene3D G3DSA:1.10.10.60 222 273 3.6E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11235 9d14bb1d03479d2f432128a9f90f2e35 194 Pfam PF05685 Putative restriction endonuclease 15 184 2.4E-25 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS11235 9d14bb1d03479d2f432128a9f90f2e35 194 PANTHER PTHR35400:SF1 3 194 3.5E-56 T 16-09-2016 Spa2297_RS11235 9d14bb1d03479d2f432128a9f90f2e35 194 PANTHER PTHR35400 3 194 3.5E-56 T 16-09-2016 Spa2297_RS11235 9d14bb1d03479d2f432128a9f90f2e35 194 Gene3D G3DSA:3.90.1570.10 13 164 7.2E-12 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS11235 9d14bb1d03479d2f432128a9f90f2e35 194 SUPERFAMILY SSF52980 28 185 2.14E-17 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 Gene3D G3DSA:3.30.420.40 163 190 3.0E-22 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 Gene3D G3DSA:3.30.420.40 268 322 3.0E-22 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 Gene3D G3DSA:3.30.420.40 15 162 4.3E-20 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 SUPERFAMILY SSF53067 153 332 1.43E-30 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 Gene3D G3DSA:3.90.640.10 191 264 3.0E-11 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PANTHER PTHR19375 13 343 8.4E-89 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 71 94 3.4E-36 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 3.4E-36 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 3.4E-36 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 51 69 3.4E-36 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 3.4E-36 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 SUPERFAMILY SSF53067 14 152 9.61E-21 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 PANTHER PTHR19375:SF176 13 343 8.4E-89 T 16-09-2016 Spa2297_RS10335 5c322def1fe014a2ab1fc576f5288364 349 Pfam PF06723 MreB/Mbl protein 14 336 1.0E-109 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 2.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 2.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 2.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 2.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 Pfam PF12802 MarR family 55 113 1.7E-11 T 16-09-2016 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 SMART SM00347 50 153 5.1E-22 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 ProSitePatterns PS00519 AsnC-type HTH domain signature. 78 104 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 SUPERFAMILY SSF46785 24 167 2.67E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 Gene3D G3DSA:1.10.10.10 19 169 1.9E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PANTHER PTHR33164:SF4 3 175 7.1E-61 T 16-09-2016 Spa2297_RS15585 39afe193d38573dea02c20ba1a32e171 182 PANTHER PTHR33164 3 175 7.1E-61 T 16-09-2016 Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 Pfam PF00082 Subtilase family 213 468 7.5E-56 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 218 229 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PIRSF PIRSF037852 1 1211 0.0 T 16-09-2016 IPR017296 Peptidase S8A, SAM-P45 Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 425 435 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 254 264 - T 16-09-2016 IPR022398 Peptidase S8, subtilisin, His-active site Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PRINTS PR00723 Subtilisin serine protease family (S8) signature 424 440 2.1E-21 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PRINTS PR00723 Subtilisin serine protease family (S8) signature 213 232 2.1E-21 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PRINTS PR00723 Subtilisin serine protease family (S8) signature 250 263 2.1E-21 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PANTHER PTHR10795 183 483 9.0E-78 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 PANTHER PTHR10795:SF419 183 483 9.0E-78 T 16-09-2016 Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 SUPERFAMILY SSF52743 199 482 1.44E-79 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS10330 47f310bd4e9e580e954a7a51f54f1d91 1211 Gene3D G3DSA:3.40.50.200 181 481 2.1E-84 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 PANTHER PTHR10245:SF20 5 284 7.6E-123 T 16-09-2016 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 PANTHER PTHR10245 5 284 7.6E-123 T 16-09-2016 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 SUPERFAMILY SSF47413 10 69 3.84E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 Gene3D G3DSA:1.10.260.40 7 73 3.2E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 SMART SM00530 17 72 6.2E-13 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS14225 c0b60c8c098f6b36fc2ee9db9f4e280a 285 Pfam PF13560 Helix-turn-helix domain 14 69 1.6E-16 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 SUPERFAMILY SSF53335 40 225 3.19E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 PANTHER PTHR10108 213 230 2.8E-65 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 PANTHER PTHR10108:SF889 213 230 2.8E-65 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 PANTHER PTHR10108:SF889 19 159 2.8E-65 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 PANTHER PTHR10108 19 159 2.8E-65 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 Pfam PF13649 Methyltransferase domain 54 146 2.0E-19 T 16-09-2016 Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 Gene3D G3DSA:3.40.50.150 207 242 8.1E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25520 40f76d762382e0c874fb37c95a7efa3f 276 Gene3D G3DSA:3.40.50.150 41 172 8.1E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 SUPERFAMILY SSF48498 94 201 3.71E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.2E-18 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.7E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.7E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 PANTHER PTHR30328 2 208 2.3E-69 T 16-09-2016 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 Gene3D G3DSA:1.10.357.10 65 204 6.3E-30 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 PANTHER PTHR30328:SF24 2 208 2.3E-69 T 16-09-2016 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 SUPERFAMILY SSF46689 11 85 3.8E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS08605 1ce45576c39be2b7495c2d93c7655a79 209 Gene3D G3DSA:1.10.10.60 12 64 2.0E-22 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 Pfam PF00672 HAMP domain 205 272 2.9E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 505 6.7E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 Gene3D G3DSA:1.10.287.130 277 344 2.2E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PANTHER PTHR24423 218 513 2.9E-66 T 16-09-2016 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PANTHER PTHR24423 159 170 2.9E-66 T 16-09-2016 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SMART SM00388 284 357 1.1E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SUPERFAMILY SSF47384 270 357 2.75E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 446 5.7E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 460 5.7E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 503 5.7E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 484 5.7E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SMART SM00387 397 506 1.2E-32 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SUPERFAMILY SSF158472 226 273 3.27E-7 T 16-09-2016 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SMART SM00304 224 276 3.8E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 SUPERFAMILY SSF55874 347 504 1.18E-36 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 357 3.1E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS20765 c6bc28761cdc5b9f221bdc2ae019fb3f 539 Gene3D G3DSA:3.30.565.10 345 505 2.3E-40 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15655 29a110b77428cd94cfc44a9141d8ee50 408 SUPERFAMILY SSF81606 189 395 2.62E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15655 29a110b77428cd94cfc44a9141d8ee50 408 SMART SM00331 171 396 5.5E-26 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15655 29a110b77428cd94cfc44a9141d8ee50 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 396 2.0E-43 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS15655 29a110b77428cd94cfc44a9141d8ee50 408 PANTHER PTHR21021 149 405 1.1E-39 T 16-09-2016 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 338 4.5E-170 T 16-09-2016 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 PANTHER PTHR30011:SF27 14 339 4.2E-110 T 16-09-2016 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 PANTHER PTHR30011 14 339 4.2E-110 T 16-09-2016 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 Pfam PF00296 Luciferase-like monooxygenase 6 313 2.7E-59 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 SUPERFAMILY SSF51679 1 331 1.96E-57 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS26775 7631adfff364417ecb9e1e7cc9992b3a 340 Gene3D G3DSA:3.20.20.30 1 339 9.9E-67 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 PANTHER PTHR37307 2 322 7.9E-127 T 16-09-2016 Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 Pfam PF02650 WhiA C-terminal HTH domain 221 303 2.9E-19 T 16-09-2016 IPR023054 Sporulation regulator WhiA, C-terminal Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 3.2E-23 T 16-09-2016 Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 2.1E-111 T 16-09-2016 Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 6.7E-26 T 16-09-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain Spa2297_RS07860 420aeeeaf3b1e1f755bd66ee9a4b0373 335 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.799 T 16-09-2016 IPR003802 Sporulation regulator WhiA GO:0043937 Spa2297_RS04580 33df51bc568f5c749edee9ffa290a17d 149 SUPERFAMILY SSF52141 3 140 1.83E-34 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04580 33df51bc568f5c749edee9ffa290a17d 149 Gene3D G3DSA:3.40.470.10 2 140 1.4E-42 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04580 33df51bc568f5c749edee9ffa290a17d 149 Pfam PF03167 Uracil DNA glycosylase superfamily 5 134 2.7E-19 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS04580 33df51bc568f5c749edee9ffa290a17d 149 PANTHER PTHR12159 1 140 3.8E-51 T 16-09-2016 IPR015637 G/U mismatch-specific DNA glycosylase GO:0006281|GO:0019104 Spa2297_RS18485 ae691d8fc8e28471aa1f2f08c431467f 263 PANTHER PTHR30294 4 262 1.4E-59 T 16-09-2016 Spa2297_RS18485 ae691d8fc8e28471aa1f2f08c431467f 263 Pfam PF01061 ABC-2 type transporter 28 224 8.9E-36 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS18485 ae691d8fc8e28471aa1f2f08c431467f 263 PANTHER PTHR30294:SF12 4 262 1.4E-59 T 16-09-2016 Spa2297_RS18485 ae691d8fc8e28471aa1f2f08c431467f 263 PIRSF PIRSF006648 1 263 3.9E-21 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 SUPERFAMILY SSF52374 517 782 1.45E-111 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 SUPERFAMILY SSF52374 28 177 1.45E-111 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 SUPERFAMILY SSF52374 227 305 1.45E-111 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:3.90.740.10 303 525 1.1E-49 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 317 342 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:1.10.730.10 763 901 5.5E-35 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 380 557 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 227 286 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 731 965 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 SUPERFAMILY SSF47323 778 964 1.87E-27 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 8 177 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 227 286 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 731 965 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 226 964 2.8E-216 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 8 177 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Pfam PF08264 Anticodon-binding domain of tRNA 814 925 4.8E-13 T 16-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 73 83 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 603 621 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 294 313 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 651 673 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 157 174 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 265 278 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 232 248 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PRINTS PR00985 Leucyl-tRNA synthetase signature 684 694 1.1E-52 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 583 698 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946 380 557 0.0 T 16-09-2016 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 300 505 1.3E-59 T 16-09-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 23 965 21.194 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 583 698 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 PANTHER PTHR11946:SF7 317 342 0.0 T 16-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 SUPERFAMILY SSF50677 305 516 4.19E-42 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:3.40.50.620 526 700 2.9E-133 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:3.40.50.620 226 302 2.9E-133 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:3.40.50.620 733 762 2.9E-133 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Gene3D G3DSA:3.40.50.620 27 176 2.9E-133 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10845 5f69527645c488c430d871e7f1913a5b 966 Pfam PF09334 tRNA synthetases class I (M) 70 172 9.5E-13 T 16-09-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 Gene3D G3DSA:1.10.10.10 6 149 4.4E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 PANTHER PTHR33164 1 160 1.3E-41 T 16-09-2016 Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 Pfam PF01047 MarR family 44 100 8.3E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 PANTHER PTHR33164:SF10 1 160 1.3E-41 T 16-09-2016 Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 SMART SM00347 36 136 2.5E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26015 0468f8c755255705f652879ac8cb9cdc 168 SUPERFAMILY SSF46785 14 149 9.49E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 SUPERFAMILY SSF53067 71 110 6.47E-12 T 16-09-2016 Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 SUPERFAMILY SSF53067 143 321 6.47E-12 T 16-09-2016 Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 368 34.975 T 16-09-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 Pfam PF03702 Uncharacterised protein family (UPF0075) 2 367 8.1E-135 T 16-09-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 Gene3D G3DSA:3.30.420.40 145 328 8.3E-55 T 16-09-2016 Spa2297_RS00870 6eb5cdecc08965fcfcd4b0aba78098d5 393 PANTHER PTHR30605 1 373 1.1E-149 T 16-09-2016 Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 Gene3D G3DSA:3.30.390.10 2 121 1.5E-23 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 Pfam PF13378 Enolase C-terminal domain-like 147 346 1.0E-40 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 33 118 2.0E-6 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 SMART SM00922 137 237 1.5E-16 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 SUPERFAMILY SSF54826 1 118 2.09E-20 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 PANTHER PTHR13794 6 369 1.1E-105 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 SUPERFAMILY SSF51604 117 349 1.23E-47 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 Gene3D G3DSA:3.20.20.120 122 345 1.9E-54 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS32125 f463e379706587e88f0bd4fa47d91b7d 413 PANTHER PTHR13794:SF58 6 369 1.1E-105 T 16-09-2016 Spa2297_RS00865 4ad1acd06c75359d9f9e9e816b5400c4 523 Pfam PF00474 Sodium:solute symporter family 33 435 5.1E-31 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS00865 4ad1acd06c75359d9f9e9e816b5400c4 523 PANTHER PTHR11819 2 497 3.0E-138 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS00865 4ad1acd06c75359d9f9e9e816b5400c4 523 PANTHER PTHR11819:SF94 2 497 3.0E-138 T 16-09-2016 IPR031155 Urea active transporter GO:0015204|GO:0016021|GO:0071918 Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 Pfam PF07690 Major Facilitator Superfamily 8 339 2.7E-36 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 Gene3D G3DSA:1.20.1250.20 202 373 2.4E-8 T 16-09-2016 Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 SUPERFAMILY SSF103473 3 376 9.16E-50 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 PANTHER PTHR23501 1 391 2.6E-132 T 16-09-2016 Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 Gene3D G3DSA:1.20.1250.20 5 186 1.6E-24 T 16-09-2016 Spa2297_RS09400 9de6ef006c8e342406110fc6542ef403 406 PANTHER PTHR23501:SF16 1 391 2.6E-132 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 Gene3D G3DSA:3.50.50.60 278 356 7.6E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 Gene3D G3DSA:3.50.50.60 5 121 7.6E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PANTHER PTHR22912:SF1 173 350 4.5E-18 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PANTHER PTHR22912:SF1 2 156 4.5E-18 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.2E-9 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.2E-9 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 2.2E-9 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PANTHER PTHR22912 173 350 4.5E-18 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 PANTHER PTHR22912 2 156 4.5E-18 T 16-09-2016 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 SUPERFAMILY SSF51905 175 355 6.24E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 Gene3D G3DSA:3.50.50.60 122 277 3.7E-21 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 342 2.3E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15600 7e4b62b3d8ca38efe0d4908e6151f2ed 459 SUPERFAMILY SSF51905 6 223 2.32E-24 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 5.6E-102 T 16-09-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 PANTHER PTHR23105:SF5 19 237 9.9E-80 T 16-09-2016 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 4.8E-52 T 16-09-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 Gene3D G3DSA:3.30.190.20 161 226 1.1E-44 T 16-09-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 Gene3D G3DSA:3.30.190.20 16 68 1.1E-44 T 16-09-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 PIRSF PIRSF002155 1 227 2.4E-72 T 16-09-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 Gene3D G3DSA:3.40.50.790 69 159 1.8E-41 T 16-09-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 SUPERFAMILY SSF56808 8 226 1.44E-82 T 16-09-2016 IPR023674 Ribosomal protein L1-like Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 PANTHER PTHR23105 19 237 9.9E-80 T 16-09-2016 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.977 T 16-09-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19620 d6ef2da3435463de588068685e10607a 241 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 16-09-2016 IPR023673 Ribosomal protein L1, conserved site Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 SUPERFAMILY SSF52540 619 914 3.55E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 SUPERFAMILY SSF52540 435 574 2.66E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 SUPERFAMILY SSF52540 10 205 2.66E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.30.1490.20 131 154 1.9E-24 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.30.1490.20 201 242 1.9E-24 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Pfam PF00005 ABC transporter 628 864 4.7E-11 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 16-09-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 PANTHER PTHR32282 1 966 0.0 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:1.20.1580.10 698 824 5.6E-56 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.801 T 16-09-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 PANTHER PTHR32282:SF2 1 966 0.0 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:1.10.8.280 290 411 1.5E-36 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.40.50.300 616 684 8.4E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.40.50.300 6 90 6.7E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.40.50.300 825 944 8.4E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:3.40.50.300 483 601 6.7E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:1.20.1580.10 412 482 3.7E-56 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:1.20.1580.10 92 130 3.7E-56 T 16-09-2016 Spa2297_RS07900 305dbf59cb3b1df32d4ad8a391c89dfd 1028 Gene3D G3DSA:1.20.1580.10 255 288 3.7E-56 T 16-09-2016 Spa2297_RS03610 59164a0465138d870658861c27081754 115 Pfam PF00085 Thioredoxin 29 109 3.1E-9 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS03610 59164a0465138d870658861c27081754 115 SUPERFAMILY SSF52833 28 111 9.43E-16 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS03610 59164a0465138d870658861c27081754 115 Gene3D G3DSA:3.40.30.10 26 106 1.5E-13 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS04725 8fa4e9f77e3ea0d005539caecebb9056 442 Gene3D G3DSA:3.30.70.260 85 123 4.5E-4 T 16-09-2016 Spa2297_RS04725 8fa4e9f77e3ea0d005539caecebb9056 442 SUPERFAMILY SSF55021 84 124 7.05E-5 T 16-09-2016 Spa2297_RS04725 8fa4e9f77e3ea0d005539caecebb9056 442 SUPERFAMILY SSF55729 262 404 4.96E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04725 8fa4e9f77e3ea0d005539caecebb9056 442 Pfam PF00583 Acetyltransferase (GNAT) family 335 404 7.0E-7 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS04725 8fa4e9f77e3ea0d005539caecebb9056 442 Gene3D G3DSA:3.40.630.30 269 404 1.4E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 SUPERFAMILY SSF52540 445 681 2.28E-36 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 495 619 2.8E-22 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 Gene3D G3DSA:3.40.50.300 446 651 1.7E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 SMART SM00382 490 622 1.4E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 PANTHER PTHR23073 495 688 2.1E-42 T 16-09-2016 Spa2297_RS14960 e0f7ba83dba1593ddb4d9458633cac3c 703 PANTHER PTHR23073:SF24 495 688 2.1E-42 T 16-09-2016 Spa2297_RS10030 f825c76ce10a9c42826a17f20d949732 401 PANTHER PTHR33744 38 401 2.0E-203 T 16-09-2016 Spa2297_RS10030 f825c76ce10a9c42826a17f20d949732 401 Pfam PF13556 PucR C-terminal helix-turn-helix domain 333 390 8.9E-20 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS10030 f825c76ce10a9c42826a17f20d949732 401 PANTHER PTHR33744:SF2 38 401 2.0E-203 T 16-09-2016 Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 SUPERFAMILY SSF52821 4 130 1.13E-34 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 PANTHER PTHR11364:SF10 1 281 5.4E-195 T 16-09-2016 Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 Gene3D G3DSA:3.40.250.10 4 142 9.0E-37 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 Gene3D G3DSA:3.40.250.10 159 277 6.7E-33 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 SUPERFAMILY SSF52821 152 278 6.16E-33 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 SMART SM00450 146 273 4.7E-19 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 SMART SM00450 8 122 3.2E-20 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 Pfam PF00581 Rhodanese-like domain 10 118 2.2E-16 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 Pfam PF00581 Rhodanese-like domain 151 268 4.6E-16 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 PANTHER PTHR11364 1 281 5.4E-195 T 16-09-2016 Spa2297_RS15365 67e85392dac402a55d86ac39ae755fa7 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 16-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 PANTHER PTHR18901:SF14 3 216 1.3E-51 T 16-09-2016 Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 183 1.5E-7 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 79 177 7.0E-7 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 183 6.8E-25 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 PANTHER PTHR18901 3 216 1.3E-51 T 16-09-2016 Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 SUPERFAMILY SSF56784 3 213 3.12E-50 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 Gene3D G3DSA:3.40.50.1000 87 214 1.9E-35 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS29755 ad617d3ef2cd6385ac357e80a504ba17 218 Gene3D G3DSA:3.40.50.1000 3 16 1.9E-35 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS21685 05f03c56841d0b839a15eedc8c254e14 195 SUPERFAMILY SSF48150 14 192 4.5E-65 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS21685 05f03c56841d0b839a15eedc8c254e14 195 Gene3D G3DSA:1.10.340.30 14 192 8.5E-69 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS21685 05f03c56841d0b839a15eedc8c254e14 195 Pfam PF03352 Methyladenine glycosylase 18 190 8.3E-64 T 16-09-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 Spa2297_RS21685 05f03c56841d0b839a15eedc8c254e14 195 PANTHER PTHR30037:SF4 1 195 1.5E-97 T 16-09-2016 Spa2297_RS21685 05f03c56841d0b839a15eedc8c254e14 195 PANTHER PTHR30037 1 195 1.5E-97 T 16-09-2016 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 Gene3D G3DSA:3.40.640.10 8 250 1.0E-102 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 SUPERFAMILY SSF53383 11 383 3.89E-124 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 383 6.1E-150 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 Gene3D G3DSA:3.90.1150.10 254 383 1.2E-49 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 PIRSF PIRSF001434 1 384 3.4E-146 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 PANTHER PTHR11808 1 383 6.3E-299 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS20960 47ed52e9cc11107f16c94bb57a212040 384 PANTHER PTHR11808:SF57 1 383 6.3E-299 T 16-09-2016 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 Gene3D G3DSA:3.90.1150.10 277 418 2.5E-44 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 Gene3D G3DSA:3.40.640.10 90 276 4.7E-20 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 TIGRFAM TIGR01814 kynureninase: kynureninase 21 416 1.6E-75 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 SUPERFAMILY SSF53383 20 418 2.52E-74 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 Pfam PF00266 Aminotransferase class-V 170 320 8.1E-13 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 PANTHER PTHR14084 20 418 2.5E-134 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 PIRSF PIRSF038800 14 419 4.5E-124 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS17605 3ce5243766fb72810ad29b1cbd1b0f52 419 Hamap MF_01970 Kynureninase [kynU]. 11 418 33.842 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 SUPERFAMILY SSF89095 357 499 1.22E-23 T 16-09-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 16-09-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 Gene3D G3DSA:1.10.10.410 442 499 2.8E-5 T 16-09-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 36.519 T 16-09-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 PANTHER PTHR11659:SF0 10 504 1.3E-223 T 16-09-2016 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 SMART SM00845 352 499 5.5E-55 T 16-09-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 499 8.6E-143 T 16-09-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 Pfam PF02934 GatB/GatE catalytic domain 20 314 3.2E-104 T 16-09-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 SUPERFAMILY SSF55931 19 321 8.5E-112 T 16-09-2016 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 PANTHER PTHR11659 10 504 1.3E-223 T 16-09-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 Spa2297_RS23275 ad4bc6342de7bd7032768d987573ff56 504 Pfam PF02637 GatB domain 356 499 9.6E-40 T 16-09-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 38 638 2.8E-196 T 16-09-2016 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969|UniPathway: UPA00223 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Gene3D G3DSA:3.40.50.920 541 642 6.1E-12 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Gene3D G3DSA:3.40.920.10 38 237 2.8E-22 T 16-09-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 SUPERFAMILY SSF53323 40 265 2.75E-16 T 16-09-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 287 501 1.0E-49 T 16-09-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Gene3D G3DSA:3.40.50.970 259 452 5.1E-71 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 SUPERFAMILY SSF52922 542 644 6.85E-16 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154 483 643 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154 281 447 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 544 626 8.0E-9 T 16-09-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154:SF14 483 643 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154:SF14 281 447 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154 27 258 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 SUPERFAMILY SSF52518 262 528 6.8E-59 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 PANTHER PTHR32154:SF14 27 258 3.7E-266 T 16-09-2016 Spa2297_RS19425 ada784ffacacbf2c3f61762a99c25a08 645 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 46 234 6.3E-24 T 16-09-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Spa2297_RS13740 4dcb04793c9c6ed2687ba8fb393c8440 357 PANTHER PTHR34229 2 250 1.9E-93 T 16-09-2016 Spa2297_RS13740 4dcb04793c9c6ed2687ba8fb393c8440 357 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 253 311 7.0E-24 T 16-09-2016 Spa2297_RS13740 4dcb04793c9c6ed2687ba8fb393c8440 357 PANTHER PTHR34229:SF1 2 250 1.9E-93 T 16-09-2016 Spa2297_RS13740 4dcb04793c9c6ed2687ba8fb393c8440 357 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 1.1E-59 T 16-09-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 Spa2297_RS13740 4dcb04793c9c6ed2687ba8fb393c8440 357 Pfam PF13190 PDGLE domain 257 333 2.3E-15 T 16-09-2016 IPR025937 PDGLE domain Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 Pfam PF01175 Urocanase 7 539 6.3E-252 T 16-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 PANTHER PTHR12216 5 550 0.0 T 16-09-2016 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 SUPERFAMILY SSF111326 4 549 1.7E-247 T 16-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 Gene3D G3DSA:3.40.50.10730 137 343 3.7E-84 T 16-09-2016 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 PIRSF PIRSF001423 1 554 9.6E-280 T 16-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 16-09-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 PANTHER PTHR12216:SF3 5 550 0.0 T 16-09-2016 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 2.9E-273 T 16-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 Gene3D G3DSA:3.40.1770.10 6 136 6.2E-151 T 16-09-2016 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 Gene3D G3DSA:3.40.1770.10 354 548 6.2E-151 T 16-09-2016 Spa2297_RS13330 97bd11e14d971d4d4148705c7f970949 557 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 49.033 T 16-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 PANTHER PTHR10196:SF67 1 438 4.3E-117 T 16-09-2016 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 SUPERFAMILY SSF53067 8 248 2.1E-59 T 16-09-2016 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 Gene3D G3DSA:3.30.420.40 250 428 2.8E-16 T 16-09-2016 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 SUPERFAMILY SSF53067 249 462 3.3E-30 T 16-09-2016 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 TIGRFAM TIGR01312 XylB: xylulokinase 10 452 1.1E-142 T 16-09-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 246 6.4E-75 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 341 361 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 PIRSF PIRSF000538 6 477 3.8E-81 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 PANTHER PTHR10196 1 438 4.3E-117 T 16-09-2016 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 312 427 1.4E-13 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS04210 a4980e2ecd011eb419178479ca254cba 481 Gene3D G3DSA:3.30.420.40 5 246 5.1E-60 T 16-09-2016 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 PANTHER PTHR26402 23 200 4.5E-67 T 16-09-2016 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 Gene3D G3DSA:3.40.50.2300 23 143 7.2E-29 T 16-09-2016 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 PANTHER PTHR26402:SF434 23 200 4.5E-67 T 16-09-2016 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 PIRSF PIRSF006171 21 247 1.7E-86 T 16-09-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 Pfam PF00072 Response regulator receiver domain 25 136 3.0E-22 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 SUPERFAMILY SSF52172 24 140 1.99E-31 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS03830 c95b3f4dfdbe4d9e9a7c29b5f36b310b 258 SMART SM00448 23 136 7.7E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 SUPERFAMILY SSF52335 10 199 1.1E-64 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Pfam PF02142 MGS-like domain 22 135 1.4E-23 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Gene3D G3DSA:3.40.140.20 247 364 6.5E-46 T 16-09-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 PIRSF PIRSF000414 4 521 1.1E-196 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 SUPERFAMILY SSF53927 217 521 1.4E-117 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 SMART SM00851 22 136 5.7E-50 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 454 7.8E-115 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Gene3D G3DSA:3.40.140.20 368 511 3.4E-51 T 16-09-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 SMART SM00798 141 455 2.7E-190 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Gene3D G3DSA:3.40.50.1380 9 191 1.1E-76 T 16-09-2016 IPR011607 Methylglyoxal synthase-like domain Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 PANTHER PTHR11692 8 521 1.7E-274 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 PANTHER PTHR11692:SF2 8 521 1.7E-274 T 16-09-2016 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 521 42.329 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS20325 8f1fbd83fb62f0fad1af87c4b6b13b59 521 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 521 1.4E-171 T 16-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 Spa2297_RS26190 ad0d0e04f4a8e43589b0b6db81964699 287 PANTHER PTHR14859 37 286 2.6E-56 T 16-09-2016 IPR027317 PGAP2-interacting protein Spa2297_RS26190 ad0d0e04f4a8e43589b0b6db81964699 287 Gene3D G3DSA:3.60.10.10 37 209 1.5E-13 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS26190 ad0d0e04f4a8e43589b0b6db81964699 287 Gene3D G3DSA:3.60.10.10 210 285 4.0E-6 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS26190 ad0d0e04f4a8e43589b0b6db81964699 287 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 40 275 2.8E-21 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS26190 ad0d0e04f4a8e43589b0b6db81964699 287 SUPERFAMILY SSF56219 31 285 5.5E-35 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 PANTHER PTHR11746:SF63 5 329 1.9E-79 T 16-09-2016 Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 Pfam PF16864 Dimerisation domain 14 88 5.6E-7 T 16-09-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 Gene3D G3DSA:1.10.10.10 8 97 1.1E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 Gene3D G3DSA:3.40.50.150 98 331 1.1E-53 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 SUPERFAMILY SSF46785 10 94 1.79E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 PANTHER PTHR11746 5 329 1.9E-79 T 16-09-2016 Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 PIRSF PIRSF005739 10 334 3.5E-43 T 16-09-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 Pfam PF00891 O-methyltransferase 110 320 2.2E-36 T 16-09-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 Spa2297_RS01510 6a58bce06387c099c24288d2f3b80504 342 SUPERFAMILY SSF53335 94 332 8.6E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 Gene3D G3DSA:3.50.50.60 2 173 5.1E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 Gene3D G3DSA:3.50.50.60 273 351 5.1E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 8.5E-20 T 16-09-2016 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 8.5E-20 T 16-09-2016 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.5E-20 T 16-09-2016 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 8.5E-20 T 16-09-2016 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 SUPERFAMILY SSF51905 4 168 3.09E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 SUPERFAMILY SSF51905 272 363 3.09E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PANTHER PTHR13789 1 370 1.1E-119 T 16-09-2016 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 Pfam PF01494 FAD binding domain 5 338 7.2E-15 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS31965 14bbc76f47c3214cc36e15b7a686527b 372 PANTHER PTHR13789:SF174 1 370 1.1E-119 T 16-09-2016 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 Pfam PF00005 ABC transporter 45 191 7.0E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 PANTHER PTHR24220:SF374 6 16 9.6E-171 T 16-09-2016 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 SUPERFAMILY SSF52540 42 269 1.41E-75 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 PANTHER PTHR24220 40 323 9.6E-171 T 16-09-2016 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 PANTHER PTHR24220 6 16 9.6E-171 T 16-09-2016 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 Gene3D G3DSA:3.40.50.300 38 264 5.1E-77 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 280 1.2E-106 T 16-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 SMART SM00382 52 241 6.1E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 PANTHER PTHR24220:SF374 40 323 9.6E-171 T 16-09-2016 Spa2297_RS06260 9ed59e3a1e8ad5142d2dd42d846d26d0 362 Gene3D G3DSA:3.10.580.10 290 338 1.7E-5 T 16-09-2016 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.2E-9 T 16-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.2E-9 T 16-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.2E-9 T 16-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 PANTHER PTHR33162:SF1 2 144 1.7E-40 T 16-09-2016 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 PANTHER PTHR33162 2 144 1.7E-40 T 16-09-2016 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 Pfam PF02416 mttA/Hcf106 family 5 50 7.6E-6 T 16-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Spa2297_RS21720 ddbcd2047205eeecfd3734c90e6a18f4 150 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 146 14.615 T 16-09-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 Spa2297_RS27070 086a7e7d25bdf2708762c6f2e9b621f2 257 PANTHER PTHR36852 2 251 1.8E-87 T 16-09-2016 Spa2297_RS27070 086a7e7d25bdf2708762c6f2e9b621f2 257 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 1.6E-65 T 16-09-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 Spa2297_RS27070 086a7e7d25bdf2708762c6f2e9b621f2 257 PANTHER PTHR36852:SF1 2 251 1.8E-87 T 16-09-2016 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 Gene3D G3DSA:1.10.1660.10 9 110 3.4E-25 T 16-09-2016 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 SUPERFAMILY SSF46955 9 108 4.76E-23 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 PANTHER PTHR30204:SF18 1 106 1.8E-19 T 16-09-2016 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 5.3E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 5.3E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 5.3E-7 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 PANTHER PTHR30204 1 106 1.8E-19 T 16-09-2016 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 Pfam PF13411 MerR HTH family regulatory protein 9 75 4.4E-16 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31640 e32860408e453da6e5ee371e2de77c19 315 SMART SM00422 8 77 1.5E-22 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 PANTHER PTHR11911 4 122 2.0E-27 T 16-09-2016 Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 SMART SM00116 78 126 3.7E-8 T 16-09-2016 IPR000644 CBS domain Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 SMART SM00116 12 59 0.033 T 16-09-2016 IPR000644 CBS domain Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 Pfam PF00571 CBS domain 5 55 1.4E-6 T 16-09-2016 IPR000644 CBS domain Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 Pfam PF00571 CBS domain 70 123 1.3E-13 T 16-09-2016 IPR000644 CBS domain Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 Gene3D G3DSA:3.10.580.10 4 122 2.9E-31 T 16-09-2016 Spa2297_RS29140 c2311a6f0ebc9f67c397d4b542a7da0b 141 SUPERFAMILY SSF54631 3 121 1.77E-28 T 16-09-2016 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 Pfam PF00202 Aminotransferase class-III 27 430 2.9E-85 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 SUPERFAMILY SSF53383 16 432 5.51E-110 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 PANTHER PTHR11986:SF87 14 437 3.8E-257 T 16-09-2016 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 PANTHER PTHR11986 14 437 3.8E-257 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 Gene3D G3DSA:3.40.640.10 60 312 1.1E-70 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS01110 57b068c2b42f8f009af558f95de3ce53 437 Gene3D G3DSA:3.90.1150.10 313 432 1.5E-31 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS30365 e65d854fd142e5719322bd6262280bf9 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 275 1.1E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30365 e65d854fd142e5719322bd6262280bf9 287 PANTHER PTHR32243:SF28 6 287 1.1E-190 T 16-09-2016 Spa2297_RS30365 e65d854fd142e5719322bd6262280bf9 287 PANTHER PTHR32243 6 287 1.1E-190 T 16-09-2016 Spa2297_RS30365 e65d854fd142e5719322bd6262280bf9 287 Gene3D G3DSA:1.10.3720.10 14 275 2.1E-49 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30365 e65d854fd142e5719322bd6262280bf9 287 SUPERFAMILY SSF161098 11 287 1.07E-52 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 SUPERFAMILY SSF51735 118 278 1.02E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 Pfam PF13602 Zinc-binding dehydrogenase 188 310 2.1E-31 T 16-09-2016 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 SUPERFAMILY SSF50129 3 151 2.28E-39 T 16-09-2016 IPR011032 GroES-like Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 Gene3D G3DSA:3.90.180.10 2 151 2.4E-46 T 16-09-2016 IPR011032 GroES-like Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 SMART SM00829 13 310 2.8E-51 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 16-09-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 PANTHER PTHR11695 18 313 3.7E-104 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 Gene3D G3DSA:3.40.50.720 152 236 6.3E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 PANTHER PTHR11695:SF509 18 313 3.7E-104 T 16-09-2016 Spa2297_RS29805 e2c09e423a2588bb99e0190c5c9d0f24 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 94 1.9E-9 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SUPERFAMILY SSF55785 145 266 8.72E-24 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SMART SM00086 226 268 6.3E-7 T 16-09-2016 IPR001610 PAC motif Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SMART SM00267 268 439 3.8E-62 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Gene3D G3DSA:3.30.450.20 146 266 2.3E-26 T 16-09-2016 Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 PANTHER PTHR33121 389 706 2.3E-79 T 16-09-2016 Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 PANTHER PTHR33121:SF13 389 706 2.3E-79 T 16-09-2016 Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 279 435 4.9E-43 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 277 439 1.2E-33 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SMART SM00091 153 219 8.7E-8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SUPERFAMILY SSF55073 284 441 2.2E-43 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Pfam PF00563 EAL domain 456 698 2.5E-70 T 16-09-2016 IPR001633 EAL domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SUPERFAMILY SSF141868 456 707 3.92E-81 T 16-09-2016 IPR001633 EAL domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 271 9.8E-23 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Pfam PF13426 PAS domain 165 267 1.0E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Gene3D G3DSA:3.20.20.450 453 707 7.9E-95 T 16-09-2016 IPR001633 EAL domain Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 Gene3D G3DSA:3.30.70.270 280 445 1.2E-53 T 16-09-2016 Spa2297_RS29005 98e3a2075e9115fd3a201ac7d87a48ea 714 SMART SM00052 449 703 1.3E-96 T 16-09-2016 IPR001633 EAL domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 PANTHER PTHR24423 280 295 1.2E-15 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 PANTHER PTHR24423 325 448 1.2E-15 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 PANTHER PTHR24423 2 246 1.2E-15 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Gene3D G3DSA:3.30.450.20 124 244 1.0E-23 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Gene3D G3DSA:3.30.450.20 1 100 1.5E-9 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SUPERFAMILY SSF52172 1277 1377 9.53E-12 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SUPERFAMILY SSF55785 119 244 9.95E-20 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SMART SM00448 1281 1397 0.007 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Gene3D G3DSA:3.40.50.2300 1280 1396 2.8E-11 T 16-09-2016 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Pfam PF13426 PAS domain 2 91 0.0026 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Pfam PF00989 PAS fold 133 244 2.9E-13 T 16-09-2016 IPR013767 PAS fold GO:0006355 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SMART SM00091 129 195 2.7E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SMART SM00091 1 58 67.0 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 Pfam PF00072 Response regulator receiver domain 1283 1374 4.2E-5 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 SUPERFAMILY SSF55785 1 87 3.66E-7 T 16-09-2016 IPR000014 PAS domain Spa2297_RS16095 96d8184396301130d91a93c574304616 1407 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 244 5.3E-11 T 16-09-2016 IPR000014 PAS domain Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 PANTHER PTHR30519 8 772 0.0 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 Gene3D G3DSA:3.20.20.210 403 769 2.2E-127 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 SUPERFAMILY SSF51726 12 402 2.49E-100 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 768 34.854 T 16-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 323 5.9E-115 T 16-09-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 SUPERFAMILY SSF51726 406 767 2.75E-112 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 767 0.0 T 16-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 PANTHER PTHR30519:SF0 8 772 0.0 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 Gene3D G3DSA:3.20.20.210 12 399 3.5E-138 T 16-09-2016 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 441 763 3.4E-145 T 16-09-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS28720 fff388dfe55729be8358528efa01883a 772 PIRSF PIRSF000382 9 772 0.0 T 16-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 Gene3D G3DSA:3.40.50.2300 13 139 6.1E-40 T 16-09-2016 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 240 1.5E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 Pfam PF00072 Response regulator receiver domain 22 131 2.0E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 SMART SM00862 167 241 7.0E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 SUPERFAMILY SSF52172 18 198 1.57E-40 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 PANTHER PTHR26402 20 244 8.5E-103 T 16-09-2016 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 SMART SM00448 20 131 1.4E-40 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 Gene3D G3DSA:1.10.10.10 144 243 7.4E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16055 a436b6ae04c374c0f5b8c44c37a140d6 245 PANTHER PTHR26402:SF316 20 244 8.5E-103 T 16-09-2016 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 PANTHER PTHR11649 16 317 2.0E-101 T 16-09-2016 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 Gene3D G3DSA:3.30.300.20 208 313 4.7E-36 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 Pfam PF01926 50S ribosome-binding GTPase 22 134 1.2E-20 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 SUPERFAMILY SSF52540 22 229 2.62E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 Gene3D G3DSA:3.40.50.300 22 207 2.0E-36 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 147 3.2E-16 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 SUPERFAMILY SSF54814 198 317 1.57E-34 T 16-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 Pfam PF07650 KH domain 224 306 1.9E-16 T 16-09-2016 IPR004044 K Homology domain, type 2 GO:0003723 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 TIGRFAM TIGR00436 era: GTP-binding protein Era 19 300 3.7E-66 T 16-09-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 PANTHER PTHR11649:SF3 16 317 2.0E-101 T 16-09-2016 Spa2297_RS10700 9e890ecc99525e6a9e199cf75c6f6409 317 Hamap MF_00367 GTPase Era [era]. 16 317 34.435 T 16-09-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 5.7E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.7E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.7E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 Pfam PF00106 short chain dehydrogenase 16 216 7.3E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 Gene3D G3DSA:3.40.50.720 12 254 1.8E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PANTHER PTHR24320 1 302 2.5E-123 T 16-09-2016 Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.6E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.6E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.6E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.6E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.6E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 SUPERFAMILY SSF51735 10 303 2.32E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10510 2b553eb9f6b66c932bdaa754b31fc2b9 310 PANTHER PTHR24320:SF45 1 302 2.5E-123 T 16-09-2016 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 PANTHER PTHR11986 4 457 1.2E-271 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 Gene3D G3DSA:3.40.640.10 69 342 2.3E-83 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 SUPERFAMILY SSF53383 14 452 4.27E-125 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 Pfam PF00202 Aminotransferase class-III 33 449 5.4E-101 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 255 292 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 PANTHER PTHR11986:SF89 4 457 1.2E-271 T 16-09-2016 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 Gene3D G3DSA:3.90.1150.10 344 452 6.1E-35 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS23885 f310e5c41a4d2cdc5f2fa4286d1732da 457 Gene3D G3DSA:3.90.1150.10 8 67 6.1E-35 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 SUPERFAMILY SSF54909 1 94 2.95E-16 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 1.7E-21 T 16-09-2016 IPR013097 Stress responsive alpha-beta barrel Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 Gene3D G3DSA:3.30.70.900 1 96 8.0E-24 T 16-09-2016 Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 SMART SM00886 2 97 5.3E-21 T 16-09-2016 IPR013097 Stress responsive alpha-beta barrel Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 PANTHER PTHR37832 1 97 1.2E-26 T 16-09-2016 Spa2297_RS15975 0ae38851cf4cac428c76e3ab4b0105ae 97 PANTHER PTHR37832:SF1 1 97 1.2E-26 T 16-09-2016 Spa2297_RS05325 788d6846e477e326092cbddfa7738550 448 PANTHER PTHR23519 3 448 3.0E-92 T 16-09-2016 Spa2297_RS05325 788d6846e477e326092cbddfa7738550 448 Pfam PF11700 Vacuole effluxer Atg22 like 18 440 1.8E-90 T 16-09-2016 IPR024671 Autophagy-related protein 22-like Spa2297_RS05325 788d6846e477e326092cbddfa7738550 448 SUPERFAMILY SSF103473 23 434 1.44E-40 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS05325 788d6846e477e326092cbddfa7738550 448 Gene3D G3DSA:1.20.1250.20 33 221 3.0E-12 T 16-09-2016 Spa2297_RS05325 788d6846e477e326092cbddfa7738550 448 Gene3D G3DSA:1.20.1250.20 251 433 1.7E-19 T 16-09-2016 Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 PANTHER PTHR33164:SF12 32 160 7.7E-59 T 16-09-2016 Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 SMART SM00347 45 146 2.8E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 PANTHER PTHR33164 32 160 7.7E-59 T 16-09-2016 Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 Gene3D G3DSA:1.10.10.10 28 160 2.4E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 SUPERFAMILY SSF46785 27 160 5.07E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29495 95585f7c1f1e455aa0d62e646daabe21 167 Pfam PF12802 MarR family 51 109 1.6E-13 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 PANTHER PTHR10196 1 460 7.4E-118 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 Gene3D G3DSA:3.30.420.40 3 238 3.8E-35 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 PIRSF PIRSF000538 1 478 2.5E-62 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 SUPERFAMILY SSF53067 4 240 6.15E-35 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 246 430 8.6E-19 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 Gene3D G3DSA:3.30.420.40 244 460 4.5E-22 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 238 2.2E-34 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 342 363 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 SUPERFAMILY SSF53067 244 460 2.92E-34 T 16-09-2016 Spa2297_RS10385 08705c921dc9261279ab98cb2aee9b62 484 PANTHER PTHR10196:SF67 1 460 7.4E-118 T 16-09-2016 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 SUPERFAMILY SSF55904 343 489 4.71E-31 T 16-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 Gene3D G3DSA:3.40.640.10 9 285 2.9E-78 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 SUPERFAMILY SSF53383 9 385 2.13E-75 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 Gene3D G3DSA:3.90.1150.10 332 386 1.7E-4 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 420 469 9.0E-14 T 16-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 PANTHER PTHR11751:SF398 9 353 8.7E-75 T 16-09-2016 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 Gene3D G3DSA:3.90.100.10 410 488 1.3E-25 T 16-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 304 5.5E-51 T 16-09-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 Spa2297_RS02125 5457654e4a2364640fadea3a053aab10 492 PANTHER PTHR11751 9 353 8.7E-75 T 16-09-2016 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Gene3D G3DSA:2.140.10.10 318 699 1.0E-35 T 16-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 PANTHER PTHR24362:SF247 19 281 6.8E-92 T 16-09-2016 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SUPERFAMILY SSF50998 362 494 9.42E-8 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00564 456 487 43.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00564 630 661 5.1 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00564 376 407 84.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00564 491 536 580.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00564 589 621 9.9 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SUPERFAMILY SSF56112 19 269 2.56E-65 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Pfam PF00069 Protein kinase domain 22 269 8.2E-38 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Gene3D G3DSA:1.10.510.10 120 300 2.8E-45 T 16-09-2016 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Gene3D G3DSA:3.30.200.20 10 119 3.9E-15 T 16-09-2016 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SMART SM00220 22 276 9.5E-47 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 SUPERFAMILY SSF50998 460 699 2.67E-24 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 PANTHER PTHR24362 19 281 6.8E-92 T 16-09-2016 Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Pfam PF13360 PQQ-like domain 520 698 2.1E-17 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS18460 bc5ec38e99c5c114d444cbfdca929c97 705 Pfam PF13360 PQQ-like domain 356 489 1.9E-14 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 Gene3D G3DSA:1.10.10.10 6 67 5.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 SMART SM00895 76 198 1.8E-20 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 7.3E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 SUPERFAMILY SSF48008 72 199 1.12E-24 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 PANTHER PTHR11751 11 92 5.2E-22 T 16-09-2016 Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 SMART SM00345 8 66 7.2E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 Gene3D G3DSA:1.20.120.530 69 200 1.7E-27 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 Pfam PF07729 FCD domain 76 197 1.6E-24 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS24760 bf1ca6ff8909b4ce3b77db17774224ea 231 SUPERFAMILY SSF46785 7 70 1.68E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 Pfam PF07730 Histidine kinase 302 365 1.1E-12 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 Pfam PF13185 GAF domain 152 284 3.4E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 SMART SM00065 24 129 0.016 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 SMART SM00065 150 294 4.8E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 Gene3D G3DSA:3.30.450.40 9 78 4.8E-6 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 SUPERFAMILY SSF55781 8 144 3.27E-22 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 Gene3D G3DSA:3.30.450.40 141 284 1.7E-17 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 Gene3D G3DSA:3.30.450.40 79 126 1.1E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10340 55b9520066724854474b4fd6ce98667a 481 SUPERFAMILY SSF55781 153 297 8.72E-19 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26780 7f18458513d05c960227dbf93bfe19f7 516 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 42 486 3.7E-154 T 16-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS26780 7f18458513d05c960227dbf93bfe19f7 516 PANTHER PTHR30618 19 506 6.2E-218 T 16-09-2016 Spa2297_RS26780 7f18458513d05c960227dbf93bfe19f7 516 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 37 469 3.2E-147 T 16-09-2016 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 Spa2297_RS26780 7f18458513d05c960227dbf93bfe19f7 516 PANTHER PTHR30618:SF0 19 506 6.2E-218 T 16-09-2016 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-20 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 Gene3D G3DSA:2.10.150.10 121 225 2.4E-36 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 Pfam PF00547 Urease, gamma subunit 2 99 2.5E-34 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 3.8E-30 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 PIRSF PIRSF001225 1 225 1.0E-81 T 16-09-2016 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 124 205 1.6E-27 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 Pfam PF00699 Urease beta subunit 123 202 7.2E-29 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 SUPERFAMILY SSF54111 2 100 2.09E-31 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 Hamap MF_01955 Urease subunit alpha [ureA]. 1 223 41.725 T 16-09-2016 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 Gene3D G3DSA:3.30.280.10 2 99 4.0E-35 T 16-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 PANTHER PTHR33569 2 238 2.6E-97 T 16-09-2016 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 PANTHER PTHR33569:SF1 2 238 2.6E-97 T 16-09-2016 Spa2297_RS23390 96b2ac842082498ce7bf4faf9bc55009 238 SUPERFAMILY SSF51278 109 226 7.72E-37 T 16-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 SUPERFAMILY SSF51161 84 309 2.77E-38 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 Gene3D G3DSA:2.160.10.10 162 316 3.1E-33 T 16-09-2016 Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 Gene3D G3DSA:3.30.60.70 121 161 1.1E-13 T 16-09-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 121 161 2.6E-17 T 16-09-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 11 328 1.4E-152 T 16-09-2016 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117|UniPathway: UPA00034 Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 243 275 1.6E-13 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS07710 eca8d8a61253e51764937656d2c69bc0 329 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 9 326 43.366 T 16-09-2016 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 SUPERFAMILY SSF52172 6 124 4.13E-34 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 SMART SM00448 6 118 1.8E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 PANTHER PTHR26402 6 124 8.0E-44 T 16-09-2016 Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 Pfam PF00072 Response regulator receiver domain 8 118 5.0E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 PANTHER PTHR26402:SF497 6 124 8.0E-44 T 16-09-2016 Spa2297_RS22585 f5c14455a9f80dbf96eee3de56589309 143 Gene3D G3DSA:3.40.50.2300 6 124 6.0E-37 T 16-09-2016 Spa2297_RS31570 9d099b8637752d3407ad3763e9199a11 184 PIRSF PIRSF016897 1 184 1.9E-59 T 16-09-2016 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 Spa2297_RS31570 9d099b8637752d3407ad3763e9199a11 184 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 10 182 1.2E-58 T 16-09-2016 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 Spa2297_RS31570 9d099b8637752d3407ad3763e9199a11 184 Gene3D G3DSA:3.20.20.400 4 184 4.1E-61 T 16-09-2016 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 Spa2297_RS31570 9d099b8637752d3407ad3763e9199a11 184 PANTHER PTHR35787 1 184 2.2E-56 T 16-09-2016 Spa2297_RS31570 9d099b8637752d3407ad3763e9199a11 184 SUPERFAMILY SSF110391 9 184 1.44E-51 T 16-09-2016 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 Gene3D G3DSA:3.40.50.1360 65 211 2.4E-13 T 16-09-2016 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 SUPERFAMILY SSF46785 3 47 4.12E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 PANTHER PTHR30363:SF13 1 289 7.2E-107 T 16-09-2016 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 PANTHER PTHR30363 1 289 7.2E-107 T 16-09-2016 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 Pfam PF08220 DeoR-like helix-turn-helix domain 1 46 3.8E-11 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 44 5.6E-8 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 12 26 5.6E-8 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 SMART SM00420 1 46 2.6E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 Pfam PF00455 DeoR C terminal sensor domain 64 221 4.0E-51 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 SMART SM01134 61 222 4.0E-66 T 16-09-2016 Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 Gene3D G3DSA:1.10.10.10 2 44 5.9E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20830 ef7b75121951dad7d3c830f23de51a07 315 SUPERFAMILY SSF100950 64 223 1.47E-29 T 16-09-2016 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.0E-51 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.0E-51 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.0E-51 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.0E-51 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 16-09-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 362 38.989 T 16-09-2016 IPR000158 Cell division protein FtsZ GO:0005525 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PANTHER PTHR30314 5 400 3.4E-202 T 16-09-2016 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 SUPERFAMILY SSF55307 201 315 5.49E-44 T 16-09-2016 IPR008280 Tubulin/FtsZ, C-terminal Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 Gene3D G3DSA:3.40.50.1440 11 211 3.5E-92 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 PANTHER PTHR30314:SF3 5 400 3.4E-202 T 16-09-2016 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 SMART SM00864 10 202 2.8E-110 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 Gene3D G3DSA:3.30.1330.20 212 315 3.0E-49 T 16-09-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.4E-35 T 16-09-2016 IPR024757 Cell division protein FtsZ, C-terminal Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 SUPERFAMILY SSF52490 9 205 8.77E-68 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 SMART SM00865 204 321 3.9E-57 T 16-09-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 16-09-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 319 5.8E-129 T 16-09-2016 IPR000158 Cell division protein FtsZ GO:0005525 Spa2297_RS08515 afeaab432fa92302afee71294e09f595 400 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 4.0E-38 T 16-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Spa2297_RS06180 97e86d598a46b501d800a0bda5bc67d6 248 Gene3D G3DSA:3.40.1280.10 21 130 5.8E-4 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS06180 97e86d598a46b501d800a0bda5bc67d6 248 Pfam PF07179 SseB protein N-terminal domain 22 141 1.7E-29 T 16-09-2016 IPR009839 SseB protein N-terminal domain Spa2297_RS02515 b678034c1155d931c0e4f85e59ebf036 257 Gene3D G3DSA:3.40.390.10 125 219 3.6E-4 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS02515 b678034c1155d931c0e4f85e59ebf036 257 SUPERFAMILY SSF55486 90 245 1.21E-17 T 16-09-2016 Spa2297_RS02515 b678034c1155d931c0e4f85e59ebf036 257 Pfam PF11350 Protein of unknown function (DUF3152) 67 234 4.7E-39 T 16-09-2016 IPR022603 Domain of unknown function DUF3152 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Gene3D G3DSA:3.40.50.300 76 234 9.1E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 SMART SM00847 466 561 3.3E-37 T 16-09-2016 IPR007502 Helicase-associated domain GO:0004386 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 622 704 8.0E-15 T 16-09-2016 IPR011709 Domain of unknown function DUF1605 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Pfam PF04408 Helicase associated domain (HA2) 468 559 3.0E-18 T 16-09-2016 IPR007502 Helicase-associated domain GO:0004386 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 PANTHER PTHR18934 76 707 0.0 T 16-09-2016 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Pfam PF00271 Helicase conserved C-terminal domain 288 405 2.1E-10 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Pfam PF00270 DEAD/DEAH box helicase 86 234 1.4E-5 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 SMART SM00487 68 260 1.2E-26 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 PANTHER PTHR18934 744 872 0.0 T 16-09-2016 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 SMART SM00490 306 406 2.5E-14 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 PANTHER PTHR18934:SF109 76 707 0.0 T 16-09-2016 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1310 0.0 T 16-09-2016 IPR010222 RNA helicase HrpA GO:0004004 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 PANTHER PTHR18934:SF109 744 872 0.0 T 16-09-2016 Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 SUPERFAMILY SSF52540 74 603 1.1E-112 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Pfam PF11898 Domain of unknown function (DUF3418) 718 1310 4.0E-229 T 16-09-2016 IPR024590 RNA helicase HrpA, C-terminal Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 SMART SM00382 92 386 2.9E-5 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15725 76cbf604710e893e281493b97eb81a80 1314 Gene3D G3DSA:3.40.50.300 277 422 5.1E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 PANTHER PTHR11383 1 314 5.2E-196 T 16-09-2016 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 PANTHER PTHR11383:SF4 1 314 5.2E-196 T 16-09-2016 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 42 137 5.4E-14 T 16-09-2016 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 Pfam PF00293 NUDIX domain 175 282 5.4E-19 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 SUPERFAMILY SSF55811 123 307 1.62E-49 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 Gene3D G3DSA:3.90.79.10 137 306 2.1E-51 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS21900 d00228667b56e9cdfbb48017623b1569 314 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 140 170 7.9E-14 T 16-09-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 Spa2297_RS08430 1bee7c49f2bb531cb67d091e111b3263 446 Gene3D G3DSA:3.90.1200.10 58 240 3.8E-9 T 16-09-2016 Spa2297_RS08430 1bee7c49f2bb531cb67d091e111b3263 446 PANTHER PTHR39441 1 446 2.8E-169 T 16-09-2016 Spa2297_RS08430 1bee7c49f2bb531cb67d091e111b3263 446 SUPERFAMILY SSF56112 72 154 8.67E-9 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS08430 1bee7c49f2bb531cb67d091e111b3263 446 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 30 436 2.1E-119 T 16-09-2016 IPR018721 Protein of unknown function DUF2252 Spa2297_RS13035 b15dd9e334d935a6d606bb9e21029aa2 398 Pfam PF14258 Domain of unknown function (DUF4350) 56 126 2.2E-12 T 16-09-2016 IPR025646 Domain of unknown function DUF4350 Spa2297_RS27770 549050e8274b9198aec6d0a6b0469858 99 SUPERFAMILY SSF54292 16 94 1.36E-19 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS27770 549050e8274b9198aec6d0a6b0469858 99 Gene3D G3DSA:3.10.20.30 16 84 2.7E-5 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS27770 549050e8274b9198aec6d0a6b0469858 99 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 93 3.3E-26 T 16-09-2016 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 7.2E-31 T 16-09-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 22.589 T 16-09-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 SUPERFAMILY SSF141091 1 101 1.31E-29 T 16-09-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.8E-26 T 16-09-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 16-09-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10965 2e538688fa141f1c32d50ee90dbcb2cd 106 PANTHER PTHR21349 1 101 1.1E-31 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 SUPERFAMILY SSF46785 2 109 7.8E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 SUPERFAMILY SSF53850 89 293 1.23E-30 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 Pfam PF03466 LysR substrate binding domain 88 293 2.6E-35 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 PANTHER PTHR30346:SF2 1 310 8.0E-112 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 PANTHER PTHR30346 1 310 8.0E-112 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 Gene3D G3DSA:3.40.190.10 184 265 2.1E-18 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 Gene3D G3DSA:1.10.10.10 7 88 3.0E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 Gene3D G3DSA:3.40.190.10 91 183 1.5E-18 T 16-09-2016 Spa2297_RS01105 b36616247897fb0bea2f252c620cee04 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 6.1E-13 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 Pfam PF00459 Inositol monophosphatase family 11 240 6.1E-53 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PANTHER PTHR20854 4 238 2.0E-71 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PANTHER PTHR20854:SF4 4 238 2.0E-71 T 16-09-2016 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 Gene3D G3DSA:3.40.190.80 165 269 4.6E-29 T 16-09-2016 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 SUPERFAMILY SSF56655 12 268 5.5E-70 T 16-09-2016 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 223 237 - T 16-09-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 16-09-2016 IPR020583 Inositol monophosphatase, metal-binding site Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 Gene3D G3DSA:3.30.540.10 11 164 1.1E-43 T 16-09-2016 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR01959 SuhB family inositol monophosphatase signature 112 131 2.0E-5 T 16-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR01959 SuhB family inositol monophosphatase signature 210 222 2.0E-5 T 16-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 143 166 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 189 210 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS24825 965ba5ff6a7066e898b48424471cd8b1 272 PRINTS PR00377 Inositol monophosphatase superfamily signature 220 244 1.6E-37 T 16-09-2016 IPR000760 Inositol monophosphatase GO:0046854 Spa2297_RS00245 29072823e03978a943ccbdfb87eb9c2d 230 PANTHER PTHR37311:SF1 1 224 2.5E-52 T 16-09-2016 Spa2297_RS00245 29072823e03978a943ccbdfb87eb9c2d 230 Gene3D G3DSA:3.90.1560.10 7 212 7.9E-47 T 16-09-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Spa2297_RS00245 29072823e03978a943ccbdfb87eb9c2d 230 Pfam PF04029 2-phosphosulpholactate phosphatase 13 202 8.8E-31 T 16-09-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Spa2297_RS00245 29072823e03978a943ccbdfb87eb9c2d 230 SUPERFAMILY SSF142823 4 209 2.35E-38 T 16-09-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 Spa2297_RS00245 29072823e03978a943ccbdfb87eb9c2d 230 PANTHER PTHR37311 1 224 2.5E-52 T 16-09-2016 Spa2297_RS11795 2c78cf05394e0a87bf3c3f3bc856cddd 185 PANTHER PTHR31438 10 185 6.7E-59 T 16-09-2016 Spa2297_RS11795 2c78cf05394e0a87bf3c3f3bc856cddd 185 SUPERFAMILY SSF55729 13 177 2.67E-42 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11795 2c78cf05394e0a87bf3c3f3bc856cddd 185 Gene3D G3DSA:3.40.630.30 12 183 6.2E-57 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11795 2c78cf05394e0a87bf3c3f3bc856cddd 185 Pfam PF13523 Acetyltransferase (GNAT) domain 20 163 1.3E-49 T 16-09-2016 Spa2297_RS11795 2c78cf05394e0a87bf3c3f3bc856cddd 185 SMART SM01006 17 64 1.2E-12 T 16-09-2016 IPR019432 Siderophore biosynthesis protein, conserved domain Spa2297_RS08685 a7bee11600f115a500932a11802711b6 450 SUPERFAMILY SSF51569 12 448 8.79E-199 T 16-09-2016 Spa2297_RS08685 a7bee11600f115a500932a11802711b6 450 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 11 450 1.5E-239 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS08685 a7bee11600f115a500932a11802711b6 450 PANTHER PTHR21337 13 450 1.1E-283 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS08685 a7bee11600f115a500932a11802711b6 450 Pfam PF01474 Class-II DAHP synthetase family 13 444 8.1E-202 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS10475 d31d92f5b7cd6a45eb8f9a1d81de5db0 260 Pfam PF01925 Sulfite exporter TauE/SafE 13 252 7.1E-40 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS10475 d31d92f5b7cd6a45eb8f9a1d81de5db0 260 PANTHER PTHR30269 4 260 4.3E-87 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS10475 d31d92f5b7cd6a45eb8f9a1d81de5db0 260 PANTHER PTHR30269:SF0 4 260 4.3E-87 T 16-09-2016 Spa2297_RS19395 34b6e1feee951a590dc0895e55d988eb 483 PANTHER PTHR22979:SF22 117 214 5.8E-21 T 16-09-2016 Spa2297_RS19395 34b6e1feee951a590dc0895e55d988eb 483 PANTHER PTHR22979 117 214 5.8E-21 T 16-09-2016 Spa2297_RS19395 34b6e1feee951a590dc0895e55d988eb 483 PANTHER PTHR22979 235 477 5.8E-21 T 16-09-2016 Spa2297_RS19395 34b6e1feee951a590dc0895e55d988eb 483 PANTHER PTHR22979:SF22 235 477 5.8E-21 T 16-09-2016 Spa2297_RS18020 9ce035e2da0dec30e52b5d4a47d9ee95 306 SUPERFAMILY SSF54909 5 305 7.51E-105 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS18020 9ce035e2da0dec30e52b5d4a47d9ee95 306 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 5 301 1.7E-85 T 16-09-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- Spa2297_RS18020 9ce035e2da0dec30e52b5d4a47d9ee95 306 PANTHER PTHR30521 14 305 1.0E-112 T 16-09-2016 Spa2297_RS18020 9ce035e2da0dec30e52b5d4a47d9ee95 306 PANTHER PTHR30521:SF0 14 305 1.0E-112 T 16-09-2016 Spa2297_RS18020 9ce035e2da0dec30e52b5d4a47d9ee95 306 Pfam PF04261 Dyp-type peroxidase family 5 301 3.5E-95 T 16-09-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 224 2.4E-4 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 Gene3D G3DSA:3.30.360.10 159 374 4.3E-37 T 16-09-2016 Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 PANTHER PTHR22604:SF139 50 381 8.6E-179 T 16-09-2016 Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 Gene3D G3DSA:3.40.50.720 4 158 8.5E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 SUPERFAMILY SSF51735 4 173 1.88E-30 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 134 4.5E-9 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 SUPERFAMILY SSF55347 146 343 4.09E-31 T 16-09-2016 Spa2297_RS11635 33526730cba00b5079eb4e1ff1836d59 383 PANTHER PTHR22604 50 381 8.6E-179 T 16-09-2016 Spa2297_RS31005 425b36d3c0bf857a11209faec08a92b6 195 Gene3D G3DSA:1.25.40.20 22 183 1.0E-23 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS31005 425b36d3c0bf857a11209faec08a92b6 195 PANTHER PTHR24198:SF76 22 185 2.2E-15 T 16-09-2016 Spa2297_RS31005 425b36d3c0bf857a11209faec08a92b6 195 PANTHER PTHR24198 22 185 2.2E-15 T 16-09-2016 Spa2297_RS31005 425b36d3c0bf857a11209faec08a92b6 195 SUPERFAMILY SSF48403 23 180 1.16E-23 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 403 4.5E-116 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 298 9.7E-28 T 16-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Gene3D G3DSA:1.20.5.100 204 233 5.5E-11 T 16-09-2016 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 SUPERFAMILY SSF51735 1 196 4.82E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 405 3.2E-11 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 PANTHER PTHR11374 1 393 7.7E-225 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 PIRSF PIRSF500135 1 438 5.1E-214 T 16-09-2016 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082|UniPathway: UPA00286 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 SUPERFAMILY SSF52413 308 427 2.09E-20 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 SMART SM00984 317 424 1.8E-18 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Gene3D G3DSA:3.40.50.720 235 426 4.5E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 SUPERFAMILY SSF48179 204 298 1.42E-25 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Gene3D G3DSA:3.40.50.720 1 200 1.4E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 PIRSF PIRSF000124 1 438 2.0E-134 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 PANTHER PTHR11374:SF22 1 393 7.7E-225 T 16-09-2016 Spa2297_RS31810 2bfa9395f5dca3be87d44c7166c28654 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 189 1.9E-53 T 16-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 PANTHER PTHR23501:SF4 1 374 1.3E-106 T 16-09-2016 Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 SUPERFAMILY SSF103473 4 374 5.36E-43 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 Pfam PF07690 Major Facilitator Superfamily 8 321 1.2E-27 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 Gene3D G3DSA:1.20.1250.20 5 177 2.3E-21 T 16-09-2016 Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 Gene3D G3DSA:1.20.1250.20 202 374 2.5E-6 T 16-09-2016 Spa2297_RS26845 400a8f674c9fd3c16d5bf531b55f3048 387 PANTHER PTHR23501 1 374 1.3E-106 T 16-09-2016 Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 Pfam PF00535 Glycosyl transferase family 2 6 167 1.5E-32 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 SUPERFAMILY SSF53756 944 1182 2.98E-16 T 16-09-2016 Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 PANTHER PTHR22916 1 473 2.4E-134 T 16-09-2016 Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 SUPERFAMILY SSF53448 3 216 8.16E-53 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 826 1181 2.4E-109 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 Gene3D G3DSA:3.90.550.10 3 221 6.3E-51 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS10945 fcf8d7de515246ed802724a6af98dae5 1187 PANTHER PTHR22916:SF23 1 473 2.4E-134 T 16-09-2016 Spa2297_RS04005 53d42c65c815cbc7d66b243cc819c5fc 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.7 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS04005 53d42c65c815cbc7d66b243cc819c5fc 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 6.2E-24 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS04005 53d42c65c815cbc7d66b243cc819c5fc 124 PANTHER PTHR28259 1 123 5.9E-36 T 16-09-2016 Spa2297_RS04005 53d42c65c815cbc7d66b243cc819c5fc 124 TIGRFAM TIGR00494 crcB: protein CrcB 5 119 8.2E-26 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 Gene3D G3DSA:1.20.1250.20 30 198 9.4E-16 T 16-09-2016 Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 Gene3D G3DSA:1.20.1250.20 219 402 5.5E-8 T 16-09-2016 Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 SUPERFAMILY SSF103473 30 400 6.54E-31 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 Pfam PF07690 Major Facilitator Superfamily 32 326 2.2E-13 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 PANTHER PTHR23530 10 408 2.5E-90 T 16-09-2016 Spa2297_RS05495 f5271046ce59933a66466e67edc4024e 414 PANTHER PTHR23530:SF1 10 408 2.5E-90 T 16-09-2016 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 SUPERFAMILY SSF55785 297 374 2.74E-14 T 16-09-2016 IPR000014 PAS domain Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 SMART SM00091 294 360 6.9E-9 T 16-09-2016 IPR000014 PAS domain Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 SMART SM00065 458 604 0.0012 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 PANTHER PTHR21021:SF19 554 851 3.7E-58 T 16-09-2016 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 Pfam PF13185 GAF domain 458 595 1.3E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 SUPERFAMILY SSF55781 464 605 1.5E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 Gene3D G3DSA:3.30.450.40 456 606 6.0E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 PANTHER PTHR21021 554 851 3.7E-58 T 16-09-2016 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 SMART SM00331 625 843 6.2E-33 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 651 843 7.6E-50 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 Pfam PF08448 PAS fold 301 377 4.5E-12 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS30315 a816dd9076d5d851eeb7e8f9aa3bb7f7 851 Gene3D G3DSA:3.30.450.20 298 395 3.1E-13 T 16-09-2016 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 SUPERFAMILY SSF51905 6 147 1.85E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 SUPERFAMILY SSF51905 235 319 1.85E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 SUPERFAMILY SSF51905 125 240 3.5E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 PANTHER PTHR22912 53 120 5.7E-13 T 16-09-2016 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 PANTHER PTHR22912 137 317 5.7E-13 T 16-09-2016 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 PANTHER PTHR22912:SF1 53 120 5.7E-13 T 16-09-2016 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 PANTHER PTHR22912:SF1 137 317 5.7E-13 T 16-09-2016 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 Gene3D G3DSA:3.50.50.60 5 84 3.8E-20 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 Gene3D G3DSA:3.50.50.60 242 321 3.8E-20 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 Gene3D G3DSA:3.50.50.60 85 241 9.7E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13425 30dea9a5c5a01f340a9b5357a828f3cc 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 308 2.9E-37 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07685 cdf4a0465d2a5011e8ccad965f95dda2 451 Pfam PF01580 FtsK/SpoIIIE family 140 278 1.2E-28 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS07685 cdf4a0465d2a5011e8ccad965f95dda2 451 PANTHER PTHR22683:SF41 7 405 5.7E-136 T 16-09-2016 Spa2297_RS07685 cdf4a0465d2a5011e8ccad965f95dda2 451 SUPERFAMILY SSF52540 153 366 1.59E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07685 cdf4a0465d2a5011e8ccad965f95dda2 451 Gene3D G3DSA:3.40.50.300 164 362 3.8E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07685 cdf4a0465d2a5011e8ccad965f95dda2 451 PANTHER PTHR22683 7 405 5.7E-136 T 16-09-2016 Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 16-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 3.6E-45 T 16-09-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 SUPERFAMILY SSF51230 4 123 2.09E-39 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 Gene3D G3DSA:2.40.50.100 6 123 1.8E-45 T 16-09-2016 Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 Pfam PF01597 Glycine cleavage H-protein 7 122 1.6E-41 T 16-09-2016 IPR002930 Glycine cleavage system H-protein Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 29.47 T 16-09-2016 IPR002930 Glycine cleavage system H-protein Spa2297_RS23130 f915d64219fc155b4d25b22d935b291f 125 PANTHER PTHR11715 1 122 4.9E-58 T 16-09-2016 IPR002930 Glycine cleavage system H-protein Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 PANTHER PTHR22993 1 273 6.0E-145 T 16-09-2016 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 202 3.1E-9 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 Gene3D G3DSA:1.10.8.50 124 260 1.1E-35 T 16-09-2016 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 ProSitePatterns PS01242 Zinc finger FPG-type signature. 231 259 - T 16-09-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 Gene3D G3DSA:3.20.190.10 2 98 1.9E-14 T 16-09-2016 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 SMART SM01232 124 214 1.1E-24 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 93 2.0E-8 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 SUPERFAMILY SSF81624 2 125 2.49E-25 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 PANTHER PTHR22993:SF13 1 273 6.0E-145 T 16-09-2016 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 SUPERFAMILY SSF57716 210 259 4.28E-10 T 16-09-2016 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 SUPERFAMILY SSF46946 123 201 2.62E-19 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS24360 273f028681f111e3f3633526daf5b4cc 289 SMART SM00898 2 110 7.7E-22 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS29860 835410fb0ff04e22894162eb149cbf93 149 Pfam PF04075 Domain of unknown function (DUF385) 14 145 4.9E-53 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS29860 835410fb0ff04e22894162eb149cbf93 149 PANTHER PTHR39428:SF1 1 147 1.2E-59 T 16-09-2016 Spa2297_RS29860 835410fb0ff04e22894162eb149cbf93 149 PANTHER PTHR39428 1 147 1.2E-59 T 16-09-2016 Spa2297_RS29860 835410fb0ff04e22894162eb149cbf93 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 144 2.0E-35 T 16-09-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 SUPERFAMILY SSF51998 630 709 1.46E-132 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 SUPERFAMILY SSF51998 158 595 1.46E-132 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573:SF18 289 898 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573:SF18 37 266 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573 289 898 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 Gene3D G3DSA:3.20.70.20 67 484 3.3E-101 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 Gene3D G3DSA:3.20.70.20 543 589 3.3E-101 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 Gene3D G3DSA:3.20.70.20 656 701 3.3E-101 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573 921 967 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573 37 266 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 7.9E-20 T 16-09-2016 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 96 707 1.2E-188 T 16-09-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 5.3E-148 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PANTHER PTHR11573:SF18 921 967 0.0 T 16-09-2016 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 3.1E-15 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 3.1E-15 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 3.1E-15 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 3.1E-15 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS24580 adf308f96d993124ca9e4c725b7c6e81 967 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 3.1E-15 T 16-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 Gene3D G3DSA:3.40.50.1820 117 363 1.2E-45 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 SUPERFAMILY SSF81296 17 118 2.17E-17 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 PANTHER PTHR10907:SF55 40 318 1.5E-63 T 16-09-2016 Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 Pfam PF00756 Putative esterase 143 359 6.6E-35 T 16-09-2016 IPR000801 Putative esterase Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 SUPERFAMILY SSF53474 129 355 4.73E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 Gene3D G3DSA:2.60.40.10 19 95 3.6E-5 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS31115 15c2ed9a377abd9c18a3839c0f0eab7e 365 PANTHER PTHR10907 40 318 1.5E-63 T 16-09-2016 Spa2297_RS14940 64593c7caa754a599252350d38fb31b4 293 Gene3D G3DSA:3.90.1200.10 113 263 7.4E-5 T 16-09-2016 Spa2297_RS14940 64593c7caa754a599252350d38fb31b4 293 SUPERFAMILY SSF56112 24 276 4.96E-27 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS14940 64593c7caa754a599252350d38fb31b4 293 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 37 276 5.3E-62 T 16-09-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 Spa2297_RS23455 a0a60d2bb8bf542bcc3ba910d1a54fe9 193 PANTHER PTHR11711 18 193 3.0E-59 T 16-09-2016 Spa2297_RS23455 a0a60d2bb8bf542bcc3ba910d1a54fe9 193 SUPERFAMILY SSF52540 16 187 2.07E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23455 a0a60d2bb8bf542bcc3ba910d1a54fe9 193 PANTHER PTHR11711:SF117 18 193 3.0E-59 T 16-09-2016 Spa2297_RS23455 a0a60d2bb8bf542bcc3ba910d1a54fe9 193 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 1.5E-27 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS23455 a0a60d2bb8bf542bcc3ba910d1a54fe9 193 Gene3D G3DSA:3.40.50.300 11 186 1.0E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07010 4ee83bba2c490be1b619d07ccd6b3726 600 Gene3D G3DSA:1.50.10.10 216 593 2.3E-86 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS07010 4ee83bba2c490be1b619d07ccd6b3726 600 Pfam PF00723 Glycosyl hydrolases family 15 220 589 1.5E-76 T 16-09-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 Spa2297_RS07010 4ee83bba2c490be1b619d07ccd6b3726 600 PANTHER PTHR31616 4 592 3.3E-210 T 16-09-2016 Spa2297_RS07010 4ee83bba2c490be1b619d07ccd6b3726 600 PANTHER PTHR31616:SF0 4 592 3.3E-210 T 16-09-2016 Spa2297_RS07010 4ee83bba2c490be1b619d07ccd6b3726 600 SUPERFAMILY SSF48208 192 593 2.65E-113 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS25985 9dcd525b38f63b152dc2a1402cbe62dc 421 Gene3D G3DSA:1.20.1250.20 19 212 5.0E-17 T 16-09-2016 Spa2297_RS25985 9dcd525b38f63b152dc2a1402cbe62dc 421 Pfam PF07690 Major Facilitator Superfamily 32 379 5.3E-27 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS25985 9dcd525b38f63b152dc2a1402cbe62dc 421 PANTHER PTHR23513 8 418 4.4E-67 T 16-09-2016 Spa2297_RS25985 9dcd525b38f63b152dc2a1402cbe62dc 421 Gene3D G3DSA:1.20.1250.20 239 415 3.0E-10 T 16-09-2016 Spa2297_RS25985 9dcd525b38f63b152dc2a1402cbe62dc 421 SUPERFAMILY SSF103473 20 420 5.89E-43 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 108 230 1.9E-46 T 16-09-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 82 239 28.559 T 16-09-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 PANTHER PTHR10884:SF6 38 232 3.4E-95 T 16-09-2016 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 159 214 3.0E-25 T 16-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 SUPERFAMILY SSF143243 96 247 5.36E-47 T 16-09-2016 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 110 231 6.3E-41 T 16-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Spa2297_RS19205 b15303a29983ca6cb1122855f5c719d8 251 PANTHER PTHR10884 38 232 3.4E-95 T 16-09-2016 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 18.189 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 PANTHER PTHR18804 1 37 5.7E-18 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 1.0E-9 T 16-09-2016 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.3E-22 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19915 067be6d6202b24d68dac7f74964d502d 37 SUPERFAMILY SSF57840 1 37 1.57E-17 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 SMART SM00244 80 244 1.0E-10 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 SUPERFAMILY SSF117892 115 246 5.1E-8 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 PANTHER PTHR10264:SF46 272 287 5.8E-73 T 16-09-2016 Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 PANTHER PTHR10264:SF46 61 249 5.8E-73 T 16-09-2016 Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 Pfam PF01145 SPFH domain / Band 7 family 84 253 5.3E-24 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 PANTHER PTHR10264 272 287 5.8E-73 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS21330 8e5a7df00cfca011b48fb6ee723697e4 312 PANTHER PTHR10264 61 249 5.8E-73 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 PANTHER PTHR24220 3 225 2.6E-92 T 16-09-2016 Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 PANTHER PTHR24220:SF86 3 225 2.6E-92 T 16-09-2016 Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 Pfam PF00005 ABC transporter 21 169 1.4E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 Gene3D G3DSA:3.40.50.300 3 222 1.9E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 SUPERFAMILY SSF52540 3 222 6.75E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20905 a8858c41160b48ff1c2cc9cc2377014e 227 SMART SM00382 30 218 2.9E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07485 1502b0e6a08d5a0debb0b83d8b18b777 160 Gene3D G3DSA:3.40.630.30 3 152 3.5E-28 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS07485 1502b0e6a08d5a0debb0b83d8b18b777 160 PANTHER PTHR23091:SF190 1 154 3.6E-50 T 16-09-2016 Spa2297_RS07485 1502b0e6a08d5a0debb0b83d8b18b777 160 SUPERFAMILY SSF55729 4 152 2.57E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS07485 1502b0e6a08d5a0debb0b83d8b18b777 160 PANTHER PTHR23091 1 154 3.6E-50 T 16-09-2016 Spa2297_RS07485 1502b0e6a08d5a0debb0b83d8b18b777 160 Pfam PF13302 Acetyltransferase (GNAT) domain 4 131 2.4E-21 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 PANTHER PTHR24220 223 317 1.0E-94 T 16-09-2016 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 PANTHER PTHR24220 7 191 1.0E-94 T 16-09-2016 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 Gene3D G3DSA:3.40.50.300 6 187 3.3E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 Gene3D G3DSA:3.40.50.300 219 271 3.3E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 PANTHER PTHR24220:SF442 223 317 1.0E-94 T 16-09-2016 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 311 1.3E-10 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 PANTHER PTHR24220:SF442 7 191 1.0E-94 T 16-09-2016 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 SMART SM00382 19 248 7.5E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 Pfam PF00005 ABC transporter 12 167 2.6E-18 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 323 3.3E-15 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 SUPERFAMILY SSF52540 218 259 5.02E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26865 214cf3c1762bcf26397b48cdffd4ac4a 337 SUPERFAMILY SSF52540 9 186 5.02E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 PANTHER PTHR34698 2 210 5.9E-77 T 16-09-2016 Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 Pfam PF02682 Allophanate hydrolase subunit 1 9 200 8.8E-55 T 16-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 SMART SM00796 7 200 7.9E-68 T 16-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 SUPERFAMILY SSF50891 87 211 5.69E-36 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 Gene3D G3DSA:2.40.100.10 87 210 1.3E-44 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS31280 9225103d128f09001974ad02691b1ed2 220 PANTHER PTHR34698:SF2 2 210 5.9E-77 T 16-09-2016 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 112 130 - T 16-09-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 19 338 3.0E-109 T 16-09-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 PIRSF PIRSF006621 16 349 1.5E-98 T 16-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 Pfam PF01207 Dihydrouridine synthase (Dus) 28 330 3.3E-92 T 16-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 PANTHER PTHR11082 10 384 2.3E-177 T 16-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 Gene3D G3DSA:1.10.1200.80 273 342 5.9E-17 T 16-09-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 SUPERFAMILY SSF51395 25 337 4.58E-77 T 16-09-2016 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 Gene3D G3DSA:3.20.20.70 23 264 2.5E-84 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS10535 1b4ec6e005e777ff183530bc2daad290 388 PANTHER PTHR11082:SF25 10 384 2.3E-177 T 16-09-2016 Spa2297_RS04550 a2a588e912cf3510390e026d441971c6 227 SUPERFAMILY SSF53335 24 206 4.45E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04550 a2a588e912cf3510390e026d441971c6 227 Gene3D G3DSA:3.40.50.150 22 193 8.7E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04550 a2a588e912cf3510390e026d441971c6 227 Pfam PF08241 Methyltransferase domain 52 145 2.3E-17 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS04550 a2a588e912cf3510390e026d441971c6 227 PANTHER PTHR10108:SF739 49 192 3.0E-26 T 16-09-2016 Spa2297_RS04550 a2a588e912cf3510390e026d441971c6 227 PANTHER PTHR10108 49 192 3.0E-26 T 16-09-2016 Spa2297_RS28570 27a58a0aa96fbd335668d7f4b89c0b26 225 SUPERFAMILY SSF47616 154 224 2.51E-14 T 16-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like Spa2297_RS28570 27a58a0aa96fbd335668d7f4b89c0b26 225 Pfam PF14497 Glutathione S-transferase, C-terminal domain 155 221 2.8E-6 T 16-09-2016 IPR004046 Glutathione S-transferase, C-terminal Spa2297_RS28570 27a58a0aa96fbd335668d7f4b89c0b26 225 Gene3D G3DSA:1.20.1050.10 156 218 5.1E-11 T 16-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 506 2.9E-209 T 16-09-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 SUPERFAMILY SSF48557 3 503 7.85E-174 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 PANTHER PTHR10362:SF7 3 500 1.8E-211 T 16-09-2016 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 Gene3D G3DSA:1.10.275.10 2 198 2.1E-71 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 16-09-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 Pfam PF00221 Aromatic amino acid lyase 12 472 2.1E-177 T 16-09-2016 IPR001106 Aromatic amino acid lyase Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 PANTHER PTHR10362 3 500 1.8E-211 T 16-09-2016 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 Gene3D G3DSA:1.20.200.10 199 507 1.4E-110 T 16-09-2016 Spa2297_RS20880 f54995ba7c52a6f51dfa50cebd21b608 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 506 43.386 T 16-09-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS31215 4bc8621415f85888f00d7d05fba15848 313 PANTHER PTHR32243 24 312 4.7E-89 T 16-09-2016 Spa2297_RS31215 4bc8621415f85888f00d7d05fba15848 313 SUPERFAMILY SSF161098 75 300 1.7E-47 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31215 4bc8621415f85888f00d7d05fba15848 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 301 8.5E-11 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31215 4bc8621415f85888f00d7d05fba15848 313 PANTHER PTHR32243:SF40 24 312 4.7E-89 T 16-09-2016 Spa2297_RS31215 4bc8621415f85888f00d7d05fba15848 313 Gene3D G3DSA:1.10.3720.10 81 311 1.0E-46 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 SUPERFAMILY SSF55031 211 320 1.15E-19 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 PANTHER PTHR32494:SF5 3 403 6.7E-139 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 PANTHER PTHR32494 3 403 6.7E-139 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 Gene3D G3DSA:3.40.630.10 5 221 1.3E-90 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 Gene3D G3DSA:3.40.630.10 345 403 1.3E-90 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 17 398 1.3E-84 T 16-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 Pfam PF01546 Peptidase family M20/M25/M40 72 400 4.1E-25 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 PIRSF PIRSF001235 2 405 1.1E-123 T 16-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 SUPERFAMILY SSF53187 326 403 6.29E-68 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 SUPERFAMILY SSF53187 14 218 6.29E-68 T 16-09-2016 Spa2297_RS13325 713fc7d15f439f0c82693fc07515cd44 405 Gene3D G3DSA:3.30.70.360 222 322 6.3E-28 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS24060 956ef5be95e84ff0efcdf15e17a3ebde 709 SUPERFAMILY SSF52540 289 629 6.8E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24060 956ef5be95e84ff0efcdf15e17a3ebde 709 Gene3D G3DSA:3.40.50.300 501 652 1.7E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24060 956ef5be95e84ff0efcdf15e17a3ebde 709 Gene3D G3DSA:3.40.50.300 293 379 1.7E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 Pfam PF06445 GyrI-like small molecule binding domain 129 266 2.3E-9 T 16-09-2016 IPR029442 GyrI-like small molecule binding domain Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 Gene3D G3DSA:1.10.1660.10 4 64 9.0E-19 T 16-09-2016 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 PANTHER PTHR30204:SF22 5 276 3.2E-66 T 16-09-2016 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 SMART SM00422 5 75 4.0E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 Pfam PF13411 MerR HTH family regulatory protein 6 73 7.0E-12 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 SMART SM00871 122 273 0.001 T 16-09-2016 IPR010499 Bacterial transcription activator, effector binding Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 Gene3D G3DSA:1.10.1660.10 65 118 3.0E-6 T 16-09-2016 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 Gene3D G3DSA:3.20.80.10 202 268 1.5E-7 T 16-09-2016 IPR011256 Regulatory factor, effector binding domain Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 SUPERFAMILY SSF55136 127 259 1.8E-8 T 16-09-2016 IPR011256 Regulatory factor, effector binding domain Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 PANTHER PTHR30204 5 276 3.2E-66 T 16-09-2016 Spa2297_RS00305 fc8739e5690c3948161fa82ae65dc229 282 SUPERFAMILY SSF46955 5 117 3.44E-22 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 1.5E-5 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 1.5E-5 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.5E-5 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 PANTHER PTHR23501:SF73 3 524 1.8E-195 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 502 5.0E-74 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 Pfam PF07690 Major Facilitator Superfamily 28 422 7.5E-46 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 PANTHER PTHR23501 3 524 1.8E-195 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 Gene3D G3DSA:1.20.1250.20 485 509 2.3E-24 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 Gene3D G3DSA:1.20.1250.20 27 202 6.9E-30 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 Gene3D G3DSA:1.20.1250.20 266 442 2.3E-24 T 16-09-2016 Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 SUPERFAMILY SSF103473 260 432 3.79E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 SUPERFAMILY SSF103473 10 207 3.79E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS30570 6cf9cf08ca199bf44577ae7d1bc40837 541 SUPERFAMILY SSF103473 480 506 3.79E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS28880 7a0a8ddc9c23a6e721cac9404c402e82 160 Gene3D G3DSA:3.40.630.30 2 151 6.9E-30 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28880 7a0a8ddc9c23a6e721cac9404c402e82 160 PANTHER PTHR23091 1 160 1.2E-40 T 16-09-2016 Spa2297_RS28880 7a0a8ddc9c23a6e721cac9404c402e82 160 PANTHER PTHR23091:SF210 1 160 1.2E-40 T 16-09-2016 Spa2297_RS28880 7a0a8ddc9c23a6e721cac9404c402e82 160 Pfam PF00583 Acetyltransferase (GNAT) family 56 134 3.9E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS28880 7a0a8ddc9c23a6e721cac9404c402e82 160 SUPERFAMILY SSF55729 3 159 2.23E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15785 f28754fa113c7edc8500ff6dfdd6e6b0 161 Gene3D G3DSA:1.10.10.10 76 142 5.1E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15785 f28754fa113c7edc8500ff6dfdd6e6b0 161 SUPERFAMILY SSF46785 72 142 2.93E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15785 f28754fa113c7edc8500ff6dfdd6e6b0 161 SMART SM00418 82 155 0.003 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS15785 f28754fa113c7edc8500ff6dfdd6e6b0 161 Pfam PF12840 Helix-turn-helix domain 81 136 7.4E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PANTHER PTHR24423:SF477 43 109 1.8E-77 T 16-09-2016 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 SUPERFAMILY SSF47384 186 263 4.12E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 2.0E-9 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 Gene3D G3DSA:1.10.287.130 193 263 8.8E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 SMART SM00388 202 267 3.5E-9 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 SMART SM00387 309 410 7.0E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 394 2.8E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 Pfam PF00672 HAMP domain 130 197 6.1E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 SUPERFAMILY SSF55874 270 396 1.02E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PANTHER PTHR24423:SF477 143 419 1.8E-77 T 16-09-2016 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 7.6E-8 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 7.6E-8 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 7.6E-8 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PANTHER PTHR24423 143 419 1.8E-77 T 16-09-2016 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 PANTHER PTHR24423 43 109 1.8E-77 T 16-09-2016 Spa2297_RS13270 01dfc2417298c85b57bb645d61d04a61 424 Gene3D G3DSA:3.30.565.10 272 394 7.9E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30475 2de6be19d68f7e482d5babb3c41b61e4 355 PANTHER PTHR30472 12 355 3.0E-102 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS30475 2de6be19d68f7e482d5babb3c41b61e4 355 SUPERFAMILY SSF81345 17 350 6.93E-76 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS30475 2de6be19d68f7e482d5babb3c41b61e4 355 Gene3D G3DSA:1.10.3470.10 18 353 1.0E-102 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS30475 2de6be19d68f7e482d5babb3c41b61e4 355 Pfam PF01032 FecCD transport family 34 350 5.4E-89 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 PANTHER PTHR10196:SF69 1 506 1.1E-267 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 SUPERFAMILY SSF53067 259 502 1.29E-83 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 PIRSF PIRSF000538 2 506 1.4E-160 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 256 1.1E-71 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 455 2.6E-66 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 501 3.6E-222 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 SUPERFAMILY SSF53067 4 259 5.98E-85 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 Gene3D G3DSA:3.30.420.40 259 503 5.1E-102 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 Hamap MF_00186 Glycerol kinase [glpK]. 2 502 54.792 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 Gene3D G3DSA:3.30.420.40 2 257 1.8E-99 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 PANTHER PTHR10196 1 506 1.1E-267 T 16-09-2016 Spa2297_RS31020 ae21ea479b7de92ca68e714ef6253ca0 507 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS31435 ed43c72d7230b353369bface51476aaf 242 Gene3D G3DSA:2.60.120.10 29 97 4.3E-10 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS31435 ed43c72d7230b353369bface51476aaf 242 SUPERFAMILY SSF51182 27 135 3.31E-13 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS31435 ed43c72d7230b353369bface51476aaf 242 Pfam PF07883 Cupin domain 30 90 6.9E-7 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 PANTHER PTHR10937:SF0 1 605 1.4E-294 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 SUPERFAMILY SSF53697 245 605 3.9E-99 T 16-09-2016 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 PANTHER PTHR10937 1 605 1.4E-294 T 16-09-2016 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 9.5E-226 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Pfam PF01380 SIS domain 462 586 1.0E-19 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Pfam PF01380 SIS domain 295 417 2.8E-30 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Pfam PF13522 Glutamine amidotransferase domain 64 193 7.2E-21 T 16-09-2016 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Gene3D G3DSA:3.40.50.10490 245 442 2.3E-69 T 16-09-2016 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Gene3D G3DSA:3.60.20.10 2 240 6.5E-75 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 SUPERFAMILY SSF56235 2 234 1.97E-67 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 37.634 T 16-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 Spa2297_RS11820 2bb9e59ebb361bae5581dd200a356dd7 605 Gene3D G3DSA:3.40.50.10490 443 605 2.0E-57 T 16-09-2016 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 Gene3D G3DSA:3.40.1390.30 115 219 3.0E-31 T 16-09-2016 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 Gene3D G3DSA:3.40.1390.30 3 114 5.6E-41 T 16-09-2016 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 SUPERFAMILY SSF102705 3 272 1.57E-77 T 16-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 250 3.9E-65 T 16-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 268 1.7E-44 T 16-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spa2297_RS09625 fbb6354c7530ab0e8fcbd342f1105324 288 PANTHER PTHR13799 2 274 1.5E-73 T 16-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spa2297_RS28045 25674631e78b74ad4dfb2c667ac33396 490 ProSitePatterns PS00218 Amino acid permeases signature. 63 93 - T 16-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 Spa2297_RS28045 25674631e78b74ad4dfb2c667ac33396 490 PANTHER PTHR11785 4 479 1.1E-280 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28045 25674631e78b74ad4dfb2c667ac33396 490 PIRSF PIRSF006060 25 486 1.4E-56 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28045 25674631e78b74ad4dfb2c667ac33396 490 Pfam PF00324 Amino acid permease 38 479 6.7E-101 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS28045 25674631e78b74ad4dfb2c667ac33396 490 PANTHER PTHR11785:SF25 4 479 1.1E-280 T 16-09-2016 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 PANTHER PTHR19271:SF7 96 473 4.1E-231 T 16-09-2016 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 PANTHER PTHR19271 19 78 4.1E-231 T 16-09-2016 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 PANTHER PTHR19271 96 473 4.1E-231 T 16-09-2016 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 Gene3D G3DSA:1.20.810.10 23 444 3.7E-90 T 16-09-2016 IPR027387 Cytochrome b/b6-like domain Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 PANTHER PTHR19271:SF7 19 78 4.1E-231 T 16-09-2016 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 2.0E-56 T 16-09-2016 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Spa2297_RS08850 b453a31678deeda3f28a0770ea6cde39 545 SUPERFAMILY SSF81342 23 300 3.61E-62 T 16-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 Gene3D G3DSA:3.40.50.720 17 117 2.8E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 SUPERFAMILY SSF52283 2 133 7.18E-31 T 16-09-2016 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 296 1.6E-51 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 PANTHER PTHR10996 1 325 3.5E-138 T 16-09-2016 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 327 1.3E-24 T 16-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 SUPERFAMILY SSF51735 101 297 2.54E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 Gene3D G3DSA:3.40.50.720 118 299 1.1E-55 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 16-09-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spa2297_RS08700 c0b33a9d52242d117e6767134ab52231 331 PANTHER PTHR10996:SF161 1 325 3.5E-138 T 16-09-2016 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 Gene3D G3DSA:1.10.357.10 8 188 1.5E-37 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 PANTHER PTHR30055 5 188 8.0E-33 T 16-09-2016 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 SUPERFAMILY SSF46689 6 84 1.8E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.9E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.7E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.7E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 SUPERFAMILY SSF48498 78 187 3.71E-21 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS03450 1f535a2f86b1f8148ce6cefaf11512e5 192 PANTHER PTHR30055:SF92 5 188 8.0E-33 T 16-09-2016 Spa2297_RS15740 188ed25c7a92e6d4ba082823037fd3ee 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 16-09-2016 Spa2297_RS15740 188ed25c7a92e6d4ba082823037fd3ee 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS15740 188ed25c7a92e6d4ba082823037fd3ee 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 16-09-2016 Spa2297_RS15740 188ed25c7a92e6d4ba082823037fd3ee 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS19370 acf2cc8014a7110d00522a6da9219656 404 SUPERFAMILY SSF89392 139 294 2.79E-17 T 16-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spa2297_RS19370 acf2cc8014a7110d00522a6da9219656 404 Gene3D G3DSA:2.50.20.10 152 294 2.7E-18 T 16-09-2016 Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 SMART SM00382 32 215 3.3E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 Gene3D G3DSA:3.40.50.300 3 229 8.2E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 Pfam PF00005 ABC transporter 24 166 7.5E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 SUPERFAMILY SSF52540 4 228 1.01E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 PANTHER PTHR24220:SF591 5 227 1.8E-106 T 16-09-2016 Spa2297_RS22745 e09c4fdad949e5ee0454da17a7f38f14 260 PANTHER PTHR24220 5 227 1.8E-106 T 16-09-2016 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 Gene3D G3DSA:3.40.50.1400 126 235 5.1E-18 T 16-09-2016 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 Gene3D G3DSA:3.40.50.1400 5 119 5.4E-28 T 16-09-2016 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 Pfam PF01903 CbiX 136 229 4.6E-13 T 16-09-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 Pfam PF01903 CbiX 11 112 6.1E-25 T 16-09-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 PANTHER PTHR33542 6 242 2.7E-64 T 16-09-2016 Spa2297_RS25740 dc674f23428189dc91120848ca0d0472 245 SUPERFAMILY SSF53800 6 235 6.54E-44 T 16-09-2016 Spa2297_RS25660 82af8c3b5e87f989be822fb20a38581f 413 Gene3D G3DSA:1.20.1250.20 25 206 4.0E-23 T 16-09-2016 Spa2297_RS25660 82af8c3b5e87f989be822fb20a38581f 413 Gene3D G3DSA:1.20.1250.20 222 410 4.8E-9 T 16-09-2016 Spa2297_RS25660 82af8c3b5e87f989be822fb20a38581f 413 PANTHER PTHR23517 2 413 2.1E-30 T 16-09-2016 Spa2297_RS25660 82af8c3b5e87f989be822fb20a38581f 413 SUPERFAMILY SSF103473 27 410 3.01E-38 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS25660 82af8c3b5e87f989be822fb20a38581f 413 Pfam PF07690 Major Facilitator Superfamily 30 371 4.9E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS11695 7eefe760b70c18d939a941e8267732b7 273 PANTHER PTHR33607:SF2 42 273 2.6E-93 T 16-09-2016 Spa2297_RS11695 7eefe760b70c18d939a941e8267732b7 273 PANTHER PTHR33607 42 273 2.6E-93 T 16-09-2016 Spa2297_RS11695 7eefe760b70c18d939a941e8267732b7 273 Pfam PF04231 Endonuclease I 58 267 3.0E-40 T 16-09-2016 IPR007346 Endonuclease I GO:0004518 Spa2297_RS11695 7eefe760b70c18d939a941e8267732b7 273 SUPERFAMILY SSF54060 55 267 1.29E-53 T 16-09-2016 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 SMART SM00644 55 186 3.9E-46 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 Gene3D G3DSA:3.40.80.10 47 198 1.0E-44 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 PANTHER PTHR30417 5 199 3.6E-62 T 16-09-2016 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 SUPERFAMILY SSF55846 53 199 7.72E-44 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 PANTHER PTHR30417:SF1 5 199 3.6E-62 T 16-09-2016 Spa2297_RS04220 e18719e7b9a07d00c3450ff9f6add82d 201 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 65 187 1.9E-23 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 PANTHER PTHR34473:SF1 1 424 1.6E-115 T 16-09-2016 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 PANTHER PTHR34473 1 424 1.6E-115 T 16-09-2016 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 PIRSF PIRSF026631 1 418 4.4E-178 T 16-09-2016 IPR014529 Uncharacterised conserved protein UCP026631 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 Pfam PF03703 Bacterial PH domain 329 403 3.1E-15 T 16-09-2016 IPR005182 Domain of unknown function DUF304 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 Pfam PF03703 Bacterial PH domain 229 300 2.7E-7 T 16-09-2016 IPR005182 Domain of unknown function DUF304 Spa2297_RS18230 50f7a680d7b67b490a10651eb33e2d7f 424 Pfam PF03703 Bacterial PH domain 59 136 2.3E-17 T 16-09-2016 IPR005182 Domain of unknown function DUF304 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Gene3D G3DSA:3.30.390.50 224 324 2.3E-33 T 16-09-2016 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 228 323 7.5E-17 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 219 7.9E-48 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 SMART SM01092 226 324 7.8E-29 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 PANTHER PTHR11908 1 119 6.0E-112 T 16-09-2016 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 PANTHER PTHR11908 162 324 6.0E-112 T 16-09-2016 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Gene3D G3DSA:3.30.465.10 56 113 4.9E-35 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Gene3D G3DSA:3.30.465.10 157 219 4.9E-35 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 Gene3D G3DSA:3.30.43.10 3 51 9.6E-11 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 SUPERFAMILY SSF56176 3 219 5.07E-58 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 PANTHER PTHR11908:SF97 1 119 6.0E-112 T 16-09-2016 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 PANTHER PTHR11908:SF97 162 324 6.0E-112 T 16-09-2016 Spa2297_RS29270 b38930e743c353e02e8fb4113ee63b50 338 SUPERFAMILY SSF55447 225 327 3.01E-26 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 356 49.113 T 16-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 16-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 357 50.04 T 16-09-2016 IPR024892 Putative phenylalanine aminotransferase Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 353 4.6E-87 T 16-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 Gene3D G3DSA:3.40.640.10 47 245 6.0E-45 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 SUPERFAMILY SSF53383 26 349 7.84E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 PANTHER PTHR11751:SF347 10 358 1.3E-108 T 16-09-2016 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 Gene3D G3DSA:3.90.1150.10 246 354 2.9E-30 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 PANTHER PTHR11751 10 358 1.3E-108 T 16-09-2016 Spa2297_RS16305 caab1f12797620f3b09d1006fee51989 359 Pfam PF00155 Aminotransferase class I and II 33 346 3.7E-49 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 Gene3D G3DSA:1.10.150.240 25 104 9.9E-6 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 Gene3D G3DSA:3.40.50.1000 105 242 4.1E-32 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 11 213 4.2E-49 T 16-09-2016 IPR010976 Beta-phosphoglucomutase hydrolase Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 PANTHER PTHR18901 1 242 5.7E-106 T 16-09-2016 Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 PANTHER PTHR18901:SF19 1 242 5.7E-106 T 16-09-2016 Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 SUPERFAMILY SSF56784 10 242 8.42E-36 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 216 7.8E-14 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS30090 d600b8dd6faa19d39a8d63e5ba077e37 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 208 3.6E-14 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 SUPERFAMILY SSF52374 2 328 5.63E-77 T 16-09-2016 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 Gene3D G3DSA:1.10.240.10 217 317 6.8E-13 T 16-09-2016 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 Pfam PF00579 tRNA synthetases class I (W and Y) 2 283 4.5E-68 T 16-09-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 2.3E-19 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 2.3E-19 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 207 2.3E-19 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 2.3E-19 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 328 2.1E-90 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PANTHER PTHR10055:SF10 1 332 1.4E-158 T 16-09-2016 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 PANTHER PTHR10055 1 332 1.4E-158 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 Gene3D G3DSA:3.40.50.620 2 216 3.0E-76 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18495 c1c97cb70ea36c8f3241e569d021dfc6 336 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 329 36.051 T 16-09-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Gene3D G3DSA:3.30.43.10 1 51 3.6E-20 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 6.1E-51 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 SMART SM01092 226 324 4.6E-30 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 PANTHER PTHR11908:SF97 1 119 1.8E-153 T 16-09-2016 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 PANTHER PTHR11908:SF97 162 327 1.8E-153 T 16-09-2016 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Gene3D G3DSA:3.30.465.10 157 219 5.9E-32 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Gene3D G3DSA:3.30.465.10 56 113 5.9E-32 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Gene3D G3DSA:3.30.390.50 224 328 7.4E-33 T 16-09-2016 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 323 1.7E-19 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 SUPERFAMILY SSF55447 225 327 8.11E-27 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 PANTHER PTHR11908 1 119 1.8E-153 T 16-09-2016 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 PANTHER PTHR11908 162 327 1.8E-153 T 16-09-2016 Spa2297_RS03815 f44229be30bd2efd73a9c607a5f16ba6 330 SUPERFAMILY SSF56176 1 219 7.48E-58 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 Gene3D G3DSA:1.10.357.10 6 182 5.4E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 PANTHER PTHR30055:SF19 1 181 2.6E-46 T 16-09-2016 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 PANTHER PTHR30055 1 181 2.6E-46 T 16-09-2016 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 SUPERFAMILY SSF48498 84 181 4.89E-10 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.1E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 SUPERFAMILY SSF46689 4 83 4.04E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.9E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS07600 8a58e177a4174257fe845c1202de030a 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.9E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 31.08 T 16-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 PANTHER PTHR10472 2 140 9.7E-62 T 16-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 Gene3D G3DSA:3.50.80.10 1 140 1.3E-53 T 16-09-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 SUPERFAMILY SSF69500 1 140 1.96E-46 T 16-09-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 3.6E-41 T 16-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 Spa2297_RS15270 491020b53c4078e01cf436896d766294 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 2.3E-50 T 16-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 SUPERFAMILY SSF53187 351 438 1.0E-53 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 SUPERFAMILY SSF53187 13 204 1.0E-53 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Gene3D G3DSA:3.40.630.10 13 213 2.4E-60 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Gene3D G3DSA:3.40.630.10 376 439 2.4E-60 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Pfam PF01546 Peptidase family M20/M25/M40 84 439 1.2E-36 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 PANTHER PTHR11014:SF106 12 259 3.4E-116 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 PANTHER PTHR11014:SF106 278 440 3.4E-116 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 PANTHER PTHR11014 12 259 3.4E-116 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 PANTHER PTHR11014 278 440 3.4E-116 T 16-09-2016 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Gene3D G3DSA:3.30.70.360 214 253 1.1E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Gene3D G3DSA:3.30.70.360 291 336 1.1E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 16-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 Pfam PF07687 Peptidase dimerisation domain 201 329 1.9E-15 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 SUPERFAMILY SSF55031 204 249 6.67E-11 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS06530 7ea753244265f17c858b54f3e1fa3650 441 SUPERFAMILY SSF55031 290 330 6.67E-11 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 Pfam PF05139 Erythromycin esterase 52 398 1.5E-72 T 16-09-2016 IPR007815 Erythromycin esterase GO:0046677 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 PIRSF PIRSF036794 1 402 1.0E-87 T 16-09-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 PANTHER PTHR31299 23 325 3.5E-50 T 16-09-2016 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 SUPERFAMILY SSF159501 20 398 7.32E-89 T 16-09-2016 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 Gene3D G3DSA:3.30.1870.10 55 127 5.9E-19 T 16-09-2016 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 PANTHER PTHR31299:SF0 23 325 3.5E-50 T 16-09-2016 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 Gene3D G3DSA:3.40.1660.10 26 53 2.5E-11 T 16-09-2016 Spa2297_RS23185 af612bf63ecb9db519d3490a5012f21c 402 Gene3D G3DSA:3.40.1660.10 278 355 2.5E-11 T 16-09-2016 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 16 303 2.0E-88 T 16-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 PANTHER PTHR11265:SF0 1 306 1.4E-127 T 16-09-2016 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 Gene3D G3DSA:1.10.150.170 107 211 3.9E-35 T 16-09-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 PIRSF PIRSF004486 1 305 9.5E-93 T 16-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 PANTHER PTHR11265 1 306 1.4E-127 T 16-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 SUPERFAMILY SSF53335 1 107 3.95E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 SUPERFAMILY SSF53335 209 304 3.95E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 SUPERFAMILY SSF81799 108 209 3.14E-32 T 16-09-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 1 304 34.291 T 16-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 Gene3D G3DSA:3.40.50.150 212 306 1.3E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 Gene3D G3DSA:3.40.50.150 1 104 1.3E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08565 fdac31a693cbec653c5a9a68a0a77caf 309 Pfam PF01795 MraW methylase family 1 303 2.4E-106 T 16-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 PANTHER PTHR10314 41 427 4.7E-207 T 16-09-2016 Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 Gene3D G3DSA:3.40.50.1100 129 213 1.1E-27 T 16-09-2016 Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 PANTHER PTHR10314:SF96 41 427 4.7E-207 T 16-09-2016 Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 SUPERFAMILY SSF53686 20 413 8.25E-87 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 TIGRFAM TIGR00260 thrC: threonine synthase 74 404 1.4E-80 T 16-09-2016 IPR004450 Threonine synthase-like Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 Gene3D G3DSA:3.40.50.1100 214 409 1.8E-35 T 16-09-2016 Spa2297_RS14820 07701cd742d8014bda9c678876637eaf 430 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 96 399 5.0E-64 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS22195 e1463e809909cae25e09dc29ab724cf1 86 Gene3D G3DSA:3.30.40.10 2 84 6.1E-23 T 16-09-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type Spa2297_RS22195 e1463e809909cae25e09dc29ab724cf1 86 PANTHER PTHR24007 1 83 4.9E-24 T 16-09-2016 Spa2297_RS22195 e1463e809909cae25e09dc29ab724cf1 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 22 82 3.8E-11 T 16-09-2016 IPR001607 Zinc finger, UBP-type GO:0008270 Spa2297_RS22195 e1463e809909cae25e09dc29ab724cf1 86 SUPERFAMILY SSF57850 2 85 4.17E-25 T 16-09-2016 Spa2297_RS04830 71c3565d3380080f088eefab8fd2c487 178 Gene3D G3DSA:2.160.10.10 4 172 1.9E-45 T 16-09-2016 Spa2297_RS04830 71c3565d3380080f088eefab8fd2c487 178 SUPERFAMILY SSF51161 7 169 4.3E-47 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS04830 71c3565d3380080f088eefab8fd2c487 178 PANTHER PTHR13061 3 173 1.9E-72 T 16-09-2016 Spa2297_RS04830 71c3565d3380080f088eefab8fd2c487 178 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 64 90 0.11 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS04830 71c3565d3380080f088eefab8fd2c487 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 93 125 5.8E-7 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS30535 305ce707caa254c732f6f88535875fa2 170 Gene3D G3DSA:3.40.630.30 6 131 3.3E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30535 305ce707caa254c732f6f88535875fa2 170 Pfam PF00583 Acetyltransferase (GNAT) family 57 128 8.2E-8 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS30535 305ce707caa254c732f6f88535875fa2 170 PANTHER PTHR23091:SF235 1 152 1.5E-50 T 16-09-2016 Spa2297_RS30535 305ce707caa254c732f6f88535875fa2 170 SUPERFAMILY SSF55729 8 147 2.06E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30535 305ce707caa254c732f6f88535875fa2 170 PANTHER PTHR23091 1 152 1.5E-50 T 16-09-2016 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 646 736 6.4E-20 T 16-09-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Pfam PF00128 Alpha amylase, catalytic domain 287 356 6.7E-9 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Gene3D G3DSA:2.60.40.1180 641 737 3.2E-27 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 SMART SM00642 268 622 6.6E-8 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 127 735 2.6E-287 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Gene3D G3DSA:2.60.40.10 131 239 7.1E-37 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Gene3D G3DSA:2.60.40.10 36 124 9.6E-17 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 PANTHER PTHR10357 71 597 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 SUPERFAMILY SSF81296 37 132 3.4E-20 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 PIRSF PIRSF000463 29 740 2.4E-292 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 SUPERFAMILY SSF51011 641 737 1.23E-25 T 16-09-2016 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 PANTHER PTHR10357 613 737 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 PANTHER PTHR10357:SF160 613 737 0.0 T 16-09-2016 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 SUPERFAMILY SSF51445 188 635 1.97E-107 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Gene3D G3DSA:3.20.20.80 263 626 3.7E-90 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 143 225 6.8E-21 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 PANTHER PTHR10357:SF160 71 597 0.0 T 16-09-2016 Spa2297_RS02015 21d0eff9e738508cbc5bb93501146744 740 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 119 738 42.615 T 16-09-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 SUPERFAMILY SSF56801 23 538 1.7E-160 T 16-09-2016 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 528 5.3E-18 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Pfam PF00501 AMP-binding enzyme 32 443 2.5E-113 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Gene3D G3DSA:2.30.38.10 359 434 9.8E-28 T 16-09-2016 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Gene3D G3DSA:3.30.300.30 438 538 1.0E-32 T 16-09-2016 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 PANTHER PTHR24095 9 538 9.8E-204 T 16-09-2016 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Gene3D G3DSA:3.40.50.980 29 206 1.1E-41 T 16-09-2016 Spa2297_RS26270 a61ac59f08ab8b1ed2e0a82f205be7c7 545 Gene3D G3DSA:3.40.50.980 207 352 6.4E-51 T 16-09-2016 Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 SUPERFAMILY SSF51735 101 273 7.98E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 Gene3D G3DSA:3.40.50.720 109 275 1.9E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 PANTHER PTHR10996:SF122 4 315 2.7E-190 T 16-09-2016 Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 SUPERFAMILY SSF52283 34 122 9.72E-11 T 16-09-2016 Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 PANTHER PTHR10996 4 315 2.7E-190 T 16-09-2016 Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 274 2.2E-44 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 Gene3D G3DSA:3.40.50.720 27 108 1.1E-9 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12060 8b0a7b331b57391f8428bd5f379a382a 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 305 1.3E-6 T 16-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 Spa2297_RS27180 522e23274cb87f35c36c411f973d7f51 371 PANTHER PTHR15032 95 371 3.7E-106 T 16-09-2016 Spa2297_RS27180 522e23274cb87f35c36c411f973d7f51 371 SUPERFAMILY SSF56281 98 344 3.01E-34 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27180 522e23274cb87f35c36c411f973d7f51 371 Gene3D G3DSA:3.60.15.10 92 353 1.9E-75 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27180 522e23274cb87f35c36c411f973d7f51 371 Pfam PF12706 Beta-lactamase superfamily domain 120 328 3.7E-45 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS27180 522e23274cb87f35c36c411f973d7f51 371 PANTHER PTHR15032:SF4 95 371 3.7E-106 T 16-09-2016 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SUPERFAMILY SSF47413 9 70 1.72E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Gene3D G3DSA:1.25.40.10 86 206 6.4E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SUPERFAMILY SSF48452 275 426 1.01E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Pfam PF13560 Helix-turn-helix domain 9 68 6.4E-11 T 16-09-2016 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00530 13 67 5.2E-10 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Gene3D G3DSA:1.25.40.10 212 427 3.7E-20 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SUPERFAMILY SSF48452 160 317 2.02E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Pfam PF13432 Tetratricopeptide repeat 253 309 0.0046 T 16-09-2016 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Pfam PF13432 Tetratricopeptide repeat 84 151 0.002 T 16-09-2016 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 PANTHER PTHR10245 10 106 1.3E-13 T 16-09-2016 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00028 119 152 30.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00028 282 315 260.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00028 362 395 9.7 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00028 402 435 25.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 SMART SM00028 242 275 87.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS17045 5d45a8ce124862774a8ccbfdc0f2c07a 449 Gene3D G3DSA:1.10.260.40 10 77 1.4E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Gene3D G3DSA:2.40.50.140 287 369 2.0E-29 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SUPERFAMILY SSF50249 280 368 4.72E-26 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Pfam PF00575 S1 RNA binding domain 36 108 4.9E-15 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Pfam PF00575 S1 RNA binding domain 294 366 3.6E-23 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Pfam PF00575 S1 RNA binding domain 209 280 9.6E-26 T 16-09-2016 IPR003029 S1 domain GO:0003676 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SUPERFAMILY SSF50249 32 133 5.3E-22 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SMART SM00316 37 108 1.9E-16 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SMART SM00316 210 280 1.3E-27 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SMART SM00316 124 191 6.5E-11 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SMART SM00316 295 366 1.1E-26 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PANTHER PTHR10724:SF6 22 370 3.7E-120 T 16-09-2016 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PANTHER PTHR10724 22 370 3.7E-120 T 16-09-2016 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Gene3D G3DSA:2.40.50.140 30 109 9.4E-18 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Gene3D G3DSA:2.40.50.140 116 192 8.0E-16 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SUPERFAMILY SSF50249 113 191 1.34E-14 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 SUPERFAMILY SSF50249 210 292 3.29E-27 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 Gene3D G3DSA:2.40.50.140 205 286 1.8E-30 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS08105 97eb98146c457952fa7e749866a92fc7 501 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.1E-86 T 16-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS27250 b94f96699305f973d56b45a5361692a4 246 Gene3D G3DSA:3.40.50.150 4 138 1.7E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27250 b94f96699305f973d56b45a5361692a4 246 Pfam PF08241 Methyltransferase domain 40 134 1.0E-20 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS27250 b94f96699305f973d56b45a5361692a4 246 SUPERFAMILY SSF53335 4 143 1.07E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27250 b94f96699305f973d56b45a5361692a4 246 PANTHER PTHR10108 4 137 8.8E-25 T 16-09-2016 Spa2297_RS22280 f721f3587a50f8e1bc0237dca22a2d2b 69 Gene3D G3DSA:1.10.10.60 37 64 5.1E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22280 f721f3587a50f8e1bc0237dca22a2d2b 69 Pfam PF08279 HTH domain 38 64 4.9E-5 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS22280 f721f3587a50f8e1bc0237dca22a2d2b 69 SUPERFAMILY SSF88659 39 65 8.5E-6 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 PANTHER PTHR21021 89 384 6.5E-47 T 16-09-2016 Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 SUPERFAMILY SSF81606 186 380 7.59E-10 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 SMART SM00331 169 384 5.0E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 384 7.0E-34 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 SUPERFAMILY SSF55781 16 114 2.22E-5 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02595 4c0a64e019ee74913c43e53a8374acef 388 PANTHER PTHR21021:SF22 89 384 6.5E-47 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 SUPERFAMILY SSF53850 55 371 1.35E-89 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 55 368 4.7E-80 T 16-09-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 Pfam PF12849 PBP superfamily domain 51 342 1.0E-59 T 16-09-2016 IPR024370 PBP domain Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 PANTHER PTHR30570:SF0 49 368 2.2E-109 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 PANTHER PTHR30570 49 368 2.2E-109 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 PIRSF PIRSF002756 5 372 8.2E-121 T 16-09-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 Gene3D G3DSA:3.40.190.10 137 312 7.3E-56 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 Gene3D G3DSA:3.40.190.10 315 361 2.8E-7 T 16-09-2016 Spa2297_RS15465 6dbd864d2407f424a75b9ff78acfce11 372 Gene3D G3DSA:3.40.190.10 6 132 2.8E-7 T 16-09-2016 Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 SUPERFAMILY SSF53822 56 329 3.2E-51 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 PANTHER PTHR30036:SF2 7 340 5.3E-129 T 16-09-2016 Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 Gene3D G3DSA:3.40.50.2300 51 175 6.4E-32 T 16-09-2016 Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 Pfam PF13407 Periplasmic binding protein domain 64 303 9.5E-39 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 Gene3D G3DSA:3.40.50.2300 176 308 5.7E-16 T 16-09-2016 Spa2297_RS28480 87b59d8152d10993e3f403a116825bb8 340 PANTHER PTHR30036 7 340 5.3E-129 T 16-09-2016 Spa2297_RS04265 089fa9f78d1e96da03002627c788882e 389 Pfam PF07728 AAA domain (dynein-related subfamily) 100 242 1.9E-36 T 16-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Spa2297_RS04265 089fa9f78d1e96da03002627c788882e 389 SUPERFAMILY SSF52540 80 298 1.49E-17 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04265 089fa9f78d1e96da03002627c788882e 389 Gene3D G3DSA:3.40.50.300 81 256 1.0E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04265 089fa9f78d1e96da03002627c788882e 389 PANTHER PTHR22908 63 381 5.1E-73 T 16-09-2016 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 PANTHER PTHR11921:SF15 7 257 5.5E-121 T 16-09-2016 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 SUPERFAMILY SSF54292 22 126 1.52E-29 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 SUPERFAMILY SSF46548 127 253 3.31E-35 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 Pfam PF13183 4Fe-4S dicluster domain 167 239 5.6E-12 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 PANTHER PTHR11921 7 257 5.5E-121 T 16-09-2016 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 Gene3D G3DSA:1.10.1060.10 127 255 7.0E-40 T 16-09-2016 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 26 131 8.8E-36 T 16-09-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 29 249 7.6E-81 T 16-09-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS20515 908cbd85ee1513522cc3a3dba7526b4e 257 Gene3D G3DSA:3.10.20.30 23 126 1.8E-39 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 PANTHER PTHR26402:SF292 2 225 6.1E-88 T 16-09-2016 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 SMART SM00448 2 113 1.3E-40 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 Pfam PF00072 Response regulator receiver domain 4 114 3.1E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 Gene3D G3DSA:3.40.50.2300 2 120 6.8E-40 T 16-09-2016 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 SUPERFAMILY SSF52172 1 184 9.52E-42 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 PANTHER PTHR26402 2 225 6.1E-88 T 16-09-2016 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 Gene3D G3DSA:1.10.10.10 130 224 4.8E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 3.9E-28 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS13275 f55b2965a4688b666a8380f01efedace 225 SMART SM00862 146 222 1.3E-28 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 PANTHER PTHR33495 1 104 6.3E-23 T 16-09-2016 Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 95 4.1E-20 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 SUPERFAMILY SSF52091 2 97 6.67E-24 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 Pfam PF13466 STAS domain 4 84 3.9E-18 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 PANTHER PTHR33495:SF2 1 104 6.3E-23 T 16-09-2016 Spa2297_RS00175 f0739c8b2acd5ce2c548ed4ee5a65b02 123 Gene3D G3DSA:3.30.750.24 1 98 4.7E-29 T 16-09-2016 IPR002645 STAS domain Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 Pfam PF00672 HAMP domain 181 246 1.1E-12 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 312 5.5E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SUPERFAMILY SSF158472 198 248 1.44E-6 T 16-09-2016 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SUPERFAMILY SSF47384 234 313 1.53E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 Gene3D G3DSA:1.10.287.130 241 309 2.4E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 464 1.3E-18 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 PANTHER PTHR24423 191 464 6.8E-59 T 16-09-2016 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SMART SM00388 251 314 9.8E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SMART SM00304 197 250 4.7E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 Gene3D G3DSA:3.30.565.10 315 468 3.0E-32 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 6.2E-6 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 6.2E-6 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SMART SM00387 356 466 4.0E-26 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24455 4aa4c31b76943eb16f8ee37f90b99dd7 474 SUPERFAMILY SSF55874 303 464 6.42E-31 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 166 2.8E-16 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 241 2.8E-16 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 100 109 2.8E-16 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 2.8E-16 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 SUPERFAMILY SSF55424 307 390 2.06E-16 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 Gene3D G3DSA:3.50.50.60 2 99 4.4E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 SUPERFAMILY SSF51905 1 176 2.0E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 SUPERFAMILY SSF51905 116 299 3.77E-24 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 Pfam PF14759 Reductase C-terminal 311 390 5.6E-12 T 16-09-2016 IPR028202 Reductase, C-terminal Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PANTHER PTHR22912 1 338 6.3E-80 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.9E-22 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 1.9E-22 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 242 1.9E-22 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.9E-22 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 14 1.9E-22 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 Gene3D G3DSA:3.50.50.60 100 235 3.2E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 Gene3D G3DSA:3.30.390.30 311 389 4.8E-18 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 PANTHER PTHR22912:SF180 1 338 6.3E-80 T 16-09-2016 Spa2297_RS05195 030009d32618f3cf16cb6be67f134fca 398 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 289 7.5E-47 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08925 3f6912d343ce98c60be06cec200ec796 473 PANTHER PTHR33119:SF1 1 473 6.5E-108 T 16-09-2016 Spa2297_RS08925 3f6912d343ce98c60be06cec200ec796 473 PANTHER PTHR33119 1 473 6.5E-108 T 16-09-2016 Spa2297_RS08925 3f6912d343ce98c60be06cec200ec796 473 Pfam PF14033 Protein of unknown function (DUF4246) 1 429 3.8E-130 T 16-09-2016 IPR025340 Protein of unknown function DUF4246 Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 Gene3D G3DSA:2.115.10.20 8 295 6.3E-66 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 Pfam PF04616 Glycosyl hydrolases family 43 9 283 1.1E-71 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 Gene3D G3DSA:2.60.120.200 309 503 6.7E-21 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 SUPERFAMILY SSF75005 9 303 1.93E-71 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 PANTHER PTHR22925:SF34 8 489 2.9E-185 T 16-09-2016 Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 PANTHER PTHR22925 8 489 2.9E-185 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS07510 abfe82896dac7c2e07e1fd4f3d559074 509 SUPERFAMILY SSF49899 309 502 1.78E-22 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS24415 0d170c300562538044974a52e8c85718 132 Gene3D G3DSA:3.40.250.10 5 131 4.8E-23 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24415 0d170c300562538044974a52e8c85718 132 SUPERFAMILY SSF52821 11 130 1.09E-23 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24415 0d170c300562538044974a52e8c85718 132 SMART SM00450 21 126 1.5E-19 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24415 0d170c300562538044974a52e8c85718 132 Pfam PF00581 Rhodanese-like domain 23 122 9.2E-10 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS09965 4bea6efa55a0317b05880e3387eb42f6 152 Pfam PF00578 AhpC/TSA family 5 130 3.2E-40 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS09965 4bea6efa55a0317b05880e3387eb42f6 152 Gene3D G3DSA:3.40.30.10 2 152 2.3E-51 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS09965 4bea6efa55a0317b05880e3387eb42f6 152 SUPERFAMILY SSF52833 1 152 2.55E-51 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS09965 4bea6efa55a0317b05880e3387eb42f6 152 PIRSF PIRSF000239 1 152 3.9E-31 T 16-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 Spa2297_RS09965 4bea6efa55a0317b05880e3387eb42f6 152 PANTHER PTHR10681 1 152 7.4E-56 T 16-09-2016 Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 PANTHER PTHR10681 66 191 5.7E-49 T 16-09-2016 Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 Pfam PF00578 AhpC/TSA family 69 188 7.4E-26 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 SUPERFAMILY SSF52833 69 209 7.5E-37 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 PANTHER PTHR10681:SF125 66 191 5.7E-49 T 16-09-2016 Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 Gene3D G3DSA:3.40.30.10 23 209 3.8E-47 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS18795 9a693439dfc6a3b789f2273913bdcad5 211 ProSitePatterns PS00194 Thioredoxin family active site. 94 112 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 Pfam PF04055 Radical SAM superfamily 65 238 5.7E-15 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 50.715 T 16-09-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 2.5E-138 T 16-09-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 PANTHER PTHR22976:SF29 1 384 2.3E-198 T 16-09-2016 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 6.7E-104 T 16-09-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 SUPERFAMILY SSF102114 17 352 1.83E-50 T 16-09-2016 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 PIRSF PIRSF004762 1 373 7.4E-107 T 16-09-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 Gene3D G3DSA:3.20.20.70 18 352 1.1E-62 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS19155 998a10ebe813fc8e32000839704a8191 399 PANTHER PTHR22976 1 384 2.3E-198 T 16-09-2016 Spa2297_RS08265 0c38851679c800955e28891b5872b0e3 387 PANTHER PTHR16222:SF12 13 379 3.2E-79 T 16-09-2016 Spa2297_RS08265 0c38851679c800955e28891b5872b0e3 387 PANTHER PTHR16222 13 379 3.2E-79 T 16-09-2016 Spa2297_RS08265 0c38851679c800955e28891b5872b0e3 387 SUPERFAMILY SSF101478 12 250 1.2E-44 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS08265 0c38851679c800955e28891b5872b0e3 387 SUPERFAMILY SSF101478 281 352 1.2E-44 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS08265 0c38851679c800955e28891b5872b0e3 387 Pfam PF03747 ADP-ribosylglycohydrolase 19 332 3.3E-46 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS29575 11e1fa03426b7bb0e0b9eb043a77ec0a 119 Gene3D G3DSA:2.60.120.10 26 106 1.6E-9 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS29575 11e1fa03426b7bb0e0b9eb043a77ec0a 119 SUPERFAMILY SSF51182 26 107 2.71E-9 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS29575 11e1fa03426b7bb0e0b9eb043a77ec0a 119 Pfam PF05899 Protein of unknown function (DUF861) 61 92 5.9E-8 T 16-09-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 SUPERFAMILY SSF55874 398 532 3.14E-29 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Gene3D G3DSA:3.30.450.20 225 316 1.7E-6 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 SUPERFAMILY SSF55785 226 285 8.38E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 2.6E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 2.6E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 2.6E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Pfam PF17203 Single cache domain 3 47 180 3.5E-24 T 16-09-2016 IPR033463 Single cache domain 3 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Gene3D G3DSA:3.30.565.10 391 535 6.2E-30 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 SUPERFAMILY SSF103190 47 177 1.33E-29 T 16-09-2016 IPR029151 Periplasmic sensor domain-like Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Gene3D G3DSA:3.30.450.20 45 178 3.1E-42 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PANTHER PTHR24423 201 540 8.5E-170 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 532 2.2E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 SUPERFAMILY SSF55890 326 395 8.89E-10 T 16-09-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PANTHER PTHR24423 7 168 8.5E-170 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 SMART SM00387 421 533 2.7E-29 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Gene3D G3DSA:1.10.287.130 317 375 9.0E-19 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PANTHER PTHR24423:SF523 7 168 8.5E-170 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 PANTHER PTHR24423:SF523 201 540 8.5E-170 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 326 373 1.5E-9 T 16-09-2016 Spa2297_RS24705 6ce2d65c523de9b4c65fca54146c4ffe 562 Pfam PF00989 PAS fold 224 263 1.2E-5 T 16-09-2016 IPR013767 PAS fold GO:0006355 Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 SUPERFAMILY SSF51735 9 243 2.67E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.7E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 Gene3D G3DSA:3.40.50.720 3 243 2.0E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25535 845bfb9034a411d033beac424a15c790 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 241 8.6E-26 T 16-09-2016 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 Pfam PF00005 ABC transporter 397 546 1.2E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 Pfam PF00664 ABC transporter transmembrane region 47 314 1.8E-44 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 SUPERFAMILY SSF52540 355 615 7.56E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 PANTHER PTHR24221 392 625 5.4E-205 T 16-09-2016 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 PANTHER PTHR24221 13 372 5.4E-205 T 16-09-2016 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 Gene3D G3DSA:3.40.50.300 361 611 2.1E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 Gene3D G3DSA:1.20.1560.10 30 350 9.1E-74 T 16-09-2016 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 SUPERFAMILY SSF90123 30 348 1.96E-74 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS28650 1f4edf011a603a687c5986c418467f25 626 SMART SM00382 406 592 1.9E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 SMART SM00487 48 257 1.4E-28 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 16 764 0.0 T 16-09-2016 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 PANTHER PTHR24031 36 548 1.8E-129 T 16-09-2016 Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 SUPERFAMILY SSF52540 102 243 9.14E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 SUPERFAMILY SSF52540 280 414 9.14E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 SMART SM00490 317 398 1.1E-18 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 Pfam PF09369 Domain of unknown function (DUF1998) 659 738 3.2E-19 T 16-09-2016 IPR018973 DEAD/DEAH-box helicase, putative Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 Gene3D G3DSA:3.40.50.300 281 437 1.1E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 PANTHER PTHR24031:SF122 36 548 1.8E-129 T 16-09-2016 Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 Pfam PF00270 DEAD/DEAH box helicase 54 229 6.6E-25 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 Gene3D G3DSA:3.40.50.300 36 231 7.4E-35 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17960 030e1e485ae51402731bbff5c6e1402f 785 Pfam PF00271 Helicase conserved C-terminal domain 288 398 1.2E-12 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 SUPERFAMILY SSF48317 22 164 2.09E-30 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 PANTHER PTHR14969 1 158 1.5E-64 T 16-09-2016 Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 PANTHER PTHR14969:SF24 1 158 1.5E-64 T 16-09-2016 Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 SMART SM00014 60 160 4.8E-7 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 Gene3D G3DSA:1.20.144.10 4 158 1.1E-25 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS20445 fff5aa2e8ff8d0b5d1e3d3de0eb79a71 169 Pfam PF01569 PAP2 superfamily 63 160 1.8E-15 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 PANTHER PTHR10093 109 140 2.7E-41 T 16-09-2016 Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 PANTHER PTHR10093 3 90 2.7E-41 T 16-09-2016 Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 Gene3D G3DSA:3.90.1010.10 5 148 7.0E-45 T 16-09-2016 Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 SUPERFAMILY SSF82649 2 142 1.1E-43 T 16-09-2016 Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 1.1E-47 T 16-09-2016 Spa2297_RS07730 8a81a444b7b1456d075b27e64ac7e1dc 156 Pfam PF01592 NifU-like N terminal domain 6 129 4.4E-26 T 16-09-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 199 3.5E-71 T 16-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 199 2.8E-60 T 16-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 Gene3D G3DSA:3.40.50.300 10 199 1.9E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 PIRSF PIRSF015617 3 199 1.6E-65 T 16-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 SUPERFAMILY SSF52540 12 199 5.05E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07395 05b1e3a6fbed13284d1d9ba2117d7133 199 PANTHER PTHR30069 7 199 2.4E-53 T 16-09-2016 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 PANTHER PTHR11271 33 444 4.2E-78 T 16-09-2016 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 Pfam PF01979 Amidohydrolase family 67 416 7.2E-44 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 Gene3D G3DSA:2.30.40.10 21 76 8.9E-10 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 Gene3D G3DSA:3.20.20.140 77 386 7.6E-66 T 16-09-2016 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 SUPERFAMILY SSF51338 25 83 3.7E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 PANTHER PTHR11271:SF7 33 444 4.2E-78 T 16-09-2016 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 SUPERFAMILY SSF51338 349 445 4.86E-18 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31580 b2824653a12ed9f462f6a2d03ad50b15 468 SUPERFAMILY SSF51556 69 368 1.45E-66 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS07225 1f5a6285df8db05ce2e92df69519aaff 507 PANTHER PTHR30624 6 503 2.4E-228 T 16-09-2016 Spa2297_RS07225 1f5a6285df8db05ce2e92df69519aaff 507 PANTHER PTHR30624:SF10 6 503 2.4E-228 T 16-09-2016 Spa2297_RS07225 1f5a6285df8db05ce2e92df69519aaff 507 SUPERFAMILY SSF111283 13 498 3.66E-97 T 16-09-2016 Spa2297_RS07225 1f5a6285df8db05ce2e92df69519aaff 507 Pfam PF01523 Putative modulator of DNA gyrase 32 347 3.0E-48 T 16-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS22170 c15524a909adfa07c07c81cd9231cc5d 85 PANTHER PTHR38839:SF3 1 81 2.3E-39 T 16-09-2016 Spa2297_RS22170 c15524a909adfa07c07c81cd9231cc5d 85 Pfam PF02467 Transcription factor WhiB 3 71 1.0E-27 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS22170 c15524a909adfa07c07c81cd9231cc5d 85 PANTHER PTHR38839 1 81 2.3E-39 T 16-09-2016 Spa2297_RS22170 c15524a909adfa07c07c81cd9231cc5d 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 82 14.331 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 Pfam PF15632 ATP-grasp in the biosynthetic pathway with Ter operon 6 333 2.1E-101 T 16-09-2016 IPR011226 ATP-grasp family Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 Gene3D G3DSA:3.40.50.20 21 123 2.0E-13 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 PIRSF PIRSF029120 1 364 8.6E-160 T 16-09-2016 IPR011226 ATP-grasp family Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 Gene3D G3DSA:3.30.470.20 219 319 2.7E-10 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 SUPERFAMILY SSF56059 96 326 2.36E-28 T 16-09-2016 Spa2297_RS27730 d75032d05b35ed3ebd79e09c90a02216 373 Gene3D G3DSA:3.30.1490.20 127 174 3.7E-6 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 19 183 3.4E-29 T 16-09-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 SUPERFAMILY SSF46785 98 171 2.16E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 Gene3D G3DSA:1.10.10.10 98 171 4.4E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 PANTHER PTHR34298 10 217 3.2E-66 T 16-09-2016 Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 Gene3D G3DSA:1.10.10.10 19 94 1.0E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 SUPERFAMILY SSF46785 17 93 2.27E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 Pfam PF04079 Segregation and condensation complex subunit ScpB 23 180 2.4E-55 T 16-09-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 PIRSF PIRSF019345 5 216 2.6E-53 T 16-09-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spa2297_RS06970 71703eda05597b2834b09d826097e17e 217 PANTHER PTHR34298:SF2 10 217 3.2E-66 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 839 3.2E-190 T 16-09-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF56037 208 414 1.6E-63 T 16-09-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Pfam PF03147 Ferredoxin-fold anticodon binding domain 745 839 5.7E-21 T 16-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.30.56.10 164 193 8.0E-19 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.30.56.10 1 40 8.0E-19 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF54991 741 839 1.44E-22 T 16-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 PANTHER PTHR10947:SF0 2 600 3.1E-285 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 PANTHER PTHR10947:SF0 622 839 3.1E-285 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.30.56.20 419 490 4.0E-22 T 16-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF55681 482 598 2.68E-43 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF55681 628 732 2.68E-43 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:2.40.50.140 45 162 2.1E-38 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.30.930.10 502 732 2.2E-65 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF46955 420 490 5.58E-15 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 833 39.859 T 16-09-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.30.70.380 747 839 6.7E-26 T 16-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SMART SM00873 221 403 5.2E-81 T 16-09-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SUPERFAMILY SSF50249 45 205 2.74E-33 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Pfam PF01588 Putative tRNA binding domain 48 154 1.7E-20 T 16-09-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SMART SM00874 419 486 2.7E-21 T 16-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Gene3D G3DSA:3.50.40.10 210 413 8.9E-82 T 16-09-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Pfam PF03483 B3/4 domain 221 403 2.8E-67 T 16-09-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 Pfam PF03484 tRNA synthetase B5 domain 421 486 2.6E-17 T 16-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 PANTHER PTHR10947 2 600 3.1E-285 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 PANTHER PTHR10947 622 839 3.1E-285 T 16-09-2016 Spa2297_RS06140 87520b7e1b82fc528449e33177c6b06e 840 SMART SM00896 745 839 1.5E-37 T 16-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 SUPERFAMILY SSF51905 7 236 4.98E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 SUPERFAMILY SSF51905 273 334 4.98E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 359 369 - T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 Gene3D G3DSA:3.50.50.60 3 235 1.0E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PANTHER PTHR11985 1 535 1.9E-224 T 16-09-2016 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 324 330 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 6 18 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 35 47 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 81 93 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 19 29 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 354 366 3.5E-30 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 387 511 7.0E-31 T 16-09-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 Pfam PF01266 FAD dependent oxidoreductase 7 360 4.7E-50 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS20135 45b52e0907a535f2c3034c19871fb0c5 551 PANTHER PTHR11985:SF1 1 535 1.9E-224 T 16-09-2016 Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 Pfam PF13622 Thioesterase-like superfamily 33 284 9.0E-62 T 16-09-2016 Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 SUPERFAMILY SSF54637 117 286 9.95E-49 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 Gene3D G3DSA:3.10.129.10 4 114 4.8E-49 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 Gene3D G3DSA:3.10.129.10 126 286 3.4E-53 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 PANTHER PTHR11066 8 288 3.6E-113 T 16-09-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Spa2297_RS04125 f2167eedddb50bec320a877b7d72b6fa 288 SUPERFAMILY SSF54637 5 114 5.83E-42 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS16840 cb198ff8089eed13839d2522fe7d9717 282 PANTHER PTHR30294 35 282 1.4E-107 T 16-09-2016 Spa2297_RS16840 cb198ff8089eed13839d2522fe7d9717 282 PANTHER PTHR30294:SF24 35 282 1.4E-107 T 16-09-2016 Spa2297_RS16840 cb198ff8089eed13839d2522fe7d9717 282 PIRSF PIRSF006648 2 282 7.0E-75 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS16840 cb198ff8089eed13839d2522fe7d9717 282 Pfam PF01061 ABC-2 type transporter 43 248 3.9E-34 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS18600 03ee667ad3d8edd0c0494adc13de55c5 135 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 133 7.0E-9 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS18600 03ee667ad3d8edd0c0494adc13de55c5 135 Gene3D G3DSA:3.30.530.20 7 134 1.1E-54 T 16-09-2016 IPR023393 START-like domain Spa2297_RS18600 03ee667ad3d8edd0c0494adc13de55c5 135 SUPERFAMILY SSF55961 8 134 1.39E-33 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 2625 2796 3.11E-37 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.30.300.30 2034 2126 2.1E-24 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 735 889 5.11E-23 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF56801 106 662 4.06E-145 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095:SF173 316 800 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 292 443 2.1E-41 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 1786 1939 2.4E-42 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF47336 644 712 3.01E-15 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 3239 3358 1.2E-26 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095 1168 2204 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095 2583 3540 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095 316 800 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:1.10.1200.10 3571 3638 2.8E-17 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:1.10.1200.10 2139 2216 2.9E-14 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:1.10.1200.10 655 717 8.5E-21 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 2235 2407 3.22E-20 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00501 AMP-binding enzyme 3062 3458 7.1E-84 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00501 AMP-binding enzyme 146 542 1.3E-96 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00501 AMP-binding enzyme 1624 2039 1.8E-93 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 1367 1605 2.22E-44 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1776 1787 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF13193 AMP-binding enzyme C-terminal domain 2048 2115 1.3E-8 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF13193 AMP-binding enzyme C-terminal domain 3466 3540 9.1E-12 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF13193 AMP-binding enzyme C-terminal domain 551 626 1.3E-13 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2173 2188 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095:SF173 1168 2204 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 PANTHER PTHR24095:SF173 2583 3540 0.0 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 140 291 4.6E-40 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 1617 1785 9.5E-42 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.40.50.980 3053 3221 4.5E-39 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 2801 3028 5.28E-48 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 1191 1381 1.78E-37 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SMART SM00823 Phosphopantetheine attachment site 3568 3639 0.0089 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SMART SM00823 Phosphopantetheine attachment site 647 718 1.3E-6 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SMART SM00823 Phosphopantetheine attachment site 2150 2217 1.1E-6 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 904 1161 3.56E-25 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.30.300.30 537 654 6.0E-33 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:3.30.300.30 3453 3570 6.2E-27 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3594 3609 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF56801 1571 2132 2.62E-142 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00668 Condensation domain 2619 2908 4.9E-50 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00668 Condensation domain 2269 2502 6.2E-21 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00668 Condensation domain 750 1023 2.1E-18 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00668 Condensation domain 1192 1473 4.0E-46 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3080 3481 2.0E-108 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1649 2064 1.6E-123 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 166 566 8.3E-119 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF47336 2147 2227 1.44E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF47336 3562 3637 4.19E-14 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF56801 3050 3580 3.92E-125 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1036 1185 5.5E-33 T 16-09-2016 IPR010060 Non-ribosomal peptide synthase Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:2.30.38.10 452 532 8.6E-25 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:2.30.38.10 3369 3447 4.2E-24 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Gene3D G3DSA:2.30.38.10 1950 2030 4.1E-23 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 SUPERFAMILY SSF52777 2398 2617 1.11E-18 T 16-09-2016 Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00550 Phosphopantetheine attachment site 3570 3635 2.8E-12 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00550 Phosphopantetheine attachment site 2152 2213 7.7E-8 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 Pfam PF00550 Phosphopantetheine attachment site 652 712 7.2E-13 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31095 79704ed1b7168c782fffd6a2d4afc7d3 3639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 284 295 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 SUPERFAMILY SSF51445 146 586 2.41E-133 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 Pfam PF00128 Alpha amylase, catalytic domain 196 537 2.5E-12 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 20 105 2.7E-18 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 SMART SM00642 165 575 3.1E-10 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 PANTHER PTHR10357:SF74 2 586 0.0 T 16-09-2016 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 PANTHER PTHR10357:SF74 617 709 0.0 T 16-09-2016 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 Gene3D G3DSA:2.60.40.10 16 158 8.4E-54 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 16 708 1.1E-296 T 16-09-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 SUPERFAMILY SSF51011 599 707 3.09E-25 T 16-09-2016 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 PANTHER PTHR10357 2 586 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 PANTHER PTHR10357 617 709 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 SUPERFAMILY SSF81296 16 154 7.56E-42 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 Gene3D G3DSA:3.20.20.80 159 583 2.2E-126 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS01985 86a455756ca7fa0474fdaeac319a9e2d 715 Gene3D G3DSA:2.60.40.1180 599 709 6.9E-33 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 PANTHER PTHR23026 156 307 2.2E-30 T 16-09-2016 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 Pfam PF00881 Nitroreductase family 97 287 4.3E-10 T 16-09-2016 IPR029479 Nitroreductase Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 PANTHER PTHR23026:SF111 156 307 2.2E-30 T 16-09-2016 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 Gene3D G3DSA:3.40.109.10 2 44 6.8E-20 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 Gene3D G3DSA:3.40.109.10 211 304 6.8E-20 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 PANTHER PTHR23026:SF111 1 14 2.2E-30 T 16-09-2016 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 PANTHER PTHR23026 1 14 2.2E-30 T 16-09-2016 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 SUPERFAMILY SSF55469 208 303 4.51E-9 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03905 488c06637e493366ce5752084dfacdbf 307 SUPERFAMILY SSF55469 94 166 4.51E-9 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 Gene3D G3DSA:3.40.50.2300 193 327 5.6E-51 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PANTHER PTHR30146:SF48 89 345 1.1E-133 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PANTHER PTHR30146:SF48 5 72 1.1E-133 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 SUPERFAMILY SSF47413 5 63 7.32E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PANTHER PTHR30146 89 345 1.1E-133 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PANTHER PTHR30146 5 72 1.1E-133 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 Gene3D G3DSA:1.10.260.40 6 57 5.9E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 Pfam PF13377 Periplasmic binding protein-like domain 187 345 1.7E-39 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 1.4E-6 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 1.4E-6 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 5.8E-16 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 Gene3D G3DSA:3.40.50.2300 58 192 2.2E-26 T 16-09-2016 Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 SUPERFAMILY SSF53822 86 343 4.71E-64 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS27520 ad1a049d003c7c85a5806e7d14260926 346 SMART SM00354 5 75 1.9E-22 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 69 502 2.5E-80 T 16-09-2016 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Pfam PF01068 ATP dependent DNA ligase domain 186 382 2.7E-43 T 16-09-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 PANTHER PTHR10459 53 505 4.4E-265 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Pfam PF04675 DNA ligase N terminus 72 130 2.7E-7 T 16-09-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Hamap MF_00407 DNA ligase [lig]. 1 508 26.464 T 16-09-2016 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 PANTHER PTHR10459:SF47 53 505 4.4E-265 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:2.40.50.140 367 397 2.7E-4 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:3.30.1490.70 184 212 5.0E-16 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:3.30.1490.70 331 366 5.0E-16 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:3.30.470.30 213 329 2.7E-29 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 SUPERFAMILY SSF56091 180 382 9.59E-47 T 16-09-2016 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 16-09-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Pfam PF04679 ATP dependent DNA ligase C terminal region 401 492 8.1E-16 T 16-09-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:1.10.3260.10 70 183 7.3E-20 T 16-09-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 SUPERFAMILY SSF117018 4 202 1.96E-28 T 16-09-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 Gene3D G3DSA:2.40.50.140 398 504 2.5E-32 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS04340 b498602d78ebdf0b37905a63863435a3 512 SUPERFAMILY SSF50249 384 504 2.23E-29 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 Gene3D G3DSA:3.30.230.40 91 197 1.7E-28 T 16-09-2016 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 PANTHER PTHR23133:SF2 1 197 6.8E-102 T 16-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 SUPERFAMILY SSF54211 88 181 5.06E-30 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 Gene3D G3DSA:3.30.230.40 3 89 1.2E-36 T 16-09-2016 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 16-09-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 PANTHER PTHR23133 1 197 6.8E-102 T 16-09-2016 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 SUPERFAMILY SSF54211 3 86 2.4E-32 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 16-09-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 197 41.091 T 16-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 Spa2297_RS08370 b836231c9465e8c4ca0fac70583f2adc 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 176 1.3E-61 T 16-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 Spa2297_RS10455 90ee9a6e421db7e74f62415df841d31c 195 SUPERFAMILY SSF52218 5 189 5.33E-37 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS10455 90ee9a6e421db7e74f62415df841d31c 195 PANTHER PTHR30543:SF1 4 195 2.0E-54 T 16-09-2016 Spa2297_RS10455 90ee9a6e421db7e74f62415df841d31c 195 PANTHER PTHR30543 4 195 2.0E-54 T 16-09-2016 Spa2297_RS10455 90ee9a6e421db7e74f62415df841d31c 195 Gene3D G3DSA:3.40.50.360 9 185 6.9E-47 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS10455 90ee9a6e421db7e74f62415df841d31c 195 Pfam PF03358 NADPH-dependent FMN reductase 9 149 3.9E-35 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS15230 d8d42b9a920c69c60b058e3b3f7aeb12 226 PANTHER PTHR18901 4 224 9.5E-31 T 16-09-2016 Spa2297_RS15230 d8d42b9a920c69c60b058e3b3f7aeb12 226 Gene3D G3DSA:3.40.50.1000 94 220 3.7E-24 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS15230 d8d42b9a920c69c60b058e3b3f7aeb12 226 SUPERFAMILY SSF56784 4 222 7.27E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS15230 d8d42b9a920c69c60b058e3b3f7aeb12 226 PANTHER PTHR18901:SF14 4 224 9.5E-31 T 16-09-2016 Spa2297_RS15230 d8d42b9a920c69c60b058e3b3f7aeb12 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 98 190 4.2E-13 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 Gene3D G3DSA:3.10.105.10 366 567 2.6E-34 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 Gene3D G3DSA:3.40.190.10 250 365 4.0E-13 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 Gene3D G3DSA:3.90.76.10 83 249 1.6E-25 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 514 5.9E-65 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 PANTHER PTHR30290 1 49 2.0E-171 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 PANTHER PTHR30290 72 589 2.0E-171 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 PIRSF PIRSF002741 13 599 2.5E-52 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 SUPERFAMILY SSF53850 72 589 3.98E-79 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 PANTHER PTHR30290:SF31 72 589 2.0E-171 T 16-09-2016 Spa2297_RS21565 fee5cb4152fa610dc5b9ce3b52ebef41 599 PANTHER PTHR30290:SF31 1 49 2.0E-171 T 16-09-2016 Spa2297_RS02035 de1342bf1ba4133e6e3786c9a07576dd 150 Pfam PF13581 Histidine kinase-like ATPase domain 29 140 3.0E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02035 de1342bf1ba4133e6e3786c9a07576dd 150 Gene3D G3DSA:3.30.565.10 51 147 9.5E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02035 de1342bf1ba4133e6e3786c9a07576dd 150 SUPERFAMILY SSF55874 45 145 6.81E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 Gene3D G3DSA:3.30.450.40 71 247 1.2E-56 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 SMART SM00346 2 89 1.0E-24 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 PANTHER PTHR30136 3 254 2.3E-109 T 16-09-2016 Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 SUPERFAMILY SSF55781 57 243 3.38E-49 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 Gene3D G3DSA:1.10.10.10 2 70 3.0E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 Pfam PF09339 IclR helix-turn-helix domain 4 52 6.4E-14 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 PANTHER PTHR30136:SF2 3 254 2.3E-109 T 16-09-2016 Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.4E-29 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS21120 94f6db7cf876606f05c372e59843794f 254 SUPERFAMILY SSF46785 3 73 1.83E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 107 118 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 SUPERFAMILY SSF54862 35 151 1.76E-26 T 16-09-2016 Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 9 151 28.128 T 16-09-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 Gene3D G3DSA:1.10.1060.10 17 126 6.5E-19 T 16-09-2016 Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 Pfam PF12838 4Fe-4S dicluster domain 61 121 5.0E-11 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 18 145 1.3E-43 T 16-09-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 PANTHER PTHR10849:SF13 12 151 8.3E-59 T 16-09-2016 Spa2297_RS19235 6c1ae9f47568c553934f306e379c3c82 213 PANTHER PTHR10849 12 151 8.3E-59 T 16-09-2016 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 PIRSF PIRSF001587 8 752 6.7E-288 T 16-09-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 471 575 1.5E-22 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 99 201 1.4E-22 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 214 369 8.0E-34 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 589 724 1.0E-17 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 PANTHER PTHR10099:SF2 17 751 0.0 T 16-09-2016 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 SUPERFAMILY SSF55326 22 207 3.74E-50 T 16-09-2016 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 SUPERFAMILY SSF56042 212 442 2.54E-52 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 SUPERFAMILY SSF56042 586 751 8.55E-38 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 PANTHER PTHR10099 17 751 0.0 T 16-09-2016 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 SUPERFAMILY SSF55326 411 581 2.22E-54 T 16-09-2016 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 27 748 3.9E-263 T 16-09-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Gene3D G3DSA:3.30.1330.10 430 578 1.7E-54 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Gene3D G3DSA:3.30.1330.10 59 206 4.2E-51 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15790 55ab4606f646b935d9bc28b2802e20de 752 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 752 309.957 T 16-09-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 SUPERFAMILY SSF53067 402 495 1.5E-9 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 SUPERFAMILY SSF53067 252 301 1.5E-9 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 SUPERFAMILY SSF53067 7 87 1.5E-9 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 PANTHER PTHR11365 378 544 4.8E-103 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 PANTHER PTHR11365 1 348 4.8E-103 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 Gene3D G3DSA:3.30.420.40 3 65 1.4E-5 T 16-09-2016 Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 175 5.3E-30 T 16-09-2016 IPR008040 Hydantoinaseoxoprolinase, N-terminal Spa2297_RS30550 aa3477c2d59aeb5052863a3d19134b67 709 Pfam PF01968 Hydantoinase/oxoprolinase 194 501 3.1E-79 T 16-09-2016 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 SUPERFAMILY SSF103481 56 150 3.4E-10 T 16-09-2016 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 SUPERFAMILY SSF103481 201 303 1.7E-11 T 16-09-2016 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 PANTHER PTHR12715 16 324 2.6E-119 T 16-09-2016 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 Pfam PF00892 EamA-like transporter family 163 297 8.0E-18 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 Pfam PF00892 EamA-like transporter family 24 150 1.9E-15 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04970 47a376502026de9673b9bfde17afab83 327 PANTHER PTHR12715:SF17 16 324 2.6E-119 T 16-09-2016 Spa2297_RS01635 6cbe51fbedd052adc9fa504cb7042a5b 135 SUPERFAMILY SSF103196 5 133 6.8E-33 T 16-09-2016 Spa2297_RS01635 6cbe51fbedd052adc9fa504cb7042a5b 135 Pfam PF03259 Roadblock/LC7 domain 12 104 1.5E-23 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS01635 6cbe51fbedd052adc9fa504cb7042a5b 135 PANTHER PTHR36222 1 135 3.2E-49 T 16-09-2016 Spa2297_RS01635 6cbe51fbedd052adc9fa504cb7042a5b 135 SMART SM00960 12 104 2.6E-25 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS01635 6cbe51fbedd052adc9fa504cb7042a5b 135 Gene3D G3DSA:3.30.450.30 7 130 6.8E-29 T 16-09-2016 Spa2297_RS02865 d3a4d6730cb36ac7b042075fc93e8b92 417 Pfam PF07690 Major Facilitator Superfamily 18 359 6.2E-19 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS02865 d3a4d6730cb36ac7b042075fc93e8b92 417 SUPERFAMILY SSF103473 14 395 2.09E-32 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02865 d3a4d6730cb36ac7b042075fc93e8b92 417 PANTHER PTHR23517 12 416 1.1E-24 T 16-09-2016 Spa2297_RS02865 d3a4d6730cb36ac7b042075fc93e8b92 417 Gene3D G3DSA:1.20.1250.20 208 388 1.7E-8 T 16-09-2016 Spa2297_RS02865 d3a4d6730cb36ac7b042075fc93e8b92 417 Gene3D G3DSA:1.20.1250.20 16 190 5.4E-15 T 16-09-2016 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 PANTHER PTHR30465 2 80 1.5E-78 T 16-09-2016 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 PANTHER PTHR30465:SF10 2 80 1.5E-78 T 16-09-2016 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 SUPERFAMILY SSF161098 381 555 6.21E-11 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 PANTHER PTHR30465:SF10 367 558 1.5E-78 T 16-09-2016 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 305 1.9E-13 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 400 566 6.5E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27610 cc2a6592448f368d1a3da6cd04273231 601 PANTHER PTHR30465 367 558 1.5E-78 T 16-09-2016 Spa2297_RS14535 3647afe88aefb6784d813761c0b7817d 205 PANTHER PTHR38011 1 205 1.4E-53 T 16-09-2016 Spa2297_RS14535 3647afe88aefb6784d813761c0b7817d 205 Gene3D G3DSA:3.40.430.10 3 202 2.8E-38 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS14535 3647afe88aefb6784d813761c0b7817d 205 PANTHER PTHR38011:SF1 1 205 1.4E-53 T 16-09-2016 Spa2297_RS14535 3647afe88aefb6784d813761c0b7817d 205 SUPERFAMILY SSF53597 2 191 1.96E-27 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS14535 3647afe88aefb6784d813761c0b7817d 205 Pfam PF01872 RibD C-terminal domain 3 189 6.9E-20 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 Gene3D G3DSA:3.40.50.2300 13 133 6.5E-43 T 16-09-2016 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 PANTHER PTHR26402:SF556 13 242 7.0E-97 T 16-09-2016 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 Pfam PF00072 Response regulator receiver domain 15 125 1.3E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 PANTHER PTHR26402 13 242 7.0E-97 T 16-09-2016 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 SMART SM00862 165 240 1.5E-27 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 Gene3D G3DSA:1.10.10.10 141 242 2.4E-36 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 240 8.0E-27 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 SUPERFAMILY SSF52172 14 198 1.26E-44 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS15405 3294b1f4f7e436575728ebd542222f3a 246 SMART SM00448 13 124 1.6E-46 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 PANTHER PTHR22926 1 212 3.0E-155 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 PANTHER PTHR22926 232 360 3.0E-155 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 Pfam PF00953 Glycosyl transferase family 4 89 282 2.3E-37 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 352 2.0E-97 T 16-09-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 16-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 PANTHER PTHR22926:SF5 1 212 3.0E-155 T 16-09-2016 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 ProSitePatterns PS01348 MraY family signature 2. 181 192 - T 16-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 8.2E-6 T 16-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 PANTHER PTHR22926:SF5 232 360 3.0E-155 T 16-09-2016 Spa2297_RS08540 3d794fac5e358e6d72dd96221f1dba37 363 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 356 24.267 T 16-09-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 110 265 6.2E-22 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 PANTHER PTHR11910 110 270 2.7E-37 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 6.1E-7 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 6.1E-7 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 87 271 15.45 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 108 266 5.9E-34 T 16-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 231 250 - T 16-09-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 SUPERFAMILY SSF47928 108 196 3.79E-5 T 16-09-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Spa2297_RS22685 6310445919e88ad7232ae1b5e1766e54 271 Gene3D G3DSA:1.10.520.20 108 196 7.8E-7 T 16-09-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 Gene3D G3DSA:3.50.50.60 121 240 6.9E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 16-09-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 3.0E-120 T 16-09-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PANTHER PTHR22912:SF48 3 307 5.5E-161 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 5.3E-36 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.3E-36 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.3E-36 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 5.3E-36 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.3E-36 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PANTHER PTHR22912 3 307 5.5E-161 T 16-09-2016 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 SUPERFAMILY SSF51905 5 306 1.73E-50 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 1.4E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 287 306 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.2E-82 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 Gene3D G3DSA:3.50.50.60 241 310 8.2E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16525 6406a14e09a9645e9d7bc6754cfe17c0 322 Gene3D G3DSA:3.50.50.60 6 120 8.2E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 249 260 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 Gene3D G3DSA:3.30.300.50 57 110 1.0E-6 T 16-09-2016 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 Gene3D G3DSA:2.40.10.10 197 287 1.5E-28 T 16-09-2016 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PIRSF PIRSF001134 12 300 1.0E-89 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 Gene3D G3DSA:2.40.10.10 116 196 1.8E-27 T 16-09-2016 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 Pfam PF02983 Alpha-lytic protease prodomain 45 99 4.1E-10 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 143 157 7.5E-47 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 265 279 7.5E-47 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 220 237 7.5E-47 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 199 219 7.5E-47 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 240 263 7.5E-47 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 Pfam PF00089 Trypsin 116 292 2.8E-10 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 145 150 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS06855 c51880b169bc94e2828404fcd7dcc747 300 SUPERFAMILY SSF50494 122 293 1.01E-35 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS14015 e9f4a8dc08f1c71c986e24b212076de9 567 Pfam PF13556 PucR C-terminal helix-turn-helix domain 501 557 1.4E-20 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS14015 e9f4a8dc08f1c71c986e24b212076de9 567 PANTHER PTHR33744 271 561 1.1E-37 T 16-09-2016 Spa2297_RS14015 e9f4a8dc08f1c71c986e24b212076de9 567 Gene3D G3DSA:1.10.10.60 506 535 1.5E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14015 e9f4a8dc08f1c71c986e24b212076de9 567 PANTHER PTHR33744:SF4 271 561 1.1E-37 T 16-09-2016 Spa2297_RS12650 2e658c28de5d66caab521b3be7f111d9 681 SUPERFAMILY SSF52540 235 494 1.33E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12650 2e658c28de5d66caab521b3be7f111d9 681 Gene3D G3DSA:3.40.50.300 276 456 7.2E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12650 2e658c28de5d66caab521b3be7f111d9 681 PANTHER PTHR22683 92 489 4.4E-53 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 PANTHER PTHR11911 306 500 1.4E-226 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SMART SM00116 165 213 3.9E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SMART SM00116 104 152 2.7E-8 T 16-09-2016 IPR000644 CBS domain Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 Gene3D G3DSA:3.20.20.70 12 499 2.0E-194 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SMART SM01240 15 487 0.0 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SUPERFAMILY SSF54631 75 211 2.02E-29 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 PANTHER PTHR11911:SF6 1 288 1.4E-226 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 302 314 - T 16-09-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 Pfam PF00571 CBS domain 101 148 4.3E-8 T 16-09-2016 IPR000644 CBS domain Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 Pfam PF00571 CBS domain 157 212 7.5E-6 T 16-09-2016 IPR000644 CBS domain Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 3.3E-181 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 PANTHER PTHR11911 1 288 1.4E-226 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 500 82.684 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 PIRSF PIRSF000130 8 502 4.8E-201 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 PANTHER PTHR11911:SF6 306 500 1.4E-226 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SUPERFAMILY SSF51412 11 98 9.94E-119 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 SUPERFAMILY SSF51412 224 491 9.94E-119 T 16-09-2016 Spa2297_RS20120 99cbf49a4d2cce808dc6093855ead89f 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 487 2.7E-156 T 16-09-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Pfam PF01709 Transcriptional regulator 5 238 1.6E-86 T 16-09-2016 IPR002876 Transcriptional regulator TACO1-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Gene3D G3DSA:1.10.10.200 1 77 8.7E-31 T 16-09-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 SUPERFAMILY SSF75625 3 247 4.71E-89 T 16-09-2016 IPR029072 YebC-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 PANTHER PTHR12532 1 242 9.7E-104 T 16-09-2016 IPR002876 Transcriptional regulator TACO1-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Gene3D G3DSA:3.30.70.980 138 205 1.8E-23 T 16-09-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.076 T 16-09-2016 IPR002876 Transcriptional regulator TACO1-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 9.4E-98 T 16-09-2016 IPR002876 Transcriptional regulator TACO1-like Spa2297_RS05765 513a888046527c465047184afb97d13b 250 PANTHER PTHR12532:SF0 1 242 9.7E-104 T 16-09-2016 Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Gene3D G3DSA:3.30.1270.10 213 248 7.0E-40 T 16-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Spa2297_RS05765 513a888046527c465047184afb97d13b 250 Gene3D G3DSA:3.30.1270.10 83 137 7.0E-40 T 16-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 SUPERFAMILY SSF52518 384 549 1.27E-42 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 SUPERFAMILY SSF52467 181 375 1.45E-37 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 PANTHER PTHR18968 6 546 1.1E-171 T 16-09-2016 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Gene3D G3DSA:3.40.50.1220 209 360 8.4E-45 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 16-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 PANTHER PTHR18968:SF116 6 546 1.1E-171 T 16-09-2016 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Gene3D G3DSA:3.40.50.970 26 199 3.4E-50 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 547 1.1E-32 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Gene3D G3DSA:3.40.50.970 383 547 1.7E-43 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 348 3.5E-32 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 197 5.0E-46 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS11710 275b8d0d0e5a3f61d4dc23ef9fc83b84 561 SUPERFAMILY SSF52518 26 199 3.34E-41 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 Pfam PF05193 Peptidase M16 inactive domain 199 380 2.0E-42 T 16-09-2016 IPR007863 Peptidase M16, C-terminal Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 Gene3D G3DSA:3.30.830.10 269 448 2.5E-55 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 16-09-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 SUPERFAMILY SSF63411 34 238 6.42E-59 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 Gene3D G3DSA:3.30.830.10 35 240 1.1E-55 T 16-09-2016 IPR011237 Peptidase M16 domain GO:0046872 Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 PANTHER PTHR11851 35 448 1.1E-130 T 16-09-2016 Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 3.2E-36 T 16-09-2016 IPR011765 Peptidase M16, N-terminal Spa2297_RS24235 23bf909bdc41c60d79c43c486299034d 459 SUPERFAMILY SSF63411 265 450 4.78E-46 T 16-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Pfam PF01546 Peptidase family M20/M25/M40 82 437 1.3E-36 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 PANTHER PTHR11014:SF106 276 437 2.1E-109 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 SUPERFAMILY SSF53187 12 202 8.86E-53 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 SUPERFAMILY SSF53187 349 437 8.86E-53 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 PANTHER PTHR11014:SF106 13 257 2.1E-109 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 155 - T 16-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 SUPERFAMILY SSF55031 288 333 5.08E-9 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 SUPERFAMILY SSF55031 202 244 5.08E-9 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Pfam PF07687 Peptidase dimerisation domain 200 323 3.0E-12 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 PANTHER PTHR11014 13 257 2.1E-109 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 PANTHER PTHR11014 276 437 2.1E-109 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Gene3D G3DSA:3.40.630.10 13 211 6.7E-56 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Gene3D G3DSA:3.40.630.10 374 437 6.7E-56 T 16-09-2016 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 81 90 - T 16-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Gene3D G3DSA:3.30.70.360 212 251 1.3E-20 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS27005 773b6d08065a95e0a34cfad959f1996f 439 Gene3D G3DSA:3.30.70.360 289 330 1.3E-20 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 PANTHER PTHR15680 1 115 8.5E-51 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 8.4E-48 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 Pfam PF01245 Ribosomal protein L19 4 113 5.5E-49 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 28.73 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 SUPERFAMILY SSF50104 3 115 1.81E-44 T 16-09-2016 IPR008991 Translation protein SH3-like domain Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 PIRSF PIRSF002191 1 116 3.6E-48 T 16-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23760 77018f27fe8c461384c4f7335cf3fa09 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 16-09-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23200 f82e5871bf741c928d511d7478f3c659 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 7.1E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23200 f82e5871bf741c928d511d7478f3c659 208 SUPERFAMILY SSF46689 7 79 3.17E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23200 f82e5871bf741c928d511d7478f3c659 208 Gene3D G3DSA:1.10.357.10 5 191 3.4E-32 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23200 f82e5871bf741c928d511d7478f3c659 208 PANTHER PTHR30055:SF39 2 206 1.9E-72 T 16-09-2016 Spa2297_RS23200 f82e5871bf741c928d511d7478f3c659 208 PANTHER PTHR30055 2 206 1.9E-72 T 16-09-2016 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Gene3D G3DSA:3.30.70.1050 3 119 2.3E-36 T 16-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 SUPERFAMILY SSF109998 245 434 3.79E-40 T 16-09-2016 IPR027304 Trigger factor/SurA domain Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Hamap MF_00303 Trigger factor [tig]. 1 425 19.73 T 16-09-2016 IPR005215 Trigger factor GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Gene3D G3DSA:1.10.3120.10 211 394 3.3E-45 T 16-09-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 SUPERFAMILY SSF102735 3 130 1.83E-38 T 16-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 PANTHER PTHR30560:SF3 1 437 1.0E-120 T 16-09-2016 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 9.5E-40 T 16-09-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 PANTHER PTHR30560 1 437 1.0E-120 T 16-09-2016 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 PIRSF PIRSF003095 1 446 1.4E-127 T 16-09-2016 IPR005215 Trigger factor GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 6.5E-43 T 16-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 SUPERFAMILY SSF54534 89 215 8.05E-21 T 16-09-2016 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Gene3D G3DSA:3.10.50.40 157 210 1.2E-5 T 16-09-2016 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 TIGRFAM TIGR00115 tig: trigger factor 12 418 1.1E-122 T 16-09-2016 IPR005215 Trigger factor GO:0015031 Spa2297_RS11080 f11940c50a6177d0d5a082663c3a71a7 465 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 4.9E-7 T 16-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 SUPERFAMILY SSF52540 353 584 1.26E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 PANTHER PTHR24221:SF161 1 322 1.6E-114 T 16-09-2016 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 PANTHER PTHR24221:SF161 338 581 1.6E-114 T 16-09-2016 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 PANTHER PTHR24221 1 322 1.6E-114 T 16-09-2016 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 Gene3D G3DSA:3.40.50.300 356 586 2.9E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 SUPERFAMILY SSF90123 8 300 1.83E-23 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 Pfam PF00005 ABC transporter 372 517 1.1E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 SMART SM00382 381 562 1.5E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 PANTHER PTHR24221 338 581 1.6E-114 T 16-09-2016 Spa2297_RS27810 ffc19f6950dd1ba5deb50a8fc40a7c72 593 Gene3D G3DSA:1.20.1560.10 10 294 2.8E-17 T 16-09-2016 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 PANTHER PTHR24095 27 446 8.0E-52 T 16-09-2016 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 Gene3D G3DSA:3.40.50.980 173 288 4.7E-24 T 16-09-2016 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 Pfam PF13193 AMP-binding enzyme C-terminal domain 376 443 2.5E-10 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 Gene3D G3DSA:3.40.50.980 27 159 5.2E-10 T 16-09-2016 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 Gene3D G3DSA:3.30.300.30 366 447 5.3E-16 T 16-09-2016 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 Pfam PF00501 AMP-binding enzyme 27 366 4.3E-37 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 ProSitePatterns PS00455 Putative AMP-binding domain signature. 139 150 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02690 daaf9c605f44889593a59bf54c10c8d9 467 SUPERFAMILY SSF56801 25 447 5.23E-79 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Gene3D G3DSA:3.40.228.10 91 273 5.6E-62 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Gene3D G3DSA:3.40.50.740 18 90 1.5E-87 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Gene3D G3DSA:3.40.50.740 274 484 1.5E-87 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 PANTHER PTHR11615 18 647 6.4E-198 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 SUPERFAMILY SSF50692 518 641 7.46E-31 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Pfam PF00384 Molybdopterin oxidoreductase 18 438 7.6E-78 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Gene3D G3DSA:2.40.40.20 520 639 2.0E-31 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 SUPERFAMILY SSF53706 17 493 4.71E-164 T 16-09-2016 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 Pfam PF01568 Molydopterin dinucleotide binding domain 529 631 1.5E-25 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS27315 4257eac303e90cf8daf72f48e9473ec0 647 PANTHER PTHR11615:SF112 18 647 6.4E-198 T 16-09-2016 Spa2297_RS14035 a3a714e5256718057d46627ca8a3b32e 135 Gene3D G3DSA:1.10.10.60 18 51 4.9E-4 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14035 a3a714e5256718057d46627ca8a3b32e 135 SUPERFAMILY SSF46955 44 112 5.95E-6 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS14035 a3a714e5256718057d46627ca8a3b32e 135 Gene3D G3DSA:1.10.1660.10 52 113 3.0E-6 T 16-09-2016 Spa2297_RS14035 a3a714e5256718057d46627ca8a3b32e 135 Pfam PF13591 MerR HTH family regulatory protein 44 123 6.6E-10 T 16-09-2016 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SMART SM00387 340 445 1.2E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 PANTHER PTHR24423 175 473 3.4E-45 T 16-09-2016 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SMART SM00304 181 233 1.1E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 Pfam PF00672 HAMP domain 162 229 1.3E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 2.9E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 2.9E-7 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 284 1.1E-8 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 Gene3D G3DSA:3.30.565.10 303 443 3.9E-18 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 Gene3D G3DSA:1.10.287.130 224 285 9.0E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 PANTHER PTHR24423:SF477 175 473 3.4E-45 T 16-09-2016 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 444 2.1E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SUPERFAMILY SSF158472 182 230 2.62E-5 T 16-09-2016 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SMART SM00388 234 292 2.5E-6 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SUPERFAMILY SSF55874 303 441 1.57E-18 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11880 5f84ad9e3c1a3cf629ea7e5114de0d36 477 SUPERFAMILY SSF47384 218 288 1.73E-9 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 Gene3D G3DSA:3.40.50.2300 2 124 6.3E-34 T 16-09-2016 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 Pfam PF00072 Response regulator receiver domain 5 116 3.1E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 SUPERFAMILY SSF52172 2 134 2.99E-31 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 7.7E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 PANTHER PTHR26402 2 215 2.0E-93 T 16-09-2016 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 SMART SM00448 2 116 2.6E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 PANTHER PTHR26402:SF564 2 215 2.0E-93 T 16-09-2016 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 Gene3D G3DSA:1.10.10.10 125 215 7.8E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 SUPERFAMILY SSF46894 143 214 5.1E-21 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS24095 b8dda3c885f1e1aeeb0ef780eabd8c8b 228 SMART SM00421 151 208 1.3E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 Gene3D G3DSA:3.40.190.10 255 306 1.4E-35 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 Gene3D G3DSA:3.40.190.10 29 144 1.4E-35 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 Gene3D G3DSA:3.40.190.120 145 242 4.1E-23 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 PANTHER PTHR30177 34 305 1.4E-32 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 SUPERFAMILY SSF53850 33 305 2.61E-42 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 PANTHER PTHR30177:SF12 34 305 1.4E-32 T 16-09-2016 Spa2297_RS29610 d72c0292235dc8779969b481a3109a7a 307 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 32 300 1.6E-48 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 Gene3D G3DSA:3.40.50.150 8 187 6.3E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 258 1.5E-35 T 16-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 SMART SM00650 21 187 4.7E-63 T 16-09-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 39 66 - T 16-09-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 SUPERFAMILY SSF53335 8 257 4.62E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS25720 7b5f14373c8a4f2319fdf6c0a1192ae4 259 PANTHER PTHR11727 11 259 1.3E-36 T 16-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spa2297_RS24165 67dc90e60393fe345650cdb50a407e7a 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 1.5E-31 T 16-09-2016 IPR007546 Protein of unknown function DUF503 Spa2297_RS24165 67dc90e60393fe345650cdb50a407e7a 97 Gene3D G3DSA:3.30.70.1120 1 96 2.2E-36 T 16-09-2016 IPR007546 Protein of unknown function DUF503 Spa2297_RS24165 67dc90e60393fe345650cdb50a407e7a 97 SUPERFAMILY SSF103007 1 93 1.44E-30 T 16-09-2016 IPR007546 Protein of unknown function DUF503 Spa2297_RS24165 67dc90e60393fe345650cdb50a407e7a 97 PANTHER PTHR36441 2 97 2.4E-34 T 16-09-2016 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 25 208 5.7E-62 T 16-09-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 257 2.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 347 373 2.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 177 2.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 258 274 2.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 188 216 2.0E-48 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PANTHER PTHR23429:SF0 11 507 1.3E-239 T 16-09-2016 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 Gene3D G3DSA:3.40.50.720 21 207 8.6E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 210 505 1.2E-113 T 16-09-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 23 506 1.2E-200 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 198 204 - T 16-09-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PANTHER PTHR23429 11 507 1.3E-239 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 SUPERFAMILY SSF51735 11 211 4.53E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 PIRSF PIRSF000110 9 507 4.4E-179 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 21 506 87.865 T 16-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 Gene3D G3DSA:3.30.360.10 208 505 7.8E-121 T 16-09-2016 Spa2297_RS07810 817e2e8ed82acdb0b3918f7b394fc6fd 507 SUPERFAMILY SSF55347 198 505 2.84E-113 T 16-09-2016 Spa2297_RS03715 3c483feb5af830fc184d6cd4b132a4da 250 Pfam PF07848 PaaX-like protein 16 77 6.3E-18 T 16-09-2016 IPR012906 PaaX-like, N-terminal UniPathway: UPA00930 Spa2297_RS03715 3c483feb5af830fc184d6cd4b132a4da 250 PANTHER PTHR30319 1 245 1.3E-78 T 16-09-2016 Spa2297_RS03715 3c483feb5af830fc184d6cd4b132a4da 250 Pfam PF08223 PaaX-like protein C-terminal domain 94 238 8.2E-14 T 16-09-2016 IPR013225 PaaX-like, C-terminal UniPathway: UPA00930 Spa2297_RS03715 3c483feb5af830fc184d6cd4b132a4da 250 PANTHER PTHR30319:SF1 1 245 1.3E-78 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SMART SM00116 98 146 0.028 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SMART SM00116 157 205 0.002 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SMART SM01240 11 475 1.0E-198 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SUPERFAMILY SSF54631 97 204 1.52E-22 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 Pfam PF00571 CBS domain 99 142 5.0E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 Pfam PF00571 CBS domain 151 203 1.0E-6 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SUPERFAMILY SSF51412 203 474 4.97E-91 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 SUPERFAMILY SSF51412 11 93 4.97E-91 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 1.1E-102 T 16-09-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 7.7E-286 T 16-09-2016 IPR005991 IMP dehydrogenase-related 1 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 PANTHER PTHR11911:SF80 1 280 0.0 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 PANTHER PTHR11911:SF80 298 477 0.0 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 PANTHER PTHR11911 1 280 0.0 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 PANTHER PTHR11911 298 477 0.0 T 16-09-2016 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 PIRSF PIRSF000130 2 480 6.1E-149 T 16-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 Spa2297_RS05510 f9cf6d0696cdc1ebe1f341fe3f1be4e3 480 Gene3D G3DSA:3.20.20.70 9 475 6.3E-138 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS26975 3b151c0dd4749060cf90cb51861e3877 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 146 3.4E-24 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS26975 3b151c0dd4749060cf90cb51861e3877 148 SUPERFAMILY SSF55961 5 141 6.42E-20 T 16-09-2016 Spa2297_RS26975 3b151c0dd4749060cf90cb51861e3877 148 PIRSF PIRSF017371 1 147 4.4E-72 T 16-09-2016 IPR014488 Uncharacterised conserved protein UCP017371 Spa2297_RS26975 3b151c0dd4749060cf90cb51861e3877 148 Gene3D G3DSA:3.30.530.20 3 147 2.0E-6 T 16-09-2016 IPR023393 START-like domain Spa2297_RS02845 1949fe4ca168b809f0c08877965612a0 347 Gene3D G3DSA:3.40.630.30 1 142 1.4E-7 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02845 1949fe4ca168b809f0c08877965612a0 347 SUPERFAMILY SSF55729 3 297 3.11E-9 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02845 1949fe4ca168b809f0c08877965612a0 347 Pfam PF13527 Acetyltransferase (GNAT) domain 38 116 9.5E-7 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Gene3D G3DSA:3.50.50.60 4 84 5.7E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Gene3D G3DSA:3.50.50.60 142 218 5.7E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Gene3D G3DSA:3.50.50.60 321 379 5.7E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 SUPERFAMILY SSF51905 321 379 7.12E-50 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 SUPERFAMILY SSF51905 6 219 7.12E-50 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 PANTHER PTHR13847 3 378 1.2E-93 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 SUPERFAMILY SSF54373 219 321 2.75E-10 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 8.1E-6 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 8.1E-6 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Gene3D G3DSA:3.30.9.10 89 141 2.9E-13 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Gene3D G3DSA:3.30.9.10 219 319 2.9E-13 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 PANTHER PTHR13847:SF189 3 378 1.2E-93 T 16-09-2016 Spa2297_RS27765 b9e875ceb399266ca7f3c514ccb6b831 383 Pfam PF01266 FAD dependent oxidoreductase 8 360 5.0E-63 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS08630 6a806415a7dfec2c08b2e14e7a7f6dfa 121 Pfam PF12728 Helix-turn-helix domain 15 48 7.6E-7 T 16-09-2016 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Pfam PF00005 ABC transporter 19 187 2.8E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Pfam PF00005 ABC transporter 342 471 4.5E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 SUPERFAMILY SSF52540 330 517 2.08E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 PANTHER PTHR19211:SF53 1 529 0.0 T 16-09-2016 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 SMART SM00382 350 515 9.6E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 SMART SM00382 26 232 1.3E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 PANTHER PTHR19211 1 529 0.0 T 16-09-2016 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Pfam PF12848 ABC transporter 230 304 2.2E-6 T 16-09-2016 IPR032781 ABC-transporter extension domain Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Gene3D G3DSA:3.40.50.300 5 102 1.9E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Gene3D G3DSA:3.40.50.300 135 281 1.9E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 Gene3D G3DSA:3.40.50.300 327 516 5.8E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 SUPERFAMILY SSF52540 2 79 6.4E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07350 b1dbe1e60973bfbc43716b74ece9f216 532 SUPERFAMILY SSF52540 128 232 6.4E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01060 241c55d4a23c1ed99f6fde785857a0c3 322 SUPERFAMILY SSF161098 77 309 8.11E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01060 241c55d4a23c1ed99f6fde785857a0c3 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 316 2.2E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01060 241c55d4a23c1ed99f6fde785857a0c3 322 PANTHER PTHR30193 7 320 3.1E-130 T 16-09-2016 Spa2297_RS01060 241c55d4a23c1ed99f6fde785857a0c3 322 PANTHER PTHR30193:SF6 7 320 3.1E-130 T 16-09-2016 Spa2297_RS01060 241c55d4a23c1ed99f6fde785857a0c3 322 Gene3D G3DSA:1.10.3720.10 83 316 1.2E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Pfam PF13247 4Fe-4S dicluster domain 178 274 2.3E-36 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938:SF8 1 31 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938:SF8 133 142 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938:SF8 173 358 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938 1 31 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938 133 142 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 PANTHER PTHR11938 173 358 2.9E-125 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 177 198 1.5E-10 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 10 26 1.5E-10 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 107 108 1.5E-10 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 361 441 7.3E-28 T 16-09-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:1.10.3650.10 362 440 2.1E-26 T 16-09-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 3 491 1.1E-219 T 16-09-2016 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 239 361 5.0E-68 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 442 466 5.0E-68 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 Gene3D G3DSA:3.30.70.20 199 238 8.6E-25 T 16-09-2016 Spa2297_RS27225 64f391ea38d0d44529ace77ab39c944c 531 SUPERFAMILY SSF54862 1 489 2.2E-156 T 16-09-2016 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 PANTHER PTHR11019:SF56 2 110 1.3E-37 T 16-09-2016 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 SUPERFAMILY SSF55136 126 288 7.32E-23 T 16-09-2016 IPR011256 Regulatory factor, effector binding domain Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 Pfam PF12833 Helix-turn-helix domain 25 103 3.4E-16 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 PANTHER PTHR11019 2 110 1.3E-37 T 16-09-2016 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 SUPERFAMILY SSF46689 4 53 1.52E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 Gene3D G3DSA:3.20.80.10 126 288 1.7E-16 T 16-09-2016 IPR011256 Regulatory factor, effector binding domain Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 Gene3D G3DSA:1.10.10.60 56 118 3.2E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 56 98 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 SUPERFAMILY SSF46689 55 105 3.4E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 SMART SM00342 19 102 1.3E-20 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 Pfam PF06445 GyrI-like small molecule binding domain 126 286 3.8E-24 T 16-09-2016 IPR029442 GyrI-like small molecule binding domain Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 Gene3D G3DSA:1.10.10.60 4 55 1.1E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15125 92257c1970f4c28a76f4b322408a294f 289 SMART SM00871 126 287 2.2E-24 T 16-09-2016 IPR010499 Bacterial transcription activator, effector binding Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 PANTHER PTHR11908:SF71 5 704 0.0 T 16-09-2016 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 SUPERFAMILY SSF56003 118 697 8.77E-156 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 551 695 3.4E-54 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 346 432 3.4E-54 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 114 165 8.9E-8 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 273 299 8.9E-8 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 SMART SM01008 22 126 2.0E-28 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 SUPERFAMILY SSF54665 6 133 2.62E-31 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 PANTHER PTHR11908 5 704 0.0 T 16-09-2016 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 166 265 4.6E-35 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.90.1170.50 4 113 2.5E-29 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 125 3.9E-17 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 636 7.3E-109 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS30240 1d1b68e993eaf0a864c402215934ffa8 709 Gene3D G3DSA:3.30.365.10 433 526 1.3E-23 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS13395 190f9cb474ff3aa4d00c798d1828b173 306 Pfam PF12811 Bax inhibitor 1 like 24 303 2.5E-80 T 16-09-2016 IPR010539 Protein of unknown function UCP009160 Spa2297_RS13395 190f9cb474ff3aa4d00c798d1828b173 306 PIRSF PIRSF009160 1 306 9.1E-103 T 16-09-2016 IPR010539 Protein of unknown function UCP009160 Spa2297_RS13395 190f9cb474ff3aa4d00c798d1828b173 306 PANTHER PTHR41282 33 306 1.7E-99 T 16-09-2016 Spa2297_RS13395 190f9cb474ff3aa4d00c798d1828b173 306 PANTHER PTHR41282:SF1 33 306 1.7E-99 T 16-09-2016 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 8.2E-13 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 Gene3D G3DSA:3.30.360.10 128 298 2.3E-57 T 16-09-2016 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 SUPERFAMILY SSF51735 1 136 9.94E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 PANTHER PTHR22604:SF126 1 299 4.3E-113 T 16-09-2016 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 SUPERFAMILY SSF55347 123 258 1.18E-35 T 16-09-2016 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 PANTHER PTHR22604 1 299 4.3E-113 T 16-09-2016 Spa2297_RS04890 1fbb88a327d338f1c37858c3523c3053 301 Gene3D G3DSA:3.40.50.720 1 127 2.9E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 Pfam PF07690 Major Facilitator Superfamily 32 428 9.3E-29 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 Gene3D G3DSA:1.20.1250.20 25 205 4.6E-18 T 16-09-2016 Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 PANTHER PTHR23501 24 479 9.9E-73 T 16-09-2016 Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 SUPERFAMILY SSF103473 26 214 1.1E-44 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 SUPERFAMILY SSF103473 262 477 1.1E-44 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02475 44cafec21b69bda56c6df1237aecfc7c 479 Gene3D G3DSA:1.20.1250.20 271 477 8.3E-16 T 16-09-2016 Spa2297_RS03845 b9bab0c2b1a4e03d397bc9819ebff521 186 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 35 178 3.1E-22 T 16-09-2016 IPR009936 Protein of unknown function DUF1468 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 PANTHER PTHR19211 1 548 0.0 T 16-09-2016 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Pfam PF12848 ABC transporter 198 254 5.2E-7 T 16-09-2016 IPR032781 ABC-transporter extension domain Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Pfam PF00005 ABC transporter 306 447 2.2E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Pfam PF00005 ABC transporter 21 159 2.4E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Gene3D G3DSA:3.40.50.300 289 519 1.3E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 SUPERFAMILY SSF52540 295 488 1.19E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 PANTHER PTHR19211:SF55 1 548 0.0 T 16-09-2016 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 SUPERFAMILY SSF52540 5 208 7.8E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Pfam PF16326 ABC transporter C-terminal domain 542 603 6.7E-8 T 16-09-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 Gene3D G3DSA:3.40.50.300 7 251 1.3E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 SMART SM00382 30 204 7.5E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS13685 892c0a4743ea54beb31dbe3214840260 605 SMART SM00382 315 491 1.1E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Pfam PF14684 Tricorn protease C1 domain 676 743 7.1E-30 T 16-09-2016 IPR028204 Tricorn protease C1 domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:2.130.10.10 9 161 1.3E-31 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:2.130.10.10 333 656 2.7E-75 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:2.130.10.10 237 275 2.7E-75 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF52096 674 752 5.8E-68 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF52096 845 1054 5.8E-68 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 PANTHER PTHR32060:SF12 1 512 0.0 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SMART SM00245 835 1028 7.1E-15 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 PANTHER PTHR32060 1 512 0.0 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 PANTHER PTHR32060 528 1061 0.0 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:3.30.750.44 673 743 3.4E-33 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF69304 14 267 4.05E-31 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF69304 540 648 9.94E-20 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF69304 369 495 9.94E-20 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 PANTHER PTHR32060:SF12 528 1061 0.0 T 16-09-2016 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 SUPERFAMILY SSF50156 754 835 5.17E-14 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Pfam PF14685 Tricorn protease PDZ domain 754 841 9.5E-28 T 16-09-2016 IPR029414 Tricorn protease, PDZ domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:2.30.42.10 752 849 4.3E-27 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 PIRSF PIRSF036421 1 1061 0.0 T 16-09-2016 IPR012393 Tricorn protease GO:0008236 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Pfam PF03572 Peptidase family S41 873 1027 1.0E-22 T 16-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Gene3D G3DSA:3.90.226.10 853 1059 1.6E-37 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Pfam PF07676 WD40-like Beta Propeller Repeat 469 493 0.014 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS10735 7e6d5d932aaefcb0518df4c75a69c29a 1071 Pfam PF07676 WD40-like Beta Propeller Repeat 51 72 8.8E-5 T 16-09-2016 IPR011659 WD40-like Beta Propeller Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 SUPERFAMILY SSF52540 121 257 8.36E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 SUPERFAMILY SSF52540 10 76 8.36E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:1.25.40.10 706 758 2.1E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:1.25.40.10 796 906 2.1E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:1.25.40.10 533 671 2.1E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:1.10.10.10 917 983 1.4E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 937 953 9.4E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 923 937 9.4E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 953 965 9.4E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:3.40.50.300 121 205 1.7E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Gene3D G3DSA:3.40.50.300 11 76 1.7E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 SMART SM00421 920 977 1.0E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 PANTHER PTHR16305 12 672 1.4E-87 T 16-09-2016 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 PANTHER PTHR16305:SF28 12 672 1.4E-87 T 16-09-2016 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 SUPERFAMILY SSF46894 920 983 5.1E-19 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Pfam PF13191 AAA ATPase domain 12 169 8.8E-29 T 16-09-2016 Spa2297_RS02210 700d23a6b3264f4b7239fbcebf4d6fb9 991 Pfam PF00196 Bacterial regulatory proteins, luxR family 922 977 2.6E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 SUPERFAMILY SSF55083 37 188 7.59E-50 T 16-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 Gene3D G3DSA:3.30.70.560 37 190 3.4E-57 T 16-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 PANTHER PTHR20941:SF10 12 193 5.0E-85 T 16-09-2016 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 124 135 - T 16-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 38 169 3.2E-45 T 16-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 PANTHER PTHR20941 12 193 5.0E-85 T 16-09-2016 Spa2297_RS18195 557d834882dbbc008cae6b7314ddcb6f 203 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 39 169 3.3E-37 T 16-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS03640 08235e7055cada86972e65ba73f42512 227 Gene3D G3DSA:3.20.20.190 3 219 9.8E-61 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS03640 08235e7055cada86972e65ba73f42512 227 PANTHER PTHR23344 6 219 4.8E-59 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS03640 08235e7055cada86972e65ba73f42512 227 SUPERFAMILY SSF51695 3 219 3.14E-61 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS03640 08235e7055cada86972e65ba73f42512 227 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 218 1.9E-33 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 SUPERFAMILY SSF46934 3 55 1.31E-15 T 16-09-2016 IPR009060 UBA-like GO:0005515 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Gene3D G3DSA:1.10.286.20 201 244 1.3E-18 T 16-09-2016 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 16-09-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 PANTHER PTHR11741 1 280 1.3E-102 T 16-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 280 2.3E-73 T 16-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 16-09-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Gene3D G3DSA:3.30.479.20 57 150 3.7E-21 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Gene3D G3DSA:3.30.479.20 152 196 2.8E-21 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Gene3D G3DSA:3.30.479.20 245 280 2.8E-21 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Hamap MF_00050 Elongation factor Ts [tsf]. 1 281 63.298 T 16-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 SUPERFAMILY SSF54713 57 147 2.09E-19 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Gene3D G3DSA:1.10.8.10 3 55 7.3E-24 T 16-09-2016 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 Pfam PF00889 Elongation factor TS 73 280 8.6E-64 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS23825 f2b0bb03632b91a97ae3fa919ce4a459 281 SUPERFAMILY SSF54713 150 280 3.14E-37 T 16-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PRINTS PR00127 Clp protease catalytic subunit P signature 108 127 6.3E-48 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PRINTS PR00127 Clp protease catalytic subunit P signature 165 184 6.3E-48 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PRINTS PR00127 Clp protease catalytic subunit P signature 56 76 6.3E-48 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PRINTS PR00127 Clp protease catalytic subunit P signature 87 104 6.3E-48 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 6.3E-48 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 PANTHER PTHR10381 18 194 2.5E-105 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 Pfam PF00574 Clp protease 16 188 1.2E-78 T 16-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 190 39.665 T 16-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 109 122 - T 16-09-2016 IPR033135 ClpP, histidine active site Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 SUPERFAMILY SSF52096 18 188 3.41E-66 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11075 24b78ab3bb6bfbf15e9e069595cbf0d4 201 Gene3D G3DSA:3.90.226.10 17 188 1.2E-77 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 SUPERFAMILY SSF64263 1 117 5.76E-47 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 2.5E-41 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 Pfam PF01196 Ribosomal protein L17 20 116 5.8E-38 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 Gene3D G3DSA:3.90.1030.10 3 117 4.5E-47 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.472 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 PANTHER PTHR14413 1 117 2.6E-57 T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 PANTHER PTHR14413:SF5 1 117 2.6E-57 T 16-09-2016 Spa2297_RS19935 adf03f864ada00f8725627c73b31ffb0 165 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 16-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS25390 631c6a8bccfea2c91d9e061f839cbc53 181 Pfam PF00583 Acetyltransferase (GNAT) family 80 140 1.1E-8 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS25390 631c6a8bccfea2c91d9e061f839cbc53 181 PANTHER PTHR13355:SF5 87 175 3.3E-23 T 16-09-2016 Spa2297_RS25390 631c6a8bccfea2c91d9e061f839cbc53 181 Gene3D G3DSA:3.40.630.30 2 161 2.1E-21 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25390 631c6a8bccfea2c91d9e061f839cbc53 181 SUPERFAMILY SSF55729 3 160 1.08E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25390 631c6a8bccfea2c91d9e061f839cbc53 181 PANTHER PTHR13355 87 175 3.3E-23 T 16-09-2016 Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 PANTHER PTHR23088 1 265 3.5E-70 T 16-09-2016 Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 Pfam PF00795 Carbon-nitrogen hydrolase 2 251 4.3E-37 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 16-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 Gene3D G3DSA:3.60.110.10 1 263 2.6E-66 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 PANTHER PTHR23088:SF27 1 265 3.5E-70 T 16-09-2016 Spa2297_RS17305 1e3102a1bb4a4cdb9baf2b93c4a1aa93 265 SUPERFAMILY SSF56317 1 264 9.55E-63 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SUPERFAMILY SSF50447 230 343 1.94E-9 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SUPERFAMILY SSF54980 541 613 1.2E-5 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR00315 GTP-binding elongation factor signature 8 21 5.3E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR00315 GTP-binding elongation factor signature 90 101 5.3E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR00315 GTP-binding elongation factor signature 54 62 5.3E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR00315 GTP-binding elongation factor signature 74 84 5.3E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR00315 GTP-binding elongation factor signature 126 135 5.3E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SUPERFAMILY SSF54211 423 539 6.07E-16 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SMART SM00889 423 539 2.7E-11 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Gene3D G3DSA:2.40.30.10 257 340 3.0E-8 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Gene3D G3DSA:3.30.70.870 350 420 2.0E-11 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Gene3D G3DSA:3.40.50.300 3 170 1.6E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Pfam PF00009 Elongation factor Tu GTP binding domain 6 245 9.7E-52 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Pfam PF03764 Elongation factor G, domain IV 423 538 7.7E-19 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SUPERFAMILY SSF54980 349 424 8.99E-10 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Pfam PF00679 Elongation factor G C-terminus 541 614 8.8E-6 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 SUPERFAMILY SSF52540 3 245 1.4E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 462 476 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 274 300 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 219 241 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 511 528 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 112 135 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 477 499 7.4E-27 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 Gene3D G3DSA:3.30.230.10 446 542 8.2E-25 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PANTHER PTHR23115 216 608 3.8E-156 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PANTHER PTHR23115 6 167 3.8E-156 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 165 8.0E-27 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PANTHER PTHR23115:SF91 216 608 3.8E-156 T 16-09-2016 Spa2297_RS29790 0e6b81ef818adf8d4c6198aaea67accf 623 PANTHER PTHR23115:SF91 6 167 3.8E-156 T 16-09-2016 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SUPERFAMILY SSF56507 894 1169 1.96E-95 T 16-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 TIGRFAM TIGR02082 metH: methionine synthase 25 1168 0.0 T 16-09-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SUPERFAMILY SSF52242 732 866 7.2E-38 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Pfam PF00809 Pterin binding enzyme 354 590 2.5E-43 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 967 1168 3.4E-41 T 16-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SUPERFAMILY SSF47644 648 730 2.48E-24 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Gene3D G3DSA:3.20.20.330 15 358 1.7E-103 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Gene3D G3DSA:3.20.20.20 359 620 1.8E-83 T 16-09-2016 IPR000489 Pterin-binding domain GO:0042558 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 PANTHER PTHR21091 19 394 1.7E-122 T 16-09-2016 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Gene3D G3DSA:1.10.1240.10 643 728 1.3E-31 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 PIRSF PIRSF000381 12 1170 0.0 T 16-09-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Pfam PF02607 B12 binding domain 652 724 9.5E-26 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SMART SM01018 649 731 2.7E-41 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 PANTHER PTHR21091:SF97 19 394 1.7E-122 T 16-09-2016 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Pfam PF02310 B12 binding domain 737 855 1.2E-20 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Gene3D G3DSA:3.10.196.10 949 1168 2.2E-72 T 16-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Pfam PF02574 Homocysteine S-methyltransferase 28 319 2.0E-65 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 Gene3D G3DSA:3.40.50.280 734 863 3.1E-46 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SUPERFAMILY SSF51717 351 622 1.15E-73 T 16-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Spa2297_RS06435 63fdce95a5be9d2ae73a102972e6f98f 1170 SUPERFAMILY SSF82282 18 393 6.93E-103 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS29410 fdd153140a4fc56abd46968ebb8fd1c2 192 Pfam PF01872 RibD C-terminal domain 6 181 4.9E-16 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS29410 fdd153140a4fc56abd46968ebb8fd1c2 192 Gene3D G3DSA:3.40.430.10 7 188 2.5E-17 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS29410 fdd153140a4fc56abd46968ebb8fd1c2 192 PANTHER PTHR38011 3 191 5.4E-26 T 16-09-2016 Spa2297_RS29410 fdd153140a4fc56abd46968ebb8fd1c2 192 PANTHER PTHR38011:SF2 3 191 5.4E-26 T 16-09-2016 Spa2297_RS29410 fdd153140a4fc56abd46968ebb8fd1c2 192 SUPERFAMILY SSF53597 6 190 2.62E-24 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 PRINTS PR00419 Adrenodoxin reductase family signature 149 163 3.2E-13 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 3.2E-13 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 Gene3D G3DSA:3.50.50.60 100 320 6.9E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 Gene3D G3DSA:3.40.50.720 321 450 2.3E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 Gene3D G3DSA:3.40.50.720 4 99 2.3E-72 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 173 5.6E-8 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 SUPERFAMILY SSF51971 4 215 8.95E-57 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 SUPERFAMILY SSF51971 264 321 8.95E-57 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 PANTHER PTHR11938 1 450 5.4E-148 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 PANTHER PTHR11938:SF4 1 450 5.4E-148 T 16-09-2016 Spa2297_RS30290 19bfeb93038808d7a2b5df6e866d5bbf 454 PIRSF PIRSF000362 1 454 6.5E-162 T 16-09-2016 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 Gene3D G3DSA:3.40.50.2000 253 394 3.5E-32 T 16-09-2016 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 27 413 1.6E-151 T 16-09-2016 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 238 391 3.7E-15 T 16-09-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 PANTHER PTHR11926 19 407 9.3E-56 T 16-09-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 304 345 - T 16-09-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 SUPERFAMILY SSF53756 23 410 2.75E-75 T 16-09-2016 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 PANTHER PTHR11926:SF16 19 407 9.3E-56 T 16-09-2016 Spa2297_RS25725 46203d51dc68accd922f37c28b725804 417 Gene3D G3DSA:3.40.50.2000 23 252 8.2E-15 T 16-09-2016 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 Pfam PF00146 NADH dehydrogenase 24 347 9.2E-123 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 PANTHER PTHR11432:SF3 6 359 3.0E-160 T 16-09-2016 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 17 354 24.314 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 230 243 - T 16-09-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 PANTHER PTHR11432 6 359 3.0E-160 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19230 a20c4e332906ab567033e291fdc2e3b3 458 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 63 78 - T 16-09-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 PANTHER PTHR11986 10 406 4.3E-197 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 PANTHER PTHR11986:SF18 10 406 4.3E-197 T 16-09-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 Pfam PF00202 Aminotransferase class-III 22 404 1.4E-110 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 SUPERFAMILY SSF53383 9 405 3.06E-114 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 Gene3D G3DSA:3.90.1150.10 8 64 1.6E-35 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 Gene3D G3DSA:3.90.1150.10 314 405 1.6E-35 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 Gene3D G3DSA:3.40.640.10 65 310 1.9E-81 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04430 fefbecb39a4d6481fc32605f69aa94ed 406 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 10 404 1.3E-145 T 16-09-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 SUPERFAMILY SSF51011 591 702 1.15E-22 T 16-09-2016 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Gene3D G3DSA:3.20.20.80 152 576 4.3E-117 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 SMART SM00642 177 568 5.6E-7 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Gene3D G3DSA:2.60.40.10 5 151 8.9E-53 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 702 3.8E-299 T 16-09-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 SUPERFAMILY SSF51445 499 576 5.17E-131 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 SUPERFAMILY SSF51445 133 470 5.17E-131 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 1.4E-16 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Gene3D G3DSA:2.60.40.1180 590 703 4.9E-31 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 PANTHER PTHR10357:SF74 1 579 0.0 T 16-09-2016 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 SUPERFAMILY SSF81296 5 147 4.48E-42 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 PANTHER PTHR10357 1 579 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Pfam PF00128 Alpha amylase, catalytic domain 311 527 4.6E-5 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 Pfam PF00128 Alpha amylase, catalytic domain 189 276 1.9E-6 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 PANTHER PTHR10357 608 703 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS25685 37d786abd076a725acc113609a77657b 705 PANTHER PTHR10357:SF74 608 703 0.0 T 16-09-2016 Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 PANTHER PTHR35525:SF3 16 179 3.3E-26 T 16-09-2016 Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 Pfam PF07336 Putative stress-induced transcription regulator 16 121 3.8E-7 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 Pfam PF11706 CGNR zinc finger 128 172 5.6E-16 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 SUPERFAMILY SSF160904 13 171 6.02E-33 T 16-09-2016 Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 Gene3D G3DSA:1.10.3300.10 14 173 7.9E-32 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS00820 f4d5b4efd2d12a0ed444adc840f7689c 179 PANTHER PTHR35525 16 179 3.3E-26 T 16-09-2016 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 SUPERFAMILY SSF51338 4 67 1.48E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 SUPERFAMILY SSF51338 350 390 1.48E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 PANTHER PTHR22642:SF1 53 387 1.4E-108 T 16-09-2016 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 PANTHER PTHR22642 53 387 1.4E-108 T 16-09-2016 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 TIGRFAM TIGR01224 hutI: imidazolonepropionase 30 387 2.8E-107 T 16-09-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 Gene3D G3DSA:2.30.40.10 6 76 2.7E-12 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 Gene3D G3DSA:3.20.20.140 77 367 7.2E-45 T 16-09-2016 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 390 42.743 T 16-09-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 Pfam PF01979 Amidohydrolase family 64 368 1.9E-25 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS13315 77bc859b1e88bbd386f60bc10f2c2f1f 391 SUPERFAMILY SSF51556 66 349 5.21E-69 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 SUPERFAMILY SSF52540 1 192 4.38E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 27.226 T 16-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 Gene3D G3DSA:3.40.50.300 1 197 1.9E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 186 3.1E-48 T 16-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 PANTHER PTHR10695 1 198 5.7E-74 T 16-09-2016 Spa2297_RS08095 fe767458de22e5019c332e02cb30c056 206 Pfam PF01121 Dephospho-CoA kinase 4 178 3.0E-56 T 16-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 PANTHER PTHR24362:SF160 51 277 3.2E-51 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 PANTHER PTHR24362:SF160 1 27 3.2E-51 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 SMART SM00220 5 280 3.2E-27 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 SUPERFAMILY SSF56112 2 277 5.93E-47 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 Gene3D G3DSA:3.30.200.20 3 152 1.1E-17 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 PANTHER PTHR24362 51 277 3.2E-51 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 PANTHER PTHR24362 1 27 3.2E-51 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 Gene3D G3DSA:1.10.510.10 153 275 2.0E-21 T 16-09-2016 Spa2297_RS22555 4a0b1c7b259362d041e77135c748d2db 455 Pfam PF00069 Protein kinase domain 55 238 1.4E-23 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 Gene3D G3DSA:3.90.1150.10 242 365 5.7E-22 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 Gene3D G3DSA:3.40.640.10 43 241 2.5E-42 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 8 364 3.0E-184 T 16-09-2016 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 PANTHER PTHR11751:SF354 14 365 3.7E-138 T 16-09-2016 Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 SUPERFAMILY SSF53383 4 365 6.86E-82 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 Pfam PF00155 Aminotransferase class I and II 30 363 4.5E-42 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS21650 416c9dc0fdea9378ac9e633e1137879f 365 PANTHER PTHR11751 14 365 3.7E-138 T 16-09-2016 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 PRINTS PR00773 GrpE protein signature 169 188 4.6E-25 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 PRINTS PR00773 GrpE protein signature 95 110 4.6E-25 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 PRINTS PR00773 GrpE protein signature 67 83 4.6E-25 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 PRINTS PR00773 GrpE protein signature 142 157 4.6E-25 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 Pfam PF01025 GrpE 44 190 4.7E-35 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 Gene3D G3DSA:2.30.22.10 134 191 3.9E-22 T 16-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 Gene3D G3DSA:3.90.20.20 44 132 2.1E-19 T 16-09-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 SUPERFAMILY SSF58014 48 134 1.29E-17 T 16-09-2016 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 SUPERFAMILY SSF51064 136 191 4.58E-16 T 16-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 ProSitePatterns PS01071 grpE protein signature. 145 188 - T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 PANTHER PTHR21237 42 194 1.9E-42 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS17485 8de7ada74b109d6f07e5df6999ba4bef 224 Hamap MF_01151 Protein GrpE [grpE]. 21 190 17.283 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS08775 078bee20ae5e243892f674c50aac9f3b 413 Pfam PF09594 Protein of unknown function (DUF2029) 66 309 3.1E-15 T 16-09-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 Spa2297_RS08775 078bee20ae5e243892f674c50aac9f3b 413 PIRSF PIRSF010361 1 412 7.3E-94 T 16-09-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Pfam PF13193 AMP-binding enzyme C-terminal domain 644 717 5.5E-9 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 PANTHER PTHR24095:SF173 156 811 9.6E-174 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Gene3D G3DSA:3.40.50.980 226 388 2.3E-47 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 SMART SM00823 Phosphopantetheine attachment site 745 812 0.0031 T 16-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 ProSitePatterns PS00455 Putative AMP-binding domain signature. 378 389 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 254 660 7.1E-117 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Gene3D G3DSA:2.30.38.10 547 626 1.2E-22 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Pfam PF00501 AMP-binding enzyme 233 636 1.4E-86 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Pfam PF00550 Phosphopantetheine attachment site 747 808 1.5E-11 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Gene3D G3DSA:3.30.300.30 632 748 1.2E-33 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Gene3D G3DSA:1.10.1200.10 749 814 2.2E-20 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 PANTHER PTHR24095 156 811 9.6E-174 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 SUPERFAMILY SSF47336 739 808 1.96E-14 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 SUPERFAMILY SSF56801 203 758 4.45E-147 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 Gene3D G3DSA:3.40.50.980 389 540 5.1E-42 T 16-09-2016 Spa2297_RS00685 23dccc7204f0e64496e17f96bcd5bac1 823 SUPERFAMILY SSF52777 29 201 1.67E-12 T 16-09-2016 Spa2297_RS20400 a4d493411d0707e431f0594bf9e9ebdb 172 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 47 96 1.7E-20 T 16-09-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS20400 a4d493411d0707e431f0594bf9e9ebdb 172 Pfam PF02627 Carboxymuconolactone decarboxylase family 31 112 6.1E-19 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS20400 a4d493411d0707e431f0594bf9e9ebdb 172 Gene3D G3DSA:1.20.1290.10 22 167 2.2E-52 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS20400 a4d493411d0707e431f0594bf9e9ebdb 172 SUPERFAMILY SSF69118 23 164 1.44E-42 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SMART SM00342 126 209 9.2E-20 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 PANTHER PTHR10242:SF3 304 492 3.0E-30 T 16-09-2016 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 PANTHER PTHR10242:SF3 86 277 3.0E-30 T 16-09-2016 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Pfam PF06029 AlkA N-terminal domain 231 357 5.5E-29 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SUPERFAMILY SSF55945 231 338 8.16E-17 T 16-09-2016 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SUPERFAMILY SSF48150 347 483 1.49E-15 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Gene3D G3DSA:1.10.10.60 163 210 1.7E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 PANTHER PTHR10242 304 492 3.0E-30 T 16-09-2016 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 PANTHER PTHR10242 86 277 3.0E-30 T 16-09-2016 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Pfam PF02805 Metal binding domain of Ada 34 97 1.5E-29 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Gene3D G3DSA:3.40.10.10 28 108 9.9E-34 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SMART SM01009 230 357 2.4E-40 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Gene3D G3DSA:1.10.340.30 369 457 1.6E-9 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Pfam PF12833 Helix-turn-helix domain 132 210 4.6E-19 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 163 205 - T 16-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SUPERFAMILY SSF57884 30 109 2.62E-31 T 16-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 SUPERFAMILY SSF46689 163 210 4.48E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Gene3D G3DSA:1.10.1670.10 470 482 8.9E-4 T 16-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spa2297_RS26065 e48ef2b588d0ced1c5dbc73b9c4b6c04 492 Gene3D G3DSA:3.30.310.20 231 357 4.0E-28 T 16-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal Spa2297_RS07775 a7f3d9df50c48d02f7ed363e073188b5 257 PIRSF PIRSF006648 1 256 1.8E-33 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS07775 a7f3d9df50c48d02f7ed363e073188b5 257 PANTHER PTHR30294 19 257 1.2E-61 T 16-09-2016 Spa2297_RS07775 a7f3d9df50c48d02f7ed363e073188b5 257 Pfam PF01061 ABC-2 type transporter 31 224 8.9E-24 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS07775 a7f3d9df50c48d02f7ed363e073188b5 257 PANTHER PTHR30294:SF21 19 257 1.2E-61 T 16-09-2016 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 Pfam PF07728 AAA domain (dynein-related subfamily) 80 224 8.1E-37 T 16-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 Gene3D G3DSA:3.40.50.300 63 235 5.3E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 PANTHER PTHR22908 317 329 1.2E-50 T 16-09-2016 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 PANTHER PTHR22908:SF67 1 301 1.2E-50 T 16-09-2016 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 PANTHER PTHR22908:SF67 317 329 1.2E-50 T 16-09-2016 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 PANTHER PTHR22908 1 301 1.2E-50 T 16-09-2016 Spa2297_RS27565 9c9eb6db9d21d42c63f73438b0405282 374 SUPERFAMILY SSF52540 60 277 9.73E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 Pfam PF00171 Aldehyde dehydrogenase family 18 478 3.0E-137 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 PANTHER PTHR11699:SF27 2 485 7.0E-277 T 16-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 PANTHER PTHR11699 2 485 7.0E-277 T 16-09-2016 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 1.5E-264 T 16-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 Gene3D G3DSA:3.40.605.10 5 261 3.9E-88 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 Gene3D G3DSA:3.40.309.10 262 451 1.9E-63 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS11540 68414de9b133ec4e8457460eaadf7316 500 SUPERFAMILY SSF53720 3 484 9.03E-147 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 PANTHER PTHR11911:SF107 1 119 8.1E-41 T 16-09-2016 Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 SUPERFAMILY SSF54631 1 123 5.43E-29 T 16-09-2016 Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 Gene3D G3DSA:3.10.580.10 1 121 5.8E-30 T 16-09-2016 Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 Pfam PF00571 CBS domain 3 54 2.3E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 Pfam PF00571 CBS domain 73 121 3.5E-12 T 16-09-2016 IPR000644 CBS domain Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 PANTHER PTHR11911 1 119 8.1E-41 T 16-09-2016 Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 SMART SM00116 10 58 0.068 T 16-09-2016 IPR000644 CBS domain Spa2297_RS22015 f8f22a3990bd8396dacdcad2101167e4 136 SMART SM00116 75 122 4.0E-8 T 16-09-2016 IPR000644 CBS domain Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 Gene3D G3DSA:3.40.50.1820 216 318 1.2E-73 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 Gene3D G3DSA:3.40.50.1820 11 156 1.2E-73 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 SUPERFAMILY SSF49785 291 518 7.86E-47 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 22 273 8.2E-63 T 16-09-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 PANTHER PTHR11731:SF130 1 169 4.1E-82 T 16-09-2016 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 304 502 1.6E-37 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 Gene3D G3DSA:2.60.120.260 329 503 1.2E-46 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 PANTHER PTHR11731 211 310 4.1E-82 T 16-09-2016 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 PANTHER PTHR11731 1 169 4.1E-82 T 16-09-2016 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 SUPERFAMILY SSF53474 12 338 3.62E-68 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 22 493 2.8E-65 T 16-09-2016 IPR005674 CocE/Serine esterase GO:0016787 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 PANTHER PTHR11731:SF130 211 310 4.1E-82 T 16-09-2016 Spa2297_RS00510 6d0e2e29bb5e403ca080e2cf24302174 667 SMART SM00939 291 514 2.2E-69 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 SUPERFAMILY SSF51445 17 490 5.06E-124 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 PANTHER PTHR10357:SF11 14 440 3.5E-171 T 16-09-2016 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 Gene3D G3DSA:3.20.20.80 16 118 3.0E-101 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 Gene3D G3DSA:3.20.20.80 192 490 3.0E-101 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 Pfam PF00128 Alpha amylase, catalytic domain 42 407 4.5E-73 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 PANTHER PTHR10357 14 440 3.5E-171 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 SMART SM00642 27 435 7.3E-124 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 PANTHER PTHR10357:SF11 473 539 3.5E-171 T 16-09-2016 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 Gene3D G3DSA:3.90.400.10 119 191 5.8E-31 T 16-09-2016 Spa2297_RS17060 992a69a0e6cbf3fd9b59327a958d5bc8 556 PANTHER PTHR10357 473 539 3.5E-171 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PANTHER PTHR11735:SF6 6 341 3.8E-133 T 16-09-2016 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PANTHER PTHR11735 6 341 3.8E-133 T 16-09-2016 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 340 59.882 T 16-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 319 6.8E-121 T 16-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 SUPERFAMILY SSF53067 6 316 6.69E-38 T 16-09-2016 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 78 98 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 99 118 2.5E-49 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 Gene3D G3DSA:3.30.420.40 6 146 1.7E-42 T 16-09-2016 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 314 1.1E-93 T 16-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS02720 98e4a56a0f803520f8851469a1729d31 356 Pfam PF00814 Glycoprotease family 26 314 5.3E-91 T 16-09-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 Pfam PF08376 Nitrate and nitrite sensing 132 382 7.3E-43 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 605 711 3.3E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 SMART SM00304 420 490 4.3E-5 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 SMART SM00387 602 713 1.5E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 SUPERFAMILY SSF55874 592 710 7.07E-20 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 Gene3D G3DSA:3.30.565.10 570 714 5.5E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 Pfam PF00672 HAMP domain 401 486 1.2E-18 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423 470 486 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423 511 716 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423 839 963 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423:SF468 470 486 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423:SF468 511 716 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423:SF468 839 963 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423:SF468 414 452 6.1E-126 T 16-09-2016 Spa2297_RS23490 8144807bc5e29a720c1f83b746a4e0ba 1305 PANTHER PTHR24423 414 452 6.1E-126 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115 7 182 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Gene3D G3DSA:3.30.70.240 611 705 4.6E-34 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.2E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.2E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.2E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.2E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.2E-16 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SUPERFAMILY SSF50447 276 416 3.53E-35 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 185 2.2E-34 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115:SF66 266 294 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115:SF66 315 705 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Gene3D G3DSA:2.40.30.10 317 416 1.8E-37 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115 266 294 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115 315 705 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Gene3D G3DSA:3.30.70.870 417 492 6.0E-38 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SUPERFAMILY SSF54980 416 493 2.37E-25 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Pfam PF00009 Elongation factor Tu GTP binding domain 10 292 2.9E-67 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Pfam PF03764 Elongation factor G, domain IV 491 612 8.2E-48 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Gene3D G3DSA:3.40.50.300 7 298 2.4E-105 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SUPERFAMILY SSF52540 7 292 6.23E-104 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Pfam PF14492 Elongation Factor G, domain II 416 490 5.4E-34 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Gene3D G3DSA:3.30.230.10 496 610 1.7E-47 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Pfam PF00679 Elongation factor G C-terminus 614 700 9.1E-30 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Pfam PF03144 Elongation factor Tu domain 2 336 402 4.3E-14 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 PANTHER PTHR23115:SF66 7 182 0.0 T 16-09-2016 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 Hamap MF_00054_B Elongation factor G [fusA]. 7 705 109.506 T 16-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SMART SM00838 614 701 2.7E-57 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SMART SM00889 492 612 8.6E-70 T 16-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SUPERFAMILY SSF54211 491 613 1.19E-40 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 SUPERFAMILY SSF54980 617 704 1.06E-29 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS19675 04a3088e143c481fc97044c7e3cb85cb 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 706 0.0 T 16-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 1.2E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 Gene3D G3DSA:1.10.357.10 67 215 9.0E-45 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 PANTHER PTHR30055 11 215 5.4E-50 T 16-09-2016 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 Gene3D G3DSA:1.10.10.60 19 66 1.2E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 Pfam PF16859 Bacterial transcriptional repressor C-terminal 96 207 5.3E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 SUPERFAMILY SSF46689 19 81 3.19E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 SUPERFAMILY SSF48498 97 215 2.02E-23 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS09515 a77d0b78b5d3c86a8993efca9d6a9c58 215 PANTHER PTHR30055:SF66 11 215 5.4E-50 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 PANTHER PTHR12526:SF353 2 41 1.1E-134 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 PANTHER PTHR12526:SF353 65 380 1.1E-134 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 PANTHER PTHR12526 2 41 1.1E-134 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 PANTHER PTHR12526 65 380 1.1E-134 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 Pfam PF00534 Glycosyl transferases group 1 192 362 2.8E-43 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 SUPERFAMILY SSF53756 5 379 1.69E-75 T 16-09-2016 Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 4.9E-7 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS08770 0016470a434cb9d6839adde2878eda1a 380 Gene3D G3DSA:3.40.50.2000 167 361 2.0E-38 T 16-09-2016 Spa2297_RS17325 caed0cff26925a9bb341a44c02bbf362 299 PANTHER PTHR33824:SF2 4 277 1.5E-113 T 16-09-2016 Spa2297_RS17325 caed0cff26925a9bb341a44c02bbf362 299 SUPERFAMILY SSF55961 111 233 2.08E-17 T 16-09-2016 Spa2297_RS17325 caed0cff26925a9bb341a44c02bbf362 299 PANTHER PTHR33824 4 277 1.5E-113 T 16-09-2016 Spa2297_RS17325 caed0cff26925a9bb341a44c02bbf362 299 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 118 240 1.4E-14 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS17325 caed0cff26925a9bb341a44c02bbf362 299 Gene3D G3DSA:3.30.530.20 113 222 4.8E-7 T 16-09-2016 IPR023393 START-like domain Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 257 939 1.0E-268 T 16-09-2016 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 SUPERFAMILY SSF90123 379 690 5.76E-41 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 Gene3D G3DSA:1.20.1560.10 379 689 4.5E-36 T 16-09-2016 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 PANTHER PTHR24221 190 939 4.8E-241 T 16-09-2016 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 SUPERFAMILY SSF52540 699 937 1.15E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 Pfam PF00005 ABC transporter 722 869 7.0E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 SMART SM00382 731 913 1.2E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 Gene3D G3DSA:3.40.50.300 704 928 8.7E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 PANTHER PTHR24221:SF161 190 939 4.8E-241 T 16-09-2016 Spa2297_RS29930 a0c5b18dc686c6f8f1c851f396d0ace8 940 Pfam PF00664 ABC transporter transmembrane region 396 660 2.5E-20 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS09050 26c9574ce3d5afb1c73d63c182c53f29 171 PANTHER PTHR23091:SF276 1 169 4.5E-40 T 16-09-2016 Spa2297_RS09050 26c9574ce3d5afb1c73d63c182c53f29 171 Pfam PF00583 Acetyltransferase (GNAT) family 54 135 1.2E-17 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS09050 26c9574ce3d5afb1c73d63c182c53f29 171 Gene3D G3DSA:3.40.630.30 5 165 4.1E-33 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09050 26c9574ce3d5afb1c73d63c182c53f29 171 PANTHER PTHR23091 1 169 4.5E-40 T 16-09-2016 Spa2297_RS09050 26c9574ce3d5afb1c73d63c182c53f29 171 SUPERFAMILY SSF55729 3 161 2.23E-34 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25560 2eb7d6cabfc96bf51b1afda81e9a182f 236 PANTHER PTHR30151 7 220 8.7E-67 T 16-09-2016 Spa2297_RS25560 2eb7d6cabfc96bf51b1afda81e9a182f 236 Gene3D G3DSA:1.10.3720.10 18 207 1.8E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25560 2eb7d6cabfc96bf51b1afda81e9a182f 236 SUPERFAMILY SSF161098 13 196 2.75E-24 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25560 2eb7d6cabfc96bf51b1afda81e9a182f 236 PANTHER PTHR30151:SF23 7 220 8.7E-67 T 16-09-2016 Spa2297_RS25560 2eb7d6cabfc96bf51b1afda81e9a182f 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 210 3.8E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 SUPERFAMILY SSF103473 271 492 1.28E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 SUPERFAMILY SSF103473 11 220 1.28E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 444 6.7E-73 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 Pfam PF07690 Major Facilitator Superfamily 35 436 9.1E-49 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 33 57 2.0E-7 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 2.0E-7 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 2.0E-7 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 PANTHER PTHR23501:SF31 13 502 1.5E-248 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 Gene3D G3DSA:1.20.1250.20 285 495 4.5E-14 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 Gene3D G3DSA:1.20.1250.20 24 216 5.9E-32 T 16-09-2016 Spa2297_RS13925 6ba0865f45517de1b8ee29bdf19cfb71 515 PANTHER PTHR23501 13 502 1.5E-248 T 16-09-2016 Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 11 208 3.4E-34 T 16-09-2016 IPR032856 Putative glycogen debranching enzyme, N-terminal Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 SUPERFAMILY SSF48208 239 632 5.26E-56 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 PANTHER PTHR10569 331 639 3.3E-168 T 16-09-2016 IPR010401 Glycogen debranching enzyme GO:0004134|GO:0004135|GO:0005980 KEGG: 00500+3.2.1.33+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 PANTHER PTHR10569:SF1 244 311 3.3E-168 T 16-09-2016 Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 PANTHER PTHR10569 244 311 3.3E-168 T 16-09-2016 IPR010401 Glycogen debranching enzyme GO:0004134|GO:0004135|GO:0005980 KEGG: 00500+3.2.1.33+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spa2297_RS01285 b1948061340a254505584f24a9d0724c 644 PANTHER PTHR10569:SF1 331 639 3.3E-168 T 16-09-2016 Spa2297_RS04860 54780e10558869aa65a10de0ce31196f 262 PANTHER PTHR12677 88 260 4.1E-31 T 16-09-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 Spa2297_RS04860 54780e10558869aa65a10de0ce31196f 262 Pfam PF09335 SNARE associated Golgi protein 107 224 6.7E-24 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS28885 e554eb1f218c456278053fb46cf4b81e 456 SUPERFAMILY SSF75304 3 437 3.01E-103 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS28885 e554eb1f218c456278053fb46cf4b81e 456 PANTHER PTHR11895 7 445 2.7E-95 T 16-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS28885 e554eb1f218c456278053fb46cf4b81e 456 Pfam PF01425 Amidase 25 428 3.4E-77 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS28885 e554eb1f218c456278053fb46cf4b81e 456 Gene3D G3DSA:3.90.1300.10 6 443 1.4E-101 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 Gene3D G3DSA:2.60.200.20 106 181 1.6E-24 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 Pfam PF08044 Domain of unknown function (DUF1707) 13 63 2.6E-15 T 16-09-2016 IPR012551 Protein of unknown function DUF1707 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 PANTHER PTHR23308 111 174 1.5E-14 T 16-09-2016 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 SMART SM00240 109 159 2.0E-14 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 SUPERFAMILY SSF49879 106 188 5.74E-25 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS25670 3c2eaa65e5a0a77d45f7a3808e3e5cb0 194 Pfam PF00498 FHA domain 111 174 3.6E-18 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 PANTHER PTHR19211 3 553 0.0 T 16-09-2016 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 SMART SM00382 346 516 3.7E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 SMART SM00382 30 242 2.9E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 SUPERFAMILY SSF52540 11 241 1.19E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 PANTHER PTHR19211:SF7 3 553 0.0 T 16-09-2016 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Pfam PF12848 ABC transporter 227 299 7.8E-12 T 16-09-2016 IPR032781 ABC-transporter extension domain Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 3.1E-273 T 16-09-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Pfam PF00005 ABC transporter 21 188 8.9E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Pfam PF00005 ABC transporter 338 471 2.8E-21 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Gene3D G3DSA:3.40.50.300 319 532 5.2E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 SUPERFAMILY SSF52540 307 514 8.33E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Gene3D G3DSA:3.40.50.300 138 284 1.8E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11355 8a8d762865b5570ceba46264698d3296 554 Gene3D G3DSA:3.40.50.300 8 105 1.8E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 200 281 8.8E-18 T 16-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 PANTHER PTHR30505:SF0 187 692 3.0E-258 T 16-09-2016 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 143 4.6E-30 T 16-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 Pfam PF02378 Phosphotransferase system, EIIC 337 613 5.8E-18 T 16-09-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 SUPERFAMILY SSF52794 197 294 2.09E-31 T 16-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 130 9.9E-31 T 16-09-2016 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 Gene3D G3DSA:3.40.50.2300 196 295 1.9E-37 T 16-09-2016 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 PANTHER PTHR30505:SF0 41 162 3.0E-258 T 16-09-2016 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 Gene3D G3DSA:3.40.930.10 2 145 2.9E-39 T 16-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 199 282 3.9E-28 T 16-09-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 330 666 3.4E-113 T 16-09-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 PANTHER PTHR30505 41 162 3.0E-258 T 16-09-2016 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 PANTHER PTHR30505 187 692 3.0E-258 T 16-09-2016 Spa2297_RS13910 18c29c2d59a35c7be566e05e6396c7d3 701 SUPERFAMILY SSF55804 2 144 1.44E-31 T 16-09-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 PANTHER PTHR23501:SF15 1 483 1.5E-252 T 16-09-2016 Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 Gene3D G3DSA:1.20.1250.20 262 463 8.9E-20 T 16-09-2016 Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 Gene3D G3DSA:1.20.1250.20 14 190 6.8E-29 T 16-09-2016 Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 SUPERFAMILY SSF103473 247 461 1.83E-58 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 SUPERFAMILY SSF103473 10 201 1.83E-58 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 PANTHER PTHR23501 1 483 1.5E-252 T 16-09-2016 Spa2297_RS01945 5b8fb825d482390f489d6e5730836cb7 484 Pfam PF07690 Major Facilitator Superfamily 17 411 1.2E-46 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS23475 389d722a697f8c810ca68c13dc8d66bf 191 Gene3D G3DSA:3.40.50.300 10 184 9.3E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23475 389d722a697f8c810ca68c13dc8d66bf 191 Pfam PF03029 Conserved hypothetical ATP binding protein 19 186 1.9E-27 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS23475 389d722a697f8c810ca68c13dc8d66bf 191 SUPERFAMILY SSF52540 14 185 1.09E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23475 389d722a697f8c810ca68c13dc8d66bf 191 PANTHER PTHR11711:SF117 16 191 1.8E-59 T 16-09-2016 Spa2297_RS23475 389d722a697f8c810ca68c13dc8d66bf 191 PANTHER PTHR11711 16 191 1.8E-59 T 16-09-2016 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 PRINTS PR00050 Cold shock protein signature 38 56 2.8E-14 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 PRINTS PR00050 Cold shock protein signature 24 33 2.8E-14 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-14 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 16-09-2016 IPR019844 Cold-shock conserved site Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 4.4E-20 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 Gene3D G3DSA:2.40.50.140 3 64 1.2E-23 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 SUPERFAMILY SSF50249 2 65 5.57E-18 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 PANTHER PTHR11544 2 124 4.2E-43 T 16-09-2016 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 SMART SM00357 3 65 2.9E-21 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS14665 58d2255ec0a2fbd7361161a3a617eb13 127 PANTHER PTHR11544:SF43 2 124 4.2E-43 T 16-09-2016 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 46 3.9E-8 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 PANTHER PTHR30146 4 341 2.4E-138 T 16-09-2016 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 SUPERFAMILY SSF53822 72 320 2.1E-26 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 PANTHER PTHR30146:SF26 4 341 2.4E-138 T 16-09-2016 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 Gene3D G3DSA:3.40.50.2300 109 171 1.4E-9 T 16-09-2016 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 Gene3D G3DSA:1.10.260.40 7 46 8.3E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 SMART SM00354 4 71 9.7E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 SUPERFAMILY SSF47413 6 47 2.16E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 Pfam PF13407 Periplasmic binding protein domain 104 296 1.5E-25 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS28515 d1988e520749f5189cac9663203c3cc3 344 Gene3D G3DSA:3.40.50.2300 172 314 2.6E-18 T 16-09-2016 Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 SUPERFAMILY SSF51735 141 280 3.59E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 Pfam PF07885 Ion channel 44 124 1.9E-13 T 16-09-2016 IPR013099 Potassium channel domain Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 PANTHER PTHR16254:SF21 29 306 1.6E-79 T 16-09-2016 Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 Pfam PF02254 TrkA-N domain 146 262 5.6E-26 T 16-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 Gene3D G3DSA:3.40.50.720 137 277 2.7E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 SUPERFAMILY SSF81324 31 158 5.89E-21 T 16-09-2016 Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 Gene3D G3DSA:1.10.287.70 40 133 1.2E-15 T 16-09-2016 Spa2297_RS16835 3d5a528ebd04bbdd3be5fa219cc60a66 365 PANTHER PTHR16254 29 306 1.6E-79 T 16-09-2016 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 16-09-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 PANTHER PTHR10031 12 72 1.8E-16 T 16-09-2016 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 70 3.5E-12 T 16-09-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 SUPERFAMILY SSF81333 15 73 1.57E-15 T 16-09-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 PRINTS PR00124 ATP synthase C subunit signature 50 74 1.5E-16 T 16-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.5E-16 T 16-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.5E-16 T 16-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 Pfam PF00137 ATP synthase subunit C 17 71 2.0E-11 T 16-09-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 74 11.665 T 16-09-2016 Spa2297_RS22675 2dc6978651734ef9d10538c9d2a26ef4 74 Gene3D G3DSA:1.20.20.10 15 73 1.2E-19 T 16-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 SUPERFAMILY SSF54211 2 158 2.35E-39 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 259 6.2E-47 T 16-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 Gene3D G3DSA:3.30.230.10 3 160 2.7E-47 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 PANTHER PTHR20861 8 286 2.8E-78 T 16-09-2016 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 288 28.995 T 16-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 SUPERFAMILY SSF55060 165 282 2.88E-21 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 PANTHER PTHR20861:SF2 8 286 2.8E-78 T 16-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 Pfam PF08544 GHMP kinases C terminal 205 279 7.4E-8 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 PIRSF PIRSF010376 1 297 4.8E-75 T 16-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 Gene3D G3DSA:3.30.70.890 165 281 1.4E-23 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS13690 58da5df54aefaf9cf90ff5e7120be2fd 298 Pfam PF00288 GHMP kinases N terminal domain 88 146 9.3E-5 T 16-09-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 SUPERFAMILY SSF53300 343 514 1.01E-23 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 PANTHER PTHR10579 338 519 1.1E-17 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 SMART SM00327 340 509 1.3E-8 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Gene3D G3DSA:3.40.50.410 344 505 7.9E-15 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Gene3D G3DSA:3.40.190.10 259 307 7.9E-9 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Gene3D G3DSA:3.40.190.10 2 101 7.9E-9 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Gene3D G3DSA:3.40.190.10 162 163 7.9E-9 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 PANTHER PTHR10579:SF43 338 519 1.1E-17 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 SUPERFAMILY SSF53850 41 304 1.38E-15 T 16-09-2016 Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Pfam PF13768 von Willebrand factor type A domain 343 499 6.6E-14 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS21080 6dd79ede44020f647e80a2374eaf3f56 519 Pfam PF13531 Bacterial extracellular solute-binding protein 44 291 5.4E-20 T 16-09-2016 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 240 308 1.2E-13 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 SUPERFAMILY SSF54292 209 311 2.62E-29 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 Gene3D G3DSA:2.40.30.10 8 106 3.1E-31 T 16-09-2016 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 Gene3D G3DSA:3.40.50.80 110 213 2.7E-23 T 16-09-2016 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PANTHER PTHR22924:SF20 12 274 1.8E-52 T 16-09-2016 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 267 275 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 Gene3D G3DSA:3.10.20.30 214 315 1.5E-29 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 SUPERFAMILY SSF52343 103 222 3.14E-25 T 16-09-2016 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 SUPERFAMILY SSF63380 10 105 7.35E-25 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 Pfam PF00175 Oxidoreductase NAD-binding domain 117 205 9.4E-6 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 57 71 8.0E-24 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 191 199 8.0E-24 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 95 8.0E-24 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 8.0E-24 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 36 46 8.0E-24 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS11950 7713ee8e6d3e6a7f8488153356b3cb36 318 PANTHER PTHR22924 12 274 1.8E-52 T 16-09-2016 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 SUPERFAMILY SSF47413 32 85 1.42E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 PANTHER PTHR10245:SF7 4 287 1.3E-37 T 16-09-2016 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 PANTHER PTHR10245 4 287 1.3E-37 T 16-09-2016 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 SMART SM00530 36 91 1.2E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 Pfam PF13560 Helix-turn-helix domain 32 92 3.9E-16 T 16-09-2016 Spa2297_RS22535 f7c800cc6074813e3826248bc144b7a8 289 Gene3D G3DSA:1.10.260.40 33 85 4.3E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 PANTHER PTHR18964:SF108 61 277 6.6E-95 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 Pfam PF00480 ROK family 86 397 2.7E-38 T 16-09-2016 IPR000600 ROK family Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 PANTHER PTHR18964 61 277 6.6E-95 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 Gene3D G3DSA:3.30.420.40 82 228 1.3E-30 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 PANTHER PTHR18964 313 399 6.6E-95 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 PANTHER PTHR18964:SF108 313 399 6.6E-95 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 Gene3D G3DSA:3.30.420.40 229 380 4.3E-40 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 SUPERFAMILY SSF53067 83 401 3.34E-45 T 16-09-2016 Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 Gene3D G3DSA:1.10.10.10 11 78 2.7E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27525 c811dbba818a5e75d3a76e2e47cae124 436 SUPERFAMILY SSF46785 12 74 1.05E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16300 29ebc7e9f29eab1fd93f02ad166d0339 124 SUPERFAMILY SSF50891 1 122 2.54E-28 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS16300 29ebc7e9f29eab1fd93f02ad166d0339 124 Pfam PF04126 Cyclophilin-like 1 120 7.8E-37 T 16-09-2016 IPR025658 Cyclophilin TM1367-like domain Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 Gene3D G3DSA:3.40.50.300 17 266 6.6E-84 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 Pfam PF00005 ABC transporter 37 193 2.9E-34 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 PIRSF PIRSF037116 5 270 1.5E-57 T 16-09-2016 IPR012700 Phosphonate C-P lyase system, PhnK Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 PANTHER PTHR24220 19 283 6.8E-130 T 16-09-2016 Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 SUPERFAMILY SSF52540 17 264 9.67E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 282 2.6E-8 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 SMART SM00382 45 250 9.7E-19 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01005 7c9a0d7f06aebb06d02f81714c39266f 292 PANTHER PTHR24220:SF518 19 283 6.8E-130 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 SUPERFAMILY SSF51905 1 322 9.39E-49 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.8E-26 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 1.8E-26 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.8E-26 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.8E-26 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 1.8E-26 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 Gene3D G3DSA:3.50.50.60 5 140 1.5E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 SUPERFAMILY SSF55424 347 457 2.41E-33 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 4.8E-50 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 Gene3D G3DSA:3.30.390.30 336 458 6.3E-35 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 Gene3D G3DSA:3.50.50.60 141 335 4.5E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PIRSF PIRSF000350 1 458 5.6E-99 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PANTHER PTHR22912 4 460 3.5E-162 T 16-09-2016 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 321 2.6E-54 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 453 2.9E-27 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS28755 4411081ded42fb77b10dbb56258d218f 462 PANTHER PTHR22912:SF145 4 460 3.5E-162 T 16-09-2016 Spa2297_RS00460 a18276330685345c74e9d50edcf4ec61 352 SUPERFAMILY SSF48576 48 351 9.78E-33 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS00460 a18276330685345c74e9d50edcf4ec61 352 Gene3D G3DSA:1.10.600.10 31 347 2.3E-56 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 SUPERFAMILY SSF81340 8 415 2.75E-36 T 16-09-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 PRINTS PR00762 Chloride channel signature 100 119 7.4E-5 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 PRINTS PR00762 Chloride channel signature 377 396 7.4E-5 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 PRINTS PR00762 Chloride channel signature 153 172 7.4E-5 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 PRINTS PR00762 Chloride channel signature 331 351 7.4E-5 T 16-09-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Spa2297_RS25060 7c007da5bcd531e7c530c3d98538987d 430 Gene3D G3DSA:1.10.3080.10 9 414 2.4E-19 T 16-09-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 PANTHER PTHR30055 1 185 1.2E-44 T 16-09-2016 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.5E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.5E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 PANTHER PTHR30055:SF2 1 185 1.2E-44 T 16-09-2016 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 Gene3D G3DSA:1.10.357.10 3 185 4.8E-25 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 SUPERFAMILY SSF48498 80 184 1.7E-5 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.1E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23810 bda9efb787ff4512d4137c21559050a6 185 SUPERFAMILY SSF46689 3 75 1.8E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 SUPERFAMILY SSF56784 255 405 3.71E-32 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 PANTHER PTHR21485:SF3 1 405 7.3E-135 T 16-09-2016 Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 PANTHER PTHR21485 1 405 7.3E-135 T 16-09-2016 Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 Pfam PF02348 Cytidylyltransferase 17 146 6.9E-23 T 16-09-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 SUPERFAMILY SSF53448 14 240 1.37E-49 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 Gene3D G3DSA:3.90.550.10 14 241 1.2E-74 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 Gene3D G3DSA:3.40.50.1000 250 404 8.9E-34 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS20650 c94c56afebab17759056442377d8f975 427 Pfam PF08282 haloacid dehalogenase-like hydrolase 332 395 1.3E-8 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS10715 41ffca8d783ed7d57d0536683a8dc98d 448 Gene3D G3DSA:1.20.1250.20 19 167 2.1E-7 T 16-09-2016 Spa2297_RS10715 41ffca8d783ed7d57d0536683a8dc98d 448 Gene3D G3DSA:1.20.1250.20 200 367 1.4E-7 T 16-09-2016 Spa2297_RS10715 41ffca8d783ed7d57d0536683a8dc98d 448 SUPERFAMILY SSF103473 14 377 1.44E-19 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 SUPERFAMILY SSF46894 149 220 5.44E-22 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 2.6E-19 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.8E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 PANTHER PTHR26402:SF151 12 218 6.8E-69 T 16-09-2016 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 SMART SM00421 157 214 2.0E-24 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 Gene3D G3DSA:3.40.50.2300 11 161 4.2E-34 T 16-09-2016 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 SMART SM00448 12 131 1.4E-33 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 PANTHER PTHR26402 12 218 6.8E-69 T 16-09-2016 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 Pfam PF00072 Response regulator receiver domain 14 131 2.5E-22 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 Gene3D G3DSA:1.10.10.10 162 220 5.0E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14895 b09344e02dc27e4b422b43e9388b4f36 221 SUPERFAMILY SSF52172 11 152 3.56E-30 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 PANTHER PTHR10108:SF743 77 371 4.9E-131 T 16-09-2016 Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 Gene3D G3DSA:3.40.50.150 137 415 7.6E-96 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 Pfam PF02353 Mycolic acid cyclopropane synthetase 138 412 7.4E-93 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 PIRSF PIRSF003085 4 433 6.7E-135 T 16-09-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 156 382 4.1E-5 T 16-09-2016 IPR020803 Polyketide synthase, methyltransferase domain Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 PANTHER PTHR10108 77 371 4.9E-131 T 16-09-2016 Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 SUPERFAMILY SSF53335 147 416 7.81E-80 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 PANTHER PTHR10108 395 430 4.9E-131 T 16-09-2016 Spa2297_RS13420 270393a7e0f4920037ebea2845a11078 438 PANTHER PTHR10108:SF743 395 430 4.9E-131 T 16-09-2016 Spa2297_RS24470 5438bf4c27fc17445403225a887e8cbe 412 Pfam PF00999 Sodium/hydrogen exchanger family 19 370 1.4E-48 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS24470 5438bf4c27fc17445403225a887e8cbe 412 PANTHER PTHR16254:SF11 6 387 6.6E-242 T 16-09-2016 Spa2297_RS24470 5438bf4c27fc17445403225a887e8cbe 412 PANTHER PTHR16254 6 387 6.6E-242 T 16-09-2016 Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 PIRSF PIRSF002849 2 330 3.1E-131 T 16-09-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 SUPERFAMILY SSF52540 19 305 8.4E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 Gene3D G3DSA:3.40.50.300 34 198 6.4E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 52 182 4.8E-63 T 16-09-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 PANTHER PTHR11603 17 330 1.1E-148 T 16-09-2016 Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 PANTHER PTHR11603:SF148 17 330 1.1E-148 T 16-09-2016 Spa2297_RS13040 42f005fb5b8d86fc087e402085dacef7 330 Gene3D G3DSA:1.10.8.300 218 326 2.5E-38 T 16-09-2016 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 SUPERFAMILY SSF54631 213 347 9.85E-24 T 16-09-2016 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 SMART SM01091 357 434 1.1E-17 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 Pfam PF00571 CBS domain 290 337 7.0E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 Pfam PF03471 Transporter associated domain 363 432 2.1E-16 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 PANTHER PTHR22777 1 432 3.2E-259 T 16-09-2016 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 PANTHER PTHR22777:SF5 1 432 3.2E-259 T 16-09-2016 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 SUPERFAMILY SSF56176 362 435 1.36E-15 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 Gene3D G3DSA:3.10.580.10 210 331 7.4E-16 T 16-09-2016 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 Gene3D G3DSA:3.30.465.10 332 432 8.6E-23 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS05400 76255906ab77c612d36f780f36952fb4 443 Pfam PF01595 Domain of unknown function DUF21 10 202 3.4E-36 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS04670 7c4d9f93b0da20aaa26cd0a096f950bd 413 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 47 164 1.8E-6 T 16-09-2016 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|UniPathway: UPA00282 Spa2297_RS04670 7c4d9f93b0da20aaa26cd0a096f950bd 413 SUPERFAMILY SSF52777 50 158 4.37E-5 T 16-09-2016 Spa2297_RS04670 7c4d9f93b0da20aaa26cd0a096f950bd 413 SUPERFAMILY SSF52777 213 318 2.39E-5 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 154 183 - T 16-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 16-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 PANTHER PTHR23151 23 579 9.4E-224 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 SUPERFAMILY SSF52777 344 580 1.87E-72 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Pfam PF02817 e3 binding domain 283 315 6.1E-15 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 SUPERFAMILY SSF51230 1 96 3.27E-26 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 PANTHER PTHR23151:SF8 23 579 9.4E-224 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 SUPERFAMILY SSF51230 130 223 9.82E-27 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 SUPERFAMILY SSF47005 275 319 2.22E-12 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 589 6.8E-233 T 16-09-2016 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 354 580 7.9E-69 T 16-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Gene3D G3DSA:3.30.559.10 349 580 1.7E-74 T 16-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Gene3D G3DSA:2.40.50.100 130 223 2.1E-30 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Gene3D G3DSA:2.40.50.100 1 96 1.1E-29 T 16-09-2016 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Gene3D G3DSA:4.10.320.10 279 327 3.4E-19 T 16-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Pfam PF00364 Biotin-requiring enzyme 131 203 1.3E-20 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS09015 44b533d08b0cb1b821c48c6c7fc90e5b 589 Pfam PF00364 Biotin-requiring enzyme 5 76 2.7E-21 T 16-09-2016 IPR000089 Biotin/lipoyl attachment Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 Gene3D G3DSA:1.20.1560.10 73 355 4.9E-8 T 16-09-2016 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 PANTHER PTHR24221 57 642 8.4E-94 T 16-09-2016 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 SMART SM00382 417 609 6.2E-19 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 PANTHER PTHR24221:SF161 57 642 8.4E-94 T 16-09-2016 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 Pfam PF00005 ABC transporter 408 562 2.7E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 SUPERFAMILY SSF52540 385 633 1.41E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 SUPERFAMILY SSF90123 79 354 3.01E-14 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS08020 d72a2ccb23cca76492ed7db35b5e58ad 648 Gene3D G3DSA:3.40.50.300 390 627 1.2E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 Pfam PF13305 WHG domain 84 160 3.1E-6 T 16-09-2016 IPR025996 WHG domain Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 Gene3D G3DSA:1.10.357.10 50 184 8.2E-37 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 SUPERFAMILY SSF46689 6 72 3.29E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 2.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 SUPERFAMILY SSF48498 78 183 8.9E-19 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 Gene3D G3DSA:1.10.10.60 1 49 2.8E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 PANTHER PTHR30055 2 190 1.8E-84 T 16-09-2016 Spa2297_RS25980 edd6421c75010866a4d919bd61833f22 190 PANTHER PTHR30055:SF87 2 190 1.8E-84 T 16-09-2016 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 Gene3D G3DSA:3.40.50.300 355 587 1.4E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 Gene3D G3DSA:1.20.1560.10 23 332 4.7E-68 T 16-09-2016 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 SUPERFAMILY SSF52540 351 591 1.15E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 PANTHER PTHR24221 15 603 2.2E-169 T 16-09-2016 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 Pfam PF00664 ABC transporter transmembrane region 39 306 4.1E-40 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 Pfam PF00005 ABC transporter 375 523 1.2E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 SUPERFAMILY SSF90123 23 333 1.57E-70 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS23055 0ea5c86222ec2a5f4124997a6b7c1ac9 612 SMART SM00382 384 564 1.7E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 SUPERFAMILY SSF63380 92 195 8.5E-34 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 PANTHER PTHR21098 2 199 1.6E-101 T 16-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 Gene3D G3DSA:2.40.30.20 104 197 7.0E-32 T 16-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 Gene3D G3DSA:2.40.30.20 5 103 1.8E-33 T 16-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 PIRSF PIRSF000498 1 202 8.5E-69 T 16-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 194 1.0E-62 T 16-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 SUPERFAMILY SSF63380 2 87 2.13E-24 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 Pfam PF00677 Lumazine binding domain 3 85 1.9E-22 T 16-09-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05435 8e782a885412bbcd1a38048665286732 203 Pfam PF00677 Lumazine binding domain 99 183 1.3E-23 T 16-09-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 Gene3D G3DSA:3.40.50.1820 315 426 1.5E-51 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 Gene3D G3DSA:3.40.50.1820 14 243 1.5E-51 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 2.6E-8 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 2.6E-8 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 2.6E-8 T 16-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PANTHER PTHR10992 330 431 1.4E-149 T 16-09-2016 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 SUPERFAMILY SSF53474 16 230 4.91E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 Pfam PF00561 alpha/beta hydrolase fold 49 235 9.6E-18 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PANTHER PTHR10992:SF888 1 211 1.4E-149 T 16-09-2016 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PANTHER PTHR10992:SF888 330 431 1.4E-149 T 16-09-2016 Spa2297_RS29685 ffa7a7d94495083bd8225761a7d9008b 433 PANTHER PTHR10992 1 211 1.4E-149 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 Gene3D G3DSA:3.50.50.60 296 372 1.7E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 Gene3D G3DSA:3.50.50.60 120 204 1.7E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 Gene3D G3DSA:3.50.50.60 18 83 1.7E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 Pfam PF01494 FAD binding domain 18 372 2.9E-113 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PANTHER PTHR13789 6 374 2.7E-176 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 SUPERFAMILY SSF51905 18 199 2.96E-55 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 SUPERFAMILY SSF51905 295 375 2.96E-55 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PANTHER PTHR13789:SF219 6 374 2.7E-176 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 8.9E-41 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 178 193 8.9E-41 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 8.9E-41 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 359 375 8.9E-41 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 8.9E-41 T 16-09-2016 Spa2297_RS22485 2aeb8c9cafc930b186779dd46b1282ad 640 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 8.9E-41 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 SUPERFAMILY SSF53067 8 219 2.91E-35 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 229 422 1.6E-23 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 PANTHER PTHR10196:SF65 7 479 3.2E-146 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 SUPERFAMILY SSF53067 222 469 4.1E-43 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Gene3D G3DSA:3.30.420.40 7 110 2.4E-19 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Gene3D G3DSA:3.30.420.40 122 219 6.1E-12 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 PANTHER PTHR10196 7 479 3.2E-146 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Gene3D G3DSA:3.30.420.40 224 470 1.7E-41 T 16-09-2016 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 110 6.5E-10 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS31550 879cf2d94cc00fb9a2771ab247ac61a2 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 121 219 7.9E-9 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS16045 49adef7b108955fa6672ccfdcf349199 453 Pfam PF00535 Glycosyl transferase family 2 27 192 1.5E-23 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS16045 49adef7b108955fa6672ccfdcf349199 453 SUPERFAMILY SSF53448 10 236 1.03E-36 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16045 49adef7b108955fa6672ccfdcf349199 453 Pfam PF04138 GtrA-like protein 292 409 5.6E-10 T 16-09-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 Spa2297_RS16045 49adef7b108955fa6672ccfdcf349199 453 PANTHER PTHR10859 7 232 6.5E-55 T 16-09-2016 Spa2297_RS16045 49adef7b108955fa6672ccfdcf349199 453 Gene3D G3DSA:3.90.550.10 24 221 1.0E-20 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 Gene3D G3DSA:2.102.10.10 7 136 8.5E-28 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 Pfam PF00355 Rieske [2Fe-2S] domain 47 125 1.4E-17 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 PANTHER PTHR21496:SF11 1 135 5.4E-58 T 16-09-2016 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 98 110 2.4E-7 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 78 89 2.4E-7 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 111 123 2.4E-7 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 PANTHER PTHR21496 1 135 5.4E-58 T 16-09-2016 Spa2297_RS07885 27eb42eb44f16d7d31a066c76cdd117e 141 SUPERFAMILY SSF50022 8 137 3.14E-28 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS26420 d10e004f41825b216ffc74ed782cdb8a 199 SUPERFAMILY SSF53448 8 195 1.24E-28 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS26420 d10e004f41825b216ffc74ed782cdb8a 199 Gene3D G3DSA:3.90.550.10 6 198 2.2E-29 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS26420 d10e004f41825b216ffc74ed782cdb8a 199 Pfam PF12804 MobA-like NTP transferase domain 10 173 1.6E-33 T 16-09-2016 IPR025877 MobA-like NTP transferase Spa2297_RS26420 d10e004f41825b216ffc74ed782cdb8a 199 PANTHER PTHR19136 3 199 1.9E-50 T 16-09-2016 Spa2297_RS26420 d10e004f41825b216ffc74ed782cdb8a 199 PANTHER PTHR19136:SF78 3 199 1.9E-50 T 16-09-2016 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 Gene3D G3DSA:3.40.50.720 18 96 3.3E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 Gene3D G3DSA:3.40.50.720 420 467 3.3E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 Gene3D G3DSA:3.40.50.720 221 303 3.3E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 322 1.3E-6 T 16-09-2016 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 1.3E-6 T 16-09-2016 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 SUPERFAMILY SSF51905 17 328 1.83E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 SUPERFAMILY SSF51905 427 469 1.83E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 PANTHER PTHR10742:SF243 1 494 8.8E-201 T 16-09-2016 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 PANTHER PTHR10742 1 494 8.8E-201 T 16-09-2016 Spa2297_RS00770 18fe178784d0fccd21082008686b5906 517 Pfam PF01593 Flavin containing amine oxidoreductase 25 467 1.7E-39 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 332 2.2E-28 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 PANTHER PTHR30465:SF69 27 335 2.6E-199 T 16-09-2016 Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 Gene3D G3DSA:1.10.3720.10 115 331 1.0E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 SUPERFAMILY SSF161098 118 316 7.06E-32 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 34 76 2.1E-11 T 16-09-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spa2297_RS23155 e2a440cbbc0c5a0495f0f4bceac41092 335 PANTHER PTHR30465 27 335 2.6E-199 T 16-09-2016 Spa2297_RS26750 c7c5ddcb14290a7adb8d16699cc90118 280 Gene3D G3DSA:3.60.110.10 4 278 7.6E-87 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS26750 c7c5ddcb14290a7adb8d16699cc90118 280 PANTHER PTHR23088 1 280 3.5E-130 T 16-09-2016 Spa2297_RS26750 c7c5ddcb14290a7adb8d16699cc90118 280 SUPERFAMILY SSF56317 3 277 9.16E-80 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS26750 c7c5ddcb14290a7adb8d16699cc90118 280 PANTHER PTHR23088:SF11 1 280 3.5E-130 T 16-09-2016 Spa2297_RS26750 c7c5ddcb14290a7adb8d16699cc90118 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 2.1E-66 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 150 161 8.8E-5 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 33 43 8.8E-5 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 113 132 8.8E-5 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 53 60 8.8E-5 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 Pfam PF00970 Oxidoreductase FAD-binding domain 32 101 3.6E-12 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 SUPERFAMILY SSF63380 4 103 1.29E-20 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 Pfam PF00175 Oxidoreductase NAD-binding domain 114 214 2.3E-10 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 33 45 2.2E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 113 132 2.2E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 200 208 2.2E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 SUPERFAMILY SSF52343 92 230 4.32E-27 T 16-09-2016 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 PANTHER PTHR19370 5 232 4.1E-33 T 16-09-2016 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 Gene3D G3DSA:2.40.30.10 4 93 9.6E-20 T 16-09-2016 Spa2297_RS31380 40ca6b7612fd4f510b2ff1d2b9483171 233 Gene3D G3DSA:3.40.50.80 94 227 1.7E-26 T 16-09-2016 Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 274 3.9E-47 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 PANTHER PTHR10314:SF109 25 347 1.1E-67 T 16-09-2016 Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 PANTHER PTHR10314 25 347 1.1E-67 T 16-09-2016 Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 Gene3D G3DSA:3.40.50.1100 35 135 1.0E-20 T 16-09-2016 Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 Gene3D G3DSA:3.40.50.1100 136 306 1.6E-41 T 16-09-2016 Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 11 307 6.4E-113 T 16-09-2016 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA Spa2297_RS00670 f682d26eb84b2c1891ff5c718eacaef2 347 SUPERFAMILY SSF53686 19 309 6.16E-66 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 PANTHER PTHR21089 7 279 4.1E-71 T 16-09-2016 Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 3.4E-22 T 16-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 Gene3D G3DSA:3.40.50.720 115 276 9.5E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 124 201 1.2E-4 T 16-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 Gene3D G3DSA:3.40.192.10 7 114 2.8E-36 T 16-09-2016 Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 SUPERFAMILY SSF51735 109 270 5.82E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05655 107dbf43d0846954d0cde032d679a34f 279 SUPERFAMILY SSF53223 8 108 5.24E-26 T 16-09-2016 Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 Gene3D G3DSA:3.40.710.10 81 412 1.7E-77 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 Pfam PF05547 Immune inhibitor A peptidase M6 431 585 3.2E-8 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 PANTHER PTHR22935 123 409 1.5E-74 T 16-09-2016 Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 SUPERFAMILY SSF56601 65 412 7.98E-79 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 Pfam PF00144 Beta-lactamase 79 414 8.7E-74 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS02460 aaa702df71050b3dc0a451cceff846a5 591 PANTHER PTHR22935:SF10 123 409 1.5E-74 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 SUPERFAMILY SSF54631 243 379 2.81E-8 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 Gene3D G3DSA:3.30.70.270 375 457 2.6E-17 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 SMART SM00052 1 215 9.7E-9 T 16-09-2016 IPR001633 EAL domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 SMART SM00267 360 530 2.9E-7 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 SUPERFAMILY SSF55073 376 501 4.79E-17 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 Gene3D G3DSA:3.20.20.450 7 214 4.5E-23 T 16-09-2016 IPR001633 EAL domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 454 1.5E-11 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 PANTHER PTHR33121:SF13 51 246 4.1E-31 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 PANTHER PTHR33121 51 246 4.1E-31 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 SUPERFAMILY SSF141868 6 215 7.72E-31 T 16-09-2016 IPR001633 EAL domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 Gene3D G3DSA:3.10.580.10 248 364 3.3E-5 T 16-09-2016 Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 384 455 4.7E-11 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS05155 cd223f9a6682e7c0e08fda9ccc2c4023 541 Pfam PF00563 EAL domain 6 210 5.9E-26 T 16-09-2016 IPR001633 EAL domain Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 SMART SM00060 183 253 6.0E-13 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 SMART SM00636 277 548 2.4E-10 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 SUPERFAMILY SSF49785 37 170 6.8E-11 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Gene3D G3DSA:2.60.120.260 36 141 3.3E-4 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 PANTHER PTHR11177:SF195 248 551 8.3E-53 T 16-09-2016 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Gene3D G3DSA:3.20.20.80 276 556 1.3E-60 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 SUPERFAMILY SSF51445 274 555 1.19E-56 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 SUPERFAMILY SSF49265 180 265 5.44E-19 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 ProSitePatterns PS01095 Chitinases family 18 active site. 385 393 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Pfam PF00704 Glycosyl hydrolases family 18 279 548 5.2E-32 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 PANTHER PTHR11177 248 551 8.3E-53 T 16-09-2016 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Gene3D G3DSA:2.60.40.10 181 261 3.9E-21 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Pfam PF02018 Carbohydrate binding domain 39 153 2.5E-14 T 16-09-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 Spa2297_RS21150 e793ea3eb598ec6e4b1a91ef76d6bca6 567 Pfam PF00041 Fibronectin type III domain 184 256 1.0E-8 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 PANTHER PTHR23508:SF17 4 494 5.4E-290 T 16-09-2016 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 ProSitePatterns PS00217 Sugar transport proteins signature 2. 165 190 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 Gene3D G3DSA:1.20.1250.20 53 255 1.9E-24 T 16-09-2016 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 Gene3D G3DSA:1.20.1250.20 289 476 1.9E-23 T 16-09-2016 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 Pfam PF00083 Sugar (and other) transporter 59 480 1.4E-45 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 PANTHER PTHR23508 4 494 5.4E-290 T 16-09-2016 Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 SUPERFAMILY SSF103473 51 479 1.27E-71 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS04440 1789092cf42fb1105300aceac4038490 504 ProSitePatterns PS00216 Sugar transport proteins signature 1. 346 362 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 Gene3D G3DSA:3.40.190.10 167 264 2.2E-20 T 16-09-2016 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 PANTHER PTHR18966:SF191 37 303 7.4E-83 T 16-09-2016 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 SMART SM00062 67 307 1.7E-51 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 SUPERFAMILY SSF53850 20 304 5.44E-56 T 16-09-2016 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 304 1.7E-64 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 PANTHER PTHR18966 37 303 7.4E-83 T 16-09-2016 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 Gene3D G3DSA:3.40.190.10 64 164 7.5E-36 T 16-09-2016 Spa2297_RS22265 b6fd13ab14c544643d533f2ebc7c0d88 319 Gene3D G3DSA:3.40.190.10 266 305 7.5E-36 T 16-09-2016 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 13 427 7.9E-177 T 16-09-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 243 279 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 Gene3D G3DSA:3.90.1150.10 327 429 1.2E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 Gene3D G3DSA:3.90.1150.10 8 78 1.2E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 PANTHER PTHR11986:SF5 7 438 8.5E-198 T 16-09-2016 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 Gene3D G3DSA:3.40.640.10 79 325 1.5E-75 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 PANTHER PTHR11986 7 438 8.5E-198 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 SUPERFAMILY SSF53383 10 429 1.46E-116 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 12 433 95.211 T 16-09-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18780 7435416948ad8c2a2e79453a66d419cd 438 Pfam PF00202 Aminotransferase class-III 42 426 1.9E-79 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 Gene3D G3DSA:3.40.50.720 192 430 7.9E-63 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 326 354 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PANTHER PTHR24322 339 372 5.0E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PANTHER PTHR24322 201 323 5.0E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 197 376 2.1E-7 T 16-09-2016 Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 SUPERFAMILY SSF51735 94 178 7.24E-5 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 319 327 5.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 339 358 5.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 266 277 5.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 313 329 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 394 414 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 361 378 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 339 358 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 266 277 4.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PANTHER PTHR24322:SF639 339 372 5.0E-44 T 16-09-2016 Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 PANTHER PTHR24322:SF639 201 323 5.0E-44 T 16-09-2016 Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 SUPERFAMILY SSF51735 192 430 9.81E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18890 5ed983ca42b31d5fef937278c77a1e32 434 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 203 428 5.3E-49 T 16-09-2016 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 PANTHER PTHR30011:SF27 1 320 1.2E-120 T 16-09-2016 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 Pfam PF00296 Luciferase-like monooxygenase 8 291 2.4E-56 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 SUPERFAMILY SSF51679 2 319 1.0E-67 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 PANTHER PTHR30011 1 320 1.2E-120 T 16-09-2016 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 Gene3D G3DSA:3.20.20.30 2 319 2.1E-72 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02235 17e6e53b675d1884685dc4c463dad672 325 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 320 9.3E-158 T 16-09-2016 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 177 1.6E-17 T 16-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 Gene3D G3DSA:1.10.3720.10 65 282 1.6E-49 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 280 3.0E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 SUPERFAMILY SSF161098 67 268 5.1E-44 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 PANTHER PTHR30450:SF2 52 291 1.5E-175 T 16-09-2016 Spa2297_RS22260 feebf8291c83c023973c47f27d578972 316 PANTHER PTHR30450 52 291 1.5E-175 T 16-09-2016 Spa2297_RS09920 25b4331b9a2a231b22adca0c7bb4f7b6 261 Pfam PF09335 SNARE associated Golgi protein 43 170 8.4E-21 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS09920 25b4331b9a2a231b22adca0c7bb4f7b6 261 PANTHER PTHR30353:SF13 16 261 3.9E-106 T 16-09-2016 Spa2297_RS09920 25b4331b9a2a231b22adca0c7bb4f7b6 261 PANTHER PTHR30353 16 261 3.9E-106 T 16-09-2016 IPR032818 DedA family Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 Pfam PF01547 Bacterial extracellular solute-binding protein 55 347 1.2E-54 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 SUPERFAMILY SSF53850 27 449 4.08E-71 T 16-09-2016 Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 PANTHER PTHR30061 6 454 2.8E-168 T 16-09-2016 Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 PANTHER PTHR30061:SF3 6 454 2.8E-168 T 16-09-2016 Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 Gene3D G3DSA:3.40.190.10 174 371 1.2E-50 T 16-09-2016 Spa2297_RS07575 5e81686d396bc8c7a22dacee52699c95 456 Gene3D G3DSA:3.40.190.10 53 173 5.4E-20 T 16-09-2016 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 SUPERFAMILY SSF50249 1 66 2.35E-24 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.3E-30 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 PANTHER PTHR11544 1 67 5.6E-40 T 16-09-2016 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 16-09-2016 IPR019844 Cold-shock conserved site Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 PIRSF PIRSF002599 1 67 9.8E-26 T 16-09-2016 IPR012156 Cold shock, CspA GO:0003676 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 Gene3D G3DSA:2.40.50.140 1 65 2.5E-30 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 SMART SM00357 3 67 9.9E-31 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 PRINTS PR00050 Cold shock protein signature 25 34 3.5E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 PRINTS PR00050 Cold shock protein signature 4 19 3.5E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS30985 4bcad5bb5bc091f5a5417936d3a6fd3d 67 PRINTS PR00050 Cold shock protein signature 40 58 3.5E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS16360 079f7a7e3c5fe2d8e41be9e039b3e8ec 128 PANTHER PTHR37309:SF1 2 128 5.0E-45 T 16-09-2016 Spa2297_RS16360 079f7a7e3c5fe2d8e41be9e039b3e8ec 128 PANTHER PTHR37309 2 128 5.0E-45 T 16-09-2016 Spa2297_RS16360 079f7a7e3c5fe2d8e41be9e039b3e8ec 128 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 115 8.2E-32 T 16-09-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV Spa2297_RS05980 235c59a1026dd640fa211256a89eb070 216 PANTHER PTHR18901 6 215 5.7E-53 T 16-09-2016 Spa2297_RS05980 235c59a1026dd640fa211256a89eb070 216 SUPERFAMILY SSF56784 6 205 5.02E-45 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS05980 235c59a1026dd640fa211256a89eb070 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 179 9.8E-19 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS05980 235c59a1026dd640fa211256a89eb070 216 Gene3D G3DSA:3.40.50.1000 66 207 1.6E-47 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS05980 235c59a1026dd640fa211256a89eb070 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 8 179 9.3E-22 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Gene3D G3DSA:3.40.47.10 12 132 1.7E-46 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Gene3D G3DSA:3.40.47.10 219 294 1.7E-46 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Pfam PF02803 Thiolase, C-terminal domain 311 427 2.7E-30 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 PIRSF PIRSF000429 7 428 7.2E-99 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 SUPERFAMILY SSF53901 12 289 4.66E-56 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Gene3D G3DSA:3.40.47.10 174 218 1.6E-42 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Gene3D G3DSA:3.40.47.10 306 427 1.6E-42 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 PANTHER PTHR18919:SF5 7 428 1.2E-173 T 16-09-2016 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 PANTHER PTHR18919 7 428 1.2E-173 T 16-09-2016 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 SUPERFAMILY SSF53901 288 427 3.3E-30 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 Pfam PF00108 Thiolase, N-terminal domain 12 282 9.3E-48 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS18895 80858b2b4fbe091f65e359bdbaefaa69 428 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 14 426 2.1E-112 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 PANTHER PTHR30055 4 195 2.7E-47 T 16-09-2016 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 2.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 SUPERFAMILY SSF46689 4 66 2.05E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 PANTHER PTHR30055:SF73 4 195 2.7E-47 T 16-09-2016 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 Gene3D G3DSA:1.10.357.10 4 180 2.0E-25 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23355 e71cbd4cdd73766dfb8c7626fb0dc252 195 SUPERFAMILY SSF48498 76 178 5.86E-9 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 PANTHER PTHR24220 10 248 2.4E-84 T 16-09-2016 Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 SUPERFAMILY SSF52540 6 224 2.87E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 Gene3D G3DSA:3.40.50.300 4 226 1.8E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 SMART SM00382 33 211 7.4E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 PANTHER PTHR24220:SF414 10 248 2.4E-84 T 16-09-2016 Spa2297_RS25865 72370f2f32f8791a8cd44ca4b89ad9c8 303 Pfam PF00005 ABC transporter 24 162 2.2E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 PANTHER PTHR39515 1 139 9.1E-59 T 16-09-2016 Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 Gene3D G3DSA:1.10.10.10 32 92 3.1E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 SUPERFAMILY SSF46785 15 139 9.54E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 SMART SM00347 22 124 7.9E-13 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 Pfam PF12802 MarR family 30 86 6.2E-10 T 16-09-2016 Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 PANTHER PTHR39515:SF1 1 139 9.1E-59 T 16-09-2016 Spa2297_RS31830 5027ee92fbc97e174392efc2f367b95d 140 Gene3D G3DSA:1.10.287.100 94 140 1.7E-15 T 16-09-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Gene3D G3DSA:3.10.150.10 126 250 3.8E-29 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Gene3D G3DSA:3.10.150.10 2 120 1.6E-31 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 SUPERFAMILY SSF55979 249 374 1.96E-29 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 SMART SM00480 17 370 2.8E-147 T 16-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Gene3D G3DSA:3.10.150.10 252 374 1.9E-38 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 2.7E-36 T 16-09-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 1.2E-33 T 16-09-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 PIRSF PIRSF000804 1 375 1.8E-95 T 16-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 1.5E-38 T 16-09-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 SUPERFAMILY SSF55979 126 247 2.17E-19 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 SUPERFAMILY SSF55979 2 119 1.18E-23 T 16-09-2016 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 5.9E-90 T 16-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS16575 f59c2cbaffeb5d39e45aba9c5bc33c1e 376 PANTHER PTHR30478 2 376 5.8E-121 T 16-09-2016 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 SUPERFAMILY SSF51905 324 384 1.42E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 SUPERFAMILY SSF51905 14 231 1.42E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Pfam PF01266 FAD dependent oxidoreductase 16 364 3.8E-58 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 PANTHER PTHR13847 11 448 9.5E-221 T 16-09-2016 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 SUPERFAMILY SSF54373 232 327 1.12E-9 T 16-09-2016 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Pfam PF04324 BFD-like [2Fe-2S] binding domain 411 465 2.9E-11 T 16-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 PANTHER PTHR13847:SF197 11 448 9.5E-221 T 16-09-2016 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Gene3D G3DSA:3.50.50.60 12 96 1.1E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Gene3D G3DSA:3.50.50.60 334 373 1.1E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Gene3D G3DSA:3.50.50.60 153 230 1.1E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Gene3D G3DSA:3.30.9.10 231 327 1.1E-8 T 16-09-2016 Spa2297_RS28635 7ad88be7298e6666611a91ad47535852 468 Gene3D G3DSA:3.30.9.10 99 152 1.1E-8 T 16-09-2016 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 311 4.8E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 Gene3D G3DSA:3.30.565.10 300 458 1.5E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 SMART SM00304 183 244 1.8E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 SMART SM00388 245 312 4.5E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 SUPERFAMILY SSF55874 301 458 2.36E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 Pfam PF00672 HAMP domain 164 241 5.7E-15 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 SMART SM00387 356 462 9.8E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 457 9.1E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 SUPERFAMILY SSF47384 228 312 3.34E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 PANTHER PTHR24423 177 458 1.5E-64 T 16-09-2016 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 6.8E-11 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS28450 08ffa5cce924e9878af5aceceb9a96dd 468 Gene3D G3DSA:1.10.287.130 235 299 3.1E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS03870 aa2e5ffbf0d846a5d848bb0676937535 95 PANTHER PTHR33677 1 94 1.7E-33 T 16-09-2016 Spa2297_RS03870 aa2e5ffbf0d846a5d848bb0676937535 95 Pfam PF02583 Metal-sensitive transcriptional repressor 11 82 5.7E-25 T 16-09-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Spa2297_RS03870 aa2e5ffbf0d846a5d848bb0676937535 95 PANTHER PTHR33677:SF2 1 94 1.7E-33 T 16-09-2016 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 PANTHER PTHR33280 1 80 1.5E-33 T 16-09-2016 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 SUPERFAMILY SSF143800 1 79 7.46E-20 T 16-09-2016 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 PRINTS PR01249 Ribosomal protein L31 signature 2 19 9.0E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 PRINTS PR01249 Ribosomal protein L31 signature 45 60 9.0E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 PRINTS PR01249 Ribosomal protein L31 signature 60 78 9.0E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 7.8E-18 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 Pfam PF01197 Ribosomal protein L31 1 79 8.7E-28 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.256 T 16-09-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18075 a1346f4262165273b16e3d1a1f35a2f7 83 PANTHER PTHR33280:SF3 1 80 1.5E-33 T 16-09-2016 Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 SUPERFAMILY SSF51735 6 253 9.3E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 PANTHER PTHR24322 12 189 6.6E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 Gene3D G3DSA:3.40.50.720 3 252 9.1E-57 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 5.7E-68 T 16-09-2016 Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 PANTHER PTHR24322:SF317 12 189 6.6E-52 T 16-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 Spa2297_RS07215 2da14bfb02c412409efb69a0c7e8b60d 255 PIRSF PIRSF000094 2 255 4.3E-85 T 16-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 Gene3D G3DSA:1.10.357.10 19 209 1.2E-18 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 PANTHER PTHR30055:SF74 6 115 1.3E-24 T 16-09-2016 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.6E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.6E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 PANTHER PTHR30055 6 115 1.3E-24 T 16-09-2016 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 4.0E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02815 55a12ed8797f80d49aad636052824cc7 224 SUPERFAMILY SSF46689 11 88 1.65E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 PANTHER PTHR10357 168 657 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 PANTHER PTHR10357:SF137 168 657 0.0 T 16-09-2016 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 SUPERFAMILY SSF51011 564 640 8.74E-7 T 16-09-2016 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 Gene3D G3DSA:2.60.40.1180 563 640 1.6E-11 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 SUPERFAMILY SSF51445 202 559 3.41E-82 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 PANTHER PTHR10357 9 134 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 SMART SM00642 201 529 1.8E-4 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 Pfam PF11896 Domain of unknown function (DUF3416) 8 195 6.4E-60 T 16-09-2016 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 6 652 47.308 T 16-09-2016 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 Gene3D G3DSA:3.20.20.80 202 557 4.4E-66 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02000 3350cb5a11599721d1db7065bf16d27f 666 PANTHER PTHR10357:SF137 9 134 0.0 T 16-09-2016 Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 Gene3D G3DSA:2.120.10.30 370 578 5.6E-9 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 351 614 5.8E-58 T 16-09-2016 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 11 615 24.408 T 16-09-2016 IPR023959 Lipoprotein LpqB Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 Pfam PF10646 Sporulation and spore germination 216 319 1.7E-9 T 16-09-2016 IPR019606 GerMN domain Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 SMART SM00909 229 323 1.9E-13 T 16-09-2016 IPR019606 GerMN domain Spa2297_RS13005 4da19ec4ceec6b6e961fa45e6b2d4f8b 615 SUPERFAMILY SSF50969 340 583 1.88E-8 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS21125 4d38bf54382fd51b42e820e5cbee205c 136 SUPERFAMILY SSF55298 6 136 1.88E-30 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS21125 4d38bf54382fd51b42e820e5cbee205c 136 Pfam PF01042 Endoribonuclease L-PSP 15 134 5.2E-25 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS21125 4d38bf54382fd51b42e820e5cbee205c 136 PANTHER PTHR11803 15 136 5.9E-33 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS21125 4d38bf54382fd51b42e820e5cbee205c 136 Gene3D G3DSA:3.30.1330.40 3 135 6.1E-35 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 Pfam PF07690 Major Facilitator Superfamily 19 408 2.6E-52 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 410 3.2E-82 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 SUPERFAMILY SSF103473 203 460 6.8E-27 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 SUPERFAMILY SSF103473 4 194 4.45E-51 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 PANTHER PTHR23501 1 461 4.1E-127 T 16-09-2016 Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 Gene3D G3DSA:1.20.1250.20 13 198 1.7E-37 T 16-09-2016 Spa2297_RS17580 8f38bacb81ea37dc1db39a484c3296c2 487 Gene3D G3DSA:1.20.1250.20 260 465 6.7E-16 T 16-09-2016 Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 Pfam PF00005 ABC transporter 27 164 4.4E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 SUPERFAMILY SSF52540 7 227 5.13E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 Gene3D G3DSA:3.40.50.300 6 228 4.4E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 SMART SM00382 35 221 7.3E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 PANTHER PTHR24220 11 245 5.2E-113 T 16-09-2016 Spa2297_RS15820 94836a8fd4ed07355af6afb86d3745af 330 PANTHER PTHR24220:SF414 11 245 5.2E-113 T 16-09-2016 Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 Pfam PF00583 Acetyltransferase (GNAT) family 55 134 2.0E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 SUPERFAMILY SSF55729 157 301 5.85E-14 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 SUPERFAMILY SSF55729 8 137 9.09E-21 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 Gene3D G3DSA:3.40.630.30 12 147 8.9E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 PANTHER PTHR23091 1 137 5.8E-13 T 16-09-2016 Spa2297_RS06805 2fde27cf8aba690cfb83f0d05baf1962 308 Gene3D G3DSA:3.40.630.30 156 301 2.9E-12 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 104 1.8E-21 T 16-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 100 9.0E-20 T 16-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 PANTHER PTHR33231 1 226 6.3E-69 T 16-09-2016 Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 SUPERFAMILY SSF69754 3 113 5.36E-23 T 16-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 154 207 4.2E-22 T 16-09-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 PANTHER PTHR33231:SF1 1 226 6.3E-69 T 16-09-2016 Spa2297_RS12995 e7920882343ec7cb46f59b8486440b0f 230 Gene3D G3DSA:3.30.160.100 2 100 4.2E-26 T 16-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 Spa2297_RS07380 4dd3ab45e26a66540ee6dade20f24caf 321 PANTHER PTHR34308 1 318 2.0E-100 T 16-09-2016 Spa2297_RS07380 4dd3ab45e26a66540ee6dade20f24caf 321 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 15 263 2.1E-50 T 16-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 Spa2297_RS07380 4dd3ab45e26a66540ee6dade20f24caf 321 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 314 93.378 T 16-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 Spa2297_RS07380 4dd3ab45e26a66540ee6dade20f24caf 321 Pfam PF03186 CobD/Cbib protein 13 292 1.2E-83 T 16-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 Spa2297_RS07380 4dd3ab45e26a66540ee6dade20f24caf 321 PANTHER PTHR34308:SF1 1 318 2.0E-100 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 312 7.5E-150 T 16-09-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 Gene3D G3DSA:3.30.420.40 135 287 7.0E-48 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 PANTHER PTHR18964 2 313 2.6E-100 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 PANTHER PTHR18964:SF108 2 313 2.6E-100 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 SUPERFAMILY SSF53067 2 312 8.48E-68 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 Gene3D G3DSA:3.30.420.40 1 134 7.3E-47 T 16-09-2016 Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 ProSitePatterns PS01125 ROK family signature. 130 157 - T 16-09-2016 IPR000600 ROK family Spa2297_RS08740 68f56810e61026191f849949aaae9ab5 317 Pfam PF00480 ROK family 4 312 7.8E-110 T 16-09-2016 IPR000600 ROK family Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 PANTHER PTHR24362 11 409 1.6E-63 T 16-09-2016 Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 Pfam PF00069 Protein kinase domain 67 229 4.7E-17 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 SMART SM00220 18 270 3.9E-11 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 SUPERFAMILY SSF56112 11 260 1.66E-32 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 Gene3D G3DSA:1.10.510.10 81 259 3.8E-26 T 16-09-2016 Spa2297_RS02230 bc69dbfb772a05449ffd85e3104bbb94 531 PANTHER PTHR24362:SF282 11 409 1.6E-63 T 16-09-2016 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 Gene3D G3DSA:3.40.50.10490 12 258 3.1E-82 T 16-09-2016 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 13 306 41.556 T 16-09-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 17 306 1.1E-108 T 16-09-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 Pfam PF01380 SIS domain 140 219 2.4E-9 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 196 213 - T 16-09-2016 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 SUPERFAMILY SSF53697 18 258 8.49E-64 T 16-09-2016 Spa2297_RS14750 016562d67e2be5e2bc18187cec704404 311 PANTHER PTHR10088 1 306 8.0E-134 T 16-09-2016 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 Gene3D G3DSA:3.30.70.20 1 63 2.9E-18 T 16-09-2016 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 Pfam PF13459 4Fe-4S single cluster domain 4 61 3.2E-15 T 16-09-2016 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 PANTHER PTHR36923:SF1 1 63 8.9E-29 T 16-09-2016 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.7E-9 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.7E-9 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.7E-9 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 SUPERFAMILY SSF54862 2 62 1.03E-13 T 16-09-2016 Spa2297_RS29870 4d29ac70ab2074bca22e5681dc59d6a9 66 PANTHER PTHR36923 1 63 8.9E-29 T 16-09-2016 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.2E-78 T 16-09-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PRINTS PR00094 Adenylate kinase signature 161 176 5.1E-37 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PRINTS PR00094 Adenylate kinase signature 178 192 5.1E-37 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PRINTS PR00094 Adenylate kinase signature 81 97 5.1E-37 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PRINTS PR00094 Adenylate kinase signature 4 17 5.1E-37 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PRINTS PR00094 Adenylate kinase signature 32 46 5.1E-37 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 Pfam PF05191 Adenylate kinase, active site lid 127 163 1.2E-13 T 16-09-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 Gene3D G3DSA:3.40.50.300 1 211 2.2E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 Pfam PF00406 Adenylate kinase 5 191 2.6E-61 T 16-09-2016 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 Hamap MF_00235 Adenylate kinase [adk]. 1 214 52.662 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 SUPERFAMILY SSF52540 1 215 6.43E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19900 5aa2405f459625a356cf6aa1962c8896 217 PANTHER PTHR23359 1 213 4.2E-103 T 16-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PANTHER PTHR19139 7 125 3.5E-86 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 195 217 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 5 24 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 83 102 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 162 180 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 242 262 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PRINTS PR00783 Major intrinsic protein family signature 47 71 3.9E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 Pfam PF00230 Major intrinsic protein 6 259 8.5E-43 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PANTHER PTHR19139:SF147 143 263 3.5E-86 T 16-09-2016 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PANTHER PTHR19139:SF147 7 125 3.5E-86 T 16-09-2016 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 ProSitePatterns PS00221 MIP family signature. 65 73 - T 16-09-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 PANTHER PTHR19139 143 263 3.5E-86 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 SUPERFAMILY SSF81338 7 263 3.14E-59 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS06445 cc653a4b2572b4f8ad1388cdecd34ff1 264 Gene3D G3DSA:1.20.1080.10 6 263 4.1E-78 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 Pfam PF01965 DJ-1/PfpI family 41 184 8.3E-11 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 SUPERFAMILY SSF52317 9 205 1.76E-41 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 PANTHER PTHR11019 10 330 1.5E-108 T 16-09-2016 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 SMART SM00342 239 322 5.3E-24 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 Gene3D G3DSA:1.10.10.60 278 326 3.4E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 Gene3D G3DSA:1.10.10.60 223 277 4.3E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 PANTHER PTHR11019:SF68 10 330 1.5E-108 T 16-09-2016 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 SUPERFAMILY SSF46689 228 273 1.72E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 Pfam PF12833 Helix-turn-helix domain 246 323 9.3E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 Gene3D G3DSA:3.40.50.880 11 222 1.5E-43 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS14380 b8e68ecb302724cc15db549fcb995d44 335 SUPERFAMILY SSF46689 276 326 1.25E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 PANTHER PTHR32114:SF2 2 997 6.5E-113 T 16-09-2016 Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 Pfam PF13558 Putative exonuclease SbcCD, C subunit 889 954 2.4E-13 T 16-09-2016 Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 PANTHER PTHR32114 2 997 6.5E-113 T 16-09-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 Pfam PF13476 AAA domain 5 188 7.6E-25 T 16-09-2016 Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 Gene3D G3DSA:3.40.50.300 640 656 2.5E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 Gene3D G3DSA:3.40.50.300 2 182 2.5E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 Gene3D G3DSA:3.40.50.300 854 991 2.5E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 SUPERFAMILY SSF52540 3 189 4.5E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 SUPERFAMILY SSF52540 284 320 4.5E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 SUPERFAMILY SSF52540 843 985 4.5E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04765 fa950cde7cff47496666b7ccd5fea88e 997 SUPERFAMILY SSF52540 600 656 4.5E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18115 193c98d3d924f99e662dcd9d0e15f133 216 PANTHER PTHR33169 1 191 4.9E-102 T 16-09-2016 Spa2297_RS18115 193c98d3d924f99e662dcd9d0e15f133 216 PANTHER PTHR33169:SF5 1 191 4.9E-102 T 16-09-2016 Spa2297_RS18115 193c98d3d924f99e662dcd9d0e15f133 216 Gene3D G3DSA:1.10.10.10 4 96 3.9E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18115 193c98d3d924f99e662dcd9d0e15f133 216 SUPERFAMILY SSF46785 4 178 4.38E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18115 193c98d3d924f99e662dcd9d0e15f133 216 Pfam PF03551 Transcriptional regulator PadR-like family 8 83 1.4E-10 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS17475 9d0952d93dbc758ebc52804b00829c1c 385 PANTHER PTHR22926 5 336 8.0E-48 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS17475 9d0952d93dbc758ebc52804b00829c1c 385 PANTHER PTHR22926:SF3 5 336 8.0E-48 T 16-09-2016 Spa2297_RS17475 9d0952d93dbc758ebc52804b00829c1c 385 Pfam PF00953 Glycosyl transferase family 4 74 211 2.5E-12 T 16-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 PANTHER PTHR30146:SF4 4 341 3.2E-121 T 16-09-2016 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 Gene3D G3DSA:1.10.260.40 6 56 1.0E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 Gene3D G3DSA:3.40.50.2300 57 175 1.2E-43 T 16-09-2016 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 50 4.6E-16 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 SUPERFAMILY SSF53822 64 337 3.08E-72 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 SUPERFAMILY SSF47413 5 62 2.16E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 PANTHER PTHR30146 4 341 3.2E-121 T 16-09-2016 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 Pfam PF13377 Periplasmic binding protein-like domain 171 337 3.7E-38 T 16-09-2016 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 SMART SM00354 4 74 3.8E-23 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS29680 1432e39aa8c874767fa640bddb6a380e 341 Gene3D G3DSA:3.40.50.2300 176 309 1.4E-47 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 PANTHER PTHR33303 1 130 5.4E-178 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 SUPERFAMILY SSF52210 545 691 6.67E-28 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 PANTHER PTHR33303 244 688 5.4E-178 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 PANTHER PTHR33303:SF3 1 130 5.4E-178 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 PANTHER PTHR33303:SF3 244 688 5.4E-178 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Gene3D G3DSA:3.40.50.261 543 688 6.3E-11 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 402 539 5.3E-50 T 16-09-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 SUPERFAMILY SSF52210 382 539 1.83E-38 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Gene3D G3DSA:3.30.470.20 31 143 1.4E-4 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 SMART SM00881 258 353 6.6E-33 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Gene3D G3DSA:3.40.50.720 254 381 7.5E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Pfam PF13380 CoA binding domain 263 380 1.7E-22 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Pfam PF13549 ATP-grasp domain 16 235 5.6E-74 T 16-09-2016 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 Gene3D G3DSA:3.40.50.261 382 538 2.2E-30 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 SUPERFAMILY SSF51735 254 390 6.57E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27420 981517ea8e97e0c2826555368b0ad254 731 SUPERFAMILY SSF56059 28 239 3.31E-40 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Pfam PF00501 AMP-binding enzyme 24 477 4.8E-95 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Gene3D G3DSA:2.30.38.10 408 468 1.9E-22 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Gene3D G3DSA:3.40.50.980 19 189 4.4E-33 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 SUPERFAMILY SSF56801 348 606 6.93E-114 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 SUPERFAMILY SSF56801 18 294 6.93E-114 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 PANTHER PTHR24096 7 606 3.7E-214 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 PANTHER PTHR24096:SF193 7 606 3.7E-214 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Gene3D G3DSA:3.40.50.980 190 289 6.3E-28 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Gene3D G3DSA:3.40.50.980 345 407 6.3E-28 T 16-09-2016 Spa2297_RS27270 037dd7b201e2bf03163db4a5ddb4671b 608 Gene3D G3DSA:3.30.300.30 475 596 1.5E-4 T 16-09-2016 Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 PANTHER PTHR24220 12 229 1.1E-100 T 16-09-2016 Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 PANTHER PTHR24220:SF86 12 229 1.1E-100 T 16-09-2016 Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 Pfam PF00005 ABC transporter 30 178 2.0E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 SMART SM00382 39 227 1.6E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 Gene3D G3DSA:3.40.50.300 8 230 1.1E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24870 a819285f55367b89a700ea8ac425f2cf 231 SUPERFAMILY SSF52540 10 230 3.82E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12180 2bfe3794bc3f2a8c2a95ae45eb66447b 231 Gene3D G3DSA:3.40.50.1000 54 226 1.2E-28 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12180 2bfe3794bc3f2a8c2a95ae45eb66447b 231 SUPERFAMILY SSF56784 4 227 3.4E-36 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12180 2bfe3794bc3f2a8c2a95ae45eb66447b 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 46 192 1.7E-11 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12180 2bfe3794bc3f2a8c2a95ae45eb66447b 231 PANTHER PTHR18901 1 229 2.6E-24 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 Pfam PF13416 Bacterial extracellular solute-binding protein 61 368 3.2E-32 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 Gene3D G3DSA:3.40.190.10 174 355 2.0E-17 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 Gene3D G3DSA:3.40.190.10 61 173 7.5E-8 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 PANTHER PTHR30061:SF28 5 435 1.0E-256 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 SUPERFAMILY SSF53850 42 433 5.69E-48 T 16-09-2016 Spa2297_RS01065 ef5e675353a97c1acf30ea32f2be24b1 436 PANTHER PTHR30061 5 435 1.0E-256 T 16-09-2016 Spa2297_RS07680 3233e2c0f0207684c3a5a3bba31d5b25 221 Pfam PF10935 Protein of unknown function (DUF2637) 9 118 4.1E-19 T 16-09-2016 IPR021235 Protein of unknown function DUF2637 Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 SUPERFAMILY SSF52540 5 242 7.66E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 SUPERFAMILY SSF50331 237 333 8.99E-12 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 Pfam PF08402 TOBE domain 287 337 1.7E-5 T 16-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 PANTHER PTHR24220 6 249 3.9E-174 T 16-09-2016 Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 Gene3D G3DSA:3.40.50.300 5 238 7.0E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 SMART SM00382 30 220 6.6E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 PANTHER PTHR24220:SF487 6 249 3.9E-174 T 16-09-2016 Spa2297_RS06700 bf44c7b6c26f0fac58f40bdc2b460e45 445 Pfam PF00005 ABC transporter 22 162 1.6E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 PANTHER PTHR30061 1 417 1.5E-117 T 16-09-2016 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 SUPERFAMILY SSF53850 33 409 7.85E-66 T 16-09-2016 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 Gene3D G3DSA:3.40.190.10 159 353 9.5E-39 T 16-09-2016 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 Pfam PF01547 Bacterial extracellular solute-binding protein 48 336 1.2E-44 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 Gene3D G3DSA:3.40.190.10 38 158 2.0E-17 T 16-09-2016 Spa2297_RS30955 1be2da6f952559f4e163d84320c3dbeb 421 PANTHER PTHR30061:SF24 1 417 1.5E-117 T 16-09-2016 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 SMART SM00530 29 84 4.7E-4 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 PANTHER PTHR10245:SF7 3 280 4.4E-38 T 16-09-2016 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 SUPERFAMILY SSF47413 23 77 8.0E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 Pfam PF13560 Helix-turn-helix domain 27 80 2.7E-9 T 16-09-2016 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 PANTHER PTHR10245 3 280 4.4E-38 T 16-09-2016 Spa2297_RS19730 cb71d0f3e5848e0c8c5dc5241fd756dd 282 Gene3D G3DSA:1.10.260.40 25 77 2.0E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 SUPERFAMILY SSF52317 3 231 5.09E-55 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 PANTHER PTHR11019:SF97 25 68 2.8E-23 T 16-09-2016 Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 PANTHER PTHR11019:SF97 91 229 2.8E-23 T 16-09-2016 Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 PANTHER PTHR11019 25 68 2.8E-23 T 16-09-2016 Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 PANTHER PTHR11019 91 229 2.8E-23 T 16-09-2016 Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 Pfam PF17124 ThiJ/PfpI family-like 25 114 5.7E-12 T 16-09-2016 IPR032633 ThiJ/PfpI family-like Spa2297_RS25525 9b000e94e91f4ae194390f45b160fc10 232 Gene3D G3DSA:3.40.50.880 2 231 9.9E-76 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PIRSF PIRSF000188 12 363 2.7E-141 T 16-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 207 1.4E-19 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 77 91 1.4E-19 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 143 165 1.4E-19 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 300 311 1.4E-19 T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 33 142 9.3E-25 T 16-09-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 309 2.5E-8 T 16-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 Gene3D G3DSA:3.40.192.10 17 158 6.3E-64 T 16-09-2016 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 Gene3D G3DSA:3.40.50.720 159 350 3.6E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 SUPERFAMILY SSF51735 152 360 3.62E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 SUPERFAMILY SSF53223 22 155 5.12E-44 T 16-09-2016 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 85 98 - T 16-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 SMART SM00839 155 363 2.2E-40 T 16-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PANTHER PTHR11606:SF3 36 361 9.6E-144 T 16-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 Spa2297_RS15750 346e971d11aaaf25fb5788d7fd4cd988 364 PANTHER PTHR11606 36 361 9.6E-144 T 16-09-2016 Spa2297_RS16410 0edb091ff0dd5c435d59f2a198e74f5d 461 SUPERFAMILY SSF56601 17 324 3.81E-71 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16410 0edb091ff0dd5c435d59f2a198e74f5d 461 Gene3D G3DSA:3.40.710.10 25 339 7.8E-73 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16410 0edb091ff0dd5c435d59f2a198e74f5d 461 Pfam PF00144 Beta-lactamase 23 331 6.1E-63 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS16410 0edb091ff0dd5c435d59f2a198e74f5d 461 PANTHER PTHR22935 19 377 5.2E-66 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 Gene3D G3DSA:3.40.50.1820 215 341 1.3E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 Gene3D G3DSA:3.40.50.1820 397 517 1.3E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 Gene3D G3DSA:3.40.50.1820 83 171 1.3E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992 46 170 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992 217 306 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992 404 519 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992:SF878 217 306 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992:SF878 46 170 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 PANTHER PTHR10992:SF878 404 519 1.2E-75 T 16-09-2016 Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 Pfam PF08386 TAP-like protein 431 529 2.7E-28 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 SUPERFAMILY SSF53474 217 271 4.47E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 SUPERFAMILY SSF53474 101 172 4.47E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04455 540ba7a861b59664d919c462b835200d 537 SUPERFAMILY SSF53474 350 517 4.47E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS24050 b8ea73744a2c75641620d4b726b552f6 244 Pfam PF13374 Tetratricopeptide repeat 196 228 0.017 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS24050 b8ea73744a2c75641620d4b726b552f6 244 SUPERFAMILY SSF48452 119 228 8.93E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS24050 b8ea73744a2c75641620d4b726b552f6 244 Gene3D G3DSA:1.25.40.10 89 227 9.7E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11405 f4a2692f55d0fc2904923738159aa540 201 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 120 191 6.1E-22 T 16-09-2016 IPR018656 Domain of unknown function DUF2087 Spa2297_RS07585 a11ce92377711228b6f8767c2e09f58c 291 Gene3D G3DSA:1.10.3720.10 17 277 8.9E-45 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07585 a11ce92377711228b6f8767c2e09f58c 291 PANTHER PTHR32243 13 291 2.4E-132 T 16-09-2016 Spa2297_RS07585 a11ce92377711228b6f8767c2e09f58c 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 271 7.5E-13 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07585 a11ce92377711228b6f8767c2e09f58c 291 PANTHER PTHR32243:SF11 13 291 2.4E-132 T 16-09-2016 Spa2297_RS07585 a11ce92377711228b6f8767c2e09f58c 291 SUPERFAMILY SSF161098 18 291 9.03E-52 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23485 75b78b715a61cd048daee291d5241cd7 137 Gene3D G3DSA:3.30.450.30 3 123 1.7E-25 T 16-09-2016 Spa2297_RS23485 75b78b715a61cd048daee291d5241cd7 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.1E-26 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS23485 75b78b715a61cd048daee291d5241cd7 137 SMART SM00960 9 99 1.1E-32 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS23485 75b78b715a61cd048daee291d5241cd7 137 SUPERFAMILY SSF103196 2 125 3.14E-32 T 16-09-2016 Spa2297_RS23485 75b78b715a61cd048daee291d5241cd7 137 PANTHER PTHR36222 1 137 1.1E-55 T 16-09-2016 Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 SUPERFAMILY SSF50939 53 402 5.33E-81 T 16-09-2016 IPR011040 Sialidases Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 SMART SM00282 461 595 6.0E-13 T 16-09-2016 IPR001791 Laminin G domain Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 SMART SM00560 461 600 4.2E-33 T 16-09-2016 IPR006558 LamG-like jellyroll fold Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 PANTHER PTHR10628:SF5 43 539 4.5E-127 T 16-09-2016 Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 SUPERFAMILY SSF49899 397 604 9.13E-34 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 442 603 1.7E-21 T 16-09-2016 Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 Pfam PF13088 BNR repeat-like domain 72 376 4.5E-31 T 16-09-2016 IPR011040 Sialidases Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 PANTHER PTHR10628 43 539 4.5E-127 T 16-09-2016 IPR026856 Sialidase family GO:0004308 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 Gene3D G3DSA:2.120.10.10 55 400 4.5E-80 T 16-09-2016 IPR011040 Sialidases Spa2297_RS27295 14bd3934cdafd275d989b3c874eb44e3 627 Gene3D G3DSA:2.60.120.200 401 603 1.2E-25 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 Gene3D G3DSA:1.10.630.10 28 482 1.8E-112 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 SUPERFAMILY SSF48264 28 482 2.23E-104 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 424 433 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 Pfam PF00067 Cytochrome P450 31 461 5.7E-78 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00463 E-class P450 group I signature 301 327 6.6E-20 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00463 E-class P450 group I signature 421 431 6.6E-20 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00463 E-class P450 group I signature 431 454 6.6E-20 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00463 E-class P450 group I signature 281 298 6.6E-20 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00463 E-class P450 group I signature 59 78 6.6E-20 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PANTHER PTHR24305:SF21 24 483 7.9E-154 T 16-09-2016 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00385 P450 superfamily signature 345 356 3.2E-11 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00385 P450 superfamily signature 292 309 3.2E-11 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00385 P450 superfamily signature 422 431 3.2E-11 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PRINTS PR00385 P450 superfamily signature 431 442 3.2E-11 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29705 906524569535fec2af6d2f816ce5fc68 518 PANTHER PTHR24305 24 483 7.9E-154 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 Gene3D G3DSA:3.40.50.720 6 230 9.9E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366:SF340 8 178 5.5E-99 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366 195 269 5.5E-99 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 Gene3D G3DSA:3.90.25.10 231 322 2.0E-6 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 SUPERFAMILY SSF51735 7 324 8.06E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366:SF340 195 269 5.5E-99 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366 8 178 5.5E-99 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 180 4.7E-19 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366 286 340 5.5E-99 T 16-09-2016 Spa2297_RS29750 6c027ea349047052847459d290c109f8 343 PANTHER PTHR10366:SF340 286 340 5.5E-99 T 16-09-2016 Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 Pfam PF07730 Histidine kinase 153 217 7.1E-17 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 PANTHER PTHR24421:SF10 121 356 4.2E-57 T 16-09-2016 Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 Gene3D G3DSA:3.30.565.10 238 344 6.6E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 SUPERFAMILY SSF55874 224 341 6.17E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 PANTHER PTHR24421 121 356 4.2E-57 T 16-09-2016 Spa2297_RS24480 dcbd0e346fa80eda3dd416d1541ab761 356 SMART SM00304 88 140 2.4E-5 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 SUPERFAMILY SSF53448 8 282 5.42E-64 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 SUPERFAMILY SSF53448 343 360 5.42E-64 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 SUPERFAMILY SSF51161 312 386 6.1E-15 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 PANTHER PTHR22572 9 379 6.7E-148 T 16-09-2016 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 8 379 3.0E-131 T 16-09-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 PANTHER PTHR22572:SF10 9 379 6.7E-148 T 16-09-2016 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 Gene3D G3DSA:3.90.550.10 10 289 2.7E-65 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 Gene3D G3DSA:3.90.550.10 326 369 2.7E-65 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 5 405 47.475 T 16-09-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 14 33 - T 16-09-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 Pfam PF00483 Nucleotidyl transferase 10 278 3.7E-66 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 16-09-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS28850 bff6d77bbdbe772c737eb45172c4149f 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 198 208 - T 16-09-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 Spa2297_RS21285 3a201575d79d0950ff98f686edcb9555 239 SUPERFAMILY SSF53955 166 234 1.64E-11 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS21285 3a201575d79d0950ff98f686edcb9555 239 Gene3D G3DSA:1.10.530.10 164 232 8.8E-8 T 16-09-2016 Spa2297_RS21285 3a201575d79d0950ff98f686edcb9555 239 Pfam PF01464 Transglycosylase SLT domain 162 227 4.1E-7 T 16-09-2016 IPR008258 Transglycosylase SLT domain 1 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 PANTHER PTHR10668:SF74 1 539 6.2E-254 T 16-09-2016 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 PANTHER PTHR10668 1 539 6.2E-254 T 16-09-2016 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 43 2.5E-7 T 16-09-2016 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 SUPERFAMILY SSF51905 1 326 2.09E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 SUPERFAMILY SSF51905 473 513 2.09E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 Gene3D G3DSA:3.50.50.60 458 518 9.3E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 Gene3D G3DSA:3.50.50.60 220 290 9.3E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01755 c82b08d671b32a941ab37017e73bf4c3 539 Gene3D G3DSA:3.50.50.60 2 53 9.3E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 16-09-2016 IPR019844 Cold-shock conserved site Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 PANTHER PTHR11544 1 65 1.4E-42 T 16-09-2016 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 SUPERFAMILY SSF50249 1 64 8.04E-25 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 SMART SM00357 3 66 1.1E-30 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 Gene3D G3DSA:2.40.50.140 1 65 1.2E-32 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.1E-31 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS14810 6d23802b0a38ece9f2819d86e25475a5 67 PIRSF PIRSF002599 1 67 6.7E-26 T 16-09-2016 IPR012156 Cold shock, CspA GO:0003676 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 PANTHER PTHR34216 23 505 6.4E-176 T 16-09-2016 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 SUPERFAMILY SSF88713 229 258 7.23E-21 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 SUPERFAMILY SSF88713 84 201 7.23E-21 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 Gene3D G3DSA:3.20.20.370 96 257 1.8E-13 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 Pfam PF01522 Polysaccharide deacetylase 121 263 3.5E-21 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS21395 9c3edf6ced219c885de668506791951e 505 PANTHER PTHR34216:SF3 23 505 6.4E-176 T 16-09-2016 Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 Pfam PF00266 Aminotransferase class-V 18 346 2.2E-18 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 Gene3D G3DSA:3.90.1150.10 262 351 1.7E-5 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 Gene3D G3DSA:3.40.640.10 49 261 3.3E-29 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 PANTHER PTHR11601 14 350 8.6E-85 T 16-09-2016 Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 PANTHER PTHR11601:SF31 14 350 8.6E-85 T 16-09-2016 Spa2297_RS07455 61eeed96d05a971801629b954329dd0f 352 SUPERFAMILY SSF53383 13 351 1.12E-49 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 PRINTS PR01483 Fatty acid synthase signature 55 76 2.5E-7 T 16-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 PRINTS PR01483 Fatty acid synthase signature 33 55 2.5E-7 T 16-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 PANTHER PTHR13078 6 110 4.3E-22 T 16-09-2016 Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 Gene3D G3DSA:3.10.129.10 17 149 2.1E-38 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 SUPERFAMILY SSF54637 13 147 2.67E-29 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS19570 91dca37c8248e5030b5073bde3bdc1e7 150 Pfam PF01575 MaoC like domain 24 128 5.7E-25 T 16-09-2016 IPR002539 MaoC-like domain Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 Pfam PF13416 Bacterial extracellular solute-binding protein 62 385 2.4E-35 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 Gene3D G3DSA:3.40.190.10 159 339 1.2E-35 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 PANTHER PTHR30061:SF1 7 443 1.8E-83 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 PANTHER PTHR30061 7 443 1.8E-83 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 SUPERFAMILY SSF53850 23 441 2.45E-67 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 Gene3D G3DSA:3.40.190.10 340 363 1.2E-21 T 16-09-2016 Spa2297_RS11255 5e326e51c3d79bf0dcbbf1c194ef1c49 445 Gene3D G3DSA:3.40.190.10 8 153 1.2E-21 T 16-09-2016 Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 11 108 1.5E-23 T 16-09-2016 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 Gene3D G3DSA:3.30.750.24 157 249 3.8E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 PANTHER PTHR33745 129 278 1.9E-55 T 16-09-2016 Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 Pfam PF01740 STAS domain 163 261 3.4E-9 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 SUPERFAMILY SSF52091 156 265 1.73E-17 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29200 d37696a0ed092c4aa6b5412d18c20123 282 PANTHER PTHR33745:SF1 129 278 1.9E-55 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 SUPERFAMILY SSF103473 14 203 3.66E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 SUPERFAMILY SSF103473 458 481 3.66E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 SUPERFAMILY SSF103473 255 429 3.66E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 Gene3D G3DSA:1.20.1250.20 16 198 1.7E-30 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 PANTHER PTHR23501 12 504 5.4E-218 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 Gene3D G3DSA:1.20.1250.20 276 482 2.7E-13 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 Pfam PF07690 Major Facilitator Superfamily 23 418 1.1E-51 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 PANTHER PTHR23501:SF69 12 504 5.4E-218 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 454 2.5E-76 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 3.1E-6 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 3.1E-6 T 16-09-2016 Spa2297_RS13960 3381b5a6b1227ce1c120df5a52f82e70 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 210 228 3.1E-6 T 16-09-2016 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 308 7.0E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 Gene3D G3DSA:1.10.3720.10 27 309 6.9E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 SUPERFAMILY SSF160964 33 67 3.01E-5 T 16-09-2016 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 PANTHER PTHR30193 7 322 1.6E-135 T 16-09-2016 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 SUPERFAMILY SSF161098 77 306 2.62E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31445 b3231fd243d84e6c1a07422e4aaef5df 323 PANTHER PTHR30193:SF1 7 322 1.6E-135 T 16-09-2016 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070:SF25 351 437 1.2E-244 T 16-09-2016 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 SUPERFAMILY SSF52540 184 263 4.45E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 SUPERFAMILY SSF52540 343 418 4.45E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 SUPERFAMILY SSF52540 528 746 4.45E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070 457 744 1.2E-244 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070 88 272 1.2E-244 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 Gene3D G3DSA:3.40.50.300 185 293 8.3E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 Gene3D G3DSA:3.40.50.300 511 610 8.3E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 Gene3D G3DSA:3.40.50.300 611 749 1.9E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 Pfam PF13245 Part of AAA domain 198 263 2.9E-16 T 16-09-2016 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070:SF25 457 744 1.2E-244 T 16-09-2016 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070:SF25 88 272 1.2E-244 T 16-09-2016 Spa2297_RS22995 6d9cfc3a8fff1d3e881b97d4eff0a625 756 PANTHER PTHR11070 351 437 1.2E-244 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 334 355 - T 16-09-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 20 417 5.3E-153 T 16-09-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 Gene3D G3DSA:3.40.605.10 386 427 2.7E-104 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 Gene3D G3DSA:3.40.605.10 8 231 2.7E-104 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 SUPERFAMILY SSF53720 10 427 1.57E-115 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 PANTHER PTHR11063:SF8 8 428 2.4E-182 T 16-09-2016 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 PANTHER PTHR11063 8 428 2.4E-182 T 16-09-2016 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 427 41.98 T 16-09-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 PIRSF PIRSF000151 6 428 9.8E-174 T 16-09-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 Gene3D G3DSA:3.40.309.10 234 385 1.5E-40 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS10915 db254a3c8d1802974a777e2067d38ed9 428 Pfam PF00171 Aldehyde dehydrogenase family 12 299 1.5E-22 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 1.0E-25 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.0E-25 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 1.0E-25 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 1.0E-25 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 41.277 T 16-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 2.1E-184 T 16-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 16-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Gene3D G3DSA:1.10.40.30 383 439 1.9E-27 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PANTHER PTHR11444 9 464 3.1E-211 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Pfam PF00206 Lyase 21 309 4.6E-64 T 16-09-2016 IPR022761 Fumarate lyase, N-terminal Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Gene3D G3DSA:1.10.275.10 9 114 2.3E-35 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.6E-54 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 SUPERFAMILY SSF48557 13 462 6.28E-139 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Gene3D G3DSA:1.20.200.10 115 382 2.0E-98 T 16-09-2016 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 PANTHER PTHR11444:SF3 9 464 3.1E-211 T 16-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06030 d1aee3cc777b1e7bbd7b07609a87f48b 475 Pfam PF14698 Argininosuccinate lyase C-terminal 372 438 4.4E-22 T 16-09-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Gene3D G3DSA:1.10.1040.10 192 288 8.9E-27 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Gene3D G3DSA:1.10.1040.10 420 498 3.4E-14 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 212 - T 16-09-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 PANTHER PTHR23309:SF12 7 306 1.4E-220 T 16-09-2016 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 PANTHER PTHR23309:SF12 407 500 1.4E-220 T 16-09-2016 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 187 2.4E-57 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 3.5E-28 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 420 499 1.1E-13 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 PANTHER PTHR23309 7 306 1.4E-220 T 16-09-2016 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 PANTHER PTHR23309 407 500 1.4E-220 T 16-09-2016 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 SUPERFAMILY SSF51735 8 189 5.92E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 SUPERFAMILY SSF48179 420 500 4.76E-13 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 Gene3D G3DSA:3.40.50.720 9 191 2.8E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16795 84cfb8e855d84a8b716b1a90e2d7307c 511 SUPERFAMILY SSF48179 189 299 1.36E-26 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS13120 058ba972ae568abf6d98c1e2556f5fed 126 Pfam PF06262 Zinicin-like metallopeptidase 60 121 7.7E-7 T 16-09-2016 IPR010428 Zinicin-like metallopeptidase Spa2297_RS13120 058ba972ae568abf6d98c1e2556f5fed 126 SUPERFAMILY SSF55486 14 123 9.16E-24 T 16-09-2016 Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 Pfam PF03193 Protein of unknown function, DUF258 95 272 8.6E-41 T 16-09-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 335 26.447 T 16-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 SUPERFAMILY SSF52540 113 333 3.35E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 Gene3D G3DSA:1.10.40.50 274 334 1.5E-12 T 16-09-2016 Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 Gene3D G3DSA:3.40.50.300 113 272 1.6E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 326 5.3E-39 T 16-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 Spa2297_RS22035 67d01795faf3f6cf39d8fc3eab1e4e80 337 PANTHER PTHR32120 9 335 4.1E-68 T 16-09-2016 Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 PANTHER PTHR11764:SF12 35 663 0.0 T 16-09-2016 Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 SUPERFAMILY SSF48239 325 655 5.1E-105 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 Gene3D G3DSA:1.50.10.20 323 653 1.7E-114 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 42 328 4.3E-122 T 16-09-2016 IPR032697 Squalene cyclase, N-terminal Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 41 653 2.7E-185 T 16-09-2016 IPR018333 Squalene cyclase GO:0016866 Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 PANTHER PTHR11764 35 663 0.0 T 16-09-2016 Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 SUPERFAMILY SSF48239 66 332 3.06E-74 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 Gene3D G3DSA:1.50.10.20 64 322 1.3E-67 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 ProSitePatterns PS01074 Terpene synthases signature. 510 524 - T 16-09-2016 IPR002365 Terpene synthase, conserved site GO:0016866 Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 338 654 6.0E-138 T 16-09-2016 IPR032696 Squalene cyclase, C-terminal Spa2297_RS28175 ad1ae2d4e6ee40a1a81f63d7dd83c3dd 684 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 36 655 2.9E-240 T 16-09-2016 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072|UniPathway: UPA00337 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 SUPERFAMILY SSF88659 125 180 1.23E-9 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 Gene3D G3DSA:1.10.1740.10 7 113 3.4E-27 T 16-09-2016 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 PANTHER PTHR30173 1 183 6.9E-75 T 16-09-2016 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 SUPERFAMILY SSF88946 4 105 1.96E-26 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 PANTHER PTHR30173:SF3 1 183 6.9E-75 T 16-09-2016 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 Gene3D G3DSA:1.10.10.10 127 180 1.8E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 Pfam PF08281 Sigma-70, region 4 127 176 6.7E-11 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 179 3.3E-20 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20560 4fa927ab38ff72282a04a902313cbbc7 220 Pfam PF04542 Sigma-70 region 2 27 93 2.1E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 116 135 4.6E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 412 425 4.6E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 334 348 4.6E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 349 363 4.6E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 277 299 4.6E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 Gene3D G3DSA:3.40.710.10 90 145 1.5E-8 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PANTHER PTHR30023:SF0 38 444 9.5E-76 T 16-09-2016 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 84 211 3.9E-24 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 240 448 1.5E-50 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 Gene3D G3DSA:3.40.710.10 243 458 6.3E-58 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 242 433 5.7E-42 T 16-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 PANTHER PTHR30023 38 444 9.5E-76 T 16-09-2016 Spa2297_RS18160 8dea4057b9933d53e236aeb849f04ec9 459 SUPERFAMILY SSF56601 83 456 7.61E-60 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 SUPERFAMILY SSF103481 187 287 1.26E-11 T 16-09-2016 Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 Pfam PF00892 EamA-like transporter family 4 136 5.5E-13 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 Pfam PF00892 EamA-like transporter family 150 283 8.5E-10 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 PANTHER PTHR32322:SF10 2 286 7.4E-152 T 16-09-2016 Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 PANTHER PTHR32322 2 286 7.4E-152 T 16-09-2016 Spa2297_RS23420 0d1dc7e837c523b83cd6e652135650f0 310 SUPERFAMILY SSF103481 39 138 4.05E-10 T 16-09-2016 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 PANTHER PTHR26402 2 197 1.8E-39 T 16-09-2016 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 2.6E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 2.6E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 2.6E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 PANTHER PTHR26402:SF137 2 197 1.8E-39 T 16-09-2016 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 SUPERFAMILY SSF46894 126 197 8.16E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 191 1.5E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 Gene3D G3DSA:1.10.10.10 143 197 1.0E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 SMART SM00421 135 192 1.7E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 SUPERFAMILY SSF52172 1 126 4.98E-8 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS27815 8c14781c9f5fa33ae55810f884174299 198 Gene3D G3DSA:3.40.50.2300 2 142 1.8E-9 T 16-09-2016 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 4.4E-52 T 16-09-2016 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Gene3D G3DSA:2.40.30.10 302 392 2.5E-31 T 16-09-2016 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 147 5.9E-12 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.4E-23 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.4E-23 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.4E-23 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.4E-23 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.4E-23 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 SUPERFAMILY SSF50447 208 302 2.16E-26 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 392 1.2E-169 T 16-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 SUPERFAMILY SSF52540 8 229 8.01E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Gene3D G3DSA:3.40.50.300 8 214 2.2E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Pfam PF03143 Elongation factor Tu C-terminal domain 300 392 1.9E-22 T 16-09-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 393 52.059 T 16-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PANTHER PTHR23115:SF112 1 393 6.7E-203 T 16-09-2016 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Pfam PF03144 Elongation factor Tu domain 2 228 294 5.1E-14 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 PANTHER PTHR23115 1 393 6.7E-203 T 16-09-2016 Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 SUPERFAMILY SSF50465 304 391 4.32E-25 T 16-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Spa2297_RS04855 ebf15f24555854046a5a56ac00b1465a 393 Gene3D G3DSA:2.40.30.10 215 299 4.4E-30 T 16-09-2016 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 SUPERFAMILY SSF161098 17 260 2.22E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 59 262 3.1E-75 T 16-09-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 264 3.7E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 36 256 1.2E-74 T 16-09-2016 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 Gene3D G3DSA:1.10.3720.10 20 259 7.3E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS17215 886655f9af97df797718d9f9a60ca21a 269 PANTHER PTHR30183 1 266 1.7E-87 T 16-09-2016 Spa2297_RS02825 5c7ba7eb2edf1534c357432e9b7002ef 243 Gene3D G3DSA:3.30.450.40 82 215 5.7E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02825 5c7ba7eb2edf1534c357432e9b7002ef 243 Pfam PF01590 GAF domain 127 215 6.7E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS02825 5c7ba7eb2edf1534c357432e9b7002ef 243 Gene3D G3DSA:1.10.10.10 2 44 4.5E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02825 5c7ba7eb2edf1534c357432e9b7002ef 243 SUPERFAMILY SSF55781 82 220 7.85E-12 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02825 5c7ba7eb2edf1534c357432e9b7002ef 243 Pfam PF03861 ANTAR domain 1 43 1.1E-11 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS29690 f87cbf6967c1a5eb69ffa144ed7449d3 247 SUPERFAMILY SSF102588 16 245 2.22E-46 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS29690 f87cbf6967c1a5eb69ffa144ed7449d3 247 PANTHER PTHR12993:SF11 8 224 5.2E-49 T 16-09-2016 Spa2297_RS29690 f87cbf6967c1a5eb69ffa144ed7449d3 247 Gene3D G3DSA:3.40.50.10320 16 244 5.5E-53 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS29690 f87cbf6967c1a5eb69ffa144ed7449d3 247 PANTHER PTHR12993 8 224 5.2E-49 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS29690 f87cbf6967c1a5eb69ffa144ed7449d3 247 Pfam PF02585 GlcNAc-PI de-N-acetylase 20 148 2.1E-27 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 SUPERFAMILY SSF47384 256 338 4.71E-19 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 SMART SM00388 270 337 7.9E-23 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 381 489 2.0E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 SUPERFAMILY SSF55874 326 489 5.63E-41 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 4.9E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 4.9E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 445 4.9E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 431 4.9E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 Gene3D G3DSA:1.10.287.130 263 322 2.2E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 Pfam PF00672 HAMP domain 183 258 6.3E-12 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 Pfam PF00512 His Kinase A (phospho-acceptor) domain 272 337 6.3E-19 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 Gene3D G3DSA:3.30.565.10 323 489 3.3E-43 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 PANTHER PTHR24423 241 495 3.4E-84 T 16-09-2016 Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 SMART SM00387 380 491 1.3E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16050 4f5a00c44b774a2200793593ca06ad39 514 SMART SM00304 200 262 1.0E-7 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 PANTHER PTHR24220 1 197 1.4E-49 T 16-09-2016 Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 Gene3D G3DSA:3.40.50.300 2 191 2.1E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 SMART SM00382 1 176 1.5E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 Pfam PF00005 ABC transporter 2 128 1.5E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 ProSitePatterns PS00211 ABC transporters family signature. 101 115 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 SUPERFAMILY SSF52540 1 183 1.43E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28725 e40880d8ebbe069564f415395a422515 199 PANTHER PTHR24220:SF218 1 197 1.4E-49 T 16-09-2016 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 SUPERFAMILY SSF47413 1 53 5.81E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 Gene3D G3DSA:3.40.50.2300 52 162 2.4E-9 T 16-09-2016 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 PANTHER PTHR30146 1 337 2.9E-210 T 16-09-2016 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 SMART SM00354 1 65 4.5E-15 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 Pfam PF13377 Periplasmic binding protein-like domain 165 324 1.2E-28 T 16-09-2016 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 PANTHER PTHR30146:SF47 1 337 2.9E-210 T 16-09-2016 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 42 1.2E-11 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 Gene3D G3DSA:1.10.260.40 1 51 4.0E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 SUPERFAMILY SSF53822 74 329 2.36E-35 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS16310 dbcb84df316e5c56bb06071eac72fe01 342 Gene3D G3DSA:3.40.50.2300 163 325 8.0E-33 T 16-09-2016 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 11 354 2.3E-108 T 16-09-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 PANTHER PTHR23024:SF215 52 129 9.3E-38 T 16-09-2016 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 SUPERFAMILY SSF51905 8 249 5.99E-16 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 Gene3D G3DSA:3.50.50.60 214 359 5.7E-4 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 PANTHER PTHR23024 52 129 9.3E-38 T 16-09-2016 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 Gene3D G3DSA:3.50.50.60 97 213 5.7E-11 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 SUPERFAMILY SSF51905 305 384 4.63E-5 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08205 0ec4c65d231e08a886c5f12371345e19 468 SUPERFAMILY SSF51905 204 261 4.63E-5 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26385 ba58898e4d01695624b4c50514d95447 504 PANTHER PTHR34384 1 503 6.9E-153 T 16-09-2016 Spa2297_RS26385 ba58898e4d01695624b4c50514d95447 504 Pfam PF06276 Ferric iron reductase FhuF-like transporter 347 452 2.0E-12 T 16-09-2016 IPR022770 Ferric iron reductase FhuF domain Spa2297_RS26385 ba58898e4d01695624b4c50514d95447 504 PANTHER PTHR34384:SF6 1 503 6.9E-153 T 16-09-2016 Spa2297_RS26385 ba58898e4d01695624b4c50514d95447 504 Pfam PF04183 IucA / IucC family 152 338 3.6E-28 T 16-09-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 SUPERFAMILY SSF143548 17 159 1.88E-47 T 16-09-2016 IPR029009 Allosteric substrate binding domain Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 Gene3D G3DSA:3.30.1330.90 11 159 3.0E-57 T 16-09-2016 IPR029009 Allosteric substrate binding domain Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 PANTHER PTHR30182 3 452 1.1E-246 T 16-09-2016 Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 452 2.3E-211 T 16-09-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 Pfam PF03313 Serine dehydratase alpha chain 188 449 8.8E-106 T 16-09-2016 IPR005130 Serine dehydratase-like, alpha subunit Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 Pfam PF03315 Serine dehydratase beta chain 4 157 6.1E-61 T 16-09-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 Spa2297_RS23120 081db2184563accf75f05bf75c326df4 455 PANTHER PTHR30182:SF1 3 452 1.1E-246 T 16-09-2016 Spa2297_RS18675 9260f7f4ec7e8471b59474356c83364f 112 PANTHER PTHR36116 1 111 1.1E-49 T 16-09-2016 Spa2297_RS18675 9260f7f4ec7e8471b59474356c83364f 112 PANTHER PTHR36116:SF1 1 111 1.1E-49 T 16-09-2016 Spa2297_RS18675 9260f7f4ec7e8471b59474356c83364f 112 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 109 9.6E-42 T 16-09-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 Spa2297_RS18675 9260f7f4ec7e8471b59474356c83364f 112 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 20.792 T 16-09-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 Spa2297_RS18675 9260f7f4ec7e8471b59474356c83364f 112 SUPERFAMILY SSF103481 10 109 1.03E-10 T 16-09-2016 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 PANTHER PTHR30328 9 136 9.8E-35 T 16-09-2016 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 Gene3D G3DSA:1.10.357.10 24 251 1.3E-62 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 PANTHER PTHR30328:SF17 9 136 9.8E-35 T 16-09-2016 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 98 248 3.5E-15 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 SUPERFAMILY SSF48498 100 251 3.0E-29 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 5.1E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS16030 b5de9386a1b17b1aaadf95fc07852250 252 SUPERFAMILY SSF46689 30 96 2.14E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 328 705 3.2E-55 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PANTHER PTHR30620 537 825 2.3E-254 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Gene3D G3DSA:3.20.20.300 29 286 1.0E-88 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 SMART SM01217 741 811 1.6E-19 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PANTHER PTHR30620:SF18 537 825 2.3E-254 T 16-09-2016 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PANTHER PTHR30620:SF18 5 391 2.3E-254 T 16-09-2016 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PANTHER PTHR30620 5 391 2.3E-254 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 37 279 1.4E-53 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Gene3D G3DSA:3.40.50.1700 313 396 1.2E-65 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Gene3D G3DSA:3.40.50.1700 553 707 1.2E-65 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 143 159 1.5E-32 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 211 229 1.5E-32 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 37 53 1.5E-32 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 66 85 1.5E-32 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 112 128 1.5E-32 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 SUPERFAMILY SSF51445 5 297 3.68E-82 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 SUPERFAMILY SSF52279 553 708 7.32E-49 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 SUPERFAMILY SSF52279 328 396 7.32E-49 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS27515 5dd837a4b569754c74b0ecaa9845be5c 828 Pfam PF14310 Fibronectin type III-like domain 741 810 4.4E-17 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 Gene3D G3DSA:2.30.40.10 132 158 2.9E-8 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 Pfam PF01979 Amidohydrolase family 69 183 6.0E-14 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 Gene3D G3DSA:3.20.20.140 3 131 8.7E-10 T 16-09-2016 Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 Gene3D G3DSA:2.30.40.10 159 189 3.6E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 SUPERFAMILY SSF51338 110 184 3.12E-12 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS28250 073ce8e790c5fb6bfa90a9c5baaf48c7 203 SUPERFAMILY SSF51556 3 150 1.96E-9 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 3.4E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 3.4E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 3.4E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 Gene3D G3DSA:1.10.10.10 8 93 8.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 SMART SM00418 13 92 4.6E-15 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 Pfam PF12840 Helix-turn-helix domain 13 72 1.7E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 PANTHER PTHR39168:SF1 1 234 2.2E-66 T 16-09-2016 Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 SUPERFAMILY SSF46785 10 91 4.01E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06675 f63b9fec929b00f5b12e147bc0efd69e 237 PANTHER PTHR39168 1 234 2.2E-66 T 16-09-2016 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 Pfam PF13977 Bacterial transcriptional repressor 110 200 1.2E-7 T 16-09-2016 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 SUPERFAMILY SSF46689 9 90 9.71E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 SUPERFAMILY SSF48498 92 197 5.93E-10 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 PANTHER PTHR30328 8 200 1.4E-45 T 16-09-2016 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.0E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 Gene3D G3DSA:1.10.357.10 9 200 3.5E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02165 ea3130ebff12d9b1ec107f35930d5ef8 207 PANTHER PTHR30328:SF29 8 200 1.4E-45 T 16-09-2016 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 SUPERFAMILY SSF161098 84 339 3.92E-43 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 PANTHER PTHR30425 68 352 5.7E-114 T 16-09-2016 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 78 344 1.4E-86 T 16-09-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 350 1.1E-25 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 PANTHER PTHR30425:SF0 68 352 5.7E-114 T 16-09-2016 Spa2297_RS15475 04be9712d79a882258e469871e118bc3 352 Gene3D G3DSA:1.10.3720.10 76 346 1.9E-46 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 624 4.2E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 PANTHER PTHR24423:SF523 384 629 1.2E-82 T 16-09-2016 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 SMART SM00387 516 626 0.0015 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 Pfam PF00672 HAMP domain 316 400 8.1E-10 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 PANTHER PTHR24423:SF523 775 890 1.2E-82 T 16-09-2016 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 PANTHER PTHR24423 775 890 1.2E-82 T 16-09-2016 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 PANTHER PTHR24423 384 629 1.2E-82 T 16-09-2016 Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 Pfam PF08376 Nitrate and nitrite sensing 58 296 4.3E-35 T 16-09-2016 IPR013587 Nitrate/nitrite sensing protein Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 Gene3D G3DSA:3.30.565.10 482 624 1.1E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS05185 deb1f611c3d3d8a8f38f694f5c49e7b7 901 SUPERFAMILY SSF55874 503 624 1.31E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 SMART SM00065 39 201 2.2E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 PANTHER PTHR21021:SF19 197 436 7.3E-51 T 16-09-2016 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 SUPERFAMILY SSF55781 39 203 1.48E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 PANTHER PTHR21021 21 50 7.3E-51 T 16-09-2016 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 Pfam PF01590 GAF domain 39 191 5.4E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 Gene3D G3DSA:3.30.450.40 28 199 1.3E-19 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 PANTHER PTHR21021:SF19 21 50 7.3E-51 T 16-09-2016 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 SUPERFAMILY SSF81606 234 436 7.06E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 SMART SM00331 221 436 1.8E-27 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 249 436 6.3E-45 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00110 19509b3d66813b6d48bef4ae7747edce 439 PANTHER PTHR21021 197 436 7.3E-51 T 16-09-2016 Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 SUPERFAMILY SSF55729 11 265 1.06E-36 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 Gene3D G3DSA:3.40.630.30 149 210 5.0E-6 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 Pfam PF13673 Acetyltransferase (GNAT) domain 76 131 1.0E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 PANTHER PTHR21471 16 281 1.5E-42 T 16-09-2016 Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 Gene3D G3DSA:3.40.630.30 10 130 3.8E-15 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16385 c8fbf3a919a23ee6bd965a8ca3a709eb 288 PANTHER PTHR21471:SF60 16 281 1.5E-42 T 16-09-2016 Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 SUPERFAMILY SSF54909 28 86 1.36E-6 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 SUPERFAMILY SSF54909 133 216 2.64E-13 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 Pfam PF03992 Antibiotic biosynthesis monooxygenase 29 90 6.2E-5 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 Pfam PF03992 Antibiotic biosynthesis monooxygenase 129 213 7.6E-19 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 Gene3D G3DSA:3.30.70.900 20 114 1.0E-20 T 16-09-2016 Spa2297_RS07620 3fa4548b1083bc746a08eec81ec7d0c8 234 Gene3D G3DSA:3.30.70.900 123 231 4.0E-33 T 16-09-2016 Spa2297_RS16295 e9f07de20c469c7ca52ca7ba282cd557 501 PANTHER PTHR30365:SF0 1 360 1.7E-217 T 16-09-2016 Spa2297_RS16295 e9f07de20c469c7ca52ca7ba282cd557 501 PANTHER PTHR30365:SF0 387 491 1.7E-217 T 16-09-2016 Spa2297_RS16295 e9f07de20c469c7ca52ca7ba282cd557 501 PANTHER PTHR30365 387 491 1.7E-217 T 16-09-2016 Spa2297_RS16295 e9f07de20c469c7ca52ca7ba282cd557 501 PANTHER PTHR30365 1 360 1.7E-217 T 16-09-2016 Spa2297_RS16295 e9f07de20c469c7ca52ca7ba282cd557 501 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 472 1.2E-176 T 16-09-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 Spa2297_RS16260 fd612a1aa43e3bf0bdfb73433edcadda 182 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 169 1.8E-41 T 16-09-2016 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 Spa2297_RS16260 fd612a1aa43e3bf0bdfb73433edcadda 182 SUPERFAMILY SSF56399 7 178 2.45E-61 T 16-09-2016 Spa2297_RS16260 fd612a1aa43e3bf0bdfb73433edcadda 182 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 176 34.945 T 16-09-2016 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 Spa2297_RS16260 fd612a1aa43e3bf0bdfb73433edcadda 182 PANTHER PTHR12684 1 177 9.8E-63 T 16-09-2016 Spa2297_RS16260 fd612a1aa43e3bf0bdfb73433edcadda 182 PANTHER PTHR12684:SF2 1 177 9.8E-63 T 16-09-2016 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 Gene3D G3DSA:1.10.10.60 12 62 7.1E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 Gene3D G3DSA:1.10.357.10 64 206 1.4E-23 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 66 4.3E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 PANTHER PTHR30055 8 214 2.9E-60 T 16-09-2016 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 PANTHER PTHR30055:SF10 8 214 2.9E-60 T 16-09-2016 Spa2297_RS01880 0b8a6d6b058e1831e83732e8dc0287bc 226 SUPERFAMILY SSF46689 13 93 1.56E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 SUPERFAMILY SSF46689 37 98 2.87E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 Gene3D G3DSA:3.40.50.10490 88 264 1.9E-10 T 16-09-2016 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 SUPERFAMILY SSF53697 117 300 5.46E-13 T 16-09-2016 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 Gene3D G3DSA:1.10.10.10 37 87 2.5E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 PANTHER PTHR30514:SF3 14 305 8.9E-113 T 16-09-2016 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 PANTHER PTHR30514 14 305 8.9E-113 T 16-09-2016 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 Pfam PF01418 Helix-turn-helix domain, rpiR family 40 97 3.0E-14 T 16-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spa2297_RS30080 5fffe0955885fa3824f48661987bd1e2 305 Pfam PF01380 SIS domain 154 275 9.4E-9 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS12475 3263ec203ab4af7c825b5591ebfd13e5 105 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 104 17.806 T 16-09-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS Spa2297_RS12475 3263ec203ab4af7c825b5591ebfd13e5 105 PANTHER PTHR33473 16 104 9.1E-34 T 16-09-2016 Spa2297_RS12475 3263ec203ab4af7c825b5591ebfd13e5 105 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 29 98 3.7E-23 T 16-09-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 Spa2297_RS12475 3263ec203ab4af7c825b5591ebfd13e5 105 SUPERFAMILY SSF54736 26 101 9.42E-26 T 16-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spa2297_RS12475 3263ec203ab4af7c825b5591ebfd13e5 105 Gene3D G3DSA:3.30.1390.10 13 103 1.3E-30 T 16-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 PANTHER PTHR23514:SF13 1 386 2.3E-136 T 16-09-2016 Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 SUPERFAMILY SSF103473 10 386 2.35E-41 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 PANTHER PTHR23514 1 386 2.3E-136 T 16-09-2016 Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 Gene3D G3DSA:1.20.1250.20 213 382 1.3E-16 T 16-09-2016 Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 Gene3D G3DSA:1.20.1250.20 13 186 3.7E-13 T 16-09-2016 Spa2297_RS03530 496151a9f6427e897b15371019e7917c 391 Pfam PF07690 Major Facilitator Superfamily 23 224 7.9E-15 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS15755 a524bf67449ab60a27720308223795a6 84 Pfam PF11273 Protein of unknown function (DUF3073) 2 63 5.6E-22 T 16-09-2016 IPR021426 Protein of unknown function DUF3073 Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 PANTHER PTHR13696:SF68 77 397 5.5E-138 T 16-09-2016 Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 SUPERFAMILY SSF52540 150 385 6.43E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 SUPERFAMILY SSF52172 3 130 3.08E-9 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 PANTHER PTHR13696 77 397 5.5E-138 T 16-09-2016 Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 Gene3D G3DSA:3.40.50.2300 4 128 9.4E-9 T 16-09-2016 Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 152 331 9.1E-23 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS21165 c2eea5ff0b369bedf2b4f8f741b3ba96 418 Gene3D G3DSA:3.40.50.300 149 385 3.6E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 SUPERFAMILY SSF51569 4 339 2.64E-94 T 16-09-2016 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 339 4.4E-77 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 PANTHER PTHR30559 1 342 2.0E-214 T 16-09-2016 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 PIRSF PIRSF001359 5 341 8.1E-62 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 Gene3D G3DSA:3.20.20.70 2 340 1.8E-115 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 5.4E-128 T 16-09-2016 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 PANTHER PTHR30559:SF0 1 342 2.0E-214 T 16-09-2016 Spa2297_RS17575 9c3e5a503f532672dfbbb7c705a48ec2 343 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 340 1.7E-68 T 16-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spa2297_RS24865 b87fad238996d18b817211ae4b853c51 250 Pfam PF12502 Protein of unknown function (DUF3710) 46 219 1.7E-59 T 16-09-2016 IPR022183 Protein of unknown function DUF3710 Spa2297_RS15180 bc8e631b5a1191f2d31eb087efffd809 261 SUPERFAMILY SSF53335 26 179 3.94E-9 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15180 bc8e631b5a1191f2d31eb087efffd809 261 Gene3D G3DSA:3.40.50.150 31 144 4.3E-5 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 Gene3D G3DSA:3.10.105.10 287 495 4.5E-37 T 16-09-2016 Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 414 1.3E-70 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 PANTHER PTHR30290:SF24 12 525 3.8E-201 T 16-09-2016 Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 SUPERFAMILY SSF53850 45 505 1.07E-108 T 16-09-2016 Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 Gene3D G3DSA:3.90.76.10 60 216 2.3E-37 T 16-09-2016 Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 PANTHER PTHR30290 12 525 3.8E-201 T 16-09-2016 Spa2297_RS01025 924fc91d53c70fec006a8d8ffc2a41a5 525 PIRSF PIRSF002741 16 517 3.0E-85 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 SUPERFAMILY SSF55021 745 798 1.12E-6 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Pfam PF01966 HD domain 435 552 1.4E-11 T 16-09-2016 IPR006674 HD domain Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 SUPERFAMILY SSF81593 172 281 7.85E-7 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 818 91.056 T 16-09-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 23 618 8.8E-213 T 16-09-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Pfam PF08335 GlnD PII-uridylyltransferase 210 281 4.7E-7 T 16-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 SUPERFAMILY SSF109604 402 531 1.1E-13 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Pfam PF01909 Nucleotidyltransferase domain 62 121 1.3E-4 T 16-09-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Gene3D G3DSA:3.30.460.10 64 123 2.4E-5 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 PANTHER PTHR13734 340 619 4.0E-93 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 SMART SM00471 430 562 3.6E-7 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 SUPERFAMILY SSF81301 50 158 2.03E-15 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Gene3D G3DSA:3.30.70.260 745 797 1.8E-7 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 PANTHER PTHR13734:SF45 340 619 4.0E-93 T 16-09-2016 Spa2297_RS23720 041b5ffaeaeaf0719109900b64c2fe98 818 Gene3D G3DSA:1.10.3210.10 417 576 4.0E-19 T 16-09-2016 IPR006674 HD domain Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 16-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Pfam PF00108 Thiolase, N-terminal domain 7 265 8.0E-77 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Pfam PF02803 Thiolase, C-terminal domain 274 394 5.0E-45 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 PANTHER PTHR18919 1 395 6.4E-229 T 16-09-2016 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 PIRSF PIRSF000429 2 395 1.9E-137 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Gene3D G3DSA:3.40.47.10 151 199 3.5E-62 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Gene3D G3DSA:3.40.47.10 279 394 3.5E-62 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 SUPERFAMILY SSF53901 6 272 1.33E-79 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 PANTHER PTHR18919:SF91 1 395 6.4E-229 T 16-09-2016 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 SUPERFAMILY SSF53901 275 394 1.64E-41 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Gene3D G3DSA:3.40.47.10 200 277 4.4E-65 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 Gene3D G3DSA:3.40.47.10 6 125 4.4E-65 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 16-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 2.7E-139 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS28395 026286c4bf403cde9a483671451a2ec2 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 125 131 - T 16-09-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 76 154 1.3E-32 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 70 5.0E-7 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 PANTHER PTHR10815 3 154 4.6E-56 T 16-09-2016 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 158 37.667 T 16-09-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 SUPERFAMILY SSF53155 4 79 1.1E-16 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 154 2.1E-34 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 Gene3D G3DSA:1.10.10.10 74 155 1.8E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 SUPERFAMILY SSF46767 74 154 1.83E-32 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26885 6c0f1715b38e035a42bd86abee6115b4 164 PANTHER PTHR10815:SF5 3 154 4.6E-56 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Pfam PF00501 AMP-binding enzyme 42 452 9.6E-83 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Gene3D G3DSA:3.40.50.980 197 351 2.1E-36 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 PANTHER PTHR24096:SF53 10 550 1.2E-266 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 PANTHER PTHR24096 10 550 1.2E-266 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Gene3D G3DSA:3.30.300.30 447 548 3.0E-29 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 538 1.3E-18 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 SUPERFAMILY SSF56801 19 550 3.01E-133 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Gene3D G3DSA:3.40.50.980 30 196 6.6E-28 T 16-09-2016 Spa2297_RS16100 db015cf2833264649a6aa2c001a5f2e6 558 Gene3D G3DSA:2.30.38.10 365 446 9.8E-18 T 16-09-2016 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:1.10.10.160 177 251 1.2E-25 T 16-09-2016 IPR013986 DExx box DNA helicase domain Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:3.40.50.300 69 173 8.0E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:3.40.50.300 252 364 8.0E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Pfam PF00580 UvrD/REP helicase N-terminal domain 73 350 6.8E-78 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 PANTHER PTHR11070 68 829 4.4E-236 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 69 827 0.0 T 16-09-2016 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 SUPERFAMILY SSF52540 69 726 4.25E-178 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Pfam PF13361 UvrD-like helicase C-terminal domain 356 699 5.1E-69 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:1.10.486.10 468 623 1.5E-48 T 16-09-2016 Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:3.40.50.300 365 467 7.2E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 Gene3D G3DSA:3.40.50.300 637 728 7.2E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20245 c2527464fd5ee8abbd0094c4ef1af8ea 829 PANTHER PTHR11070:SF7 68 829 4.4E-236 T 16-09-2016 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 PANTHER PTHR11785:SF342 247 487 2.9E-167 T 16-09-2016 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 PANTHER PTHR11785 247 487 2.9E-167 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 PANTHER PTHR11785:SF342 3 220 2.9E-167 T 16-09-2016 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 Pfam PF13520 Amino acid permease 30 472 3.4E-53 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 PANTHER PTHR11785 3 220 2.9E-167 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS25285 d9c072838c338bca6d0a89a17262bc62 501 PIRSF PIRSF006060 4 495 2.1E-93 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 SUPERFAMILY SSF55811 5 172 3.25E-29 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 SUPERFAMILY SSF46785 175 245 7.07E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 PRINTS PR00502 NUDIX hydrolase family signature 43 57 3.3E-5 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 PRINTS PR00502 NUDIX hydrolase family signature 57 72 3.3E-5 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 PANTHER PTHR22769:SF42 1 227 2.7E-83 T 16-09-2016 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 Gene3D G3DSA:3.90.79.10 3 163 1.9E-49 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 PANTHER PTHR22769 1 227 2.7E-83 T 16-09-2016 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 Pfam PF00293 NUDIX domain 14 137 1.1E-19 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS24640 5a140653c875c8ca3aba96a073c3468b 252 Gene3D G3DSA:1.10.10.10 167 240 4.7E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 Pfam PF00583 Acetyltransferase (GNAT) family 133 187 1.8E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 SUPERFAMILY SSF55729 7 195 4.87E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 PANTHER PTHR13170 1 206 1.7E-75 T 16-09-2016 Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 PANTHER PTHR13170:SF15 1 206 1.7E-75 T 16-09-2016 Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 Gene3D G3DSA:3.40.630.30 3 77 3.7E-35 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01830 1129edf58420d96f0bcdcbdd5cf1f521 210 Gene3D G3DSA:3.40.630.30 125 191 3.7E-35 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 SMART SM00876 232 322 7.5E-33 T 16-09-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 SMART SM00729 55 261 1.8E-38 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 Pfam PF04055 Radical SAM superfamily 65 220 9.3E-15 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 SUPERFAMILY SSF102114 16 321 1.96E-79 T 16-09-2016 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 2.1E-14 T 16-09-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 PANTHER PTHR22976:SF1 1 323 1.4E-149 T 16-09-2016 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 Hamap MF_01694 Biotin synthase [bioB]. 15 323 40.054 T 16-09-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 Gene3D G3DSA:3.20.20.70 16 322 8.1E-90 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 PANTHER PTHR22976 1 323 1.4E-149 T 16-09-2016 Spa2297_RS04535 cf0f88e71e66b59e84b237c6c2cca06c 406 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 1.8E-113 T 16-09-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 Spa2297_RS00775 553b519ada7bdb9c0ddd8ae1f34d2899 244 SUPERFAMILY SSF53335 9 218 6.35E-39 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00775 553b519ada7bdb9c0ddd8ae1f34d2899 244 PANTHER PTHR10108 17 214 1.5E-27 T 16-09-2016 Spa2297_RS00775 553b519ada7bdb9c0ddd8ae1f34d2899 244 Pfam PF01209 ubiE/COQ5 methyltransferase family 3 216 1.6E-17 T 16-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS00775 553b519ada7bdb9c0ddd8ae1f34d2899 244 Gene3D G3DSA:3.40.50.150 11 216 2.4E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 PANTHER PTHR33221 2 132 1.2E-55 T 16-09-2016 Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 SUPERFAMILY SSF46785 2 133 9.58E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 Gene3D G3DSA:1.10.10.10 2 132 1.0E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 PANTHER PTHR33221:SF4 2 132 1.2E-55 T 16-09-2016 Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 Pfam PF02082 Transcriptional regulator 2 83 2.8E-15 T 16-09-2016 IPR000944 Transcription regulator Rrf2-type Spa2297_RS01605 e83698a3eec2631dc999a6adba02e99b 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 131 1.4E-24 T 16-09-2016 IPR000944 Transcription regulator Rrf2-type Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 355 2.6E-29 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 SUPERFAMILY SSF52518 5 213 6.99E-28 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 577 6.8E-39 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 7 619 1.7E-267 T 16-09-2016 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22|UniPathway: UPA00076 Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Gene3D G3DSA:3.40.50.970 389 613 4.3E-55 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 PANTHER PTHR18968 1 618 0.0 T 16-09-2016 Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 SUPERFAMILY SSF52467 184 382 9.43E-41 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 201 1.4E-32 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Gene3D G3DSA:3.40.50.1220 213 366 3.2E-39 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 SUPERFAMILY SSF52518 398 605 1.75E-46 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 Gene3D G3DSA:3.40.50.970 3 212 8.9E-56 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS28460 90f0c6e3c894b40522baea398fc9fcd6 622 PANTHER PTHR18968:SF9 1 618 0.0 T 16-09-2016 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22|UniPathway: UPA00076 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 PANTHER PTHR26402:SF316 2 229 5.1E-86 T 16-09-2016 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 Pfam PF00072 Response regulator receiver domain 4 112 2.0E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 SMART SM00448 2 112 1.1E-36 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 Gene3D G3DSA:3.40.50.2300 1 120 5.0E-37 T 16-09-2016 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 SMART SM00862 150 225 1.2E-25 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 PANTHER PTHR26402 2 229 5.1E-86 T 16-09-2016 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 1.8E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 Gene3D G3DSA:1.10.10.10 128 226 3.1E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30835 d274039467fa084083cd358a7d29778d 229 SUPERFAMILY SSF52172 1 185 5.27E-39 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 SUPERFAMILY SSF53807 46 336 1.46E-47 T 16-09-2016 Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 Pfam PF01497 Periplasmic binding protein 71 313 4.9E-34 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 PANTHER PTHR30535:SF7 45 336 7.6E-143 T 16-09-2016 Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 Gene3D G3DSA:3.40.50.1980 55 188 2.4E-15 T 16-09-2016 Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 PANTHER PTHR30535 45 336 7.6E-143 T 16-09-2016 Spa2297_RS00635 87d3e9b6b7e17ea630580bcfa8e16123 340 Gene3D G3DSA:3.40.50.1980 203 336 5.5E-30 T 16-09-2016 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 PANTHER PTHR30193 7 238 2.4E-92 T 16-09-2016 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 Gene3D G3DSA:1.10.3720.10 9 302 1.1E-54 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 PANTHER PTHR30193 257 314 2.4E-92 T 16-09-2016 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 240 3.2E-9 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 PANTHER PTHR30193:SF6 7 238 2.4E-92 T 16-09-2016 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 SUPERFAMILY SSF161098 58 299 6.41E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11260 8bd775aed6ca97375cd138656588412a 314 PANTHER PTHR30193:SF6 257 314 2.4E-92 T 16-09-2016 Spa2297_RS27160 fa3f62251792f7fa75dd5c833fa32aba 138 PANTHER PTHR21366 1 135 5.3E-48 T 16-09-2016 Spa2297_RS27160 fa3f62251792f7fa75dd5c833fa32aba 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 132 1.0E-13 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS27160 fa3f62251792f7fa75dd5c833fa32aba 138 SUPERFAMILY SSF54593 6 135 5.91E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27160 fa3f62251792f7fa75dd5c833fa32aba 138 PANTHER PTHR21366:SF12 1 135 5.3E-48 T 16-09-2016 Spa2297_RS27160 fa3f62251792f7fa75dd5c833fa32aba 138 Gene3D G3DSA:3.10.180.10 1 135 2.1E-29 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 349 414 2.8E-14 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 102 162 1.5E-18 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 PRINTS PR00397 Sirohaem Fe-binding site signature 471 489 2.8E-9 T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 PRINTS PR00397 Sirohaem Fe-binding site signature 426 444 2.8E-9 T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 PANTHER PTHR32439:SF0 1 564 3.9E-215 T 16-09-2016 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Gene3D G3DSA:3.90.480.10 102 170 3.7E-48 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Gene3D G3DSA:3.90.480.10 342 418 3.7E-48 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 SUPERFAMILY SSF56014 173 340 8.9E-47 T 16-09-2016 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 SUPERFAMILY SSF56014 422 563 8.64E-37 T 16-09-2016 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Gene3D G3DSA:3.30.413.10 173 328 3.2E-44 T 16-09-2016 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 SUPERFAMILY SSF55124 305 437 1.96E-20 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 328 9.5E-41 T 16-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 426 562 2.0E-10 T 16-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 PANTHER PTHR32439 1 564 3.9E-215 T 16-09-2016 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 SUPERFAMILY SSF55124 22 172 4.25E-37 T 16-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 471 487 - T 16-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 Spa2297_RS25785 f50a60956329f4c95f7acd1dfd5a3026 565 Gene3D G3DSA:3.30.413.10 424 563 2.6E-37 T 16-09-2016 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 2.5E-149 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 Gene3D G3DSA:3.40.1060.10 155 288 1.1E-40 T 16-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 Gene3D G3DSA:3.30.499.10 2 154 2.3E-22 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 Gene3D G3DSA:3.30.499.10 326 466 6.7E-57 T 16-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PANTHER PTHR11670:SF38 327 460 1.7E-254 T 16-09-2016 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 SUPERFAMILY SSF53732 1 465 2.09E-160 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PANTHER PTHR11670:SF38 1 307 1.7E-254 T 16-09-2016 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 16-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 4.9E-225 T 16-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 108 116 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 343 354 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 286 300 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 209 222 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 133 148 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 119 132 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 399 412 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 82 95 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PRINTS PR00415 Aconitase family signature 195 208 8.9E-47 T 16-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 58.992 T 16-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PANTHER PTHR11670 1 307 1.7E-254 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23545 11331db7eeba7745cc3d0b395a5c4904 476 PANTHER PTHR11670 327 460 1.7E-254 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS31285 4cd9274c778f938147af1b4a111e9276 250 Pfam PF03746 LamB/YcsF family 2 240 6.8E-96 T 16-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF Spa2297_RS31285 4cd9274c778f938147af1b4a111e9276 250 PANTHER PTHR30292:SF0 1 250 2.5E-120 T 16-09-2016 Spa2297_RS31285 4cd9274c778f938147af1b4a111e9276 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 244 41.25 T 16-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF Spa2297_RS31285 4cd9274c778f938147af1b4a111e9276 250 SUPERFAMILY SSF88713 2 249 2.3E-89 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS31285 4cd9274c778f938147af1b4a111e9276 250 PANTHER PTHR30292 1 250 2.5E-120 T 16-09-2016 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 Gene3D G3DSA:3.40.309.10 288 465 3.0E-65 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 PANTHER PTHR11699:SF202 10 537 0.0 T 16-09-2016 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 PANTHER PTHR11699 10 537 0.0 T 16-09-2016 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 SUPERFAMILY SSF53720 40 504 4.32E-144 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 Gene3D G3DSA:3.40.605.10 44 287 1.2E-71 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20165 af09681e8f95ea676d78fe874d1bb658 537 Pfam PF00171 Aldehyde dehydrogenase family 45 501 3.2E-144 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 PANTHER PTHR10795 42 334 2.0E-54 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 113 6.8E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 60 79 6.8E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 PRINTS PR00723 Subtilisin serine protease family (S8) signature 272 288 6.8E-16 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 Pfam PF00082 Subtilase family 60 323 2.2E-45 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 49 394 3.6E-100 T 16-09-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 65 76 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 Gene3D G3DSA:3.40.50.200 35 334 6.0E-79 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 SUPERFAMILY SSF52743 42 335 3.14E-80 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS06190 acfa869ad6f7f9de0708b33da3596f42 398 PANTHER PTHR10795:SF419 42 334 2.0E-54 T 16-09-2016 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 PANTHER PTHR10245:SF20 1 274 1.4E-115 T 16-09-2016 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 SUPERFAMILY SSF47413 1 57 2.52E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 PANTHER PTHR10245 1 274 1.4E-115 T 16-09-2016 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 Pfam PF13560 Helix-turn-helix domain 3 62 1.0E-12 T 16-09-2016 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 Gene3D G3DSA:1.10.260.40 2 57 5.5E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18105 2a553b34e679c4495296697ec011baa2 274 SMART SM00530 6 61 2.9E-4 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 884 1217 3.4E-126 T 16-09-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Gene3D G3DSA:3.40.109.10 652 861 5.8E-51 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 SUPERFAMILY SSF55469 658 862 2.22E-52 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 PANTHER PTHR21712:SF4 828 1220 2.6E-105 T 16-09-2016 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 650 855 1.3E-92 T 16-09-2016 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 PANTHER PTHR21712:SF4 17 30 2.6E-105 T 16-09-2016 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Gene3D G3DSA:3.40.50.10210 944 1200 1.8E-113 T 16-09-2016 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Gene3D G3DSA:1.10.1610.10 872 943 6.0E-29 T 16-09-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Pfam PF02277 Phosphoribosyltransferase 880 1217 9.5E-127 T 16-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 SUPERFAMILY SSF52733 875 1218 6.02E-114 T 16-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 PANTHER PTHR21712 828 1220 2.6E-105 T 16-09-2016 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 PANTHER PTHR21712 17 30 2.6E-105 T 16-09-2016 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 882 1219 34.957 T 16-09-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS05950 314731fd624eafddcdf464ee32015b7a 1220 Pfam PF00881 Nitroreductase family 662 829 3.4E-31 T 16-09-2016 IPR029479 Nitroreductase Spa2297_RS02565 1e649d41b670e236598359941b2f7312 143 SUPERFAMILY SSF51182 27 130 8.69E-11 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS02565 1e649d41b670e236598359941b2f7312 143 Gene3D G3DSA:2.60.120.10 43 128 2.3E-10 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS02565 1e649d41b670e236598359941b2f7312 143 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 11 22 - T 16-09-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 PANTHER PTHR10108 3 25 2.8E-13 T 16-09-2016 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 PANTHER PTHR10108 41 145 2.8E-13 T 16-09-2016 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 PANTHER PTHR10108:SF705 3 25 2.8E-13 T 16-09-2016 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 PANTHER PTHR10108:SF705 41 145 2.8E-13 T 16-09-2016 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 SUPERFAMILY SSF53335 14 189 1.55E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 Pfam PF13649 Methyltransferase domain 47 142 9.8E-15 T 16-09-2016 Spa2297_RS00210 97c3eaf7ffc89c2e6b2691d6c3c8eef7 201 Gene3D G3DSA:3.40.50.150 15 180 4.3E-30 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS01455 a3b41f092a35e717c40333b73b28b1c9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 277 9.1E-25 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01455 a3b41f092a35e717c40333b73b28b1c9 286 PANTHER PTHR30151:SF8 42 286 6.0E-65 T 16-09-2016 Spa2297_RS01455 a3b41f092a35e717c40333b73b28b1c9 286 Gene3D G3DSA:1.10.3720.10 86 277 7.2E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01455 a3b41f092a35e717c40333b73b28b1c9 286 PANTHER PTHR30151 42 286 6.0E-65 T 16-09-2016 Spa2297_RS01455 a3b41f092a35e717c40333b73b28b1c9 286 SUPERFAMILY SSF161098 84 269 2.09E-29 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 PANTHER PTHR10314 29 196 1.6E-36 T 16-09-2016 Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 SUPERFAMILY SSF53686 28 298 6.63E-46 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 Gene3D G3DSA:3.40.50.1100 97 298 2.2E-38 T 16-09-2016 Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 PIRSF PIRSF006278 2 301 2.1E-81 T 16-09-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 298 9.2E-18 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS22205 26d7ad4c2ca305a8ca3a9fa1f231b884 302 PANTHER PTHR10314:SF105 29 196 1.6E-36 T 16-09-2016 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 SUPERFAMILY SSF55486 244 470 4.98E-52 T 16-09-2016 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PANTHER PTHR11533 44 470 3.8E-96 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 Pfam PF01433 Peptidase family M1 57 287 2.4E-23 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 Pfam PF01433 Peptidase family M1 319 367 1.5E-17 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 338 4.6E-12 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 342 354 4.6E-12 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 170 185 4.6E-12 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 217 232 4.6E-12 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 PANTHER PTHR11533:SF163 44 470 3.8E-96 T 16-09-2016 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 Gene3D G3DSA:1.10.390.10 336 471 7.2E-22 T 16-09-2016 Spa2297_RS28050 aa584202287d7d114de36d8bc48099ee 505 SUPERFAMILY SSF63737 41 233 2.75E-37 T 16-09-2016 Spa2297_RS18845 eaa7ed600ca05049cdf79bed7642cadf 301 Pfam PF01040 UbiA prenyltransferase family 36 276 6.2E-54 T 16-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 Spa2297_RS18845 eaa7ed600ca05049cdf79bed7642cadf 301 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 16 295 3.9E-90 T 16-09-2016 IPR006371 4-hydroxybenzoate polyprenyltransferase-related Spa2297_RS18845 eaa7ed600ca05049cdf79bed7642cadf 301 PANTHER PTHR11048:SF7 18 297 5.6E-72 T 16-09-2016 Spa2297_RS18845 eaa7ed600ca05049cdf79bed7642cadf 301 PANTHER PTHR11048 18 297 5.6E-72 T 16-09-2016 Spa2297_RS18315 25cbecb3eef1e5fe05df07705ed0d35a 124 SUPERFAMILY SSF46785 1 103 2.88E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18315 25cbecb3eef1e5fe05df07705ed0d35a 124 Gene3D G3DSA:1.10.10.10 1 68 3.7E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18315 25cbecb3eef1e5fe05df07705ed0d35a 124 PANTHER PTHR34134 1 114 3.6E-38 T 16-09-2016 Spa2297_RS18315 25cbecb3eef1e5fe05df07705ed0d35a 124 Pfam PF03965 Penicillinase repressor 1 102 7.2E-21 T 16-09-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 Spa2297_RS18315 25cbecb3eef1e5fe05df07705ed0d35a 124 PANTHER PTHR34134:SF1 1 114 3.6E-38 T 16-09-2016 Spa2297_RS31210 509bf90852e9484ae05937f3dba5d353 275 PANTHER PTHR32243:SF18 6 275 2.3E-94 T 16-09-2016 Spa2297_RS31210 509bf90852e9484ae05937f3dba5d353 275 PANTHER PTHR32243 6 275 2.3E-94 T 16-09-2016 Spa2297_RS31210 509bf90852e9484ae05937f3dba5d353 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 261 1.7E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31210 509bf90852e9484ae05937f3dba5d353 275 SUPERFAMILY SSF161098 6 274 6.26E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31210 509bf90852e9484ae05937f3dba5d353 275 Gene3D G3DSA:1.10.3720.10 6 262 3.1E-54 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS13950 dc9b1aeced1dc41c72f5d5e04e81c770 253 SUPERFAMILY SSF53213 1 253 1.01E-81 T 16-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Spa2297_RS13950 dc9b1aeced1dc41c72f5d5e04e81c770 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 21 227 8.2E-43 T 16-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Spa2297_RS13950 dc9b1aeced1dc41c72f5d5e04e81c770 253 Gene3D G3DSA:3.40.830.10 1 234 6.2E-83 T 16-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Spa2297_RS13950 dc9b1aeced1dc41c72f5d5e04e81c770 253 PIRSF PIRSF006157 1 253 9.9E-82 T 16-09-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 Spa2297_RS13950 dc9b1aeced1dc41c72f5d5e04e81c770 253 PANTHER PTHR30096 1 253 4.2E-91 T 16-09-2016 Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 SUPERFAMILY SSF52091 3 110 4.71E-31 T 16-09-2016 IPR002645 STAS domain Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 Gene3D G3DSA:3.30.750.24 4 111 2.4E-40 T 16-09-2016 IPR002645 STAS domain Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 PANTHER PTHR33495 2 111 3.0E-42 T 16-09-2016 Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 107 1.1E-32 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 Pfam PF01740 STAS domain 12 108 1.2E-17 T 16-09-2016 IPR002645 STAS domain Spa2297_RS17965 9fe9ceff32a4e55f52672858c1f6a607 113 PANTHER PTHR33495:SF2 2 111 3.0E-42 T 16-09-2016 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 Gene3D G3DSA:3.75.10.10 2 344 1.6E-116 T 16-09-2016 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 9 342 1.6E-104 T 16-09-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 PANTHER PTHR31377 2 344 3.1E-125 T 16-09-2016 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 SUPERFAMILY SSF55909 2 343 4.82E-116 T 16-09-2016 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 Hamap MF_01841 Agmatine deiminase [aguA]. 1 343 48.146 T 16-09-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 Spa2297_RS23400 2b094070958549ad849f605589c2b78c 347 PANTHER PTHR31377:SF0 2 344 3.1E-125 T 16-09-2016 Spa2297_RS29310 51fb69fab930eb8032972832a9726f25 208 SUPERFAMILY SSF53335 10 164 4.06E-22 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29310 51fb69fab930eb8032972832a9726f25 208 Pfam PF05401 Nodulation protein S (NodS) 18 144 1.9E-14 T 16-09-2016 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS29310 51fb69fab930eb8032972832a9726f25 208 Gene3D G3DSA:3.40.50.150 12 169 8.2E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Pfam PF00501 AMP-binding enzyme 24 427 1.4E-100 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Gene3D G3DSA:2.30.38.10 342 418 5.4E-28 T 16-09-2016 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Gene3D G3DSA:3.30.300.30 424 520 2.3E-29 T 16-09-2016 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 512 3.7E-16 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 SUPERFAMILY SSF56801 10 520 9.16E-150 T 16-09-2016 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Gene3D G3DSA:3.40.50.980 16 181 5.5E-34 T 16-09-2016 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 PANTHER PTHR24096 1 519 1.7E-202 T 16-09-2016 Spa2297_RS14490 be93c7b7a453e3840393bd6f727ecc64 522 Gene3D G3DSA:3.40.50.980 182 341 8.0E-50 T 16-09-2016 Spa2297_RS05305 98bd71862568e19c8acc3caf28589b30 604 SUPERFAMILY SSF52540 245 482 8.42E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05305 98bd71862568e19c8acc3caf28589b30 604 Gene3D G3DSA:3.40.50.300 230 478 7.5E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 PANTHER PTHR11609:SF1 4 298 5.0E-111 T 16-09-2016 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 PANTHER PTHR11609 4 298 5.0E-111 T 16-09-2016 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 Gene3D G3DSA:3.30.200.20 11 115 2.1E-42 T 16-09-2016 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 19 298 2.6E-72 T 16-09-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 16-09-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 16-09-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 SUPERFAMILY SSF56104 13 298 4.58E-98 T 16-09-2016 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 Gene3D G3DSA:3.30.470.20 116 247 1.2E-54 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 295 25.155 T 16-09-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS15845 a78e278012a879e9e78d074c7552b2e9 299 Pfam PF01259 SAICAR synthetase 18 269 2.5E-101 T 16-09-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS07000 f167a137031571fe5ea38c6966769a09 211 SUPERFAMILY SSF55811 12 185 1.12E-43 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS07000 f167a137031571fe5ea38c6966769a09 211 PANTHER PTHR11839 11 209 2.2E-88 T 16-09-2016 Spa2297_RS07000 f167a137031571fe5ea38c6966769a09 211 Pfam PF00293 NUDIX domain 51 164 5.0E-17 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS07000 f167a137031571fe5ea38c6966769a09 211 Gene3D G3DSA:3.90.79.10 12 186 1.6E-48 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS07000 f167a137031571fe5ea38c6966769a09 211 PANTHER PTHR11839:SF9 11 209 2.2E-88 T 16-09-2016 Spa2297_RS26145 fa03eea48b38e973f9f982f301dbf247 273 SUPERFAMILY SSF53067 124 251 4.17E-7 T 16-09-2016 Spa2297_RS26145 fa03eea48b38e973f9f982f301dbf247 273 SUPERFAMILY SSF53067 26 85 4.17E-7 T 16-09-2016 Spa2297_RS26145 fa03eea48b38e973f9f982f301dbf247 273 Gene3D G3DSA:3.30.420.40 23 149 4.6E-7 T 16-09-2016 Spa2297_RS26145 fa03eea48b38e973f9f982f301dbf247 273 Gene3D G3DSA:3.30.420.40 150 228 1.0E-6 T 16-09-2016 Spa2297_RS26145 fa03eea48b38e973f9f982f301dbf247 273 Pfam PF06723 MreB/Mbl protein 60 178 1.1E-7 T 16-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 Spa2297_RS28920 861a9208f4684c0c757347c6e3a2840f 473 PANTHER PTHR14463:SF9 1 467 0.0 T 16-09-2016 Spa2297_RS28920 861a9208f4684c0c757347c6e3a2840f 473 Pfam PF06762 Lipase maturation factor 284 465 1.5E-62 T 16-09-2016 IPR009613 Lipase maturation factor Spa2297_RS28920 861a9208f4684c0c757347c6e3a2840f 473 Pfam PF06762 Lipase maturation factor 121 267 5.2E-58 T 16-09-2016 IPR009613 Lipase maturation factor Spa2297_RS28920 861a9208f4684c0c757347c6e3a2840f 473 PANTHER PTHR14463 1 467 0.0 T 16-09-2016 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 SUPERFAMILY SSF55846 258 444 1.44E-49 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 SMART SM00701 258 406 8.1E-64 T 16-09-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 PANTHER PTHR11022:SF41 420 442 1.2E-51 T 16-09-2016 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 PANTHER PTHR11022:SF41 252 401 1.2E-51 T 16-09-2016 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 SMART SM00644 272 433 0.0072 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 281 433 6.9E-14 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 PANTHER PTHR11022 420 442 1.2E-51 T 16-09-2016 IPR015510 Peptidoglycan recognition protein GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 PANTHER PTHR11022 252 401 1.2E-51 T 16-09-2016 IPR015510 Peptidoglycan recognition protein GO:0008745|GO:0009253 Spa2297_RS13165 cdc744ba94c822fd7342e9a2430aa098 453 Gene3D G3DSA:3.40.80.10 255 449 7.5E-50 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS15895 c528a70a76d19b4a06638509f80400be 163 Gene3D G3DSA:2.60.120.10 3 162 4.7E-48 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS15895 c528a70a76d19b4a06638509f80400be 163 PANTHER PTHR33387:SF3 2 163 1.4E-47 T 16-09-2016 Spa2297_RS15895 c528a70a76d19b4a06638509f80400be 163 Pfam PF06172 Cupin superfamily (DUF985) 9 139 2.3E-35 T 16-09-2016 IPR009327 Cupin domain of unknown function DUF985 Spa2297_RS15895 c528a70a76d19b4a06638509f80400be 163 PANTHER PTHR33387 2 163 1.4E-47 T 16-09-2016 Spa2297_RS15895 c528a70a76d19b4a06638509f80400be 163 SUPERFAMILY SSF51182 3 161 5.34E-45 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS04790 1e898a22831d1a2da1001732983e7da6 135 SUPERFAMILY SSF51735 17 134 1.04E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04790 1e898a22831d1a2da1001732983e7da6 135 PANTHER PTHR33303 1 135 4.0E-44 T 16-09-2016 Spa2297_RS04790 1e898a22831d1a2da1001732983e7da6 135 Gene3D G3DSA:3.40.50.720 17 134 6.3E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04790 1e898a22831d1a2da1001732983e7da6 135 SMART SM00881 12 105 8.2E-20 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS04790 1e898a22831d1a2da1001732983e7da6 135 Pfam PF13380 CoA binding domain 18 131 3.8E-37 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Pfam PF13424 Tetratricopeptide repeat 924 987 4.6E-11 T 16-09-2016 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Pfam PF13424 Tetratricopeptide repeat 1048 1122 2.0E-11 T 16-09-2016 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 SUPERFAMILY SSF48452 958 1077 1.35E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Pfam PF13374 Tetratricopeptide repeat 882 918 0.0025 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Pfam PF13374 Tetratricopeptide repeat 1009 1046 2.6E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 SUPERFAMILY SSF52540 365 617 9.66E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 SUPERFAMILY SSF48452 1044 1162 5.54E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 PANTHER PTHR19959:SF128 749 1168 5.0E-41 T 16-09-2016 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 PANTHER PTHR19959 749 1168 5.0E-41 T 16-09-2016 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Gene3D G3DSA:1.25.40.10 897 1150 2.4E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Gene3D G3DSA:1.25.40.10 806 861 2.4E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 Pfam PF00931 NB-ARC domain 391 539 4.6E-7 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 SUPERFAMILY SSF48452 807 831 1.97E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS27480 9149c5e9b03de512467c731bd6bb093b 1201 SUPERFAMILY SSF48452 870 955 1.97E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 SUPERFAMILY SSF48498 74 213 1.07E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 Gene3D G3DSA:1.10.357.10 67 213 1.2E-36 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 211 7.4E-36 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 SUPERFAMILY SSF46689 3 70 5.34E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PANTHER PTHR30055:SF36 2 135 2.0E-28 T 16-09-2016 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PANTHER PTHR30055 2 135 2.0E-28 T 16-09-2016 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 Gene3D G3DSA:1.10.10.60 3 66 1.5E-23 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.4E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00400 Tetracycline repressor protein signature 136 155 8.3E-18 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00400 Tetracycline repressor protein signature 100 123 8.3E-18 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00400 Tetracycline repressor protein signature 195 209 8.3E-18 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00400 Tetracycline repressor protein signature 26 49 8.3E-18 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS20590 56b3d36868d567e6058ee6d868999780 216 PRINTS PR00400 Tetracycline repressor protein signature 80 99 8.3E-18 T 16-09-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 PANTHER PTHR21366 1 138 2.5E-40 T 16-09-2016 Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 Gene3D G3DSA:3.10.180.10 1 136 3.9E-39 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 PANTHER PTHR21366:SF0 1 138 2.5E-40 T 16-09-2016 Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 3.6E-22 T 16-09-2016 Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 SUPERFAMILY SSF54593 1 138 5.36E-35 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS22820 684cbe6a4bd0dfbe2b9ed97cb7ae4a4c 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 2.3E-44 T 16-09-2016 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 240 254 2.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 2.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 Pfam PF12697 Alpha/beta hydrolase family 44 287 1.8E-21 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 Gene3D G3DSA:3.40.50.1820 18 293 8.3E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 PANTHER PTHR10992 19 297 4.3E-45 T 16-09-2016 Spa2297_RS13800 ce960ea2471410307615934cc47fe13f 314 SUPERFAMILY SSF53474 15 293 3.85E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 27 213 1.2E-108 T 16-09-2016 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 201 8.5E-27 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 Pfam PF08281 Sigma-70, region 4 148 198 9.2E-14 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 Pfam PF04542 Sigma-70 region 2 43 106 4.5E-18 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 SUPERFAMILY SSF88946 34 121 4.45E-24 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 61 92 - T 16-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 SUPERFAMILY SSF88659 141 203 2.99E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 Gene3D G3DSA:1.10.1740.10 30 108 1.3E-28 T 16-09-2016 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 Gene3D G3DSA:1.10.10.10 141 205 3.2E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 PANTHER PTHR30173 33 209 2.8E-51 T 16-09-2016 Spa2297_RS22060 b54201994704f0a30bb23e45af862a14 227 PANTHER PTHR30173:SF9 33 209 2.8E-51 T 16-09-2016 Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 PANTHER PTHR30388:SF4 171 375 1.7E-145 T 16-09-2016 Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 Pfam PF13478 XdhC Rossmann domain 206 348 2.8E-39 T 16-09-2016 IPR027051 XdhC Rossmann domain Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 PANTHER PTHR30388 1 124 1.7E-145 T 16-09-2016 Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 PANTHER PTHR30388 171 375 1.7E-145 T 16-09-2016 Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 Pfam PF02625 XdhC and CoxI family 11 78 7.2E-23 T 16-09-2016 IPR003777 XdhC- CoxI Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 Pfam PF02625 XdhC and CoxI family 120 183 4.4E-10 T 16-09-2016 IPR003777 XdhC- CoxI Spa2297_RS26185 834fd5ebb70b471032e715742c8a28c0 383 PANTHER PTHR30388:SF4 1 124 1.7E-145 T 16-09-2016 Spa2297_RS15685 d809a6e88cd3d17195f3f8d50388156b 511 PANTHER PTHR11785:SF286 1 492 6.3E-186 T 16-09-2016 Spa2297_RS15685 d809a6e88cd3d17195f3f8d50388156b 511 Pfam PF13520 Amino acid permease 32 471 4.8E-67 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS15685 d809a6e88cd3d17195f3f8d50388156b 511 PIRSF PIRSF006060 15 508 1.2E-66 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS15685 d809a6e88cd3d17195f3f8d50388156b 511 PANTHER PTHR11785 1 492 6.3E-186 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS16695 c871d2f3ae7dc0e9e07b8359803bc326 84 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 84 22.496 T 16-09-2016 IPR009619 Cell division protein CrgA Spa2297_RS16695 c871d2f3ae7dc0e9e07b8359803bc326 84 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 84 2.7E-29 T 16-09-2016 IPR009619 Cell division protein CrgA Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 154 1.2E-49 T 16-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 PANTHER PTHR10173:SF6 3 154 2.6E-68 T 16-09-2016 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 PANTHER PTHR10173 3 154 2.6E-68 T 16-09-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 160 33.895 T 16-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 Pfam PF01625 Peptide methionine sulfoxide reductase 8 154 7.7E-57 T 16-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 SUPERFAMILY SSF55068 3 163 5.36E-65 T 16-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Spa2297_RS20950 0644a701dee4708b3239828d147d8302 170 Gene3D G3DSA:3.30.1060.10 3 155 1.3E-65 T 16-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Gene3D G3DSA:3.40.47.10 129 180 2.3E-53 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Gene3D G3DSA:3.40.47.10 264 379 2.3E-53 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 ProSitePatterns PS00099 Thiolases active site. 361 374 - T 16-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 71 89 - T 16-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 ProSitePatterns PS00737 Thiolases signature 2. 326 342 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 SUPERFAMILY SSF53901 2 257 7.83E-81 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 PIRSF PIRSF000429 1 381 4.0E-112 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 PANTHER PTHR18919 1 381 2.5E-203 T 16-09-2016 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Gene3D G3DSA:3.40.47.10 2 110 8.7E-68 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Gene3D G3DSA:3.40.47.10 181 263 8.7E-68 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 3 377 8.6E-131 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Pfam PF02803 Thiolase, C-terminal domain 258 378 5.4E-43 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 Pfam PF00108 Thiolase, N-terminal domain 1 249 3.9E-91 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 PANTHER PTHR18919:SF95 1 381 2.5E-203 T 16-09-2016 Spa2297_RS22825 a3e7a4e4051f09e038d2cd0bdb47c271 382 SUPERFAMILY SSF53901 259 378 4.61E-34 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Pfam PF16124 RecQ zinc-binding 357 420 8.7E-17 T 16-09-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SMART SM00956 427 533 6.2E-47 T 16-09-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Pfam PF00570 HRDC domain 564 627 1.4E-20 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Pfam PF09382 RQC domain 422 536 6.1E-36 T 16-09-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 PANTHER PTHR13710 23 665 2.9E-299 T 16-09-2016 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SMART SM00490 264 345 1.8E-23 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Gene3D G3DSA:1.10.10.10 359 536 1.2E-55 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Pfam PF00270 DEAD/DEAH box helicase 43 198 2.7E-15 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SUPERFAMILY SSF52540 25 213 9.02E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Gene3D G3DSA:1.10.150.80 560 632 1.3E-17 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Gene3D G3DSA:3.40.50.300 24 217 3.1E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SMART SM00487 35 231 1.3E-28 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 PANTHER PTHR13710:SF81 23 665 2.9E-299 T 16-09-2016 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SUPERFAMILY SSF47819 559 630 5.67E-22 T 16-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SMART SM00341 558 638 2.7E-11 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 SUPERFAMILY SSF52540 221 479 2.77E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 29 627 3.8E-224 T 16-09-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Pfam PF00271 Helicase conserved C-terminal domain 239 345 4.9E-15 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 30 483 1.4E-149 T 16-09-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Spa2297_RS19270 f9cd1f91e8c9089b56d3389ade5ca69c 665 Gene3D G3DSA:3.40.50.300 220 358 2.1E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 127 138 - T 16-09-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 17 378 41.437 T 16-09-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 PANTHER PTHR23132 1 381 3.6E-187 T 16-09-2016 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Gene3D G3DSA:3.30.1490.20 191 248 2.5E-22 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Pfam PF01820 D-ala D-ala ligase N-terminus 18 150 7.8E-34 T 16-09-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Gene3D G3DSA:3.30.470.20 250 380 1.4E-46 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 PIRSF PIRSF039102 15 383 2.2E-110 T 16-09-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Pfam PF07478 D-ala D-ala ligase C-terminus 168 375 4.9E-65 T 16-09-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 320 348 - T 16-09-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 18 377 4.2E-103 T 16-09-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 SUPERFAMILY SSF52440 16 158 3.64E-34 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 PANTHER PTHR23132:SF8 1 381 3.6E-187 T 16-09-2016 Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 Gene3D G3DSA:3.40.50.20 16 149 3.8E-37 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS23585 714a44fb8f0cb17e68fb9e33b75c0aec 385 SUPERFAMILY SSF56059 160 379 1.0E-53 T 16-09-2016 Spa2297_RS07360 cc22aefe046fcd22bf2b0cf6cd600290 375 Gene3D G3DSA:3.40.50.1820 133 369 8.3E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS07360 cc22aefe046fcd22bf2b0cf6cd600290 375 Pfam PF12146 Serine aminopeptidase, S33 158 281 4.0E-7 T 16-09-2016 IPR022742 Serine aminopeptidase, S33 Spa2297_RS07360 cc22aefe046fcd22bf2b0cf6cd600290 375 SUPERFAMILY SSF53474 306 371 2.06E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS07360 cc22aefe046fcd22bf2b0cf6cd600290 375 SUPERFAMILY SSF53474 130 268 2.06E-30 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10345 1e11661a216059d75e4ced8dc4462cf6 215 Gene3D G3DSA:3.30.750.24 24 108 7.9E-7 T 16-09-2016 IPR002645 STAS domain Spa2297_RS10345 1e11661a216059d75e4ced8dc4462cf6 215 SUPERFAMILY SSF52172 44 187 5.96E-12 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS10345 1e11661a216059d75e4ced8dc4462cf6 215 Pfam PF03861 ANTAR domain 135 187 3.8E-19 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS10345 1e11661a216059d75e4ced8dc4462cf6 215 SMART SM01012 133 188 4.2E-20 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS10345 1e11661a216059d75e4ced8dc4462cf6 215 Gene3D G3DSA:1.10.10.10 135 189 7.6E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 670 715 2.5E-8 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 741 771 0.014 T 16-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 SUPERFAMILY SSF101904 514 777 2.49E-40 T 16-09-2016 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 PANTHER PTHR10169:SF48 13 760 7.7E-239 T 16-09-2016 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 SMART SM00434 22 477 8.4E-260 T 16-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Gene3D G3DSA:3.90.199.10 346 411 2.8E-111 T 16-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Gene3D G3DSA:3.90.199.10 42 247 2.8E-111 T 16-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 43 484 9.4E-148 T 16-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 PANTHER PTHR10169 13 760 7.7E-239 T 16-09-2016 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 SUPERFAMILY SSF56719 42 499 1.14E-164 T 16-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Gene3D G3DSA:2.120.10.90 514 807 4.4E-42 T 16-09-2016 Spa2297_RS24740 03dbd1294f92eb2809b5e4cc58218ac8 818 Gene3D G3DSA:3.30.1360.40 248 345 1.1E-27 T 16-09-2016 IPR024946 Arginine repressor C-terminal-like domain Spa2297_RS29355 43a84a0e8895a132fdc3cd9590e07821 140 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 12 137 5.8E-7 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS29355 43a84a0e8895a132fdc3cd9590e07821 140 Gene3D G3DSA:3.30.530.20 11 123 1.1E-5 T 16-09-2016 IPR023393 START-like domain Spa2297_RS29355 43a84a0e8895a132fdc3cd9590e07821 140 SUPERFAMILY SSF55961 1 135 7.85E-11 T 16-09-2016 Spa2297_RS06860 ad8250013769dce9828f4a5d21b42cca 261 PANTHER PTHR41913 4 261 6.3E-86 T 16-09-2016 Spa2297_RS06860 ad8250013769dce9828f4a5d21b42cca 261 Pfam PF07920 Protein of unknown function (DUF1684) 122 258 3.2E-35 T 16-09-2016 IPR012467 Protein of unknown function DUF1684 Spa2297_RS06860 ad8250013769dce9828f4a5d21b42cca 261 PANTHER PTHR41913:SF1 4 261 6.3E-86 T 16-09-2016 Spa2297_RS17875 bf6393eb724dc0fdf5b1474bc7d9c4a0 237 SUPERFAMILY SSF55811 53 212 1.4E-26 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17875 bf6393eb724dc0fdf5b1474bc7d9c4a0 237 Pfam PF00293 NUDIX domain 53 177 1.2E-12 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS17875 bf6393eb724dc0fdf5b1474bc7d9c4a0 237 PANTHER PTHR12992 52 237 5.6E-39 T 16-09-2016 Spa2297_RS17875 bf6393eb724dc0fdf5b1474bc7d9c4a0 237 Gene3D G3DSA:3.90.79.10 52 219 7.3E-36 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Gene3D G3DSA:3.30.2090.10 183 264 5.3E-11 T 16-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Gene3D G3DSA:3.30.70.1430 565 639 1.1E-4 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82866 291 490 2.09E-42 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82693 562 651 2.51E-5 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82714 183 263 1.57E-10 T 16-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Gene3D G3DSA:1.10.3850.10 272 490 1.8E-56 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Gene3D G3DSA:1.10.3850.10 792 1006 1.0E-58 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82693 41 130 5.49E-22 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82866 785 1009 4.05E-50 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Pfam PF00873 AcrB/AcrD/AcrF family 5 1005 7.1E-215 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PANTHER PTHR32063 1 1036 0.0 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82693 267 322 1.05E-13 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 SUPERFAMILY SSF82693 134 180 1.05E-13 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 6.4E-40 T 16-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 PANTHER PTHR32063:SF0 1 1036 0.0 T 16-09-2016 Spa2297_RS08930 22f3ff3b584294a48d3d63c0da86bc0e 1037 Gene3D G3DSA:3.30.70.1430 41 136 1.2E-23 T 16-09-2016 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 PANTHER PTHR10314:SF5 1 329 1.0E-140 T 16-09-2016 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 PANTHER PTHR10314 1 329 1.0E-140 T 16-09-2016 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 Gene3D G3DSA:3.40.50.1100 61 145 2.7E-41 T 16-09-2016 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 TIGRFAM TIGR00260 thrC: threonine synthase 9 326 8.4E-96 T 16-09-2016 IPR004450 Threonine synthase-like Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 SUPERFAMILY SSF53686 5 333 1.96E-100 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 16-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 PIRSF PIRSF038945 1 351 3.1E-166 T 16-09-2016 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1|UniPathway: UPA00050 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 Gene3D G3DSA:3.40.50.1100 146 327 8.5E-49 T 16-09-2016 Spa2297_RS22605 955a8c6b56f48b02643b5356cb82eae9 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 319 3.8E-73 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS29825 98d2e579f2dd2860d51a0362ea89d081 201 Gene3D G3DSA:3.40.50.300 17 193 1.5E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29825 98d2e579f2dd2860d51a0362ea89d081 201 PANTHER PTHR11711:SF117 16 201 1.5E-53 T 16-09-2016 Spa2297_RS29825 98d2e579f2dd2860d51a0362ea89d081 201 PANTHER PTHR11711 16 201 1.5E-53 T 16-09-2016 Spa2297_RS29825 98d2e579f2dd2860d51a0362ea89d081 201 Pfam PF03029 Conserved hypothetical ATP binding protein 24 190 1.1E-21 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS29825 98d2e579f2dd2860d51a0362ea89d081 201 SUPERFAMILY SSF52540 18 192 2.05E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 SUPERFAMILY SSF53335 204 361 6.18E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 PIRSF PIRSF037565 1 378 1.5E-132 T 16-09-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 377 43.851 T 16-09-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 PANTHER PTHR18895:SF6 77 377 1.2E-139 T 16-09-2016 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 Pfam PF05175 Methyltransferase small domain 205 374 2.1E-52 T 16-09-2016 IPR007848 Methyltransferase small domain GO:0008168 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 PANTHER PTHR18895 77 377 1.2E-139 T 16-09-2016 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 Gene3D G3DSA:3.40.50.150 220 375 3.0E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 302 316 6.0E-5 T 16-09-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Spa2297_RS03480 a7a8ae9edf3538062ba33d074eec7c6c 378 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 326 346 6.0E-5 T 16-09-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 PANTHER PTHR11835:SF49 5 348 1.6E-216 T 16-09-2016 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 16-09-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 SMART SM01329 9 344 5.5E-166 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 PANTHER PTHR11835 5 348 1.6E-216 T 16-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 8 348 62.046 T 16-09-2016 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 Gene3D G3DSA:3.40.718.10 9 329 5.9E-114 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 328 1.7E-90 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS23375 b8a9d9ab85bc1d94167175d2a42221ff 350 SUPERFAMILY SSF53659 7 347 1.38E-110 T 16-09-2016 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 SMART SM00530 16 71 1.3E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 PANTHER PTHR10245:SF7 12 270 2.4E-35 T 16-09-2016 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 PANTHER PTHR10245 12 270 2.4E-35 T 16-09-2016 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 SUPERFAMILY SSF47413 10 67 1.31E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 Pfam PF13560 Helix-turn-helix domain 14 69 5.3E-13 T 16-09-2016 Spa2297_RS14285 ed605fb9a5dc4cb9485cee0dd1be830f 270 Gene3D G3DSA:1.10.260.40 12 65 6.8E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 PANTHER PTHR23416:SF58 1 192 2.8E-93 T 16-09-2016 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 SUPERFAMILY SSF51161 14 191 2.63E-51 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 SMART SM01266 14 68 5.3E-13 T 16-09-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 PANTHER PTHR23416 1 192 2.8E-93 T 16-09-2016 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 Gene3D G3DSA:2.160.10.10 12 193 1.1E-57 T 16-09-2016 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 Pfam PF12464 Maltose acetyltransferase 16 67 1.8E-10 T 16-09-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 140 174 2.8E-11 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS01160 8078ad15038ac91afd6583bd01bcbcf4 193 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 148 176 - T 16-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 Spa2297_RS30085 cf0a93a6e83a0eaaf70a776badcff896 215 PANTHER PTHR10285 17 208 1.6E-68 T 16-09-2016 Spa2297_RS30085 cf0a93a6e83a0eaaf70a776badcff896 215 PANTHER PTHR10285:SF81 17 208 1.6E-68 T 16-09-2016 Spa2297_RS30085 cf0a93a6e83a0eaaf70a776badcff896 215 Gene3D G3DSA:3.40.50.300 8 208 2.0E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30085 cf0a93a6e83a0eaaf70a776badcff896 215 Pfam PF03308 ArgK protein 15 50 1.8E-6 T 16-09-2016 Spa2297_RS30085 cf0a93a6e83a0eaaf70a776badcff896 215 SUPERFAMILY SSF52540 19 208 4.92E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25665 ec09b33674a52f95af277c72699bda15 337 SUPERFAMILY SSF55729 169 323 1.7E-10 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25665 ec09b33674a52f95af277c72699bda15 337 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 168 322 1.8E-9 T 16-09-2016 IPR007434 Peptidogalycan biosysnthesis/recognition Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.29 T 16-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 PANTHER PTHR11264:SF5 4 225 1.7E-169 T 16-09-2016 Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 Gene3D G3DSA:3.40.470.10 7 224 2.2E-78 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 SMART SM00987 53 212 3.2E-30 T 16-09-2016 Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 SUPERFAMILY SSF52141 9 224 3.05E-70 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 16-09-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 SMART SM00986 53 212 3.2E-30 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 PANTHER PTHR11264 4 225 1.7E-169 T 16-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Spa2297_RS03730 aa39e9ca0334cfc3474b84d0c1c2aa10 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 211 1.4E-17 T 16-09-2016 IPR005122 Uracil-DNA glycosylase-like Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 PANTHER PTHR38657 1 496 3.2E-219 T 16-09-2016 Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 PANTHER PTHR38657:SF1 1 496 3.2E-219 T 16-09-2016 Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 SUPERFAMILY SSF48173 217 477 1.13E-48 T 16-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 Gene3D G3DSA:1.10.579.10 304 396 3.7E-4 T 16-09-2016 Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 Gene3D G3DSA:1.25.40.80 176 303 4.1E-12 T 16-09-2016 Spa2297_RS00745 85b5b5b9afef4399b1fb8cad1b6bf13f 498 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 3 200 5.6E-38 T 16-09-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 PANTHER PTHR12001:SF45 47 357 2.6E-98 T 16-09-2016 Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 SUPERFAMILY SSF48576 14 355 9.54E-64 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 PANTHER PTHR12001 47 357 2.6E-98 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 Gene3D G3DSA:1.10.600.10 20 356 3.1E-65 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS30765 81f0f6348da8c6c4183da0054758a240 357 Pfam PF00348 Polyprenyl synthetase 45 304 2.3E-44 T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS14205 338c7ff2a9af715159e42796acdce14f 404 SUPERFAMILY SSF103473 18 388 4.01E-22 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14205 338c7ff2a9af715159e42796acdce14f 404 Gene3D G3DSA:1.20.1250.20 12 205 1.4E-12 T 16-09-2016 Spa2297_RS14205 338c7ff2a9af715159e42796acdce14f 404 Gene3D G3DSA:1.20.1250.20 244 384 5.4E-5 T 16-09-2016 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 248 5.2E-42 T 16-09-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Gene3D G3DSA:3.30.300.10 144 250 4.0E-37 T 16-09-2016 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 SUPERFAMILY SSF55973 120 248 2.83E-43 T 16-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 PANTHER PTHR11964 3 395 1.5E-250 T 16-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 SUPERFAMILY SSF55973 3 109 4.32E-44 T 16-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 16-09-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 8.7E-168 T 16-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 3.7E-68 T 16-09-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 56.61 T 16-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Gene3D G3DSA:3.30.300.10 11 143 5.9E-44 T 16-09-2016 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 PIRSF PIRSF000497 1 401 6.5E-163 T 16-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.6E-40 T 16-09-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 16-09-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 SUPERFAMILY SSF55973 250 401 3.22E-68 T 16-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 Spa2297_RS05550 bf8d1bdc5385293901fccf09a2dce4b7 402 Gene3D G3DSA:3.30.300.10 261 400 4.6E-70 T 16-09-2016 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 Gene3D G3DSA:3.30.465.10 62 175 6.3E-28 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 175 5.1E-41 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 SUPERFAMILY SSF55447 181 231 4.4E-5 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 Gene3D G3DSA:3.30.43.10 15 55 5.9E-8 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 SUPERFAMILY SSF56176 10 175 1.99E-39 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 PANTHER PTHR11908 15 260 2.3E-35 T 16-09-2016 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 PANTHER PTHR11908:SF68 15 260 2.3E-35 T 16-09-2016 Spa2297_RS12705 812926f6b12e1f4ff3f5f9e28648386f 297 Gene3D G3DSA:3.30.390.50 182 260 6.6E-5 T 16-09-2016 Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 SUPERFAMILY SSF52540 8 224 1.2E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 PANTHER PTHR24220:SF575 11 223 1.7E-145 T 16-09-2016 Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 PANTHER PTHR24220 11 223 1.7E-145 T 16-09-2016 Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 Pfam PF00005 ABC transporter 25 175 2.9E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 SMART SM00382 34 223 4.4E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS25270 ed7d08abf08044b8d043b7f5a8bfbb0e 263 Gene3D G3DSA:3.40.50.300 7 223 5.6E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 85 165 3.8E-29 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 SUPERFAMILY SSF46767 84 166 7.19E-28 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 12 80 8.4E-6 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 PANTHER PTHR10815:SF5 12 171 4.2E-49 T 16-09-2016 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 Gene3D G3DSA:1.10.10.10 84 167 5.1E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 PANTHER PTHR10815 12 171 4.2E-49 T 16-09-2016 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 86 166 5.6E-30 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS26070 e2d4e26297b3f6e2880088cfe50b813d 172 SUPERFAMILY SSF53155 12 89 2.94E-14 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 76 133 4.7E-7 T 16-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 PANTHER PTHR30349:SF20 269 417 1.1E-52 T 16-09-2016 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 PANTHER PTHR30349:SF20 77 242 1.1E-52 T 16-09-2016 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 Gene3D G3DSA:1.10.150.130 75 176 6.7E-24 T 16-09-2016 IPR023109 Integrase/recombinase, N-terminal Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 PANTHER PTHR30349 77 242 1.1E-52 T 16-09-2016 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 PANTHER PTHR30349 269 417 1.1E-52 T 16-09-2016 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 Gene3D G3DSA:1.10.443.10 183 235 1.7E-37 T 16-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 Gene3D G3DSA:1.10.443.10 272 395 1.7E-37 T 16-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 Pfam PF00589 Phage integrase family 187 387 9.1E-22 T 16-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 SUPERFAMILY SSF56349 75 236 7.65E-63 T 16-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spa2297_RS12615 fcf95429891a4a8b009ef1a90bbb7a45 420 SUPERFAMILY SSF56349 272 395 7.65E-63 T 16-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 Gene3D G3DSA:2.30.110.10 27 178 8.1E-47 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 PANTHER PTHR30466 15 189 6.6E-100 T 16-09-2016 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 SUPERFAMILY SSF50475 27 183 4.12E-43 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 Pfam PF01613 Flavin reductase like domain 37 180 8.0E-35 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 PANTHER PTHR30466:SF5 15 189 6.6E-100 T 16-09-2016 Spa2297_RS04680 3a3f705f8616ed5e7cf504cf7b5f28a6 189 SMART SM00903 35 179 1.6E-45 T 16-09-2016 IPR002563 Flavin reductase like domain GO:0010181 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 PANTHER PTHR10668:SF75 1 515 2.2E-161 T 16-09-2016 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 Gene3D G3DSA:3.50.50.60 208 291 3.7E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 Gene3D G3DSA:3.50.50.60 1 54 3.7E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 Gene3D G3DSA:3.50.50.60 442 488 3.7E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 Gene3D G3DSA:3.50.50.60 115 129 3.7E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 SUPERFAMILY SSF51905 1 309 1.94E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 SUPERFAMILY SSF51905 442 480 1.94E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 PANTHER PTHR10668 1 515 2.2E-161 T 16-09-2016 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 1 490 6.8E-176 T 16-09-2016 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 Pfam PF01593 Flavin containing amine oxidoreductase 8 480 1.8E-58 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS00755 43c7db498ad850ad57a5ed9a3c932b9f 515 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 452 472 - T 16-09-2016 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site Spa2297_RS28095 fbbfd8f162ed159b3113a82eb7dd2a2f 212 Pfam PF01965 DJ-1/PfpI family 2 162 4.6E-28 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS28095 fbbfd8f162ed159b3113a82eb7dd2a2f 212 Gene3D G3DSA:3.40.50.880 2 207 2.5E-69 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS28095 fbbfd8f162ed159b3113a82eb7dd2a2f 212 PANTHER PTHR11019:SF131 1 187 9.1E-80 T 16-09-2016 Spa2297_RS28095 fbbfd8f162ed159b3113a82eb7dd2a2f 212 PANTHER PTHR11019 1 187 9.1E-80 T 16-09-2016 Spa2297_RS28095 fbbfd8f162ed159b3113a82eb7dd2a2f 212 SUPERFAMILY SSF52317 2 183 1.05E-48 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 PANTHER PTHR33705:SF1 1 90 1.2E-36 T 16-09-2016 Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 5.3E-20 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 PANTHER PTHR33705 1 90 1.2E-36 T 16-09-2016 Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 SUPERFAMILY SSF55594 1 88 3.27E-18 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 Gene3D G3DSA:3.30.1340.10 1 88 1.4E-22 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 16-09-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 7.3E-24 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 6.6E-10 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 6.6E-10 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS24765 767e2c931061a5a0bbfca4a36e9c9600 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 6.6E-10 T 16-09-2016 IPR000032 Phosphocarrier HPr protein-like Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 PIRSF PIRSF001109 1 485 7.7E-195 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SMART SM00997 243 405 1.7E-110 T 16-09-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 16-09-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SMART SM00996 9 484 0.0 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 3.8E-149 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 16-09-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Gene3D G3DSA:3.40.50.720 245 404 3.1E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 1.2E-83 T 16-09-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 PANTHER PTHR23420:SF6 193 485 0.0 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 49.983 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Gene3D G3DSA:3.40.50.1480 406 485 1.7E-148 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 Gene3D G3DSA:3.40.50.1480 8 244 1.7E-148 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SUPERFAMILY SSF52283 7 157 6.23E-115 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SUPERFAMILY SSF52283 406 485 6.23E-115 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SUPERFAMILY SSF52283 195 242 6.23E-115 T 16-09-2016 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 SUPERFAMILY SSF51735 243 405 4.32E-78 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 PANTHER PTHR23420 193 485 0.0 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 PANTHER PTHR23420 1 155 0.0 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 1.6E-193 T 16-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 Spa2297_RS13085 4b369d0f2a962ca7af9ca525a54acc67 485 PANTHER PTHR23420:SF6 1 155 0.0 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 4.7E-12 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 295 4.7E-12 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 264 279 4.7E-12 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 4.7E-12 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PANTHER PTHR13789 3 405 6.0E-84 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 Gene3D G3DSA:3.50.50.60 98 166 6.4E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 Gene3D G3DSA:3.50.50.60 254 348 6.4E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 Gene3D G3DSA:3.50.50.60 3 44 6.4E-40 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 Pfam PF01494 FAD binding domain 129 318 2.8E-9 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 PANTHER PTHR13789:SF186 3 405 6.0E-84 T 16-09-2016 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 SUPERFAMILY SSF51905 251 354 2.59E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02260 bfc406e95e37222a0703eb9c5c911bf9 409 SUPERFAMILY SSF51905 4 150 2.59E-43 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09640 2164ed7715a9c4e55f867715314626a0 410 PANTHER PTHR24421:SF22 48 408 2.7E-160 T 16-09-2016 Spa2297_RS09640 2164ed7715a9c4e55f867715314626a0 410 SUPERFAMILY SSF55874 285 393 2.29E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09640 2164ed7715a9c4e55f867715314626a0 410 Pfam PF07730 Histidine kinase 206 272 2.4E-16 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS09640 2164ed7715a9c4e55f867715314626a0 410 PANTHER PTHR24421 48 408 2.7E-160 T 16-09-2016 Spa2297_RS09640 2164ed7715a9c4e55f867715314626a0 410 Gene3D G3DSA:3.30.565.10 301 394 8.4E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29715 57235d9aae5a928c40c81aca9df4ccf5 241 PANTHER PTHR13343 121 236 3.7E-21 T 16-09-2016 Spa2297_RS29715 57235d9aae5a928c40c81aca9df4ccf5 241 Gene3D G3DSA:3.20.180.10 135 225 2.1E-7 T 16-09-2016 IPR019595 Domain of unknown function DUF2470 Spa2297_RS29715 57235d9aae5a928c40c81aca9df4ccf5 241 SUPERFAMILY SSF50475 14 224 9.81E-15 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29715 57235d9aae5a928c40c81aca9df4ccf5 241 Pfam PF10615 Protein of unknown function (DUF2470) 142 216 1.7E-8 T 16-09-2016 IPR019595 Domain of unknown function DUF2470 Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 Pfam PF13185 GAF domain 21 163 2.2E-17 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 Gene3D G3DSA:3.30.450.40 10 172 1.8E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 PIRSF PIRSF036625 1 229 9.9E-99 T 16-09-2016 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 SUPERFAMILY SSF52172 164 222 1.99E-8 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 Pfam PF03861 ANTAR domain 170 222 5.3E-19 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 Gene3D G3DSA:1.10.10.10 173 228 6.1E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 SUPERFAMILY SSF55781 23 175 3.71E-18 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01625 26215fe3ebdba1c5f43db76d701bfa9f 229 SMART SM01012 168 223 4.9E-20 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS07465 02be5bc092a8040f17c75fa201fe3012 157 Gene3D G3DSA:3.40.630.30 2 138 3.3E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS07465 02be5bc092a8040f17c75fa201fe3012 157 Pfam PF00583 Acetyltransferase (GNAT) family 55 133 9.6E-14 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS07465 02be5bc092a8040f17c75fa201fe3012 157 SUPERFAMILY SSF55729 1 140 2.4E-26 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS07465 02be5bc092a8040f17c75fa201fe3012 157 PANTHER PTHR23091 1 155 1.8E-20 T 16-09-2016 Spa2297_RS00340 2d6aca2cd3230ee457c982d3cb416636 319 Gene3D G3DSA:1.10.3720.10 34 310 5.2E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00340 2d6aca2cd3230ee457c982d3cb416636 319 PANTHER PTHR30193:SF15 15 313 4.9E-123 T 16-09-2016 Spa2297_RS00340 2d6aca2cd3230ee457c982d3cb416636 319 PANTHER PTHR30193 15 313 4.9E-123 T 16-09-2016 Spa2297_RS00340 2d6aca2cd3230ee457c982d3cb416636 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 309 2.4E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00340 2d6aca2cd3230ee457c982d3cb416636 319 SUPERFAMILY SSF161098 81 307 4.06E-54 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 SMART SM00331 486 707 9.6E-35 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 PANTHER PTHR21021:SF19 203 298 1.7E-52 T 16-09-2016 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 PANTHER PTHR21021:SF19 461 710 1.7E-52 T 16-09-2016 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Pfam PF13185 GAF domain 325 454 4.7E-7 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Pfam PF13185 GAF domain 139 284 7.2E-15 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 PANTHER PTHR21021 203 298 1.7E-52 T 16-09-2016 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 PANTHER PTHR21021 461 710 1.7E-52 T 16-09-2016 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 SUPERFAMILY SSF55781 117 285 8.83E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Gene3D G3DSA:3.30.450.40 310 462 2.8E-21 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 SMART SM00065 140 293 4.0E-14 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 SMART SM00065 328 465 7.5E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Pfam PF08448 PAS fold 17 120 8.4E-7 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 512 706 6.8E-42 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Gene3D G3DSA:3.30.450.40 116 297 8.6E-22 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 Gene3D G3DSA:3.30.450.20 2 114 3.7E-5 T 16-09-2016 Spa2297_RS00170 ee39e76730e0dabef0537431f40d8615 710 SUPERFAMILY SSF55781 323 463 2.18E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS20780 8fc08245b0d0f59050d6ece289201c77 200 Gene3D G3DSA:3.40.50.300 1 165 1.2E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20780 8fc08245b0d0f59050d6ece289201c77 200 SUPERFAMILY SSF52540 1 131 9.59E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20780 8fc08245b0d0f59050d6ece289201c77 200 PANTHER PTHR10285 1 115 4.4E-12 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 PANTHER PTHR10098 466 644 1.0E-26 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 PANTHER PTHR10098 38 43 1.0E-26 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 PRINTS PR00364 Disease resistance protein signature 216 230 2.2E-5 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 PRINTS PR00364 Disease resistance protein signature 55 70 2.2E-5 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 PRINTS PR00364 Disease resistance protein signature 131 145 2.2E-5 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SMART SM00028 468 501 84.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SMART SM00028 588 621 33.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SMART SM00028 508 541 160.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SMART SM00028 548 581 53.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 Pfam PF13424 Tetratricopeptide repeat 468 538 6.4E-9 T 16-09-2016 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 Gene3D G3DSA:1.25.40.10 455 643 1.7E-18 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SUPERFAMILY SSF48452 468 646 4.3E-18 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 SUPERFAMILY SSF52540 15 272 3.76E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 Gene3D G3DSA:3.40.50.300 51 147 1.2E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06995 1e88b4f049bd99215d620d7bd59f8d7d 675 Pfam PF00931 NB-ARC domain 48 234 8.3E-9 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Gene3D G3DSA:2.140.10.10 485 790 1.6E-56 T 16-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Gene3D G3DSA:2.140.10.10 411 451 1.6E-56 T 16-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00220 16 270 3.1E-37 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Gene3D G3DSA:1.10.510.10 99 263 1.8E-39 T 16-09-2016 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 PANTHER PTHR24362 3 358 9.7E-98 T 16-09-2016 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 PANTHER PTHR24362:SF282 3 358 9.7E-98 T 16-09-2016 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SUPERFAMILY SSF50998 468 751 3.4E-42 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Pfam PF13360 PQQ-like domain 475 631 2.1E-18 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Pfam PF13360 PQQ-like domain 644 791 1.6E-21 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SUPERFAMILY SSF56112 12 272 4.59E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 439 468 480.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 555 586 5.2E-6 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 646 677 4.4E-5 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 600 631 26.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 726 757 3.6 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 765 797 3.9E-4 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 511 543 58.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 686 717 8.1 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 SMART SM00564 473 504 83.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Pfam PF00069 Protein kinase domain 16 261 7.4E-37 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS14340 44956af8ad6746a5164561180e31ea64 797 Gene3D G3DSA:3.30.200.20 6 82 5.8E-12 T 16-09-2016 Spa2297_RS03140 47ba66604ef5713c7b6b11bde3c12dba 139 PANTHER PTHR28259 12 139 5.6E-34 T 16-09-2016 Spa2297_RS03140 47ba66604ef5713c7b6b11bde3c12dba 139 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 14 123 6.0E-21 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS03140 47ba66604ef5713c7b6b11bde3c12dba 139 TIGRFAM TIGR00494 crcB: protein CrcB 14 126 2.7E-23 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS03140 47ba66604ef5713c7b6b11bde3c12dba 139 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 12 129 18.521 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 PANTHER PTHR12358 1 322 1.5E-158 T 16-09-2016 Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 PANTHER PTHR12358:SF34 1 322 1.5E-158 T 16-09-2016 Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 Gene3D G3DSA:3.40.50.10330 5 78 1.8E-4 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 SUPERFAMILY SSF111331 1 322 1.59E-49 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 126 2.3E-25 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS22175 2e1dd2082d77fdb156466c289ec2bd9d 322 SMART SM00046 2 133 2.7E-7 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS10630 03b16109bfabd21f1cfb24ab2171876d 256 PANTHER PTHR10867:SF14 3 138 2.0E-67 T 16-09-2016 Spa2297_RS10630 03b16109bfabd21f1cfb24ab2171876d 256 SUPERFAMILY SSF53335 11 248 4.71E-15 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS10630 03b16109bfabd21f1cfb24ab2171876d 256 Gene3D G3DSA:3.40.50.150 12 250 6.3E-21 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS10630 03b16109bfabd21f1cfb24ab2171876d 256 PANTHER PTHR10867 3 138 2.0E-67 T 16-09-2016 IPR000940 Methyltransferase, NNMT/PNMT/TEMT GO:0008168 Spa2297_RS10630 03b16109bfabd21f1cfb24ab2171876d 256 Pfam PF01234 NNMT/PNMT/TEMT family 16 245 1.1E-8 T 16-09-2016 IPR000940 Methyltransferase, NNMT/PNMT/TEMT GO:0008168 Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 PANTHER PTHR31223 33 248 7.0E-98 T 16-09-2016 Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 Gene3D G3DSA:3.40.50.450 53 248 1.2E-63 T 16-09-2016 Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 PANTHER PTHR31223:SF1 33 248 7.0E-98 T 16-09-2016 Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 74 247 2.4E-41 T 16-09-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 Pfam PF03641 Possible lysine decarboxylase 116 244 2.2E-34 T 16-09-2016 IPR031100 LOG family Spa2297_RS21670 a0893fa2f8c193fd5f3931466d81bb65 252 SUPERFAMILY SSF102405 43 245 1.01E-63 T 16-09-2016 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 SMART SM00382 45 234 8.1E-22 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 Pfam PF00005 ABC transporter 36 185 3.4E-39 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 PANTHER PTHR24220 22 261 2.2E-118 T 16-09-2016 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 PANTHER PTHR24220:SF447 22 261 2.2E-118 T 16-09-2016 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 SUPERFAMILY SSF52540 20 256 7.99E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 21 261 1.4E-105 T 16-09-2016 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 PIRSF PIRSF039085 17 261 8.0E-98 T 16-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Spa2297_RS12090 c3765bb6cfbf9a20db963192044239d7 261 Gene3D G3DSA:3.40.50.300 20 258 1.9E-87 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 PANTHER PTHR30173 1 319 7.5E-135 T 16-09-2016 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 SUPERFAMILY SSF88659 135 195 5.98E-8 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 SUPERFAMILY SSF88946 26 108 5.49E-13 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 Gene3D G3DSA:3.10.450.50 203 316 1.7E-6 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 Gene3D G3DSA:1.10.10.10 135 195 6.8E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 Pfam PF04542 Sigma-70 region 2 28 92 1.1E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 SUPERFAMILY SSF54427 204 319 4.12E-11 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 PANTHER PTHR30173:SF11 1 319 7.5E-135 T 16-09-2016 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 Gene3D G3DSA:1.10.1740.10 30 109 7.7E-12 T 16-09-2016 Spa2297_RS28760 e38f496e2f073b9ee301012b55dc61a7 322 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 194 1.7E-12 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 Gene3D G3DSA:1.20.1250.20 25 205 1.8E-34 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 Gene3D G3DSA:1.20.1250.20 477 503 1.7E-22 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 Gene3D G3DSA:1.20.1250.20 273 431 1.7E-22 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 Pfam PF07690 Major Facilitator Superfamily 28 420 1.1E-51 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PANTHER PTHR23501 17 505 9.6E-201 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 SUPERFAMILY SSF103473 258 430 1.96E-72 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 SUPERFAMILY SSF103473 18 208 1.96E-72 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 SUPERFAMILY SSF103473 476 500 1.96E-72 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PANTHER PTHR23501:SF73 17 505 9.6E-201 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 498 4.0E-82 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 212 230 2.7E-11 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 2.7E-11 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 2.7E-11 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 2.7E-11 T 16-09-2016 Spa2297_RS18360 f62e5587ae0eb6bdf76e43391c87356a 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 2.7E-11 T 16-09-2016 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 Pfam PF00817 impB/mucB/samB family 13 89 2.0E-5 T 16-09-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 Gene3D G3DSA:3.30.70.270 13 94 8.6E-5 T 16-09-2016 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 SUPERFAMILY SSF100879 193 280 1.1E-13 T 16-09-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 Pfam PF11799 impB/mucB/samB family C-terminal domain 209 297 3.5E-11 T 16-09-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 PANTHER PTHR11076 13 299 3.0E-42 T 16-09-2016 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 SUPERFAMILY SSF56672 12 168 5.23E-29 T 16-09-2016 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 Gene3D G3DSA:3.30.1490.100 194 296 3.0E-14 T 16-09-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS06835 8d68d8dde922c72b79e4811614ce9cf7 334 Gene3D G3DSA:1.10.150.20 104 171 9.8E-17 T 16-09-2016 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Gene3D G3DSA:3.40.50.140 111 169 1.1E-6 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 PANTHER PTHR30446:SF0 1 199 1.2E-119 T 16-09-2016 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 SUPERFAMILY SSF111304 3 197 2.75E-75 T 16-09-2016 IPR023627 Recombination protein RecR Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 SMART SM00493 79 164 4.3E-18 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Pfam PF13662 Toprim domain 80 170 2.6E-26 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Gene3D G3DSA:3.90.79.10 50 110 6.0E-4 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 16-09-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.6E-85 T 16-09-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 3.5E-6 T 16-09-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 109.374 T 16-09-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 PANTHER PTHR30446 1 199 1.2E-119 T 16-09-2016 Spa2297_RS17725 89ce1082b2b44058ab5ba239ae013a9a 199 Pfam PF02132 RecR protein 38 77 5.5E-16 T 16-09-2016 IPR023628 Recombination protein RecR, C4-type zinc finger Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PANTHER PTHR11206 199 487 8.8E-14 T 16-09-2016 Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PANTHER PTHR11206 61 74 8.8E-14 T 16-09-2016 Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PANTHER PTHR11206:SF90 61 74 8.8E-14 T 16-09-2016 Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PANTHER PTHR11206:SF90 199 487 8.8E-14 T 16-09-2016 Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 Pfam PF03023 MviN-like protein 16 453 3.7E-56 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 398 415 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 121 145 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 40 56 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 145 166 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 248 274 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 21 40 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS11460 6bbf09a7dd2e070035804f1b164dcbe2 537 PRINTS PR01806 Virulence factor MviN signature 345 364 2.7E-19 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 600 618 - T 16-09-2016 IPR028299 ClpA/B, conserved site 2 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 691 1.9E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 644 662 1.9E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 1.9E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 570 588 1.9E-40 T 16-09-2016 IPR001270 ClpA/B family GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 733 812 8.6E-22 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 55 102 2.9E-8 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 126 175 1.7E-9 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Gene3D G3DSA:3.40.50.300 520 743 1.8E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 PANTHER PTHR11638 34 818 0.0 T 16-09-2016 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SUPERFAMILY SSF81923 42 175 2.35E-16 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SUPERFAMILY SSF52540 195 464 3.34E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Gene3D G3DSA:1.10.8.60 744 831 2.8E-27 T 16-09-2016 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Gene3D G3DSA:1.10.8.60 378 462 1.1E-31 T 16-09-2016 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Gene3D G3DSA:1.10.1780.10 42 168 2.4E-24 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SMART SM01086 733 822 1.1E-30 T 16-09-2016 IPR019489 Clp ATPase, C-terminal Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 237 351 1.0E-12 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 329 341 - T 16-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Pfam PF07724 AAA domain (Cdc48 subfamily) 565 727 1.7E-54 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SMART SM00382 232 378 1.1E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SMART SM00382 566 798 5.0E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 Gene3D G3DSA:3.40.50.300 193 377 7.5E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01140 ed769b5bb36beaaf269ecd6157653ae4 838 SUPERFAMILY SSF52540 515 812 1.63E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 SUPERFAMILY SSF51735 1 260 3.97E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PANTHER PTHR24322:SF242 155 186 1.2E-47 T 16-09-2016 Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PANTHER PTHR24322:SF242 11 139 1.2E-47 T 16-09-2016 Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.8E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 201 3.3E-5 T 16-09-2016 Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 Gene3D G3DSA:3.40.50.720 1 260 4.1E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 260 1.1E-50 T 16-09-2016 Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PANTHER PTHR24322 155 186 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS15345 88d0bbbdedb51fc0dbf123b33a23f3ab 261 PANTHER PTHR24322 11 139 1.2E-47 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 Gene3D G3DSA:3.50.50.60 3 174 7.1E-14 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 Gene3D G3DSA:3.50.50.60 293 328 7.1E-14 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 SUPERFAMILY SSF51905 289 332 1.07E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 SUPERFAMILY SSF51905 2 169 1.07E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 PANTHER PTHR10617:SF114 1 446 5.1E-92 T 16-09-2016 Spa2297_RS10280 a5db6264f61b1809b5ca261cecd9eaf8 453 PANTHER PTHR10617 1 446 5.1E-92 T 16-09-2016 Spa2297_RS02370 cb9daa7bc5b4e6ecce73906a90a59563 192 PANTHER PTHR30543 1 192 3.3E-32 T 16-09-2016 Spa2297_RS02370 cb9daa7bc5b4e6ecce73906a90a59563 192 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 1.2E-67 T 16-09-2016 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 Spa2297_RS02370 cb9daa7bc5b4e6ecce73906a90a59563 192 Pfam PF03358 NADPH-dependent FMN reductase 4 143 2.0E-31 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS02370 cb9daa7bc5b4e6ecce73906a90a59563 192 SUPERFAMILY SSF52218 3 170 8.07E-33 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS02370 cb9daa7bc5b4e6ecce73906a90a59563 192 Gene3D G3DSA:3.40.50.360 1 174 2.1E-33 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS09935 449ec029341678f293f42320846763f9 388 SUPERFAMILY SSF51621 35 251 1.88E-27 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS09935 449ec029341678f293f42320846763f9 388 SUPERFAMILY SSF51621 282 315 1.88E-27 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS09935 449ec029341678f293f42320846763f9 388 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 371 1.5E-128 T 16-09-2016 Spa2297_RS09935 449ec029341678f293f42320846763f9 388 PANTHER PTHR32308 1 276 1.4E-13 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS09935 449ec029341678f293f42320846763f9 388 PANTHER PTHR32308 301 376 1.4E-13 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS09935 449ec029341678f293f42320846763f9 388 Gene3D G3DSA:3.20.20.60 36 315 4.5E-40 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS09935 449ec029341678f293f42320846763f9 388 PIRSF PIRSF015582 14 381 1.7E-85 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS22050 4dbb6b3bedeaffe5660b7b258cde8dd2 271 Pfam PF02586 SOS response associated peptidase (SRAP) 1 251 1.7E-67 T 16-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS22050 4dbb6b3bedeaffe5660b7b258cde8dd2 271 Gene3D G3DSA:3.90.1680.10 1 261 1.6E-75 T 16-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS22050 4dbb6b3bedeaffe5660b7b258cde8dd2 271 PANTHER PTHR13604 2 267 2.0E-78 T 16-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS22050 4dbb6b3bedeaffe5660b7b258cde8dd2 271 SUPERFAMILY SSF143081 2 261 3.27E-65 T 16-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS25440 381c0c0777f821f44fedf1f9a6f722b6 190 SUPERFAMILY SSF55729 48 189 5.15E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25440 381c0c0777f821f44fedf1f9a6f722b6 190 Pfam PF00583 Acetyltransferase (GNAT) family 66 143 3.3E-8 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS25440 381c0c0777f821f44fedf1f9a6f722b6 190 Gene3D G3DSA:3.40.630.30 46 189 2.5E-16 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02040 ce01057abc6034c73f559002a576ff88 123 SUPERFAMILY SSF50346 10 120 4.32E-18 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PANTHER PTHR24322:SF602 12 141 4.0E-41 T 16-09-2016 Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 SUPERFAMILY SSF51735 5 259 1.73E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 180 0.0032 T 16-09-2016 Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 Gene3D G3DSA:3.40.50.720 4 258 5.8E-66 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PANTHER PTHR24322:SF602 157 188 4.0E-41 T 16-09-2016 Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.3E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.3E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PANTHER PTHR24322 157 188 4.0E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PANTHER PTHR24322 12 141 4.0E-41 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 Pfam PF00106 short chain dehydrogenase 9 197 2.1E-42 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS11960 d5d1fac869418881f2430b7bbdac4653 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 8.6E-28 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Gene3D G3DSA:1.20.140.10 271 443 5.1E-46 T 16-09-2016 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Gene3D G3DSA:2.40.110.10 173 270 5.6E-33 T 16-09-2016 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Gene3D G3DSA:1.10.540.10 34 172 1.1E-26 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 64 169 5.5E-18 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 SUPERFAMILY SSF47203 282 441 4.83E-33 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 PANTHER PTHR10909 29 461 2.4E-149 T 16-09-2016 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 440 1.3E-28 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 174 270 4.1E-21 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 SUPERFAMILY SSF56645 38 292 9.82E-59 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS24100 178d572dbf9d10406617eed45d66ff8f 648 PANTHER PTHR10909:SF145 29 461 2.4E-149 T 16-09-2016 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SMART SM00065 229 376 1.0E-7 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SMART SM00065 60 208 4.3E-18 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SUPERFAMILY SSF55781 211 393 1.9E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Gene3D G3DSA:3.30.565.10 472 579 1.6E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Gene3D G3DSA:3.30.450.40 210 373 4.9E-22 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 575 7.5E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SMART SM00387 489 579 1.0E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Pfam PF13185 GAF domain 59 199 1.5E-18 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Pfam PF13185 GAF domain 229 367 5.7E-13 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 PANTHER PTHR11347 406 497 7.3E-39 T 16-09-2016 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SUPERFAMILY SSF55781 42 226 9.81E-40 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 SUPERFAMILY SSF55874 476 577 8.77E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Pfam PF07730 Histidine kinase 384 446 3.4E-11 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 PANTHER PTHR11347 22 377 7.3E-39 T 16-09-2016 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 PANTHER PTHR11347:SF114 406 497 7.3E-39 T 16-09-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 Gene3D G3DSA:3.30.450.40 49 206 1.7E-33 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03965 22bfbbdef5ff82ce01788b29900682ae 586 PANTHER PTHR11347:SF114 22 377 7.3E-39 T 16-09-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 PANTHER PTHR30173 1 321 2.2E-186 T 16-09-2016 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 188 9.5E-27 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Pfam PF08281 Sigma-70, region 4 133 186 1.2E-15 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 SUPERFAMILY SSF88946 13 91 1.14E-21 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Gene3D G3DSA:1.10.10.10 129 189 8.8E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 SUPERFAMILY SSF88659 131 188 1.53E-12 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 PANTHER PTHR30173:SF22 1 321 2.2E-186 T 16-09-2016 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Gene3D G3DSA:1.10.1740.10 13 92 2.3E-24 T 16-09-2016 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 5 322 9.4E-153 T 16-09-2016 IPR014305 RNA polymerase sigma-G type, actinobacteria Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 SUPERFAMILY SSF54427 202 318 4.2E-22 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Pfam PF04542 Sigma-70 region 2 14 78 2.1E-20 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Pfam PF12680 SnoaL-like domain 211 305 9.4E-10 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS20720 0378ae48f5fed22f515282ee48912d36 334 Gene3D G3DSA:3.10.450.50 203 319 3.8E-21 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS09335 72115c86a9a193b08599a1ca6b5c259e 284 PANTHER PTHR31310 35 256 3.5E-62 T 16-09-2016 Spa2297_RS09335 72115c86a9a193b08599a1ca6b5c259e 284 Pfam PF14378 PAP2 superfamily 74 255 8.5E-49 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS09335 72115c86a9a193b08599a1ca6b5c259e 284 PANTHER PTHR31310:SF6 35 256 3.5E-62 T 16-09-2016 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 Gene3D G3DSA:3.30.70.940 99 207 1.4E-41 T 16-09-2016 IPR006645 NusG, N-terminal GO:0006355 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 SMART SM00739 233 260 3.5E-4 T 16-09-2016 IPR005824 KOW Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 Pfam PF02357 Transcription termination factor nusG 99 201 8.8E-23 T 16-09-2016 IPR006645 NusG, N-terminal GO:0006355 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 PRINTS PR00338 Transcription termination factor NUSG signature 245 260 4.2E-18 T 16-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 PRINTS PR00338 Transcription termination factor NUSG signature 263 279 4.2E-18 T 16-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 PRINTS PR00338 Transcription termination factor NUSG signature 152 164 4.2E-18 T 16-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 SUPERFAMILY SSF82679 99 205 6.28E-35 T 16-09-2016 IPR006645 NusG, N-terminal GO:0006355 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 97 287 22.584 T 16-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 SUPERFAMILY SSF50104 232 286 4.81E-15 T 16-09-2016 IPR008991 Translation protein SH3-like domain Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 Gene3D G3DSA:2.30.30.30 232 286 1.8E-25 T 16-09-2016 IPR014722 Ribosomal protein L2 domain 2 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 SMART SM00738 97 205 6.1E-44 T 16-09-2016 IPR006645 NusG, N-terminal GO:0006355 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 PANTHER PTHR30265 13 286 4.4E-65 T 16-09-2016 Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 ProSitePatterns PS01014 Transcription termination factor nusG signature. 270 279 - T 16-09-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Spa2297_RS19610 f30af574d762dc84eee9ee6561326291 287 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 100 286 2.9E-54 T 16-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 PANTHER PTHR22572:SF115 1 438 1.2E-198 T 16-09-2016 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 443 2.0E-158 T 16-09-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 Pfam PF00483 Nucleotidyl transferase 6 254 2.5E-14 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 383 418 6.4E-6 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 SUPERFAMILY SSF51161 205 427 2.65E-41 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 Gene3D G3DSA:3.90.550.10 1 239 3.8E-62 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 SUPERFAMILY SSF53448 1 242 2.48E-50 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 Gene3D G3DSA:2.160.10.10 246 427 7.1E-42 T 16-09-2016 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 PANTHER PTHR22572 1 438 1.2E-198 T 16-09-2016 Spa2297_RS13550 90a53321a48355267078cc9a617dbc2b 463 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 441 36.585 T 16-09-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 PANTHER PTHR21581 87 724 6.2E-183 T 16-09-2016 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 480 669 9.2E-33 T 16-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 Gene3D G3DSA:3.40.710.10 476 684 2.6E-50 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 PANTHER PTHR21581:SF3 87 724 6.2E-183 T 16-09-2016 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 486 497 2.3E-11 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 543 560 2.3E-11 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 570 583 2.3E-11 T 16-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spa2297_RS14235 5a5eb187a1c1da0720705ed13f04f146 809 SUPERFAMILY SSF56601 413 677 1.58E-39 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 Gene3D G3DSA:1.20.1250.20 229 408 1.7E-7 T 16-09-2016 Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 Gene3D G3DSA:1.20.1250.20 16 196 2.9E-16 T 16-09-2016 Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 PANTHER PTHR23513:SF6 4 416 3.0E-92 T 16-09-2016 Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 PANTHER PTHR23513 4 416 3.0E-92 T 16-09-2016 Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 Pfam PF07690 Major Facilitator Superfamily 26 364 1.2E-23 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS08340 e4bb3469d792710df49f5769fe168c69 416 SUPERFAMILY SSF103473 16 407 2.22E-35 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 Pfam PF07702 UTRA domain 99 234 2.1E-39 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 SMART SM00866 94 234 2.8E-36 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.9E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.9E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 SUPERFAMILY SSF46785 13 82 1.48E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 6.0E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 PANTHER PTHR11751 122 146 2.3E-20 T 16-09-2016 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 PANTHER PTHR11751 10 76 2.3E-20 T 16-09-2016 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 SMART SM00345 17 74 1.4E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 Gene3D G3DSA:3.40.1410.10 72 239 2.9E-44 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 SUPERFAMILY SSF64288 62 240 2.04E-44 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS30960 84bb171028650961f784d3af80cd7470 287 Gene3D G3DSA:1.10.10.10 13 71 1.3E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 SUPERFAMILY SSF51735 7 143 6.32E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 14 125 1.6E-16 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 Gene3D G3DSA:3.40.50.720 10 179 3.8E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 SUPERFAMILY SSF55347 157 247 5.67E-7 T 16-09-2016 Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 PANTHER PTHR22604:SF14 6 242 1.3E-36 T 16-09-2016 Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 Gene3D G3DSA:3.30.360.10 180 294 6.9E-9 T 16-09-2016 Spa2297_RS01325 6269e17e7686e8f138b91b3736e14ab5 297 PANTHER PTHR22604 6 242 1.3E-36 T 16-09-2016 Spa2297_RS30845 33d5d4145c06f6c57f2711e9f2751832 287 SUPERFAMILY SSF55797 164 284 1.31E-24 T 16-09-2016 IPR014044 CAP domain Spa2297_RS30845 33d5d4145c06f6c57f2711e9f2751832 287 Pfam PF00188 Cysteine-rich secretory protein family 168 283 1.2E-21 T 16-09-2016 IPR014044 CAP domain Spa2297_RS30845 33d5d4145c06f6c57f2711e9f2751832 287 PANTHER PTHR31157 164 286 1.5E-52 T 16-09-2016 Spa2297_RS30845 33d5d4145c06f6c57f2711e9f2751832 287 Gene3D G3DSA:3.40.33.10 164 276 2.0E-12 T 16-09-2016 IPR014044 CAP domain Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 SMART SM00347 28 128 2.1E-15 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 Pfam PF01047 MarR family 35 92 5.5E-14 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 PANTHER PTHR33164 1 152 8.8E-25 T 16-09-2016 Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 SUPERFAMILY SSF46785 13 140 5.33E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03070 4aa3d51c5a4e52935b68e91e8d6bc449 152 Gene3D G3DSA:1.10.10.10 5 139 5.7E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PANTHER PTHR24322:SF25 12 138 3.3E-55 T 16-09-2016 Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 1.2E-42 T 16-09-2016 Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PANTHER PTHR24322:SF25 154 186 3.3E-55 T 16-09-2016 Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 SUPERFAMILY SSF51735 1 259 4.74E-67 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 Gene3D G3DSA:3.40.50.720 2 259 5.6E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PANTHER PTHR24322 12 138 3.3E-55 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PANTHER PTHR24322 154 186 3.3E-55 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.9E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.9E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30260 ef1b812a9845477906d629d1a0f8dc46 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.9E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 1.7E-15 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-15 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 115 124 1.7E-15 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.7E-15 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 1.7E-15 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 Gene3D G3DSA:3.50.50.60 119 327 3.5E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PIRSF PIRSF037495 1 443 9.7E-135 T 16-09-2016 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 Pfam PF04324 BFD-like [2Fe-2S] binding domain 376 425 4.2E-11 T 16-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 SUPERFAMILY SSF51905 1 348 5.91E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.4E-20 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 1.4E-20 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-20 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 1.4E-20 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.4E-20 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 Gene3D G3DSA:3.50.50.60 2 118 3.1E-24 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PANTHER PTHR22912 1 340 2.8E-64 T 16-09-2016 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 307 1.4E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27775 1f93deafaf7169312a8ae4908e56c373 447 PANTHER PTHR22912:SF141 1 340 2.8E-64 T 16-09-2016 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 Gene3D G3DSA:1.10.260.40 5 47 2.2E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 PANTHER PTHR30146 2 334 2.6E-122 T 16-09-2016 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 1.2E-13 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 Gene3D G3DSA:3.40.50.2300 56 170 2.3E-25 T 16-09-2016 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 SMART SM00354 2 69 5.4E-20 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 PANTHER PTHR30146:SF4 2 334 2.6E-122 T 16-09-2016 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 SUPERFAMILY SSF53822 59 333 1.02E-68 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 Pfam PF13377 Periplasmic binding protein-like domain 172 330 1.2E-40 T 16-09-2016 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 SUPERFAMILY SSF47413 5 50 1.13E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28690 60bedf10f78a62fd07843bb94ed50b1a 336 Gene3D G3DSA:3.40.50.2300 171 332 8.1E-53 T 16-09-2016 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 Gene3D G3DSA:1.20.120.530 90 226 1.4E-10 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 SMART SM00345 15 74 5.8E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 SUPERFAMILY SSF46785 6 78 2.2E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 Gene3D G3DSA:1.10.10.10 2 74 4.0E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 6.9E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 4.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 4.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 PANTHER PTHR11751 96 119 1.1E-18 T 16-09-2016 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 PANTHER PTHR11751 10 76 1.1E-18 T 16-09-2016 Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 SMART SM00895 103 225 4.9E-9 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 Pfam PF07729 FCD domain 103 224 1.3E-8 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS00315 164d9bd11e2dbe1c1155873050f350b1 241 SUPERFAMILY SSF48008 102 227 1.33E-9 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 SUPERFAMILY SSF52540 2 224 8.51E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 Pfam PF00005 ABC transporter 17 156 9.3E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 Gene3D G3DSA:3.40.50.300 1 222 6.1E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 PANTHER PTHR24220 3 219 2.1E-121 T 16-09-2016 Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 PANTHER PTHR24220 291 320 2.1E-121 T 16-09-2016 Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 SMART SM00382 26 204 5.9E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 PANTHER PTHR24220:SF523 3 219 2.1E-121 T 16-09-2016 Spa2297_RS22805 56e31bb48e5bbd7d64ecf8fc1070afe6 327 PANTHER PTHR24220:SF523 291 320 2.1E-121 T 16-09-2016 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 PANTHER PTHR11550 1 546 0.0 T 16-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 Gene3D G3DSA:3.40.50.300 5 290 1.1E-130 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 SUPERFAMILY SSF52317 295 546 1.03E-69 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 Hamap MF_01227 CTP synthase [pyrG]. 8 546 50.333 T 16-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 SUPERFAMILY SSF52540 8 272 3.25E-117 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 Pfam PF06418 CTP synthase N-terminus 9 272 5.1E-122 T 16-09-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 Pfam PF00117 Glutamine amidotransferase class-I 307 541 6.2E-47 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 TIGRFAM TIGR00337 PyrG: CTP synthase 7 541 5.6E-228 T 16-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 Spa2297_RS07005 ca2dccbe5366816fd88a6ae793413b5f 549 Gene3D G3DSA:3.40.50.880 294 547 1.2E-84 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS20695 33f36a7dc09c9be0ac2a72eff3ecc733 130 Gene3D G3DSA:3.40.140.10 5 129 9.0E-40 T 16-09-2016 Spa2297_RS20695 33f36a7dc09c9be0ac2a72eff3ecc733 130 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 103 1.3E-9 T 16-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 Spa2297_RS20695 33f36a7dc09c9be0ac2a72eff3ecc733 130 PANTHER PTHR11644 5 128 1.5E-41 T 16-09-2016 Spa2297_RS20695 33f36a7dc09c9be0ac2a72eff3ecc733 130 SUPERFAMILY SSF53927 5 128 1.49E-38 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS20695 33f36a7dc09c9be0ac2a72eff3ecc733 130 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 96 - T 16-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 PANTHER PTHR11986:SF17 1 439 7.7E-203 T 16-09-2016 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 PANTHER PTHR11986 1 439 7.7E-203 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 SUPERFAMILY SSF53383 35 441 8.06E-125 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 Gene3D G3DSA:3.90.1150.10 324 441 2.0E-41 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 Pfam PF00202 Aminotransferase class-III 35 439 2.0E-119 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 Gene3D G3DSA:3.40.640.10 75 323 1.2E-77 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS24055 3fb28c36621932950e5c52c795ea6e56 444 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 441 7.8E-180 T 16-09-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 Gene3D G3DSA:3.40.190.10 121 172 4.5E-6 T 16-09-2016 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 Gene3D G3DSA:1.10.10.10 2 80 3.6E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 PANTHER PTHR30126:SF31 1 301 2.4E-85 T 16-09-2016 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 PANTHER PTHR30126 1 301 2.4E-85 T 16-09-2016 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 Gene3D G3DSA:3.40.190.10 173 261 4.0E-16 T 16-09-2016 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 SUPERFAMILY SSF46785 2 76 8.17E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.5E-21 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 Pfam PF03466 LysR substrate binding domain 90 296 7.5E-25 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS16375 f6e15e8c8bbc51093698ccecc708885b 301 SUPERFAMILY SSF53850 86 297 5.61E-22 T 16-09-2016 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 SUPERFAMILY SSF50129 1 188 5.86E-59 T 16-09-2016 IPR011032 GroES-like Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 136 9.3E-28 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 SUPERFAMILY SSF51735 154 342 2.23E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 PANTHER PTHR11695 313 391 1.0E-134 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 PANTHER PTHR11695 12 297 1.0E-134 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 4.9E-9 T 16-09-2016 IPR027399 Alcohol dehydrogenase GroES-associated Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 Gene3D G3DSA:3.90.180.10 1 179 3.9E-50 T 16-09-2016 IPR011032 GroES-like Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 PANTHER PTHR11695:SF586 313 391 1.0E-134 T 16-09-2016 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 PANTHER PTHR11695:SF586 12 297 1.0E-134 T 16-09-2016 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 Pfam PF00107 Zinc-binding dehydrogenase 188 321 4.3E-9 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS14070 f43e8d84a10ee274e33da0190cf4d230 391 Gene3D G3DSA:3.40.50.720 180 321 5.6E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 Pfam PF05544 Proline racemase 10 333 2.6E-120 T 16-09-2016 IPR008794 Proline racemase family Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 PIRSF PIRSF029792 1 334 5.1E-129 T 16-09-2016 IPR008794 Proline racemase family Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 PANTHER PTHR33442:SF2 1 334 1.5E-155 T 16-09-2016 Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 PANTHER PTHR33442 1 334 1.5E-155 T 16-09-2016 Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 SUPERFAMILY SSF54506 1 332 6.42E-113 T 16-09-2016 Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 Gene3D G3DSA:3.10.310.10 1 155 1.8E-63 T 16-09-2016 Spa2297_RS27785 934be741dde63c35dfc9c89832f15845 334 Gene3D G3DSA:3.10.310.10 156 321 3.2E-57 T 16-09-2016 Spa2297_RS11265 e02253cd0281740ea7acac4e81021e6f 298 Gene3D G3DSA:1.10.3720.10 21 285 9.2E-70 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11265 e02253cd0281740ea7acac4e81021e6f 298 PANTHER PTHR32243:SF12 21 298 1.5E-191 T 16-09-2016 Spa2297_RS11265 e02253cd0281740ea7acac4e81021e6f 298 SUPERFAMILY SSF161098 29 298 2.75E-72 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11265 e02253cd0281740ea7acac4e81021e6f 298 PANTHER PTHR32243 21 298 1.5E-191 T 16-09-2016 Spa2297_RS11265 e02253cd0281740ea7acac4e81021e6f 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 291 9.2E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS33880 f308ccf4f0247a1c7fe5fdb2c0b4609a 204 Gene3D G3DSA:2.40.110.10 10 95 2.1E-7 T 16-09-2016 Spa2297_RS33880 f308ccf4f0247a1c7fe5fdb2c0b4609a 204 SUPERFAMILY SSF56645 10 94 1.44E-10 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 Pfam PF04954 Siderophore-interacting protein 150 266 2.1E-28 T 16-09-2016 IPR007037 Siderophore-interacting protein Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 PANTHER PTHR30157 1 270 3.1E-116 T 16-09-2016 Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 138 4.5E-35 T 16-09-2016 IPR013113 FAD-binding 9, siderophore-interacting Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 Gene3D G3DSA:3.40.50.80 145 270 3.4E-35 T 16-09-2016 Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 PANTHER PTHR30157:SF0 1 270 3.1E-116 T 16-09-2016 Spa2297_RS31190 1a879c65543bf1ac13cc4526378e96de 273 Gene3D G3DSA:2.40.30.10 10 139 4.4E-27 T 16-09-2016 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 68 209 3.0E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Pfam PF00204 DNA gyrase B 273 445 5.0E-62 T 16-09-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 625 683 2.1E-24 T 16-09-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Pfam PF01751 Toprim domain 474 585 2.3E-17 T 16-09-2016 IPR006171 Toprim domain Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Gene3D G3DSA:3.40.50.670 459 676 1.3E-87 T 16-09-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 SUPERFAMILY SSF56719 449 689 3.92E-82 T 16-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 SMART SM00433 70 687 0.0 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 323 336 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 579 591 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 559 576 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 626 642 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 70 85 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 541 557 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 105 118 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 148 162 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR00418 DNA topoisomerase II family signature 475 489 1.9E-67 T 16-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 ProSitePatterns PS00177 DNA topoisomerase II signature. 477 485 - T 16-09-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Gene3D G3DSA:3.30.565.10 41 248 3.6E-86 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 38 694 89.492 T 16-09-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 SUPERFAMILY SSF55874 41 246 5.34E-69 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 230 243 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 297 315 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 215 230 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 663 679 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 367 383 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 415 429 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 525 534 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 429 449 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 647 659 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 41 51 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PRINTS PR01159 DNA gyrase subunit B signature 272 294 1.4E-75 T 16-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 41 694 8.2E-286 T 16-09-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 PANTHER PTHR10169 17 694 1.5E-287 T 16-09-2016 Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 Gene3D G3DSA:3.30.230.10 272 447 3.0E-71 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 SMART SM00387 66 210 6.1E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16595 b5c41146516cca80be4a247b1945f145 694 SUPERFAMILY SSF54211 273 446 8.54E-56 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 PANTHER PTHR24220 13 252 1.6E-110 T 16-09-2016 Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 Gene3D G3DSA:3.40.50.300 9 247 7.9E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 SUPERFAMILY SSF52540 10 251 1.04E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 PANTHER PTHR24220:SF568 13 252 1.6E-110 T 16-09-2016 Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 SMART SM00382 37 252 4.5E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS30155 fd4e6c6b35516babdb34949a9a9008b1 264 Pfam PF00005 ABC transporter 28 180 3.2E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 PANTHER PTHR10357 1 418 2.6E-293 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Pfam PF00128 Alpha amylase, catalytic domain 46 402 1.3E-77 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 SUPERFAMILY SSF51445 371 478 6.01E-135 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 SUPERFAMILY SSF51445 20 344 6.01E-135 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 SMART SM00642 31 433 7.3E-122 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 PANTHER PTHR10357:SF164 1 418 2.6E-293 T 16-09-2016 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 PANTHER PTHR10357 457 562 2.6E-293 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Gene3D G3DSA:2.60.40.1180 481 561 6.2E-15 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 558 5.4E-28 T 16-09-2016 IPR032091 Maltogenic Amylase, C-terminal Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 561 5.5E-300 T 16-09-2016 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Gene3D G3DSA:3.20.20.80 198 427 5.1E-111 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Gene3D G3DSA:3.20.20.80 460 474 5.1E-111 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Gene3D G3DSA:3.20.20.80 25 122 5.1E-111 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 SUPERFAMILY SSF51011 485 561 7.2E-17 T 16-09-2016 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 Gene3D G3DSA:3.90.400.10 123 190 4.7E-25 T 16-09-2016 Spa2297_RS02005 9c925c924f4cc63da452d07434077a86 572 PANTHER PTHR10357:SF164 457 562 2.6E-293 T 16-09-2016 Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 PANTHER PTHR33546 454 668 1.8E-72 T 16-09-2016 Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 PANTHER PTHR33546:SF1 454 668 1.8E-72 T 16-09-2016 Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 SUPERFAMILY SSF50952 218 534 2.22E-13 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 SUPERFAMILY SSF56988 103 210 1.15E-12 T 16-09-2016 Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 SMART SM00758 47 187 8.7E-35 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 Gene3D G3DSA:2.120.10.30 240 544 2.4E-17 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 Gene3D G3DSA:3.90.182.10 86 227 4.5E-27 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS10350 0b8111371c27432066efe92c6a772c4b 671 Pfam PF07691 PA14 domain 48 184 9.6E-22 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 19.567 T 16-09-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 PANTHER PTHR33867:SF1 1 186 1.3E-39 T 16-09-2016 Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 1.9E-33 T 16-09-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 SUPERFAMILY SSF75420 3 85 1.83E-17 T 16-09-2016 IPR028989 Ribosome maturation factor RimP, N-terminal Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 PANTHER PTHR33867 1 186 1.3E-39 T 16-09-2016 Spa2297_RS24150 0d3946a0a0654e96a54a5f3b51cb748e 186 Gene3D G3DSA:3.30.300.70 3 82 2.5E-19 T 16-09-2016 IPR028989 Ribosome maturation factor RimP, N-terminal Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 Gene3D G3DSA:3.40.50.20 36 141 2.7E-29 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 38 395 8.6E-117 T 16-09-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 PANTHER PTHR11609 17 397 2.2E-149 T 16-09-2016 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 37 391 39.903 T 16-09-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 Gene3D G3DSA:3.30.470.20 189 407 6.2E-81 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 Gene3D G3DSA:3.30.1490.20 148 188 1.8E-4 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 SUPERFAMILY SSF56059 134 332 3.71E-58 T 16-09-2016 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 SUPERFAMILY SSF51246 338 406 2.35E-17 T 16-09-2016 IPR011054 Rudiment single hybrid motif Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 SUPERFAMILY SSF52440 36 129 3.31E-26 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 Pfam PF02222 ATP-grasp domain 143 312 6.6E-48 T 16-09-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 Spa2297_RS13260 8657920221bcb267cdaf7e955c3d69ca 411 PANTHER PTHR11609:SF5 17 397 2.2E-149 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 6.9E-25 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 6.3E-6 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 6.3E-6 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 6.3E-6 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 6.3E-6 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 SUPERFAMILY SSF51206 3 142 9.95E-38 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PANTHER PTHR24567:SF30 1 224 2.6E-66 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 SMART SM00100 10 128 3.1E-25 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 SMART SM00419 167 215 2.1E-13 T 16-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 Gene3D G3DSA:1.10.10.10 146 222 6.5E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 SUPERFAMILY SSF46785 145 222 2.93E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 4.3E-17 T 16-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 PANTHER PTHR24567 1 224 2.6E-66 T 16-09-2016 Spa2297_RS17865 10e2e8904f36f5e3dfb0aa120b973256 224 Gene3D G3DSA:2.60.120.10 2 145 1.6E-39 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695:SF294 291 427 6.1E-95 T 16-09-2016 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695:SF294 163 274 6.1E-95 T 16-09-2016 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695:SF294 107 145 6.1E-95 T 16-09-2016 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695:SF294 54 89 6.1E-95 T 16-09-2016 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695 163 274 6.1E-95 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695 54 89 6.1E-95 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 113 189 4.5E-6 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 428 6.5E-192 T 16-09-2016 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 Gene3D G3DSA:3.90.180.10 46 231 9.1E-29 T 16-09-2016 IPR011032 GroES-like Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 SMART SM00829 49 415 1.5E-10 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695 107 145 6.1E-95 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 PANTHER PTHR11695 291 427 6.1E-95 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 SUPERFAMILY SSF50129 51 230 3.72E-27 T 16-09-2016 IPR011032 GroES-like Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 SUPERFAMILY SSF51735 198 392 3.36E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 Gene3D G3DSA:3.40.50.720 232 364 1.2E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26935 05cd3f28d07fb11c1a48c33bd2a17acc 445 Pfam PF00107 Zinc-binding dehydrogenase 236 380 8.1E-38 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 SUPERFAMILY SSF50249 200 339 1.11E-15 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 PANTHER PTHR10459:SF51 288 351 5.4E-171 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 PANTHER PTHR10459:SF51 1 262 5.4E-171 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 SUPERFAMILY SSF56091 6 197 1.6E-42 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 16-09-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 Reactome: REACT_216 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 PANTHER PTHR10459 1 262 5.4E-171 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 PANTHER PTHR10459 288 351 5.4E-171 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Pfam PF01068 ATP dependent DNA ligase domain 11 197 3.0E-40 T 16-09-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Gene3D G3DSA:3.30.470.30 32 149 1.2E-27 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Gene3D G3DSA:3.30.1490.70 3 31 3.3E-11 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Gene3D G3DSA:3.30.1490.70 156 198 3.3E-11 T 16-09-2016 Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Gene3D G3DSA:2.40.50.140 200 336 1.7E-14 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS27915 2cced00ee2ac1aec8dde1de38df66bd6 355 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 330 5.5E-16 T 16-09-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PIRSF PIRSF000156 10 910 0.0 T 16-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624:SF67 809 892 0.0 T 16-09-2016 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 SUPERFAMILY SSF52518 70 482 1.12E-125 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 SUPERFAMILY SSF52518 488 722 1.91E-84 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624:SF67 377 466 0.0 T 16-09-2016 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624:SF67 87 308 0.0 T 16-09-2016 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 Gene3D G3DSA:3.40.50.920 730 902 5.4E-69 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624 496 548 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 906 0.0 T 16-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 1.2E-5 T 16-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624 809 892 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624 377 466 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624 87 308 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 Gene3D G3DSA:3.40.50.970 70 483 8.6E-147 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 SUPERFAMILY SSF52922 725 900 5.89E-54 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 Gene3D G3DSA:3.40.50.970 488 726 9.4E-109 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624:SF67 569 790 0.0 T 16-09-2016 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624:SF67 496 548 0.0 T 16-09-2016 Spa2297_RS09975 9c5d193f93fe0803601bd2340c45845b 915 PANTHER PTHR11624 569 790 0.0 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 PIRSF PIRSF036628 1 281 3.4E-102 T 16-09-2016 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30|UniPathway: UPA00076 Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 Gene3D G3DSA:2.60.120.10 17 122 1.5E-27 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 Gene3D G3DSA:2.60.120.10 123 281 1.2E-64 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 SUPERFAMILY SSF51182 16 259 1.4E-62 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 PANTHER PTHR39193:SF1 1 289 5.1E-130 T 16-09-2016 Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 PANTHER PTHR39193 1 289 5.1E-130 T 16-09-2016 Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 Pfam PF04962 KduI/IolB family 10 275 5.6E-87 T 16-09-2016 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 Spa2297_RS28465 feb57d4086cbdfb842fbc9fea7ce3ae6 298 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 19 276 1.1E-81 T 16-09-2016 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30|UniPathway: UPA00076 Spa2297_RS05570 8cdbdc53e44e050bf50e9fe2fcbd9343 107 Gene3D G3DSA:1.10.8.50 50 104 5.4E-14 T 16-09-2016 Spa2297_RS05570 8cdbdc53e44e050bf50e9fe2fcbd9343 107 SUPERFAMILY SSF46946 56 103 1.18E-7 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS04025 8db0c547419d68d3c35c0c5aa75edcb3 362 PANTHER PTHR30572:SF11 1 361 1.8E-32 T 16-09-2016 Spa2297_RS04025 8db0c547419d68d3c35c0c5aa75edcb3 362 Pfam PF02687 FtsX-like permease family 246 354 5.9E-12 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS04025 8db0c547419d68d3c35c0c5aa75edcb3 362 PANTHER PTHR30572 1 361 1.8E-32 T 16-09-2016 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 61 69 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 PANTHER PTHR11908:SF66 21 157 1.2E-38 T 16-09-2016 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 SUPERFAMILY SSF47741 106 172 1.7E-30 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 PANTHER PTHR11908 21 157 1.2E-38 T 16-09-2016 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 Gene3D G3DSA:3.10.20.30 24 96 4.2E-30 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 Pfam PF01799 [2Fe-2S] binding domain 95 167 3.1E-31 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 SUPERFAMILY SSF54292 24 109 3.67E-26 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 Gene3D G3DSA:1.10.150.120 97 172 1.5E-32 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS29275 919635d356838c5905585baadbb4d0e9 174 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 29 84 4.7E-8 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 PANTHER PTHR24567:SF32 1 133 2.4E-29 T 16-09-2016 Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 Pfam PF00027 Cyclic nucleotide-binding domain 26 113 1.0E-11 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 SMART SM00100 7 128 0.0053 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 SUPERFAMILY SSF51206 5 127 1.57E-22 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 Gene3D G3DSA:2.60.120.10 5 126 4.5E-17 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS03925 d50cde6d00099bd92c6d3daabd65ae65 152 PANTHER PTHR24567 1 133 2.4E-29 T 16-09-2016 Spa2297_RS31475 19b0d548ecb94e80abd6593970fbe945 127 PANTHER PTHR33204 6 122 5.6E-40 T 16-09-2016 Spa2297_RS31475 19b0d548ecb94e80abd6593970fbe945 127 PANTHER PTHR33204:SF8 6 122 5.6E-40 T 16-09-2016 Spa2297_RS31475 19b0d548ecb94e80abd6593970fbe945 127 Gene3D G3DSA:1.10.10.10 12 123 5.8E-40 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31475 19b0d548ecb94e80abd6593970fbe945 127 Pfam PF01638 HxlR-like helix-turn-helix 30 117 4.6E-30 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS31475 19b0d548ecb94e80abd6593970fbe945 127 SUPERFAMILY SSF46785 24 122 3.61E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 Pfam PF00652 Ricin-type beta-trefoil lectin domain 296 441 2.0E-22 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 PANTHER PTHR11675 291 449 2.8E-92 T 16-09-2016 Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 Gene3D G3DSA:2.80.10.50 293 443 1.7E-23 T 16-09-2016 Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 SUPERFAMILY SSF50370 290 445 2.23E-26 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 PANTHER PTHR11675:SF45 291 449 2.8E-92 T 16-09-2016 Spa2297_RS14970 72bd34d0423a3da821816bb0a840aa99 449 SMART SM00458 292 444 4.2E-9 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 SUPERFAMILY SSF49472 5 133 1.02E-28 T 16-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 PANTHER PTHR10395:SF7 8 78 5.6E-36 T 16-09-2016 Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 PANTHER PTHR10395:SF7 99 133 5.6E-36 T 16-09-2016 Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 7 133 3.8E-31 T 16-09-2016 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 Pfam PF00576 HIUase/Transthyretin family 9 132 1.0E-35 T 16-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 PANTHER PTHR10395 8 78 5.6E-36 T 16-09-2016 Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 PANTHER PTHR10395 99 133 5.6E-36 T 16-09-2016 Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 Gene3D G3DSA:2.60.40.180 6 133 1.2E-35 T 16-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Spa2297_RS26325 4dfaa07cdc67f607202952a41f8ed93d 133 ProSitePatterns PS00768 Transthyretin signature 1. 12 27 - T 16-09-2016 IPR023418 Transthyretin, thyroxine binding site Spa2297_RS04570 33e2c1bf8d9ab9337f2a784189715c0e 260 PANTHER PTHR30383 1 258 1.0E-138 T 16-09-2016 Spa2297_RS04570 33e2c1bf8d9ab9337f2a784189715c0e 260 PANTHER PTHR30383:SF8 1 258 1.0E-138 T 16-09-2016 Spa2297_RS04570 33e2c1bf8d9ab9337f2a784189715c0e 260 SUPERFAMILY SSF52266 7 192 2.14E-34 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS04570 33e2c1bf8d9ab9337f2a784189715c0e 260 Gene3D G3DSA:3.40.50.1110 8 194 4.1E-33 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS04570 33e2c1bf8d9ab9337f2a784189715c0e 260 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 183 5.1E-21 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 SMART SM00346 15 105 1.1E-6 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 SUPERFAMILY SSF55781 86 256 7.85E-35 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 Gene3D G3DSA:3.30.450.40 91 256 9.6E-39 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 PANTHER PTHR30136:SF12 1 244 2.9E-108 T 16-09-2016 Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 PANTHER PTHR30136 1 244 2.9E-108 T 16-09-2016 Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 Pfam PF09339 IclR helix-turn-helix domain 17 67 2.6E-7 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 Pfam PF01614 Bacterial transcriptional regulator 132 250 4.1E-20 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 SUPERFAMILY SSF46785 17 88 2.72E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32135 9d405aa035400d9b146e3071900ad378 260 Gene3D G3DSA:1.10.10.10 15 86 1.9E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10990 0464a3bea1f4a003e51fa9030a944e3e 205 PANTHER PTHR34309 1 153 3.4E-69 T 16-09-2016 Spa2297_RS10990 0464a3bea1f4a003e51fa9030a944e3e 205 PANTHER PTHR34309:SF2 1 153 3.4E-69 T 16-09-2016 Spa2297_RS10990 0464a3bea1f4a003e51fa9030a944e3e 205 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 135 1.2E-5 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS10990 0464a3bea1f4a003e51fa9030a944e3e 205 SUPERFAMILY SSF54593 3 143 2.34E-17 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS10990 0464a3bea1f4a003e51fa9030a944e3e 205 Gene3D G3DSA:3.10.180.10 8 135 9.7E-18 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 Gene3D G3DSA:1.20.1250.20 39 224 6.8E-34 T 16-09-2016 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 Gene3D G3DSA:1.20.1250.20 253 436 1.2E-23 T 16-09-2016 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 PANTHER PTHR23508 1 438 1.3E-216 T 16-09-2016 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 Pfam PF07690 Major Facilitator Superfamily 46 396 1.2E-45 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 PANTHER PTHR23508:SF18 1 438 1.3E-216 T 16-09-2016 Spa2297_RS05250 5e54c33bb4bfb8b0aed71317c7ae1652 439 SUPERFAMILY SSF103473 24 438 1.83E-79 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Pfam PF04545 Sigma-70, region 4 207 256 1.4E-16 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 258 1.1E-82 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 SUPERFAMILY SSF88946 31 111 7.33E-27 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Gene3D G3DSA:1.10.601.10 33 108 4.1E-20 T 16-09-2016 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 PANTHER PTHR30385 12 261 1.9E-97 T 16-09-2016 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 257 1.3E-32 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 SUPERFAMILY SSF88659 114 189 2.53E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Gene3D G3DSA:1.10.10.10 110 164 7.8E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Pfam PF04539 Sigma-70 region 3 121 174 2.4E-8 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 PRINTS PR00046 Major sigma-70 factor signature 228 243 5.2E-7 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 PRINTS PR00046 Major sigma-70 factor signature 211 223 5.2E-7 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 PRINTS PR00046 Major sigma-70 factor signature 65 78 5.2E-7 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 SUPERFAMILY SSF88659 185 258 6.35E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Pfam PF04542 Sigma-70 region 2 41 110 5.9E-19 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 PANTHER PTHR30385:SF4 12 261 1.9E-97 T 16-09-2016 Spa2297_RS01970 9ac74a0a0b3cb25e627560c7a16467d1 263 Gene3D G3DSA:1.10.10.10 201 257 4.9E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.1E-10 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PANTHER PTHR33164:SF4 2 163 1.2E-31 T 16-09-2016 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 PANTHER PTHR33164 2 163 1.2E-31 T 16-09-2016 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 SUPERFAMILY SSF46785 11 160 3.62E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 SMART SM00347 43 146 8.6E-24 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 Pfam PF01047 MarR family 54 111 2.8E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 Gene3D G3DSA:1.10.10.10 9 161 1.6E-37 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13600 ad4ff63d0c9f2cf4b6aa89397c799f7e 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 PIRSF PIRSF005096 4 332 1.9E-84 T 16-09-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 PANTHER PTHR10091:SF0 1 332 3.3E-82 T 16-09-2016 Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 Pfam PF01263 Aldose 1-epimerase 23 326 8.8E-58 T 16-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 PANTHER PTHR10091 1 332 3.3E-82 T 16-09-2016 Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 SUPERFAMILY SSF74650 20 329 1.38E-79 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS02945 e8b3c25a983d0702a2ad80052541564a 332 Gene3D G3DSA:2.70.98.10 19 329 7.6E-83 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 Gene3D G3DSA:3.60.15.10 5 300 1.5E-70 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 SUPERFAMILY SSF56281 5 296 8.26E-60 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 30.442 T 16-09-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 Pfam PF12706 Beta-lactamase superfamily domain 34 263 1.4E-16 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 PANTHER PTHR12553 5 152 9.3E-71 T 16-09-2016 Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 PANTHER PTHR12553 168 300 9.3E-71 T 16-09-2016 Spa2297_RS10725 009a6117c9773089a87d2997456502ac 301 SMART SM00849 21 211 0.0067 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Gene3D G3DSA:1.20.200.10 133 397 9.8E-96 T 16-09-2016 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 461 82.344 T 16-09-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Pfam PF10415 Fumarase C C-terminus 402 460 6.1E-21 T 16-09-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 ProSitePatterns PS00163 Fumarate lyases signature. 311 320 - T 16-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00149 Fumarate lyase superfamily signature 128 146 2.6E-33 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 2.6E-33 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00149 Fumarate lyase superfamily signature 174 192 2.6E-33 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00149 Fumarate lyase superfamily signature 311 327 2.6E-33 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PANTHER PTHR11444:SF1 1 461 1.1E-229 T 16-09-2016 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Pfam PF00206 Lyase 12 336 4.0E-103 T 16-09-2016 IPR022761 Fumarate lyase, N-terminal Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Gene3D G3DSA:1.10.275.10 3 132 2.7E-53 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 SUPERFAMILY SSF48557 3 459 4.08E-146 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PANTHER PTHR11444 1 461 1.1E-229 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00145 Argininosuccinate lyase family signature 169 189 3.5E-6 T 16-09-2016 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 PRINTS PR00145 Argininosuccinate lyase family signature 311 327 3.5E-6 T 16-09-2016 Spa2297_RS21350 8b30eb1b049a67853498174151888cc7 461 Gene3D G3DSA:1.10.40.30 402 461 2.4E-21 T 16-09-2016 Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 Pfam PF00672 HAMP domain 39 106 6.5E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 PANTHER PTHR24421:SF10 92 316 8.2E-56 T 16-09-2016 Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 Gene3D G3DSA:3.30.565.10 222 315 4.2E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 SUPERFAMILY SSF55874 187 311 4.58E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 SMART SM00387 224 314 4.4E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 PANTHER PTHR24421 92 316 8.2E-56 T 16-09-2016 Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 Pfam PF07730 Histidine kinase 122 186 1.7E-17 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS26130 fc1e398d57eb9a42d87e49f2dea5614e 317 SMART SM00304 57 109 1.1E-8 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS10130 a593d0c13e9a957860eb14b9d108ea07 414 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 402 2.6E-45 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS10130 a593d0c13e9a957860eb14b9d108ea07 414 PANTHER PTHR32196:SF21 9 199 1.4E-144 T 16-09-2016 Spa2297_RS10130 a593d0c13e9a957860eb14b9d108ea07 414 PANTHER PTHR32196 258 411 1.4E-144 T 16-09-2016 Spa2297_RS10130 a593d0c13e9a957860eb14b9d108ea07 414 PANTHER PTHR32196 9 199 1.4E-144 T 16-09-2016 Spa2297_RS10130 a593d0c13e9a957860eb14b9d108ea07 414 PANTHER PTHR32196:SF21 258 411 1.4E-144 T 16-09-2016 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 PANTHER PTHR13833:SF38 5 435 4.7E-133 T 16-09-2016 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 SUPERFAMILY SSF101898 163 466 3.66E-34 T 16-09-2016 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 Gene3D G3DSA:2.120.10.30 173 466 6.0E-45 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 Gene3D G3DSA:3.40.30.10 20 147 4.7E-37 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 Pfam PF01436 NHL repeat 397 424 3.8E-5 T 16-09-2016 IPR001258 NHL repeat GO:0005515 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 Pfam PF01436 NHL repeat 229 256 5.4E-5 T 16-09-2016 IPR001258 NHL repeat GO:0005515 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 SUPERFAMILY SSF52833 20 147 8.01E-28 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 PANTHER PTHR13833 5 435 4.7E-133 T 16-09-2016 Spa2297_RS29255 883262d95e057990f3cab135c228d693 600 Pfam PF00578 AhpC/TSA family 20 129 1.2E-10 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 SUPERFAMILY SSF46785 5 79 8.33E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 Pfam PF09339 IclR helix-turn-helix domain 7 54 1.2E-12 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 SMART SM00346 5 96 1.4E-15 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 Pfam PF01614 Bacterial transcriptional regulator 124 248 4.4E-34 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 PANTHER PTHR30136:SF2 3 255 1.4E-107 T 16-09-2016 Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 Gene3D G3DSA:3.30.450.40 79 254 1.5E-55 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 PANTHER PTHR30136 3 255 1.4E-107 T 16-09-2016 Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 SUPERFAMILY SSF55781 71 254 2.94E-51 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS10290 56cdfcc2cea813e6d250a46596ce60a7 257 Gene3D G3DSA:1.10.10.10 5 69 4.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 Pfam PF02566 OsmC-like protein 43 138 3.4E-18 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 138 1.3E-54 T 16-09-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 PANTHER PTHR33797 3 138 2.9E-69 T 16-09-2016 Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 Gene3D G3DSA:2.20.25.10 6 49 1.4E-19 T 16-09-2016 Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 PANTHER PTHR33797:SF2 3 138 2.9E-69 T 16-09-2016 Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 Gene3D G3DSA:3.30.300.20 50 138 2.1E-36 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS10085 928fc142d5f798ca271fbde475572a1b 139 SUPERFAMILY SSF82784 4 138 1.18E-43 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 PANTHER PTHR11814 29 647 2.0E-225 T 16-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 PANTHER PTHR11814:SF123 29 647 2.0E-225 T 16-09-2016 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 SMART SM00947 620 813 1.4E-51 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 Gene3D G3DSA:3.40.1050.10 594 819 3.3E-75 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 Pfam PF00484 Carbonic anhydrase 628 807 8.4E-42 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 Pfam PF00916 Sulfate permease family 36 401 2.0E-52 T 16-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 Gene3D G3DSA:3.30.750.24 434 511 6.9E-4 T 16-09-2016 IPR002645 STAS domain Spa2297_RS17905 e9299e1a19ff5eedd0837833defd7736 831 SUPERFAMILY SSF53056 594 815 3.14E-47 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 SUPERFAMILY SSF52343 108 255 2.1E-36 T 16-09-2016 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Gene3D G3DSA:3.40.50.80 109 250 9.8E-40 T 16-09-2016 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 163 6.2E-9 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 148 6.2E-9 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 71 78 6.2E-9 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00410 Phenol hydroxylase reductase family signature 225 233 6.2E-9 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Gene3D G3DSA:2.40.30.10 18 108 2.8E-22 T 16-09-2016 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Pfam PF00175 Oxidoreductase NAD-binding domain 130 239 1.5E-19 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 SUPERFAMILY SSF63380 16 120 2.51E-22 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 315 323 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PANTHER PTHR19370 7 257 9.8E-59 T 16-09-2016 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Pfam PF00970 Oxidoreductase FAD-binding domain 23 118 2.4E-11 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 283 357 5.9E-14 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 Gene3D G3DSA:3.10.20.30 251 366 1.9E-28 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 20 367 3.3E-166 T 16-09-2016 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00930 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 71 78 3.3E-6 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 163 3.3E-6 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 166 177 3.3E-6 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 129 148 3.3E-6 T 16-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spa2297_RS01360 ebfd1cc5406c42b5245e3dc5ff088c14 368 SUPERFAMILY SSF54292 247 366 4.98E-26 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS26680 22c4236005b047d3c30d9d6221bbf7b5 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 6 87 2.0E-8 T 16-09-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26680 22c4236005b047d3c30d9d6221bbf7b5 130 Gene3D G3DSA:3.90.470.20 2 118 3.0E-25 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26680 22c4236005b047d3c30d9d6221bbf7b5 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 102 1.1E-15 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26680 22c4236005b047d3c30d9d6221bbf7b5 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 118 9.2E-17 T 16-09-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS26680 22c4236005b047d3c30d9d6221bbf7b5 130 SUPERFAMILY SSF56214 3 118 3.92E-19 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 Gene3D G3DSA:1.20.1250.20 18 196 2.4E-30 T 16-09-2016 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 SUPERFAMILY SSF103473 17 400 4.05E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 PANTHER PTHR23508 18 401 4.7E-201 T 16-09-2016 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 Pfam PF07690 Major Facilitator Superfamily 24 305 1.1E-36 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 Gene3D G3DSA:1.20.1250.20 225 395 2.6E-19 T 16-09-2016 Spa2297_RS01565 1be1f4c5fe30463ecc629d6326072010 414 PANTHER PTHR23508:SF15 18 401 4.7E-201 T 16-09-2016 Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 PANTHER PTHR11620 45 134 1.2E-33 T 16-09-2016 Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 SUPERFAMILY SSF54189 44 136 1.01E-31 T 16-09-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 ProSitePatterns PS00050 Ribosomal protein L23 signature. 119 134 - T 16-09-2016 IPR001014 Ribosomal protein L23/L25, conserved site Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 47 136 21.952 T 16-09-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 Gene3D G3DSA:3.30.70.330 45 135 1.4E-35 T 16-09-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 Spa2297_RS19805 dd2a6dffd7935a37e0d8d2c659bf5497 139 Pfam PF00276 Ribosomal protein L23 48 133 2.6E-31 T 16-09-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS09665 a23b4dd6d27c146a463f3490d82c264b 216 Pfam PF13578 Methyltransferase domain 43 171 4.7E-23 T 16-09-2016 Spa2297_RS09665 a23b4dd6d27c146a463f3490d82c264b 216 Gene3D G3DSA:3.40.50.150 42 174 1.1E-11 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09665 a23b4dd6d27c146a463f3490d82c264b 216 SUPERFAMILY SSF53335 41 192 3.96E-13 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 Gene3D G3DSA:3.30.420.40 4 232 5.6E-58 T 16-09-2016 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 SUPERFAMILY SSF53067 236 469 2.1E-55 T 16-09-2016 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 PIRSF PIRSF000538 2 475 4.4E-109 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 Gene3D G3DSA:3.30.420.40 237 473 8.8E-65 T 16-09-2016 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 SUPERFAMILY SSF53067 5 235 1.92E-57 T 16-09-2016 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 242 428 8.6E-43 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 232 2.4E-43 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 PANTHER PTHR10196:SF9 1 472 4.4E-147 T 16-09-2016 Spa2297_RS28630 aab3be0448ce21d14c6f2391601a4ce6 479 PANTHER PTHR10196 1 472 4.4E-147 T 16-09-2016 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 457 468 1.8E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 490 502 1.8E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 1.8E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Gene3D G3DSA:3.50.50.60 338 395 3.5E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Gene3D G3DSA:3.50.50.60 169 249 3.5E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Gene3D G3DSA:3.50.50.60 22 121 3.5E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Pfam PF01266 FAD dependent oxidoreductase 32 378 1.0E-46 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Pfam PF00355 Rieske [2Fe-2S] domain 425 503 2.4E-18 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 SUPERFAMILY SSF51905 31 251 6.91E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 SUPERFAMILY SSF51905 338 396 6.91E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 PANTHER PTHR13847 1 458 4.5E-52 T 16-09-2016 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 SUPERFAMILY SSF50022 423 504 4.45E-28 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 PANTHER PTHR13847:SF196 1 458 4.5E-52 T 16-09-2016 Spa2297_RS31875 88db6b4c3fbbcae4c2f6de670f290624 507 Gene3D G3DSA:2.102.10.10 412 504 1.1E-30 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 Gene3D G3DSA:2.160.20.10 27 358 1.0E-80 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 SUPERFAMILY SSF49785 400 516 9.04E-6 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 SUPERFAMILY SSF51126 35 359 3.89E-72 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 SMART SM00656 76 288 8.9E-18 T 16-09-2016 IPR002022 Pectate lyase/Amb allergen Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 PANTHER PTHR31683 105 300 5.8E-75 T 16-09-2016 Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 PANTHER PTHR31683 31 88 5.8E-75 T 16-09-2016 Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 PANTHER PTHR31683:SF6 105 300 5.8E-75 T 16-09-2016 Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 PANTHER PTHR31683:SF6 31 88 5.8E-75 T 16-09-2016 Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 Gene3D G3DSA:2.60.120.260 396 470 4.4E-6 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS12045 826a94438c3439fb9b50cd6b9e77a90a 520 Pfam PF00544 Pectate lyase 81 282 5.5E-33 T 16-09-2016 IPR002022 Pectate lyase/Amb allergen Spa2297_RS26095 a8afd9869323689f15626a7ba03271a7 139 SUPERFAMILY SSF55874 44 132 9.25E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26095 a8afd9869323689f15626a7ba03271a7 139 Gene3D G3DSA:3.30.565.10 25 134 2.5E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26095 a8afd9869323689f15626a7ba03271a7 139 Pfam PF13581 Histidine kinase-like ATPase domain 23 131 2.1E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 PANTHER PTHR10907:SF33 108 281 3.6E-34 T 16-09-2016 Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 SUPERFAMILY SSF53474 114 372 9.56E-31 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 Pfam PF00756 Putative esterase 133 364 4.3E-15 T 16-09-2016 IPR000801 Putative esterase Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 Gene3D G3DSA:3.40.50.1820 114 371 1.4E-42 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 PANTHER PTHR10907:SF33 324 341 3.6E-34 T 16-09-2016 Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 PANTHER PTHR10907 108 281 3.6E-34 T 16-09-2016 Spa2297_RS18220 84e78f2f6ad12b7a849e6580921b0412 376 PANTHER PTHR10907 324 341 3.6E-34 T 16-09-2016 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 SUPERFAMILY SSF46689 17 81 7.09E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 2.3E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 Gene3D G3DSA:1.10.357.10 71 199 3.4E-24 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 PANTHER PTHR30055:SF6 11 202 3.3E-85 T 16-09-2016 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 Gene3D G3DSA:1.10.10.60 16 70 1.2E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 SUPERFAMILY SSF48498 89 198 5.48E-16 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 195 2.3E-25 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS27855 9097ad8a6e4f70f20ad8a6a72e26bc8f 203 PANTHER PTHR30055 11 202 3.3E-85 T 16-09-2016 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Gene3D G3DSA:3.40.50.10490 12 100 4.3E-130 T 16-09-2016 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Gene3D G3DSA:3.40.50.10490 297 506 4.3E-130 T 16-09-2016 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PANTHER PTHR11469 1 551 0.0 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Pfam PF00342 Phosphoglucose isomerase 54 541 1.7E-216 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Gene3D G3DSA:1.10.1390.10 507 548 5.2E-20 T 16-09-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 4.5E-53 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Gene3D G3DSA:3.40.50.10490 101 294 2.1E-82 T 16-09-2016 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 40.957 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 SUPERFAMILY SSF53697 9 548 1.47E-204 T 16-09-2016 Spa2297_RS07825 9f13379d8113463da9d34287d231b313 551 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 16-09-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 SUPERFAMILY SSF53790 8 197 2.09E-31 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 Gene3D G3DSA:3.40.1010.10 5 103 3.7E-16 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 PIRSF PIRSF036428 1 400 1.6E-87 T 16-09-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 2.6E-36 T 16-09-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 Gene3D G3DSA:3.40.50.150 248 372 1.4E-16 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 PANTHER PTHR14741 246 374 6.5E-27 T 16-09-2016 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 PANTHER PTHR14741:SF34 246 374 6.5E-27 T 16-09-2016 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 Gene3D G3DSA:3.30.950.10 104 198 6.9E-17 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 183 2.9E-18 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS05955 ed0d5e3378f9a7d5a8067b0e04fa294a 406 SUPERFAMILY SSF53335 243 373 2.87E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 79 330 5.2E-45 T 16-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 Gene3D G3DSA:1.10.40.50 279 340 2.4E-21 T 16-09-2016 Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 PANTHER PTHR32120 1 367 2.8E-165 T 16-09-2016 Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 SUPERFAMILY SSF52540 116 335 3.92E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 Gene3D G3DSA:3.40.50.300 116 271 2.4E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 PANTHER PTHR32120:SF8 1 367 2.8E-165 T 16-09-2016 Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 Pfam PF03193 Protein of unknown function, DUF258 98 274 6.1E-46 T 16-09-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 Spa2297_RS26060 049fa45541e9c545d9feb096d04bce80 372 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 40 337 31.644 T 16-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Gene3D G3DSA:2.40.10.10 281 392 2.8E-20 T 16-09-2016 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Gene3D G3DSA:2.40.10.10 195 280 5.9E-11 T 16-09-2016 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 226 231 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 PIRSF PIRSF001134 1 399 1.8E-64 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 2.0E-13 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 332 355 2.0E-13 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 356 370 2.0E-13 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Pfam PF02983 Alpha-lytic protease prodomain 119 174 3.3E-11 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 341 352 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 SUPERFAMILY SSF50494 196 396 6.69E-26 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Pfam PF00089 Trypsin 221 381 9.8E-6 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Gene3D G3DSA:3.30.300.50 118 187 2.7E-17 T 16-09-2016 Spa2297_RS26815 bee1980f1b144aacd9f5dbbb8cb3a70c 399 Gene3D G3DSA:3.30.300.50 39 115 8.4E-7 T 16-09-2016 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 PANTHER PTHR26402:SF151 32 242 8.7E-55 T 16-09-2016 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 ProSitePatterns PS00622 LuxR-type HTH domain signature. 202 229 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 SMART SM00448 32 151 4.3E-17 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 202 1.1E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 218 230 1.1E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 218 1.1E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 SUPERFAMILY SSF52172 31 169 1.71E-21 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 Pfam PF00196 Bacterial regulatory proteins, luxR family 187 242 8.0E-20 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 SUPERFAMILY SSF46894 178 247 3.4E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 Gene3D G3DSA:1.10.10.10 155 248 2.6E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 SMART SM00421 185 242 2.1E-25 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 Pfam PF00072 Response regulator receiver domain 34 151 9.6E-16 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 Gene3D G3DSA:3.40.50.2300 29 154 1.1E-23 T 16-09-2016 Spa2297_RS20220 9e32374e761900621558446f7db03eb3 248 PANTHER PTHR26402 32 242 8.7E-55 T 16-09-2016 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 PANTHER PTHR21021 367 670 2.6E-59 T 16-09-2016 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Pfam PF08448 PAS fold 121 231 2.5E-19 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SUPERFAMILY SSF55781 298 417 1.88E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 PANTHER PTHR21021:SF19 367 670 2.6E-59 T 16-09-2016 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SUPERFAMILY SSF55785 7 97 9.03E-8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Gene3D G3DSA:3.30.450.20 117 230 7.2E-17 T 16-09-2016 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Pfam PF13426 PAS domain 16 95 0.76 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 470 661 4.4E-52 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SUPERFAMILY SSF81606 457 660 2.22E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SMART SM00065 235 423 4.6E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SMART SM00091 1 69 2.6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SMART SM00091 115 181 0.0025 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Pfam PF13581 Histidine kinase-like ATPase domain 674 782 1.4E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SMART SM00331 441 661 7.3E-32 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Pfam PF01590 GAF domain 257 413 6.5E-10 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SUPERFAMILY SSF55785 117 222 4.71E-14 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Gene3D G3DSA:3.30.450.40 241 421 1.6E-34 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 SUPERFAMILY SSF55874 702 778 1.41E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 118 237 8.7E-12 T 16-09-2016 IPR000014 PAS domain Spa2297_RS29885 1ba4baf479d8d28784e103c3c27cc2bc 792 Gene3D G3DSA:3.30.450.20 7 102 1.2E-4 T 16-09-2016 Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 Gene3D G3DSA:3.40.50.2000 171 343 3.2E-27 T 16-09-2016 Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 PANTHER PTHR12526 1 369 1.3E-70 T 16-09-2016 Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 Pfam PF13439 Glycosyltransferase Family 4 14 181 5.7E-25 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 Pfam PF00534 Glycosyl transferases group 1 189 344 4.5E-24 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 SUPERFAMILY SSF53756 1 366 7.85E-78 T 16-09-2016 Spa2297_RS05285 86b6608016ee772dadab962ed52f382f 375 PANTHER PTHR12526:SF363 1 369 1.3E-70 T 16-09-2016 Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PANTHER PTHR24322:SF570 149 181 3.2E-59 T 16-09-2016 Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PANTHER PTHR24322:SF570 13 132 3.2E-59 T 16-09-2016 Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.4E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.4E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.4E-6 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PANTHER PTHR24322 149 181 3.2E-59 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PANTHER PTHR24322 13 132 3.2E-59 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 4.5E-37 T 16-09-2016 Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 SUPERFAMILY SSF51735 7 253 9.13E-57 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00295 dfa90a0313ba0cbfdfffa485083103f0 257 Gene3D G3DSA:3.40.50.720 5 253 1.0E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11375 46708743a7982ba769b3f6365daa72a4 467 Pfam PF05506 Domain of unknown function (DUF756) 334 395 1.4E-9 T 16-09-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 Spa2297_RS11375 46708743a7982ba769b3f6365daa72a4 467 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 125 173 1.5E-16 T 16-09-2016 IPR023849 Uncharacterised domain CHP03934, TQXA Spa2297_RS30505 7e5fc19939fd344331fab424e3e962be 247 PANTHER PTHR33973 8 238 5.1E-51 T 16-09-2016 Spa2297_RS30505 7e5fc19939fd344331fab424e3e962be 247 Pfam PF07103 Protein of unknown function (DUF1365) 11 239 6.7E-61 T 16-09-2016 IPR010775 Protein of unknown function DUF1365 Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 SUPERFAMILY SSF51182 12 447 1.69E-160 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 13 447 71.466 T 16-09-2016 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 12 445 5.2E-219 T 16-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 PANTHER PTHR11056 1 449 5.7E-246 T 16-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 Pfam PF04209 homogentisate 1,2-dioxygenase 13 445 2.8E-212 T 16-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 Gene3D G3DSA:2.60.120.10 209 234 2.3E-7 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS06735 76b862a09b47d9903b0a8277c17532ce 449 Gene3D G3DSA:2.60.120.10 261 415 1.1E-61 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 PANTHER PTHR33164 1 169 1.4E-105 T 16-09-2016 Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 PANTHER PTHR33164:SF7 1 169 1.4E-105 T 16-09-2016 Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 Pfam PF12802 MarR family 54 114 2.1E-11 T 16-09-2016 Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 SMART SM00347 48 149 1.2E-21 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 SUPERFAMILY SSF46785 26 159 6.82E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22885 c1f5e0b0be0cbd6f7d64923dd0f861b8 169 Gene3D G3DSA:1.10.10.10 28 159 3.0E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 PANTHER PTHR32282 553 819 0.0 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SMART SM00382 29 441 5.6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SMART SM00382 506 785 0.0011 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 PANTHER PTHR32282:SF4 553 819 0.0 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 ProSitePatterns PS00211 ABC transporters family signature. 364 378 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SUPERFAMILY SSF52540 313 446 1.05E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SUPERFAMILY SSF52540 10 58 1.05E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 PANTHER PTHR32282 6 537 0.0 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Pfam PF00005 ABC transporter 497 740 1.3E-8 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:1.20.1580.10 99 159 2.0E-31 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:1.20.1580.10 573 699 1.2E-47 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:1.20.1580.10 270 354 2.0E-31 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:3.40.50.300 700 818 4.4E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:3.40.50.300 10 57 1.1E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:3.40.50.300 479 554 4.4E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:3.40.50.300 355 471 1.1E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 129 804 1.8E-225 T 16-09-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SUPERFAMILY SSF52540 563 792 1.02E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 SUPERFAMILY SSF52540 488 535 1.02E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 PANTHER PTHR32282:SF4 6 537 0.0 T 16-09-2016 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 ProSitePatterns PS00211 ABC transporters family signature. 709 723 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28785 258dbef37652301cc63ab859e83ecaab 822 Gene3D G3DSA:1.10.8.280 160 269 3.0E-24 T 16-09-2016 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 Gene3D G3DSA:2.130.10.80 259 550 6.4E-67 T 16-09-2016 IPR015916 Galactose oxidase, beta-propeller Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 Gene3D G3DSA:2.130.10.80 54 137 6.4E-67 T 16-09-2016 IPR015916 Galactose oxidase, beta-propeller Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 Gene3D G3DSA:2.60.40.10 551 644 1.6E-26 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 SUPERFAMILY SSF81296 546 644 4.62E-22 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 SUPERFAMILY SSF50965 50 143 5.89E-6 T 16-09-2016 IPR011043 Galactose oxidase/kelch, beta-propeller Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 PANTHER PTHR32208:SF21 259 645 5.6E-124 T 16-09-2016 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 PANTHER PTHR32208:SF21 6 139 5.6E-124 T 16-09-2016 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 SUPERFAMILY SSF50965 264 546 1.11E-34 T 16-09-2016 IPR011043 Galactose oxidase/kelch, beta-propeller Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 Pfam PF09118 Domain of unknown function (DUF1929) 550 644 4.1E-22 T 16-09-2016 IPR015202 Domain of unknown function DUF1929 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 PANTHER PTHR32208 259 645 5.6E-124 T 16-09-2016 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 PANTHER PTHR32208 6 139 5.6E-124 T 16-09-2016 Spa2297_RS12130 b449479e066092e94a9b3e9d6587baa1 645 Pfam PF07646 Kelch motif 287 330 8.3E-6 T 16-09-2016 IPR011498 Kelch repeat type 2 GO:0005515 Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 PANTHER PTHR11751:SF301 1 375 3.3E-96 T 16-09-2016 Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 Gene3D G3DSA:3.90.1150.10 250 376 1.6E-22 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 SUPERFAMILY SSF53383 18 377 7.18E-96 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 Gene3D G3DSA:3.40.640.10 38 249 3.6E-70 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 PANTHER PTHR11751 1 375 3.3E-96 T 16-09-2016 Spa2297_RS02875 450e978b4ad6b59bd41e7d1a612c022f 379 Pfam PF00155 Aminotransferase class I and II 28 372 2.0E-59 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 PANTHER PTHR24220 10 325 1.0E-118 T 16-09-2016 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 287 7.9E-13 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 Gene3D G3DSA:3.40.50.300 7 253 1.8E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 Pfam PF00005 ABC transporter 31 181 2.6E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 PANTHER PTHR24220:SF336 10 325 1.0E-118 T 16-09-2016 Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 SMART SM00382 39 238 4.2E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 SUPERFAMILY SSF52540 8 252 8.28E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24190 a2cf0457048a51b0dbc8061d0897709e 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 1.8E-19 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 Gene3D G3DSA:1.20.1560.10 23 343 5.8E-64 T 16-09-2016 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 PANTHER PTHR24221 3 600 6.1E-231 T 16-09-2016 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 SUPERFAMILY SSF90123 19 345 2.09E-65 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 SUPERFAMILY SSF52540 346 591 5.22E-91 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 Pfam PF00005 ABC transporter 374 523 2.4E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 Gene3D G3DSA:3.40.50.300 357 587 5.8E-82 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 PANTHER PTHR24221:SF161 3 600 6.1E-231 T 16-09-2016 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 Pfam PF00664 ABC transporter transmembrane region 40 310 2.1E-34 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS04080 df071356d525e37063727e785eebb47e 600 SMART SM00382 383 569 3.1E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 2.8E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 2.8E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 2.8E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 Gene3D G3DSA:3.30.565.10 200 368 2.1E-36 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 1.1E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 SMART SM00388 150 214 1.2E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 SUPERFAMILY SSF47384 137 214 7.65E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 SMART SM00387 259 369 4.9E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 Gene3D G3DSA:1.10.287.130 142 199 2.2E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 PANTHER PTHR24423 129 370 3.7E-69 T 16-09-2016 Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 SUPERFAMILY SSF55874 204 367 1.24E-36 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17150 504ce8dd5f6073835141221f471572da 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 368 1.8E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 319 2.7E-113 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 Gene3D G3DSA:3.40.50.300 4 233 2.4E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 SMART SM00382 34 217 1.2E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 PANTHER PTHR24220:SF0 11 232 5.2E-100 T 16-09-2016 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 Pfam PF00005 ABC transporter 26 168 3.6E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 PANTHER PTHR24220:SF0 307 317 5.2E-100 T 16-09-2016 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 PANTHER PTHR24220 307 317 5.2E-100 T 16-09-2016 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 PANTHER PTHR24220 11 232 5.2E-100 T 16-09-2016 Spa2297_RS16845 982a6245c8e71ad32bd70b2f984c85ea 340 SUPERFAMILY SSF52540 4 233 2.61E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 Pfam PF01595 Domain of unknown function DUF21 9 199 4.3E-40 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 SUPERFAMILY SSF54631 208 332 1.42E-15 T 16-09-2016 Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 PANTHER PTHR22777:SF18 1 330 1.1E-104 T 16-09-2016 Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 Pfam PF00571 CBS domain 284 331 5.8E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 Gene3D G3DSA:3.10.580.10 227 331 2.0E-8 T 16-09-2016 Spa2297_RS17295 836834247dd2d187df2208201278c80c 339 PANTHER PTHR22777 1 330 1.1E-104 T 16-09-2016 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 PANTHER PTHR33164 3 162 3.8E-23 T 16-09-2016 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 9.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 9.0E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 SMART SM00347 45 148 3.8E-14 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 Pfam PF01047 MarR family 54 113 7.9E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 SUPERFAMILY SSF46785 16 161 2.89E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 PANTHER PTHR33164:SF4 3 162 3.8E-23 T 16-09-2016 Spa2297_RS00065 08de758ca12b711b30e2488def2ce40f 166 Gene3D G3DSA:1.10.10.10 15 162 1.9E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Pfam PF02811 PHP domain 8 194 3.2E-43 T 16-09-2016 IPR004013 PHP domain GO:0003824 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Gene3D G3DSA:2.40.50.140 1015 1096 3.7E-4 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 SMART SM00481 7 74 7.5E-29 T 16-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 755 5.5E-162 T 16-09-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 PANTHER PTHR32294:SF0 2 1178 0.0 T 16-09-2016 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 PANTHER PTHR32294 2 1178 0.0 T 16-09-2016 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 SUPERFAMILY SSF89550 7 268 1.57E-28 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Pfam PF01336 OB-fold nucleic acid binding domain 1020 1098 2.0E-6 T 16-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Pfam PF14579 Helix-hairpin-helix motif 829 917 3.8E-23 T 16-09-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1057 0.0 T 16-09-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS08425 5536ea3cf46077d74750cbc8dae3386e 1179 Gene3D G3DSA:3.20.20.140 7 268 1.1E-37 T 16-09-2016 Spa2297_RS09790 b22c8acdc784f635ea2d36177be2a8a0 190 SUPERFAMILY SSF47090 114 183 2.07E-13 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS09790 b22c8acdc784f635ea2d36177be2a8a0 190 Gene3D G3DSA:1.10.101.10 113 186 3.3E-15 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS09790 b22c8acdc784f635ea2d36177be2a8a0 190 Pfam PF01471 Putative peptidoglycan binding domain 125 183 4.5E-13 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 Gene3D G3DSA:3.20.20.140 110 381 3.8E-49 T 16-09-2016 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 Pfam PF01979 Amidohydrolase family 104 417 4.6E-23 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 PANTHER PTHR11271 59 413 6.8E-36 T 16-09-2016 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 SUPERFAMILY SSF51338 386 417 1.79E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 SUPERFAMILY SSF51338 50 108 1.79E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 Gene3D G3DSA:2.30.40.10 386 421 7.8E-18 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 Gene3D G3DSA:2.30.40.10 50 109 7.8E-18 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 PANTHER PTHR11271:SF33 59 413 6.8E-36 T 16-09-2016 Spa2297_RS31535 1290fce82bd26288c97e33c5b3ff57aa 423 SUPERFAMILY SSF51556 108 384 2.21E-54 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS01075 8ae997fc8117232546271ef8b74baefa 148 Gene3D G3DSA:3.10.450.50 13 144 7.0E-29 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS01075 8ae997fc8117232546271ef8b74baefa 148 SUPERFAMILY SSF54427 17 144 2.18E-26 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS01075 8ae997fc8117232546271ef8b74baefa 148 Pfam PF12680 SnoaL-like domain 21 131 1.2E-12 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 Pfam PF13411 MerR HTH family regulatory protein 12 78 5.7E-14 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 Gene3D G3DSA:1.10.1660.10 14 87 1.3E-13 T 16-09-2016 Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 SMART SM00422 8 80 1.5E-16 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 SUPERFAMILY SSF46955 12 96 1.17E-14 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 PANTHER PTHR30204 1 96 5.3E-57 T 16-09-2016 Spa2297_RS05060 81a1f35d4c078628321e46a7b16e3fe1 166 PANTHER PTHR30204:SF3 1 96 5.3E-57 T 16-09-2016 Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 SUPERFAMILY SSF52540 10 229 4.31E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 PANTHER PTHR24220 11 223 8.4E-81 T 16-09-2016 Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 PANTHER PTHR24220:SF111 11 223 8.4E-81 T 16-09-2016 Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 SMART SM00382 35 223 7.3E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 Pfam PF00005 ABC transporter 26 175 1.7E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23880 61c43314af2f45e940417adb3077feb4 258 Gene3D G3DSA:3.40.50.300 9 226 2.2E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Gene3D G3DSA:1.10.540.10 35 147 8.7E-4 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Gene3D G3DSA:1.20.140.10 273 466 4.9E-41 T 16-09-2016 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 PANTHER PTHR10909 7 482 4.5E-246 T 16-09-2016 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 7.7E-11 T 16-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 SUPERFAMILY SSF56645 35 282 4.89E-41 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 2.2E-18 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 2.8E-15 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 604 2.1E-26 T 16-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 Gene3D G3DSA:2.40.110.10 161 272 1.8E-25 T 16-09-2016 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 PANTHER PTHR10909:SF340 7 482 4.5E-246 T 16-09-2016 Spa2297_RS16940 093be7d48163408c3089c430aff1a7da 608 SUPERFAMILY SSF47203 290 469 1.1E-31 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 Gene3D G3DSA:3.40.50.720 11 194 4.8E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 PANTHER PTHR10366:SF253 11 317 4.8E-119 T 16-09-2016 Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 314 2.2E-67 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 SUPERFAMILY SSF51735 7 324 3.29E-93 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 PANTHER PTHR10366 11 317 4.8E-119 T 16-09-2016 Spa2297_RS28435 e4b1df236be129f829bf0185308b8ae1 332 Gene3D G3DSA:3.90.25.10 195 323 4.0E-29 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PANTHER PTHR23501 21 531 1.5E-248 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 Gene3D G3DSA:1.20.1250.20 276 434 1.4E-17 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 Gene3D G3DSA:1.20.1250.20 486 510 1.4E-17 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 4.5E-9 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 4.5E-9 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 4.5E-9 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 88 110 4.5E-9 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 Gene3D G3DSA:1.20.1250.20 22 205 7.8E-29 T 16-09-2016 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 SUPERFAMILY SSF103473 261 432 1.44E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 SUPERFAMILY SSF103473 485 511 1.44E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 SUPERFAMILY SSF103473 19 209 1.44E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 Pfam PF07690 Major Facilitator Superfamily 30 421 3.8E-45 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS06890 ea3e0a7a4f244083190437b228bc437a 535 PANTHER PTHR23501:SF65 21 531 1.5E-248 T 16-09-2016 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 Pfam PF02342 TerD domain 1 170 9.3E-35 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 PANTHER PTHR32097 1 339 4.3E-188 T 16-09-2016 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 PANTHER PTHR32097 415 555 4.3E-188 T 16-09-2016 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 SUPERFAMILY SSF51219 366 565 1.99E-30 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 Gene3D G3DSA:2.60.60.30 29 168 1.5E-26 T 16-09-2016 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 Gene3D G3DSA:3.60.160.10 368 552 4.9E-26 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 Pfam PF01987 Mitochondrial biogenesis AIM24 370 556 1.4E-20 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 PANTHER PTHR32097:SF3 1 339 4.3E-188 T 16-09-2016 Spa2297_RS21940 6fa7bca20b91d462ab032f0763e1bc3d 566 PANTHER PTHR32097:SF3 415 555 4.3E-188 T 16-09-2016 Spa2297_RS21270 33aa5d3abc4d40ca34ef1745d428b4b9 265 Gene3D G3DSA:3.40.50.150 43 264 2.4E-20 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21270 33aa5d3abc4d40ca34ef1745d428b4b9 265 Pfam PF08241 Methyltransferase domain 57 150 1.2E-6 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS21270 33aa5d3abc4d40ca34ef1745d428b4b9 265 SUPERFAMILY SSF53335 39 218 2.32E-19 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21270 33aa5d3abc4d40ca34ef1745d428b4b9 265 PANTHER PTHR10108:SF746 22 248 1.5E-75 T 16-09-2016 Spa2297_RS21270 33aa5d3abc4d40ca34ef1745d428b4b9 265 PANTHER PTHR10108 22 248 1.5E-75 T 16-09-2016 Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 SUPERFAMILY SSF63829 10 278 1.9E-63 T 16-09-2016 Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PANTHER PTHR10907:SF47 9 284 4.7E-74 T 16-09-2016 Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 Gene3D G3DSA:2.120.10.30 10 281 4.7E-81 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PANTHER PTHR10907 9 284 4.7E-74 T 16-09-2016 Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 19 36 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 92 113 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 195 212 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 133 155 4.9E-41 T 16-09-2016 IPR005511 Senescence marker protein-30 (SMP-30) Spa2297_RS10285 64b96bc4c96eb12bee4abf802f942b91 286 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 18 256 1.9E-78 T 16-09-2016 IPR013658 SMP-30/Gluconolactonase/LRE-like region Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 Pfam PF13560 Helix-turn-helix domain 8 86 4.5E-17 T 16-09-2016 Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 Gene3D G3DSA:1.10.260.40 3 81 5.1E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 SUPERFAMILY SSF47413 22 81 1.6E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 PANTHER PTHR35010:SF2 8 279 2.3E-71 T 16-09-2016 Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 PANTHER PTHR35010 8 279 2.3E-71 T 16-09-2016 Spa2297_RS12255 882fae2d6b1e84d7c83baf5c64672e34 279 SMART SM00530 11 83 3.5E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 Gene3D G3DSA:3.40.309.10 268 450 6.4E-61 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 Gene3D G3DSA:3.40.605.10 10 267 1.9E-78 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 SUPERFAMILY SSF53720 6 479 6.68E-149 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 Pfam PF00171 Aldehyde dehydrogenase family 26 475 1.0E-149 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 PANTHER PTHR11699:SF203 1 486 1.1E-302 T 16-09-2016 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS18110 6590731aff34a8940d4763f2939cd5ba 486 PANTHER PTHR11699 1 486 1.1E-302 T 16-09-2016 Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 SUPERFAMILY SSF51735 11 249 2.16E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PANTHER PTHR24322 157 188 9.7E-79 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PANTHER PTHR24322 13 141 9.7E-79 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 Gene3D G3DSA:3.40.50.720 12 246 2.7E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 Pfam PF00106 short chain dehydrogenase 11 199 2.0E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.5E-14 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.5E-14 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.5E-14 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.5E-14 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.5E-14 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PANTHER PTHR24322:SF333 157 188 9.7E-79 T 16-09-2016 Spa2297_RS20435 4125570a9b06e5904776b71a5443911f 251 PANTHER PTHR24322:SF333 13 141 9.7E-79 T 16-09-2016 Spa2297_RS21760 46968f88766a12e189b9eb5199f6f254 198 Pfam PF05076 Suppressor of fused protein (SUFU) 29 193 1.6E-34 T 16-09-2016 IPR020941 Suppressor of fused-like domain Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 PANTHER PTHR11751:SF303 8 397 2.2E-190 T 16-09-2016 Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 SUPERFAMILY SSF53383 5 398 1.09E-96 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 PANTHER PTHR11751 8 397 2.2E-190 T 16-09-2016 Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 Pfam PF00155 Aminotransferase class I and II 34 390 3.3E-51 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 Gene3D G3DSA:3.90.1150.10 278 401 2.5E-41 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS26365 6eaa52350ff9159e5f81b16c5386fc8c 402 Gene3D G3DSA:3.40.640.10 50 277 3.5E-68 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 SUPERFAMILY SSF51197 36 324 6.41E-69 T 16-09-2016 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 PANTHER PTHR10696 31 325 1.4E-42 T 16-09-2016 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 Gene3D G3DSA:3.60.130.10 36 170 3.0E-62 T 16-09-2016 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 Gene3D G3DSA:3.60.130.10 202 326 3.0E-62 T 16-09-2016 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 PANTHER PTHR10696:SF27 31 325 1.4E-42 T 16-09-2016 Spa2297_RS00680 a61ba73b5140be2c6d13dfa099dc2608 339 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 35 321 1.7E-43 T 16-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 SUPERFAMILY SSF48179 206 293 2.21E-13 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 Gene3D G3DSA:3.40.50.720 20 207 8.2E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 SUPERFAMILY SSF51735 25 203 2.15E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 Hamap MF_02129 L-carnitine dehydrogenase [lcdH]. 26 336 51.532 T 16-09-2016 IPR026578 L-carnitine dehydrogenase KEGG: 00040+1.1.1.10|MetaCyc: PWY-3602|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7472|UniPathway: UPA00117 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 206 292 1.6E-13 T 16-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 PANTHER PTHR23309:SF17 22 289 4.1E-104 T 16-09-2016 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 PANTHER PTHR23309 22 289 4.1E-104 T 16-09-2016 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 28 202 9.3E-43 T 16-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 Spa2297_RS03255 e3673d583e141b809503270da071cdd5 336 Gene3D G3DSA:1.10.1040.10 208 282 3.6E-8 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 Pfam PF03600 Citrate transporter 13 428 2.4E-53 T 16-09-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 PANTHER PTHR10283:SF87 271 480 1.3E-193 T 16-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 PANTHER PTHR10283:SF87 1 225 1.3E-193 T 16-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 PANTHER PTHR10283 271 480 1.3E-193 T 16-09-2016 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 PANTHER PTHR10283 1 225 1.3E-193 T 16-09-2016 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 TIGRFAM TIGR00784 citMHS: citrate transporter 1 221 4.9E-83 T 16-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 Spa2297_RS06715 534ff90e3db6381d906c51e09cfca680 480 TIGRFAM TIGR00784 citMHS: citrate transporter 277 480 9.2E-80 T 16-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 Pfam PF00294 pfkB family carbohydrate kinase 11 307 9.2E-55 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 SUPERFAMILY SSF53613 7 315 1.08E-76 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 PANTHER PTHR10584 6 317 3.1E-181 T 16-09-2016 Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 PANTHER PTHR10584:SF194 6 317 3.1E-181 T 16-09-2016 Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 8 314 1.6E-114 T 16-09-2016 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92|UniPathway: UPA00076 Spa2297_RS28475 ca19f31add2614f3a521b746bddae81c 320 Gene3D G3DSA:3.40.1190.20 7 317 2.9E-105 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 SUPERFAMILY SSF46955 1 114 5.86E-29 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 Gene3D G3DSA:1.10.1660.10 1 55 2.2E-26 T 16-09-2016 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 PANTHER PTHR30204 1 123 6.2E-27 T 16-09-2016 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 Pfam PF13411 MerR HTH family regulatory protein 1 69 4.0E-19 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 Gene3D G3DSA:1.10.1660.10 56 114 3.1E-11 T 16-09-2016 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 SMART SM00422 1 70 7.1E-33 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.9E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.9E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18740 d7cbcb0f35b6ba683f0b2aea7817127f 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.9E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Gene3D G3DSA:3.30.300.30 455 553 6.4E-34 T 16-09-2016 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Gene3D G3DSA:2.30.38.10 379 451 3.2E-24 T 16-09-2016 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Gene3D G3DSA:3.40.50.980 214 370 2.0E-39 T 16-09-2016 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Pfam PF00501 AMP-binding enzyme 34 459 2.9E-98 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 SUPERFAMILY SSF56801 27 556 6.15E-152 T 16-09-2016 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Gene3D G3DSA:3.40.50.980 28 213 2.7E-38 T 16-09-2016 Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 544 5.1E-22 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS06615 c5467ed17b1e4e1b7fdf41680540291e 559 PANTHER PTHR24096 24 551 1.7E-160 T 16-09-2016 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00385 P450 superfamily signature 346 355 9.5E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00385 P450 superfamily signature 242 259 9.5E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00385 P450 superfamily signature 277 288 9.5E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00385 P450 superfamily signature 355 366 9.5E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PANTHER PTHR24286 25 406 2.3E-78 T 16-09-2016 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 Gene3D G3DSA:1.10.630.10 15 406 2.1E-112 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 Pfam PF00067 Cytochrome P450 208 263 5.4E-7 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 Pfam PF00067 Cytochrome P450 277 376 1.2E-14 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PANTHER PTHR24286:SF42 25 406 2.3E-78 T 16-09-2016 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 196 218 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 142 158 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 95 106 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 346 355 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 295 322 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 355 366 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 PRINTS PR00359 B-class P450 signature 277 288 5.3E-33 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01655 8f9e9bacf6eba83a3bf4ac066b1e1948 407 SUPERFAMILY SSF48264 14 406 9.43E-91 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 16 285 65.122 T 16-09-2016 IPR026587 Sirtuin, class II Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 PANTHER PTHR11085:SF22 178 294 1.6E-117 T 16-09-2016 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Gene3D G3DSA:3.40.50.1220 99 136 1.9E-38 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Gene3D G3DSA:3.40.50.1220 217 291 1.9E-38 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Gene3D G3DSA:3.40.50.1220 26 49 1.9E-38 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 PANTHER PTHR11085 34 160 1.6E-117 T 16-09-2016 IPR003000 Sirtuin family GO:0070403 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 PANTHER PTHR11085 178 294 1.6E-117 T 16-09-2016 IPR003000 Sirtuin family GO:0070403 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Gene3D G3DSA:3.30.1600.10 137 210 1.4E-19 T 16-09-2016 IPR026591 Sirtuin family, catalytic core small domain Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Gene3D G3DSA:3.30.1600.10 50 84 1.4E-19 T 16-09-2016 IPR026591 Sirtuin family, catalytic core small domain Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 PANTHER PTHR11085:SF22 34 160 1.6E-117 T 16-09-2016 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 Pfam PF02146 Sir2 family 39 240 8.3E-42 T 16-09-2016 IPR003000 Sirtuin family GO:0070403 Spa2297_RS31225 65c52f83bc7f3c296af8e1685fbc67a6 299 SUPERFAMILY SSF52467 28 285 1.92E-73 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS19385 cd01a879cdcc9bfd25fa8b09a2c316a4 198 Gene3D G3DSA:3.40.50.360 4 181 8.7E-25 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS19385 cd01a879cdcc9bfd25fa8b09a2c316a4 198 PANTHER PTHR10204:SF5 3 178 1.0E-32 T 16-09-2016 Spa2297_RS19385 cd01a879cdcc9bfd25fa8b09a2c316a4 198 Pfam PF03358 NADPH-dependent FMN reductase 4 123 1.2E-13 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS19385 cd01a879cdcc9bfd25fa8b09a2c316a4 198 SUPERFAMILY SSF52218 1 186 2.73E-30 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS19385 cd01a879cdcc9bfd25fa8b09a2c316a4 198 PANTHER PTHR10204 3 178 1.0E-32 T 16-09-2016 Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 SMART SM00345 69 127 9.2E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 SMART SM00895 137 263 4.3E-13 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 SUPERFAMILY SSF48008 134 264 4.45E-18 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 SUPERFAMILY SSF46785 61 131 1.85E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 PANTHER PTHR11751 68 154 8.3E-23 T 16-09-2016 Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 68 127 2.0E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 Gene3D G3DSA:1.20.120.530 133 264 1.8E-17 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 Gene3D G3DSA:1.10.10.10 53 127 7.8E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26110 2771ee21ced9a8573f367914a23cea28 265 Pfam PF07729 FCD domain 137 261 1.5E-18 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 PANTHER PTHR22604 267 409 5.3E-103 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 172 244 5.3E-11 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 PANTHER PTHR22604:SF123 30 247 5.3E-103 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 Gene3D G3DSA:3.40.50.720 26 180 7.8E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 SUPERFAMILY SSF55347 166 338 3.6E-35 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 PANTHER PTHR22604 30 247 5.3E-103 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 Gene3D G3DSA:3.30.360.10 181 318 3.0E-51 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 Gene3D G3DSA:3.30.360.10 366 409 3.0E-51 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 PANTHER PTHR22604:SF123 267 409 5.3E-103 T 16-09-2016 Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 SUPERFAMILY SSF51735 25 192 1.47E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27360 4c24d85d3fe211ccc31332567bd63351 417 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 31 152 3.3E-25 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 PANTHER PTHR24023 71 378 1.3E-25 T 16-09-2016 Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 SUPERFAMILY SSF89796 1 390 5.1E-122 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 Gene3D G3DSA:3.40.50.10540 2 213 6.4E-98 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 Gene3D G3DSA:3.40.50.10540 304 390 6.4E-98 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 Gene3D G3DSA:3.30.1540.10 219 303 1.5E-25 T 16-09-2016 Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 PANTHER PTHR24023:SF593 71 378 1.3E-25 T 16-09-2016 Spa2297_RS13590 77d9a1025ff4f44df10ed2997ee5a44c 391 Pfam PF02515 CoA-transferase family III 4 368 1.1E-111 T 16-09-2016 IPR003673 CoA-transferase family III GO:0003824 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 Gene3D G3DSA:3.30.2110.10 21 193 2.4E-57 T 16-09-2016 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 25 329 1.0E-49 T 16-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 SUPERFAMILY SSF111342 14 295 6.28E-81 T 16-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 Pfam PF01888 CbiD 18 278 5.6E-87 T 16-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 PANTHER PTHR35863 7 372 2.2E-100 T 16-09-2016 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 18 369 27.53 T 16-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 PIRSF PIRSF026782 14 372 5.1E-123 T 16-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS00600 5075fc1929b633ef2f12d32632f6e45a 372 PANTHER PTHR35863:SF1 7 372 2.2E-100 T 16-09-2016 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 Pfam PF02601 Exonuclease VII, large subunit 129 350 1.4E-61 T 16-09-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 Pfam PF02601 Exonuclease VII, large subunit 319 397 4.5E-10 T 16-09-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 PANTHER PTHR30008:SF0 3 402 1.2E-144 T 16-09-2016 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 PANTHER PTHR30008 3 402 1.2E-144 T 16-09-2016 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 3.4E-16 T 16-09-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.643 T 16-09-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS21410 ecaffa2203913ca23a16386016ae7b75 402 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 400 1.6E-119 T 16-09-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 Gene3D G3DSA:3.30.360.10 335 382 8.9E-43 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 Gene3D G3DSA:3.30.360.10 151 288 8.9E-43 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 SUPERFAMILY SSF51735 5 161 1.08E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 SUPERFAMILY SSF55347 138 325 9.81E-36 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 Gene3D G3DSA:3.40.50.720 3 150 6.0E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 PANTHER PTHR22604:SF123 237 385 3.9E-97 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 PANTHER PTHR22604:SF123 1 218 3.9E-97 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 PANTHER PTHR22604 1 218 3.9E-97 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 PANTHER PTHR22604 237 385 3.9E-97 T 16-09-2016 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 273 1.2E-12 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS28525 716f2cca154dff636b1ea773120e8171 387 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 132 1.6E-25 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 12 162 1.4E-54 T 16-09-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 PIRSF PIRSF006181 7 165 2.8E-51 T 16-09-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 PANTHER PTHR30411 12 164 6.2E-62 T 16-09-2016 Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 SUPERFAMILY SSF55826 12 162 1.7E-42 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 Pfam PF04073 Aminoacyl-tRNA editing domain 41 152 1.6E-26 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 Gene3D G3DSA:3.90.960.10 7 164 2.1E-56 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS08400 5ce52265c0e7ef893b0973204011011c 165 PANTHER PTHR30411:SF0 12 164 6.2E-62 T 16-09-2016 Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 SMART SM00345 17 76 1.0E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 PANTHER PTHR38445:SF2 1 77 6.0E-14 T 16-09-2016 Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 4.7E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 PANTHER PTHR38445 1 77 6.0E-14 T 16-09-2016 Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 Gene3D G3DSA:1.10.10.10 4 77 7.7E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06800 792a7234fa271072d958417cc1d6efcb 122 SUPERFAMILY SSF46785 7 94 1.49E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 SUPERFAMILY SSF55718 132 210 5.65E-9 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 SUPERFAMILY SSF46785 7 110 5.12E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 PANTHER PTHR33204:SF9 1 158 2.4E-69 T 16-09-2016 Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 Pfam PF01638 HxlR-like helix-turn-helix 20 104 1.3E-21 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 PANTHER PTHR33204 1 158 2.4E-69 T 16-09-2016 Spa2297_RS26370 f2426dd29c780ffdbddff9250c0c088b 213 Gene3D G3DSA:1.10.10.10 4 107 5.0E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 322 342 1.5E-17 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 358 374 1.5E-17 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 379 390 1.5E-17 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 446 462 1.5E-17 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 217 367 3.2E-49 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 77 123 7.9E-16 T 16-09-2016 IPR011096 FTP domain Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 Gene3D G3DSA:1.10.390.10 372 544 3.2E-53 T 16-09-2016 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PANTHER PTHR33794 5 544 1.7E-231 T 16-09-2016 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 SUPERFAMILY SSF55486 216 544 1.17E-82 T 16-09-2016 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 Gene3D G3DSA:3.10.170.10 217 371 2.9E-46 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 370 544 1.1E-54 T 16-09-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 Spa2297_RS23030 63ccd03a33769c76dff3756501bc25bb 545 PANTHER PTHR33794:SF2 5 544 1.7E-231 T 16-09-2016 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 Pfam PF00005 ABC transporter 17 160 1.7E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 Gene3D G3DSA:3.40.50.300 2 223 3.7E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 PANTHER PTHR24220 273 294 5.0E-141 T 16-09-2016 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 PANTHER PTHR24220 3 224 5.0E-141 T 16-09-2016 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 SMART SM00382 25 208 3.8E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 PANTHER PTHR24220:SF563 273 294 5.0E-141 T 16-09-2016 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 PANTHER PTHR24220:SF563 3 224 5.0E-141 T 16-09-2016 Spa2297_RS16245 c38d042270f0fccc8b0a53e892d83ec9 320 SUPERFAMILY SSF52540 7 210 1.91E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 316 1.3E-85 T 16-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 313 29.154 T 16-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 PIRSF PIRSF005303 3 316 4.8E-91 T 16-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 SUPERFAMILY SSF55326 5 142 8.97E-35 T 16-09-2016 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 Gene3D G3DSA:3.90.650.10 151 316 4.8E-51 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 246 2.5E-5 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 Gene3D G3DSA:3.30.1330.10 4 146 3.0E-46 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 3.8E-22 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 PANTHER PTHR30270:SF0 1 322 4.9E-118 T 16-09-2016 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 PANTHER PTHR30270 1 322 4.9E-118 T 16-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 Spa2297_RS23595 44753e4cd445acb2688e25d8995f6475 322 SUPERFAMILY SSF56042 148 296 2.09E-32 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 PANTHER PTHR35908 50 142 7.3E-42 T 16-09-2016 Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 PANTHER PTHR35908 2 34 7.3E-42 T 16-09-2016 Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 PANTHER PTHR35908:SF1 50 142 7.3E-42 T 16-09-2016 Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 PANTHER PTHR35908:SF1 2 34 7.3E-42 T 16-09-2016 Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 Gene3D G3DSA:3.10.180.10 8 142 1.2E-9 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS25915 56f9937d5d00fdbe31c57d3ab2341421 143 SUPERFAMILY SSF54593 5 142 3.18E-9 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02140 fe9cd16854682af3159daf5bf533f587 204 PANTHER PTHR30086:SF0 4 201 5.2E-82 T 16-09-2016 Spa2297_RS02140 fe9cd16854682af3159daf5bf533f587 204 Pfam PF01810 LysE type translocator 16 201 1.3E-40 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS02140 fe9cd16854682af3159daf5bf533f587 204 PANTHER PTHR30086 4 201 5.2E-82 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PANTHER PTHR33164:SF2 41 158 2.3E-26 T 16-09-2016 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PANTHER PTHR33164 41 158 2.3E-26 T 16-09-2016 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 Pfam PF01047 MarR family 44 99 1.1E-13 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 Gene3D G3DSA:1.10.10.10 35 148 2.7E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 SUPERFAMILY SSF46785 39 148 8.63E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.7E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.7E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.7E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.7E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20975 5f22768fc87c3cb8fe8173bb072544d3 166 SMART SM00347 43 134 1.3E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 359 547 2.9E-44 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 PANTHER PTHR21021:SF19 260 556 3.8E-42 T 16-09-2016 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 PANTHER PTHR21021 260 556 3.8E-42 T 16-09-2016 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SMART SM00331 333 547 1.1E-21 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Pfam PF01590 GAF domain 153 305 2.4E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Gene3D G3DSA:3.30.450.40 140 312 1.3E-25 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 129 1.9E-9 T 16-09-2016 IPR000014 PAS domain Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SUPERFAMILY SSF55874 586 677 4.28E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Pfam PF08448 PAS fold 16 128 7.9E-17 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Gene3D G3DSA:3.30.565.10 588 677 1.6E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Gene3D G3DSA:3.30.450.20 12 127 1.2E-18 T 16-09-2016 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SUPERFAMILY SSF55785 11 125 5.76E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SUPERFAMILY SSF55781 216 309 5.45E-13 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SMART SM00091 10 76 7.2E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 SMART SM00065 149 315 2.2E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS18730 6b38b1e5218a6ee89a8c702e34ba70a1 699 Pfam PF13581 Histidine kinase-like ATPase domain 561 667 6.1E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 Gene3D G3DSA:1.10.10.60 25 69 2.3E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 9.4E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 9.4E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 SUPERFAMILY SSF46689 19 97 9.45E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 PANTHER PTHR30055:SF10 14 220 1.6E-69 T 16-09-2016 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 Gene3D G3DSA:1.10.357.10 70 215 1.1E-30 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 PANTHER PTHR30055 14 220 1.6E-69 T 16-09-2016 Spa2297_RS09990 e29b2f5e0729ae82748c00f6496151c9 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 71 4.1E-17 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 SUPERFAMILY SSF53335 4 227 2.94E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 16-09-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 1.8E-60 T 16-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 PANTHER PTHR10108 12 229 2.1E-76 T 16-09-2016 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 Gene3D G3DSA:3.40.50.150 12 228 3.2E-47 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 PANTHER PTHR10108:SF24 12 229 2.1E-76 T 16-09-2016 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 34.87 T 16-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 2.8E-73 T 16-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS19165 aedac5af302a91b2472b9a25878270d9 231 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 16-09-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 20 497 1.0E-111 T 16-09-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 SUPERFAMILY SSF103473 268 495 2.96E-30 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 SUPERFAMILY SSF103473 13 219 2.96E-30 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 89 113 - T 16-09-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 Pfam PF00854 POT family 100 467 2.4E-60 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 PANTHER PTHR11654:SF119 23 231 5.1E-107 T 16-09-2016 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 PANTHER PTHR11654:SF119 280 466 5.1E-107 T 16-09-2016 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 162 174 - T 16-09-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 Gene3D G3DSA:1.20.1250.20 42 214 5.6E-16 T 16-09-2016 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 Gene3D G3DSA:1.20.1250.20 296 491 1.1E-6 T 16-09-2016 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 PANTHER PTHR11654 23 231 5.1E-107 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00505 0c3ba3311445cc92073bd4f1a9fac185 501 PANTHER PTHR11654 280 466 5.1E-107 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 SUPERFAMILY SSF53218 146 286 3.4E-27 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Gene3D G3DSA:2.40.340.10 297 350 2.8E-4 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 SUPERFAMILY SSF63867 294 357 2.94E-5 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Pfam PF00994 Probable molybdopterin binding domain 150 284 7.8E-22 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Pfam PF03453 MoeA N-terminal region (domain I and II) 1 136 3.5E-25 T 16-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Gene3D G3DSA:2.170.190.11 22 101 2.2E-17 T 16-09-2016 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 SUPERFAMILY SSF63882 1 145 5.23E-31 T 16-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Gene3D G3DSA:3.40.980.10 132 295 3.1E-38 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Pfam PF03454 MoeA C-terminal region (domain IV) 297 359 3.4E-8 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 Gene3D G3DSA:3.90.105.10 102 131 3.6E-9 T 16-09-2016 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 PANTHER PTHR10192 1 370 1.8E-83 T 16-09-2016 Spa2297_RS16830 33404e0aacd95d21f0f2a0bb70e01998 373 SMART SM00852 149 285 2.6E-20 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 Pfam PF10728 Domain of unknown function (DUF2520) 149 275 5.2E-38 T 16-09-2016 IPR018931 Domain of unknown function DUF2520 Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 Gene3D G3DSA:3.40.50.720 16 178 1.5E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 Pfam PF10727 Rossmann-like domain 8 132 1.0E-43 T 16-09-2016 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 PANTHER PTHR40459:SF1 6 310 6.7E-114 T 16-09-2016 Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 PANTHER PTHR40459 6 310 6.7E-114 T 16-09-2016 Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 SUPERFAMILY SSF51735 18 180 5.17E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 Gene3D G3DSA:1.10.1040.20 182 279 5.3E-32 T 16-09-2016 IPR018931 Domain of unknown function DUF2520 Spa2297_RS18280 b97be7c549920ace49bf61872573ae00 351 SUPERFAMILY SSF48179 182 281 2.01E-24 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS13155 b49b694ca54b9d13d6f011dc6f81f88f 326 SUPERFAMILY SSF48150 127 306 1.53E-26 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS13155 b49b694ca54b9d13d6f011dc6f81f88f 326 Gene3D G3DSA:1.10.340.30 141 249 1.5E-16 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 313 3.2E-23 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 SUPERFAMILY SSF52540 6 257 3.38E-75 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 PANTHER PTHR24220 7 337 2.7E-166 T 16-09-2016 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 Gene3D G3DSA:3.40.50.300 4 259 2.8E-83 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 SMART SM00382 42 235 1.5E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 PANTHER PTHR24220:SF336 7 337 2.7E-166 T 16-09-2016 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 1.3E-17 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21605 8440d3ba70c223d7287a409f74194797 354 Pfam PF00005 ABC transporter 34 185 6.7E-34 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS13100 0c9553090023300c4a0c730f501c84e4 375 Gene3D G3DSA:3.40.50.10490 225 374 4.6E-9 T 16-09-2016 Spa2297_RS13100 0c9553090023300c4a0c730f501c84e4 375 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 226 374 6.8E-22 T 16-09-2016 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 Spa2297_RS13100 0c9553090023300c4a0c730f501c84e4 375 SUPERFAMILY SSF53697 98 374 2.61E-44 T 16-09-2016 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 879 2.6E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 891 2.6E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 849 863 2.6E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 SMART SM00421 846 903 5.0E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 SUPERFAMILY SSF46894 840 905 3.74E-15 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 SUPERFAMILY SSF48452 518 664 7.11E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Gene3D G3DSA:1.25.40.10 710 820 4.9E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Gene3D G3DSA:1.25.40.10 509 669 4.9E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Gene3D G3DSA:1.25.40.10 380 416 4.9E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Gene3D G3DSA:1.10.10.10 845 905 3.7E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Pfam PF00196 Bacterial regulatory proteins, luxR family 848 902 4.4E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 SUPERFAMILY SSF52540 17 194 9.55E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30145 0477cdf3825658ead77e952f68cf9e8f 919 Gene3D G3DSA:3.40.50.300 18 126 4.5E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS32035 76d464cc1bb3aa8be0467c1dd1bcea99 268 SUPERFAMILY SSF52096 12 267 5.76E-81 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS32035 76d464cc1bb3aa8be0467c1dd1bcea99 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 267 3.2E-56 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS32035 76d464cc1bb3aa8be0467c1dd1bcea99 268 Gene3D G3DSA:3.90.226.10 15 266 4.7E-78 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS32035 76d464cc1bb3aa8be0467c1dd1bcea99 268 PANTHER PTHR11941:SF93 2 265 5.5E-133 T 16-09-2016 Spa2297_RS32035 76d464cc1bb3aa8be0467c1dd1bcea99 268 PANTHER PTHR11941 2 265 5.5E-133 T 16-09-2016 Spa2297_RS20495 f265a27ce0c2eaa14a000e2017f2ccfd 136 SUPERFAMILY SSF54593 9 126 1.15E-20 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS20495 f265a27ce0c2eaa14a000e2017f2ccfd 136 Gene3D G3DSA:3.10.180.10 11 129 1.9E-15 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS10515 d5039c49d21b0abeae3a89c90d68bb78 149 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 110 144 1.1E-4 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS10515 d5039c49d21b0abeae3a89c90d68bb78 149 Pfam PF05901 Excalibur calcium-binding domain 33 67 2.1E-10 T 16-09-2016 IPR008613 Excalibur calcium-binding domain Spa2297_RS10515 d5039c49d21b0abeae3a89c90d68bb78 149 SMART SM00894 32 68 2.7E-15 T 16-09-2016 IPR008613 Excalibur calcium-binding domain Spa2297_RS12430 fbf2e78981bec432df4e6e958098e771 431 PANTHER PTHR30009 18 424 1.2E-186 T 16-09-2016 Spa2297_RS12430 fbf2e78981bec432df4e6e958098e771 431 PANTHER PTHR30009:SF2 18 424 1.2E-186 T 16-09-2016 Spa2297_RS12430 fbf2e78981bec432df4e6e958098e771 431 Pfam PF02378 Phosphotransferase system, EIIC 26 353 2.5E-66 T 16-09-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 Spa2297_RS28420 9377796881fa719a5c8c90e06d5ce9c0 174 PANTHER PTHR34796:SF1 3 173 2.3E-34 T 16-09-2016 Spa2297_RS28420 9377796881fa719a5c8c90e06d5ce9c0 174 Gene3D G3DSA:1.10.3450.10 28 162 1.7E-23 T 16-09-2016 IPR023203 TTHA0068-like domain Spa2297_RS28420 9377796881fa719a5c8c90e06d5ce9c0 174 PANTHER PTHR34796 3 173 2.3E-34 T 16-09-2016 Spa2297_RS28420 9377796881fa719a5c8c90e06d5ce9c0 174 Pfam PF03745 Domain of unknown function (DUF309) 60 117 4.0E-19 T 16-09-2016 IPR005500 Protein of unknown function DUF309 Spa2297_RS28420 9377796881fa719a5c8c90e06d5ce9c0 174 SUPERFAMILY SSF140663 41 160 4.84E-26 T 16-09-2016 IPR023203 TTHA0068-like domain Spa2297_RS26035 87cfcbb023f94fb80b1a1f2ab6814e68 66 Gene3D G3DSA:3.30.70.900 6 62 3.1E-14 T 16-09-2016 Spa2297_RS26035 87cfcbb023f94fb80b1a1f2ab6814e68 66 SUPERFAMILY SSF54909 9 51 1.77E-7 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 SUPERFAMILY SSF56801 16 543 8.11E-128 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 PANTHER PTHR24095 17 540 5.1E-203 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Pfam PF00501 AMP-binding enzyme 52 446 7.5E-74 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Gene3D G3DSA:3.30.300.30 445 546 3.2E-21 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 532 4.0E-17 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Gene3D G3DSA:2.30.38.10 364 440 5.0E-18 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Gene3D G3DSA:3.40.50.980 52 204 1.7E-25 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 Gene3D G3DSA:3.40.50.980 205 363 1.4E-26 T 16-09-2016 Spa2297_RS26265 5a4f3e847a5c8f62d6678e0c03acfe86 556 PANTHER PTHR24095:SF180 17 540 5.1E-203 T 16-09-2016 Spa2297_RS27000 f6da9bbd8a541ce784a000bc3075bef8 277 Gene3D G3DSA:3.30.1360.130 216 267 1.0E-7 T 16-09-2016 Spa2297_RS27000 f6da9bbd8a541ce784a000bc3075bef8 277 Gene3D G3DSA:3.40.50.10780 1 213 2.2E-75 T 16-09-2016 IPR027476 D-aminopeptidase, N-terminal Spa2297_RS27000 f6da9bbd8a541ce784a000bc3075bef8 277 SUPERFAMILY SSF63992 1 267 1.57E-84 T 16-09-2016 IPR007035 Peptidase M55, D-aminopeptidase Spa2297_RS27000 f6da9bbd8a541ce784a000bc3075bef8 277 Pfam PF04951 D-aminopeptidase 1 262 4.9E-91 T 16-09-2016 IPR007035 Peptidase M55, D-aminopeptidase Spa2297_RS27000 f6da9bbd8a541ce784a000bc3075bef8 277 PIRSF PIRSF015853 1 274 1.8E-98 T 16-09-2016 IPR007035 Peptidase M55, D-aminopeptidase Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 TIGRFAM TIGR01076 sortase_fam: sortase 189 328 5.6E-15 T 16-09-2016 IPR005754 Sortase family Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 PANTHER PTHR33393 47 342 5.6E-133 T 16-09-2016 Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 Pfam PF04203 Sortase family 190 327 5.6E-26 T 16-09-2016 IPR005754 Sortase family Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 SUPERFAMILY SSF63817 182 328 1.83E-29 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 Gene3D G3DSA:2.40.260.10 184 330 3.6E-28 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS16710 e3762bcfdad7d7e0279bd9032907138b 342 PANTHER PTHR33393:SF3 47 342 5.6E-133 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 Gene3D G3DSA:3.50.50.60 3 114 5.5E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PANTHER PTHR22912 1 300 3.2E-127 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 Gene3D G3DSA:3.50.50.60 115 301 1.4E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PANTHER PTHR22912:SF152 1 300 3.2E-127 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.2E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.2E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 1.2E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 1.2E-13 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 SUPERFAMILY SSF51905 5 315 4.75E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.9E-13 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.9E-13 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.9E-13 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 3.9E-13 T 16-09-2016 Spa2297_RS28640 cf15fd174cab16621cf74fae756ed2d5 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 296 1.7E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00450 8eed8bb6463eb9e49d6613b548b232b7 200 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 4 176 1.2E-14 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 2.1E-6 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 198 2.1E-6 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 365 2.1E-6 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 PANTHER PTHR22924 2 396 2.2E-85 T 16-09-2016 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 Pfam PF00175 Oxidoreductase NAD-binding domain 272 371 1.8E-9 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 SUPERFAMILY SSF52343 264 391 2.62E-30 T 16-09-2016 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 SUPERFAMILY SSF63380 155 261 1.69E-26 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 Gene3D G3DSA:1.10.490.10 2 145 7.3E-40 T 16-09-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 SUPERFAMILY SSF46458 2 144 2.99E-29 T 16-09-2016 IPR009050 Globin-like Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 Pfam PF00970 Oxidoreductase FAD-binding domain 159 259 2.7E-9 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 Gene3D G3DSA:3.40.50.80 265 392 1.0E-27 T 16-09-2016 Spa2297_RS01600 d6882a9ace9c70badcdff5af87c0da76 400 Gene3D G3DSA:2.40.30.10 155 261 1.1E-31 T 16-09-2016 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 Pfam PF01434 Peptidase family M41 402 609 1.9E-80 T 16-09-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 PANTHER PTHR23076 5 622 5.7E-303 T 16-09-2016 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 9.6E-45 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 Gene3D G3DSA:1.10.8.60 348 414 1.6E-23 T 16-09-2016 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 SUPERFAMILY SSF52540 161 411 1.13E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 1.7E-232 T 16-09-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 16-09-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 SUPERFAMILY SSF140990 421 615 2.62E-73 T 16-09-2016 Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 Gene3D G3DSA:3.40.50.300 163 347 4.5E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 SMART SM00382 203 342 6.2E-25 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18180 d8f2f71b740b6183734784cd4fff1ce2 677 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.245 T 16-09-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 SUPERFAMILY SSF53697 4 289 7.12E-45 T 16-09-2016 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 Gene3D G3DSA:3.40.50.10490 3 147 1.2E-17 T 16-09-2016 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 PANTHER PTHR10937 34 292 2.8E-28 T 16-09-2016 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 Pfam PF01380 SIS domain 34 136 5.0E-6 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 Gene3D G3DSA:3.40.50.10490 252 289 8.4E-8 T 16-09-2016 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 Gene3D G3DSA:3.40.50.10490 169 247 1.4E-20 T 16-09-2016 Spa2297_RS03490 5556c6e73efa1dd5d3ee13edcf968f74 293 PANTHER PTHR10937:SF4 34 292 2.8E-28 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 Pfam PF03176 MMPL family 398 708 1.0E-27 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 Pfam PF03176 MMPL family 46 368 1.4E-49 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 PANTHER PTHR33406:SF1 9 734 3.5E-131 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 PANTHER PTHR33406 9 734 3.5E-131 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 SUPERFAMILY SSF82866 111 336 9.94E-36 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 SUPERFAMILY SSF82866 491 705 8.89E-27 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 Gene3D G3DSA:1.20.1640.10 134 338 1.8E-35 T 16-09-2016 Spa2297_RS03280 8680ea606b3c34bfa6963ca01b3054e1 742 Gene3D G3DSA:1.20.1640.10 492 706 1.1E-30 T 16-09-2016 Spa2297_RS06555 8d621dc98fae526e41bb58e0ac468c9c 465 Pfam PF02447 GntP family permease 27 464 8.4E-144 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS06555 8d621dc98fae526e41bb58e0ac468c9c 465 PANTHER PTHR30354 22 465 2.9E-213 T 16-09-2016 Spa2297_RS06555 8d621dc98fae526e41bb58e0ac468c9c 465 PIRSF PIRSF002746 20 465 3.2E-143 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS06555 8d621dc98fae526e41bb58e0ac468c9c 465 PANTHER PTHR30354:SF1 22 465 2.9E-213 T 16-09-2016 Spa2297_RS06555 8d621dc98fae526e41bb58e0ac468c9c 465 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 27 465 5.5E-138 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS08865 87a6e4e32296fc46da15c5728145726e 206 PANTHER PTHR11403 14 206 4.2E-73 T 16-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 Spa2297_RS08865 87a6e4e32296fc46da15c5728145726e 206 Gene3D G3DSA:1.20.120.80 25 205 1.1E-54 T 16-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Spa2297_RS08865 87a6e4e32296fc46da15c5728145726e 206 PANTHER PTHR11403:SF0 14 206 4.2E-73 T 16-09-2016 Spa2297_RS08865 87a6e4e32296fc46da15c5728145726e 206 Pfam PF00510 Cytochrome c oxidase subunit III 25 204 9.6E-24 T 16-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Spa2297_RS08865 87a6e4e32296fc46da15c5728145726e 206 SUPERFAMILY SSF81452 9 204 1.7E-55 T 16-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Spa2297_RS25375 c4ae94b0a14a1a167ab03ad5ef8dcd48 360 PANTHER PTHR31630:SF6 3 337 3.7E-101 T 16-09-2016 Spa2297_RS25375 c4ae94b0a14a1a167ab03ad5ef8dcd48 360 Gene3D G3DSA:2.60.120.620 28 279 6.8E-33 T 16-09-2016 Spa2297_RS25375 c4ae94b0a14a1a167ab03ad5ef8dcd48 360 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 51 266 1.6E-10 T 16-09-2016 IPR008775 Phytanoyl-CoA dioxygenase Spa2297_RS25375 c4ae94b0a14a1a167ab03ad5ef8dcd48 360 PANTHER PTHR31630 3 337 3.7E-101 T 16-09-2016 Spa2297_RS25375 c4ae94b0a14a1a167ab03ad5ef8dcd48 360 SUPERFAMILY SSF51197 40 333 4.85E-62 T 16-09-2016 Spa2297_RS03000 7e89b2ad1d412747ca3ce6c94172e138 284 PANTHER PTHR10108 10 159 6.8E-13 T 16-09-2016 Spa2297_RS03000 7e89b2ad1d412747ca3ce6c94172e138 284 Pfam PF13847 Methyltransferase domain 55 169 3.5E-14 T 16-09-2016 IPR025714 Methyltransferase domain Spa2297_RS03000 7e89b2ad1d412747ca3ce6c94172e138 284 PANTHER PTHR10108:SF730 10 159 6.8E-13 T 16-09-2016 Spa2297_RS03000 7e89b2ad1d412747ca3ce6c94172e138 284 Gene3D G3DSA:3.40.50.150 11 218 5.3E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03000 7e89b2ad1d412747ca3ce6c94172e138 284 SUPERFAMILY SSF53335 11 276 2.43E-25 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PANTHER PTHR11592 15 172 1.5E-81 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 Gene3D G3DSA:3.40.30.10 21 168 1.9E-62 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PANTHER PTHR11592:SF40 15 172 1.5E-81 T 16-09-2016 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 Pfam PF00255 Glutathione peroxidase 20 120 7.5E-39 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 SUPERFAMILY SSF52833 20 171 2.74E-55 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PRINTS PR01011 Glutathione peroxidase family signature 32 49 5.7E-19 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PRINTS PR01011 Glutathione peroxidase family signature 133 142 5.7E-19 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PRINTS PR01011 Glutathione peroxidase family signature 67 83 5.7E-19 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 PIRSF PIRSF000303 1 173 2.9E-64 T 16-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Spa2297_RS14215 303d34d60f91d87bc93c0f6107e02ea2 173 ProSitePatterns PS00460 Glutathione peroxidases active site. 34 49 - T 16-09-2016 IPR029759 Glutathione peroxidase active site Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 SUPERFAMILY SSF56645 217 321 4.71E-26 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 PANTHER PTHR10909 231 462 2.5E-129 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Gene3D G3DSA:2.40.110.10 221 301 2.3E-22 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 311 460 9.0E-44 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 PANTHER PTHR10909 4 143 2.5E-129 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 109 2.7E-10 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 SUPERFAMILY SSF47203 309 463 1.43E-44 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Gene3D G3DSA:1.10.540.10 4 110 2.7E-15 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Gene3D G3DSA:1.20.140.10 302 465 2.2E-52 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 116 128 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 226 296 3.3E-13 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 PANTHER PTHR10909:SF305 4 143 2.5E-129 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 PANTHER PTHR10909:SF305 231 462 2.5E-129 T 16-09-2016 Spa2297_RS25155 0c7af544f23f5a3d9fc9527113384528 473 SUPERFAMILY SSF56645 4 134 4.45E-22 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.9E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.9E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 Gene3D G3DSA:1.10.10.10 5 69 1.2E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 SUPERFAMILY SSF46785 7 80 4.73E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 SMART SM00345 8 67 7.6E-21 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 SUPERFAMILY SSF48008 93 226 4.97E-21 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 SMART SM00895 96 221 8.4E-14 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 2.0E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 Pfam PF07729 FCD domain 96 220 2.7E-20 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 PANTHER PTHR11751 7 74 4.8E-21 T 16-09-2016 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 PANTHER PTHR11751 94 113 4.8E-21 T 16-09-2016 Spa2297_RS01490 44257750bc75053c0fb68bf66efca055 229 Gene3D G3DSA:1.20.120.530 94 228 7.6E-23 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS23140 9c1af1e827250cb8b164aa1f1d0fb46a 222 SUPERFAMILY SSF52540 55 176 4.65E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23140 9c1af1e827250cb8b164aa1f1d0fb46a 222 Gene3D G3DSA:3.40.50.300 55 175 1.4E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15485 11c5a22849b3052fe23d7bf236f2929e 332 PANTHER PTHR11101 6 326 5.3E-101 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS15485 11c5a22849b3052fe23d7bf236f2929e 332 Pfam PF01384 Phosphate transporter family 165 320 1.7E-46 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS15485 11c5a22849b3052fe23d7bf236f2929e 332 Pfam PF01384 Phosphate transporter family 20 166 9.7E-41 T 16-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.2E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 PANTHER PTHR30055 2 195 1.0E-50 T 16-09-2016 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 SUPERFAMILY SSF46689 17 87 6.16E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 Gene3D G3DSA:1.10.357.10 16 176 5.6E-31 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.7E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.7E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 PANTHER PTHR30055:SF47 2 195 1.0E-50 T 16-09-2016 Spa2297_RS00555 591195a798eb7fd04a93530af1f6ad1a 212 SUPERFAMILY SSF48498 108 174 1.63E-10 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 PANTHER PTHR11070 475 758 2.2E-202 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Pfam PF13245 Part of AAA domain 240 296 1.8E-13 T 16-09-2016 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 PANTHER PTHR11070:SF25 129 402 2.2E-202 T 16-09-2016 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 PANTHER PTHR11070 129 402 2.2E-202 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Gene3D G3DSA:3.40.50.300 617 758 1.9E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Gene3D G3DSA:3.40.50.300 436 593 3.0E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Gene3D G3DSA:3.40.50.300 233 300 3.0E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Pfam PF00580 UvrD/REP helicase N-terminal domain 545 591 2.0E-6 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 SUPERFAMILY SSF52540 226 304 1.51E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 SUPERFAMILY SSF52540 387 444 1.51E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 SUPERFAMILY SSF52540 537 760 1.51E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 Pfam PF13538 UvrD-like helicase C-terminal domain 713 755 3.3E-8 T 16-09-2016 IPR027785 UvrD-like helicase C-terminal domain Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 PANTHER PTHR11070:SF25 475 758 2.2E-202 T 16-09-2016 Spa2297_RS12755 0e803a19f9ba23f6eec66b0033c359fe 773 SMART SM00382 246 713 0.0028 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 Gene3D G3DSA:3.30.470.10 2 102 3.0E-30 T 16-09-2016 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 PANTHER PTHR11825 3 265 3.0E-80 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 Gene3D G3DSA:3.20.10.10 124 258 3.1E-43 T 16-09-2016 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 SUPERFAMILY SSF56752 3 265 3.66E-69 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 Pfam PF01063 Amino-transferase class IV 29 242 2.8E-49 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 16-09-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS05885 8d4da26e38485a7d5932cb5710b0ba60 273 PANTHER PTHR11825:SF55 3 265 3.0E-80 T 16-09-2016 Spa2297_RS10580 16764596d8149946219114f9b6978776 139 PANTHER PTHR33202 11 139 2.5E-65 T 16-09-2016 Spa2297_RS10580 16764596d8149946219114f9b6978776 139 Gene3D G3DSA:1.10.10.10 11 78 7.9E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10580 16764596d8149946219114f9b6978776 139 SUPERFAMILY SSF46785 10 132 8.17E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10580 16764596d8149946219114f9b6978776 139 Pfam PF01475 Ferric uptake regulator family 11 126 2.4E-32 T 16-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spa2297_RS10580 16764596d8149946219114f9b6978776 139 PANTHER PTHR33202:SF5 11 139 2.5E-65 T 16-09-2016 Spa2297_RS30655 4b615d34bfa72161d13c1e181d425627 118 Pfam PF05239 PRC-barrel domain 5 74 2.0E-10 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS30655 4b615d34bfa72161d13c1e181d425627 118 SUPERFAMILY SSF50346 4 105 1.96E-23 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS30655 4b615d34bfa72161d13c1e181d425627 118 Gene3D G3DSA:3.90.50.10 7 101 1.0E-6 T 16-09-2016 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 Pfam PF02597 ThiS family 3 66 1.0E-14 T 16-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 PANTHER PTHR34472 1 66 1.6E-22 T 16-09-2016 Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.3E-22 T 16-09-2016 IPR010035 ThiS, thiamine-biosynthesis Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 Gene3D G3DSA:3.10.20.30 1 66 4.9E-26 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 SUPERFAMILY SSF54285 1 66 2.18E-16 T 16-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Spa2297_RS08650 9c359241e24b590f4021b713d09f7a96 66 PANTHER PTHR34472:SF1 1 66 1.6E-22 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Pfam PF00702 haloacid dehalogenase-like hydrolase 313 546 2.6E-32 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 29 692 0.0 T 16-09-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 3.3E-25 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 3.3E-25 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 3.3E-25 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 3.3E-25 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 3.3E-25 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF81665 219 310 8.76E-12 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF81665 53 118 8.76E-12 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 696 40.659 T 16-09-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF56784 455 575 6.87E-39 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF56784 304 328 6.87E-39 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF56784 364 420 6.87E-39 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Gene3D G3DSA:3.40.1110.10 327 460 2.2E-47 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Gene3D G3DSA:2.70.150.10 59 219 2.8E-24 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 318 324 - T 16-09-2016 IPR018303 P-type ATPase, phosphorylation site Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 SUPERFAMILY SSF81653 119 218 1.26E-21 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Gene3D G3DSA:3.40.50.1000 461 579 1.9E-37 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PANTHER PTHR24093 37 603 0.0 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PANTHER PTHR24093 641 695 0.0 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 Pfam PF00122 E1-E2 ATPase 87 307 7.7E-42 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 353 8.5E-31 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 388 615 5.4E-41 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PANTHER PTHR24093:SF49 37 603 0.0 T 16-09-2016 Spa2297_RS14155 c568e0d1e8f4cb3903310cb03b8ec5e6 699 PANTHER PTHR24093:SF49 641 695 0.0 T 16-09-2016 Spa2297_RS10640 ba3c141c820d9ed680f442ab91c4e812 231 Pfam PF05099 Tellurite resistance protein TerB 95 222 4.1E-7 T 16-09-2016 IPR007791 Co-chaperone DjlA, N-terminal Spa2297_RS10640 ba3c141c820d9ed680f442ab91c4e812 231 Gene3D G3DSA:1.10.3680.10 97 225 2.8E-4 T 16-09-2016 IPR029024 TerB-like Spa2297_RS10640 ba3c141c820d9ed680f442ab91c4e812 231 SUPERFAMILY SSF158682 93 225 8.5E-7 T 16-09-2016 IPR029024 TerB-like Spa2297_RS14590 2d8f3b0e08b54b27369a35f08e876ef2 330 Pfam PF00248 Aldo/keto reductase family 15 317 3.0E-67 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS14590 2d8f3b0e08b54b27369a35f08e876ef2 330 PANTHER PTHR11732:SF150 1 330 4.2E-126 T 16-09-2016 Spa2297_RS14590 2d8f3b0e08b54b27369a35f08e876ef2 330 PANTHER PTHR11732 1 330 4.2E-126 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS14590 2d8f3b0e08b54b27369a35f08e876ef2 330 Gene3D G3DSA:3.20.20.100 1 318 3.3E-94 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS14590 2d8f3b0e08b54b27369a35f08e876ef2 330 SUPERFAMILY SSF51430 1 320 6.68E-93 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Pfam PF01568 Molydopterin dinucleotide binding domain 582 688 5.8E-33 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Pfam PF00384 Molybdopterin oxidoreductase 60 485 4.2E-71 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 SUPERFAMILY SSF53706 4 583 1.7E-167 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 SMART SM00926 3 57 7.5E-12 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:3.40.50.740 373 524 1.5E-67 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:3.40.50.740 314 338 1.5E-67 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:3.40.50.740 60 133 1.5E-67 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:3.40.228.10 135 313 6.9E-54 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 PANTHER PTHR11615 1 692 2.8E-223 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:2.40.40.20 528 692 1.8E-55 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Gene3D G3DSA:2.20.25.90 5 56 1.1E-17 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 PANTHER PTHR11615:SF119 1 692 2.8E-223 T 16-09-2016 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 55 5.1E-14 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS10440 9c8a583a6fa0e747e5f85bd0a382ea39 695 SUPERFAMILY SSF50692 543 692 1.67E-47 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS16335 e58076f086514ac543609f1d8cea62e8 498 Pfam PF07907 YibE/F-like protein 223 461 3.4E-73 T 16-09-2016 IPR012507 YibE/F-like Spa2297_RS16335 e58076f086514ac543609f1d8cea62e8 498 PANTHER PTHR41771 70 478 3.7E-122 T 16-09-2016 Spa2297_RS16335 e58076f086514ac543609f1d8cea62e8 498 PANTHER PTHR41771:SF1 70 478 3.7E-122 T 16-09-2016 Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 28 75 3.6E-14 T 16-09-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 PANTHER PTHR34846:SF2 13 142 3.1E-13 T 16-09-2016 Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 SUPERFAMILY SSF69118 12 143 7.46E-36 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 Gene3D G3DSA:1.20.1290.10 13 144 8.1E-43 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 PANTHER PTHR34846 13 142 3.1E-13 T 16-09-2016 Spa2297_RS20395 e9441daa390bd41c7e2b275f9c4f5c4b 148 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 92 1.1E-12 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 174 198 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 124 141 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 322 345 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 248 274 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 16 40 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 213 241 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PRINTS PR01874 DNA repair protein radA signature 82 110 1.6E-85 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 Gene3D G3DSA:3.30.230.10 284 453 1.3E-31 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 SUPERFAMILY SSF52540 71 293 2.46E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PANTHER PTHR32472:SF10 6 469 1.3E-185 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 SUPERFAMILY SSF54211 293 453 2.35E-34 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 Gene3D G3DSA:3.40.50.300 66 275 1.2E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 PANTHER PTHR32472 6 469 1.3E-185 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 SMART SM00382 90 244 1.3E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 Pfam PF13541 Subunit ChlI of Mg-chelatase 370 429 2.7E-8 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 Pfam PF13481 AAA domain 77 222 1.6E-13 T 16-09-2016 Spa2297_RS18425 7f4dd117f134848a87b385f602550d12 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 9 450 5.3E-153 T 16-09-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Spa2297_RS07515 e83fa85807fc561dd074d9711a846b3d 281 Pfam PF14100 Methane oxygenase PmoA 9 275 1.1E-74 T 16-09-2016 IPR029475 Methane oxygenase PmoA Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 SUPERFAMILY SSF52518 3 186 4.08E-48 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 592 0.0 T 16-09-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Gene3D G3DSA:3.40.50.1220 185 335 4.5E-47 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Gene3D G3DSA:3.40.50.970 2 182 1.8E-59 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 SUPERFAMILY SSF52467 186 376 1.04E-46 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 9.5E-34 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Gene3D G3DSA:3.40.50.970 360 574 1.1E-60 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 PANTHER PTHR18968 1 578 0.0 T 16-09-2016 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 PANTHER PTHR18968:SF14 1 578 0.0 T 16-09-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 4.0E-50 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 552 4.2E-35 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS26280 5c1d5b3dd748acbc1d7aedb3d8e6451d 594 SUPERFAMILY SSF52518 369 562 1.59E-52 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 PANTHER PTHR11895 1 472 1.2E-204 T 16-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 Pfam PF01425 Amidase 57 454 4.4E-88 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 Gene3D G3DSA:3.90.1300.10 3 468 3.6E-108 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 PANTHER PTHR11895:SF35 1 472 1.2E-204 T 16-09-2016 Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 ProSitePatterns PS00571 Amidases signature. 144 175 - T 16-09-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS00560 510775fe95507a10d1182d66af43dec3 487 SUPERFAMILY SSF75304 5 473 1.44E-111 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 SUPERFAMILY SSF52374 2 154 7.04E-45 T 16-09-2016 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 155 2.1E-59 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PANTHER PTHR21342:SF1 2 158 5.8E-83 T 16-09-2016 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 Pfam PF01467 Cytidylyltransferase-like 6 132 2.7E-18 T 16-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.4E-50 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.4E-50 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.4E-50 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.4E-50 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 1.4E-50 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 PANTHER PTHR21342 2 158 5.8E-83 T 16-09-2016 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 59 3.0E-14 T 16-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 34.978 T 16-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 121 4.0E-5 T 16-09-2016 Spa2297_RS23625 fa7babbbfacef405a1ff44c12905c930 159 Gene3D G3DSA:3.40.50.620 2 155 9.7E-53 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS21455 7b69ca6afc8cbbff73149eb0dfa92b29 226 PIRSF PIRSF010219 2 225 7.5E-61 T 16-09-2016 IPR016566 Uncharacterised conserved protein UCP010219 Spa2297_RS21455 7b69ca6afc8cbbff73149eb0dfa92b29 226 Pfam PF11361 Protein of unknown function (DUF3159) 30 211 1.6E-61 T 16-09-2016 IPR016566 Uncharacterised conserved protein UCP010219 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 2.7E-39 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 Gene3D G3DSA:3.65.10.10 92 291 2.7E-39 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 PANTHER PTHR21090:SF4 38 509 4.6E-116 T 16-09-2016 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 SUPERFAMILY SSF47413 4 64 3.75E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 SUPERFAMILY SSF55205 74 506 7.03E-93 T 16-09-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 Pfam PF01381 Helix-turn-helix 13 61 2.9E-13 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 Gene3D G3DSA:1.10.260.40 3 66 1.4E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 PANTHER PTHR21090 38 509 4.6E-116 T 16-09-2016 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 Gene3D G3DSA:3.65.10.10 292 504 1.1E-36 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS25225 d86a8bcfdcf7842c5dc92df824d79eb3 509 SMART SM00530 12 67 1.4E-13 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS25275 00654726676768ff1077b968b87e2d08 430 PANTHER PTHR32196 25 217 5.7E-167 T 16-09-2016 Spa2297_RS25275 00654726676768ff1077b968b87e2d08 430 PANTHER PTHR32196 269 429 5.7E-167 T 16-09-2016 Spa2297_RS25275 00654726676768ff1077b968b87e2d08 430 PANTHER PTHR32196:SF32 25 217 5.7E-167 T 16-09-2016 Spa2297_RS25275 00654726676768ff1077b968b87e2d08 430 PANTHER PTHR32196:SF32 269 429 5.7E-167 T 16-09-2016 Spa2297_RS25275 00654726676768ff1077b968b87e2d08 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 94 413 1.1E-32 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 Pfam PF01047 MarR family 38 89 1.9E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 SUPERFAMILY SSF46785 31 140 7.4E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 Gene3D G3DSA:1.10.10.10 22 138 3.4E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.4E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.4E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.4E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 4.4E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 PANTHER PTHR33164 38 149 1.3E-22 T 16-09-2016 Spa2297_RS15995 a0182ca6e4f15a5573345a8defaa3498 166 SMART SM00347 25 125 3.4E-15 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 Pfam PF00171 Aldehyde dehydrogenase family 2 386 1.5E-41 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 SUPERFAMILY SSF53720 2 482 2.36E-81 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 Gene3D G3DSA:3.40.309.10 227 420 2.1E-51 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 PANTHER PTHR11699 1 485 2.0E-121 T 16-09-2016 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 Gene3D G3DSA:3.40.605.10 2 226 1.2E-37 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS07475 dadcca16fd8b8868f79cecc0633d31bb 488 PANTHER PTHR11699:SF10 1 485 2.0E-121 T 16-09-2016 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 SMART SM00347 32 130 1.3E-23 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 PANTHER PTHR33164 3 154 1.0E-56 T 16-09-2016 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 Pfam PF01047 MarR family 39 97 2.4E-17 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 PANTHER PTHR33164:SF5 3 154 1.0E-56 T 16-09-2016 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 SUPERFAMILY SSF46785 2 147 7.49E-38 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 5.9E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 5.9E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 5.9E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS12915 44df04a694fb8ee31e18f37740264cf7 156 Gene3D G3DSA:1.10.10.10 2 146 1.5E-43 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS33040 89c79a77dd58ed0b8517db334325ce72 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 191 305 1.6E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS33040 89c79a77dd58ed0b8517db334325ce72 305 PANTHER PTHR32243 86 305 2.3E-92 T 16-09-2016 Spa2297_RS33040 89c79a77dd58ed0b8517db334325ce72 305 Gene3D G3DSA:1.10.3720.10 90 305 1.2E-53 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS33040 89c79a77dd58ed0b8517db334325ce72 305 PANTHER PTHR32243:SF18 86 305 2.3E-92 T 16-09-2016 Spa2297_RS33040 89c79a77dd58ed0b8517db334325ce72 305 SUPERFAMILY SSF161098 93 305 3.55E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07760 fd5cd5ef4806d03420e626e2ace9971b 252 PANTHER PTHR30363 13 225 1.3E-48 T 16-09-2016 Spa2297_RS07760 fd5cd5ef4806d03420e626e2ace9971b 252 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 7.7E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS07760 fd5cd5ef4806d03420e626e2ace9971b 252 SUPERFAMILY SSF46785 19 206 2.21E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07760 fd5cd5ef4806d03420e626e2ace9971b 252 PANTHER PTHR30363:SF17 13 225 1.3E-48 T 16-09-2016 Spa2297_RS07760 fd5cd5ef4806d03420e626e2ace9971b 252 Gene3D G3DSA:1.10.10.10 21 117 2.1E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 SUPERFAMILY SSF53335 4 177 1.0E-37 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 PANTHER PTHR18895:SF64 1 193 3.7E-43 T 16-09-2016 Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 Pfam PF05175 Methyltransferase small domain 12 101 1.7E-15 T 16-09-2016 IPR007848 Methyltransferase small domain GO:0008168 Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 Gene3D G3DSA:3.40.50.150 2 176 2.6E-42 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 PANTHER PTHR18895 1 193 3.7E-43 T 16-09-2016 Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 6 181 1.1E-36 T 16-09-2016 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Spa2297_RS29915 cb151bca8e863a9c77ee0428878d8292 214 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 95 101 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Gene3D G3DSA:2.30.38.10 397 457 1.1E-20 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Gene3D G3DSA:3.40.50.980 17 189 3.7E-37 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 SUPERFAMILY SSF56801 17 288 1.03E-118 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 SUPERFAMILY SSF56801 337 596 1.03E-118 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Pfam PF00501 AMP-binding enzyme 23 466 2.2E-104 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 112 123 - T 16-09-2016 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 PANTHER PTHR24096 5 598 6.3E-216 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Gene3D G3DSA:3.30.300.30 464 585 1.1E-5 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Gene3D G3DSA:3.40.50.980 190 283 1.5E-28 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 Gene3D G3DSA:3.40.50.980 334 396 1.5E-28 T 16-09-2016 Spa2297_RS08765 79eadaf7e39afa50a9ee65407d2ceeee 598 PANTHER PTHR24096:SF193 5 598 6.3E-216 T 16-09-2016 Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PANTHER PTHR24322:SF639 14 190 2.3E-52 T 16-09-2016 Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.8E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.6E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 SUPERFAMILY SSF51735 12 251 2.14E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 Gene3D G3DSA:3.40.50.720 3 251 3.0E-83 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 PANTHER PTHR24322 14 190 2.3E-52 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS30030 3fd121febb494b685b1b7b4b99bf3b90 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 249 1.0E-67 T 16-09-2016 Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 PANTHER PTHR34698:SF2 1 205 7.2E-70 T 16-09-2016 Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 PANTHER PTHR34698 1 205 7.2E-70 T 16-09-2016 Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 Gene3D G3DSA:2.40.100.10 80 201 8.9E-48 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 SUPERFAMILY SSF50891 81 201 1.9E-39 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 Pfam PF02682 Allophanate hydrolase subunit 1 2 191 2.6E-61 T 16-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 SMART SM00796 1 191 7.1E-81 T 16-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D Spa2297_RS05265 37d49782bd35f4c0d882117f768fb23c 208 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 76 200 8.1E-45 T 16-09-2016 IPR010016 KipI family Spa2297_RS24960 bce5a9bd516acfa99d88206c471f00f3 235 PANTHER PTHR23091:SF276 76 226 2.5E-30 T 16-09-2016 Spa2297_RS24960 bce5a9bd516acfa99d88206c471f00f3 235 Pfam PF08445 FR47-like protein 143 226 1.9E-24 T 16-09-2016 IPR013653 FR47-like GO:0016747 Spa2297_RS24960 bce5a9bd516acfa99d88206c471f00f3 235 SUPERFAMILY SSF55729 83 226 1.58E-21 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24960 bce5a9bd516acfa99d88206c471f00f3 235 PANTHER PTHR23091 76 226 2.5E-30 T 16-09-2016 Spa2297_RS24960 bce5a9bd516acfa99d88206c471f00f3 235 Gene3D G3DSA:3.40.630.30 139 230 3.0E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 PANTHER PTHR11615 281 764 1.1E-277 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 PANTHER PTHR11615 1 263 1.1E-277 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 PANTHER PTHR11615:SF114 281 764 1.1E-277 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 PANTHER PTHR11615:SF114 1 263 1.1E-277 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Pfam PF00384 Molybdopterin oxidoreductase 120 418 1.8E-25 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 PIRSF PIRSF000144 1 766 0.0 T 16-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Gene3D G3DSA:3.40.228.10 194 400 5.5E-55 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 SUPERFAMILY SSF53706 58 636 6.41E-137 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Gene3D G3DSA:2.40.40.20 644 764 1.7E-11 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Pfam PF01568 Molydopterin dinucleotide binding domain 648 755 3.4E-9 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 SUPERFAMILY SSF50692 644 764 9.49E-17 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 22 761 2.6E-270 T 16-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Gene3D G3DSA:3.40.50.740 401 634 9.2E-51 T 16-09-2016 Spa2297_RS01130 f7fe6b8ad7ca39cab3f47ddb7a46d9bd 767 Gene3D G3DSA:3.40.50.740 120 193 9.2E-51 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 SMART SM00062 75 303 1.5E-40 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 Gene3D G3DSA:3.40.190.10 161 268 3.5E-17 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 Gene3D G3DSA:3.40.190.10 269 307 1.6E-27 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 Gene3D G3DSA:3.40.190.10 72 160 1.6E-27 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 PANTHER PTHR18966 21 307 6.6E-130 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 PANTHER PTHR18966:SF234 21 307 6.6E-130 T 16-09-2016 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 295 1.7E-44 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 102 115 - T 16-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 Spa2297_RS11285 dd23d31c7559e3f336cd520e85646ded 329 SUPERFAMILY SSF53850 71 295 7.24E-45 T 16-09-2016 Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 Pfam PF08338 Domain of unknown function (DUF1731) 251 296 7.8E-18 T 16-09-2016 IPR013549 Domain of unknown function DUF1731 Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 PANTHER PTHR11092 1 298 7.3E-136 T 16-09-2016 IPR010099 Epimerase family protein SDR39U1 Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 294 2.2E-104 T 16-09-2016 IPR010099 Epimerase family protein SDR39U1 Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 SUPERFAMILY SSF51735 3 286 3.11E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 Gene3D G3DSA:3.40.50.720 4 239 3.8E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 216 3.3E-13 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS09055 75bf3ea662aa1ef2f4b811c2bf217b68 298 PANTHER PTHR11092:SF0 1 298 7.3E-136 T 16-09-2016 Spa2297_RS23230 caa5878b1f84b493cb95105f5b1bc981 107 Pfam PF04248 Domain of unknown function (DUF427) 16 103 8.3E-32 T 16-09-2016 IPR007361 Domain of unknown function DUF427 Spa2297_RS23230 caa5878b1f84b493cb95105f5b1bc981 107 PANTHER PTHR34310 2 102 3.7E-48 T 16-09-2016 Spa2297_RS23230 caa5878b1f84b493cb95105f5b1bc981 107 PANTHER PTHR34310:SF3 2 102 3.7E-48 T 16-09-2016 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 Pfam PF01545 Cation efflux family 27 218 4.1E-47 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 Gene3D G3DSA:3.30.70.1350 226 300 1.7E-4 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 PANTHER PTHR11562 5 308 5.3E-103 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 SUPERFAMILY SSF160240 221 300 1.11E-12 T 16-09-2016 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 PANTHER PTHR11562:SF17 5 308 5.3E-103 T 16-09-2016 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 SUPERFAMILY SSF161111 24 219 9.94E-54 T 16-09-2016 Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 Gene3D G3DSA:1.20.1510.10 25 218 3.3E-59 T 16-09-2016 IPR027469 Cation efflux protein transmembrane domain Spa2297_RS28115 9b0db7447626ac38cb8db86ac41cc478 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 301 6.9E-93 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS22790 b9f14657c76ceff87c4b93023db275b3 289 Pfam PF12730 ABC-2 family transporter protein 41 212 1.2E-7 T 16-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PIRSF PIRSF002936 12 312 1.8E-137 T 16-09-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 21 312 2.9E-137 T 16-09-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293 18 168 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293 254 312 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293 188 221 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293:SF6 18 168 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293:SF6 254 312 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 PANTHER PTHR23293:SF6 188 221 3.1E-75 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 SUPERFAMILY SSF52402 16 219 1.72E-62 T 16-09-2016 Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 Gene3D G3DSA:3.40.50.620 14 220 1.1E-50 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 Gene3D G3DSA:3.40.50.620 253 261 1.1E-50 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS25765 9af1e4416012d7c0d351b126a619aee4 312 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 42 266 2.1E-47 T 16-09-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 Pfam PF08281 Sigma-70, region 4 140 174 8.5E-9 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 SUPERFAMILY SSF88659 120 179 8.6E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 SUPERFAMILY SSF88946 4 103 3.66E-21 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 Gene3D G3DSA:1.10.10.10 119 180 8.7E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 178 5.8E-21 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 PANTHER PTHR30173 8 181 5.6E-26 T 16-09-2016 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 Gene3D G3DSA:1.10.1740.10 6 106 3.5E-23 T 16-09-2016 Spa2297_RS31400 77ac0ac140ba978e77d964d0489b37f8 184 Pfam PF04542 Sigma-70 region 2 30 92 4.7E-13 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 Pfam PF00652 Ricin-type beta-trefoil lectin domain 314 461 1.4E-16 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 SUPERFAMILY SSF50370 311 463 1.29E-22 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 Gene3D G3DSA:2.80.10.50 315 463 6.3E-20 T 16-09-2016 Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 SMART SM00458 312 464 0.0071 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 PANTHER PTHR11675:SF45 311 469 6.2E-54 T 16-09-2016 Spa2297_RS14965 be595574518679b8ce877cd31e3b937a 469 PANTHER PTHR11675 311 469 6.2E-54 T 16-09-2016 Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 SUPERFAMILY SSF46785 12 155 4.86E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 PANTHER PTHR33164 11 155 7.8E-26 T 16-09-2016 Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 PANTHER PTHR33164:SF1 11 155 7.8E-26 T 16-09-2016 Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 Pfam PF12802 MarR family 46 106 5.1E-10 T 16-09-2016 Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 SMART SM00347 41 144 5.5E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11360 166640ef1c49d4c4f4bd4376c1f77fdd 162 Gene3D G3DSA:1.10.10.10 10 155 6.7E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25950 64be2181f32dd7267dcf4d46dd2ad8c3 279 PANTHER PTHR39430 1 275 8.0E-59 T 16-09-2016 Spa2297_RS25950 64be2181f32dd7267dcf4d46dd2ad8c3 279 Pfam PF02517 CAAX protease self-immunity 108 196 8.1E-12 T 16-09-2016 IPR003675 CAAX amino terminal protease GO:0016020 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 PANTHER PTHR30173:SF16 6 190 6.5E-83 T 16-09-2016 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 Pfam PF04542 Sigma-70 region 2 36 100 1.1E-14 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 PANTHER PTHR30173 6 190 6.5E-83 T 16-09-2016 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 Gene3D G3DSA:1.10.1740.10 12 126 1.2E-18 T 16-09-2016 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 Pfam PF08281 Sigma-70, region 4 133 186 2.7E-12 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 SUPERFAMILY SSF88946 10 104 1.57E-18 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 190 1.6E-22 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 Gene3D G3DSA:1.10.10.10 127 191 3.1E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30530 17edd8b87366d6acf41f0e1e2fbcae12 194 SUPERFAMILY SSF88659 125 190 6.32E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126:SF21 123 198 7.2E-82 T 16-09-2016 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126 123 198 7.2E-82 T 16-09-2016 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126:SF21 216 264 7.2E-82 T 16-09-2016 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126 216 264 7.2E-82 T 16-09-2016 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 SUPERFAMILY SSF52799 11 264 1.92E-50 T 16-09-2016 IPR029021 Protein-tyrosine phosphatase-like Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 Gene3D G3DSA:3.90.190.10 13 97 4.4E-19 T 16-09-2016 IPR029021 Protein-tyrosine phosphatase-like Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 Gene3D G3DSA:3.90.190.10 132 191 4.4E-19 T 16-09-2016 IPR029021 Protein-tyrosine phosphatase-like Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126:SF21 1 90 7.2E-82 T 16-09-2016 Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 Pfam PF13350 Tyrosine phosphatase family 11 264 2.8E-64 T 16-09-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type Spa2297_RS28215 4e1fdab56fa7f41fc52f4ac093e46d22 265 PANTHER PTHR31126 1 90 7.2E-82 T 16-09-2016 Spa2297_RS18865 3f0cf0dc52b04355e71fc6bf772a269e 174 PANTHER PTHR23091:SF264 10 173 3.7E-44 T 16-09-2016 Spa2297_RS18865 3f0cf0dc52b04355e71fc6bf772a269e 174 SUPERFAMILY SSF55729 10 172 2.03E-26 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS18865 3f0cf0dc52b04355e71fc6bf772a269e 174 Gene3D G3DSA:3.40.630.30 10 173 1.8E-33 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS18865 3f0cf0dc52b04355e71fc6bf772a269e 174 PANTHER PTHR23091 10 173 3.7E-44 T 16-09-2016 Spa2297_RS18865 3f0cf0dc52b04355e71fc6bf772a269e 174 Pfam PF00583 Acetyltransferase (GNAT) family 69 147 3.9E-11 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 Gene3D G3DSA:3.40.50.720 8 250 3.4E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.4E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.4E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.4E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.4E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 SUPERFAMILY SSF51735 5 261 4.24E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 PANTHER PTHR24322 13 178 8.5E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 Pfam PF00106 short chain dehydrogenase 10 196 6.8E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS01750 2aa82d168ed08c517fc599cc88b08e47 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 5.3E-4 T 16-09-2016 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 Gene3D G3DSA:3.40.50.1770 14 194 4.8E-65 T 16-09-2016 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 PANTHER PTHR10160 13 519 8.9E-252 T 16-09-2016 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 SMART SM01002 154 318 4.5E-69 T 16-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 PIRSF PIRSF000203 12 519 1.0E-220 T 16-09-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 15 41 - T 16-09-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 SMART SM01003 15 145 9.9E-69 T 16-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 149 375 1.7E-64 T 16-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 SUPERFAMILY SSF51735 145 311 2.03E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 13 519 4.7E-209 T 16-09-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 15 145 1.4E-45 T 16-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 SUPERFAMILY SSF52283 13 176 1.96E-53 T 16-09-2016 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 Gene3D G3DSA:3.40.50.1770 195 378 4.8E-40 T 16-09-2016 Spa2297_RS31840 548eae6fc08245a1da053a5db0724e27 523 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 436 519 1.6E-32 T 16-09-2016 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2 Spa2297_RS25160 d496f60ca330ddbe02fbc2ce26629735 132 PANTHER PTHR11803 1 132 5.1E-27 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS25160 d496f60ca330ddbe02fbc2ce26629735 132 Pfam PF01042 Endoribonuclease L-PSP 10 130 4.2E-17 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS25160 d496f60ca330ddbe02fbc2ce26629735 132 Gene3D G3DSA:3.30.1330.40 2 132 8.2E-29 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS25160 d496f60ca330ddbe02fbc2ce26629735 132 SUPERFAMILY SSF55298 7 132 2.83E-26 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Gene3D G3DSA:3.40.1190.10 99 316 1.6E-72 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 455 3.5E-139 T 16-09-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Gene3D G3DSA:3.90.190.20 317 461 3.2E-48 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Pfam PF08245 Mur ligase middle domain 115 294 1.3E-24 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 SUPERFAMILY SSF53623 96 312 2.22E-56 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 SUPERFAMILY SSF51984 10 98 6.15E-26 T 16-09-2016 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 462 38.451 T 16-09-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 SUPERFAMILY SSF53244 314 460 1.47E-41 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 401 8.4E-20 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 PANTHER PTHR23135 5 450 1.1E-183 T 16-09-2016 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Gene3D G3DSA:3.40.50.720 12 98 8.9E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 PANTHER PTHR23135:SF5 5 450 1.1E-183 T 16-09-2016 Spa2297_RS25500 9b525c25cf19e88c33d488adf4ced974 465 Pfam PF01225 Mur ligase family, catalytic domain 13 109 1.9E-27 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.38 T 16-09-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 1.8E-146 T 16-09-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 SUPERFAMILY SSF56327 157 324 1.41E-61 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 Gene3D G3DSA:3.90.110.10 156 326 1.8E-76 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 PIRSF PIRSF000102 2 326 2.7E-61 T 16-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 PANTHER PTHR23382 5 328 4.4E-196 T 16-09-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.4E-31 T 16-09-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 SUPERFAMILY SSF51735 4 156 1.47E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 321 9.0E-35 T 16-09-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 Gene3D G3DSA:3.40.50.720 5 154 5.2E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20360 7ffbaccb24cc1660f0b74cbeae5f5140 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 16-09-2016 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: REACT_474 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 Gene3D G3DSA:1.10.630.10 8 405 1.4E-110 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PANTHER PTHR24286:SF42 22 407 3.9E-148 T 16-09-2016 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PANTHER PTHR24286 22 407 3.9E-148 T 16-09-2016 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 SUPERFAMILY SSF48264 13 405 7.86E-93 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 Pfam PF00067 Cytochrome P450 207 266 2.4E-5 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 Pfam PF00067 Cytochrome P450 278 375 1.5E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00385 P450 superfamily signature 277 288 3.3E-7 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00385 P450 superfamily signature 354 365 3.3E-7 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00385 P450 superfamily signature 242 259 3.3E-7 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00385 P450 superfamily signature 345 354 3.3E-7 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 354 365 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 90 101 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 193 215 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 324 339 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 345 354 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 156 171 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 139 155 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 296 323 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12320 87e825f6a772086b88c51ee85b22df2d 408 PRINTS PR00359 B-class P450 signature 277 288 1.6E-32 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS12140 2d3193ab2ffed2ee3aa991c729cbc434 224 PANTHER PTHR33393 41 222 2.8E-44 T 16-09-2016 Spa2297_RS12140 2d3193ab2ffed2ee3aa991c729cbc434 224 SUPERFAMILY SSF63817 68 221 5.49E-15 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS12140 2d3193ab2ffed2ee3aa991c729cbc434 224 PANTHER PTHR33393:SF4 41 222 2.8E-44 T 16-09-2016 Spa2297_RS12140 2d3193ab2ffed2ee3aa991c729cbc434 224 Gene3D G3DSA:2.40.260.10 77 204 1.3E-5 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS12140 2d3193ab2ffed2ee3aa991c729cbc434 224 Pfam PF04203 Sortase family 77 219 1.4E-17 T 16-09-2016 IPR005754 Sortase family Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 PANTHER PTHR32419 18 331 1.5E-149 T 16-09-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 SUPERFAMILY SSF52833 27 125 3.13E-5 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 SUPERFAMILY SSF47616 157 329 1.81E-32 T 16-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 PIRSF PIRSF015753 9 313 5.1E-102 T 16-09-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 Pfam PF13410 Glutathione S-transferase, C-terminal domain 192 263 1.6E-11 T 16-09-2016 Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 Gene3D G3DSA:1.20.1050.10 165 276 1.8E-20 T 16-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 PANTHER PTHR32419:SF6 18 331 1.5E-149 T 16-09-2016 Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 Gene3D G3DSA:3.40.30.10 25 164 8.4E-13 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29850 5298fb407622918707cf5b734159de82 341 Pfam PF13409 Glutathione S-transferase, N-terminal domain 51 145 4.5E-9 T 16-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 PANTHER PTHR10799 525 1005 3.3E-207 T 16-09-2016 Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 SMART SM00487 534 711 1.1E-26 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 SUPERFAMILY SSF52540 525 742 7.29E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 Pfam PF00176 SNF2 family N-terminal domain 557 812 2.7E-48 T 16-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 PANTHER PTHR10799:SF576 525 1005 3.3E-207 T 16-09-2016 Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 Gene3D G3DSA:3.40.50.300 534 697 4.1E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 SMART SM00490 866 948 1.3E-21 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 Pfam PF12419 SNF2 Helicase protein 366 494 4.7E-35 T 16-09-2016 IPR022138 Helicase SWF/SNF-related Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 Gene3D G3DSA:3.40.50.300 832 981 8.0E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 Pfam PF00271 Helicase conserved C-terminal domain 838 948 8.3E-16 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS26515 767ba7b92bce2c511e11684deaa7391c 1008 SUPERFAMILY SSF52540 750 1004 9.78E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 SMART SM00448 3 114 3.1E-43 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 PANTHER PTHR26402 152 246 1.7E-85 T 16-09-2016 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 SMART SM00862 168 243 1.0E-26 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 Pfam PF00072 Response regulator receiver domain 5 114 4.5E-31 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 PANTHER PTHR26402 3 132 1.7E-85 T 16-09-2016 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 SUPERFAMILY SSF46894 146 245 3.68E-29 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 Gene3D G3DSA:3.40.50.2300 4 125 8.8E-47 T 16-09-2016 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 PANTHER PTHR26402:SF578 3 132 1.7E-85 T 16-09-2016 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 Gene3D G3DSA:1.10.10.10 150 245 3.6E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 PANTHER PTHR26402:SF578 152 246 1.7E-85 T 16-09-2016 Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 SUPERFAMILY SSF52172 3 128 8.25E-42 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS18690 21fc7bd12f9f0575bc2d26b7498ef507 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 243 1.9E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 129 6.3E-28 T 16-09-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 SUPERFAMILY SSF48300 5 65 3.66E-13 T 16-09-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 22.479 T 16-09-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 SUPERFAMILY SSF54736 59 129 2.79E-22 T 16-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 2.6E-45 T 16-09-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 Gene3D G3DSA:3.30.1390.10 57 129 1.2E-30 T 16-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 54 4.4E-17 T 16-09-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 129 4.0E-20 T 16-09-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Spa2297_RS19640 04c5ef6af53b4d0e6d98e0088877876f 129 Gene3D G3DSA:1.20.5.710 3 56 5.9E-18 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 PANTHER PTHR33303:SF3 61 670 3.9E-291 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 361 500 5.3E-37 T 16-09-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 PANTHER PTHR33303 61 670 3.9E-291 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Gene3D G3DSA:3.40.50.261 505 616 7.3E-10 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SUPERFAMILY SSF52210 337 509 5.23E-32 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SUPERFAMILY SSF55729 28 174 1.73E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SUPERFAMILY SSF56059 758 955 2.59E-25 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Pfam PF13549 ATP-grasp domain 753 962 8.5E-54 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Gene3D G3DSA:3.40.630.30 19 183 4.8E-24 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Gene3D G3DSA:3.40.50.720 195 337 6.3E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 PANTHER PTHR33303:SF3 730 963 3.9E-291 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Pfam PF00583 Acetyltransferase (GNAT) family 85 168 4.3E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SMART SM00881 209 308 2.8E-24 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Pfam PF13380 CoA binding domain 214 342 8.3E-15 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 Gene3D G3DSA:3.40.50.261 338 499 5.5E-30 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SUPERFAMILY SSF51735 202 344 3.69E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 PANTHER PTHR33303 730 963 3.9E-291 T 16-09-2016 Spa2297_RS24770 3e2fd76977f1613c90bdd4656f1747bc 979 SUPERFAMILY SSF52210 496 619 1.01E-13 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 630 644 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 770 782 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 713 732 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 696 713 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 552 566 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 592 607 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 675 687 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PRINTS PR00819 CbxX/CfqX superfamily signature 644 663 4.8E-48 T 16-09-2016 IPR000641 CbxX/CfqX GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SUPERFAMILY SSF51126 344 497 3.49E-16 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 221 243 600.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 362 383 2100.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 453 475 5700.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 339 361 7000.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 430 452 94.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 385 406 39.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 151 173 680.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 198 220 5300.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 244 266 5400.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 267 289 4200.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 174 196 530.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 128 150 76.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00710 407 429 6.8 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Gene3D G3DSA:2.160.20.10 388 497 1.8E-9 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Gene3D G3DSA:2.160.20.10 311 387 1.9E-4 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Gene3D G3DSA:2.160.20.10 3 254 5.1E-21 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PANTHER PTHR13779:SF20 552 811 2.0E-96 T 16-09-2016 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SUPERFAMILY SSF51126 205 346 3.41E-8 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 594 724 8.6E-17 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SUPERFAMILY SSF52540 553 792 3.67E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00722 41 172 2.4E-5 T 16-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00722 313 474 9.6E-14 T 16-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SMART SM00382 589 728 7.8E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 PANTHER PTHR13779 552 811 2.0E-96 T 16-09-2016 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Gene3D G3DSA:3.40.50.300 552 742 8.8E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Pfam PF13229 Right handed beta helix region 121 269 2.0E-15 T 16-09-2016 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 Pfam PF13229 Right handed beta helix region 310 461 7.5E-16 T 16-09-2016 Spa2297_RS03410 1cf088ad381990c6304b3d0db68a6096 812 SUPERFAMILY SSF51126 20 241 2.51E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00060 411 485 0.11 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00060 318 392 0.062 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Gene3D G3DSA:2.60.40.10 409 493 4.0E-14 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Gene3D G3DSA:2.60.40.10 316 400 1.3E-13 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SUPERFAMILY SSF49785 22 169 2.48E-25 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Pfam PF00754 F5/8 type C domain 43 164 6.9E-20 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Pfam PF00754 F5/8 type C domain 509 634 1.8E-8 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Pfam PF00754 F5/8 type C domain 183 305 7.9E-20 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SUPERFAMILY SSF49785 175 309 9.92E-26 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SUPERFAMILY SSF51126 1054 1376 5.86E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Gene3D G3DSA:2.60.120.260 33 172 1.7E-31 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Gene3D G3DSA:2.60.120.260 173 314 1.9E-31 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Gene3D G3DSA:2.60.120.260 498 644 1.9E-21 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00231 174 310 2.5E-22 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00231 34 170 2.1E-21 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SUPERFAMILY SSF49265 317 477 7.59E-10 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Pfam PF07705 CARDB 756 861 5.0E-6 T 16-09-2016 IPR011635 CARDB domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 Pfam PF07705 CARDB 643 744 7.0E-23 T 16-09-2016 IPR011635 CARDB domain Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SUPERFAMILY SSF49785 502 639 4.11E-20 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1324 1346 820.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1254 1277 390.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1225 1253 9900.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1357 1381 9700.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1175 1197 17.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1289 1319 3500.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS28685 fbeb9aaf6adc092daa7b0cfcef4d1c9e 1429 SMART SM00710 1199 1221 630.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 Pfam PF01047 MarR family 47 98 5.4E-12 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 6.8E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 6.8E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 6.8E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 SUPERFAMILY SSF46785 20 148 9.69E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 PANTHER PTHR33164 19 157 1.2E-59 T 16-09-2016 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 SMART SM00347 33 133 1.3E-17 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 Gene3D G3DSA:1.10.10.10 20 145 2.2E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01620 6cfc8af5258c91097eac9603d16c6a2f 159 PANTHER PTHR33164:SF2 19 157 1.2E-59 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 SUPERFAMILY SSF55424 357 474 1.15E-28 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 363 468 6.5E-24 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-35 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 1.0E-35 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.0E-35 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 1.0E-35 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 1.0E-35 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 Gene3D G3DSA:3.50.50.60 158 349 1.4E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PANTHER PTHR22912 1 131 1.1E-165 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PANTHER PTHR22912 152 473 1.1E-165 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 Gene3D G3DSA:3.50.50.60 6 157 7.9E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 SUPERFAMILY SSF51905 4 350 2.38E-49 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PIRSF PIRSF000350 1 475 1.2E-75 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 1.0E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 Gene3D G3DSA:3.30.390.30 356 474 1.3E-31 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PANTHER PTHR22912:SF20 1 131 1.1E-165 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PANTHER PTHR22912:SF20 152 473 1.1E-165 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 2.7E-54 T 16-09-2016 Spa2297_RS20825 31e94fd435a15d6250349f9a4472d160 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 2.7E-54 T 16-09-2016 Spa2297_RS30220 f437a178232d00349ae1ff897562c22b 328 PANTHER PTHR21621:SF0 100 310 2.7E-34 T 16-09-2016 Spa2297_RS30220 f437a178232d00349ae1ff897562c22b 328 Gene3D G3DSA:3.40.50.20 3 135 6.2E-4 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS30220 f437a178232d00349ae1ff897562c22b 328 SUPERFAMILY SSF56059 127 309 1.7E-24 T 16-09-2016 Spa2297_RS30220 f437a178232d00349ae1ff897562c22b 328 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 308 6.7E-114 T 16-09-2016 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family Spa2297_RS30220 f437a178232d00349ae1ff897562c22b 328 PANTHER PTHR21621 100 310 2.7E-34 T 16-09-2016 Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 Pfam PF00005 ABC transporter 35 182 1.0E-22 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 PANTHER PTHR24220:SF266 19 281 3.3E-136 T 16-09-2016 Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 SMART SM00382 42 232 6.3E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 Gene3D G3DSA:3.40.50.300 20 254 1.7E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 PANTHER PTHR24220 19 281 3.3E-136 T 16-09-2016 Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 SUPERFAMILY SSF52540 18 246 5.78E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01710 2ccc72dae06dc341af22e0957069919a 286 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 7.8E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 7.8E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 7.8E-6 T 16-09-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 SUPERFAMILY SSF54862 2 60 6.23E-10 T 16-09-2016 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 PANTHER PTHR36923 1 61 2.1E-25 T 16-09-2016 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 2.0E-10 T 16-09-2016 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 Gene3D G3DSA:3.30.70.20 1 61 1.3E-11 T 16-09-2016 Spa2297_RS16620 5ec09f872a530d53d36942abbc00f32c 64 PANTHER PTHR36923:SF1 1 61 2.1E-25 T 16-09-2016 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 306 23.901 T 16-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 Gene3D G3DSA:1.20.1640.10 106 309 5.9E-20 T 16-09-2016 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 Pfam PF02355 Protein export membrane protein 111 304 2.3E-67 T 16-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 SUPERFAMILY SSF82866 103 304 1.2E-29 T 16-09-2016 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 PANTHER PTHR30081 9 334 8.6E-71 T 16-09-2016 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 82 292 7.7E-53 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 295 3.0E-78 T 16-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 Pfam PF07549 SecD/SecF GG Motif 41 60 2.1E-4 T 16-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 5.7E-22 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 PRINTS PR01755 Bacterial translocase SecF protein signature 203 221 5.7E-22 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 PRINTS PR01755 Bacterial translocase SecF protein signature 155 169 5.7E-22 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS05735 59855d9197e17277978db7f4625855b1 373 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 5.7E-22 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Pfam PF00990 Diguanylate cyclase, GGDEF domain 424 546 2.8E-31 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SUPERFAMILY SSF55073 424 549 2.51E-35 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 PANTHER PTHR10799:SF774 426 545 1.1E-30 T 16-09-2016 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SMART SM00091 217 287 1.1E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Gene3D G3DSA:3.30.70.270 342 367 3.4E-46 T 16-09-2016 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Gene3D G3DSA:3.30.70.270 422 549 3.4E-46 T 16-09-2016 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Gene3D G3DSA:3.30.450.20 209 326 9.6E-20 T 16-09-2016 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SMART SM00065 29 199 1.6E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Gene3D G3DSA:3.30.450.40 10 194 3.9E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 Pfam PF13426 PAS domain 238 326 3.3E-7 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 424 546 6.1E-29 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SUPERFAMILY SSF55781 13 211 1.83E-15 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SMART SM00086 287 329 0.007 T 16-09-2016 IPR001610 PAC motif Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 213 335 2.8E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 PANTHER PTHR10799 426 545 1.1E-30 T 16-09-2016 Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SMART SM00267 329 553 3.0E-28 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS14870 75527e52bbf1ade60f27df46e19cff04 554 SUPERFAMILY SSF55785 205 325 3.66E-18 T 16-09-2016 IPR000014 PAS domain Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 Gene3D G3DSA:3.30.70.660 121 257 7.5E-37 T 16-09-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 SUPERFAMILY SSF55120 9 265 5.47E-71 T 16-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 PIRSF PIRSF001430 10 276 4.7E-74 T 16-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 253 6.3E-50 T 16-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 PANTHER PTHR11142 2 265 2.1E-82 T 16-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 259 31.353 T 16-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 Pfam PF01416 tRNA pseudouridine synthase 17 110 2.5E-5 T 16-09-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 Pfam PF01416 tRNA pseudouridine synthase 158 260 1.3E-22 T 16-09-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 Gene3D G3DSA:3.30.70.580 10 119 3.3E-32 T 16-09-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS19940 04c9b684caa8bf2b35f5c5ff37c0befa 284 PANTHER PTHR11142:SF0 2 265 2.1E-82 T 16-09-2016 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 Pfam PF12704 MacB-like periplasmic core domain 19 235 9.8E-12 T 16-09-2016 IPR025857 MacB-like periplasmic core domain Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 Pfam PF12704 MacB-like periplasmic core domain 497 696 4.1E-10 T 16-09-2016 IPR025857 MacB-like periplasmic core domain Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 PANTHER PTHR30489 243 854 0.0 T 16-09-2016 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 PANTHER PTHR30489:SF9 1 196 0.0 T 16-09-2016 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 PANTHER PTHR30489 1 196 0.0 T 16-09-2016 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 PANTHER PTHR30489:SF9 243 854 0.0 T 16-09-2016 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 Pfam PF02687 FtsX-like permease family 272 392 2.9E-24 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS13500 50a9457648f3057d309f132a50be8b92 854 Pfam PF02687 FtsX-like permease family 731 846 4.8E-19 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS21945 2221339615f8b4f2ca010fb920b817b6 226 Pfam PF01987 Mitochondrial biogenesis AIM24 18 214 2.8E-37 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS21945 2221339615f8b4f2ca010fb920b817b6 226 PANTHER PTHR31801:SF0 7 225 6.0E-92 T 16-09-2016 Spa2297_RS21945 2221339615f8b4f2ca010fb920b817b6 226 PANTHER PTHR31801 7 225 6.0E-92 T 16-09-2016 Spa2297_RS21945 2221339615f8b4f2ca010fb920b817b6 226 SUPERFAMILY SSF51219 16 216 3.14E-49 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS21945 2221339615f8b4f2ca010fb920b817b6 226 Gene3D G3DSA:3.60.160.10 13 216 3.6E-43 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS14085 b7c68286ac73eb480a92a7afd0719ca3 365 PIRSF PIRSF005508 2 357 1.1E-135 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS14085 b7c68286ac73eb480a92a7afd0719ca3 365 PANTHER PTHR10361:SF31 2 348 5.7E-158 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS14085 b7c68286ac73eb480a92a7afd0719ca3 365 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 14 343 2.6E-131 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS14085 b7c68286ac73eb480a92a7afd0719ca3 365 Pfam PF01758 Sodium Bile acid symporter family 59 254 1.3E-61 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS14085 b7c68286ac73eb480a92a7afd0719ca3 365 PANTHER PTHR10361 2 348 5.7E-158 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS20705 6c8e0dac38c56c2ecff9ed5d0383624d 194 PANTHER PTHR35400 1 194 1.8E-30 T 16-09-2016 Spa2297_RS20705 6c8e0dac38c56c2ecff9ed5d0383624d 194 Gene3D G3DSA:3.90.1570.10 24 146 9.6E-16 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS20705 6c8e0dac38c56c2ecff9ed5d0383624d 194 PANTHER PTHR35400:SF1 1 194 1.8E-30 T 16-09-2016 Spa2297_RS20705 6c8e0dac38c56c2ecff9ed5d0383624d 194 SUPERFAMILY SSF52980 24 147 6.43E-17 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS20705 6c8e0dac38c56c2ecff9ed5d0383624d 194 Pfam PF05685 Putative restriction endonuclease 25 186 2.7E-19 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS20790 03b08ddd0a0f1b38806aabac4ffc9bd3 297 Pfam PF00171 Aldehyde dehydrogenase family 23 254 1.2E-39 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20790 03b08ddd0a0f1b38806aabac4ffc9bd3 297 PANTHER PTHR11699:SF165 1 254 1.0E-113 T 16-09-2016 Spa2297_RS20790 03b08ddd0a0f1b38806aabac4ffc9bd3 297 PANTHER PTHR11699 1 254 1.0E-113 T 16-09-2016 Spa2297_RS20790 03b08ddd0a0f1b38806aabac4ffc9bd3 297 SUPERFAMILY SSF53720 6 255 1.28E-45 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20790 03b08ddd0a0f1b38806aabac4ffc9bd3 297 Gene3D G3DSA:3.40.605.10 5 254 9.1E-56 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 Gene3D G3DSA:1.20.1250.20 208 381 1.1E-12 T 16-09-2016 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 SUPERFAMILY SSF103473 14 390 3.92E-42 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 Gene3D G3DSA:1.20.1250.20 18 189 1.2E-18 T 16-09-2016 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 Pfam PF07690 Major Facilitator Superfamily 20 198 9.9E-17 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 Pfam PF07690 Major Facilitator Superfamily 217 390 9.2E-10 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 PANTHER PTHR23514:SF13 2 402 2.9E-152 T 16-09-2016 Spa2297_RS05460 73bc9b132b81e2aaf36eb409bbdc2bf6 403 PANTHER PTHR23514 2 402 2.9E-152 T 16-09-2016 Spa2297_RS22955 28d60a3d76771472761c3fb0932f67ef 318 Gene3D G3DSA:1.10.3720.10 35 310 2.9E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22955 28d60a3d76771472761c3fb0932f67ef 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 310 3.4E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22955 28d60a3d76771472761c3fb0932f67ef 318 PANTHER PTHR30406 2 318 9.1E-125 T 16-09-2016 Spa2297_RS22955 28d60a3d76771472761c3fb0932f67ef 318 PANTHER PTHR30406:SF2 2 318 9.1E-125 T 16-09-2016 Spa2297_RS22955 28d60a3d76771472761c3fb0932f67ef 318 SUPERFAMILY SSF161098 83 308 4.19E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS16670 a285ea61538daf97774985d781931418 329 Gene3D G3DSA:3.60.10.10 99 263 2.1E-6 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS16670 a285ea61538daf97774985d781931418 329 SUPERFAMILY SSF56219 98 328 1.7E-24 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS16670 a285ea61538daf97774985d781931418 329 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 103 320 2.9E-17 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.420.10 315 412 4.0E-46 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.420.10 257 279 4.0E-46 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 SUPERFAMILY SSF48113 435 737 3.54E-108 T 16-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 32 738 0.0 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.420.10 591 713 1.1E-43 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PANTHER PTHR30555:SF0 1 737 0.0 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 16-09-2016 IPR019793 Peroxidases heam-ligand binding site Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 16-09-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 1.4E-19 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 1.4E-19 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 1.4E-19 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 1.4E-19 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00458 Haem peroxidase superfamily signature 323 338 1.4E-19 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 SUPERFAMILY SSF48113 29 435 5.6E-155 T 16-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Pfam PF00141 Peroxidase 407 712 1.9E-37 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Pfam PF00141 Peroxidase 94 400 1.2E-48 T 16-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.520.10 437 590 1.5E-61 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.520.10 244 256 3.1E-72 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.520.10 57 211 3.1E-72 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Gene3D G3DSA:1.10.520.10 716 737 1.5E-61 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PANTHER PTHR30555 1 737 0.0 T 16-09-2016 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 Hamap MF_01961 Catalase-peroxidase [katG]. 15 738 41.796 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 1.2E-50 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 1.2E-50 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 1.2E-50 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 485 511 1.2E-50 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS30785 2a89a3bc57c4be4648294eba5575d11f 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 1.2E-50 T 16-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 PANTHER PTHR33434:SF2 3 281 1.2E-88 T 16-09-2016 Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 Gene3D G3DSA:3.40.50.10170 5 150 8.3E-44 T 16-09-2016 Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 PANTHER PTHR33434 3 281 1.2E-88 T 16-09-2016 Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 SUPERFAMILY SSF82549 5 279 6.28E-77 T 16-09-2016 Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 1.4E-87 T 16-09-2016 IPR003797 DegV Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 279 4.6E-89 T 16-09-2016 IPR003797 DegV Spa2297_RS10835 1b4ecd5c704e6b050990072dabb32ad6 281 Gene3D G3DSA:3.30.1180.10 155 279 1.3E-42 T 16-09-2016 Spa2297_RS27245 3e93a365bd30ae3932a17441e5176517 101 SUPERFAMILY SSF55248 3 95 8.76E-24 T 16-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 Spa2297_RS27245 3e93a365bd30ae3932a17441e5176517 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 93 4.0E-23 T 16-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 Spa2297_RS27245 3e93a365bd30ae3932a17441e5176517 101 PANTHER PTHR12599 3 98 4.3E-24 T 16-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 Spa2297_RS27245 3e93a365bd30ae3932a17441e5176517 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 3 95 20.162 T 16-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 Spa2297_RS27245 3e93a365bd30ae3932a17441e5176517 101 Gene3D G3DSA:3.30.1360.20 2 96 3.7E-23 T 16-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 Spa2297_RS25710 feac9acbb3178164eaa2adac0ca0d40f 277 PANTHER PTHR32243 1 277 3.6E-138 T 16-09-2016 Spa2297_RS25710 feac9acbb3178164eaa2adac0ca0d40f 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 265 5.2E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25710 feac9acbb3178164eaa2adac0ca0d40f 277 Gene3D G3DSA:1.10.3720.10 6 264 5.7E-68 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25710 feac9acbb3178164eaa2adac0ca0d40f 277 PANTHER PTHR32243:SF42 1 277 3.6E-138 T 16-09-2016 Spa2297_RS25710 feac9acbb3178164eaa2adac0ca0d40f 277 SUPERFAMILY SSF161098 5 276 2.15E-71 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 Gene3D G3DSA:3.40.190.10 181 218 1.5E-5 T 16-09-2016 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 PANTHER PTHR30346:SF7 6 314 2.5E-101 T 16-09-2016 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 SUPERFAMILY SSF53850 112 300 2.17E-11 T 16-09-2016 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 Gene3D G3DSA:3.40.190.10 114 180 1.6E-9 T 16-09-2016 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 SUPERFAMILY SSF46785 8 91 9.64E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 PANTHER PTHR30346 6 314 2.5E-101 T 16-09-2016 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.5E-20 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 Gene3D G3DSA:1.10.10.10 7 86 8.4E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 6.7E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 6.7E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 6.7E-10 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS12805 22c296348ba8a9ab3f30002a24412fb8 323 Pfam PF03466 LysR substrate binding domain 110 225 3.7E-9 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 Gene3D G3DSA:3.40.1160.10 12 245 5.3E-81 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 Hamap MF_01220_B Uridylate kinase [pyrH]. 12 246 42.349 T 16-09-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 16 245 1.3E-89 T 16-09-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 Pfam PF00696 Amino acid kinase family 18 224 3.2E-24 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 SUPERFAMILY SSF53633 16 245 4.45E-68 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 PIRSF PIRSF005650 11 251 5.2E-87 T 16-09-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 PANTHER PTHR21499 16 248 1.4E-108 T 16-09-2016 Spa2297_RS23830 dd561f84b08b09a4a754a716eab44122 252 PANTHER PTHR21499:SF23 16 248 1.4E-108 T 16-09-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 Spa2297_RS08810 a6a7b91c57b115e95bf986e1eccb193c 93 PANTHER PTHR30154:SF12 2 81 2.8E-19 T 16-09-2016 Spa2297_RS08810 a6a7b91c57b115e95bf986e1eccb193c 93 SUPERFAMILY SSF54909 3 78 2.01E-18 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS08810 a6a7b91c57b115e95bf986e1eccb193c 93 PANTHER PTHR30154 2 81 2.8E-19 T 16-09-2016 Spa2297_RS08810 a6a7b91c57b115e95bf986e1eccb193c 93 Gene3D G3DSA:3.30.70.920 3 78 3.1E-25 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS08810 a6a7b91c57b115e95bf986e1eccb193c 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 7.4E-16 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 PANTHER PTHR33280 2 66 3.6E-32 T 16-09-2016 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 28.907 T 16-09-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 2.1E-20 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 2.1E-20 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.1E-20 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 Pfam PF01197 Ribosomal protein L31 2 66 7.3E-30 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 SUPERFAMILY SSF143800 1 67 5.1E-24 T 16-09-2016 Spa2297_RS22630 2ccf2d2d0f6117871ccf908f0c253394 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 8.4E-33 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04555 70f72bfe3fa98cc455e13d0bb98af7ec 141 Gene3D G3DSA:3.40.630.30 3 135 1.9E-30 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04555 70f72bfe3fa98cc455e13d0bb98af7ec 141 PANTHER PTHR23091 1 138 9.6E-30 T 16-09-2016 Spa2297_RS04555 70f72bfe3fa98cc455e13d0bb98af7ec 141 Pfam PF00583 Acetyltransferase (GNAT) family 51 126 4.1E-14 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS04555 70f72bfe3fa98cc455e13d0bb98af7ec 141 SUPERFAMILY SSF55729 1 135 1.96E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS04555 70f72bfe3fa98cc455e13d0bb98af7ec 141 PANTHER PTHR23091:SF276 1 138 9.6E-30 T 16-09-2016 Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 Gene3D G3DSA:3.20.20.60 7 253 3.5E-79 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 PANTHER PTHR32308 7 317 2.1E-203 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 12 242 6.6E-47 T 16-09-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 SUPERFAMILY SSF51621 8 253 6.8E-66 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 PANTHER PTHR32308:SF2 7 317 2.1E-203 T 16-09-2016 Spa2297_RS26925 6d680e255ca5d42bb96ddc089a0efd99 321 PIRSF PIRSF015582 1 320 3.8E-94 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 PRINTS PR00364 Disease resistance protein signature 107 121 3.7E-7 T 16-09-2016 Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 PRINTS PR00364 Disease resistance protein signature 204 218 3.7E-7 T 16-09-2016 Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 PRINTS PR00364 Disease resistance protein signature 40 55 3.7E-7 T 16-09-2016 Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 SUPERFAMILY SSF52540 7 237 2.86E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 Gene3D G3DSA:1.25.40.10 442 645 2.8E-16 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05685 2acabed8cf22e67af1d06b522f1c9feb 728 SUPERFAMILY SSF48452 482 623 1.68E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 9.4E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 PANTHER PTHR26402:SF151 2 215 3.6E-94 T 16-09-2016 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 SMART SM00448 2 117 4.1E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 Gene3D G3DSA:3.40.50.2300 2 125 1.4E-39 T 16-09-2016 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 SMART SM00421 152 209 1.6E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 SUPERFAMILY SSF46894 148 215 1.46E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.5E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.5E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.5E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 Pfam PF00072 Response regulator receiver domain 4 117 2.8E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 Gene3D G3DSA:1.10.10.10 126 216 1.5E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 SUPERFAMILY SSF52172 2 135 3.56E-34 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS03545 716d200fc193fb60dd57f3fbd83fd95f 221 PANTHER PTHR26402 2 215 3.6E-94 T 16-09-2016 Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 16-09-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 SUPERFAMILY SSF53254 1 196 3.46E-40 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 Gene3D G3DSA:3.40.50.1240 1 190 8.4E-40 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 SMART SM00855 2 156 9.6E-18 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 195 2.0E-42 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS10240 dd1d60b560ff857c3637c635e5cf9614 222 PANTHER PTHR23029 1 195 6.3E-35 T 16-09-2016 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 Gene3D G3DSA:3.20.20.120 130 423 7.6E-139 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 142 422 8.7E-135 T 16-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PIRSF PIRSF001400 3 424 9.7E-189 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PANTHER PTHR11902 4 421 2.7E-269 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 SUPERFAMILY SSF54826 6 140 9.22E-52 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 Pfam PF03952 Enolase, N-terminal domain 6 136 2.2E-54 T 16-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 SUPERFAMILY SSF51604 140 424 1.31E-133 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 16-09-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 334 348 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 39 53 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 163 176 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 311 322 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 363 380 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 PRINTS PR00148 Enolase signature 109 125 5.8E-47 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 6 425 1.8E-205 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 Hamap MF_00318 Enolase [eno]. 4 411 45.345 T 16-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 SMART SM01192 141 425 2.7E-228 T 16-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 SMART SM01193 6 136 4.7E-86 T 16-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 Spa2297_RS13445 54ab30179f95458a6a7f80e66598ab26 428 Gene3D G3DSA:3.30.390.10 6 127 1.6E-51 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS19190 8dcec59be93134e9c7250cbb69e10916 254 Gene3D G3DSA:3.90.1720.10 135 253 1.3E-38 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS19190 8dcec59be93134e9c7250cbb69e10916 254 SUPERFAMILY SSF54001 135 253 4.41E-37 T 16-09-2016 Spa2297_RS19190 8dcec59be93134e9c7250cbb69e10916 254 PANTHER PTHR21666 124 238 1.1E-24 T 16-09-2016 Spa2297_RS19190 8dcec59be93134e9c7250cbb69e10916 254 Pfam PF00877 NlpC/P60 family 152 238 2.7E-21 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 1.7E-45 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 SUPERFAMILY SSF51735 1 156 1.01E-44 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 SUPERFAMILY SSF56327 165 418 4.58E-63 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 397 6.3E-42 T 16-09-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 Gene3D G3DSA:3.40.50.720 1 158 2.1E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PANTHER PTHR32092:SF5 1 420 4.7E-195 T 16-09-2016 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 1.5E-35 T 16-09-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 Gene3D G3DSA:3.90.110.10 162 418 6.7E-86 T 16-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Spa2297_RS11270 63e58aafe18cefd4d50d81d494b97df0 421 PANTHER PTHR32092 1 420 4.7E-195 T 16-09-2016 Spa2297_RS12435 0919bedc7cd5d6fa750a7f78c9c22f3c 416 PANTHER PTHR30009 19 409 1.0E-169 T 16-09-2016 Spa2297_RS12435 0919bedc7cd5d6fa750a7f78c9c22f3c 416 PANTHER PTHR30009:SF2 19 409 1.0E-169 T 16-09-2016 Spa2297_RS12435 0919bedc7cd5d6fa750a7f78c9c22f3c 416 Pfam PF02378 Phosphotransferase system, EIIC 27 337 1.3E-71 T 16-09-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 Spa2297_RS22890 b71ddd82a63a11e0026c34bbd15ddd3a 112 Pfam PF12823 Domain of unknown function (DUF3817) 6 96 6.3E-29 T 16-09-2016 IPR023845 Domain of unknown function DUF3817, transmembrane Spa2297_RS22890 b71ddd82a63a11e0026c34bbd15ddd3a 112 PANTHER PTHR40077 1 112 2.2E-30 T 16-09-2016 Spa2297_RS22890 b71ddd82a63a11e0026c34bbd15ddd3a 112 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 94 2.8E-27 T 16-09-2016 IPR023845 Domain of unknown function DUF3817, transmembrane Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 Gene3D G3DSA:2.40.30.10 6 143 2.1E-33 T 16-09-2016 Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 Pfam PF08021 Siderophore-interacting FAD-binding domain 15 145 9.8E-41 T 16-09-2016 IPR013113 FAD-binding 9, siderophore-interacting Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 PANTHER PTHR30157:SF0 1 286 3.6E-125 T 16-09-2016 Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 PANTHER PTHR30157 1 286 3.6E-125 T 16-09-2016 Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 Pfam PF04954 Siderophore-interacting protein 160 276 4.1E-39 T 16-09-2016 IPR007037 Siderophore-interacting protein Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 SUPERFAMILY SSF63380 6 143 3.12E-10 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS11780 30a13fb55f806b2ee38ddfd9957b11e0 286 Gene3D G3DSA:3.40.50.80 153 284 4.0E-48 T 16-09-2016 Spa2297_RS21695 7cfe889d18ae5be0dad91fe403c6eed2 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 2.9E-29 T 16-09-2016 IPR021465 Protein of unknown function DUF3117 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 Pfam PF00326 Prolyl oligopeptidase family 502 702 4.0E-45 T 16-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 PANTHER PTHR11731 83 704 2.6E-136 T 16-09-2016 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 543 573 - T 16-09-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 SUPERFAMILY SSF82171 129 344 3.53E-33 T 16-09-2016 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 SUPERFAMILY SSF82171 18 67 3.53E-33 T 16-09-2016 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 Gene3D G3DSA:2.140.10.30 20 439 1.8E-65 T 16-09-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 Gene3D G3DSA:3.40.50.1820 456 703 2.6E-76 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 113 412 1.6E-33 T 16-09-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 PANTHER PTHR11731 18 42 2.6E-136 T 16-09-2016 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 SUPERFAMILY SSF53474 460 703 3.62E-60 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 PANTHER PTHR11731:SF110 18 42 2.6E-136 T 16-09-2016 Spa2297_RS21610 ec89887d89e03d985e6ca14c54fcf178 707 PANTHER PTHR11731:SF110 83 704 2.6E-136 T 16-09-2016 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 PANTHER PTHR11695 17 361 1.5E-198 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 SUPERFAMILY SSF51735 154 323 2.93E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 Gene3D G3DSA:3.90.180.10 4 182 5.9E-56 T 16-09-2016 IPR011032 GroES-like Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 PANTHER PTHR11695:SF417 17 361 1.5E-198 T 16-09-2016 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 5.6E-196 T 16-09-2016 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 Gene3D G3DSA:3.40.50.720 183 302 4.1E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 9.3E-27 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 SMART SM00829 14 361 4.5E-5 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 SUPERFAMILY SSF50129 4 186 3.04E-54 T 16-09-2016 IPR011032 GroES-like Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 SUPERFAMILY SSF50129 310 360 1.08E-5 T 16-09-2016 IPR011032 GroES-like Spa2297_RS05210 7fdc5e62f31cd8d0c1320dc1e6590607 361 Pfam PF00107 Zinc-binding dehydrogenase 190 315 2.8E-28 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS07815 04a06b174a3b42b2123c88f44ec27b17 349 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 1.8E-80 T 16-09-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA Spa2297_RS07815 04a06b174a3b42b2123c88f44ec27b17 349 PANTHER PTHR38658 1 312 7.6E-102 T 16-09-2016 Spa2297_RS07815 04a06b174a3b42b2123c88f44ec27b17 349 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 300 6.5E-93 T 16-09-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA Spa2297_RS07815 04a06b174a3b42b2123c88f44ec27b17 349 PANTHER PTHR38658:SF1 1 312 7.6E-102 T 16-09-2016 Spa2297_RS23310 2964e2f12008992b072c7bf2a11dbe92 400 Pfam PF07995 Glucose / Sorbosone dehydrogenase 84 384 2.2E-70 T 16-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 Spa2297_RS23310 2964e2f12008992b072c7bf2a11dbe92 400 Gene3D G3DSA:2.120.10.30 69 397 1.7E-88 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS23310 2964e2f12008992b072c7bf2a11dbe92 400 SUPERFAMILY SSF50952 68 384 2.88E-46 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS23310 2964e2f12008992b072c7bf2a11dbe92 400 PANTHER PTHR19328 77 297 5.2E-68 T 16-09-2016 Spa2297_RS00665 96a62548b7cf0472b15fd43125e36b1f 258 Pfam PF13490 Putative zinc-finger 12 39 4.5E-7 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS00665 96a62548b7cf0472b15fd43125e36b1f 258 PANTHER PTHR37461 1 258 1.3E-27 T 16-09-2016 Spa2297_RS00665 96a62548b7cf0472b15fd43125e36b1f 258 PANTHER PTHR37461:SF1 1 258 1.3E-27 T 16-09-2016 Spa2297_RS00665 96a62548b7cf0472b15fd43125e36b1f 258 Pfam PF10099 Anti-sigma-K factor rskA 60 251 4.6E-31 T 16-09-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 Gene3D G3DSA:3.40.50.720 165 283 5.1E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 Pfam PF00107 Zinc-binding dehydrogenase 173 298 1.6E-23 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 Gene3D G3DSA:3.90.180.10 1 164 5.8E-35 T 16-09-2016 IPR011032 GroES-like Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 SUPERFAMILY SSF50129 1 161 2.43E-39 T 16-09-2016 IPR011032 GroES-like Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 SMART SM00829 7 336 0.0035 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 PANTHER PTHR11695 12 338 3.0E-138 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 PANTHER PTHR11695:SF601 12 338 3.0E-138 T 16-09-2016 Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 SUPERFAMILY SSF51735 143 305 4.85E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03270 f994fbe2c5a355867f10cef3934bc57f 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 122 5.7E-21 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 Gene3D G3DSA:3.40.50.720 178 278 6.8E-24 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 4.0E-30 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 Gene3D G3DSA:3.90.180.10 1 177 1.8E-50 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 PANTHER PTHR11695 13 345 1.9E-104 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 PANTHER PTHR11695:SF280 13 345 1.9E-104 T 16-09-2016 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 SMART SM00829 10 342 2.3E-6 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 SUPERFAMILY SSF51735 142 312 2.63E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 Pfam PF00107 Zinc-binding dehydrogenase 182 305 1.3E-20 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS01890 f179c6665c22ec5e9e2e5d238f31854c 346 SUPERFAMILY SSF50129 1 179 4.39E-45 T 16-09-2016 IPR011032 GroES-like Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 SUPERFAMILY SSF46689 16 81 2.46E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 PANTHER PTHR30328:SF4 1 193 2.9E-45 T 16-09-2016 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.5E-17 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 SUPERFAMILY SSF48498 90 193 4.78E-10 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 Gene3D G3DSA:1.10.357.10 17 196 1.7E-29 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.3E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.3E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS23425 7a1a65da27136314eb97471972a4bbc6 206 PANTHER PTHR30328 1 193 2.9E-45 T 16-09-2016 Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 SUPERFAMILY SSF56784 17 285 2.76E-54 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 20 281 3.5E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 PANTHER PTHR10000:SF8 2 287 2.5E-73 T 16-09-2016 Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 Gene3D G3DSA:3.40.50.1000 16 87 5.3E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 Gene3D G3DSA:3.40.50.1000 189 285 5.3E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16270 8c9452d48f7b059981ba3a0bc1d84c78 289 PANTHER PTHR10000 2 287 2.5E-73 T 16-09-2016 Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 PANTHER PTHR30055:SF60 1 157 9.9E-35 T 16-09-2016 Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 61 1.9E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 SUPERFAMILY SSF48498 88 187 1.04E-8 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 Gene3D G3DSA:1.10.357.10 14 188 1.6E-22 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 PANTHER PTHR30055 1 157 9.9E-35 T 16-09-2016 Spa2297_RS06020 52f7b067f0ac5d437c3d515314471196 192 SUPERFAMILY SSF46689 13 71 3.45E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 Gene3D G3DSA:3.40.50.720 7 246 5.3E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 SUPERFAMILY SSF51735 5 243 7.54E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03630 87fa5f8582e2ebb5f6b4230b5a3685c1 248 Pfam PF00106 short chain dehydrogenase 10 179 9.5E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 Gene3D G3DSA:3.40.250.10 1 152 1.6E-43 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 Gene3D G3DSA:3.40.250.10 157 281 2.4E-34 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 SMART SM00450 6 138 7.8E-21 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 SMART SM00450 155 274 4.2E-13 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 SUPERFAMILY SSF52821 4 152 2.75E-35 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 Pfam PF00581 Rhodanese-like domain 6 132 6.0E-17 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 Pfam PF00581 Rhodanese-like domain 171 270 1.2E-8 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 PANTHER PTHR11364 1 280 1.0E-87 T 16-09-2016 Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 ProSitePatterns PS00380 Rhodanese signature 1. 46 57 - T 16-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 PANTHER PTHR11364:SF0 1 280 1.0E-87 T 16-09-2016 Spa2297_RS24795 fa658ee70ee607b675f60203a72ec062 283 SUPERFAMILY SSF52821 165 280 1.83E-28 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS05745 5b75429737044f75b16d81aa306dfebb 168 SMART SM01323 1 82 3.2E-23 T 16-09-2016 IPR003849 Preprotein translocase YajC Spa2297_RS05745 5b75429737044f75b16d81aa306dfebb 168 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 82 1.2E-15 T 16-09-2016 IPR003849 Preprotein translocase YajC Spa2297_RS05745 5b75429737044f75b16d81aa306dfebb 168 PANTHER PTHR33909 1 106 1.8E-28 T 16-09-2016 Spa2297_RS05745 5b75429737044f75b16d81aa306dfebb 168 PANTHER PTHR33909:SF1 1 106 1.8E-28 T 16-09-2016 Spa2297_RS05745 5b75429737044f75b16d81aa306dfebb 168 Pfam PF02699 Preprotein translocase subunit 5 79 6.1E-17 T 16-09-2016 IPR003849 Preprotein translocase YajC Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 SUPERFAMILY SSF51445 72 276 8.42E-65 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 Gene3D G3DSA:3.20.20.80 72 276 1.9E-70 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 76 109 - T 16-09-2016 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 Pfam PF01183 Glycosyl hydrolases family 25 75 259 8.4E-55 T 16-09-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 SMART SM00641 72 181 4.4E-46 T 16-09-2016 IPR018077 Glycoside hydrolase, family 25 subgroup Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 PANTHER PTHR34135 44 267 2.4E-84 T 16-09-2016 Spa2297_RS30685 189ae5369d92434d01615f30979ad4b9 277 PANTHER PTHR34135:SF2 44 267 2.4E-84 T 16-09-2016 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 162 1.7E-37 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 PANTHER PTHR22981 1 286 5.5E-67 T 16-09-2016 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 SUPERFAMILY SSF48179 167 288 3.06E-21 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 Gene3D G3DSA:3.40.50.720 3 166 4.6E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 1.5E-12 T 16-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 Gene3D G3DSA:1.10.1040.10 168 286 1.8E-25 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 SUPERFAMILY SSF51735 6 163 6.03E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29100 a1e6046ae21d3626ed3086f970291916 296 PIRSF PIRSF000103 1 296 2.1E-84 T 16-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Spa2297_RS19630 dd7f3d272df74ec968f6ecf968e44644 281 SUPERFAMILY SSF89392 33 261 1.14E-30 T 16-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spa2297_RS09735 07192b9c46b6894561b373fb34261313 196 Gene3D G3DSA:3.40.50.850 10 193 1.0E-42 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS09735 07192b9c46b6894561b373fb34261313 196 PANTHER PTHR11080 1 192 3.2E-65 T 16-09-2016 Spa2297_RS09735 07192b9c46b6894561b373fb34261313 196 Pfam PF00857 Isochorismatase family 22 191 1.2E-27 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS09735 07192b9c46b6894561b373fb34261313 196 PANTHER PTHR11080:SF17 1 192 3.2E-65 T 16-09-2016 Spa2297_RS09735 07192b9c46b6894561b373fb34261313 196 SUPERFAMILY SSF52499 8 193 6.15E-42 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS26610 8d397ab96fafeef49d8771ba01c2123b 303 Gene3D G3DSA:2.60.120.620 9 262 1.1E-51 T 16-09-2016 Spa2297_RS26610 8d397ab96fafeef49d8771ba01c2123b 303 PANTHER PTHR20883 1 268 1.1E-30 T 16-09-2016 Spa2297_RS26610 8d397ab96fafeef49d8771ba01c2123b 303 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 82 249 4.8E-21 T 16-09-2016 IPR008775 Phytanoyl-CoA dioxygenase Spa2297_RS26610 8d397ab96fafeef49d8771ba01c2123b 303 SUPERFAMILY SSF51197 17 263 2.84E-50 T 16-09-2016 Spa2297_RS14250 7f96dbd6ce73dbe93f31725521e89457 136 PANTHER PTHR21366:SF12 1 134 4.0E-56 T 16-09-2016 Spa2297_RS14250 7f96dbd6ce73dbe93f31725521e89457 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 131 7.1E-15 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS14250 7f96dbd6ce73dbe93f31725521e89457 136 Gene3D G3DSA:3.10.180.10 2 134 4.2E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14250 7f96dbd6ce73dbe93f31725521e89457 136 SUPERFAMILY SSF54593 3 134 5.24E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14250 7f96dbd6ce73dbe93f31725521e89457 136 PANTHER PTHR21366 1 134 4.0E-56 T 16-09-2016 Spa2297_RS22710 ac4e832e6b496bbca0f551334c91b3be 148 Pfam PF10739 Protein of unknown function (DUF2550) 12 142 1.9E-45 T 16-09-2016 IPR019675 Protein of unknown function DUF2550 Spa2297_RS16175 af6414bb723fdfc9d3c5cf72ef86019b 154 SUPERFAMILY SSF55874 30 132 7.99E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16175 af6414bb723fdfc9d3c5cf72ef86019b 154 Gene3D G3DSA:3.30.565.10 27 140 8.0E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16175 af6414bb723fdfc9d3c5cf72ef86019b 154 Pfam PF13581 Histidine kinase-like ATPase domain 13 132 1.3E-22 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16175 af6414bb723fdfc9d3c5cf72ef86019b 154 PANTHER PTHR35526 16 152 2.2E-15 T 16-09-2016 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 PANTHER PTHR11751:SF398 9 367 1.7E-116 T 16-09-2016 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 363 4.9E-97 T 16-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 16-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 Gene3D G3DSA:3.40.640.10 46 270 6.8E-64 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 Gene3D G3DSA:3.90.1150.10 271 365 8.7E-19 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 PANTHER PTHR11751 9 367 1.7E-116 T 16-09-2016 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 SUPERFAMILY SSF53383 28 361 1.9E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 364 54.272 T 16-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 Spa2297_RS08375 bf7e5310597f59c3b34b685c8249c887 369 Pfam PF00155 Aminotransferase class I and II 29 360 2.9E-68 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 SMART SM00636 51 404 1.6E-118 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 Gene3D G3DSA:3.10.50.10 318 376 6.5E-25 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 SUPERFAMILY SSF51445 44 314 1.55E-83 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 SUPERFAMILY SSF51445 374 410 1.55E-83 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 PANTHER PTHR11177 128 409 1.8E-91 T 16-09-2016 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 PANTHER PTHR11177 19 105 1.8E-91 T 16-09-2016 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 Pfam PF00704 Glycosyl hydrolases family 18 52 404 1.1E-76 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 Gene3D G3DSA:3.20.20.80 37 317 9.1E-87 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 Gene3D G3DSA:3.20.20.80 381 414 9.1E-87 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 ProSitePatterns PS01095 Chitinases family 18 active site. 185 193 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS05370 889e159d2a7f29e909ab9c3919be8460 415 SUPERFAMILY SSF54556 316 375 1.68E-14 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 Pfam PF00072 Response regulator receiver domain 20 125 8.3E-17 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 PANTHER PTHR26402:SF517 18 384 5.1E-76 T 16-09-2016 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 PANTHER PTHR26402 18 384 5.1E-76 T 16-09-2016 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 Gene3D G3DSA:3.40.50.2300 17 144 7.3E-26 T 16-09-2016 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 SUPERFAMILY SSF52172 17 162 1.14E-25 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 SMART SM00331 173 397 2.6E-15 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 SUPERFAMILY SSF81606 191 397 5.23E-5 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 397 3.2E-39 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31650 55b1c637cf5078bbbdef6bf15f3296e6 413 SMART SM00448 18 131 7.4E-16 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 Pfam PF00005 ABC transporter 30 171 1.5E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 PANTHER PTHR24220:SF593 14 231 3.2E-175 T 16-09-2016 Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 SUPERFAMILY SSF52540 12 233 5.93E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 PANTHER PTHR24220 14 231 3.2E-175 T 16-09-2016 Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 SMART SM00382 37 233 1.5E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14440 7aa8bcbf6cc776ee0b60c77c9045b70a 264 Gene3D G3DSA:3.40.50.300 9 232 3.6E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 303 541 9.9E-69 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 PANTHER PTHR30081:SF4 13 128 1.4E-264 T 16-09-2016 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 PANTHER PTHR30081:SF4 269 583 1.4E-264 T 16-09-2016 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 8 564 38.143 T 16-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 PANTHER PTHR30081 269 583 1.4E-264 T 16-09-2016 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 Pfam PF07549 SecD/SecF GG Motif 39 58 6.1E-4 T 16-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 Pfam PF02355 Protein export membrane protein 379 554 1.6E-11 T 16-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 Gene3D G3DSA:1.20.1640.10 388 557 1.2E-21 T 16-09-2016 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 44 549 3.6E-104 T 16-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 PANTHER PTHR30081 13 128 1.4E-264 T 16-09-2016 Spa2297_RS05740 afbe1c34a50c4d565a18c6a5a74f2890 596 SUPERFAMILY SSF82866 355 556 4.97E-32 T 16-09-2016 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PANTHER PTHR10992 3 276 2.1E-121 T 16-09-2016 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 Gene3D G3DSA:3.40.50.1820 3 275 2.0E-75 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 1.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 Pfam PF00561 alpha/beta hydrolase fold 24 259 7.1E-29 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 SUPERFAMILY SSF53474 1 275 2.57E-64 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PANTHER PTHR10992:SF859 3 276 2.1E-121 T 16-09-2016 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00412 Epoxide hydrolase signature 49 64 6.7E-6 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00412 Epoxide hydrolase signature 251 273 6.7E-6 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS31185 fc977c51b03d1bad189fee84135267f9 276 PRINTS PR00412 Epoxide hydrolase signature 29 47 6.7E-6 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS16460 5ca184e0d7f8a9f60f9954e1f86fa190 501 PIRSF PIRSF010361 20 470 4.3E-151 T 16-09-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane Spa2297_RS16460 5ca184e0d7f8a9f60f9954e1f86fa190 501 Pfam PF09594 Protein of unknown function (DUF2029) 125 357 1.4E-12 T 16-09-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 SUPERFAMILY SSF48179 165 251 1.25E-22 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 PANTHER PTHR21363 1 325 5.9E-63 T 16-09-2016 Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 Gene3D G3DSA:3.40.50.720 4 171 2.5E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 PANTHER PTHR21363:SF0 1 325 5.9E-63 T 16-09-2016 Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 SUPERFAMILY SSF51735 5 159 5.37E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 SUPERFAMILY SSF55021 294 354 1.71E-5 T 16-09-2016 Spa2297_RS06940 23e02feb7e137734b32a811d73a0dd67 361 Pfam PF02153 Prephenate dehydrogenase 17 250 1.2E-58 T 16-09-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 Gene3D G3DSA:1.20.1560.10 25 331 4.1E-59 T 16-09-2016 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 SUPERFAMILY SSF52540 352 590 2.21E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 PANTHER PTHR24221:SF138 30 589 2.9E-108 T 16-09-2016 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 Pfam PF00664 ABC transporter transmembrane region 36 307 2.4E-32 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 Gene3D G3DSA:3.40.50.300 355 585 5.8E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 SMART SM00382 381 567 6.2E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 PANTHER PTHR24221 30 589 2.9E-108 T 16-09-2016 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 SUPERFAMILY SSF90123 23 333 4.71E-56 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS31090 118e40bf53f102c74ad4b9c709c45bb0 595 Pfam PF00005 ABC transporter 372 521 7.5E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10015 c37e89eee6759c2c0504e5e0df150d45 156 Gene3D G3DSA:3.40.630.30 4 149 1.0E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS10015 c37e89eee6759c2c0504e5e0df150d45 156 PANTHER PTHR23091 4 154 2.8E-49 T 16-09-2016 Spa2297_RS10015 c37e89eee6759c2c0504e5e0df150d45 156 Pfam PF00583 Acetyltransferase (GNAT) family 71 145 2.4E-13 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS10015 c37e89eee6759c2c0504e5e0df150d45 156 SUPERFAMILY SSF55729 4 149 1.41E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS10015 c37e89eee6759c2c0504e5e0df150d45 156 PANTHER PTHR23091:SF246 4 154 2.8E-49 T 16-09-2016 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 181 1.3E-23 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 Gene3D G3DSA:1.10.10.10 121 181 9.6E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 SUPERFAMILY SSF88946 28 118 1.65E-13 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 Pfam PF08281 Sigma-70, region 4 127 179 1.6E-18 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 SUPERFAMILY SSF88659 119 181 1.44E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 Gene3D G3DSA:1.10.1740.10 27 99 5.8E-14 T 16-09-2016 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 28 184 1.2E-63 T 16-09-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 Pfam PF04542 Sigma-70 region 2 34 98 2.3E-8 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16105 ac270d64e10ae7951ff755a481d3b9ad 190 PANTHER PTHR30173 29 181 1.2E-28 T 16-09-2016 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 Gene3D G3DSA:3.30.450.20 162 290 5.3E-13 T 16-09-2016 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 Gene3D G3DSA:3.30.450.20 46 158 3.7E-18 T 16-09-2016 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 PANTHER PTHR24423 46 311 1.8E-21 T 16-09-2016 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 SUPERFAMILY SSF55785 161 289 5.83E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 Pfam PF08448 PAS fold 177 292 5.0E-8 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 SUPERFAMILY SSF55785 47 155 6.11E-20 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 Pfam PF00989 PAS fold 49 158 1.7E-12 T 16-09-2016 IPR013767 PAS fold GO:0006355 Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 SMART SM00091 47 115 2.6E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 SMART SM00091 171 236 0.8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 Gene3D G3DSA:3.30.450.40 309 479 5.7E-8 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS14465 f6f2f47c22c8329c9d5452a69b2ea108 486 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 168 4.2E-13 T 16-09-2016 IPR000014 PAS domain Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 235 9.8E-20 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 PANTHER PTHR10909 1 403 3.8E-203 T 16-09-2016 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Gene3D G3DSA:2.40.110.10 133 238 1.4E-39 T 16-09-2016 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 398 3.0E-33 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 SUPERFAMILY SSF56645 1 262 1.57E-61 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 2.6E-13 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 PANTHER PTHR10909:SF195 1 403 3.8E-203 T 16-09-2016 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 SUPERFAMILY SSF47203 248 403 2.9E-40 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Gene3D G3DSA:1.20.140.10 239 402 2.8E-44 T 16-09-2016 Spa2297_RS06605 8dc6958869127724aa354c61f5d85ec2 404 Gene3D G3DSA:1.10.540.10 1 132 2.4E-32 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 SMART SM01091 354 438 2.5E-15 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 PANTHER PTHR22777 1 446 1.6E-150 T 16-09-2016 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Gene3D G3DSA:3.10.580.10 208 349 2.6E-15 T 16-09-2016 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Pfam PF01595 Domain of unknown function DUF21 12 202 1.8E-34 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Pfam PF03471 Transporter associated domain 357 437 7.9E-19 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 PANTHER PTHR22777:SF18 1 446 1.6E-150 T 16-09-2016 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Pfam PF00571 CBS domain 228 274 8.2E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Pfam PF00571 CBS domain 293 340 3.7E-5 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 SUPERFAMILY SSF54631 208 343 6.57E-26 T 16-09-2016 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 Gene3D G3DSA:3.30.465.10 357 445 2.1E-20 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS17290 6419d2aed7219d228b74bdcea7afe744 447 SUPERFAMILY SSF56176 356 444 2.56E-17 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 SMART SM00849 18 199 0.0027 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 PANTHER PTHR12553 1 250 1.5E-54 T 16-09-2016 Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 Pfam PF12706 Beta-lactamase superfamily domain 30 218 2.2E-21 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 Gene3D G3DSA:3.60.15.10 1 249 1.4E-58 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 PANTHER PTHR12553:SF51 1 250 1.5E-54 T 16-09-2016 Spa2297_RS12440 2908ff2f06983ae996c41e98c95a1834 250 SUPERFAMILY SSF56281 1 249 8.52E-54 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 Gene3D G3DSA:3.40.50.300 12 225 5.3E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 Hamap MF_00238 Cytidylate kinase [cmk]. 12 228 30.453 T 16-09-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 TIGRFAM TIGR00017 cmk: cytidylate kinase 12 222 2.2E-60 T 16-09-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 PANTHER PTHR21299 13 230 9.7E-60 T 16-09-2016 Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 Pfam PF02224 Cytidylate kinase 14 225 6.5E-63 T 16-09-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 Spa2297_RS06935 95153b87be67cd6d87a73e1bc320cbc8 231 SUPERFAMILY SSF52540 12 227 1.07E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 Pfam PF00005 ABC transporter 18 160 6.2E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 SUPERFAMILY SSF50331 237 338 3.51E-7 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 Gene3D G3DSA:3.40.50.300 2 233 2.9E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 PANTHER PTHR24220 4 277 1.4E-111 T 16-09-2016 Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 SMART SM00382 27 210 1.0E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 Pfam PF08402 TOBE domain 268 338 1.6E-9 T 16-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 SUPERFAMILY SSF52540 2 240 2.95E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 PANTHER PTHR24220:SF123 4 277 1.4E-111 T 16-09-2016 Spa2297_RS23860 1fad02f4032b2c6c91df7c3241347cfe 339 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 TIGRFAM TIGR01499 folC: bifunctional protein FolC 86 498 4.0E-97 T 16-09-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 Gene3D G3DSA:3.90.190.20 364 503 3.3E-38 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 Pfam PF08245 Mur ligase middle domain 107 334 2.1E-14 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 Gene3D G3DSA:3.40.1190.10 81 361 7.7E-94 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 PANTHER PTHR11136:SF0 81 503 1.3E-130 T 16-09-2016 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 PANTHER PTHR11136 81 503 1.3E-130 T 16-09-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 SUPERFAMILY SSF53244 364 502 1.54E-27 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 Pfam PF02875 Mur ligase family, glutamate ligase domain 363 441 1.9E-11 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 SUPERFAMILY SSF53623 65 359 7.23E-88 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS11050 ab2544df732716f491a3f413466b24a0 504 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 203 218 - T 16-09-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 SUPERFAMILY SSF46689 257 302 8.51E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 Gene3D G3DSA:2.60.120.280 50 158 4.2E-8 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 SUPERFAMILY SSF51215 18 179 8.76E-15 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 Pfam PF02311 AraC-like ligand binding domain 40 153 4.1E-14 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 Pfam PF12833 Helix-turn-helix domain 223 301 2.3E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 Gene3D G3DSA:1.10.10.60 208 251 6.8E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 PANTHER PTHR11019 11 304 1.2E-154 T 16-09-2016 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 SMART SM00342 217 300 3.8E-26 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 Gene3D G3DSA:1.10.10.60 257 302 4.1E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27715 692f3eb7e21967211498769a7342c563 304 PANTHER PTHR11019:SF137 11 304 1.2E-154 T 16-09-2016 Spa2297_RS08255 782a7e8f314d8324b701d41e3c17681a 328 SUPERFAMILY SSF101478 19 305 7.98E-51 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS08255 782a7e8f314d8324b701d41e3c17681a 328 PANTHER PTHR16222:SF12 15 305 3.2E-77 T 16-09-2016 Spa2297_RS08255 782a7e8f314d8324b701d41e3c17681a 328 PANTHER PTHR16222 15 305 3.2E-77 T 16-09-2016 Spa2297_RS08255 782a7e8f314d8324b701d41e3c17681a 328 Pfam PF03747 ADP-ribosylglycohydrolase 25 299 6.4E-53 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 PIRSF PIRSF003085 13 431 2.0E-111 T 16-09-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 174 389 2.2E-4 T 16-09-2016 IPR020803 Polyketide synthase, methyltransferase domain Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 PANTHER PTHR10108:SF743 72 329 4.0E-87 T 16-09-2016 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 PANTHER PTHR10108:SF743 346 427 4.0E-87 T 16-09-2016 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 PANTHER PTHR10108 346 427 4.0E-87 T 16-09-2016 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 PANTHER PTHR10108 72 329 4.0E-87 T 16-09-2016 Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 Gene3D G3DSA:3.40.50.150 139 411 1.5E-85 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 SUPERFAMILY SSF53335 149 414 3.35E-72 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30515 9735bf5ee56e1b9f9b4898cf560072e0 436 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 409 2.1E-76 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 Gene3D G3DSA:3.50.50.60 388 438 1.4E-7 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 Gene3D G3DSA:3.50.50.60 245 280 1.4E-7 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PANTHER PTHR23023 61 338 1.5E-221 T 16-09-2016 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 65 87 2.6E-5 T 16-09-2016 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 267 2.6E-5 T 16-09-2016 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PANTHER PTHR23023:SF29 61 338 1.5E-221 T 16-09-2016 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PANTHER PTHR23023:SF29 356 595 1.5E-221 T 16-09-2016 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 Gene3D G3DSA:3.50.50.60 61 244 3.9E-57 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 Gene3D G3DSA:3.50.50.60 483 589 3.9E-57 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 65 275 9.9E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 SUPERFAMILY SSF51905 392 518 1.94E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 SUPERFAMILY SSF51905 65 301 1.94E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29240 66fa185d2a2ac4d7a6973a1b41e6e4e5 600 PANTHER PTHR23023 356 595 1.5E-221 T 16-09-2016 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 PANTHER PTHR24362:SF160 1 259 1.1E-69 T 16-09-2016 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 Gene3D G3DSA:1.10.510.10 76 247 5.1E-32 T 16-09-2016 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 PANTHER PTHR24362 1 259 1.1E-69 T 16-09-2016 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 SUPERFAMILY SSF56112 6 258 5.93E-58 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 Pfam PF00069 Protein kinase domain 10 212 6.5E-35 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 SMART SM00220 10 259 6.9E-45 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 Gene3D G3DSA:3.30.200.20 6 75 7.3E-24 T 16-09-2016 Spa2297_RS31405 34b4846de40478ecce687cabf13443ad 460 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 SMART SM00642 154 450 0.0041 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 PANTHER PTHR10357 1 87 3.0E-225 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 PANTHER PTHR10357 121 453 3.0E-225 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 Gene3D G3DSA:3.20.20.80 155 453 2.0E-57 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 PANTHER PTHR10357:SF137 121 453 3.0E-225 T 16-09-2016 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 PANTHER PTHR10357:SF137 1 87 3.0E-225 T 16-09-2016 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 Pfam PF11896 Domain of unknown function (DUF3416) 1 148 1.4E-37 T 16-09-2016 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 Spa2297_RS33535 d28b8ee89a401902ef657fc01f2cb9f7 453 SUPERFAMILY SSF51445 155 453 4.58E-69 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PANTHER PTHR22893 3 418 9.6E-250 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 376 633 4.2E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 SUPERFAMILY SSF51905 461 519 2.69E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 SUPERFAMILY SSF51905 555 649 2.69E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 SUPERFAMILY SSF51395 3 363 4.23E-116 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 331 3.1E-87 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 SUPERFAMILY SSF51971 334 520 7.06E-43 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 498 516 1.5E-11 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 617 633 1.5E-11 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 397 1.5E-11 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PANTHER PTHR22893:SF25 3 418 9.6E-250 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 Gene3D G3DSA:3.50.50.60 361 465 1.0E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 Gene3D G3DSA:3.50.50.60 470 624 4.0E-47 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 399 1.0E-5 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 618 632 1.0E-5 T 16-09-2016 Spa2297_RS03045 83d0ef6b79a83522a2132a59bd055f0f 671 Gene3D G3DSA:3.20.20.70 4 360 1.1E-126 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 SUPERFAMILY SSF51206 88 219 4.32E-19 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 SMART SM00100 96 219 5.5E-7 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 PANTHER PTHR24567:SF37 285 479 1.1E-144 T 16-09-2016 Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 PANTHER PTHR24567:SF37 15 217 1.1E-144 T 16-09-2016 Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 PANTHER PTHR24567 285 479 1.1E-144 T 16-09-2016 Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 PANTHER PTHR24567 15 217 1.1E-144 T 16-09-2016 Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 Pfam PF00027 Cyclic nucleotide-binding domain 116 201 9.0E-13 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS00455 0348ef1e0ad7e051fbb15eb9815a8134 479 Gene3D G3DSA:2.60.120.10 89 222 4.6E-18 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS21805 ead7425cfdf0559302520507ef2c71c4 257 SUPERFAMILY SSF47240 47 168 2.72E-9 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS21805 ead7425cfdf0559302520507ef2c71c4 257 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 41 225 2.0E-99 T 16-09-2016 Spa2297_RS21805 ead7425cfdf0559302520507ef2c71c4 257 Gene3D G3DSA:1.20.1260.10 45 169 1.5E-8 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 16-09-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 Pfam PF01192 RNA polymerase Rpb6 18 80 9.7E-15 T 16-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 Gene3D G3DSA:3.90.940.10 11 85 5.3E-34 T 16-09-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 PANTHER PTHR34476 12 86 1.9E-24 T 16-09-2016 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.5E-22 T 16-09-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 SMART SM01409 18 82 2.2E-14 T 16-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS05560 ee8a610e3e1d3020120affccf75a1063 90 SUPERFAMILY SSF63562 11 86 1.06E-24 T 16-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 SUPERFAMILY SSF53720 7 530 2.09E-123 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 PANTHER PTHR11699 22 545 1.7E-260 T 16-09-2016 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 PANTHER PTHR11699:SF18 22 545 1.7E-260 T 16-09-2016 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 545 2.0E-238 T 16-09-2016 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|UniPathway: UPA00261 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 Gene3D G3DSA:3.40.309.10 303 504 2.6E-43 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 Gene3D G3DSA:3.40.605.10 41 302 4.7E-64 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23370 4e8a9f0e821ed211ed3c957dd44379da 546 Pfam PF00171 Aldehyde dehydrogenase family 55 529 5.2E-103 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 SUPERFAMILY SSF53383 7 406 1.11E-76 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 Gene3D G3DSA:3.40.640.10 82 261 2.3E-22 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 Pfam PF00266 Aminotransferase class-V 99 320 1.1E-17 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 Hamap MF_01970 Kynureninase [kynU]. 1 404 32.205 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 Gene3D G3DSA:3.90.1150.10 262 407 1.5E-40 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 PANTHER PTHR14084 7 414 3.3E-102 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS02660 b50a8cc17575465cf4f18b25825b8a64 420 PIRSF PIRSF038800 2 411 9.0E-125 T 16-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SMART SM00382 40 232 0.0082 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031 920 946 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 Pfam PF08494 DEAD/H associated 669 878 4.1E-77 T 16-09-2016 IPR013701 DEAD/H associated GO:0005524|GO:0016818 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031:SF122 920 946 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031:SF122 24 234 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031:SF122 340 422 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SUPERFAMILY SSF52540 336 414 5.09E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SUPERFAMILY SSF52540 36 213 5.09E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SUPERFAMILY SSF52540 262 305 5.09E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 Pfam PF00270 DEAD/DEAH box helicase 28 211 2.1E-27 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SMART SM00490 293 405 1.9E-13 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 Gene3D G3DSA:3.40.50.300 17 219 1.2E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 Gene3D G3DSA:3.40.50.300 272 423 2.6E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031 24 234 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031 340 422 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 SMART SM00487 23 242 2.1E-37 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031 274 306 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031 649 678 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031:SF122 649 678 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 PANTHER PTHR24031:SF122 274 306 8.9E-69 T 16-09-2016 Spa2297_RS24365 b352e7130caf989ee6f8788f4cdaf6d7 1697 Pfam PF00271 Helicase conserved C-terminal domain 279 405 1.2E-11 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 Hamap MF_01962 Adenine deaminase. 1 311 81.946 T 16-09-2016 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 SUPERFAMILY SSF51556 4 314 7.12E-81 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 PANTHER PTHR11409 1 327 3.1E-170 T 16-09-2016 Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 Pfam PF00962 Adenosine/AMP deaminase 3 315 2.1E-70 T 16-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 Gene3D G3DSA:3.20.20.140 3 319 2.4E-97 T 16-09-2016 Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 PANTHER PTHR11409:SF41 1 327 3.1E-170 T 16-09-2016 Spa2297_RS10720 2dc563674695bd55170663afbde50564 332 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 3 321 1.1E-110 T 16-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 PANTHER PTHR10438 19 149 6.4E-50 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 PANTHER PTHR10438 206 227 6.4E-50 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Gene3D G3DSA:1.25.40.10 181 227 1.5E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Pfam PF14559 Tetratricopeptide repeat 192 228 2.5E-6 T 16-09-2016 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Pfam PF00085 Thioredoxin 43 145 3.3E-23 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Gene3D G3DSA:3.40.30.10 40 147 2.7E-28 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Gene3D G3DSA:1.25.40.10 235 318 2.9E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 SUPERFAMILY SSF52833 40 147 1.44E-30 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 Pfam PF14561 Tetratricopeptide repeat 229 318 1.0E-23 T 16-09-2016 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 PANTHER PTHR10438:SF282 19 149 6.4E-50 T 16-09-2016 Spa2297_RS22905 87bbda9ed6b291ce8a4fa75665d3d252 318 PANTHER PTHR10438:SF282 206 227 6.4E-50 T 16-09-2016 Spa2297_RS34370 5650d71f071def3c2aef50595bec00fd 511 SUPERFAMILY SSF53474 344 509 9.56E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS34370 5650d71f071def3c2aef50595bec00fd 511 Gene3D G3DSA:3.40.50.1820 345 508 2.0E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS34370 5650d71f071def3c2aef50595bec00fd 511 Pfam PF01738 Dienelactone hydrolase family 344 508 4.4E-9 T 16-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 SUPERFAMILY SSF143744 19 159 1.96E-28 T 16-09-2016 Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 Pfam PF03928 Haem-degrading 28 156 5.7E-34 T 16-09-2016 IPR005624 Haem-degrading Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 PANTHER PTHR28255 13 161 4.5E-52 T 16-09-2016 Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 Hamap MF_00761 UPF0303 protein . 7 161 34.58 T 16-09-2016 IPR010371 Uncharacterised protein family UPF0303 Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 PANTHER PTHR28255:SF1 13 161 4.5E-52 T 16-09-2016 Spa2297_RS12210 1768e4884208bd71fe57e28842377fe0 161 PIRSF PIRSF008757 4 161 2.5E-64 T 16-09-2016 IPR010371 Uncharacterised protein family UPF0303 Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 SUPERFAMILY SSF46894 2 66 1.36E-7 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 Pfam PF00486 Transcriptional regulatory protein, C terminal 2 66 6.3E-6 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 SUPERFAMILY SSF48452 68 235 1.65E-32 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 SMART SM01043 73 218 5.6E-36 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 Gene3D G3DSA:1.10.10.10 2 69 2.7E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 SUPERFAMILY SSF55073 281 419 2.83E-6 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 Pfam PF03704 Bacterial transcriptional activator domain 73 217 1.6E-38 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS02985 dfd3fc162da546ab8e6cbd61fd6ed452 450 PANTHER PTHR35807 3 307 2.6E-48 T 16-09-2016 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.9E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 Gene3D G3DSA:1.10.10.60 3 59 4.9E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 SUPERFAMILY SSF48498 92 170 1.56E-5 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 PANTHER PTHR30055:SF33 1 194 1.5E-53 T 16-09-2016 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 PANTHER PTHR30055 1 194 1.5E-53 T 16-09-2016 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 Gene3D G3DSA:1.10.357.10 60 195 9.8E-22 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS11750 1fbd5333aacf3d98a396f13a70426c7c 203 SUPERFAMILY SSF46689 3 70 4.99E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25215 0184b4cc38d49764a97c17f6360b3f5e 172 Pfam PF01464 Transglycosylase SLT domain 97 167 1.6E-8 T 16-09-2016 IPR008258 Transglycosylase SLT domain 1 Spa2297_RS25215 0184b4cc38d49764a97c17f6360b3f5e 172 Gene3D G3DSA:1.10.530.10 93 168 2.5E-8 T 16-09-2016 Spa2297_RS25215 0184b4cc38d49764a97c17f6360b3f5e 172 SUPERFAMILY SSF53955 73 167 7.73E-13 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 1.5E-22 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.5E-22 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 1.5E-22 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.5E-22 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PRINTS PR00151 Porphobilinogen deaminase signature 126 143 1.5E-22 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 300 33.848 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 2.3E-61 T 16-09-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PANTHER PTHR11557 5 309 1.5E-121 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 298 3.9E-13 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 300 2.8E-98 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 SUPERFAMILY SSF54782 223 309 2.22E-20 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 PIRSF PIRSF001438 2 311 2.3E-97 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Gene3D G3DSA:3.40.190.10 113 201 6.4E-32 T 16-09-2016 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Gene3D G3DSA:3.40.190.10 7 112 6.1E-35 T 16-09-2016 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 16-09-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 SUPERFAMILY SSF53850 6 218 3.11E-65 T 16-09-2016 Spa2297_RS01960 2d5cd6ac940c21506d700ef49220d611 311 Gene3D G3DSA:3.30.160.40 223 307 1.3E-19 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 Gene3D G3DSA:3.30.565.10 310 395 6.6E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 SUPERFAMILY SSF55874 298 395 1.25E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 Pfam PF07730 Histidine kinase 194 259 5.5E-18 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 PANTHER PTHR24421:SF26 45 395 3.2E-80 T 16-09-2016 Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 SMART SM00387 303 397 8.9E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24090 5351975aac26fd727575ef067bb52b33 398 PANTHER PTHR24421 45 395 3.2E-80 T 16-09-2016 Spa2297_RS26840 37b6b3da0addb6782d2541fe8d44844e 169 SMART SM00506 3 137 1.0E-52 T 16-09-2016 IPR002589 Macro domain Spa2297_RS26840 37b6b3da0addb6782d2541fe8d44844e 169 Pfam PF01661 Macro domain 20 137 1.2E-39 T 16-09-2016 IPR002589 Macro domain Spa2297_RS26840 37b6b3da0addb6782d2541fe8d44844e 169 Gene3D G3DSA:3.40.220.10 3 165 3.9E-60 T 16-09-2016 Spa2297_RS26840 37b6b3da0addb6782d2541fe8d44844e 169 PANTHER PTHR11106 3 167 1.7E-72 T 16-09-2016 Spa2297_RS26840 37b6b3da0addb6782d2541fe8d44844e 169 SUPERFAMILY SSF52949 3 165 9.08E-58 T 16-09-2016 Spa2297_RS25565 7a3af288d40e44ac682abb94a68146f1 221 PANTHER PTHR30177 6 220 7.7E-65 T 16-09-2016 Spa2297_RS25565 7a3af288d40e44ac682abb94a68146f1 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 219 3.7E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25565 7a3af288d40e44ac682abb94a68146f1 221 Gene3D G3DSA:1.10.3720.10 22 203 8.2E-26 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25565 7a3af288d40e44ac682abb94a68146f1 221 SUPERFAMILY SSF161098 22 205 1.57E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 SUPERFAMILY SSF46689 16 85 2.51E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 PANTHER PTHR30055 9 174 5.4E-19 T 16-09-2016 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 68 1.6E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 PANTHER PTHR30055:SF80 9 174 5.4E-19 T 16-09-2016 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 Gene3D G3DSA:1.10.10.60 15 68 3.7E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.6E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.6E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21460 f9cb06d9c7d640b9cd9ce5f2236d7c17 219 Gene3D G3DSA:1.10.357.10 69 207 7.7E-13 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 SUPERFAMILY SSF46785 4 98 9.35E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 Gene3D G3DSA:1.20.120.530 75 210 1.3E-27 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 7.0E-19 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 PANTHER PTHR11751 8 98 1.3E-49 T 16-09-2016 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 PANTHER PTHR11751:SF403 8 98 1.3E-49 T 16-09-2016 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 Pfam PF07729 FCD domain 82 203 8.4E-25 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 Gene3D G3DSA:1.10.10.10 4 73 2.8E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 SMART SM00345 14 72 1.0E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 SUPERFAMILY SSF48008 78 209 7.32E-25 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.2E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.2E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS27335 eff792dce1c6f47fde2647d5d3fb129b 215 SMART SM00895 82 204 6.1E-19 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 SMART SM00382 367 535 1.8E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 SMART SM00382 30 222 1.0E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 SUPERFAMILY SSF52540 17 220 7.41E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 PANTHER PTHR19211 292 538 4.5E-211 T 16-09-2016 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 PANTHER PTHR19211 1 252 4.5E-211 T 16-09-2016 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 Pfam PF00005 ABC transporter 360 489 6.0E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 Pfam PF00005 ABC transporter 23 171 4.5E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 SUPERFAMILY SSF52540 350 540 4.0E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 PANTHER PTHR19211:SF6 292 538 4.5E-211 T 16-09-2016 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 PANTHER PTHR19211:SF6 1 252 4.5E-211 T 16-09-2016 Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 Gene3D G3DSA:3.40.50.300 354 541 3.1E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00100 e099ac7788455a80108a557d79f55b3d 544 Gene3D G3DSA:3.40.50.300 8 261 3.0E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 SUPERFAMILY SSF51735 98 278 9.97E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 Gene3D G3DSA:3.40.50.720 114 279 2.6E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 Gene3D G3DSA:3.40.50.720 34 113 1.4E-15 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 PANTHER PTHR10996:SF160 1 309 1.1E-168 T 16-09-2016 Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 PANTHER PTHR10996 1 309 1.1E-168 T 16-09-2016 Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 16-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spa2297_RS23320 51f34f363aeee96f90fa73b988854334 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 277 7.1E-45 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 Pfam PF01841 Transglutaminase-like superfamily 433 548 9.9E-26 T 16-09-2016 IPR002931 Transglutaminase-like Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 SMART SM00460 480 550 1.1E-25 T 16-09-2016 IPR002931 Transglutaminase-like Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 PANTHER PTHR33490 27 796 5.2E-184 T 16-09-2016 Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 PANTHER PTHR33490:SF4 27 796 5.2E-184 T 16-09-2016 Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 Gene3D G3DSA:3.90.260.10 414 570 2.5E-23 T 16-09-2016 IPR002931 Transglutaminase-like Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 Pfam PF13559 Domain of unknown function (DUF4129) 670 735 4.4E-9 T 16-09-2016 IPR025403 Domain of unknown function DUF4129 Spa2297_RS08585 5277bf1651f67476d6fcef2ab84297a7 796 SUPERFAMILY SSF54001 413 568 1.54E-34 T 16-09-2016 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 Pfam PF04055 Radical SAM superfamily 274 439 5.2E-15 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 PANTHER PTHR11918:SF77 45 202 1.1E-255 T 16-09-2016 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 PANTHER PTHR11918:SF77 236 624 1.1E-255 T 16-09-2016 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 18 623 1.1E-212 T 16-09-2016 IPR023862 Conserved hypothetical protein CHP03960, radical SAM Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 PANTHER PTHR11918 45 202 1.1E-255 T 16-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 PANTHER PTHR11918 236 624 1.1E-255 T 16-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 SUPERFAMILY SSF102114 238 640 6.15E-51 T 16-09-2016 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 SMART SM00729 270 493 7.4E-28 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS11010 149ef0abe0d518d825396904dd248b02 649 Gene3D G3DSA:3.80.30.20 269 498 5.4E-45 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PANTHER PTHR23115 4 336 5.4E-67 T 16-09-2016 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PANTHER PTHR23115:SF91 4 336 5.4E-67 T 16-09-2016 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 Gene3D G3DSA:2.40.30.10 238 361 9.0E-19 T 16-09-2016 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 SUPERFAMILY SSF50465 329 429 1.49E-24 T 16-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 75 90 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 SUPERFAMILY SSF52540 19 224 3.14E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PRINTS PR00315 GTP-binding elongation factor signature 23 36 1.5E-11 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PRINTS PR00315 GTP-binding elongation factor signature 82 90 1.5E-11 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.5E-11 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PRINTS PR00315 GTP-binding elongation factor signature 118 129 1.5E-11 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 PRINTS PR00315 GTP-binding elongation factor signature 102 112 1.5E-11 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 SUPERFAMILY SSF50447 235 325 4.71E-18 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 22 429 1.6E-162 T 16-09-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 Gene3D G3DSA:3.40.50.300 7 226 1.4E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25760 6a0dc2361525731b5b1f0de0aac0c3c0 451 Pfam PF00009 Elongation factor Tu GTP binding domain 22 205 2.6E-39 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 SUPERFAMILY SSF53067 83 398 2.46E-47 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 PANTHER PTHR18964 61 275 4.9E-102 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 PANTHER PTHR18964:SF108 61 275 4.9E-102 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 Pfam PF00480 ROK family 86 395 2.1E-36 T 16-09-2016 IPR000600 ROK family Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 Gene3D G3DSA:3.30.420.40 81 225 8.7E-35 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 Gene3D G3DSA:1.10.10.10 11 79 1.7E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 PANTHER PTHR18964 310 397 4.9E-102 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 PANTHER PTHR18964:SF108 310 397 4.9E-102 T 16-09-2016 Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 SUPERFAMILY SSF46785 12 75 1.11E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29740 24b2f388ecfb7a4bfb370bfce770216f 429 Gene3D G3DSA:3.30.420.40 226 380 1.3E-39 T 16-09-2016 Spa2297_RS29975 95b52520090bcaba6c1b12a2ce471bb3 166 PANTHER PTHR11124 1 164 1.6E-33 T 16-09-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 Spa2297_RS29975 95b52520090bcaba6c1b12a2ce471bb3 166 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 148 2.0E-26 T 16-09-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 Spa2297_RS29975 95b52520090bcaba6c1b12a2ce471bb3 166 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 149 1.8E-23 T 16-09-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Spa2297_RS29975 95b52520090bcaba6c1b12a2ce471bb3 166 Gene3D G3DSA:3.60.21.10 2 157 4.3E-30 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS29975 95b52520090bcaba6c1b12a2ce471bb3 166 SUPERFAMILY SSF56300 2 163 2.58E-34 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 Pfam PF00210 Ferritin-like domain 50 192 1.1E-30 T 16-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 93 109 2.2E-6 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 69 85 2.2E-6 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 ProSitePatterns PS00819 Dps protein family signature 2. 95 109 - T 16-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 Gene3D G3DSA:1.20.1260.10 21 194 4.8E-49 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 PANTHER PTHR30295 49 195 1.0E-80 T 16-09-2016 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 ProSitePatterns PS00818 Dps protein family signature 1. 69 85 - T 16-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 PIRSF PIRSF005900 26 194 3.9E-45 T 16-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 PANTHER PTHR30295:SF4 49 195 1.0E-80 T 16-09-2016 Spa2297_RS03515 7e92ad18113fa51fdd9cf7aceebb7303 196 SUPERFAMILY SSF47240 28 188 1.67E-38 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 Gene3D G3DSA:1.10.10.10 4 74 2.2E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 SUPERFAMILY SSF46785 5 77 6.12E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 Gene3D G3DSA:3.30.450.40 75 250 3.0E-43 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 SUPERFAMILY SSF55781 71 250 2.88E-37 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 5.4E-34 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 Pfam PF09339 IclR helix-turn-helix domain 7 58 3.2E-17 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 PANTHER PTHR30136:SF13 3 250 1.0E-103 T 16-09-2016 Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 SMART SM00346 5 95 2.3E-35 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS06440 bbc8824047fc42a29de7f4f3c05d0992 254 PANTHER PTHR30136 3 250 1.0E-103 T 16-09-2016 Spa2297_RS02560 ced0220cee3663c9a82c32011e4980c6 192 SUPERFAMILY SSF53597 5 183 2.45E-21 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS02560 ced0220cee3663c9a82c32011e4980c6 192 Gene3D G3DSA:3.40.430.10 4 181 3.6E-17 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS02560 ced0220cee3663c9a82c32011e4980c6 192 PANTHER PTHR38011 2 184 3.6E-52 T 16-09-2016 Spa2297_RS02560 ced0220cee3663c9a82c32011e4980c6 192 PANTHER PTHR38011:SF2 2 184 3.6E-52 T 16-09-2016 Spa2297_RS02560 ced0220cee3663c9a82c32011e4980c6 192 Pfam PF01872 RibD C-terminal domain 4 176 1.3E-25 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS20990 367c593f2cbc8d8b60280d439f3e6936 285 Pfam PF01061 ABC-2 type transporter 26 240 2.4E-27 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS20990 367c593f2cbc8d8b60280d439f3e6936 285 PANTHER PTHR30294 19 281 1.8E-115 T 16-09-2016 Spa2297_RS20990 367c593f2cbc8d8b60280d439f3e6936 285 PIRSF PIRSF006648 2 285 6.9E-72 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS20990 367c593f2cbc8d8b60280d439f3e6936 285 PANTHER PTHR30294:SF24 19 281 1.8E-115 T 16-09-2016 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 SUPERFAMILY SSF52743 152 443 1.96E-37 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PANTHER PTHR10795 201 375 1.7E-13 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 Pfam PF00082 Subtilase family 194 443 1.6E-14 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 Gene3D G3DSA:3.40.50.200 158 356 9.7E-33 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 Gene3D G3DSA:3.40.50.200 406 445 9.7E-33 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 16-09-2016 IPR022398 Peptidase S8, subtilisin, His-active site Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PANTHER PTHR10795:SF419 201 375 1.7E-13 T 16-09-2016 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PANTHER PTHR10795:SF419 409 444 1.7E-13 T 16-09-2016 Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 1.1E-8 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 1.1E-8 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 177 1.1E-8 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 PANTHER PTHR10795 409 444 1.7E-13 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS28590 fd4df1b0f291f9232b6f4aae6baa4ca3 477 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 SUPERFAMILY SSF53335 35 218 4.82E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 Gene3D G3DSA:3.40.50.150 191 211 9.9E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 Gene3D G3DSA:3.40.50.150 33 156 9.9E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 PANTHER PTHR10108 193 207 6.1E-12 T 16-09-2016 Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 PANTHER PTHR10108 33 174 6.1E-12 T 16-09-2016 Spa2297_RS08080 fb747574e11807614f016ae0fb394cab 228 Pfam PF08241 Methyltransferase domain 46 134 7.9E-11 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 SUPERFAMILY SSF52317 1 213 7.41E-43 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 Hamap MF_00510 Peptidase E [pepE]. 1 213 46.955 T 16-09-2016 IPR023172 Peptidase S51, dipeptidase E GO:0016805 Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 Gene3D G3DSA:3.40.50.880 1 226 4.7E-76 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 PANTHER PTHR20842 2 232 3.9E-105 T 16-09-2016 Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 Pfam PF03575 Peptidase family S51 3 202 7.5E-61 T 16-09-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 Spa2297_RS30730 714e8e720d89f2f52fea33462c9bf6e0 241 PANTHER PTHR20842:SF2 2 232 3.9E-105 T 16-09-2016 Spa2297_RS04840 056aab59cddbb944b4dc8d3b114172cf 145 Pfam PF14539 Domain of unknown function (DUF4442) 6 140 6.4E-24 T 16-09-2016 IPR027961 Protein of unknown function DUF4442 Spa2297_RS04840 056aab59cddbb944b4dc8d3b114172cf 145 SUPERFAMILY SSF54637 6 143 1.1E-15 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS04840 056aab59cddbb944b4dc8d3b114172cf 145 Gene3D G3DSA:3.10.129.10 6 144 4.3E-35 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PANTHER PTHR23501 6 496 5.3E-181 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PANTHER PTHR23501:SF48 6 496 5.3E-181 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 Gene3D G3DSA:1.20.1250.20 17 208 4.5E-31 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 SUPERFAMILY SSF103473 464 492 5.49E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 SUPERFAMILY SSF103473 257 429 5.49E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 SUPERFAMILY SSF103473 6 209 5.49E-60 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 5.8E-10 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 5.8E-10 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 5.8E-10 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 410 429 5.8E-10 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 Gene3D G3DSA:1.20.1250.20 267 430 3.2E-13 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 Gene3D G3DSA:1.20.1250.20 465 492 3.2E-13 T 16-09-2016 Spa2297_RS16035 21da4d579fa7f5bfd3faa5ef5d731bf4 496 Pfam PF07690 Major Facilitator Superfamily 28 419 3.8E-48 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 Gene3D G3DSA:3.40.190.10 114 197 4.1E-17 T 16-09-2016 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 PANTHER PTHR30126 23 292 8.1E-86 T 16-09-2016 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 SUPERFAMILY SSF46785 22 132 7.44E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 Gene3D G3DSA:1.10.10.10 24 108 8.5E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 83 5.0E-20 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 Pfam PF03466 LysR substrate binding domain 111 308 9.3E-43 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 SUPERFAMILY SSF53850 113 308 8.69E-38 T 16-09-2016 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 PANTHER PTHR30126:SF11 23 292 8.1E-86 T 16-09-2016 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 Gene3D G3DSA:3.40.190.10 198 281 4.6E-18 T 16-09-2016 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 2.4E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 2.4E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS06235 2fc431682f14bb8618daa6959973e068 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.4E-6 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 Gene3D G3DSA:1.20.1250.20 22 207 2.7E-30 T 16-09-2016 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 429 1.0E-71 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 Pfam PF07690 Major Facilitator Superfamily 29 420 8.4E-58 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 SUPERFAMILY SSF103473 258 430 1.7E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 SUPERFAMILY SSF103473 8 208 1.7E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 SUPERFAMILY SSF103473 472 496 1.7E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 PANTHER PTHR23501:SF69 21 514 2.7E-171 T 16-09-2016 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 PANTHER PTHR23501 21 514 2.7E-171 T 16-09-2016 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 Gene3D G3DSA:1.20.1250.20 473 497 1.2E-19 T 16-09-2016 Spa2297_RS00380 021548484402cf7654bdbbc1f82c6fb3 515 Gene3D G3DSA:1.20.1250.20 273 430 1.2E-19 T 16-09-2016 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 16-09-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 SMART SM00922 125 230 1.6E-20 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 SUPERFAMILY SSF51604 95 358 7.21E-71 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 Gene3D G3DSA:3.20.20.120 114 348 2.6E-76 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 PANTHER PTHR13794 1 381 2.7E-127 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 SUPERFAMILY SSF54826 1 112 1.84E-30 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 Pfam PF13378 Enolase C-terminal domain-like 128 354 2.8E-58 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 PANTHER PTHR13794:SF4 1 381 2.7E-127 T 16-09-2016 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 Gene3D G3DSA:3.30.390.10 2 113 8.3E-43 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS29435 d392af3cc0f7676bb18f26be7d669fe1 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.1E-22 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 106 - T 16-09-2016 IPR023765 Solute-binding protein family 5, conserved site Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 SUPERFAMILY SSF53850 34 521 3.8E-115 T 16-09-2016 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 PANTHER PTHR30290 1 530 2.0E-233 T 16-09-2016 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 PIRSF PIRSF002741 1 523 5.5E-101 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 435 2.6E-84 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 Gene3D G3DSA:3.90.76.10 47 191 1.2E-37 T 16-09-2016 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 Gene3D G3DSA:3.10.105.10 293 490 2.9E-36 T 16-09-2016 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 Gene3D G3DSA:3.40.190.10 192 292 7.8E-30 T 16-09-2016 Spa2297_RS26850 ca41c3e9b4675b83f9f5bce161ca2294 530 PANTHER PTHR30290:SF27 1 530 2.0E-233 T 16-09-2016 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 Gene3D G3DSA:3.20.20.80 17 474 1.3E-161 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 387 6.5E-22 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 445 457 6.5E-22 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 411 6.5E-22 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 438 6.5E-22 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 300 314 6.5E-22 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 SUPERFAMILY SSF51445 17 474 2.56E-163 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 379 387 - T 16-09-2016 IPR018120 Glycoside hydrolase family 1, active site Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 Pfam PF00232 Glycosyl hydrolase family 1 16 473 3.9E-160 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PANTHER PTHR10353 16 477 1.3E-199 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 22 36 - T 16-09-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 TIGRFAM TIGR03356 BGL: beta-galactosidase 18 467 5.5E-180 T 16-09-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 Spa2297_RS01050 9136fdd9495cb4c1b1899c70268d939e 479 PANTHER PTHR10353:SF36 16 477 1.3E-199 T 16-09-2016 Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 SUPERFAMILY SSF53474 7 295 3.08E-42 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PANTHER PTHR24322 468 499 2.4E-56 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PANTHER PTHR24322 322 452 2.4E-56 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 SUPERFAMILY SSF51735 314 580 5.26E-70 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 455 483 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 Pfam PF00106 short chain dehydrogenase 319 509 9.0E-56 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 318 499 0.0082 T 16-09-2016 Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 Gene3D G3DSA:3.40.50.1820 6 295 4.5E-48 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 468 487 1.4E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 319 336 1.4E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 394 405 1.4E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 489 506 1.4E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 442 458 1.4E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 Gene3D G3DSA:3.40.50.720 317 555 3.7E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 468 487 1.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 448 456 1.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 394 405 1.3E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS16255 52061eda15bf9c9cca9a532c061068bf 585 Pfam PF00561 alpha/beta hydrolase fold 30 146 2.2E-18 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS06230 7632cf4e51db6056c3ad14372812e36a 231 PANTHER PTHR11922 33 231 2.0E-51 T 16-09-2016 Spa2297_RS06230 7632cf4e51db6056c3ad14372812e36a 231 Pfam PF07722 Peptidase C26 5 212 6.9E-66 T 16-09-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 Spa2297_RS06230 7632cf4e51db6056c3ad14372812e36a 231 Gene3D G3DSA:3.40.50.880 3 213 2.7E-41 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS06230 7632cf4e51db6056c3ad14372812e36a 231 SUPERFAMILY SSF52317 32 227 4.16E-38 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS06230 7632cf4e51db6056c3ad14372812e36a 231 PANTHER PTHR11922:SF18 33 231 2.0E-51 T 16-09-2016 Spa2297_RS31950 fb2acc82b145d5234b9d1646c6b8c6cd 302 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 44 57 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS31950 fb2acc82b145d5234b9d1646c6b8c6cd 302 PANTHER PTHR35344 1 74 5.1E-12 T 16-09-2016 Spa2297_RS31950 fb2acc82b145d5234b9d1646c6b8c6cd 302 PANTHER PTHR35344:SF1 1 74 5.1E-12 T 16-09-2016 Spa2297_RS31950 fb2acc82b145d5234b9d1646c6b8c6cd 302 Pfam PF00741 Gas vesicle protein 10 48 1.6E-10 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 PANTHER PTHR10799 479 952 9.8E-161 T 16-09-2016 Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 Pfam PF12419 SNF2 Helicase protein 311 447 6.6E-39 T 16-09-2016 IPR022138 Helicase SWF/SNF-related Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 Gene3D G3DSA:3.40.50.300 780 932 7.9E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 SUPERFAMILY SSF52540 472 701 7.98E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 SUPERFAMILY SSF52540 708 953 1.42E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 Pfam PF00176 SNF2 family N-terminal domain 510 770 3.6E-51 T 16-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 Pfam PF00271 Helicase conserved C-terminal domain 786 897 2.5E-17 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 SMART SM00490 815 897 3.3E-24 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 Gene3D G3DSA:3.40.50.300 487 655 1.2E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04195 a54dcfe83a8cece54eee35decabe7cce 958 SMART SM00487 488 674 5.4E-29 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 SUPERFAMILY SSF52091 169 278 7.46E-19 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 PANTHER PTHR33745 1 291 8.6E-86 T 16-09-2016 Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 Pfam PF01740 STAS domain 176 265 6.3E-9 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 PANTHER PTHR33745:SF1 1 291 8.6E-86 T 16-09-2016 Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 17 115 2.9E-15 T 16-09-2016 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain Spa2297_RS02060 debf2acf4693c3fd950ae96c35e54bf5 298 Gene3D G3DSA:3.30.750.24 170 262 5.8E-16 T 16-09-2016 IPR002645 STAS domain Spa2297_RS31970 dc181f861379c16841c903ebe3310aa8 318 PANTHER PTHR37955:SF1 1 315 2.5E-32 T 16-09-2016 Spa2297_RS31970 dc181f861379c16841c903ebe3310aa8 318 PANTHER PTHR37955 1 315 2.5E-32 T 16-09-2016 Spa2297_RS31970 dc181f861379c16841c903ebe3310aa8 318 Pfam PF03595 Voltage-dependent anion channel 8 304 1.0E-26 T 16-09-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Spa2297_RS29115 64a2b61c0a34bf4e8ab50ed789ad186f 123 Gene3D G3DSA:1.10.10.10 12 87 3.5E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29115 64a2b61c0a34bf4e8ab50ed789ad186f 123 SUPERFAMILY SSF46785 12 105 1.02E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29115 64a2b61c0a34bf4e8ab50ed789ad186f 123 Pfam PF12840 Helix-turn-helix domain 16 70 3.9E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29115 64a2b61c0a34bf4e8ab50ed789ad186f 123 SMART SM00418 16 103 2.1E-10 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 6.8E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 6.8E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 SUPERFAMILY SSF46689 19 99 4.84E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 Gene3D G3DSA:1.10.357.10 72 213 1.2E-17 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 PANTHER PTHR30055:SF80 15 220 5.0E-55 T 16-09-2016 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 71 6.6E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 Gene3D G3DSA:1.10.10.60 19 71 2.4E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13935 120bf5faaab760f2baa7e255d2056866 228 PANTHER PTHR30055 15 220 5.0E-55 T 16-09-2016 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 PANTHER PTHR30055 1 185 1.4E-44 T 16-09-2016 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.7E-17 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 PANTHER PTHR30055:SF11 1 185 1.4E-44 T 16-09-2016 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 Gene3D G3DSA:1.10.357.10 4 190 2.5E-32 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.7E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.7E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS18355 55a995969db349d3aefe10c42b07b185 195 SUPERFAMILY SSF46689 4 81 3.13E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Gene3D G3DSA:3.40.50.980 221 319 1.2E-28 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Gene3D G3DSA:3.40.50.980 375 436 1.2E-28 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Gene3D G3DSA:2.30.38.10 437 498 2.7E-17 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Gene3D G3DSA:3.30.300.30 505 625 3.1E-6 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 PANTHER PTHR24096 44 642 2.4E-198 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 SUPERFAMILY SSF56801 41 324 9.42E-112 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 SUPERFAMILY SSF56801 378 638 9.42E-112 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 PANTHER PTHR24096:SF193 44 642 2.4E-198 T 16-09-2016 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Pfam PF00501 AMP-binding enzyme 56 507 2.5E-92 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS11515 dd5b872c590044c3cb189257f1b39907 642 Gene3D G3DSA:3.40.50.980 49 220 4.6E-33 T 16-09-2016 Spa2297_RS03890 d3833ffbed5bfda641954318288989a1 132 SUPERFAMILY SSF103247 1 127 1.83E-36 T 16-09-2016 IPR005180 Domain of unknown function DUF302 Spa2297_RS03890 d3833ffbed5bfda641954318288989a1 132 Gene3D G3DSA:3.30.310.70 3 126 7.3E-48 T 16-09-2016 IPR005180 Domain of unknown function DUF302 Spa2297_RS03890 d3833ffbed5bfda641954318288989a1 132 PANTHER PTHR38342 1 129 3.8E-41 T 16-09-2016 Spa2297_RS03890 d3833ffbed5bfda641954318288989a1 132 PIRSF PIRSF021774 1 129 1.5E-45 T 16-09-2016 IPR016796 Uncharacterised conserved protein UCP021774 Spa2297_RS03890 d3833ffbed5bfda641954318288989a1 132 Pfam PF03625 Domain of unknown function DUF302 35 97 4.0E-27 T 16-09-2016 IPR005180 Domain of unknown function DUF302 Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 SUPERFAMILY SSF56601 205 224 5.83E-85 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 SUPERFAMILY SSF56601 253 624 5.83E-85 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 Gene3D G3DSA:1.10.3810.10 45 221 1.5E-62 T 16-09-2016 Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 PANTHER PTHR32282 1 732 0.0 T 16-09-2016 Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 Gene3D G3DSA:3.40.710.10 222 631 8.1E-100 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 SUPERFAMILY SSF53955 33 236 5.62E-60 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 Pfam PF00912 Transglycosylase 49 220 2.4E-55 T 16-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 PANTHER PTHR32282:SF8 1 732 0.0 T 16-09-2016 Spa2297_RS12380 ddbca95e8dc4678b14476a8d27b329a0 755 Pfam PF00905 Penicillin binding protein transpeptidase domain 322 580 3.9E-32 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 SUPERFAMILY SSF46894 144 217 7.82E-18 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 Gene3D G3DSA:3.40.50.2300 2 126 2.5E-14 T 16-09-2016 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.4E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 Gene3D G3DSA:1.10.10.10 135 215 1.6E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 PANTHER PTHR26402:SF547 3 220 4.6E-75 T 16-09-2016 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 SMART SM00421 153 210 2.2E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 SUPERFAMILY SSF52172 2 122 1.29E-12 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 PANTHER PTHR26402 3 220 4.6E-75 T 16-09-2016 Spa2297_RS13670 0a77e03d8d7fea0eea12d4cb71db4bba 224 Pfam PF00072 Response regulator receiver domain 6 106 3.3E-7 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 318 3.9E-117 T 16-09-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 Gene3D G3DSA:3.90.25.10 170 317 9.1E-44 T 16-09-2016 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 PANTHER PTHR10366:SF186 4 320 3.8E-106 T 16-09-2016 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 SUPERFAMILY SSF51735 1 315 4.96E-91 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 PANTHER PTHR10366 4 320 3.8E-106 T 16-09-2016 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 238 3.2E-57 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS13650 9e9b0356b3f42671c47d3cdcf5bd1da8 320 Gene3D G3DSA:3.40.50.720 3 169 3.5E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 PANTHER PTHR21666 217 373 7.5E-42 T 16-09-2016 Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 Gene3D G3DSA:2.70.70.10 240 373 1.2E-42 T 16-09-2016 Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 Pfam PF01551 Peptidase family M23 271 369 6.7E-28 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 SUPERFAMILY SSF51261 235 373 3.71E-46 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 Gene3D G3DSA:1.10.530.10 87 232 5.7E-12 T 16-09-2016 Spa2297_RS30890 ca348e3ffa7c39b64b128a6498f63a5d 377 SUPERFAMILY SSF53955 80 227 1.82E-15 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 ProSitePatterns PS01095 Chitinases family 18 active site. 383 391 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Pfam PF00041 Fibronectin type III domain 179 249 1.6E-8 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177 513 603 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Gene3D G3DSA:2.60.40.10 174 254 1.3E-20 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PRINTS PR00014 Fibronectin type III repeat signature 233 247 6.5E-5 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PRINTS PR00014 Fibronectin type III repeat signature 190 199 6.5E-5 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PRINTS PR00014 Fibronectin type III repeat signature 215 233 6.5E-5 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177:SF195 242 447 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177:SF195 466 494 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Gene3D G3DSA:2.60.120.260 42 166 1.4E-7 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Gene3D G3DSA:3.20.20.80 269 596 3.8E-63 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 SMART SM00636 271 588 1.9E-7 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177 242 447 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177 466 494 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Pfam PF00704 Glycosyl hydrolases family 18 273 588 3.1E-24 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 SMART SM00060 176 246 4.3E-13 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 SUPERFAMILY SSF51445 272 596 5.66E-54 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 SUPERFAMILY SSF49265 175 260 1.31E-19 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 Pfam PF02018 Carbohydrate binding domain 39 151 8.3E-13 T 16-09-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 PANTHER PTHR11177:SF195 513 603 2.9E-143 T 16-09-2016 Spa2297_RS24040 9d9e791be2a23030f5f9542871289a96 604 SUPERFAMILY SSF49785 38 168 3.49E-10 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 Gene3D G3DSA:3.30.1220.10 235 338 9.9E-18 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 SUPERFAMILY SSF52540 9 194 7.84E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 PANTHER PTHR13748:SF10 3 351 1.2E-119 T 16-09-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 248 338 3.5E-23 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 SMART SM00833 247 338 2.3E-15 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 PANTHER PTHR13748 3 351 1.2E-119 T 16-09-2016 Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 180 1.2E-42 T 16-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 Gene3D G3DSA:3.40.50.300 9 199 5.2E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24735 36a7bf365fa1b4e004e10713e715950c 372 SUPERFAMILY SSF90002 249 338 9.29E-18 T 16-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 Pfam PF01965 DJ-1/PfpI family 6 175 3.4E-30 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 Gene3D G3DSA:3.40.50.880 7 216 1.3E-58 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 Gene3D G3DSA:1.10.10.60 271 315 7.0E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 Gene3D G3DSA:1.10.10.60 217 267 2.6E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 PANTHER PTHR11019 55 320 2.9E-79 T 16-09-2016 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 SUPERFAMILY SSF46689 267 316 5.82E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 PANTHER PTHR11019:SF58 55 320 2.9E-79 T 16-09-2016 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 SMART SM00342 230 312 4.1E-18 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 Pfam PF12833 Helix-turn-helix domain 236 314 4.0E-19 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 SUPERFAMILY SSF46689 213 263 1.88E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18755 0f3f3e7e53390ed0a9354287d8576905 324 SUPERFAMILY SSF52317 6 195 4.12E-50 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 224 304 4.0E-8 T 16-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 187 250 3.5E-20 T 16-09-2016 IPR017703 YgfZ/GcvT conserved site Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 Gene3D G3DSA:3.30.70.1400 46 131 1.0E-11 T 16-09-2016 Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 Pfam PF01571 Aminomethyltransferase folate-binding domain 22 141 3.3E-18 T 16-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 SUPERFAMILY SSF103025 22 240 3.14E-52 T 16-09-2016 Spa2297_RS15275 9d7647d445a57f6a9ec663762e1a0b02 321 SUPERFAMILY SSF101790 243 309 4.74E-5 T 16-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 SMART SM00347 30 132 5.5E-18 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 108 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 Gene3D G3DSA:1.10.10.10 13 128 1.7E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 SUPERFAMILY SSF46785 12 129 1.66E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 Pfam PF12802 MarR family 35 99 1.1E-11 T 16-09-2016 Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 PANTHER PTHR33164 8 127 4.1E-19 T 16-09-2016 Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 2.1E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03150 bc2eb584ef7fd7e9c347f09a5750e50f 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 2.1E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 308 2.2E-86 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Gene3D G3DSA:3.40.190.10 2 108 6.5E-38 T 16-09-2016 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 306 9.7E-16 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 7.5E-19 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 7.5E-19 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 7.5E-19 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 7.5E-19 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 SUPERFAMILY SSF53850 5 220 4.07E-64 T 16-09-2016 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PANTHER PTHR11557:SF0 1 316 1.1E-115 T 16-09-2016 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PIRSF PIRSF001438 1 319 4.6E-108 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 213 5.8E-67 T 16-09-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 308 35.316 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Gene3D G3DSA:3.40.190.10 109 201 4.7E-32 T 16-09-2016 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 SUPERFAMILY SSF54782 222 316 3.79E-18 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 PANTHER PTHR11557 1 316 1.1E-115 T 16-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 Gene3D G3DSA:3.30.160.40 223 315 9.0E-22 T 16-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS18590 c4fe1b5612e0868d20103d4e454736cd 319 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 16-09-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 Gene3D G3DSA:3.40.50.1820 30 166 4.3E-40 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 Gene3D G3DSA:3.40.50.1820 209 273 4.3E-40 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 Pfam PF12697 Alpha/beta hydrolase family 56 263 3.6E-13 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 PANTHER PTHR10794 1 180 4.2E-69 T 16-09-2016 Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 SUPERFAMILY SSF53474 27 165 7.14E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 SUPERFAMILY SSF53474 209 272 7.14E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS15385 de2eceda5f40a740c4cc5c26a92a0f7b 278 PANTHER PTHR10794:SF46 1 180 4.2E-69 T 16-09-2016 Spa2297_RS06245 e5a1bb0d337cb44ec54a0452ec442c37 241 Gene3D G3DSA:3.40.50.1980 2 106 1.5E-19 T 16-09-2016 Spa2297_RS06245 e5a1bb0d337cb44ec54a0452ec442c37 241 SUPERFAMILY SSF53807 2 236 1.45E-33 T 16-09-2016 Spa2297_RS06245 e5a1bb0d337cb44ec54a0452ec442c37 241 Gene3D G3DSA:3.40.50.1980 130 236 2.2E-13 T 16-09-2016 Spa2297_RS06245 e5a1bb0d337cb44ec54a0452ec442c37 241 PANTHER PTHR30535:SF6 2 237 8.3E-116 T 16-09-2016 Spa2297_RS06245 e5a1bb0d337cb44ec54a0452ec442c37 241 PANTHER PTHR30535 2 237 8.3E-116 T 16-09-2016 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 Gene3D G3DSA:3.20.20.70 17 360 6.0E-55 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 PANTHER PTHR22976:SF4 7 371 1.0E-176 T 16-09-2016 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 6 371 49.681 T 16-09-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 SMART SM00729 56 270 0.0092 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 SUPERFAMILY SSF102114 16 361 1.44E-43 T 16-09-2016 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 Pfam PF04055 Radical SAM superfamily 61 231 2.8E-10 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 PIRSF PIRSF004762 1 378 2.3E-99 T 16-09-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 1.8E-91 T 16-09-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 367 2.3E-163 T 16-09-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS18860 8e773600303e6b3f9d528de712096fe5 387 PANTHER PTHR22976 7 371 1.0E-176 T 16-09-2016 Spa2297_RS06290 37c1d691bd37509d5a2ea6d208aff479 206 Pfam PF03029 Conserved hypothetical ATP binding protein 30 153 3.4E-23 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS06290 37c1d691bd37509d5a2ea6d208aff479 206 PANTHER PTHR11711 26 196 4.0E-58 T 16-09-2016 Spa2297_RS06290 37c1d691bd37509d5a2ea6d208aff479 206 Gene3D G3DSA:3.40.50.300 22 151 3.5E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06290 37c1d691bd37509d5a2ea6d208aff479 206 SUPERFAMILY SSF52540 25 196 4.51E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06290 37c1d691bd37509d5a2ea6d208aff479 206 PANTHER PTHR11711:SF117 26 196 4.0E-58 T 16-09-2016 Spa2297_RS24345 d7a8330f8419c1cc35f13fda407d74e1 126 SUPERFAMILY SSF47413 3 72 1.46E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS24345 d7a8330f8419c1cc35f13fda407d74e1 126 SMART SM00530 11 66 1.4E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS24345 d7a8330f8419c1cc35f13fda407d74e1 126 Gene3D G3DSA:1.10.260.40 8 75 5.6E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS24345 d7a8330f8419c1cc35f13fda407d74e1 126 Pfam PF13560 Helix-turn-helix domain 8 65 3.2E-11 T 16-09-2016 Spa2297_RS07925 2cf7eea3bacfedb718bc683f098af693 328 PANTHER PTHR30238:SF0 1 319 7.2E-166 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS07925 2cf7eea3bacfedb718bc683f098af693 328 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 2 307 9.4E-116 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS07925 2cf7eea3bacfedb718bc683f098af693 328 PANTHER PTHR30238 1 319 7.2E-166 T 16-09-2016 Spa2297_RS07925 2cf7eea3bacfedb718bc683f098af693 328 Pfam PF03741 Integral membrane protein TerC family 64 270 1.3E-54 T 16-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 Spa2297_RS31780 86ed537af25dc0c2137d58d3a1318feb 654 PANTHER PTHR39210 1 653 2.8E-135 T 16-09-2016 Spa2297_RS31780 86ed537af25dc0c2137d58d3a1318feb 654 SUPERFAMILY SSF48230 92 373 2.56E-29 T 16-09-2016 IPR008929 Chondroitin AC/alginate lyase Spa2297_RS31780 86ed537af25dc0c2137d58d3a1318feb 654 Pfam PF07940 Heparinase II/III-like protein 404 640 2.1E-46 T 16-09-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 Spa2297_RS31780 86ed537af25dc0c2137d58d3a1318feb 654 Gene3D G3DSA:1.50.10.110 90 335 2.4E-9 T 16-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Spa2297_RS31780 86ed537af25dc0c2137d58d3a1318feb 654 Pfam PF16889 Heparinase II/III N-terminus 123 323 1.5E-11 T 16-09-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 PANTHER PTHR34135:SF2 43 261 3.0E-81 T 16-09-2016 Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 SUPERFAMILY SSF51445 67 271 2.6E-63 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 PANTHER PTHR34135 43 261 3.0E-81 T 16-09-2016 Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 Pfam PF01183 Glycosyl hydrolases family 25 70 254 5.2E-53 T 16-09-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 SMART SM00641 67 176 1.3E-50 T 16-09-2016 IPR018077 Glycoside hydrolase, family 25 subgroup Spa2297_RS22335 c9d283ba8231e64e503f8e3f9b1e00c5 272 Gene3D G3DSA:3.20.20.80 67 271 1.3E-69 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 97 6.1E-23 T 16-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 Gene3D G3DSA:3.40.192.10 6 115 5.0E-32 T 16-09-2016 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 SUPERFAMILY SSF51735 111 279 2.44E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 SUPERFAMILY SSF53223 6 110 5.76E-25 T 16-09-2016 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 PANTHER PTHR21089 7 289 1.3E-55 T 16-09-2016 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 Gene3D G3DSA:3.40.50.720 116 279 1.1E-41 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 281 26.512 T 16-09-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS27670 2a8692732a980f0d6954de600daed5c1 292 PANTHER PTHR21089:SF8 7 289 1.3E-55 T 16-09-2016 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 PANTHER PTHR11271 8 442 5.4E-166 T 16-09-2016 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 SUPERFAMILY SSF51556 70 366 1.29E-78 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 Gene3D G3DSA:2.30.40.10 376 418 8.9E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 Gene3D G3DSA:2.30.40.10 8 72 8.9E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 Pfam PF01979 Amidohydrolase family 68 414 1.6E-53 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 PANTHER PTHR11271:SF7 8 442 5.4E-166 T 16-09-2016 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 SUPERFAMILY SSF51338 11 70 3.2E-28 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 SUPERFAMILY SSF51338 366 440 3.2E-28 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS08035 9c9b0a03b0851136574913f21c33aad1 454 Gene3D G3DSA:3.20.20.140 73 375 9.7E-80 T 16-09-2016 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 PANTHER PTHR10314:SF17 12 364 1.4E-151 T 16-09-2016 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 PANTHER PTHR10314 12 364 1.4E-151 T 16-09-2016 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 312 1.9E-81 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 Gene3D G3DSA:3.40.50.1100 80 329 5.4E-75 T 16-09-2016 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 SUPERFAMILY SSF53686 13 320 1.57E-92 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 16-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 Gene3D G3DSA:3.30.70.260 333 396 4.2E-4 T 16-09-2016 Spa2297_RS20980 8befe767d31a1a76d102641503619531 409 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 31 407 6.5E-134 T 16-09-2016 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00052 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 Pfam PF13394 4Fe-4S single cluster domain 37 116 1.8E-5 T 16-09-2016 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 Pfam PF11946 Domain of unknown function (DUF3463) 196 328 7.5E-56 T 16-09-2016 IPR022563 Domain of unknown function DUF3463 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 8.1E-162 T 16-09-2016 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 PANTHER PTHR11228 21 326 1.9E-103 T 16-09-2016 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 SUPERFAMILY SSF102114 23 308 3.01E-48 T 16-09-2016 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 SMART SM00729 28 225 0.0093 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 Pfam PF04055 Radical SAM superfamily 34 187 9.4E-18 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 PANTHER PTHR11228:SF22 21 326 1.9E-103 T 16-09-2016 Spa2297_RS28185 1198c3a166c31495ac5ec2228edee7b6 340 Gene3D G3DSA:3.20.20.70 18 310 4.1E-42 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 585 9.1E-131 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 PANTHER PTHR11956 4 585 8.7E-215 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 SUPERFAMILY SSF47323 464 585 2.03E-32 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Gene3D G3DSA:3.30.1360.70 5 106 3.1E-26 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Gene3D G3DSA:1.10.730.10 464 585 1.1E-33 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 126 137 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 SMART SM01016 9 89 9.5E-24 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 SUPERFAMILY SSF52374 114 464 3.04E-77 T 16-09-2016 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Pfam PF05746 DALR anticodon binding domain 470 585 7.3E-31 T 16-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 SMART SM00836 470 585 4.8E-38 T 16-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 SUPERFAMILY SSF55190 7 109 1.44E-16 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Pfam PF00750 tRNA synthetases class I (R) 118 455 1.0E-97 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 88 3.4E-17 T 16-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Gene3D G3DSA:3.40.50.620 119 462 5.4E-99 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 3.6E-20 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 3.6E-20 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 313 334 3.6E-20 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 3.6E-20 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS18635 b9f43f80c81d715e3d360de4518c9b4a 585 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 585 26.231 T 16-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 SUPERFAMILY SSF55816 400 606 1.7E-44 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PANTHER PTHR11575:SF7 56 282 1.2E-150 T 16-09-2016 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 Pfam PF00149 Calcineurin-like phosphoesterase 67 322 1.3E-4 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PANTHER PTHR11575 56 282 1.2E-150 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 Gene3D G3DSA:3.90.780.10 403 606 1.5E-46 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PRINTS PR01607 Apyrase family signature 60 78 5.1E-17 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PRINTS PR01607 Apyrase family signature 540 559 5.1E-17 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PRINTS PR01607 Apyrase family signature 305 328 5.1E-17 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PRINTS PR01607 Apyrase family signature 464 487 5.1E-17 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 Pfam PF02872 5'-nucleotidase, C-terminal domain 403 566 2.0E-38 T 16-09-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PANTHER PTHR11575:SF7 303 607 1.2E-150 T 16-09-2016 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 Gene3D G3DSA:3.60.21.10 58 393 7.7E-79 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 PANTHER PTHR11575 303 607 1.2E-150 T 16-09-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Spa2297_RS15415 0557103207b1865f589ea84ce9fd3e3e 607 SUPERFAMILY SSF56300 59 396 6.54E-67 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS02360 d65faac12ed4bef7a669cfb3a9c5f151 351 Gene3D G3DSA:1.10.540.10 6 114 1.3E-10 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS02360 d65faac12ed4bef7a669cfb3a9c5f151 351 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 113 2.1E-6 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS02360 d65faac12ed4bef7a669cfb3a9c5f151 351 Gene3D G3DSA:2.40.110.10 130 215 5.5E-7 T 16-09-2016 Spa2297_RS02360 d65faac12ed4bef7a669cfb3a9c5f151 351 SUPERFAMILY SSF56645 7 214 1.31E-26 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 PANTHER PTHR11921:SF13 3 249 7.5E-128 T 16-09-2016 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 Pfam PF13183 4Fe-4S dicluster domain 157 227 2.4E-10 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 4.6E-24 T 16-09-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 PANTHER PTHR11921 3 249 7.5E-128 T 16-09-2016 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 Gene3D G3DSA:1.10.1060.10 110 243 2.3E-20 T 16-09-2016 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 SUPERFAMILY SSF46548 118 241 2.62E-25 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 Gene3D G3DSA:3.10.20.30 1 109 4.1E-29 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS29025 d7342683c4ebf6c09ca51f499ec4d013 249 SUPERFAMILY SSF54292 2 115 1.66E-20 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 PANTHER PTHR11751 10 75 4.7E-15 T 16-09-2016 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 PANTHER PTHR11751 178 198 4.7E-15 T 16-09-2016 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 Gene3D G3DSA:1.10.10.10 10 75 8.7E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 7.6E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 7.6E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 SMART SM00345 12 72 1.6E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 65 3.9E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15235 70656e4758ef43bc1b300c261276a137 282 SUPERFAMILY SSF46785 9 65 1.13E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 PANTHER PTHR10359 28 227 5.8E-57 T 16-09-2016 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 SMART SM00478 57 209 1.1E-33 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 Gene3D G3DSA:1.10.1670.10 141 237 1.9E-33 T 16-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 SUPERFAMILY SSF48150 26 236 1.57E-59 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 167 7.0E-11 T 16-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 PANTHER PTHR10359:SF1 28 227 5.8E-57 T 16-09-2016 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 Pfam PF00633 Helix-hairpin-helix motif 117 146 1.5E-7 T 16-09-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 Gene3D G3DSA:1.10.340.30 40 140 5.9E-34 T 16-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 Spa2297_RS18395 c7f1a7655b2ec472d78574f80b3f9054 310 ProSitePatterns PS01155 Endonuclease III family signature. 120 149 - T 16-09-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 PANTHER PTHR30634:SF7 827 1222 0.0 T 16-09-2016 Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 PANTHER PTHR30634:SF7 17 654 0.0 T 16-09-2016 Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 PANTHER PTHR30634 827 1222 0.0 T 16-09-2016 Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 SUPERFAMILY SSF53300 1059 1210 7.79E-20 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 Pfam PF05762 VWA domain containing CoxE-like protein 997 1218 1.3E-59 T 16-09-2016 IPR008912 Uncharacterised protein family CoxE-like Spa2297_RS04270 d846e31880d4fc3cd41479dc1092f778 1223 PANTHER PTHR30634 17 654 0.0 T 16-09-2016 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.6E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 SUPERFAMILY SSF52172 3 129 7.26E-36 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.7E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.7E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.7E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 SUPERFAMILY SSF46894 144 218 2.18E-23 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 Gene3D G3DSA:1.10.10.10 126 220 1.9E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 Pfam PF00072 Response regulator receiver domain 5 119 3.4E-29 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 PANTHER PTHR26402 3 219 3.0E-131 T 16-09-2016 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 SMART SM00448 3 118 6.8E-37 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 Gene3D G3DSA:3.40.50.2300 3 125 5.9E-40 T 16-09-2016 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 SMART SM00421 155 212 1.7E-28 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS06420 14acdb3204ecfd76f6e821a6afca89c9 223 PANTHER PTHR26402:SF564 3 219 3.0E-131 T 16-09-2016 Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 PANTHER PTHR10584 9 300 3.0E-63 T 16-09-2016 Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 SUPERFAMILY SSF53613 9 301 9.82E-61 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 Gene3D G3DSA:3.40.1190.20 9 302 3.5E-62 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 PANTHER PTHR10584:SF166 9 300 3.0E-63 T 16-09-2016 Spa2297_RS07970 9e8ea0196ea9cb369e40bf774a3a011d 306 Pfam PF00294 pfkB family carbohydrate kinase 8 300 2.0E-50 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 PANTHER PTHR30385:SF4 28 280 1.1E-102 T 16-09-2016 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Gene3D G3DSA:1.10.10.10 126 181 5.8E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 PANTHER PTHR30385 28 280 1.1E-102 T 16-09-2016 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Pfam PF04542 Sigma-70 region 2 57 127 4.8E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 53 274 1.3E-31 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 51 276 1.3E-87 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Pfam PF04545 Sigma-70, region 4 226 274 3.1E-17 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Pfam PF04539 Sigma-70 region 3 137 203 1.3E-14 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 82 95 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 SUPERFAMILY SSF88659 131 207 3.14E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Gene3D G3DSA:1.10.601.10 43 125 7.9E-22 T 16-09-2016 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 PRINTS PR00046 Major sigma-70 factor signature 82 95 2.0E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 PRINTS PR00046 Major sigma-70 factor signature 229 241 2.0E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 PRINTS PR00046 Major sigma-70 factor signature 246 261 2.0E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 SUPERFAMILY SSF88659 194 276 3.36E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 Gene3D G3DSA:1.10.10.10 221 275 3.6E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31350 e1c48bca6587cb81c627935105e37c60 280 SUPERFAMILY SSF88946 18 127 4.71E-30 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 Gene3D G3DSA:1.10.230.10 222 306 4.6E-25 T 16-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PANTHER PTHR11739:SF14 3 366 1.1E-264 T 16-09-2016 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 16-09-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PANTHER PTHR11739 3 366 1.1E-264 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PRINTS PR00143 Citrate synthase signature 235 255 3.9E-26 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PRINTS PR00143 Citrate synthase signature 160 175 3.9E-26 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PRINTS PR00143 Citrate synthase signature 314 328 3.9E-26 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PRINTS PR00143 Citrate synthase signature 294 310 3.9E-26 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 PRINTS PR00143 Citrate synthase signature 182 210 3.9E-26 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 SUPERFAMILY SSF48256 3 355 8.24E-95 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 1.6E-83 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS14470 46d623e24558486fdc145f214b522573 366 Gene3D G3DSA:1.10.580.10 13 221 1.2E-46 T 16-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 Spa2297_RS28135 0377d3a2f6fd8835d7cbb9d27e36f0da 227 Pfam PF01066 CDP-alcohol phosphatidyltransferase 17 81 1.3E-9 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS28135 0377d3a2f6fd8835d7cbb9d27e36f0da 227 Gene3D G3DSA:1.20.200.10 90 158 2.8E-4 T 16-09-2016 Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 PANTHER PTHR11409:SF36 7 344 5.1E-171 T 16-09-2016 Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 21 341 4.3E-80 T 16-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 PANTHER PTHR11409 7 344 5.1E-171 T 16-09-2016 Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 SUPERFAMILY SSF51556 16 346 6.81E-75 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 Pfam PF00962 Adenosine/AMP deaminase 21 342 1.5E-95 T 16-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Spa2297_RS23910 c25a72c0e33235758950559735a17f57 353 Gene3D G3DSA:3.20.20.140 17 345 3.6E-95 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 SUPERFAMILY SSF51905 275 368 8.22E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 SUPERFAMILY SSF51905 1 175 8.22E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 SUPERFAMILY SSF54373 176 276 3.33E-41 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 Gene3D G3DSA:3.30.9.10 160 300 1.8E-64 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 Pfam PF01494 FAD binding domain 3 344 2.1E-79 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PANTHER PTHR13789:SF192 1 391 4.2E-213 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 Gene3D G3DSA:3.40.50.720 104 159 6.8E-10 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 Gene3D G3DSA:3.40.50.720 2 54 6.8E-10 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PANTHER PTHR13789 1 391 4.2E-213 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 329 1.3E-29 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.3E-29 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.3E-29 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.3E-29 T 16-09-2016 Spa2297_RS13400 0a3888b0fcb04d2333fe1c10670bf00d 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.3E-29 T 16-09-2016 Spa2297_RS03090 0c9262362939891cd8a7be89c8267e6a 322 PANTHER PTHR40111 2 318 9.5E-107 T 16-09-2016 Spa2297_RS03090 0c9262362939891cd8a7be89c8267e6a 322 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 319 3.7E-125 T 16-09-2016 IPR008391 Acetyl xylan esterase Spa2297_RS03090 0c9262362939891cd8a7be89c8267e6a 322 PANTHER PTHR40111:SF1 2 318 9.5E-107 T 16-09-2016 Spa2297_RS03090 0c9262362939891cd8a7be89c8267e6a 322 SUPERFAMILY SSF53474 2 315 1.71E-31 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03090 0c9262362939891cd8a7be89c8267e6a 322 Gene3D G3DSA:3.40.50.1820 1 320 5.0E-95 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 44 64 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 128 149 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 3 22 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 65 85 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 86 106 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 107 127 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PRINTS PR00601 Bacterioferritin signature 23 43 4.5E-54 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 Pfam PF00210 Ferritin-like domain 8 143 1.0E-30 T 16-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.0E-62 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 SUPERFAMILY SSF47240 1 154 9.98E-44 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PANTHER PTHR30295 6 160 2.9E-38 T 16-09-2016 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 PIRSF PIRSF002560 1 157 1.9E-64 T 16-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Spa2297_RS08675 6f0445191588a645875de36bf7cc5543 167 Gene3D G3DSA:1.20.1260.10 1 155 3.9E-52 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS08530 25126e252eaca9e27b1c5abc5186bac7 456 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 51 407 1.4E-114 T 16-09-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 Spa2297_RS08530 25126e252eaca9e27b1c5abc5186bac7 456 Pfam PF01098 Cell cycle protein 53 406 2.3E-93 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS08530 25126e252eaca9e27b1c5abc5186bac7 456 PANTHER PTHR30474:SF2 28 429 5.8E-154 T 16-09-2016 Spa2297_RS08530 25126e252eaca9e27b1c5abc5186bac7 456 PANTHER PTHR30474 28 429 5.8E-154 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS08530 25126e252eaca9e27b1c5abc5186bac7 456 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 366 390 - T 16-09-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 Spa2297_RS18735 0fe9058125d3a0c8df1a21f4d111edcc 406 PANTHER PTHR32468:SF9 7 384 1.7E-87 T 16-09-2016 Spa2297_RS18735 0fe9058125d3a0c8df1a21f4d111edcc 406 PANTHER PTHR32468 7 384 1.7E-87 T 16-09-2016 Spa2297_RS18735 0fe9058125d3a0c8df1a21f4d111edcc 406 Pfam PF00999 Sodium/hydrogen exchanger family 8 380 5.0E-55 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 Gene3D G3DSA:3.20.20.70 8 218 7.8E-73 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 Pfam PF02581 Thiamine monophosphate synthase/TENI 18 199 3.1E-51 T 16-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 15 217 24.047 T 16-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 PANTHER PTHR20857 5 218 5.5E-63 T 16-09-2016 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 17 211 5.4E-58 T 16-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 PANTHER PTHR20857:SF15 5 218 5.5E-63 T 16-09-2016 Spa2297_RS08625 954ebbcbe248b796983c810612a9ac60 219 SUPERFAMILY SSF51391 10 214 3.92E-60 T 16-09-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 PANTHER PTHR33993 2 248 1.8E-90 T 16-09-2016 Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 Gene3D G3DSA:3.10.180.10 22 132 3.5E-31 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 Gene3D G3DSA:3.10.180.10 146 247 1.3E-18 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 SUPERFAMILY SSF54593 24 173 5.09E-17 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 SUPERFAMILY SSF54593 146 247 3.66E-12 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14345 f5e1f0cd460acc504b6120899a23ffb8 248 PANTHER PTHR33993:SF3 2 248 1.8E-90 T 16-09-2016 Spa2297_RS07435 0b997197bdee63e68a707d2a2621ba2a 170 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 10 167 2.7E-61 T 16-09-2016 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178|UniPathway: UPA00067 Spa2297_RS07435 0b997197bdee63e68a707d2a2621ba2a 170 Pfam PF00583 Acetyltransferase (GNAT) family 58 131 2.9E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS07435 0b997197bdee63e68a707d2a2621ba2a 170 Gene3D G3DSA:3.40.630.30 8 167 5.3E-66 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS07435 0b997197bdee63e68a707d2a2621ba2a 170 SUPERFAMILY SSF55729 7 162 1.65E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 Pfam PF01008 Initiation factor 2 subunit family 86 359 2.0E-62 T 16-09-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 369 34.683 T 16-09-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 PANTHER PTHR10233 2 377 7.2E-152 T 16-09-2016 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 PANTHER PTHR10233:SF6 2 377 7.2E-152 T 16-09-2016 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 53 359 9.3E-82 T 16-09-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 SUPERFAMILY SSF100950 27 360 6.28E-95 T 16-09-2016 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 Gene3D G3DSA:1.20.120.420 30 172 3.6E-36 T 16-09-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 30 358 9.9E-104 T 16-09-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 Spa2297_RS13020 bab34ea1b45f0767e22d672a3b867b96 378 Gene3D G3DSA:3.40.50.10470 173 366 6.3E-59 T 16-09-2016 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 Gene3D G3DSA:1.10.1270.20 168 254 7.7E-27 T 16-09-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 SUPERFAMILY SSF75217 1 246 2.62E-81 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 237 9.3E-63 T 16-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 232 5.9E-72 T 16-09-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 PANTHER PTHR32125 1 239 5.4E-94 T 16-09-2016 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 277 99.358 T 16-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 PANTHER PTHR32125:SF1 1 239 5.4E-94 T 16-09-2016 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 PIRSF PIRSF000386 1 259 3.0E-93 T 16-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS23755 1e25519cbbc7ccef16e72c43d2b81696 277 Gene3D G3DSA:3.40.1280.10 1 167 2.1E-60 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 PANTHER PTHR30532:SF7 8 336 2.1E-64 T 16-09-2016 Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 SUPERFAMILY SSF53807 54 330 9.42E-51 T 16-09-2016 Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 PANTHER PTHR30532 8 336 2.1E-64 T 16-09-2016 Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 Gene3D G3DSA:3.40.50.1980 176 311 7.0E-18 T 16-09-2016 Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 Gene3D G3DSA:3.40.50.1980 50 175 1.0E-27 T 16-09-2016 Spa2297_RS01685 f5ae501e4272f54a3797191f6f31bee5 337 Pfam PF01497 Periplasmic binding protein 70 303 3.9E-23 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 Gene3D G3DSA:3.40.50.980 14 205 3.0E-37 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 Pfam PF00501 AMP-binding enzyme 21 489 2.3E-98 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 Gene3D G3DSA:3.40.50.980 356 418 5.9E-25 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 Gene3D G3DSA:3.40.50.980 206 297 5.9E-25 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 PANTHER PTHR24096 3 624 7.8E-186 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 SUPERFAMILY SSF56801 359 622 1.18E-117 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 SUPERFAMILY SSF56801 8 302 1.18E-117 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 PANTHER PTHR24096:SF46 3 624 7.8E-186 T 16-09-2016 Spa2297_RS10785 caeda281bed650b11ba119830f1f1488 625 Gene3D G3DSA:2.30.38.10 419 480 3.7E-22 T 16-09-2016 Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 SUPERFAMILY SSF53254 1 196 6.0E-49 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 PANTHER PTHR23029:SF23 1 198 1.9E-120 T 16-09-2016 Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 PANTHER PTHR23029 1 198 1.9E-120 T 16-09-2016 Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 Gene3D G3DSA:3.40.50.1240 3 197 1.4E-46 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 PIRSF PIRSF000709 1 178 7.0E-12 T 16-09-2016 Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 SMART SM00855 4 153 2.3E-21 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS11910 39bca8091191e426a7490f1b07b9bd75 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 192 4.5E-49 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS17135 3ac87808560a7f8cb5b20b306542a8cc 211 SUPERFAMILY SSF53448 8 188 3.09E-30 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS17135 3ac87808560a7f8cb5b20b306542a8cc 211 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 42 149 1.7E-22 T 16-09-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated Spa2297_RS17135 3ac87808560a7f8cb5b20b306542a8cc 211 PANTHER PTHR36529 1 211 3.7E-53 T 16-09-2016 Spa2297_RS17135 3ac87808560a7f8cb5b20b306542a8cc 211 Gene3D G3DSA:3.90.550.10 7 151 1.1E-24 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 SUPERFAMILY SSF48008 76 203 1.75E-19 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 4.7E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 SUPERFAMILY SSF46785 4 94 7.5E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 Gene3D G3DSA:1.20.120.530 72 202 9.4E-19 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 Gene3D G3DSA:1.10.10.10 3 69 1.1E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 PANTHER PTHR11751 5 94 3.1E-22 T 16-09-2016 Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 SMART SM00345 10 68 2.5E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 Pfam PF07729 FCD domain 79 201 2.7E-17 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS32140 ed66e89d956bb3c3486d3920509bf9c1 219 SMART SM00895 78 203 1.2E-10 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS06050 cb06eb2adcea9b42a7a39acd23c43cff 273 SMART SM00900 69 145 1.0E-11 T 16-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 Spa2297_RS06050 cb06eb2adcea9b42a7a39acd23c43cff 273 SMART SM00900 195 271 3.7E-11 T 16-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 Spa2297_RS06050 cb06eb2adcea9b42a7a39acd23c43cff 273 Pfam PF04205 FMN-binding domain 71 142 1.0E-8 T 16-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 Spa2297_RS06050 cb06eb2adcea9b42a7a39acd23c43cff 273 Pfam PF04205 FMN-binding domain 197 268 2.7E-9 T 16-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 Spa2297_RS27835 c394b99d0c050638b047cdd8ee2af9ee 145 Pfam PF00462 Glutaredoxin 70 127 8.8E-7 T 16-09-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Spa2297_RS27835 c394b99d0c050638b047cdd8ee2af9ee 145 PANTHER PTHR34386 30 143 3.9E-32 T 16-09-2016 Spa2297_RS27835 c394b99d0c050638b047cdd8ee2af9ee 145 Gene3D G3DSA:3.40.30.10 70 140 2.3E-8 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS27835 c394b99d0c050638b047cdd8ee2af9ee 145 SUPERFAMILY SSF52833 70 141 7.3E-10 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS27835 c394b99d0c050638b047cdd8ee2af9ee 145 PANTHER PTHR34386:SF1 30 143 3.9E-32 T 16-09-2016 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 SUPERFAMILY SSF56529 111 404 6.67E-86 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 SUPERFAMILY SSF63433 5 109 4.58E-25 T 16-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820 287 407 1.2E-145 T 16-09-2016 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820:SF1 287 407 1.2E-145 T 16-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820:SF1 109 265 1.2E-145 T 16-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820 1 83 1.2E-145 T 16-09-2016 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 115 403 1.6E-52 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 Gene3D G3DSA:2.30.30.230 5 111 3.2E-28 T 16-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 6 404 5.1E-121 T 16-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 Pfam PF09298 Fumarylacetoacetase N-terminal 15 109 4.9E-19 T 16-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 Gene3D G3DSA:3.90.850.10 112 399 2.5E-102 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820 109 265 1.2E-145 T 16-09-2016 Spa2297_RS19310 67a265ae0bdc6ac78fd5a470f6ab3729 408 PANTHER PTHR11820:SF1 1 83 1.2E-145 T 16-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 Gene3D G3DSA:3.40.50.9100 10 149 2.2E-63 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 10 148 3.0E-74 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 157 69.035 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 Pfam PF01220 Dehydroquinase class II 10 146 4.5E-58 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 10 147 5.3E-55 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 PANTHER PTHR21272 5 156 1.8E-88 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 SUPERFAMILY SSF52304 7 148 3.27E-60 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 ProSitePatterns PS01029 Dehydroquinase class II signature. 13 30 - T 16-09-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS07915 7d7216214f9f45150c60512bacf16960 157 PIRSF PIRSF001399 6 152 4.2E-61 T 16-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 Spa2297_RS06785 c6acdb911654f686cce632479b6d1a51 269 SUPERFAMILY SSF88713 27 198 4.2E-42 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS06785 c6acdb911654f686cce632479b6d1a51 269 Gene3D G3DSA:3.20.20.370 42 195 5.8E-34 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS06785 c6acdb911654f686cce632479b6d1a51 269 Pfam PF01522 Polysaccharide deacetylase 64 194 2.1E-33 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS06785 c6acdb911654f686cce632479b6d1a51 269 PANTHER PTHR34216 1 262 2.7E-60 T 16-09-2016 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 Gene3D G3DSA:1.10.10.10 151 216 1.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 SMART SM00421 149 211 1.8E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 SMART SM00448 1 120 3.1E-8 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 Gene3D G3DSA:3.40.50.2300 2 150 5.9E-26 T 16-09-2016 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 196 4.4E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 Pfam PF00072 Response regulator receiver domain 3 117 4.1E-12 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 PANTHER PTHR26402 1 210 9.4E-119 T 16-09-2016 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 SUPERFAMILY SSF52172 1 177 1.57E-18 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 PANTHER PTHR26402:SF582 1 210 9.4E-119 T 16-09-2016 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09250 4b896fbbb9573e508c29353106b4b7d6 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.3E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Gene3D G3DSA:1.20.140.10 232 393 2.0E-40 T 16-09-2016 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 134 9.0E-24 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 PANTHER PTHR10909 10 392 2.8E-174 T 16-09-2016 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 PANTHER PTHR10909:SF280 10 392 2.8E-174 T 16-09-2016 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 390 2.3E-27 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Gene3D G3DSA:1.10.540.10 7 135 2.3E-32 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Gene3D G3DSA:2.40.110.10 137 231 4.7E-30 T 16-09-2016 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 230 1.1E-20 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 SUPERFAMILY SSF56645 11 243 2.36E-62 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS31900 9d65ac96e10f7308a20b18f3e699066e 397 SUPERFAMILY SSF47203 245 394 4.03E-40 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 SUPERFAMILY SSF51735 1 143 7.01E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 290 8.9E-102 T 16-09-2016 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 SUPERFAMILY SSF48179 158 290 5.51E-42 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 SMART SM01350 160 287 2.9E-6 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PANTHER PTHR11811:SF28 1 289 1.4E-164 T 16-09-2016 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 1.5E-38 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PANTHER PTHR11811 1 289 1.4E-164 T 16-09-2016 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 Gene3D G3DSA:3.40.50.720 1 161 2.0E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 5.3E-26 T 16-09-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 Gene3D G3DSA:1.10.1040.10 162 270 5.0E-36 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 3.6E-38 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 3.6E-38 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 3.6E-38 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 3.6E-38 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS27685 680479c5fdf262b60085b49be3eb89e4 293 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 3.6E-38 T 16-09-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 SUPERFAMILY SSF51905 49 378 8.26E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 SUPERFAMILY SSF51905 500 540 8.26E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Pfam PF01593 Flavin containing amine oxidoreductase 59 534 5.6E-46 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 SUPERFAMILY SSF54373 363 478 4.64E-27 T 16-09-2016 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 PRINTS PR00757 Flavin-containing amine oxidase signature 51 70 7.4E-5 T 16-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 PRINTS PR00757 Flavin-containing amine oxidase signature 251 273 7.4E-5 T 16-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Gene3D G3DSA:3.50.50.60 48 79 1.4E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 PANTHER PTHR10742 14 560 8.9E-134 T 16-09-2016 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Gene3D G3DSA:3.90.660.10 367 469 2.5E-27 T 16-09-2016 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Gene3D G3DSA:3.90.660.10 80 154 2.5E-27 T 16-09-2016 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 PANTHER PTHR10742:SF277 14 560 8.9E-134 T 16-09-2016 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Gene3D G3DSA:3.50.50.60 248 363 3.7E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05485 d6e6dac7d641c5cbe700389fa9cfbdf7 565 Gene3D G3DSA:3.50.50.60 503 544 3.7E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 PANTHER PTHR22935:SF55 273 533 8.3E-119 T 16-09-2016 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 Gene3D G3DSA:2.30.40.10 3 74 1.2E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 PANTHER PTHR22935 273 533 8.3E-119 T 16-09-2016 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 Gene3D G3DSA:3.20.20.140 75 291 9.9E-115 T 16-09-2016 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 Gene3D G3DSA:3.20.20.140 396 456 9.9E-115 T 16-09-2016 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 SUPERFAMILY SSF51556 62 299 8.81E-77 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 SUPERFAMILY SSF51556 344 472 8.81E-77 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 Pfam PF07969 Amidohydrolase family 51 516 2.2E-65 T 16-09-2016 IPR013108 Amidohydrolase 3 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 Gene3D G3DSA:2.30.40.10 457 522 2.3E-10 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 SUPERFAMILY SSF51338 2 62 1.54E-20 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS21105 5c734ae38aa8b8c8fdfd18eaeba8e13d 536 SUPERFAMILY SSF51338 472 523 1.54E-20 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS15165 56a12914667a18747867a8d0f66d3273 167 SUPERFAMILY SSF69635 5 133 3.56E-31 T 16-09-2016 Spa2297_RS15165 56a12914667a18747867a8d0f66d3273 167 Pfam PF10722 Putative bacterial sensory transduction regulator 8 131 1.1E-19 T 16-09-2016 IPR019660 Putative sensory transduction regulator YbjN Spa2297_RS15165 56a12914667a18747867a8d0f66d3273 167 Gene3D G3DSA:3.30.1460.10 10 143 2.2E-15 T 16-09-2016 Spa2297_RS27410 8524f534d825dcddae6bad3c9b52ede6 407 Pfam PF01261 Xylose isomerase-like TIM barrel 119 356 2.3E-43 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27410 8524f534d825dcddae6bad3c9b52ede6 407 Gene3D G3DSA:3.20.20.150 90 393 7.1E-45 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27410 8524f534d825dcddae6bad3c9b52ede6 407 SUPERFAMILY SSF51658 114 405 4.98E-30 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27410 8524f534d825dcddae6bad3c9b52ede6 407 PANTHER PTHR40117 316 406 1.6E-91 T 16-09-2016 Spa2297_RS27410 8524f534d825dcddae6bad3c9b52ede6 407 PANTHER PTHR40117 7 298 1.6E-91 T 16-09-2016 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 Gene3D G3DSA:2.60.40.290 264 354 5.2E-26 T 16-09-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 PANTHER PTHR34823:SF2 1 231 1.5E-44 T 16-09-2016 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 Gene3D G3DSA:2.70.50.50 35 228 1.0E-43 T 16-09-2016 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 SUPERFAMILY SSF81296 35 229 5.6E-41 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 SMART SM00637 265 361 1.5E-31 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 Pfam PF00553 Cellulose binding domain 265 353 3.1E-20 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 SUPERFAMILY SSF49384 259 356 6.98E-26 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 225 1.3E-36 T 16-09-2016 IPR004302 Chitin-binding protein, N-terminal Spa2297_RS04290 3c973d3e648698b423474b9ed5d472f8 364 PANTHER PTHR34823 1 231 1.5E-44 T 16-09-2016 Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 Gene3D G3DSA:1.20.1250.20 286 458 1.1E-10 T 16-09-2016 Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 Gene3D G3DSA:1.20.1250.20 24 203 1.2E-26 T 16-09-2016 Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 SUPERFAMILY SSF103473 16 209 9.16E-51 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 SUPERFAMILY SSF103473 262 459 9.16E-51 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 Pfam PF07690 Major Facilitator Superfamily 28 421 8.4E-40 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS31240 4167d11d67a75fc7b5d5df9659ec3c9f 474 PANTHER PTHR23501 27 472 9.3E-69 T 16-09-2016 Spa2297_RS23815 5b7aead61f396f4ae577e4cecf1d58fb 193 Gene3D G3DSA:2.70.70.10 23 147 5.5E-23 T 16-09-2016 Spa2297_RS23815 5b7aead61f396f4ae577e4cecf1d58fb 193 PANTHER PTHR21666:SF190 14 169 1.9E-37 T 16-09-2016 Spa2297_RS23815 5b7aead61f396f4ae577e4cecf1d58fb 193 PANTHER PTHR21666 14 169 1.9E-37 T 16-09-2016 Spa2297_RS23815 5b7aead61f396f4ae577e4cecf1d58fb 193 SUPERFAMILY SSF51261 22 146 1.15E-15 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS23815 5b7aead61f396f4ae577e4cecf1d58fb 193 Pfam PF01551 Peptidase family M23 46 142 6.8E-15 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 40 337 3.4E-33 T 16-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 Gene3D G3DSA:3.30.1780.10 23 163 5.1E-41 T 16-09-2016 IPR023401 Ornithine cyclodeaminase, N-terminal Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 23 348 1.2E-123 T 16-09-2016 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 Gene3D G3DSA:3.40.50.720 164 318 2.6E-13 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 SUPERFAMILY SSF51735 23 347 1.72E-60 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 PANTHER PTHR13812 9 350 2.4E-29 T 16-09-2016 Spa2297_RS00675 23a34fba4934f67cbee823cb0ce6ae5b 356 PIRSF PIRSF001439 17 348 3.7E-78 T 16-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PANTHER PTHR23501 15 431 2.3E-196 T 16-09-2016 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PRINTS PR01035 Tetracycline resistance protein signature 33 49 1.4E-12 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PRINTS PR01035 Tetracycline resistance protein signature 147 169 1.4E-12 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PRINTS PR01035 Tetracycline resistance protein signature 367 386 1.4E-12 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PRINTS PR01035 Tetracycline resistance protein signature 175 195 1.4E-12 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Pfam PF00582 Universal stress protein family 422 557 4.6E-9 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Gene3D G3DSA:3.40.50.620 413 557 3.5E-13 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 SUPERFAMILY SSF52402 422 561 1.76E-12 T 16-09-2016 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Pfam PF07690 Major Facilitator Superfamily 247 393 9.0E-9 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Pfam PF07690 Major Facilitator Superfamily 28 241 1.7E-28 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Gene3D G3DSA:1.20.1250.20 22 203 6.4E-27 T 16-09-2016 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 Gene3D G3DSA:1.20.1250.20 215 391 9.8E-14 T 16-09-2016 Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 SUPERFAMILY SSF103473 20 392 2.35E-56 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01615 4bdbd1f7f18c49a2979739e178b8ed24 578 PANTHER PTHR23501:SF72 15 431 2.3E-196 T 16-09-2016 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 PANTHER PTHR30173:SF17 146 366 1.5E-43 T 16-09-2016 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 Gene3D G3DSA:1.10.260.40 16 63 1.1E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 Pfam PF13560 Helix-turn-helix domain 16 72 5.7E-9 T 16-09-2016 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 SUPERFAMILY SSF47413 16 63 1.49E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 SMART SM00530 16 68 3.0E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 PANTHER PTHR30173 146 366 1.5E-43 T 16-09-2016 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 Gene3D G3DSA:1.10.1740.10 169 239 3.5E-6 T 16-09-2016 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 SUPERFAMILY SSF88946 169 235 8.63E-7 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 Gene3D G3DSA:1.10.10.10 257 315 9.8E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20305 8fa7eb78076385fb5ae9a6bab128ba0b 429 SUPERFAMILY SSF88659 258 313 5.23E-7 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 Gene3D G3DSA:2.60.120.200 39 284 6.0E-74 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 SUPERFAMILY SSF49899 35 284 6.7E-70 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 PANTHER PTHR10963 47 283 2.9E-64 T 16-09-2016 Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 Gene3D G3DSA:2.80.10.50 285 413 1.0E-44 T 16-09-2016 Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 SMART SM00458 287 414 5.4E-34 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 SUPERFAMILY SSF50370 286 413 5.22E-42 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 Pfam PF00652 Ricin-type beta-trefoil lectin domain 291 411 2.5E-32 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29770 e00a2ae45d7b9117a9c3cbd66066d35e 414 Pfam PF00722 Glycosyl hydrolases family 16 77 266 8.0E-42 T 16-09-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 SMART SM00344 2 109 7.1E-28 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 Gene3D G3DSA:1.10.10.10 4 54 1.1E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 3.6E-16 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 SUPERFAMILY SSF46785 2 62 3.46E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 16-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 Gene3D G3DSA:3.30.70.920 55 134 1.9E-19 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 SUPERFAMILY SSF54909 64 142 1.88E-12 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 138 9.0E-14 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 PANTHER PTHR30154:SF26 2 144 1.3E-92 T 16-09-2016 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 6.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 6.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 6.3E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS05500 a6ba288c4201b6ff6ae26f8be48c8ea5 150 PANTHER PTHR30154 2 144 1.3E-92 T 16-09-2016 Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 40 170 32.488 T 16-09-2016 IPR023035 Ribosomal protein S9, bacterial/plastid Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 SUPERFAMILY SSF54211 46 170 9.86E-42 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 PANTHER PTHR21569 43 170 4.2E-57 T 16-09-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 ProSitePatterns PS00360 Ribosomal protein S9 signature. 108 126 - T 16-09-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 Pfam PF00380 Ribosomal protein S9/S16 49 170 6.5E-43 T 16-09-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19960 cef0c4562b5cd0da75978539b6c81313 170 Gene3D G3DSA:3.30.230.10 46 170 1.2E-46 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PANTHER PTHR10992 4 275 8.0E-84 T 16-09-2016 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 Pfam PF12697 Alpha/beta hydrolase family 30 267 5.4E-19 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PANTHER PTHR10992:SF830 4 275 8.0E-84 T 16-09-2016 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00412 Epoxide hydrolase signature 98 111 1.2E-5 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00412 Epoxide hydrolase signature 250 272 1.2E-5 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00412 Epoxide hydrolase signature 34 52 1.2E-5 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 2.1E-11 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.1E-11 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 2.1E-11 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 SUPERFAMILY SSF53474 15 275 4.48E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30990 96d881ca112768aa289f4dfc896c56df 277 Gene3D G3DSA:3.40.50.1820 16 275 4.2E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 SUPERFAMILY SSF47413 8 69 1.34E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 PANTHER PTHR10245:SF36 8 124 2.0E-69 T 16-09-2016 Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 Gene3D G3DSA:1.10.260.40 8 109 9.0E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 Pfam PF01381 Helix-turn-helix 13 65 6.2E-15 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 PANTHER PTHR10245 8 124 2.0E-69 T 16-09-2016 Spa2297_RS15205 d531ce16d1787dc5944b4b6a515cd303 139 SMART SM00530 12 67 1.0E-15 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 276 2.0E-53 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 Gene3D G3DSA:3.10.310.10 122 266 2.8E-39 T 16-09-2016 Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 PIRSF PIRSF016184 1 278 3.9E-62 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 Pfam PF02567 Phenazine biosynthesis-like protein 6 277 8.0E-67 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 PANTHER PTHR13774:SF21 1 278 1.9E-69 T 16-09-2016 Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 SUPERFAMILY SSF54506 2 277 5.23E-58 T 16-09-2016 Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 PANTHER PTHR13774 1 278 1.9E-69 T 16-09-2016 Spa2297_RS28560 d1e1895a1b16d68bb933d7d3b25094b8 278 Gene3D G3DSA:3.10.310.10 2 121 2.4E-37 T 16-09-2016 Spa2297_RS27385 6a334f49d19f462fc914c2431e1f0e8e 310 Pfam PF01261 Xylose isomerase-like TIM barrel 40 251 6.4E-35 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27385 6a334f49d19f462fc914c2431e1f0e8e 310 Gene3D G3DSA:3.20.20.150 21 294 6.2E-59 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27385 6a334f49d19f462fc914c2431e1f0e8e 310 PANTHER PTHR12110 15 307 3.3E-82 T 16-09-2016 Spa2297_RS27385 6a334f49d19f462fc914c2431e1f0e8e 310 SUPERFAMILY SSF51658 16 294 4.58E-60 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27385 6a334f49d19f462fc914c2431e1f0e8e 310 PANTHER PTHR12110:SF21 15 307 3.3E-82 T 16-09-2016 Spa2297_RS00595 7ee81151a65f0bf2b240ca5806ef6b3c 260 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 233 1.3E-42 T 16-09-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 Spa2297_RS00595 7ee81151a65f0bf2b240ca5806ef6b3c 260 PANTHER PTHR36925 1 249 1.6E-78 T 16-09-2016 Spa2297_RS00595 7ee81151a65f0bf2b240ca5806ef6b3c 260 Gene3D G3DSA:3.40.50.2300 185 235 1.3E-4 T 16-09-2016 Spa2297_RS00595 7ee81151a65f0bf2b240ca5806ef6b3c 260 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 229 1.7E-69 T 16-09-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 Pfam PF13796 Putative sensor 29 202 9.7E-21 T 16-09-2016 IPR025828 Putative sensor domain Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 PANTHER PTHR24421 208 418 1.6E-67 T 16-09-2016 Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 PANTHER PTHR24421:SF19 208 418 1.6E-67 T 16-09-2016 Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 Gene3D G3DSA:3.30.565.10 337 418 1.2E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 SUPERFAMILY SSF55874 319 417 2.49E-14 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 Pfam PF07730 Histidine kinase 230 297 2.9E-15 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 SMART SM00387 330 419 0.0021 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS09245 ef7db8d450d9d172d65855f83f658327 419 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 376 3.4E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23285 6530704b56c45c7c31dbe22bf08b9153 194 SUPERFAMILY SSF55729 8 175 4.48E-34 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS23285 6530704b56c45c7c31dbe22bf08b9153 194 PANTHER PTHR13256:SF22 12 185 2.5E-46 T 16-09-2016 Spa2297_RS23285 6530704b56c45c7c31dbe22bf08b9153 194 Gene3D G3DSA:3.40.630.30 9 176 3.8E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS23285 6530704b56c45c7c31dbe22bf08b9153 194 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 6.3E-14 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS23285 6530704b56c45c7c31dbe22bf08b9153 194 PANTHER PTHR13256 12 185 2.5E-46 T 16-09-2016 Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 PANTHER PTHR23513:SF9 12 438 4.3E-173 T 16-09-2016 Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 SUPERFAMILY SSF103473 29 413 1.57E-38 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 PANTHER PTHR23513 12 438 4.3E-173 T 16-09-2016 Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 Pfam PF05977 Transmembrane secretion effector 23 422 1.3E-31 T 16-09-2016 IPR010290 Transmembrane secretion effector Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 Gene3D G3DSA:1.20.1250.20 29 208 6.2E-15 T 16-09-2016 Spa2297_RS09450 e888dffa0ccad01e7a2a59b9d0b54649 439 Gene3D G3DSA:1.20.1250.20 247 412 1.8E-14 T 16-09-2016 Spa2297_RS14615 cded1e86658517f5bf8314c4468dfe7e 60 SUPERFAMILY SSF47598 4 39 1.11E-6 T 16-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 Spa2297_RS14615 cded1e86658517f5bf8314c4468dfe7e 60 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 29 2.6E-4 T 16-09-2016 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 4.9E-126 T 16-09-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 SUPERFAMILY SSF52402 485 624 3.03E-71 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 SUPERFAMILY SSF52402 241 387 3.03E-71 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 PANTHER PTHR11772:SF10 476 641 3.8E-182 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 PIRSF PIRSF001589 1 644 9.8E-152 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 Gene3D G3DSA:3.60.20.10 18 222 5.3E-75 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 PANTHER PTHR11772 476 641 3.8E-182 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 Pfam PF13537 Glutamine amidotransferase domain 48 165 3.5E-42 T 16-09-2016 IPR017932 Glutamine amidotransferase type 2 domain Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 SUPERFAMILY SSF56235 1 223 6.0E-60 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 Pfam PF00733 Asparagine synthase 242 630 2.2E-93 T 16-09-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 PANTHER PTHR11772 2 389 3.8E-182 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 PANTHER PTHR11772:SF10 2 389 3.8E-182 T 16-09-2016 Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 Gene3D G3DSA:3.40.50.620 223 383 1.7E-76 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS31790 09daae306cac926db253a34b5e8d43b6 644 Gene3D G3DSA:3.40.50.620 480 630 1.7E-76 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 Pfam PF01478 Type IV leader peptidase family 229 339 3.2E-18 T 16-09-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 294 304 7.4E-6 T 16-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 305 316 7.4E-6 T 16-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 237 254 7.4E-6 T 16-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 PANTHER PTHR30487:SF0 205 373 3.9E-37 T 16-09-2016 Spa2297_RS19150 e07a76270fb6adc63aad5cb7e966723b 375 PANTHER PTHR30487 205 373 3.9E-37 T 16-09-2016 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 659 1003 4.9E-62 T 16-09-2016 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 Gene3D G3DSA:1.20.1270.50 522 619 1.0E-20 T 16-09-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 PANTHER PTHR11607 168 983 0.0 T 16-09-2016 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 SUPERFAMILY SSF74650 659 1005 4.39E-60 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 SMART SM00872 519 597 1.6E-37 T 16-09-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 255 510 2.0E-85 T 16-09-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 PANTHER PTHR11607:SF15 168 983 0.0 T 16-09-2016 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 Pfam PF09261 Alpha mannosidase middle domain 519 596 1.0E-25 T 16-09-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 SUPERFAMILY SSF88713 248 517 3.11E-77 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 Gene3D G3DSA:3.20.110.10 203 521 1.1E-86 T 16-09-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain Spa2297_RS28915 6619578546b105863ff8cf5b24ab6000 1007 SUPERFAMILY SSF88688 518 624 5.89E-25 T 16-09-2016 IPR028995 Glycoside hydrolase families 57/38, central domain Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 Gene3D G3DSA:3.40.50.2300 42 167 1.2E-20 T 16-09-2016 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 Pfam PF13377 Periplasmic binding protein-like domain 163 309 6.7E-13 T 16-09-2016 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 Gene3D G3DSA:3.40.50.2300 168 299 3.4E-16 T 16-09-2016 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 PANTHER PTHR30146:SF30 1 306 7.3E-60 T 16-09-2016 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 36 1.8E-4 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 PANTHER PTHR30146 1 306 7.3E-60 T 16-09-2016 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 SUPERFAMILY SSF53822 64 309 2.03E-24 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 SMART SM00354 1 59 0.0037 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS30540 152dba57d27b98065b69445d98dfe6ee 329 Gene3D G3DSA:1.10.260.40 1 41 4.2E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Gene3D G3DSA:3.40.50.970 2 181 8.5E-57 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 PANTHER PTHR18968 5 592 3.0E-227 T 16-09-2016 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 2.4E-27 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 SUPERFAMILY SSF52518 4 181 9.38E-47 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 329 7.1E-28 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 SUPERFAMILY SSF52518 365 561 7.33E-51 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 PANTHER PTHR18968:SF124 5 592 3.0E-227 T 16-09-2016 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Gene3D G3DSA:3.40.50.1220 193 353 1.9E-42 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 SUPERFAMILY SSF52467 160 358 6.25E-44 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 9.6E-46 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 16-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spa2297_RS31845 78d7732166249b4d23f321fba9115a53 614 Gene3D G3DSA:3.40.50.970 359 569 1.6E-51 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 Pfam PF09364 XFP N-terminal domain 12 388 1.8E-180 T 16-09-2016 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 Pfam PF09363 XFP C-terminal domain 590 792 2.4E-84 T 16-09-2016 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 Gene3D G3DSA:3.40.50.970 57 259 6.9E-21 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 Hamap MF_01403 Probable phosphoketolase. 9 794 40.834 T 16-09-2016 IPR023962 Probable phosphoketolase Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 SUPERFAMILY SSF52518 7 373 3.54E-74 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 PANTHER PTHR31273 1 796 0.0 T 16-09-2016 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 403 579 7.4E-85 T 16-09-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 SUPERFAMILY SSF52518 380 592 1.06E-22 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 ProSitePatterns PS60002 Phosphoketolase signature 1. 148 154 - T 16-09-2016 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 ProSitePatterns PS60003 Phosphoketolase signature 2. 161 179 - T 16-09-2016 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 PANTHER PTHR31273:SF0 1 796 0.0 T 16-09-2016 Spa2297_RS30580 c25bed1d8eb9a7c92894f01d5c91828f 796 PIRSF PIRSF017245 2 794 0.0 T 16-09-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 SMART SM00866 109 249 2.9E-18 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 SUPERFAMILY SSF46785 3 74 3.66E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 Gene3D G3DSA:1.10.10.10 3 70 2.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 SMART SM00345 11 70 1.0E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 4.1E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 SUPERFAMILY SSF64288 58 255 9.58E-29 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 Gene3D G3DSA:3.40.1410.10 71 252 6.1E-50 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS12680 3f2b8dfde7689eff11d191652b9dc60d 267 Pfam PF07702 UTRA domain 116 248 5.2E-23 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 Pfam PF04542 Sigma-70 region 2 16 84 6.9E-16 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 Gene3D G3DSA:1.10.1740.10 9 106 1.1E-21 T 16-09-2016 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 PANTHER PTHR30173:SF17 1 170 6.8E-74 T 16-09-2016 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 Gene3D G3DSA:1.10.10.10 110 169 5.8E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 Pfam PF04545 Sigma-70, region 4 116 164 7.2E-14 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 39 71 - T 16-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 PANTHER PTHR30173 1 170 6.8E-74 T 16-09-2016 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 SUPERFAMILY SSF88659 98 169 3.05E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 SUPERFAMILY SSF88946 7 99 1.61E-20 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12765 2a74d9871a7c54ad4ef04dfb8716ecd8 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 166 6.1E-25 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 Pfam PF02622 Uncharacterized ACR, COG1678 16 173 2.3E-36 T 16-09-2016 IPR003774 Protein of unknown function UPF0301 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 187 26.828 T 16-09-2016 IPR003774 Protein of unknown function UPF0301 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 PANTHER PTHR30327:SF1 1 190 6.5E-62 T 16-09-2016 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 Gene3D G3DSA:3.40.1740.10 2 44 7.9E-29 T 16-09-2016 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 Gene3D G3DSA:3.40.1740.10 131 177 7.9E-29 T 16-09-2016 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 SUPERFAMILY SSF143456 4 184 3.4E-47 T 16-09-2016 Spa2297_RS12735 d4884b185cef828ce9b0699b2f942795 190 PANTHER PTHR30327 1 190 6.5E-62 T 16-09-2016 Spa2297_RS17590 6eb7e54ca2b49370dca26d576675c4cb 171 SUPERFAMILY SSF58113 14 107 7.45E-6 T 16-09-2016 Spa2297_RS17590 6eb7e54ca2b49370dca26d576675c4cb 171 Pfam PF12277 Protein of unknown function (DUF3618) 12 56 9.1E-15 T 16-09-2016 IPR022062 Protein of unknown function DUF3618 Spa2297_RS17590 6eb7e54ca2b49370dca26d576675c4cb 171 Gene3D G3DSA:1.20.120.20 16 100 0.001 T 16-09-2016 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 SUPERFAMILY SSF51905 1 199 2.46E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 SUPERFAMILY SSF51905 292 342 2.46E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 Gene3D G3DSA:3.50.50.60 1 68 2.8E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 Gene3D G3DSA:3.50.50.60 118 198 2.8E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 Gene3D G3DSA:3.50.50.60 292 338 2.8E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 PANTHER PTHR13847 2 346 1.6E-26 T 16-09-2016 Spa2297_RS28265 0cbd62cc075f9e1f2a6733fa77224c62 368 Pfam PF01266 FAD dependent oxidoreductase 2 330 9.3E-41 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 445 7.9E-21 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 6.3E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 6.3E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 249 263 6.3E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 6.3E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 6.3E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PANTHER PTHR22912 1 455 1.6E-162 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 SUPERFAMILY SSF51905 153 332 9.39E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PANTHER PTHR22912:SF140 1 455 1.6E-162 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 Gene3D G3DSA:3.30.390.30 349 457 2.4E-37 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 SUPERFAMILY SSF51905 12 208 1.13E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 Gene3D G3DSA:3.50.50.60 128 328 3.1E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 SUPERFAMILY SSF55424 337 457 7.39E-32 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 321 4.6E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 Gene3D G3DSA:3.50.50.60 10 127 1.7E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 3.2E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.2E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 3.2E-18 T 16-09-2016 Spa2297_RS25405 0bfd1c7a53dd600e1eafec4da16ff13c 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 3.2E-18 T 16-09-2016 Spa2297_RS29305 78da6274d9de8abd0b277eccdce85576 234 Pfam PF00535 Glycosyl transferase family 2 6 159 2.6E-14 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS29305 78da6274d9de8abd0b277eccdce85576 234 Gene3D G3DSA:3.90.550.10 4 205 5.3E-15 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS29305 78da6274d9de8abd0b277eccdce85576 234 SUPERFAMILY SSF53448 4 212 3.13E-24 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 SMART SM00382 42 229 2.8E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 Gene3D G3DSA:3.40.50.300 17 253 1.1E-84 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 Pfam PF00005 ABC transporter 33 181 1.8E-36 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 SUPERFAMILY SSF52540 18 251 5.32E-80 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 PANTHER PTHR24220:SF550 19 258 7.0E-152 T 16-09-2016 Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 PANTHER PTHR24220 19 258 7.0E-152 T 16-09-2016 Spa2297_RS24445 f4638b8dd5211b0e5be4a0959a710a41 258 PIRSF PIRSF039085 14 257 3.0E-112 T 16-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Spa2297_RS18045 f51b3f5225ca7ed0feedc0c5d47917cd 210 Pfam PF01810 LysE type translocator 16 207 5.7E-39 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS18045 f51b3f5225ca7ed0feedc0c5d47917cd 210 PIRSF PIRSF006324 1 209 1.2E-57 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS18045 f51b3f5225ca7ed0feedc0c5d47917cd 210 PANTHER PTHR30086 2 207 7.0E-58 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS18045 f51b3f5225ca7ed0feedc0c5d47917cd 210 PANTHER PTHR30086:SF3 2 207 7.0E-58 T 16-09-2016 Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 Gene3D G3DSA:3.40.50.300 12 225 7.8E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 SMART SM00382 40 226 5.3E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 PANTHER PTHR24220 16 223 1.8E-72 T 16-09-2016 Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 SUPERFAMILY SSF52540 30 228 1.85E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 24 213 1.1E-89 T 16-09-2016 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 PANTHER PTHR24220:SF66 16 223 1.8E-72 T 16-09-2016 Spa2297_RS25035 9fa13ecde5fe4ad703d5ecf1c77bda8c 284 Pfam PF00005 ABC transporter 31 179 2.3E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 SUPERFAMILY SSF82607 5 95 5.49E-28 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 PIRSF PIRSF004555 1 105 3.2E-34 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 PANTHER PTHR33449:SF1 1 104 5.3E-41 T 16-09-2016 Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 PANTHER PTHR33449 1 104 5.3E-41 T 16-09-2016 Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 87 5.1E-23 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 93 20.918 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 Gene3D G3DSA:3.30.1310.10 1 100 6.5E-39 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS17720 583aac3cad2df2bf0b5e9e0315775b18 105 Pfam PF02575 YbaB/EbfC DNA-binding family 6 94 2.3E-32 T 16-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 SUPERFAMILY SSF46689 15 85 6.16E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 PANTHER PTHR30055:SF51 10 209 2.9E-110 T 16-09-2016 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 PANTHER PTHR30055 10 209 2.9E-110 T 16-09-2016 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 Gene3D G3DSA:1.10.357.10 17 191 1.0E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 68 1.9E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS05375 78fdd9cea9279199f306a517d0bb3863 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 Pfam PF13538 UvrD-like helicase C-terminal domain 671 719 5.9E-8 T 16-09-2016 IPR027785 UvrD-like helicase C-terminal domain Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 SUPERFAMILY SSF52540 583 722 2.12E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 SUPERFAMILY SSF52540 483 542 2.12E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 Gene3D G3DSA:3.40.50.300 660 720 7.3E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 Gene3D G3DSA:3.40.50.300 485 613 7.3E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06505 11d3a85e42b429e18a2bd549f9bfdc9e 754 Pfam PF14490 Helix-hairpin-helix containing domain 172 257 5.1E-9 T 16-09-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain Spa2297_RS22865 21e6998856101b1b37dab077f81ff6c2 216 PANTHER PTHR38074:SF1 2 214 8.7E-36 T 16-09-2016 Spa2297_RS22865 21e6998856101b1b37dab077f81ff6c2 216 PANTHER PTHR38074 2 214 8.7E-36 T 16-09-2016 Spa2297_RS22865 21e6998856101b1b37dab077f81ff6c2 216 Pfam PF01987 Mitochondrial biogenesis AIM24 7 211 9.0E-36 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS22865 21e6998856101b1b37dab077f81ff6c2 216 Gene3D G3DSA:3.60.160.10 8 211 4.2E-44 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS22865 21e6998856101b1b37dab077f81ff6c2 216 SUPERFAMILY SSF51219 7 213 5.23E-45 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 Pfam PF01740 STAS domain 17 114 3.3E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 PANTHER PTHR33495 2 122 2.4E-42 T 16-09-2016 Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 SUPERFAMILY SSF52091 16 116 3.34E-24 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 113 1.8E-19 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 Gene3D G3DSA:3.30.750.24 16 119 4.4E-29 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02055 059c972b19c3db673accd85598fb4451 128 PANTHER PTHR33495:SF3 2 122 2.4E-42 T 16-09-2016 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 56 7.5E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 SUPERFAMILY SSF48498 80 193 2.3E-26 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 Pfam PF13977 Bacterial transcriptional repressor 114 192 1.1E-7 T 16-09-2016 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 Gene3D G3DSA:1.10.10.60 3 64 1.3E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 PANTHER PTHR30055:SF89 1 194 2.4E-94 T 16-09-2016 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 Gene3D G3DSA:1.10.357.10 72 194 4.7E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 SUPERFAMILY SSF46689 3 71 1.44E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS10495 a5aa45b2bb5a3261ba148f7971877a34 194 PANTHER PTHR30055 1 194 2.4E-94 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 674 2.1E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 2.1E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 466 2.1E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 678 690 2.1E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 610 2.1E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 226 481 3.2E-41 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 555 736 2.2E-39 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Pfam PF00122 E1-E2 ATPase 224 443 8.1E-63 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF56784 510 755 4.12E-54 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF56784 450 470 4.12E-54 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PANTHER PTHR24093 10 762 7.6E-239 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF81653 262 352 1.83E-23 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF55008 8 74 2.36E-18 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PANTHER PTHR24093:SF50 10 762 7.6E-239 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Gene3D G3DSA:2.70.150.10 215 353 1.9E-26 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00943 Copper-transporting ATPase signature 689 703 1.7E-6 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00943 Copper-transporting ATPase signature 435 450 1.7E-6 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00943 Copper-transporting ATPase signature 632 649 1.7E-6 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00943 Copper-transporting ATPase signature 26 40 1.7E-6 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 PRINTS PR00943 Copper-transporting ATPase signature 375 389 1.7E-6 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF81665 353 446 2.75E-11 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF81665 216 255 2.75E-11 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 SUPERFAMILY SSF81665 704 731 2.75E-11 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 454 460 - T 16-09-2016 IPR018303 P-type ATPase, phosphorylation site Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Pfam PF00403 Heavy-metal-associated domain 14 72 2.3E-14 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 216 758 1.1E-150 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 44 - T 16-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Gene3D G3DSA:3.40.50.1000 581 723 6.0E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Gene3D G3DSA:3.40.50.1000 423 468 6.0E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Pfam PF00702 haloacid dehalogenase-like hydrolase 448 669 6.4E-46 T 16-09-2016 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 170 757 7.6E-178 T 16-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Gene3D G3DSA:3.40.1110.10 469 580 5.3E-23 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS03505 0f43851ae1babdf9d84b376c9fd2038a 764 Gene3D G3DSA:3.30.70.100 8 73 1.4E-22 T 16-09-2016 Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 Pfam PF00106 short chain dehydrogenase 10 197 1.0E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PANTHER PTHR24322 153 178 1.2E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PANTHER PTHR24322 13 137 1.2E-38 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.1E-7 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 6.5E-5 T 16-09-2016 Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.2E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.2E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.2E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.2E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 Gene3D G3DSA:3.40.50.720 7 209 9.2E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13795 cba488af5472203280fa756ff00db5ce 297 SUPERFAMILY SSF51735 4 256 8.28E-59 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 SUPERFAMILY SSF52425 3 181 1.57E-37 T 16-09-2016 IPR006050 DNA photolyase, N-terminal Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Pfam PF00875 DNA photolyase 4 164 1.5E-37 T 16-09-2016 IPR006050 DNA photolyase, N-terminal Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 SUPERFAMILY SSF48173 190 454 3.53E-93 T 16-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 PANTHER PTHR11455 1 454 1.5E-149 T 16-09-2016 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Gene3D G3DSA:3.40.50.620 2 145 1.2E-37 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 312 324 - T 16-09-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Gene3D G3DSA:1.10.579.10 270 451 2.7E-68 T 16-09-2016 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 PRINTS PR00147 DNA photolyase signature 332 350 3.8E-26 T 16-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 PRINTS PR00147 DNA photolyase signature 141 157 3.8E-26 T 16-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 PRINTS PR00147 DNA photolyase signature 371 385 3.8E-26 T 16-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 PRINTS PR00147 DNA photolyase signature 312 328 3.8E-26 T 16-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Gene3D G3DSA:1.25.40.80 195 269 1.2E-29 T 16-09-2016 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Gene3D G3DSA:1.25.40.80 146 162 1.2E-29 T 16-09-2016 Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 332 351 - T 16-09-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Spa2297_RS29485 3766baeb2758e3048037b0e222cc48c8 458 Pfam PF03441 FAD binding domain of DNA photolyase 262 451 1.4E-71 T 16-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 PANTHER PTHR10434 9 262 1.9E-102 T 16-09-2016 Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 SMART SM00563 41 159 2.4E-35 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 SUPERFAMILY SSF69593 5 227 1.7E-40 T 16-09-2016 Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 PANTHER PTHR10434:SF21 9 262 1.9E-102 T 16-09-2016 Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 Gene3D G3DSA:3.40.1130.10 32 221 6.8E-20 T 16-09-2016 Spa2297_RS23575 d2a2f5e1e76189f23bc0c303985d7eba 263 Pfam PF01553 Acyltransferase 30 155 9.6E-21 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 Gene3D G3DSA:3.40.50.2300 90 201 2.5E-32 T 16-09-2016 Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 PANTHER PTHR32196 90 348 8.5E-51 T 16-09-2016 Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 Pfam PF13407 Periplasmic binding protein domain 90 339 6.5E-51 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 Gene3D G3DSA:3.40.50.2300 202 359 3.0E-44 T 16-09-2016 Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 SUPERFAMILY SSF53822 77 359 2.04E-72 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS00280 6df18b3098af76ab07f1f2042707b42b 365 PANTHER PTHR32196:SF9 90 348 8.5E-51 T 16-09-2016 Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 SUPERFAMILY SSF81296 20 118 3.64E-24 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 PANTHER PTHR34820:SF2 1 399 3.5E-154 T 16-09-2016 Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 Pfam PF04234 CopC domain 21 117 2.9E-24 T 16-09-2016 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 Pfam PF05425 Copper resistance protein D 316 394 2.1E-15 T 16-09-2016 IPR008457 Copper resistance protein D GO:0016021 Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 PANTHER PTHR34820 1 399 3.5E-154 T 16-09-2016 Spa2297_RS15885 f0bfa65fabc01c0c823b25b0793c54bb 409 Gene3D G3DSA:2.60.40.1220 20 118 1.3E-27 T 16-09-2016 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 ProSitePatterns PS01270 Band 7 protein family signature. 137 165 - T 16-09-2016 IPR018080 Band 7/stomatin-like, conserved site Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 Pfam PF01145 SPFH domain / Band 7 family 36 197 4.6E-34 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 SUPERFAMILY SSF117892 54 188 2.09E-40 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PANTHER PTHR10264 1 322 9.8E-119 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PRINTS PR00721 Stomatin signature 113 130 4.7E-30 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PRINTS PR00721 Stomatin signature 133 156 4.7E-30 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PRINTS PR00721 Stomatin signature 157 175 4.7E-30 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PRINTS PR00721 Stomatin signature 176 197 4.7E-30 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PRINTS PR00721 Stomatin signature 78 99 4.7E-30 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 PANTHER PTHR10264:SF27 1 322 9.8E-119 T 16-09-2016 Spa2297_RS02530 ce39ef7c617d21d89a1c0e552749e1c9 348 SMART SM00244 23 181 9.5E-53 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 25 538 18.086 T 16-09-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 152 537 7.5E-116 T 16-09-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 PANTHER PTHR22773:SF41 22 127 3.4E-181 T 16-09-2016 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 PANTHER PTHR22773:SF41 146 544 3.4E-181 T 16-09-2016 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 Pfam PF00361 Proton-conducting membrane transporter 179 485 1.5E-72 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 PANTHER PTHR22773 146 544 3.4E-181 T 16-09-2016 Spa2297_RS19260 a0970d23bcfabdc906c8162f9e3f5faf 549 PANTHER PTHR22773 22 127 3.4E-181 T 16-09-2016 Spa2297_RS30395 b3d04536d21559923823ab3b1147a86f 290 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 15 273 3.1E-41 T 16-09-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 Spa2297_RS30395 b3d04536d21559923823ab3b1147a86f 290 PANTHER PTHR36852 2 287 1.8E-121 T 16-09-2016 Spa2297_RS30395 b3d04536d21559923823ab3b1147a86f 290 PANTHER PTHR36852:SF2 2 287 1.8E-121 T 16-09-2016 Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 Gene3D G3DSA:1.10.1040.10 186 292 3.7E-5 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 PIRSF PIRSF000103 2 294 6.1E-38 T 16-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 PANTHER PTHR22981:SF76 8 194 8.6E-32 T 16-09-2016 Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 Gene3D G3DSA:3.40.50.720 9 166 4.3E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 PANTHER PTHR22981 8 194 8.6E-32 T 16-09-2016 Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 SUPERFAMILY SSF51735 10 166 1.06E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS15210 10eb16309b5f002a1eeb10cfed2b306a 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 166 5.9E-20 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS25145 40b918884babde030f6babbe5e0989ae 281 Pfam PF08223 PaaX-like protein C-terminal domain 99 265 1.2E-51 T 16-09-2016 IPR013225 PaaX-like, C-terminal UniPathway: UPA00930 Spa2297_RS25145 40b918884babde030f6babbe5e0989ae 281 PANTHER PTHR30319 1 275 1.4E-85 T 16-09-2016 Spa2297_RS25145 40b918884babde030f6babbe5e0989ae 281 Pfam PF07848 PaaX-like protein 13 81 1.4E-20 T 16-09-2016 IPR012906 PaaX-like, N-terminal UniPathway: UPA00930 Spa2297_RS25145 40b918884babde030f6babbe5e0989ae 281 PIRSF PIRSF020623 1 277 2.0E-90 T 16-09-2016 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UniPathway: UPA00930 Spa2297_RS25145 40b918884babde030f6babbe5e0989ae 281 PANTHER PTHR30319:SF1 1 275 1.4E-85 T 16-09-2016 Spa2297_RS23665 6cf2abe8e60e5804361baa8de0a364e7 93 Gene3D G3DSA:3.30.70.100 5 93 5.4E-26 T 16-09-2016 Spa2297_RS23665 6cf2abe8e60e5804361baa8de0a364e7 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 16-09-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spa2297_RS23665 6cf2abe8e60e5804361baa8de0a364e7 93 Pfam PF00708 Acylphosphatase 6 93 1.2E-20 T 16-09-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spa2297_RS23665 6cf2abe8e60e5804361baa8de0a364e7 93 PANTHER PTHR10029 1 93 8.6E-26 T 16-09-2016 Spa2297_RS23665 6cf2abe8e60e5804361baa8de0a364e7 93 SUPERFAMILY SSF54975 4 93 3.49E-23 T 16-09-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 16-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 SUPERFAMILY SSF53850 7 260 1.53E-53 T 16-09-2016 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 Gene3D G3DSA:3.40.190.10 116 221 7.3E-21 T 16-09-2016 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 PANTHER PTHR18966:SF191 59 261 1.6E-31 T 16-09-2016 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 SMART SM00062 38 262 1.5E-70 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 260 2.6E-47 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 Gene3D G3DSA:3.40.190.10 222 256 1.3E-26 T 16-09-2016 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 Gene3D G3DSA:3.40.190.10 36 115 1.3E-26 T 16-09-2016 Spa2297_RS24440 6e982d75e108eb7909dfe01bebd5c4e1 277 PANTHER PTHR18966 59 261 1.6E-31 T 16-09-2016 Spa2297_RS07295 a848430eb06781f67adf401e3e7cd8f9 267 Pfam PF02104 SURF1 family 20 230 1.3E-34 T 16-09-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Spa2297_RS07295 a848430eb06781f67adf401e3e7cd8f9 267 PANTHER PTHR23427:SF2 11 262 2.3E-34 T 16-09-2016 Spa2297_RS07295 a848430eb06781f67adf401e3e7cd8f9 267 PANTHER PTHR23427 11 262 2.3E-34 T 16-09-2016 Spa2297_RS25645 7f921f4e2e0f9d44e1a5ef1739b34674 482 Gene3D G3DSA:3.80.30.20 58 286 1.0E-25 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS25645 7f921f4e2e0f9d44e1a5ef1739b34674 482 SUPERFAMILY SSF102114 14 437 1.83E-67 T 16-09-2016 Spa2297_RS25645 7f921f4e2e0f9d44e1a5ef1739b34674 482 SMART SM00729 56 279 3.4E-24 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS25645 7f921f4e2e0f9d44e1a5ef1739b34674 482 Pfam PF04055 Radical SAM superfamily 62 237 2.1E-17 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS25645 7f921f4e2e0f9d44e1a5ef1739b34674 482 PANTHER PTHR13932 1 447 3.2E-67 T 16-09-2016 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 Gene3D G3DSA:3.40.50.2000 243 441 8.2E-58 T 16-09-2016 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 PANTHER PTHR10788:SF6 9 440 4.2E-124 T 16-09-2016 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 PANTHER PTHR10788 9 440 4.2E-124 T 16-09-2016 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 SUPERFAMILY SSF53756 10 461 4.63E-108 T 16-09-2016 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 Pfam PF00982 Glycosyltransferase family 20 10 460 5.1E-101 T 16-09-2016 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 Spa2297_RS14830 2a6a47cbd4f6dfd21d3afa48b42e5164 462 Gene3D G3DSA:3.40.50.2000 9 224 1.0E-56 T 16-09-2016 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 SMART SM00530 20 74 7.2E-12 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 Gene3D G3DSA:1.10.260.40 7 75 9.2E-29 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 PANTHER PTHR10245:SF59 1 79 9.9E-30 T 16-09-2016 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 PANTHER PTHR10245 1 79 9.9E-30 T 16-09-2016 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 Pfam PF13560 Helix-turn-helix domain 16 77 2.3E-14 T 16-09-2016 Spa2297_RS26740 06128c837dd0005bb78d6f044a242b68 83 SUPERFAMILY SSF47413 6 76 1.72E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS30355 4ceefab44ceb68c90daa453483bc6fac 637 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 21 371 5.1E-97 T 16-09-2016 IPR016624 Uncharacterised conserved protein UCP014753 Spa2297_RS30355 4ceefab44ceb68c90daa453483bc6fac 637 PIRSF PIRSF014753 2 629 3.5E-150 T 16-09-2016 IPR016624 Uncharacterised conserved protein UCP014753 Spa2297_RS30355 4ceefab44ceb68c90daa453483bc6fac 637 PANTHER PTHR35339:SF1 1 631 1.1E-199 T 16-09-2016 Spa2297_RS30355 4ceefab44ceb68c90daa453483bc6fac 637 PANTHER PTHR35339 1 631 1.1E-199 T 16-09-2016 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.621 T 16-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 PANTHER PTHR12903 1 107 7.5E-45 T 16-09-2016 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 Pfam PF00467 KOW motif 5 36 2.9E-7 T 16-09-2016 IPR005824 KOW Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 Gene3D G3DSA:2.30.30.30 1 95 4.3E-26 T 16-09-2016 IPR014722 Ribosomal protein L2 domain 2 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 SUPERFAMILY SSF50104 1 105 2.03E-30 T 16-09-2016 IPR008991 Translation protein SH3-like domain Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 16-09-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 1.2E-23 T 16-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 SMART SM00739 2 29 2.1E-5 T 16-09-2016 IPR005824 KOW Spa2297_RS19850 adcd8d18b9e31c9369d37603f157297a 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 2.9E-36 T 16-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS03015 3c59607ceaa56bb582789b80795f2d29 199 PANTHER PTHR28629 2 199 7.1E-74 T 16-09-2016 Spa2297_RS03015 3c59607ceaa56bb582789b80795f2d29 199 SMART SM01120 31 195 4.1E-73 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS03015 3c59607ceaa56bb582789b80795f2d29 199 Pfam PF02734 DAK2 domain 31 194 9.6E-52 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS03015 3c59607ceaa56bb582789b80795f2d29 199 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 8 194 2.7E-70 T 16-09-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00563+2.7.-.- Spa2297_RS03015 3c59607ceaa56bb582789b80795f2d29 199 SUPERFAMILY SSF101473 2 195 1.57E-55 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 157 321 1.1E-56 T 16-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 Gene3D G3DSA:3.20.20.70 178 312 3.8E-57 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 PANTHER PTHR32179 30 325 9.2E-118 T 16-09-2016 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 PIRSF PIRSF006250 49 325 7.1E-95 T 16-09-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 66 155 3.8E-24 T 16-09-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 59 321 4.2E-92 T 16-09-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 SUPERFAMILY SSF54675 49 156 1.61E-26 T 16-09-2016 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 Gene3D G3DSA:3.90.1170.20 47 177 6.8E-45 T 16-09-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Spa2297_RS18295 524dc320aef1ced640742ff5ef7e558d 326 SUPERFAMILY SSF51690 157 322 6.67E-58 T 16-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 Gene3D G3DSA:3.40.1080.10 3 232 1.0E-97 T 16-09-2016 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 140 7.5E-40 T 16-09-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 SUPERFAMILY SSF100950 2 237 1.19E-83 T 16-09-2016 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 PANTHER PTHR13707 1 250 3.7E-126 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 16-09-2016 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 SMART SM00882 5 234 5.5E-81 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS27895 38fb666b6e50bbd2ea1252e08b201cbc 251 Pfam PF01144 Coenzyme A transferase 6 233 3.6E-71 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS26350 a65c068b7456f1c6665fce432d63b4ba 140 PANTHER PTHR31793 2 133 2.1E-29 T 16-09-2016 Spa2297_RS26350 a65c068b7456f1c6665fce432d63b4ba 140 Pfam PF13279 Thioesterase-like superfamily 14 120 7.4E-15 T 16-09-2016 Spa2297_RS26350 a65c068b7456f1c6665fce432d63b4ba 140 Gene3D G3DSA:3.10.129.10 2 130 1.0E-33 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS26350 a65c068b7456f1c6665fce432d63b4ba 140 SUPERFAMILY SSF54637 3 131 2.89E-34 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 PANTHER PTHR10803 9 304 4.1E-59 T 16-09-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 SUPERFAMILY SSF52540 30 203 2.85E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 SUPERFAMILY SSF52540 245 306 2.85E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 Pfam PF02374 Anion-transporting ATPase 33 304 1.8E-26 T 16-09-2016 IPR025723 Anion-transporting ATPase-like domain Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 Gene3D G3DSA:3.40.50.300 29 191 1.5E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17835 44dd77a87db1700f3d0bd0ca3b131cf8 475 Gene3D G3DSA:3.40.50.300 232 312 1.5E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00412 Epoxide hydrolase signature 99 112 4.8E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00412 Epoxide hydrolase signature 34 52 4.8E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00412 Epoxide hydrolase signature 260 282 4.8E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00412 Epoxide hydrolase signature 113 126 4.8E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PANTHER PTHR10992:SF870 5 285 2.6E-107 T 16-09-2016 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 SUPERFAMILY SSF53474 5 285 4.59E-68 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 Gene3D G3DSA:3.40.50.1820 3 286 8.8E-64 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 4.6E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 4.6E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 Pfam PF00561 alpha/beta hydrolase fold 28 268 1.7E-22 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS00825 5efc2779045abea3f0bcf443bca8886c 290 PANTHER PTHR10992 5 285 2.6E-107 T 16-09-2016 Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 PANTHER PTHR24421 95 110 4.6E-24 T 16-09-2016 Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 PANTHER PTHR24421 235 430 4.6E-24 T 16-09-2016 Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 PANTHER PTHR24421:SF1 95 110 4.6E-24 T 16-09-2016 Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 SUPERFAMILY SSF55874 313 422 2.62E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 Gene3D G3DSA:3.30.565.10 299 425 2.5E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 PANTHER PTHR24421:SF1 235 430 4.6E-24 T 16-09-2016 Spa2297_RS20215 42ee80e56a1628530ea218a5182eea16 430 Pfam PF04024 PspC domain 16 71 2.3E-14 T 16-09-2016 IPR007168 Phage shock protein, PspC, N-terminal Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 Gene3D G3DSA:3.40.710.10 245 538 2.5E-50 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 54 160 2.0E-5 T 16-09-2016 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 PANTHER PTHR30627:SF4 195 539 1.6E-159 T 16-09-2016 Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 537 6.3E-33 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 SUPERFAMILY SSF56601 239 538 8.26E-52 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13730 b12460407f469b367565345022ba44b7 541 PANTHER PTHR30627 195 539 1.6E-159 T 16-09-2016 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 SUPERFAMILY SSF53167 17 274 1.1E-79 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 PANTHER PTHR11904:SF9 9 274 3.8E-100 T 16-09-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 35 271 1.0E-104 T 16-09-2016 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 PIRSF PIRSF000477 9 274 1.1E-88 T 16-09-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 Gene3D G3DSA:3.40.50.1580 14 273 8.1E-90 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 35 271 2.2E-76 T 16-09-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 Pfam PF01048 Phosphorylase superfamily 36 271 4.0E-42 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS20815 b5d7427e2799b2aa0ee6b5b188b84196 274 PANTHER PTHR11904 9 274 3.8E-100 T 16-09-2016 IPR001369 PNP/MTAP phosphorylase Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 Gene3D G3DSA:3.40.630.30 1 199 8.1E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 PANTHER PTHR21471 1 200 1.1E-43 T 16-09-2016 Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 PANTHER PTHR21471:SF63 1 200 1.1E-43 T 16-09-2016 Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 SUPERFAMILY SSF55729 114 198 5.75E-21 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 SUPERFAMILY SSF55729 1 66 5.75E-21 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22225 c3faa94fe56af50d83a62165675ebf7c 206 Pfam PF00583 Acetyltransferase (GNAT) family 119 177 4.9E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 Gene3D G3DSA:1.10.10.10 114 178 3.5E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 Pfam PF08281 Sigma-70, region 4 119 172 3.4E-14 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 Pfam PF04542 Sigma-70 region 2 27 88 2.2E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 SUPERFAMILY SSF88946 4 94 6.91E-22 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 PANTHER PTHR30173:SF16 4 176 6.9E-81 T 16-09-2016 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 PANTHER PTHR30173 4 176 6.9E-81 T 16-09-2016 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 Gene3D G3DSA:1.10.1740.10 3 109 9.4E-23 T 16-09-2016 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 SUPERFAMILY SSF88659 112 177 6.76E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS06760 bbb3b822372ac5ccad3cbdd54e8a20fa 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 176 1.8E-24 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21470 623d084abe9e053d8410ddfefba8e657 208 PANTHER PTHR10108 27 158 4.2E-20 T 16-09-2016 Spa2297_RS21470 623d084abe9e053d8410ddfefba8e657 208 SUPERFAMILY SSF53335 5 151 2.13E-31 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21470 623d084abe9e053d8410ddfefba8e657 208 Pfam PF13649 Methyltransferase domain 42 135 9.4E-16 T 16-09-2016 Spa2297_RS21470 623d084abe9e053d8410ddfefba8e657 208 Gene3D G3DSA:3.40.50.150 24 205 1.2E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00780 f04e7f2137d63d985140d6a5162ebf63 415 Pfam PF05834 Lycopene cyclase protein 11 394 2.9E-107 T 16-09-2016 Spa2297_RS00780 f04e7f2137d63d985140d6a5162ebf63 415 SUPERFAMILY SSF51905 6 185 2.64E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00780 f04e7f2137d63d985140d6a5162ebf63 415 SUPERFAMILY SSF51905 271 364 2.64E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00780 f04e7f2137d63d985140d6a5162ebf63 415 Gene3D G3DSA:3.50.50.60 273 316 4.1E-14 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00780 f04e7f2137d63d985140d6a5162ebf63 415 Gene3D G3DSA:3.50.50.60 6 176 4.1E-14 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 264 278 1.5E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 278 294 1.5E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 294 306 1.5E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 Pfam PF00196 Bacterial regulatory proteins, luxR family 265 314 3.9E-9 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 SUPERFAMILY SSF46894 254 323 3.4E-13 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 SMART SM00421 261 318 5.9E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17510 b12068aa1449593b1cfcd16632267258 345 Gene3D G3DSA:1.10.10.10 257 323 1.3E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 425 6.4E-160 T 16-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 Gene3D G3DSA:1.20.5.570 450 485 1.8E-4 T 16-09-2016 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 442 1.8E-196 T 16-09-2016 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 450 1.2E-138 T 16-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 Gene3D G3DSA:3.40.1670.10 334 449 2.1E-38 T 16-09-2016 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 SUPERFAMILY SSF143968 320 485 7.06E-55 T 16-09-2016 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 PANTHER PTHR30108 1 485 1.6E-224 T 16-09-2016 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 PANTHER PTHR30108:SF1 1 485 1.6E-224 T 16-09-2016 Spa2297_RS18840 45d6db54926621bb821bdc6988d614d8 485 SUPERFAMILY SSF50475 3 319 2.94E-114 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 Gene3D G3DSA:3.40.50.2300 173 305 6.3E-16 T 16-09-2016 Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 PANTHER PTHR30036:SF2 8 337 9.1E-120 T 16-09-2016 Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 SUPERFAMILY SSF53822 54 326 2.36E-47 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 Gene3D G3DSA:3.40.50.2300 50 172 1.0E-28 T 16-09-2016 Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 PANTHER PTHR30036 8 337 9.1E-120 T 16-09-2016 Spa2297_RS25595 d9adff195e3988151d74ea330718f7d3 337 Pfam PF13407 Periplasmic binding protein domain 57 299 1.0E-35 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS30000 f6ef420bc6e13e6144b10eb035748a72 121 SUPERFAMILY SSF54427 23 116 8.03E-13 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS30000 f6ef420bc6e13e6144b10eb035748a72 121 Gene3D G3DSA:3.10.450.50 26 115 4.6E-9 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS30000 f6ef420bc6e13e6144b10eb035748a72 121 Pfam PF12680 SnoaL-like domain 18 112 3.1E-10 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 PANTHER PTHR33169 1 187 6.0E-67 T 16-09-2016 Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 7.7E-11 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 Pfam PF10400 Virulence activator alpha C-term 92 174 2.4E-22 T 16-09-2016 IPR018309 Transcription regulator PadR, C-terminal Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 SUPERFAMILY SSF46785 2 176 1.15E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 PANTHER PTHR33169:SF4 1 187 6.0E-67 T 16-09-2016 Spa2297_RS03040 1821fea21d6862a2fc118c2f658f72f3 187 Gene3D G3DSA:1.10.10.10 1 87 4.5E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 Gene3D G3DSA:3.30.9.10 181 346 3.5E-52 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 Pfam PF01494 FAD binding domain 13 326 7.5E-14 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 PANTHER PTHR10617 8 413 1.8E-110 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.5E-10 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 3.5E-10 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 3.5E-10 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 Gene3D G3DSA:3.50.50.60 10 180 4.3E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 PANTHER PTHR10617:SF101 8 413 1.8E-110 T 16-09-2016 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 14 336 9.5E-91 T 16-09-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 SUPERFAMILY SSF51905 11 195 6.28E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS19180 e42a96036a2b84677266e82ff1b7216d 430 SUPERFAMILY SSF51905 291 383 6.28E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 2.0E-30 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 PANTHER PTHR10438:SF266 5 129 2.7E-45 T 16-09-2016 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 PRINTS PR00421 Thioredoxin family signature 30 39 5.8E-8 T 16-09-2016 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 PRINTS PR00421 Thioredoxin family signature 69 80 5.8E-8 T 16-09-2016 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 PRINTS PR00421 Thioredoxin family signature 22 30 5.8E-8 T 16-09-2016 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 SUPERFAMILY SSF52833 4 104 4.86E-34 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 Gene3D G3DSA:3.40.30.10 3 103 3.8E-33 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 Pfam PF00085 Thioredoxin 4 101 1.8E-28 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS29170 d47afb17d6733190e440c044167e98ec 129 PANTHER PTHR10438 5 129 2.7E-45 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 SUPERFAMILY SSF53681 106 221 1.48E-18 T 16-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 SUPERFAMILY SSF53681 2 102 3.73E-20 T 16-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 16-09-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 PANTHER PTHR21198:SF2 2 260 1.3E-68 T 16-09-2016 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 PANTHER PTHR21198 2 260 1.3E-68 T 16-09-2016 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 42 193 1.5E-11 T 16-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS03380 3558509b6330448db68cc0f51c44b2c2 261 Gene3D G3DSA:3.40.50.1860 2 154 2.9E-32 T 16-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS25970 fe834f8f7a536169d0f5d44768472910 158 SUPERFAMILY SSF109854 96 145 1.16E-5 T 16-09-2016 Spa2297_RS25970 fe834f8f7a536169d0f5d44768472910 158 Gene3D G3DSA:1.20.120.450 96 145 1.4E-4 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 PANTHER PTHR11732 1 347 1.3E-141 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 PRINTS PR00069 Aldo-keto reductase signature 48 72 1.7E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.7E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.7E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 Gene3D G3DSA:3.20.20.100 1 321 3.2E-92 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 Pfam PF00248 Aldo/keto reductase family 16 318 2.8E-67 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 PANTHER PTHR11732:SF185 1 347 1.3E-141 T 16-09-2016 Spa2297_RS30870 d357d68bff3998a7a74483c3f1b90bcb 357 SUPERFAMILY SSF51430 2 320 6.55E-96 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 PANTHER PTHR30204:SF0 3 161 2.2E-78 T 16-09-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 Gene3D G3DSA:1.10.1660.10 65 142 7.0E-18 T 16-09-2016 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 SUPERFAMILY SSF46955 11 131 2.31E-27 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 Pfam PF00376 MerR family regulatory protein 12 48 4.8E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 9.5E-14 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 9.5E-14 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 9.5E-14 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 PANTHER PTHR30204 3 161 2.2E-78 T 16-09-2016 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 SMART SM00422 11 79 1.9E-24 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 150 1.1E-73 T 16-09-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 Pfam PF09278 MerR, DNA binding 53 118 6.2E-19 T 16-09-2016 IPR015358 Transcription regulator MerR, DNA binding Spa2297_RS06645 dd080c0e9124b233313b6d30abeb51fd 169 Gene3D G3DSA:1.10.1660.10 11 64 2.3E-19 T 16-09-2016 Spa2297_RS29700 fc654ce7199573c5f5dae58b5778c8b0 276 PANTHER PTHR14136 11 243 6.2E-54 T 16-09-2016 Spa2297_RS29700 fc654ce7199573c5f5dae58b5778c8b0 276 Pfam PF00805 Pentapeptide repeats (8 copies) 188 225 3.7E-13 T 16-09-2016 IPR001646 Pentapeptide repeat Spa2297_RS29700 fc654ce7199573c5f5dae58b5778c8b0 276 PANTHER PTHR14136:SF0 11 243 6.2E-54 T 16-09-2016 Spa2297_RS29700 fc654ce7199573c5f5dae58b5778c8b0 276 SUPERFAMILY SSF141571 55 91 2.49E-23 T 16-09-2016 Spa2297_RS29700 fc654ce7199573c5f5dae58b5778c8b0 276 SUPERFAMILY SSF141571 163 254 2.49E-23 T 16-09-2016 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 SUPERFAMILY SSF51366 4 213 8.24E-63 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 16-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 PIRSF PIRSF001461 1 224 2.7E-96 T 16-09-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 PANTHER PTHR11749:SF3 1 228 1.1E-121 T 16-09-2016 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 212 8.6E-81 T 16-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 Gene3D G3DSA:3.20.20.70 3 218 1.3E-91 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 PANTHER PTHR11749 1 228 1.1E-121 T 16-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 199 3.7E-78 T 16-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS05525 86fc4a825291e97ad123ae37bf1003ed 228 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 16-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 SUPERFAMILY SSF52540 26 265 1.38E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 Pfam PF00005 ABC transporter 44 189 2.0E-35 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 PANTHER PTHR24220:SF350 385 401 6.2E-166 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 PANTHER PTHR24220 385 401 6.2E-166 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 PANTHER PTHR24220 27 302 6.2E-166 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 SMART SM00382 52 248 1.3E-20 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 PANTHER PTHR24220:SF350 27 302 6.2E-166 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 SUPERFAMILY SSF54631 276 395 7.94E-12 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 Gene3D G3DSA:3.40.50.300 23 262 7.2E-78 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 Gene3D G3DSA:3.10.580.10 276 388 2.8E-10 T 16-09-2016 Spa2297_RS12545 afa4a4e7e6bd43d77c231784d9f3c132 428 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 42 390 1.8E-104 T 16-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 SMART SM00418 4 89 1.2E-16 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 SUPERFAMILY SSF46785 4 84 1.48E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 Pfam PF12840 Helix-turn-helix domain 3 69 6.9E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 Gene3D G3DSA:1.10.10.10 3 88 2.6E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 PANTHER PTHR33154 1 84 2.4E-17 T 16-09-2016 Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 4.5E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS31170 f687bd1887907164a4b12b0c650ef298 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 4.5E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 PANTHER PTHR28004:SF1 21 431 5.7E-186 T 16-09-2016 Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 Gene3D G3DSA:3.20.20.10 145 270 4.8E-11 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 PANTHER PTHR28004 21 431 5.7E-186 T 16-09-2016 Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 SMART SM01119 320 418 1.7E-32 T 16-09-2016 IPR026956 D-serine dehydratase-like domain Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 Pfam PF14031 Putative serine dehydratase domain 320 416 8.9E-15 T 16-09-2016 IPR026956 D-serine dehydratase-like domain Spa2297_RS21110 fb5f9435ab79198742e925c9f8ffccb6 431 SUPERFAMILY SSF51419 58 275 7.85E-23 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 Pfam PF01168 Alanine racemase, N-terminal domain 18 244 1.0E-62 T 16-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 TIGRFAM TIGR00492 alr: alanine racemase 14 386 1.4E-90 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PANTHER PTHR30511:SF0 8 388 9.8E-145 T 16-09-2016 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 Gene3D G3DSA:3.20.20.10 20 237 8.7E-67 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 SMART SM01005 259 386 2.9E-66 T 16-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 Hamap MF_01201 Alanine racemase. 11 386 32.382 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 Pfam PF00842 Alanine racemase, C-terminal domain 259 385 4.1E-39 T 16-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PANTHER PTHR30511 8 388 9.8E-145 T 16-09-2016 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 SUPERFAMILY SSF50621 252 387 1.33E-47 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 16-09-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 Gene3D G3DSA:2.40.37.10 238 387 2.4E-59 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 292 307 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 36 52 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 275 290 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 313 330 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 368 381 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 217 244 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 136 148 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 PRINTS PR00992 Alanine racemase signature 174 185 4.1E-57 T 16-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS20005 985846151bcd4382968cb8b97f4986fb 388 SUPERFAMILY SSF51419 18 260 1.28E-59 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS07300 b5e347c7faf7c1fb3041eb47f67f7033 595 Gene3D G3DSA:1.50.10.10 213 588 8.4E-84 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS07300 b5e347c7faf7c1fb3041eb47f67f7033 595 SUPERFAMILY SSF48208 197 588 2.95E-105 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS07300 b5e347c7faf7c1fb3041eb47f67f7033 595 PANTHER PTHR31616 5 588 1.5E-200 T 16-09-2016 Spa2297_RS07300 b5e347c7faf7c1fb3041eb47f67f7033 595 PANTHER PTHR31616:SF0 5 588 1.5E-200 T 16-09-2016 Spa2297_RS07300 b5e347c7faf7c1fb3041eb47f67f7033 595 Pfam PF00723 Glycosyl hydrolases family 15 217 585 1.3E-75 T 16-09-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 Spa2297_RS29090 89fd5e4c4f4b01623b9689ec8a4cf455 275 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 8 263 1.1E-103 T 16-09-2016 IPR012664 Conserved hypothetical protein CHP02452 Spa2297_RS29090 89fd5e4c4f4b01623b9689ec8a4cf455 275 PIRSF PIRSF014899 1 271 2.3E-125 T 16-09-2016 IPR012664 Conserved hypothetical protein CHP02452 Spa2297_RS29090 89fd5e4c4f4b01623b9689ec8a4cf455 275 PANTHER PTHR35596 8 275 9.5E-70 T 16-09-2016 Spa2297_RS29090 89fd5e4c4f4b01623b9689ec8a4cf455 275 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 9 149 1.7E-49 T 16-09-2016 IPR019261 Domain of unknown function DUF2263 Spa2297_RS02835 19f5e638daedcb06524255b8a5ee830d 284 Gene3D G3DSA:3.40.50.150 41 213 2.7E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02835 19f5e638daedcb06524255b8a5ee830d 284 PANTHER PTHR10108 41 212 6.2E-19 T 16-09-2016 Spa2297_RS02835 19f5e638daedcb06524255b8a5ee830d 284 Pfam PF13649 Methyltransferase domain 56 154 6.6E-15 T 16-09-2016 Spa2297_RS02835 19f5e638daedcb06524255b8a5ee830d 284 SUPERFAMILY SSF53335 30 216 8.13E-33 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 2.8E-116 T 16-09-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 PANTHER PTHR11669:SF0 1 374 9.0E-153 T 16-09-2016 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 238 364 5.3E-14 T 16-09-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 SUPERFAMILY SSF52540 32 222 1.8E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 Gene3D G3DSA:1.10.8.60 168 245 4.1E-20 T 16-09-2016 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 Gene3D G3DSA:3.40.50.300 15 167 6.7E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 SUPERFAMILY SSF48019 247 365 2.38E-22 T 16-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 PANTHER PTHR11669 1 374 9.0E-153 T 16-09-2016 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 Gene3D G3DSA:1.20.272.10 246 364 6.9E-15 T 16-09-2016 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 Pfam PF13177 DNA polymerase III, delta subunit 21 178 7.5E-38 T 16-09-2016 Spa2297_RS15865 2f3c9a4613d02a82c334f78c9147c14f 784 SMART SM00382 37 181 1.7E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS09555 c83823de70b6c869aca1a24cf0d61158 180 PANTHER PTHR33452 5 158 3.4E-41 T 16-09-2016 Spa2297_RS09555 c83823de70b6c869aca1a24cf0d61158 180 PANTHER PTHR33452:SF1 5 158 3.4E-41 T 16-09-2016 Spa2297_RS09555 c83823de70b6c869aca1a24cf0d61158 180 Pfam PF07681 DoxX 10 95 3.6E-13 T 16-09-2016 IPR032808 DoxX family Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 75 220 2.1E-32 T 16-09-2016 Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 PANTHER PTHR11579 78 322 1.6E-123 T 16-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 Gene3D G3DSA:3.40.50.150 29 247 2.8E-67 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 PANTHER PTHR11579:SF0 5 54 1.6E-123 T 16-09-2016 Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 PANTHER PTHR11579:SF0 78 322 1.6E-123 T 16-09-2016 Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 SUPERFAMILY SSF53335 29 211 1.15E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 171 186 - T 16-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Spa2297_RS11320 c2346e33a214643696bb604ac1269f57 324 PANTHER PTHR11579 5 54 1.6E-123 T 16-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 128 401 58.906 T 16-09-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 Pfam PF00448 SRP54-type protein, GTPase domain 204 400 1.7E-72 T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 SMART SM00962 202 401 9.7E-104 T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 PANTHER PTHR11564:SF16 95 402 4.1E-121 T 16-09-2016 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 Gene3D G3DSA:1.20.120.140 130 211 3.3E-27 T 16-09-2016 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 SMART SM00963 105 185 6.4E-25 T 16-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 129 399 4.5E-103 T 16-09-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 SUPERFAMILY SSF52540 151 397 1.15E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 374 387 - T 16-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 SMART SM00382 201 351 3.2E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 PANTHER PTHR11564 95 402 4.1E-121 T 16-09-2016 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 Pfam PF02881 SRP54-type protein, helical bundle domain 116 181 2.7E-13 T 16-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 Spa2297_RS23695 42c18b9455817d0bfadbd68e043518d0 402 Gene3D G3DSA:3.40.50.300 212 401 2.8E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18620 56393cc1fe8de8ee1f787ec48af56af5 446 Pfam PF13560 Helix-turn-helix domain 5 68 1.6E-13 T 16-09-2016 Spa2297_RS18620 56393cc1fe8de8ee1f787ec48af56af5 446 SUPERFAMILY SSF47413 9 72 4.64E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18620 56393cc1fe8de8ee1f787ec48af56af5 446 SMART SM00530 9 65 1.4E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS18620 56393cc1fe8de8ee1f787ec48af56af5 446 Gene3D G3DSA:1.10.260.40 5 67 5.6E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 PANTHER PTHR33495 1 114 4.7E-32 T 16-09-2016 Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 SUPERFAMILY SSF52091 13 116 2.16E-22 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 Gene3D G3DSA:3.30.750.24 12 116 5.1E-24 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 114 3.3E-26 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 Pfam PF01740 STAS domain 14 113 1.2E-15 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29800 c7589052072c1bf54fbc564a7a7d886b 128 PANTHER PTHR33495:SF2 1 114 4.7E-32 T 16-09-2016 Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 SUPERFAMILY SSF50891 175 283 1.06E-13 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 PANTHER PTHR18866 150 263 5.4E-26 T 16-09-2016 Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 SMART SM00797 26 284 1.5E-92 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 PANTHER PTHR18866:SF105 150 263 5.4E-26 T 16-09-2016 Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 Pfam PF02626 Allophanate hydrolase subunit 2 27 283 6.3E-84 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 7 283 1.3E-75 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS31275 9caa0152b54aea781396878a9648fa27 285 Gene3D G3DSA:2.40.100.10 175 283 1.8E-9 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS03235 7c7d86ec3c12666e29cfa9cd8d0f4487 441 Pfam PF08811 Protein of unknown function (DUF1800) 12 438 4.7E-91 T 16-09-2016 IPR014917 Protein of unknown function DUF1800 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 SUPERFAMILY SSF55031 170 271 6.43E-20 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 Gene3D G3DSA:3.40.630.10 12 170 2.2E-45 T 16-09-2016 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 Gene3D G3DSA:3.40.630.10 280 356 2.2E-45 T 16-09-2016 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 Gene3D G3DSA:3.30.70.360 171 270 1.1E-22 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 PANTHER PTHR11014 14 344 5.6E-58 T 16-09-2016 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 Pfam PF07687 Peptidase dimerisation domain 170 268 1.5E-14 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 10 358 3.5E-159 T 16-09-2016 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 SUPERFAMILY SSF53187 279 358 1.53E-42 T 16-09-2016 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 SUPERFAMILY SSF53187 14 182 1.53E-42 T 16-09-2016 Spa2297_RS21665 09bff5c37b8de6fb621f0c785d5af495 359 Pfam PF01546 Peptidase family M20/M25/M40 68 354 6.0E-23 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 PANTHER PTHR26402:SF506 44 234 6.9E-76 T 16-09-2016 Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 Gene3D G3DSA:1.10.10.10 124 221 2.1E-36 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 SMART SM00862 145 219 2.2E-30 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.2E-28 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 SUPERFAMILY SSF46894 126 220 3.59E-30 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS15390 086f73595d4255700e6c880e39721fc0 268 PANTHER PTHR26402 44 234 6.9E-76 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Gene3D G3DSA:1.25.40.10 828 1101 9.1E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Gene3D G3DSA:1.25.40.10 598 751 8.9E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 SUPERFAMILY SSF48452 636 762 4.25E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1119 1133 6.0E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1149 1161 6.0E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1133 1149 6.0E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Pfam PF13191 AAA ATPase domain 5 147 5.9E-14 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 SUPERFAMILY SSF46894 1116 1171 3.74E-14 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PANTHER PTHR26402 1098 1181 7.6E-21 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PANTHER PTHR26402:SF474 1098 1181 7.6E-21 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PANTHER PTHR26402:SF474 589 611 7.6E-21 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Gene3D G3DSA:1.10.10.10 1117 1170 2.9E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Gene3D G3DSA:3.40.50.300 27 155 9.0E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1133 1160 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 PANTHER PTHR26402 589 611 7.6E-21 T 16-09-2016 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 Pfam PF00196 Bacterial regulatory proteins, luxR family 1118 1169 7.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 SMART SM00421 1116 1173 1.1E-17 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14945 d7f88428adbc28610839f08b1afbc15b 1186 SUPERFAMILY SSF52540 21 172 8.75E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 PANTHER PTHR10578 7 370 1.8E-141 T 16-09-2016 Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 SUPERFAMILY SSF51395 12 364 2.93E-92 T 16-09-2016 Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 265 271 - T 16-09-2016 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 PIRSF PIRSF000138 3 372 1.0E-126 T 16-09-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 Pfam PF01070 FMN-dependent dehydrogenase 22 367 6.6E-129 T 16-09-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 Spa2297_RS02910 02e0bea1f308cb88816f408c726bac1d 382 Gene3D G3DSA:3.20.20.70 12 370 1.4E-132 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS00845 60e0684df8186b2ee32588bef4feb4b3 204 Pfam PF01872 RibD C-terminal domain 4 195 3.5E-15 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS00845 60e0684df8186b2ee32588bef4feb4b3 204 PANTHER PTHR38011 2 204 1.4E-82 T 16-09-2016 Spa2297_RS00845 60e0684df8186b2ee32588bef4feb4b3 204 SUPERFAMILY SSF53597 4 201 2.75E-21 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS00845 60e0684df8186b2ee32588bef4feb4b3 204 PANTHER PTHR38011:SF1 2 204 1.4E-82 T 16-09-2016 Spa2297_RS00845 60e0684df8186b2ee32588bef4feb4b3 204 Gene3D G3DSA:3.40.430.10 3 203 2.2E-26 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS13205 c83f7158efffc63967924ab9a6fa39f2 458 PANTHER PTHR33392 1 447 2.9E-150 T 16-09-2016 Spa2297_RS13205 c83f7158efffc63967924ab9a6fa39f2 458 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 79 232 4.9E-45 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13205 c83f7158efffc63967924ab9a6fa39f2 458 PANTHER PTHR33392:SF6 1 447 2.9E-150 T 16-09-2016 Spa2297_RS13205 c83f7158efffc63967924ab9a6fa39f2 458 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 233 2.6E-44 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13205 c83f7158efffc63967924ab9a6fa39f2 458 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 343 429 3.0E-14 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 SUPERFAMILY SSF48317 5 197 6.41E-40 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 Gene3D G3DSA:3.40.50.10330 252 315 4.1E-4 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 Pfam PF01569 PAP2 superfamily 82 192 1.9E-18 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 SUPERFAMILY SSF111331 215 493 1.66E-46 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 Pfam PF00781 Diacylglycerol kinase catalytic domain 230 324 3.4E-15 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 SMART SM00014 77 186 2.2E-21 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 Gene3D G3DSA:1.20.144.10 7 194 3.0E-33 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 SMART SM00046 213 325 8.0E-5 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 PANTHER PTHR14969 1 424 6.2E-129 T 16-09-2016 Spa2297_RS27115 29f1e4316e936f5df20eb2c68af6a65b 514 PANTHER PTHR14969:SF23 1 424 6.2E-129 T 16-09-2016 Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 Gene3D G3DSA:3.40.50.2020 3 184 3.6E-82 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 PANTHER PTHR22573:SF56 11 184 2.4E-85 T 16-09-2016 Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 15 179 4.1E-66 T 16-09-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 Pfam PF00156 Phosphoribosyl transferase domain 22 166 9.2E-25 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 SUPERFAMILY SSF53271 7 184 2.75E-56 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS18175 bb20d7cfadde125f0bec44a72aa95842 186 PANTHER PTHR22573 11 184 2.4E-85 T 16-09-2016 Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 Gene3D G3DSA:3.10.180.10 138 256 3.8E-34 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 Gene3D G3DSA:3.10.180.10 11 123 6.3E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 141 252 2.6E-6 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 PANTHER PTHR33993 1 260 7.2E-104 T 16-09-2016 Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 SUPERFAMILY SSF54593 138 254 6.98E-22 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 PANTHER PTHR33993:SF3 1 260 7.2E-104 T 16-09-2016 Spa2297_RS27945 edaeaa8c8dd865c8f8e3b7ebaca84e65 261 SUPERFAMILY SSF54593 11 164 4.63E-15 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00720 9cd7f063d3a5a177cbab42bf4ee9f313 317 PANTHER PTHR30193 4 316 8.4E-107 T 16-09-2016 Spa2297_RS00720 9cd7f063d3a5a177cbab42bf4ee9f313 317 Gene3D G3DSA:1.10.3720.10 24 307 8.5E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00720 9cd7f063d3a5a177cbab42bf4ee9f313 317 PANTHER PTHR30193:SF6 4 316 8.4E-107 T 16-09-2016 Spa2297_RS00720 9cd7f063d3a5a177cbab42bf4ee9f313 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 313 7.1E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00720 9cd7f063d3a5a177cbab42bf4ee9f313 317 SUPERFAMILY SSF161098 72 304 2.88E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 SUPERFAMILY SSF55797 175 298 6.98E-10 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Pfam PF00188 Cysteine-rich secretory protein family 182 296 3.5E-8 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Pfam PF00188 Cysteine-rich secretory protein family 316 431 4.0E-23 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 PANTHER PTHR32097:SF4 1 430 4.0E-111 T 16-09-2016 Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Gene3D G3DSA:2.60.60.30 25 151 2.2E-16 T 16-09-2016 Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 SUPERFAMILY SSF55797 309 432 4.53E-26 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 PANTHER PTHR32097 1 430 4.0E-111 T 16-09-2016 Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Gene3D G3DSA:3.40.33.10 309 431 8.6E-15 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Gene3D G3DSA:3.40.33.10 172 262 1.7E-4 T 16-09-2016 IPR014044 CAP domain Spa2297_RS02215 4612699a16d79d41fdda26c2fed75251 433 Pfam PF02342 TerD domain 25 153 7.4E-19 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS24545 df086b4c6363c60a4dabed2c7e20e045 408 Gene3D G3DSA:2.40.10.10 172 275 1.1E-6 T 16-09-2016 Spa2297_RS24545 df086b4c6363c60a4dabed2c7e20e045 408 SUPERFAMILY SSF50494 152 368 6.75E-14 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS05850 8edcede32c63e71dcba6cccaa607b748 150 Pfam PF09656 Putative transmembrane protein (PGPGW) 48 100 1.5E-22 T 16-09-2016 IPR019099 Uncharacterised protein family PGPGW, transmembrane Spa2297_RS05850 8edcede32c63e71dcba6cccaa607b748 150 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 26 144 5.8E-44 T 16-09-2016 IPR013434 Conserved hypothetical protein CHP02611 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Pfam PF04545 Sigma-70, region 4 208 256 1.4E-17 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Gene3D G3DSA:1.10.10.10 200 257 3.8E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 SUPERFAMILY SSF88946 31 110 1.31E-26 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 PANTHER PTHR30385 11 261 1.3E-104 T 16-09-2016 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Gene3D G3DSA:1.10.601.10 33 107 3.1E-19 T 16-09-2016 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Pfam PF04542 Sigma-70 region 2 41 109 1.1E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 257 1.8E-31 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 PANTHER PTHR30385:SF4 11 261 1.3E-104 T 16-09-2016 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 PRINTS PR00046 Major sigma-70 factor signature 211 223 1.7E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 PRINTS PR00046 Major sigma-70 factor signature 228 243 1.7E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 PRINTS PR00046 Major sigma-70 factor signature 64 77 1.7E-6 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Gene3D G3DSA:1.10.10.10 109 163 1.9E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 SUPERFAMILY SSF88659 180 258 5.98E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 34 258 5.5E-88 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 SUPERFAMILY SSF88659 113 189 2.57E-12 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS27165 331b0946b2fc4c251e28e46ec3634014 264 Pfam PF04539 Sigma-70 region 3 119 173 3.6E-8 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.515 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 PANTHER PTHR30454 1 375 2.6E-207 T 16-09-2016 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 Pfam PF04551 GcpE protein 22 361 4.7E-135 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 SUPERFAMILY SSF51717 45 219 1.73E-9 T 16-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 1.5E-130 T 16-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 PIRSF PIRSF004640 11 373 3.1E-147 T 16-09-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 SUPERFAMILY SSF56014 277 359 1.7E-11 T 16-09-2016 Spa2297_RS24115 a11ff88ca70fa7869a3f981155f88be0 385 Gene3D G3DSA:3.20.20.70 47 186 2.2E-4 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 PANTHER PTHR32282:SF0 25 701 1.8E-220 T 16-09-2016 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 636 2.4E-29 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 Gene3D G3DSA:1.10.3810.10 77 263 3.4E-71 T 16-09-2016 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 PANTHER PTHR32282 25 701 1.8E-220 T 16-09-2016 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 SUPERFAMILY SSF56601 243 265 1.27E-88 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 SUPERFAMILY SSF56601 299 678 1.27E-88 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 Pfam PF00912 Transglycosylase 77 261 5.1E-63 T 16-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 SUPERFAMILY SSF53955 64 286 4.5E-69 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS17825 9a0a56e34989694c50d4b8c891e58c7a 761 Gene3D G3DSA:3.40.710.10 264 699 4.5E-102 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 PANTHER PTHR24220 5 315 9.0E-150 T 16-09-2016 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 225 312 2.0E-20 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 293 3.8E-14 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 Pfam PF00005 ABC transporter 21 175 1.6E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 Gene3D G3DSA:3.40.50.300 3 247 1.1E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 PANTHER PTHR24220:SF586 5 315 9.0E-150 T 16-09-2016 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 SMART SM00382 29 233 2.7E-20 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24195 85d44b44c0d4ced0a69bdcabbcfe340e 345 SUPERFAMILY SSF52540 3 246 4.4E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 256 3.7E-95 T 16-09-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 SUPERFAMILY SSF53613 1 258 1.04E-77 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 Pfam PF08543 Phosphomethylpyrimidine kinase 13 255 1.1E-91 T 16-09-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 PANTHER PTHR20858:SF17 1 260 1.6E-115 T 16-09-2016 Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 PANTHER PTHR20858 1 260 1.6E-115 T 16-09-2016 Spa2297_RS23600 73a0ad22ca74c3c2e0d080a100d1340f 265 Gene3D G3DSA:3.40.1190.20 4 256 9.4E-100 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS24840 23be2516a3389e97761dc99ae0aab09c 98 Pfam PF13834 Domain of unknown function (DUF4193) 1 97 5.7E-45 T 16-09-2016 IPR025242 Protein of unknown function DUF4193 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 Gene3D G3DSA:3.40.605.10 24 280 5.4E-97 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 Gene3D G3DSA:3.40.309.10 281 471 1.0E-64 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 Pfam PF00171 Aldehyde dehydrogenase family 33 491 2.6E-171 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 PANTHER PTHR11699 1 495 0.0 T 16-09-2016 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 SUPERFAMILY SSF53720 22 494 2.09E-161 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24005 0ff4c9ab1e197c5a27fcbde1c5411a64 511 PANTHER PTHR11699:SF109 1 495 0.0 T 16-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 Gene3D G3DSA:1.10.10.10 3 80 5.1E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.5E-19 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 PANTHER PTHR30579 1 293 1.8E-95 T 16-09-2016 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.6E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.6E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.6E-7 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 SUPERFAMILY SSF46785 2 109 2.81E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 PANTHER PTHR30579:SF0 1 293 1.8E-95 T 16-09-2016 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 Gene3D G3DSA:3.40.190.10 187 242 5.1E-8 T 16-09-2016 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 SUPERFAMILY SSF53850 88 275 7.93E-32 T 16-09-2016 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 Gene3D G3DSA:3.40.190.10 86 186 1.2E-21 T 16-09-2016 Spa2297_RS27285 69f825fdabc5313a2b8dc79b4c327989 293 Pfam PF03466 LysR substrate binding domain 87 275 2.0E-34 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS31805 691a0ff9b7c6de05c90077094055d396 405 Gene3D G3DSA:3.40.50.2000 195 360 3.9E-11 T 16-09-2016 Spa2297_RS31805 691a0ff9b7c6de05c90077094055d396 405 Pfam PF13579 Glycosyl transferase 4-like domain 10 177 1.7E-19 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS31805 691a0ff9b7c6de05c90077094055d396 405 PANTHER PTHR12526 14 379 2.7E-54 T 16-09-2016 Spa2297_RS31805 691a0ff9b7c6de05c90077094055d396 405 SUPERFAMILY SSF53756 10 383 2.04E-61 T 16-09-2016 Spa2297_RS31805 691a0ff9b7c6de05c90077094055d396 405 Pfam PF13692 Glycosyl transferases group 1 201 347 1.6E-23 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 PANTHER PTHR18964:SF138 204 291 4.2E-114 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 PANTHER PTHR18964:SF138 1 180 4.2E-114 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 Gene3D G3DSA:3.30.420.40 130 273 2.9E-48 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 PANTHER PTHR18964 204 291 4.2E-114 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 PANTHER PTHR18964 1 180 4.2E-114 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 SUPERFAMILY SSF53067 2 292 5.1E-51 T 16-09-2016 Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 Pfam PF00480 ROK family 2 287 3.1E-54 T 16-09-2016 IPR000600 ROK family Spa2297_RS14850 ac318e51eb93bacc3fb1a6076df48e09 310 Gene3D G3DSA:3.30.420.40 1 129 2.0E-29 T 16-09-2016 Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 Gene3D G3DSA:3.40.50.1240 15 201 1.3E-30 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 SMART SM00855 14 166 6.6E-16 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 PANTHER PTHR23029 1 213 5.9E-107 T 16-09-2016 Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 16 202 5.5E-35 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 SUPERFAMILY SSF53254 14 204 7.22E-36 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS18785 44bde8d96503b08efc8f746ce22cda1a 232 PANTHER PTHR23029:SF35 1 213 5.9E-107 T 16-09-2016 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.1E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 SUPERFAMILY SSF46689 9 81 9.45E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 PANTHER PTHR30055:SF72 3 202 4.7E-59 T 16-09-2016 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 Gene3D G3DSA:1.10.357.10 8 201 4.3E-37 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 PANTHER PTHR30055 3 202 4.7E-59 T 16-09-2016 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.6E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29710 263317d85b33c85f95c73d915a270124 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.6E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14010 cfa1896815a7339b08422244355d0600 724 Pfam PF12805 FUSC-like inner membrane protein yccS 81 190 7.5E-5 T 16-09-2016 IPR032692 Integral membrane protein YccS, N-terminal Spa2297_RS14010 cfa1896815a7339b08422244355d0600 724 PANTHER PTHR30509:SF8 362 584 4.5E-23 T 16-09-2016 Spa2297_RS14010 cfa1896815a7339b08422244355d0600 724 Pfam PF13515 Fusaric acid resistance protein-like 388 509 1.1E-16 T 16-09-2016 Spa2297_RS14010 cfa1896815a7339b08422244355d0600 724 PANTHER PTHR30509 362 584 4.5E-23 T 16-09-2016 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 PANTHER PTHR30055 9 204 3.8E-50 T 16-09-2016 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 Gene3D G3DSA:1.10.10.60 13 67 1.6E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 5.1E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 195 7.2E-23 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 Gene3D G3DSA:1.10.357.10 68 202 4.8E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 PANTHER PTHR30055:SF66 9 204 3.8E-50 T 16-09-2016 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 SUPERFAMILY SSF46689 16 80 1.44E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24610 75dd312447b30d4df11034dbc8c06184 206 SUPERFAMILY SSF48498 87 202 8.56E-20 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS04175 9a7d60b418ea4a02002278dd7fbcc319 298 PANTHER PTHR36124 3 293 4.7E-215 T 16-09-2016 Spa2297_RS04175 9a7d60b418ea4a02002278dd7fbcc319 298 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 247 1.6E-19 T 16-09-2016 IPR018713 Domain of unknown function DUF2236 Spa2297_RS04175 9a7d60b418ea4a02002278dd7fbcc319 298 PANTHER PTHR36124:SF2 3 293 4.7E-215 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 292 2.7E-59 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 SUPERFAMILY SSF51905 1 276 1.0E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PANTHER PTHR22912 1 388 1.3E-131 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 Pfam PF14759 Reductase C-terminal 319 402 3.4E-25 T 16-09-2016 IPR028202 Reductase, C-terminal Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PANTHER PTHR22912:SF180 1 388 1.3E-131 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.5E-28 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 92 110 1.5E-28 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 1.5E-28 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 15 1.5E-28 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 223 239 1.5E-28 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 Gene3D G3DSA:3.30.390.30 319 402 5.1E-29 T 16-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 Gene3D G3DSA:3.50.50.60 98 304 2.4E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 SUPERFAMILY SSF55424 312 402 4.94E-27 T 16-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 272 1.4E-14 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 95 104 1.4E-14 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 161 1.4E-14 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 224 238 1.4E-14 T 16-09-2016 Spa2297_RS08635 c5a2099e2618efaf5d1b20e483f7fd48 404 Gene3D G3DSA:3.50.50.60 1 97 9.4E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08750 73cbf5f35acaf1a02a4d518c5ebdfb76 390 PANTHER PTHR10803 1 380 1.2E-161 T 16-09-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Spa2297_RS08750 73cbf5f35acaf1a02a4d518c5ebdfb76 390 PANTHER PTHR10803:SF9 1 380 1.2E-161 T 16-09-2016 Spa2297_RS08750 73cbf5f35acaf1a02a4d518c5ebdfb76 390 Gene3D G3DSA:3.40.50.300 1 286 3.9E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08750 73cbf5f35acaf1a02a4d518c5ebdfb76 390 SUPERFAMILY SSF52540 1 285 1.73E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08750 73cbf5f35acaf1a02a4d518c5ebdfb76 390 Pfam PF02374 Anion-transporting ATPase 1 292 9.3E-31 T 16-09-2016 IPR025723 Anion-transporting ATPase-like domain Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 Pfam PF13229 Right handed beta helix region 443 621 5.6E-8 T 16-09-2016 Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 Gene3D G3DSA:2.160.20.10 36 126 2.1E-11 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 Gene3D G3DSA:2.160.20.10 427 464 3.7E-7 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 Gene3D G3DSA:2.160.20.10 502 684 3.7E-7 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 SUPERFAMILY SSF51126 437 461 1.39E-23 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 SUPERFAMILY SSF51126 501 704 1.39E-23 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS32075 655f9a03abbdf5f0385660058b6e2433 888 SUPERFAMILY SSF51126 44 132 1.39E-23 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 SMART SM00530 9 82 9.7E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 PANTHER PTHR35010:SF1 1 271 2.3E-109 T 16-09-2016 Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 Pfam PF13560 Helix-turn-helix domain 5 85 2.1E-15 T 16-09-2016 Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 PANTHER PTHR35010 1 271 2.3E-109 T 16-09-2016 Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 Gene3D G3DSA:1.10.260.40 4 81 1.3E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS32195 8bd634f4348fed415e740d96f6469223 277 SUPERFAMILY SSF47413 29 81 8.16E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 PANTHER PTHR10859:SF75 27 341 1.3E-98 T 16-09-2016 Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 8 383 7.1E-144 T 16-09-2016 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 PANTHER PTHR10859 27 341 1.3E-98 T 16-09-2016 Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 Gene3D G3DSA:3.90.550.10 44 252 2.4E-20 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 SUPERFAMILY SSF53448 37 253 6.67E-36 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS03385 7403309a411785a41ee0df8713c9dfa2 392 Pfam PF13641 Glycosyltransferase like family 2 44 252 6.1E-21 T 16-09-2016 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 Gene3D G3DSA:1.10.357.10 96 276 2.2E-39 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 SMART SM00530 18 73 6.1E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 SUPERFAMILY SSF46689 94 165 6.67E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 SUPERFAMILY SSF48498 163 275 1.17E-21 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 SUPERFAMILY SSF47413 18 75 1.98E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 Pfam PF00440 Bacterial regulatory proteins, tetR family 97 143 5.4E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 97 110 4.8E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 118 141 4.8E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 Gene3D G3DSA:1.10.260.40 17 76 7.2E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 Pfam PF13977 Bacterial transcriptional repressor 166 277 1.1E-27 T 16-09-2016 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 PANTHER PTHR30328:SF11 71 256 6.0E-31 T 16-09-2016 Spa2297_RS03245 010c92ab8496da8e2233007b582a9d48 285 PANTHER PTHR30328 71 256 6.0E-31 T 16-09-2016 Spa2297_RS27980 4fd00b5338c2226d1c0502251d39b866 227 Gene3D G3DSA:1.10.3630.10 4 220 2.0E-26 T 16-09-2016 Spa2297_RS27980 4fd00b5338c2226d1c0502251d39b866 227 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 210 3.5E-34 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 SUPERFAMILY SSF52172 1 133 2.13E-27 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 Pfam PF00072 Response regulator receiver domain 5 123 5.5E-19 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 Gene3D G3DSA:2.40.50.40 145 214 4.2E-15 T 16-09-2016 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 Pfam PF04397 LytTr DNA-binding domain 158 248 2.2E-21 T 16-09-2016 IPR007492 LytTR DNA-binding domain GO:0003677 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 PANTHER PTHR26402 2 140 1.6E-24 T 16-09-2016 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 PANTHER PTHR26402 215 239 1.6E-24 T 16-09-2016 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 SMART SM00448 2 122 4.8E-20 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 Gene3D G3DSA:3.40.50.2300 1 134 2.2E-27 T 16-09-2016 Spa2297_RS04415 8134d14c60cdaf15fa4f009d183880cd 252 SMART SM00850 154 249 5.1E-27 T 16-09-2016 IPR007492 LytTR DNA-binding domain GO:0003677 Spa2297_RS06830 7e23568c13a5aa9c8613c6dc17b2530b 294 PANTHER PTHR10992:SF771 59 238 1.5E-12 T 16-09-2016 Spa2297_RS06830 7e23568c13a5aa9c8613c6dc17b2530b 294 Gene3D G3DSA:3.40.50.1820 37 290 9.7E-79 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS06830 7e23568c13a5aa9c8613c6dc17b2530b 294 SUPERFAMILY SSF53474 55 238 1.02E-29 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS06830 7e23568c13a5aa9c8613c6dc17b2530b 294 PANTHER PTHR10992 59 238 1.5E-12 T 16-09-2016 Spa2297_RS06830 7e23568c13a5aa9c8613c6dc17b2530b 294 Pfam PF01674 Lipase (class 2) 59 233 1.4E-12 T 16-09-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 PRINTS PR00046 Major sigma-70 factor signature 247 262 4.7E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 PRINTS PR00046 Major sigma-70 factor signature 83 96 4.7E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 PRINTS PR00046 Major sigma-70 factor signature 230 242 4.7E-9 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Pfam PF04545 Sigma-70, region 4 227 275 3.1E-17 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Gene3D G3DSA:1.10.10.10 222 276 3.4E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 54 275 4.6E-31 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 PANTHER PTHR30385 29 280 3.2E-103 T 16-09-2016 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Pfam PF04539 Sigma-70 region 3 138 205 1.7E-13 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 PANTHER PTHR30385:SF4 29 280 3.2E-103 T 16-09-2016 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 52 277 6.4E-88 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 SUPERFAMILY SSF88659 194 277 2.99E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Gene3D G3DSA:1.10.601.10 44 126 1.2E-22 T 16-09-2016 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 SUPERFAMILY SSF88946 16 128 1.16E-30 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Pfam PF04542 Sigma-70 region 2 58 128 3.6E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 83 96 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 Gene3D G3DSA:1.10.10.10 127 182 8.0E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30650 2c323959ff06397f3d764c6a5dc0401f 281 SUPERFAMILY SSF88659 132 208 4.36E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20600 60fbbd71fb1fa53bd0bad8880dba9448 376 Pfam PF01757 Acyltransferase family 31 356 5.1E-21 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS20600 60fbbd71fb1fa53bd0bad8880dba9448 376 PANTHER PTHR23028:SF79 2 374 2.9E-67 T 16-09-2016 Spa2297_RS20600 60fbbd71fb1fa53bd0bad8880dba9448 376 PANTHER PTHR23028 2 374 2.9E-67 T 16-09-2016 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 SUPERFAMILY SSF52540 20 243 2.6E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 SUPERFAMILY SSF50331 243 353 2.08E-18 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 Gene3D G3DSA:3.40.50.300 28 240 7.8E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 Pfam PF00005 ABC transporter 28 168 8.6E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 SMART SM00382 35 218 1.7E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 PANTHER PTHR24220:SF543 12 247 4.5E-132 T 16-09-2016 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 PANTHER PTHR24220 12 247 4.5E-132 T 16-09-2016 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 Gene3D G3DSA:2.40.50.100 282 348 3.4E-16 T 16-09-2016 Spa2297_RS17210 030f393e872acf12de8bad48d4fef0df 356 Pfam PF03459 TOBE domain 292 352 5.0E-14 T 16-09-2016 IPR005116 Transport-associated OB, type 1 Spa2297_RS11765 2ab43bfde18cca70beb46667c9e7e3fb 321 PANTHER PTHR10277 2 310 8.9E-162 T 16-09-2016 Spa2297_RS11765 2ab43bfde18cca70beb46667c9e7e3fb 321 PANTHER PTHR10277:SF1 2 310 8.9E-162 T 16-09-2016 Spa2297_RS11765 2ab43bfde18cca70beb46667c9e7e3fb 321 Gene3D G3DSA:3.20.20.70 19 305 5.2E-80 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS11765 2ab43bfde18cca70beb46667c9e7e3fb 321 Pfam PF00682 HMGL-like 20 291 1.9E-45 T 16-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spa2297_RS11765 2ab43bfde18cca70beb46667c9e7e3fb 321 SUPERFAMILY SSF51569 17 306 2.01E-66 T 16-09-2016 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 SUPERFAMILY SSF56524 272 423 5.49E-34 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 Pfam PF00174 Oxidoreductase molybdopterin binding domain 287 422 1.5E-22 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 327 342 3.7E-8 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 393 406 3.7E-8 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 376 392 3.7E-8 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 409 422 3.7E-8 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PANTHER PTHR19372:SF2 1 425 5.0E-134 T 16-09-2016 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 PANTHER PTHR19372 1 425 5.0E-134 T 16-09-2016 Spa2297_RS17125 27cd42f805c9b2244e91d86788d9f8e4 425 Gene3D G3DSA:3.90.420.10 283 422 3.6E-31 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS17235 a34a04fea9c428c864c73b492e27afc5 273 PANTHER PTHR11908:SF68 20 168 9.5E-26 T 16-09-2016 Spa2297_RS17235 a34a04fea9c428c864c73b492e27afc5 273 Gene3D G3DSA:3.30.465.10 57 169 4.6E-24 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS17235 a34a04fea9c428c864c73b492e27afc5 273 PANTHER PTHR11908 20 168 9.5E-26 T 16-09-2016 Spa2297_RS17235 a34a04fea9c428c864c73b492e27afc5 273 SUPERFAMILY SSF56176 20 169 7.09E-28 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS17235 a34a04fea9c428c864c73b492e27afc5 273 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 25 169 3.4E-19 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 Gene3D G3DSA:1.10.10.10 157 216 1.2E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 Gene3D G3DSA:3.40.50.2300 2 156 8.5E-41 T 16-09-2016 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 Pfam PF00072 Response regulator receiver domain 4 114 1.8E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 SUPERFAMILY SSF52172 2 134 8.82E-35 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 PANTHER PTHR26402:SF151 2 217 2.6E-72 T 16-09-2016 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 211 1.4E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 SUPERFAMILY SSF46894 148 218 1.63E-18 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 SMART SM00448 2 115 1.4E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 PANTHER PTHR26402 2 217 2.6E-72 T 16-09-2016 Spa2297_RS18405 da5739a3af4a7f3bdc7ee41d14b5f4c7 221 SMART SM00421 154 211 5.2E-21 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS02340 dd9bf14d367303a89265f04aacda0b15 171 Gene3D G3DSA:1.20.120.450 1 167 2.9E-69 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS02340 dd9bf14d367303a89265f04aacda0b15 171 Pfam PF04978 Protein of unknown function (DUF664) 13 166 1.4E-16 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS02340 dd9bf14d367303a89265f04aacda0b15 171 SUPERFAMILY SSF109854 4 165 8.85E-32 T 16-09-2016 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 Pfam PF00005 ABC transporter 23 174 4.2E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 Pfam PF00005 ABC transporter 279 430 1.1E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 SMART SM00382 32 222 2.9E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 SMART SM00382 285 479 2.5E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 Gene3D G3DSA:3.40.50.300 4 230 5.5E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 SUPERFAMILY SSF52540 248 491 1.96E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 Gene3D G3DSA:3.40.50.300 278 492 1.9E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 PANTHER PTHR24220 9 385 8.4E-256 T 16-09-2016 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 PANTHER PTHR24220:SF502 9 385 8.4E-256 T 16-09-2016 Spa2297_RS27345 3d42bbd86b7919dcb22605d2fefda8cc 505 SUPERFAMILY SSF52540 6 230 6.06E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 Gene3D G3DSA:3.20.20.100 1 308 4.5E-108 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 PRINTS PR00069 Aldo-keto reductase signature 241 265 8.5E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 PRINTS PR00069 Aldo-keto reductase signature 42 66 8.5E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 PRINTS PR00069 Aldo-keto reductase signature 108 126 8.5E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 Pfam PF00248 Aldo/keto reductase family 13 306 4.9E-77 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 PANTHER PTHR11732:SF215 1 304 1.6E-135 T 16-09-2016 Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 PANTHER PTHR11732 1 304 1.6E-135 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS01855 2c9b647277613315fff81dd4dc76deb7 325 SUPERFAMILY SSF51430 7 307 9.56E-98 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 Pfam PF07690 Major Facilitator Superfamily 37 296 5.9E-26 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 PANTHER PTHR11360 25 431 9.1E-182 T 16-09-2016 Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 Gene3D G3DSA:1.20.1250.20 248 433 1.9E-17 T 16-09-2016 Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 Gene3D G3DSA:1.20.1250.20 27 218 3.1E-29 T 16-09-2016 Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 SUPERFAMILY SSF103473 14 432 3.66E-66 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14375 05397d69fc27d5e7cd342d0de360cf7e 441 PANTHER PTHR11360:SF115 25 431 9.1E-182 T 16-09-2016 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PANTHER PTHR10804 4 283 2.7E-142 T 16-09-2016 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.4E-53 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 SUPERFAMILY SSF55920 41 283 8.9E-86 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 1.9E-90 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PANTHER PTHR10804:SF82 4 283 2.7E-142 T 16-09-2016 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 Gene3D G3DSA:3.90.230.10 41 284 2.2E-96 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.46 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.6E-20 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.6E-20 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.6E-20 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS09460 a15ad5830bb64b4210f418cd78a4f12a 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.6E-20 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS22235 8326a5250f336cda73e852ea77814cb8 131 Gene3D G3DSA:1.20.120.400 15 130 1.0E-49 T 16-09-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 Spa2297_RS22235 8326a5250f336cda73e852ea77814cb8 131 SUPERFAMILY SSF109770 15 131 8.76E-55 T 16-09-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 Spa2297_RS22235 8326a5250f336cda73e852ea77814cb8 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 1.2E-42 T 16-09-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 Spa2297_RS22235 8326a5250f336cda73e852ea77814cb8 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 131 4.9E-59 T 16-09-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742:SF287 7 98 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742:SF287 120 141 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PRINTS PR00757 Flavin-containing amine oxidase signature 427 444 3.8E-5 T 16-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 3.8E-5 T 16-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 SUPERFAMILY SSF51905 404 449 4.61E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 SUPERFAMILY SSF51905 8 320 4.61E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742 120 141 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742:SF287 173 450 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 Gene3D G3DSA:3.50.50.60 409 450 8.6E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 Gene3D G3DSA:3.50.50.60 243 310 8.6E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 Gene3D G3DSA:3.50.50.60 8 46 8.6E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742 173 450 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 PANTHER PTHR10742 7 98 7.4E-31 T 16-09-2016 Spa2297_RS09060 8555963361533c04013fab3d4fba35d6 467 Pfam PF01593 Flavin containing amine oxidoreductase 17 446 2.7E-41 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 1.2E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 PANTHER PTHR30055:SF93 24 256 2.8E-30 T 16-09-2016 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 263 1.9E-13 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 Gene3D G3DSA:1.10.357.10 29 268 4.3E-58 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 SUPERFAMILY SSF48498 104 267 2.0E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 PANTHER PTHR30055 24 256 2.8E-30 T 16-09-2016 Spa2297_RS02645 6deb8793a7a318121f2ebca7140101c9 280 SUPERFAMILY SSF46689 31 97 1.18E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31460 c87c4880d4b2fbf347704868f8a7911e 251 PANTHER PTHR34310 31 251 1.5E-107 T 16-09-2016 Spa2297_RS31460 c87c4880d4b2fbf347704868f8a7911e 251 Pfam PF04248 Domain of unknown function (DUF427) 147 239 3.8E-26 T 16-09-2016 IPR007361 Domain of unknown function DUF427 Spa2297_RS31460 c87c4880d4b2fbf347704868f8a7911e 251 PANTHER PTHR34310:SF4 31 251 1.5E-107 T 16-09-2016 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 Gene3D G3DSA:3.40.50.720 154 243 2.8E-24 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 100 2.3E-10 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 SUPERFAMILY SSF51735 121 283 5.69E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 SMART SM00829 14 323 6.2E-43 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 PANTHER PTHR11695:SF294 20 310 7.1E-98 T 16-09-2016 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 Pfam PF13602 Zinc-binding dehydrogenase 191 310 4.0E-27 T 16-09-2016 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 PANTHER PTHR11695 20 310 7.1E-98 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 Gene3D G3DSA:3.90.180.10 4 153 1.5E-46 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31985 69898ffc0d29bae611518a3e0f20dc37 327 SUPERFAMILY SSF50129 2 154 9.74E-38 T 16-09-2016 IPR011032 GroES-like Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SMART SM00465 17 99 4.0E-20 T 16-09-2016 IPR000305 GIY-YIG nuclease superfamily Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Gene3D G3DSA:3.40.1440.10 18 95 4.9E-10 T 16-09-2016 IPR027299 GIY-YIG domain Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 647 5.0E-52 T 16-09-2016 IPR001162 UvrC family homology region Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 PANTHER PTHR30562:SF1 1 466 5.1E-267 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 PANTHER PTHR30562:SF1 573 713 5.1E-267 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 PANTHER PTHR30562 573 713 5.1E-267 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Pfam PF01541 GIY-YIG catalytic domain 19 92 3.1E-11 T 16-09-2016 IPR000305 GIY-YIG nuclease superfamily Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 712 30.531 T 16-09-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Pfam PF14520 Helix-hairpin-helix domain 663 713 3.1E-10 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SUPERFAMILY SSF47781 604 714 4.45E-25 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SMART SM00278 693 712 0.42 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SMART SM00278 661 680 19.0 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SUPERFAMILY SSF82771 17 101 6.15E-23 T 16-09-2016 IPR000305 GIY-YIG nuclease superfamily Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 PANTHER PTHR30562 1 466 5.1E-267 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 SUPERFAMILY SSF46600 194 246 4.18E-13 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 12 466 1.2E-129 T 16-09-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Gene3D G3DSA:1.10.150.20 661 710 9.0E-21 T 16-09-2016 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Pfam PF02151 UvrB/uvrC motif 210 242 4.9E-11 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS07875 a7414c5c243d4bf5d8d5f8db8e53b5f9 762 Gene3D G3DSA:4.10.860.10 187 246 1.2E-17 T 16-09-2016 IPR001943 UVR domain GO:0005515 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 SUPERFAMILY SSF48264 19 414 4.06E-59 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 Gene3D G3DSA:1.10.630.10 13 414 2.4E-84 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PANTHER PTHR11712 38 413 1.7E-59 T 16-09-2016 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 353 362 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 306 333 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 113 124 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 210 232 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 159 175 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PRINTS PR00359 B-class P450 signature 288 299 3.5E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS29830 666aa4d2a08f077c4613dc95ac07ad4e 415 PANTHER PTHR11712:SF282 38 413 1.7E-59 T 16-09-2016 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 TIGRFAM TIGR00876 tal_mycobact: transaldolase 20 366 1.4E-125 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 SUPERFAMILY SSF51569 17 371 1.01E-77 T 16-09-2016 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 ProSitePatterns PS00958 Transaldolase active site. 146 163 - T 16-09-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 Pfam PF00923 Transaldolase 24 367 9.7E-82 T 16-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 PIRSF PIRSF036915 3 380 1.1E-175 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 PANTHER PTHR10683:SF12 10 375 1.3E-247 T 16-09-2016 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 ProSitePatterns PS01054 Transaldolase signature 1. 50 58 - T 16-09-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 PANTHER PTHR10683 10 375 1.3E-247 T 16-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 Hamap MF_00493 Transaldolase [tal]. 1 379 153.84 T 16-09-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 Spa2297_RS27705 a8b1a3056d65a25b97cda0ebe02afede 381 Gene3D G3DSA:3.20.20.70 13 369 2.0E-121 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 Pfam PF08386 TAP-like protein 401 495 1.7E-26 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 Pfam PF00561 alpha/beta hydrolase fold 90 272 1.2E-17 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992:SF107 46 138 3.4E-47 T 16-09-2016 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992:SF107 367 485 3.4E-47 T 16-09-2016 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 Gene3D G3DSA:3.40.50.1820 363 483 3.1E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 Gene3D G3DSA:3.40.50.1820 54 139 3.1E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 Gene3D G3DSA:3.40.50.1820 183 309 3.1E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992 46 138 3.4E-47 T 16-09-2016 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992 367 485 3.4E-47 T 16-09-2016 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992:SF107 182 283 3.4E-47 T 16-09-2016 Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 SUPERFAMILY SSF53474 80 134 4.51E-21 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 SUPERFAMILY SSF53474 403 468 4.51E-21 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 SUPERFAMILY SSF53474 174 345 4.51E-21 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10600 a738ea51c05d3b4c90019f565f9f76fa 497 PANTHER PTHR10992 182 283 3.4E-47 T 16-09-2016 Spa2297_RS25495 9340dda25fa9ed164e087e35d3799c39 151 SUPERFAMILY SSF52402 31 146 2.18E-19 T 16-09-2016 Spa2297_RS25495 9340dda25fa9ed164e087e35d3799c39 151 Gene3D G3DSA:3.40.50.620 62 146 2.2E-10 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 SUPERFAMILY SSF52518 9 178 7.99E-46 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 326 3.7E-24 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 PANTHER PTHR18968:SF6 1 560 5.5E-152 T 16-09-2016 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 176 8.7E-50 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 542 2.8E-29 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 SUPERFAMILY SSF52518 370 552 4.11E-48 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 16-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 PANTHER PTHR18968 1 560 5.5E-152 T 16-09-2016 Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Gene3D G3DSA:3.40.50.970 8 181 2.9E-58 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 SUPERFAMILY SSF52467 195 375 5.01E-35 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Gene3D G3DSA:3.40.50.970 342 551 1.3E-51 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS27430 9d4225fbe51b356fd8f13fef278345c8 560 Gene3D G3DSA:3.40.50.1220 191 334 1.4E-35 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 Gene3D G3DSA:1.10.510.10 105 262 6.7E-41 T 16-09-2016 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 Gene3D G3DSA:3.30.200.20 11 80 7.9E-14 T 16-09-2016 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 Pfam PF00069 Protein kinase domain 15 262 3.9E-37 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 SMART SM00220 15 265 6.6E-47 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 SUPERFAMILY SSF56112 13 267 1.48E-64 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 PANTHER PTHR24362 6 265 1.5E-94 T 16-09-2016 Spa2297_RS18920 8d12b7fb658583cab07590d2b94800d2 646 PANTHER PTHR24362:SF247 6 265 1.5E-94 T 16-09-2016 Spa2297_RS31990 ce653e4dcb484d5507e6808f457d6038 102 Pfam PF12840 Helix-turn-helix domain 9 79 8.8E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31990 ce653e4dcb484d5507e6808f457d6038 102 Gene3D G3DSA:1.10.10.10 4 100 2.9E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31990 ce653e4dcb484d5507e6808f457d6038 102 SUPERFAMILY SSF46785 6 100 7.37E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31990 ce653e4dcb484d5507e6808f457d6038 102 PANTHER PTHR33154 5 102 1.5E-23 T 16-09-2016 Spa2297_RS31990 ce653e4dcb484d5507e6808f457d6038 102 SMART SM00418 9 100 2.6E-14 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 Gene3D G3DSA:3.90.180.10 2 165 6.9E-36 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 Pfam PF00107 Zinc-binding dehydrogenase 173 298 1.7E-17 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 PANTHER PTHR11695 7 337 1.7E-102 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 SUPERFAMILY SSF50129 2 161 1.98E-44 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 21 122 2.2E-23 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 PANTHER PTHR11695:SF601 7 337 1.7E-102 T 16-09-2016 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 SMART SM00829 3 335 8.9E-4 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 Gene3D G3DSA:3.40.50.720 166 282 2.1E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01860 c034081103842c2a9f562951f620dd9a 337 SUPERFAMILY SSF51735 142 305 1.01E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16290 7c4c9ad621f2ac8fc33910e34990a72a 334 PANTHER PTHR30365:SF6 1 334 7.3E-141 T 16-09-2016 Spa2297_RS16290 7c4c9ad621f2ac8fc33910e34990a72a 334 PIRSF PIRSF000267 1 334 6.2E-121 T 16-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Spa2297_RS16290 7c4c9ad621f2ac8fc33910e34990a72a 334 PANTHER PTHR30365 1 334 7.3E-141 T 16-09-2016 Spa2297_RS16290 7c4c9ad621f2ac8fc33910e34990a72a 334 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 214 1.5E-76 T 16-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Spa2297_RS16290 7c4c9ad621f2ac8fc33910e34990a72a 334 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 2.2E-116 T 16-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Spa2297_RS24980 e8a4dad05d343cebee5ec1d91dd94aea 499 PIRSF PIRSF006060 5 483 1.4E-43 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS24980 e8a4dad05d343cebee5ec1d91dd94aea 499 Pfam PF13520 Amino acid permease 26 434 1.1E-24 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS24980 e8a4dad05d343cebee5ec1d91dd94aea 499 PANTHER PTHR11785 13 480 2.8E-30 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS29440 7247b6c7b7910da1054f8b87fb5e75eb 210 PANTHER PTHR30246 2 210 2.6E-72 T 16-09-2016 Spa2297_RS29440 7247b6c7b7910da1054f8b87fb5e75eb 210 SUPERFAMILY SSF51569 4 205 2.93E-51 T 16-09-2016 Spa2297_RS29440 7247b6c7b7910da1054f8b87fb5e75eb 210 Pfam PF01081 KDPG and KHG aldolase 7 183 9.9E-38 T 16-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spa2297_RS29440 7247b6c7b7910da1054f8b87fb5e75eb 210 Gene3D G3DSA:3.20.20.70 4 209 5.9E-62 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS29440 7247b6c7b7910da1054f8b87fb5e75eb 210 PANTHER PTHR30246:SF1 2 210 2.6E-72 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 Pfam PF05787 Bacterial protein of unknown function (DUF839) 147 449 3.4E-74 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 Pfam PF05787 Bacterial protein of unknown function (DUF839) 47 143 3.3E-15 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 SUPERFAMILY SSF50956 328 448 1.44E-10 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 Gene3D G3DSA:2.130.10.10 342 445 1.6E-6 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 PANTHER PTHR35399 15 460 2.9E-169 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 PANTHER PTHR35399:SF1 15 460 2.9E-169 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 SUPERFAMILY SSF63829 76 139 2.09E-5 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 SUPERFAMILY SSF63829 345 402 2.09E-5 T 16-09-2016 Spa2297_RS25460 09906d440cae948ca3bde6985a9c53d5 460 SUPERFAMILY SSF63829 183 233 2.09E-5 T 16-09-2016 Spa2297_RS25045 ebbc66b18ab2b19e00d8dd7415cf4fa0 112 Pfam PF02553 Cobalt transport protein component CbiN 8 78 2.4E-29 T 16-09-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 Spa2297_RS25045 ebbc66b18ab2b19e00d8dd7415cf4fa0 112 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 112 43.625 T 16-09-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 Spa2297_RS25045 ebbc66b18ab2b19e00d8dd7415cf4fa0 112 PANTHER PTHR38662 3 105 1.3E-43 T 16-09-2016 Spa2297_RS25045 ebbc66b18ab2b19e00d8dd7415cf4fa0 112 TIGRFAM TIGR01165 cbiN: cobalt transport protein 3 93 1.7E-40 T 16-09-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 Gene3D G3DSA:2.60.120.10 91 215 1.3E-21 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 SUPERFAMILY SSF51206 100 214 4.32E-21 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 PANTHER PTHR24567 6 215 1.3E-244 T 16-09-2016 Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 PANTHER PTHR24567 283 468 1.3E-244 T 16-09-2016 Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 PANTHER PTHR24567:SF37 283 468 1.3E-244 T 16-09-2016 Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 Pfam PF00027 Cyclic nucleotide-binding domain 114 200 5.5E-16 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 SMART SM00100 94 217 2.1E-11 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS22215 ad1ce4aa96f2f557ba979d122faddf06 468 PANTHER PTHR24567:SF37 6 215 1.3E-244 T 16-09-2016 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 SUPERFAMILY SSF53686 5 295 5.5E-88 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 PANTHER PTHR10314 1 298 2.0E-181 T 16-09-2016 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 PANTHER PTHR10314:SF100 1 298 2.0E-181 T 16-09-2016 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 16-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 Gene3D G3DSA:3.40.50.1100 42 143 2.5E-38 T 16-09-2016 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 6.7E-111 T 16-09-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 5.4E-69 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 Gene3D G3DSA:3.40.50.1100 149 301 1.7E-67 T 16-09-2016 Spa2297_RS12450 58a64c3abfb55a91338359b6198cfe9a 316 Gene3D G3DSA:3.40.50.1100 1 41 1.7E-67 T 16-09-2016 Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 41 5.9E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 SUPERFAMILY SSF46689 2 56 7.7E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 Gene3D G3DSA:1.10.357.10 2 172 1.2E-33 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 Pfam PF13977 Bacterial transcriptional repressor 67 174 1.6E-9 T 16-09-2016 Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 SUPERFAMILY SSF48498 62 171 7.53E-15 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS00530 be98446540d27ff38634724c6d6ffb80 183 PANTHER PTHR30055 2 173 6.3E-13 T 16-09-2016 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 PANTHER PTHR33164:SF15 15 130 6.4E-52 T 16-09-2016 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 4.6E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 4.6E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 4.6E-6 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 Pfam PF12802 MarR family 37 101 7.1E-10 T 16-09-2016 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 SMART SM00347 32 137 1.2E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 Gene3D G3DSA:1.10.10.10 7 146 2.6E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 PANTHER PTHR33164 15 130 6.4E-52 T 16-09-2016 Spa2297_RS16400 b6dfb4a72aec101b6883ee62c9854bda 154 SUPERFAMILY SSF46785 13 134 1.96E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24200 b93bbdf628da0fd4df4dc1fa051fef33 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 311 1.0E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24200 b93bbdf628da0fd4df4dc1fa051fef33 315 PANTHER PTHR30465 26 313 8.7E-99 T 16-09-2016 Spa2297_RS24200 b93bbdf628da0fd4df4dc1fa051fef33 315 SUPERFAMILY SSF161098 104 295 2.35E-27 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24200 b93bbdf628da0fd4df4dc1fa051fef33 315 PANTHER PTHR30465:SF2 26 313 8.7E-99 T 16-09-2016 Spa2297_RS24200 b93bbdf628da0fd4df4dc1fa051fef33 315 Gene3D G3DSA:1.10.3720.10 105 309 9.3E-28 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PANTHER PTHR23501:SF7 441 477 3.3E-184 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 SUPERFAMILY SSF103473 3 192 9.81E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 SUPERFAMILY SSF103473 240 411 9.81E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 SUPERFAMILY SSF103473 448 474 9.81E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 4.9E-10 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 154 4.9E-10 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 4.9E-10 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 4.9E-10 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PANTHER PTHR23501 2 423 3.3E-184 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PANTHER PTHR23501:SF7 2 423 3.3E-184 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 PANTHER PTHR23501 441 477 3.3E-184 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 Pfam PF07690 Major Facilitator Superfamily 10 401 8.4E-48 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 Gene3D G3DSA:1.20.1250.20 257 412 5.4E-15 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 Gene3D G3DSA:1.20.1250.20 7 187 5.9E-28 T 16-09-2016 Spa2297_RS27275 51d06915ab46e6c8f852a818bdf0521a 501 Gene3D G3DSA:1.20.1250.20 449 474 5.4E-15 T 16-09-2016 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 Gene3D G3DSA:3.40.800.20 4 336 3.5E-85 T 16-09-2016 IPR023801 Histone deacetylase domain Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 Pfam PF00850 Histone deacetylase domain 22 316 3.6E-69 T 16-09-2016 IPR023801 Histone deacetylase domain Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PANTHER PTHR10625:SF10 16 344 7.1E-119 T 16-09-2016 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 SUPERFAMILY SSF52768 6 347 1.73E-98 T 16-09-2016 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 5.8E-18 T 16-09-2016 IPR000286 Histone deacetylase superfamily Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 5.8E-18 T 16-09-2016 IPR000286 Histone deacetylase superfamily Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 5.8E-18 T 16-09-2016 IPR000286 Histone deacetylase superfamily Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PANTHER PTHR10625 16 344 7.1E-119 T 16-09-2016 IPR000286 Histone deacetylase superfamily Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 307 326 3.5E-9 T 16-09-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 3.5E-9 T 16-09-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 3.5E-9 T 16-09-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 Spa2297_RS18535 6fee09e6b8fa805623303a2adac44eca 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 3.5E-9 T 16-09-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 Spa2297_RS03215 69cdd5d9f3dc6cf055e429118eafe750 434 Pfam PF01547 Bacterial extracellular solute-binding protein 54 348 2.0E-48 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS03215 69cdd5d9f3dc6cf055e429118eafe750 434 Gene3D G3DSA:3.40.190.10 35 215 5.3E-40 T 16-09-2016 Spa2297_RS03215 69cdd5d9f3dc6cf055e429118eafe750 434 SUPERFAMILY SSF53850 25 430 2.04E-77 T 16-09-2016 Spa2297_RS03215 69cdd5d9f3dc6cf055e429118eafe750 434 PANTHER PTHR30061:SF23 4 431 1.3E-254 T 16-09-2016 Spa2297_RS03215 69cdd5d9f3dc6cf055e429118eafe750 434 PANTHER PTHR30061 4 431 1.3E-254 T 16-09-2016 Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 PANTHER PTHR10996 1 329 2.6E-129 T 16-09-2016 Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 PANTHER PTHR10996:SF167 1 329 2.6E-129 T 16-09-2016 Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 Gene3D G3DSA:3.40.50.720 19 128 1.1E-11 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 Gene3D G3DSA:3.40.50.720 129 299 1.2E-51 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 SUPERFAMILY SSF51735 112 298 1.29E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 SUPERFAMILY SSF52283 25 139 1.97E-6 T 16-09-2016 Spa2297_RS32120 bb6d7458d6b53348f82c3db9eb11bdc7 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 297 2.9E-48 T 16-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 PANTHER PTHR38444:SF1 1 66 4.4E-36 T 16-09-2016 Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 SMART SM00923 3 53 5.2E-29 T 16-09-2016 IPR005153 MbtH-like protein Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 SUPERFAMILY SSF160582 1 65 6.02E-30 T 16-09-2016 Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 PANTHER PTHR38444 1 66 4.4E-36 T 16-09-2016 Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 Pfam PF03621 MbtH-like protein 1 53 2.9E-27 T 16-09-2016 IPR005153 MbtH-like protein Spa2297_RS02700 2d7ea8bbff8334f0b6a59d9d92b78c57 66 Gene3D G3DSA:3.90.820.10 11 66 3.5E-30 T 16-09-2016 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 16-09-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 340 42.942 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PIRSF PIRSF000532 1 339 2.7E-116 T 16-09-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 8.7E-75 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 PANTHER PTHR13697 1 336 7.7E-133 T 16-09-2016 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 Gene3D G3DSA:3.40.50.450 1 211 7.6E-74 T 16-09-2016 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 SUPERFAMILY SSF53784 1 332 3.53E-118 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 Pfam PF00365 Phosphofructokinase 2 297 4.3E-102 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS04390 dbd0cf68931e924ca015e10a9f42498a 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 1.5E-149 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 PANTHER PTHR19278 44 237 1.0E-75 T 16-09-2016 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 PANTHER PTHR19278 1 28 1.0E-75 T 16-09-2016 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 SMART SM00934 20 266 3.8E-32 T 16-09-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 Gene3D G3DSA:3.20.20.70 9 272 5.3E-61 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 SUPERFAMILY SSF51366 7 270 2.45E-61 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 94 107 - T 16-09-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 280 34.14 T 16-09-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 20 264 9.8E-40 T 16-09-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 7 266 5.2E-82 T 16-09-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 PANTHER PTHR19278:SF1 44 237 1.0E-75 T 16-09-2016 Spa2297_RS05575 984906f605b9cef8836a9dcfe4a115db 281 PANTHER PTHR19278:SF1 1 28 1.0E-75 T 16-09-2016 Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 PANTHER PTHR24220:SF568 6 238 2.7E-134 T 16-09-2016 Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 SUPERFAMILY SSF52540 4 236 2.11E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 Gene3D G3DSA:3.40.50.300 3 232 1.2E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 PIRSF PIRSF039137 1 238 2.8E-111 T 16-09-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 SMART SM00382 29 231 5.1E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 Pfam PF00005 ABC transporter 21 165 5.1E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 PANTHER PTHR24220 6 238 2.7E-134 T 16-09-2016 Spa2297_RS08180 904bc2ee9d31d2df0de217a269690eb1 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 Pfam PF01386 Ribosomal L25p family 7 91 2.3E-23 T 16-09-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 94 5.0E-41 T 16-09-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 Gene3D G3DSA:2.40.240.10 4 93 1.4E-26 T 16-09-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 SUPERFAMILY SSF50715 11 178 1.74E-48 T 16-09-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 177 1.1E-41 T 16-09-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 PANTHER PTHR33284 1 200 2.6E-50 T 16-09-2016 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 Gene3D G3DSA:2.170.120.20 96 185 6.3E-23 T 16-09-2016 IPR020057 Ribosomal protein L25, beta domain Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 25.929 T 16-09-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spa2297_RS13560 c196cc25b24eb8e1ee440c4520ccd6e8 200 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 179 2.5E-20 T 16-09-2016 IPR020057 Ribosomal protein L25, beta domain Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 SUPERFAMILY SSF52540 3 233 3.41E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 PANTHER PTHR24220 6 239 2.1E-104 T 16-09-2016 Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 SMART SM00382 29 228 5.5E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 Pfam PF00005 ABC transporter 20 163 7.6E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 4.1E-8 T 16-09-2016 IPR025302 Domain of unknown function DUF4162 Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 6.5E-109 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 Gene3D G3DSA:3.40.50.300 3 233 3.1E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20985 928236e78a97d8e4ecbbcf753e41f170 337 PANTHER PTHR24220:SF0 6 239 2.1E-104 T 16-09-2016 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 PANTHER PTHR21327:SF6 1 429 7.6E-246 T 16-09-2016 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 SUPERFAMILY SSF55821 16 218 1.51E-79 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 SUPERFAMILY SSF142695 222 393 6.28E-69 T 16-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 22 215 1.2E-81 T 16-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 226 414 7.5E-74 T 16-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Gene3D G3DSA:3.90.870.10 15 228 1.4E-93 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 17 413 53.32 T 16-09-2016 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 PIRSF PIRSF001259 17 423 3.3E-173 T 16-09-2016 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 221 417 40.464 T 16-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 PANTHER PTHR21327 1 429 7.6E-246 T 16-09-2016 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Pfam PF00925 GTP cyclohydrolase II 225 390 2.3E-72 T 16-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 216 4.7E-71 T 16-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS05425 a42ce978f4f0e6440e5e0abd0d563350 429 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 16 220 37.408 T 16-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 2.3E-71 T 16-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 SUPERFAMILY SSF52540 10 151 2.3E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 PANTHER PTHR11088 1 288 1.0E-107 T 16-09-2016 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 Pfam PF01715 IPP transferase 43 285 5.8E-71 T 16-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 307 26.861 T 16-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 Gene3D G3DSA:1.10.287.890 201 282 9.6E-27 T 16-09-2016 Spa2297_RS24510 5e646a3602fd20b604b94aa26cb8f276 312 Gene3D G3DSA:3.40.50.300 8 176 5.7E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 SMART SM00382 249 448 0.0011 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 PANTHER PTHR30153 41 490 2.0E-205 T 16-09-2016 Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 SUPERFAMILY SSF52540 230 481 5.89E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 SUPERFAMILY SSF48024 55 166 9.68E-38 T 16-09-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 Pfam PF03796 DnaB-like helicase C terminal domain 232 487 2.3E-108 T 16-09-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 Gene3D G3DSA:1.10.860.10 57 159 1.6E-40 T 16-09-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 Pfam PF00772 DnaB-like helicase N terminal domain 57 158 8.0E-36 T 16-09-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 57 490 5.6E-167 T 16-09-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 Spa2297_RS16415 7763ec4e6592e211dec00580c8b39b8c 492 Gene3D G3DSA:3.40.50.300 217 491 7.9E-119 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16355 9016908254e4bf7442a3dd3385b46ff6 105 PANTHER PTHR36114 1 105 1.8E-50 T 16-09-2016 Spa2297_RS16355 9016908254e4bf7442a3dd3385b46ff6 105 Gene3D G3DSA:2.60.120.10 2 104 1.9E-23 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS16355 9016908254e4bf7442a3dd3385b46ff6 105 SUPERFAMILY SSF51182 17 103 1.02E-20 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS16355 9016908254e4bf7442a3dd3385b46ff6 105 PANTHER PTHR36114:SF3 1 105 1.8E-50 T 16-09-2016 Spa2297_RS16355 9016908254e4bf7442a3dd3385b46ff6 105 Pfam PF07883 Cupin domain 33 100 9.4E-16 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS14565 10d81b6110ca4d954fcf7749f5a64886 274 PANTHER PTHR30294 5 274 1.4E-126 T 16-09-2016 Spa2297_RS14565 10d81b6110ca4d954fcf7749f5a64886 274 PIRSF PIRSF006648 2 274 1.5E-63 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14565 10d81b6110ca4d954fcf7749f5a64886 274 Pfam PF01061 ABC-2 type transporter 25 229 5.9E-29 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS14565 10d81b6110ca4d954fcf7749f5a64886 274 PANTHER PTHR30294:SF24 5 274 1.4E-126 T 16-09-2016 Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 SUPERFAMILY SSF89360 14 108 3.14E-28 T 16-09-2016 IPR000361 FeS cluster biogenesis Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 14 115 8.9E-20 T 16-09-2016 IPR000361 FeS cluster biogenesis Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 16-09-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 Gene3D G3DSA:2.60.300.12 14 108 1.3E-28 T 16-09-2016 IPR000361 FeS cluster biogenesis Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 PANTHER PTHR10072 14 118 5.9E-40 T 16-09-2016 Spa2297_RS08915 4cdb1bba10ee03894cee0e4705f66133 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 2.7E-36 T 16-09-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 PANTHER PTHR11358:SF26 1 323 1.5E-115 T 16-09-2016 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 Pfam PF00491 Arginase family 37 308 5.2E-90 T 16-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 SUPERFAMILY SSF52768 17 312 7.02E-99 T 16-09-2016 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 Gene3D G3DSA:3.40.800.10 12 314 5.1E-117 T 16-09-2016 IPR023696 Ureohydrolase domain Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 PANTHER PTHR11358 1 323 1.5E-115 T 16-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 TIGRFAM TIGR01230 agmatinase: agmatinase 36 309 2.0E-69 T 16-09-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 ProSitePatterns PS01053 Arginase family signature. 240 261 - T 16-09-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 PIRSF PIRSF036979 14 316 6.1E-109 T 16-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 PRINTS PR00116 Arginase signature 237 266 1.6E-14 T 16-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 Spa2297_RS11715 8ba4f0d82368e6921e3db6bc894284fb 323 PRINTS PR00116 Arginase signature 124 139 1.6E-14 T 16-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 Spa2297_RS22460 c983ee039f0638a677a75d57efd0b56e 89 SUPERFAMILY SSF47336 10 85 6.28E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS22460 c983ee039f0638a677a75d57efd0b56e 89 Gene3D G3DSA:1.10.1200.10 6 86 1.5E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS22460 c983ee039f0638a677a75d57efd0b56e 89 Pfam PF00550 Phosphopantetheine attachment site 13 81 1.8E-9 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS22460 c983ee039f0638a677a75d57efd0b56e 89 ProSitePatterns PS00012 Phosphopantetheine attachment site. 41 56 - T 16-09-2016 IPR006162 Phosphopantetheine attachment site Spa2297_RS00290 bb92b1903ae444204037b1f3192d064f 356 Pfam PF04616 Glycosyl hydrolases family 43 39 287 3.3E-32 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS00290 bb92b1903ae444204037b1f3192d064f 356 PANTHER PTHR22925 41 330 3.6E-81 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS00290 bb92b1903ae444204037b1f3192d064f 356 Gene3D G3DSA:2.115.10.20 40 333 8.9E-58 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00290 bb92b1903ae444204037b1f3192d064f 356 SUPERFAMILY SSF75005 37 292 7.99E-42 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00290 bb92b1903ae444204037b1f3192d064f 356 PANTHER PTHR22925:SF12 41 330 3.6E-81 T 16-09-2016 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 SMART SM00421 898 955 2.8E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 SUPERFAMILY SSF46894 891 956 1.6E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 SUPERFAMILY SSF52540 32 270 7.59E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Gene3D G3DSA:1.25.40.10 625 869 1.0E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 SMART SM00382 50 216 2.2E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Gene3D G3DSA:1.10.10.10 880 956 1.1E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 SUPERFAMILY SSF48452 635 775 1.87E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Pfam PF13191 AAA ATPase domain 45 187 6.7E-20 T 16-09-2016 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Pfam PF00196 Bacterial regulatory proteins, luxR family 901 955 2.9E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 PANTHER PTHR16305 30 786 7.8E-72 T 16-09-2016 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Gene3D G3DSA:3.40.50.300 32 120 8.1E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 Gene3D G3DSA:3.40.50.300 155 170 8.1E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 915 931 5.5E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 931 943 5.5E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26255 b55ec9837077d691b102fe3adf1d5e3e 961 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 901 915 5.5E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 Gene3D G3DSA:3.40.350.10 3 136 2.8E-12 T 16-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 SUPERFAMILY SSF55920 138 366 2.22E-57 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 SUPERFAMILY SSF53092 5 136 4.71E-19 T 16-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 PANTHER PTHR10804:SF109 119 366 3.9E-125 T 16-09-2016 Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 Pfam PF00557 Metallopeptidase family M24 146 348 5.9E-44 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 PANTHER PTHR10804 119 366 3.9E-125 T 16-09-2016 Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 1.4E-12 T 16-09-2016 IPR000587 Creatinase, N-terminal GO:0016787 Spa2297_RS05630 f387a33e6192541b60526774adc48202 368 Gene3D G3DSA:3.90.230.10 138 365 5.1E-56 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS03745 d4570c6def92e702924383b40b69f4e5 343 Gene3D G3DSA:2.130.10.10 9 342 2.4E-92 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS03745 d4570c6def92e702924383b40b69f4e5 343 SUPERFAMILY SSF51004 30 324 3.27E-39 T 16-09-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain Spa2297_RS03745 d4570c6def92e702924383b40b69f4e5 343 PANTHER PTHR30344 6 342 7.5E-98 T 16-09-2016 Spa2297_RS03745 d4570c6def92e702924383b40b69f4e5 343 Pfam PF10282 Lactonase, 7-bladed beta-propeller 10 342 2.0E-91 T 16-09-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 Spa2297_RS03745 d4570c6def92e702924383b40b69f4e5 343 PANTHER PTHR30344:SF1 6 342 7.5E-98 T 16-09-2016 Spa2297_RS13660 e0319e59f3c4c4e4eb801720ac1e8c5c 559 PANTHER PTHR11819 16 538 1.4E-185 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS13660 e0319e59f3c4c4e4eb801720ac1e8c5c 559 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 456 3.2E-68 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS13660 e0319e59f3c4c4e4eb801720ac1e8c5c 559 Pfam PF00474 Sodium:solute symporter family 47 456 1.8E-49 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS13660 e0319e59f3c4c4e4eb801720ac1e8c5c 559 PANTHER PTHR11819:SF7 16 538 1.4E-185 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.20.20.80 498 557 9.3E-97 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.20.20.80 76 337 9.3E-97 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.20.20.80 454 455 9.3E-97 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.20.20.80 371 394 9.3E-97 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SMART SM00495 739 784 4.1E-13 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Pfam PF06483 Chitinase C 540 708 2.2E-79 T 16-09-2016 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902|UniPathway: UPA00349 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Pfam PF02839 Carbohydrate binding domain 739 781 4.4E-11 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SUPERFAMILY SSF51055 737 787 8.04E-14 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SMART SM00636 78 531 3.9E-131 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 ProSitePatterns PS01095 Chitinases family 18 active site. 230 238 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.10.50.10 478 497 2.4E-17 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:3.10.50.10 395 438 2.4E-17 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Gene3D G3DSA:2.10.10.20 737 784 5.1E-18 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177 714 785 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177 155 344 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SUPERFAMILY SSF51445 72 388 7.8E-80 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SUPERFAMILY SSF51445 503 533 7.8E-80 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177:SF215 155 344 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 Pfam PF00704 Glycosyl hydrolases family 18 79 531 2.3E-82 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 SUPERFAMILY SSF54556 388 501 4.4E-14 T 16-09-2016 IPR029070 Chitinase insertion domain Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177 361 440 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177 480 563 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177:SF215 714 785 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177:SF215 361 440 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177:SF215 480 563 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177 72 131 1.8E-204 T 16-09-2016 Spa2297_RS05440 88a570b1bfbf970ced4d42792c86e439 787 PANTHER PTHR11177:SF215 72 131 1.8E-204 T 16-09-2016 Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PANTHER PTHR24322 152 182 6.3E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PANTHER PTHR24322 6 126 6.3E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.1E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.1E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.1E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.1E-24 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 Gene3D G3DSA:3.40.50.720 1 225 1.3E-54 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PANTHER PTHR24322:SF622 6 126 6.3E-43 T 16-09-2016 Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 Pfam PF00106 short chain dehydrogenase 3 189 1.8E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.5E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 PANTHER PTHR24322:SF622 152 182 6.3E-43 T 16-09-2016 Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS00540 747371390fdbf6fa8c07e39857e95f40 228 SUPERFAMILY SSF51735 3 211 2.47E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23655 e82ca50b0ef83382dfc049c009109aa1 134 PANTHER PTHR33204:SF7 9 131 6.6E-63 T 16-09-2016 Spa2297_RS23655 e82ca50b0ef83382dfc049c009109aa1 134 SUPERFAMILY SSF46785 16 130 5.46E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23655 e82ca50b0ef83382dfc049c009109aa1 134 PANTHER PTHR33204 9 131 6.6E-63 T 16-09-2016 Spa2297_RS23655 e82ca50b0ef83382dfc049c009109aa1 134 Pfam PF01638 HxlR-like helix-turn-helix 31 112 7.7E-24 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS23655 e82ca50b0ef83382dfc049c009109aa1 134 Gene3D G3DSA:1.10.10.10 10 129 3.9E-39 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01210 2bb8de106bd4e8775c8a198216b16cc4 312 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 50 300 1.4E-59 T 16-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 Spa2297_RS01210 2bb8de106bd4e8775c8a198216b16cc4 312 Gene3D G3DSA:3.60.130.10 40 312 7.3E-88 T 16-09-2016 Spa2297_RS01210 2bb8de106bd4e8775c8a198216b16cc4 312 PANTHER PTHR30468 53 312 5.5E-82 T 16-09-2016 Spa2297_RS01210 2bb8de106bd4e8775c8a198216b16cc4 312 SUPERFAMILY SSF51197 44 312 6.87E-86 T 16-09-2016 Spa2297_RS01210 2bb8de106bd4e8775c8a198216b16cc4 312 PANTHER PTHR30468:SF2 53 312 5.5E-82 T 16-09-2016 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 Gene3D G3DSA:1.10.10.60 9 72 2.9E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 SUPERFAMILY SSF46689 9 83 1.54E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.4E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 PANTHER PTHR30055:SF34 3 201 6.8E-76 T 16-09-2016 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 SUPERFAMILY SSF48498 85 200 2.38E-25 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 Gene3D G3DSA:1.10.357.10 75 201 8.2E-38 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00545 24329bdf72236a0485cce9dd3ada9beb 202 PANTHER PTHR30055 3 201 6.8E-76 T 16-09-2016 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 49 1.1E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 PANTHER PTHR30055:SF78 6 157 8.7E-22 T 16-09-2016 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 Gene3D G3DSA:1.10.10.60 5 53 7.0E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 SUPERFAMILY SSF48498 76 166 1.27E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 Pfam PF13305 WHG domain 80 149 6.7E-8 T 16-09-2016 IPR025996 WHG domain Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 SUPERFAMILY SSF46689 4 69 7.98E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 PANTHER PTHR30055 6 157 8.7E-22 T 16-09-2016 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 Gene3D G3DSA:1.10.357.10 54 167 3.0E-17 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15175 6221687f97b1cc1afcab70f569770aeb 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 PANTHER PTHR10566:SF10 60 434 6.7E-119 T 16-09-2016 Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 SUPERFAMILY SSF56112 208 348 7.72E-24 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 SUPERFAMILY SSF56112 118 168 7.72E-24 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 PANTHER PTHR10566 60 434 6.7E-119 T 16-09-2016 Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 Gene3D G3DSA:3.90.1200.10 269 323 6.7E-7 T 16-09-2016 Spa2297_RS04660 6bcd1ecf499d272e191b8d2255c9b7ff 525 Pfam PF03109 ABC1 family 122 241 1.5E-23 T 16-09-2016 IPR004147 UbiB domain Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Gene3D G3DSA:1.10.601.10 30 169 2.0E-55 T 16-09-2016 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Gene3D G3DSA:1.10.10.10 263 328 2.1E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Pfam PF00140 Sigma-70 factor, region 1.2 34 67 4.1E-11 T 16-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PANTHER PTHR30603 29 325 1.5E-130 T 16-09-2016 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 SUPERFAMILY SSF88659 231 325 1.2E-23 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Gene3D G3DSA:1.10.10.10 170 223 4.9E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 124 137 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Pfam PF04539 Sigma-70 region 3 179 255 3.2E-25 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Pfam PF04542 Sigma-70 region 2 100 170 1.6E-20 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PANTHER PTHR30603:SF0 29 325 1.5E-130 T 16-09-2016 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 Pfam PF04545 Sigma-70, region 4 269 321 3.1E-15 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 321 1.5E-33 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PRINTS PR00046 Major sigma-70 factor signature 293 308 2.9E-25 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PRINTS PR00046 Major sigma-70 factor signature 148 156 2.9E-25 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PRINTS PR00046 Major sigma-70 factor signature 308 319 2.9E-25 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PRINTS PR00046 Major sigma-70 factor signature 272 284 2.9E-25 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 PRINTS PR00046 Major sigma-70 factor signature 124 137 2.9E-25 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 293 319 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 SUPERFAMILY SSF88659 173 246 5.89E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13940 fcfc207f8c1ac0e733d20d864bd5df60 332 SUPERFAMILY SSF88946 34 170 1.07E-48 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 SUPERFAMILY SSF103473 21 470 1.2E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 20 470 2.4E-100 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 Gene3D G3DSA:1.20.1250.20 271 469 1.5E-21 T 16-09-2016 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 Gene3D G3DSA:1.20.1250.20 29 227 3.2E-23 T 16-09-2016 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PRINTS PR00171 Sugar transporter signature 33 43 3.6E-21 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PRINTS PR00171 Sugar transporter signature 376 397 3.6E-21 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PRINTS PR00171 Sugar transporter signature 399 411 3.6E-21 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PRINTS PR00171 Sugar transporter signature 283 293 3.6E-21 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PRINTS PR00171 Sugar transporter signature 116 135 3.6E-21 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PANTHER PTHR23503:SF24 6 470 0.0 T 16-09-2016 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 PANTHER PTHR23503 6 470 0.0 T 16-09-2016 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 Pfam PF00083 Sugar (and other) transporter 26 470 2.4E-105 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS23680 4670ba6bec8ee8055f39971a9175c391 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 327 344 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 PANTHER PTHR11654 17 231 1.9E-163 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 Gene3D G3DSA:1.20.1250.20 39 204 3.7E-10 T 16-09-2016 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 16-09-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 SUPERFAMILY SSF103473 17 254 6.41E-24 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 Pfam PF00854 POT family 96 456 4.7E-61 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 SUPERFAMILY SSF103473 238 491 7.19E-8 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 PANTHER PTHR11654:SF119 17 231 1.9E-163 T 16-09-2016 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 494 8.2E-227 T 16-09-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 PANTHER PTHR11654:SF119 271 457 1.9E-163 T 16-09-2016 Spa2297_RS13280 1e2ba9e44735bff1eb682208f3f84ece 498 PANTHER PTHR11654 271 457 1.9E-163 T 16-09-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS17670 867badb8f5fe66b65272a7c2d11ba3ef 309 PANTHER PTHR12358 3 140 2.6E-30 T 16-09-2016 Spa2297_RS17670 867badb8f5fe66b65272a7c2d11ba3ef 309 PANTHER PTHR12358:SF44 3 140 2.6E-30 T 16-09-2016 Spa2297_RS17670 867badb8f5fe66b65272a7c2d11ba3ef 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 21 139 9.3E-6 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS17670 867badb8f5fe66b65272a7c2d11ba3ef 309 SUPERFAMILY SSF111331 20 221 1.33E-13 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 PANTHER PTHR32196 51 335 2.8E-80 T 16-09-2016 Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 PANTHER PTHR32196:SF9 51 335 2.8E-80 T 16-09-2016 Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 Gene3D G3DSA:3.40.50.2300 49 172 3.7E-30 T 16-09-2016 Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 Pfam PF13407 Periplasmic binding protein domain 55 312 8.5E-47 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 SUPERFAMILY SSF53822 51 342 1.01E-64 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS27355 f7307d0c6b7bd5f7da5798fb8c3b9ab1 347 Gene3D G3DSA:3.40.50.2300 173 342 8.7E-38 T 16-09-2016 Spa2297_RS20105 da68814245447469ece34c9c76444b47 112 Pfam PF02467 Transcription factor WhiB 17 87 6.7E-25 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS20105 da68814245447469ece34c9c76444b47 112 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 6 94 17.254 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS20105 da68814245447469ece34c9c76444b47 112 PANTHER PTHR38839:SF1 1 104 3.1E-64 T 16-09-2016 Spa2297_RS20105 da68814245447469ece34c9c76444b47 112 PANTHER PTHR38839 1 104 3.1E-64 T 16-09-2016 Spa2297_RS02940 40a12ac8e98b591028965fbe3641a2fd 85 Gene3D G3DSA:1.10.1200.10 3 77 4.9E-13 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02940 40a12ac8e98b591028965fbe3641a2fd 85 Pfam PF00550 Phosphopantetheine attachment site 3 70 1.3E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02940 40a12ac8e98b591028965fbe3641a2fd 85 SUPERFAMILY SSF47336 3 76 1.57E-11 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS31330 4c58a00863c59f988468f7dbe53def24 112 SUPERFAMILY SSF52091 1 90 2.16E-15 T 16-09-2016 IPR002645 STAS domain Spa2297_RS31330 4c58a00863c59f988468f7dbe53def24 112 Gene3D G3DSA:3.30.750.24 1 90 2.3E-16 T 16-09-2016 IPR002645 STAS domain Spa2297_RS31330 4c58a00863c59f988468f7dbe53def24 112 Pfam PF13466 STAS domain 18 90 3.6E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 PIRSF PIRSF036625 1 247 4.0E-94 T 16-09-2016 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 Gene3D G3DSA:3.30.450.40 26 178 8.3E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 Gene3D G3DSA:1.10.10.10 182 238 3.0E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 SMART SM00065 40 185 2.8E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 SUPERFAMILY SSF55781 42 186 8.51E-12 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 SUPERFAMILY SSF52172 173 235 9.94E-7 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 Pfam PF03861 ANTAR domain 182 235 4.9E-18 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 Pfam PF13185 GAF domain 40 176 2.7E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16015 75c60027851c36c3e22f736e308460c6 249 SMART SM01012 180 235 7.9E-20 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 Pfam PF01433 Peptidase family M1 18 383 4.5E-67 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 Pfam PF11838 ERAP1-like C-terminal domain 512 822 7.5E-52 T 16-09-2016 IPR024571 ERAP1-like C-terminal domain Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PANTHER PTHR11533 645 692 2.6E-156 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 SUPERFAMILY SSF63737 2 192 7.45E-39 T 16-09-2016 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PANTHER PTHR11533 20 627 2.6E-156 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 829 0.0 T 16-09-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 Gene3D G3DSA:1.10.390.10 303 451 9.4E-39 T 16-09-2016 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PANTHER PTHR11533:SF190 645 692 2.6E-156 T 16-09-2016 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 256 266 2.1E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 2.1E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 321 2.1E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 2.1E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 305 2.1E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 SUPERFAMILY SSF55486 199 449 1.05E-69 T 16-09-2016 Spa2297_RS08210 8402fc88d6633afabf64375dc8c4ff4f 832 PANTHER PTHR11533:SF190 20 627 2.6E-156 T 16-09-2016 Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 Gene3D G3DSA:3.10.180.10 138 250 1.7E-28 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 Gene3D G3DSA:3.10.180.10 9 122 4.0E-34 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 SUPERFAMILY SSF54593 138 249 1.06E-17 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 PANTHER PTHR33993 6 255 1.3E-111 T 16-09-2016 Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 PANTHER PTHR33993:SF3 6 255 1.3E-111 T 16-09-2016 Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 117 1.4E-8 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS02270 b127adbb4d1ca72e19b0d0b4effd4900 265 SUPERFAMILY SSF54593 16 124 1.48E-20 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 Gene3D G3DSA:1.20.1560.10 26 77 6.2E-87 T 16-09-2016 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 Gene3D G3DSA:1.20.1560.10 109 384 6.2E-87 T 16-09-2016 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 Pfam PF00005 ABC transporter 414 563 7.2E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 Gene3D G3DSA:3.40.50.300 397 627 1.2E-77 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 Pfam PF00664 ABC transporter transmembrane region 42 351 2.4E-58 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 PANTHER PTHR24221:SF271 16 78 0.0 T 16-09-2016 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 PANTHER PTHR24221:SF271 116 642 0.0 T 16-09-2016 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 SMART SM00382 422 609 1.5E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 ProSitePatterns PS00211 ABC transporters family signature. 535 549 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 SUPERFAMILY SSF52540 391 634 5.76E-88 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 SUPERFAMILY SSF90123 26 70 3.4E-84 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 SUPERFAMILY SSF90123 111 384 3.4E-84 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 PANTHER PTHR24221 16 78 0.0 T 16-09-2016 Spa2297_RS10395 dfe9118d845262e4ae8b64854c51ed06 642 PANTHER PTHR24221 116 642 0.0 T 16-09-2016 Spa2297_RS26335 9ce0a145dcc9c80156c045146edbcb7b 470 TIGRFAM TIGR03173 pbuX: xanthine permease 43 454 7.9E-144 T 16-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 Spa2297_RS26335 9ce0a145dcc9c80156c045146edbcb7b 470 PANTHER PTHR11119 30 462 4.2E-114 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS26335 9ce0a145dcc9c80156c045146edbcb7b 470 Pfam PF00860 Permease family 39 421 6.1E-91 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS26335 9ce0a145dcc9c80156c045146edbcb7b 470 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 369 389 - T 16-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS26335 9ce0a145dcc9c80156c045146edbcb7b 470 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 39 451 6.0E-106 T 16-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 Gene3D G3DSA:3.40.1350.10 10 119 1.3E-34 T 16-09-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 SUPERFAMILY SSF52980 7 102 1.25E-18 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 Pfam PF02021 Uncharacterised protein family UPF0102 11 103 4.1E-26 T 16-09-2016 IPR003509 Uncharacterised protein family UPF0102 Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 PANTHER PTHR34039 1 119 2.0E-37 T 16-09-2016 Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 116 21.259 T 16-09-2016 IPR003509 Uncharacterised protein family UPF0102 Spa2297_RS23790 60518619d1bff2ef0ac679f3cbcd6b41 120 PANTHER PTHR34039:SF1 1 119 2.0E-37 T 16-09-2016 Spa2297_RS02205 8fde784723d980434adaa1ed9f02d19d 117 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 18 81 1.1E-12 T 16-09-2016 IPR001607 Zinc finger, UBP-type GO:0008270 Spa2297_RS02205 8fde784723d980434adaa1ed9f02d19d 117 Gene3D G3DSA:3.30.40.10 11 81 4.7E-22 T 16-09-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type Spa2297_RS02205 8fde784723d980434adaa1ed9f02d19d 117 SUPERFAMILY SSF57850 11 82 5.06E-26 T 16-09-2016 Spa2297_RS02205 8fde784723d980434adaa1ed9f02d19d 117 PANTHER PTHR24007 1 117 7.0E-30 T 16-09-2016 Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 SMART SM00345 12 71 3.9E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 SUPERFAMILY SSF64288 59 248 7.07E-23 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 4.1E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 SUPERFAMILY SSF46785 4 82 5.14E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 SMART SM00866 98 242 1.2E-12 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 Gene3D G3DSA:3.40.1410.10 73 245 4.3E-54 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 Gene3D G3DSA:1.10.10.10 8 72 1.9E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21500 e94f5d65f3ed50c4b6dc511d6cb11fbc 250 Pfam PF07702 UTRA domain 110 242 4.4E-13 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 SUPERFAMILY SSF46785 62 132 2.19E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 Pfam PF07729 FCD domain 157 279 1.6E-22 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 PANTHER PTHR11751:SF436 155 173 1.8E-21 T 16-09-2016 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 SMART SM00895 157 281 5.1E-22 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 PANTHER PTHR11751 69 135 1.8E-21 T 16-09-2016 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 PANTHER PTHR11751:SF436 69 135 1.8E-21 T 16-09-2016 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 Gene3D G3DSA:1.10.10.10 60 130 8.1E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 SMART SM00345 70 128 1.1E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 Gene3D G3DSA:1.20.120.530 154 280 1.4E-25 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 Pfam PF00392 Bacterial regulatory proteins, gntR family 69 128 2.3E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 SUPERFAMILY SSF48008 154 280 1.65E-25 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS24650 681b29ea66b29a2802a92b51b070cd1e 295 PANTHER PTHR11751 155 173 1.8E-21 T 16-09-2016 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 Gene3D G3DSA:3.30.70.120 1 112 2.2E-45 T 16-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PRINTS PR00340 P-II protein signature 2 17 1.0E-36 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PRINTS PR00340 P-II protein signature 52 75 1.0E-36 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PRINTS PR00340 P-II protein signature 23 41 1.0E-36 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PRINTS PR00340 P-II protein signature 83 103 1.0E-36 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PANTHER PTHR30115 1 112 4.6E-57 T 16-09-2016 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 SMART SM00938 4 105 1.2E-56 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 16-09-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.5E-39 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 SUPERFAMILY SSF54913 1 112 1.62E-41 T 16-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spa2297_RS23715 e1bd16b81a72c9952d89560cdfbd0198 112 PIRSF PIRSF039144 1 112 6.6E-50 T 16-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spa2297_RS13170 f6faacc0e5f4bc4241f986a90b80e5d1 254 SUPERFAMILY SSF56801 3 250 1.31E-22 T 16-09-2016 Spa2297_RS13170 f6faacc0e5f4bc4241f986a90b80e5d1 254 Gene3D G3DSA:3.40.50.980 7 90 4.8E-9 T 16-09-2016 Spa2297_RS13170 f6faacc0e5f4bc4241f986a90b80e5d1 254 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 249 2.2E-88 T 16-09-2016 IPR017523 Conserved hypothetical protein CHP03089 Spa2297_RS13170 f6faacc0e5f4bc4241f986a90b80e5d1 254 Pfam PF00501 AMP-binding enzyme 18 96 3.4E-8 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 PANTHER PTHR24220:SF491 23 278 2.9E-130 T 16-09-2016 Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 Gene3D G3DSA:3.40.50.300 19 264 8.9E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 PANTHER PTHR24220 23 278 2.9E-130 T 16-09-2016 Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 245 267 6.0E-6 T 16-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 SMART SM00382 46 236 3.4E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 SUPERFAMILY SSF52540 13 267 7.66E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08175 f863602318c9eff4b0e10acadfd8accf 304 Pfam PF00005 ABC transporter 37 197 2.3E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS05335 b6b9bded2768951ac5b4fc96ec395a5e 190 PANTHER PTHR35335:SF1 7 190 2.2E-37 T 16-09-2016 Spa2297_RS05335 b6b9bded2768951ac5b4fc96ec395a5e 190 PANTHER PTHR35335 7 190 2.2E-37 T 16-09-2016 Spa2297_RS05335 b6b9bded2768951ac5b4fc96ec395a5e 190 Pfam PF04186 FxsA cytoplasmic membrane protein 26 137 3.4E-29 T 16-09-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 47 315 2.2E-62 T 16-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 PANTHER PTHR30177 41 319 9.8E-117 T 16-09-2016 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 PANTHER PTHR30177:SF9 41 319 9.8E-117 T 16-09-2016 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 SUPERFAMILY SSF53850 47 319 9.23E-61 T 16-09-2016 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 Gene3D G3DSA:3.40.190.10 46 149 4.0E-52 T 16-09-2016 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 Gene3D G3DSA:3.40.190.10 263 319 4.0E-52 T 16-09-2016 Spa2297_RS12555 8c7390f22c24757e0a288e2ad6e2c200 322 Gene3D G3DSA:3.40.190.120 150 257 6.0E-33 T 16-09-2016 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 660 4.2E-180 T 16-09-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 657 2.6E-94 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 SUPERFAMILY SSF56601 213 458 1.19E-87 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 SUPERFAMILY SSF56601 515 663 1.19E-87 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 PANTHER PTHR30627 1 474 3.8E-223 T 16-09-2016 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 246 2.8E-39 T 16-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 PANTHER PTHR30627:SF2 509 694 3.8E-223 T 16-09-2016 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 PANTHER PTHR30627:SF2 1 474 3.8E-223 T 16-09-2016 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 Gene3D G3DSA:3.40.710.10 510 660 9.8E-95 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 Gene3D G3DSA:3.40.710.10 261 472 9.8E-95 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 SUPERFAMILY SSF56519 53 261 9.03E-36 T 16-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 Gene3D G3DSA:3.90.1310.10 137 259 6.2E-30 T 16-09-2016 Spa2297_RS11020 884575a9cd01ebda9a3ddacd7e5fe2ea 763 PANTHER PTHR30627 509 694 3.8E-223 T 16-09-2016 Spa2297_RS07665 f747f90edc133abe73230c25fd25af02 65 SUPERFAMILY SSF57938 3 54 8.37E-5 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS07665 f747f90edc133abe73230c25fd25af02 65 Gene3D G3DSA:2.10.230.10 9 54 4.9E-5 T 16-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 PANTHER PTHR17224 9 199 5.6E-75 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 23 36 - T 16-09-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 SUPERFAMILY SSF53178 10 199 2.88E-63 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 122 132 - T 16-09-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 Pfam PF01195 Peptidyl-tRNA hydrolase 12 197 4.1E-51 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 10 192 32.929 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 12 200 2.1E-53 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS13565 99a8848d46b0dc10aadc8955c488d8d1 200 Gene3D G3DSA:3.40.50.1470 6 199 4.4E-69 T 16-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spa2297_RS15065 943ff6638989ea3a420a20bb8b5a4eb6 544 Pfam PF07681 DoxX 209 310 8.2E-11 T 16-09-2016 IPR032808 DoxX family Spa2297_RS15065 943ff6638989ea3a420a20bb8b5a4eb6 544 PANTHER PTHR39157 1 544 2.5E-113 T 16-09-2016 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 Gene3D G3DSA:2.40.150.20 2 122 5.1E-53 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.207 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.6E-53 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 16-09-2016 IPR019972 Ribosomal protein L14P, conserved site Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 SMART SM01374 1 122 1.8E-86 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.4E-57 T 16-09-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 PANTHER PTHR11761 2 122 1.1E-76 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19845 6fdc75b69b8eaf3451d2b3d790a1f93c 122 SUPERFAMILY SSF50193 2 122 5.36E-50 T 16-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spa2297_RS24955 0ca0dd45dc745d31f4b7281b99f79a79 262 PANTHER PTHR31360 31 262 9.4E-93 T 16-09-2016 Spa2297_RS24955 0ca0dd45dc745d31f4b7281b99f79a79 262 Pfam PF06884 Protein of unknown function (DUF1264) 70 233 3.5E-67 T 16-09-2016 IPR010686 Protein of unknown function DUF1264 Spa2297_RS24955 0ca0dd45dc745d31f4b7281b99f79a79 262 PANTHER PTHR31360:SF0 31 262 9.4E-93 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF55008 18 85 4.19E-16 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 679 704 8.2E-8 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 648 664 8.2E-8 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 620 636 8.2E-8 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF81665 697 722 4.71E-12 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF81665 224 258 4.71E-12 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF81665 355 448 4.71E-12 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 ProSitePatterns PS01047 Heavy-metal-associated domain. 26 54 - T 16-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 173 750 1.9E-178 T 16-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Pfam PF00702 haloacid dehalogenase-like hydrolase 450 662 2.3E-45 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PANTHER PTHR24093:SF50 1 753 1.6E-232 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Gene3D G3DSA:2.70.150.10 222 355 7.8E-26 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Gene3D G3DSA:3.40.50.1000 426 469 2.3E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Gene3D G3DSA:3.40.50.1000 576 716 2.3E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 222 750 1.2E-116 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Gene3D G3DSA:3.30.70.100 18 84 7.0E-19 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 228 729 9.1E-82 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PANTHER PTHR24093 1 753 1.6E-232 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF56784 511 748 8.88E-55 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF56784 452 472 8.88E-55 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Pfam PF00403 Heavy-metal-associated domain 25 82 3.5E-11 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Pfam PF00122 E1-E2 ATPase 227 445 2.2E-63 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 SUPERFAMILY SSF81653 260 354 5.62E-23 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 ProSitePatterns PS01229 Hypothetical cof family signature 2. 648 670 - T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 Gene3D G3DSA:3.40.1110.10 470 575 6.2E-21 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 218 751 6.0E-154 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 456 462 - T 16-09-2016 IPR018303 P-type ATPase, phosphorylation site Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 605 5.4E-24 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 454 468 5.4E-24 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 683 5.4E-24 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 573 584 5.4E-24 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 5.4E-24 T 16-09-2016 Spa2297_RS11560 d669fb276808cdaf0c5908b6afd0a1a1 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 667 5.4E-24 T 16-09-2016 Spa2297_RS30770 a9056dd63deffcf478e07e97b93e4be3 140 Pfam PF03994 Domain of Unknown Function (DUF350) 85 139 2.7E-14 T 16-09-2016 IPR007140 Protein of unknown function DUF350 Spa2297_RS30770 a9056dd63deffcf478e07e97b93e4be3 140 Pfam PF03994 Domain of Unknown Function (DUF350) 14 68 4.8E-15 T 16-09-2016 IPR007140 Protein of unknown function DUF350 Spa2297_RS06295 1a369d2f615888762d9d45039aaf9342 138 PANTHER PTHR36221 9 138 1.6E-38 T 16-09-2016 Spa2297_RS06295 1a369d2f615888762d9d45039aaf9342 138 Pfam PF05331 Protein of unknown function (DUF742) 32 138 5.5E-32 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 Gene3D G3DSA:1.10.10.10 23 96 5.9E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 SUPERFAMILY SSF46785 24 103 1.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 94 9.0E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 SMART SM00866 114 252 9.4E-35 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 SUPERFAMILY SSF64288 82 256 2.04E-46 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 Pfam PF07702 UTRA domain 115 251 9.6E-38 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PANTHER PTHR11751:SF10 217 239 1.4E-23 T 16-09-2016 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PANTHER PTHR11751:SF10 25 97 1.4E-23 T 16-09-2016 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PANTHER PTHR11751 217 239 1.4E-23 T 16-09-2016 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PANTHER PTHR11751 25 97 1.4E-23 T 16-09-2016 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 Gene3D G3DSA:3.40.1410.10 97 254 3.5E-50 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 7.9E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 7.9E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS28455 a52b29d318bfa901a88281191c142a64 261 SMART SM00345 35 94 5.4E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PANTHER PTHR13789:SF186 1 368 2.8E-80 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 SUPERFAMILY SSF51905 286 368 9.55E-56 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 SUPERFAMILY SSF51905 3 176 9.55E-56 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PANTHER PTHR13789 1 368 2.8E-80 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 Gene3D G3DSA:3.50.50.60 286 363 3.9E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 Gene3D G3DSA:3.50.50.60 2 181 3.9E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.9E-18 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.9E-18 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 2.9E-18 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 2.9E-18 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 SUPERFAMILY SSF54373 182 290 1.35E-24 T 16-09-2016 Spa2297_RS23955 636b7caf4d3680818fbdf447a3cfd8cb 428 Pfam PF01494 FAD binding domain 2 358 1.0E-20 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Gene3D G3DSA:3.40.50.300 99 383 8.9E-109 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 PANTHER PTHR15184:SF3 1 497 4.5E-277 T 16-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 PANTHER PTHR15184 1 497 4.5E-277 T 16-09-2016 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Gene3D G3DSA:2.40.30.20 5 97 6.4E-28 T 16-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 SUPERFAMILY SSF52540 100 382 4.52E-93 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 16-09-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.0E-239 T 16-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 1.1E-46 T 16-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.162 T 16-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 SUPERFAMILY SSF47917 384 512 1.07E-45 T 16-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 5.3E-67 T 16-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 SUPERFAMILY SSF50615 27 98 9.94E-22 T 16-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 2.6E-14 T 16-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS22690 8d0a1dce70dc71d71be028086f54ba88 529 Gene3D G3DSA:1.20.150.20 384 512 6.9E-51 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 16-09-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 PIRSF PIRSF000171 1 578 1.1E-47 T 16-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Gene3D G3DSA:3.90.700.10 243 349 2.5E-41 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Gene3D G3DSA:3.50.50.60 2 242 9.2E-113 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Gene3D G3DSA:3.50.50.60 350 421 9.2E-113 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 PANTHER PTHR11632:SF5 1 584 0.0 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 4.1E-5 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.1E-5 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Gene3D G3DSA:4.10.80.40 543 580 2.9E-18 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 SUPERFAMILY SSF56425 236 354 1.03E-42 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 1.9E-277 T 16-09-2016 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 PANTHER PTHR11632 1 584 0.0 T 16-09-2016 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Pfam PF00890 FAD binding domain 7 400 3.0E-112 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Gene3D G3DSA:1.20.58.100 429 542 4.4E-42 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 3.7E-246 T 16-09-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 SUPERFAMILY SSF46977 446 584 2.62E-51 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 SUPERFAMILY SSF51905 358 439 1.22E-70 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 SUPERFAMILY SSF51905 2 259 1.22E-70 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20520 0d3db730a5676c7c1da5eacf4c744e3a 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 7.9E-46 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 Pfam PF00121 Triosephosphate isomerase 2 246 5.7E-89 T 16-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 PANTHER PTHR21139 2 249 1.4E-112 T 16-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 1 249 37.145 T 16-09-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 SUPERFAMILY SSF51351 2 248 1.96E-90 T 16-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 16-09-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 2 239 6.9E-56 T 16-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 Spa2297_RS07840 306668bc8da869e68ff6647b331a760a 251 Gene3D G3DSA:3.20.20.70 1 248 4.3E-104 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.6E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.6E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.6E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PANTHER PTHR24322 16 141 6.8E-51 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PANTHER PTHR24322 158 189 6.8E-51 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.5E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 Pfam PF00106 short chain dehydrogenase 15 198 6.1E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 SUPERFAMILY SSF51735 12 246 6.72E-61 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 Gene3D G3DSA:3.40.50.720 12 246 1.7E-64 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02810 f494bdde4a548b074dee15ff2394feb2 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 198 9.8E-5 T 16-09-2016 Spa2297_RS14120 4e76187b07a98e87a8ce3de4619ba766 80 PANTHER PTHR37301 2 79 1.0E-33 T 16-09-2016 Spa2297_RS14120 4e76187b07a98e87a8ce3de4619ba766 80 SUPERFAMILY SSF47413 1 67 3.44E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14120 4e76187b07a98e87a8ce3de4619ba766 80 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 67 1.3E-19 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS14120 4e76187b07a98e87a8ce3de4619ba766 80 Gene3D G3DSA:1.10.260.40 1 66 4.9E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS14120 4e76187b07a98e87a8ce3de4619ba766 80 SMART SM00530 6 62 2.8E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 Pfam PF01926 50S ribosome-binding GTPase 277 395 2.4E-20 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 PANTHER PTHR10229 7 480 1.8E-168 T 16-09-2016 IPR016496 GTPase HflX GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 Gene3D G3DSA:3.40.50.300 275 437 3.5E-38 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 PIRSF PIRSF006809 70 495 3.0E-156 T 16-09-2016 IPR016496 GTPase HflX GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 344 362 2.0E-6 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 297 2.0E-6 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 Pfam PF16360 GTP-binding GTPase Middle Region 186 269 2.4E-28 T 16-09-2016 IPR032305 GTP-binding protein, middle domain Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 SUPERFAMILY SSF52540 276 463 2.52E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 PANTHER PTHR10229:SF0 7 480 1.8E-168 T 16-09-2016 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 Hamap MF_00900 GTPase HflX [hflX]. 99 465 47.366 T 16-09-2016 IPR016496 GTPase HflX GO:0005525 Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 Pfam PF13167 GTP-binding GTPase N-terminal 96 184 9.0E-32 T 16-09-2016 IPR025121 GTPase HflX, N-terminal Spa2297_RS24535 cceba0b9a807dd99634f47c0e5bf4278 497 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 80 435 3.5E-130 T 16-09-2016 IPR016496 GTPase HflX GO:0005525 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 Gene3D G3DSA:3.30.420.40 265 509 1.3E-98 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 PANTHER PTHR10196:SF69 9 512 4.7E-271 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 SUPERFAMILY SSF53067 10 265 1.21E-92 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 Hamap MF_00186 Glycerol kinase [glpK]. 8 508 55.674 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 Gene3D G3DSA:3.30.420.40 8 263 4.4E-109 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 262 1.1E-81 T 16-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 272 461 2.7E-60 T 16-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 PANTHER PTHR10196 9 512 4.7E-271 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 373 393 - T 16-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 PIRSF PIRSF000538 8 512 5.5E-168 T 16-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 SUPERFAMILY SSF53067 265 508 1.73E-80 T 16-09-2016 Spa2297_RS06450 0776151c2ed2efdc655d5b2c115e5002 512 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 9 507 6.3E-227 T 16-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 PANTHER PTHR30118:SF4 1 305 1.3E-119 T 16-09-2016 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-5 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-5 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-5 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 SUPERFAMILY SSF46785 3 83 1.87E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.7E-17 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Gene3D G3DSA:3.40.190.10 283 298 2.9E-25 T 16-09-2016 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Gene3D G3DSA:3.40.190.10 88 176 2.9E-25 T 16-09-2016 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 PANTHER PTHR30118 1 305 1.3E-119 T 16-09-2016 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Gene3D G3DSA:3.40.190.10 177 266 1.1E-16 T 16-09-2016 Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Pfam PF03466 LysR substrate binding domain 93 296 1.3E-27 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 Gene3D G3DSA:1.10.10.10 3 84 9.6E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01550 125d7456f17662168df911a9cb4b709f 311 SUPERFAMILY SSF53850 88 294 9.31E-38 T 16-09-2016 Spa2297_RS02670 3f9960d1dcfdeb195c5c9ccad306daf1 297 Pfam PF07859 alpha/beta hydrolase fold 81 198 3.7E-13 T 16-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 Spa2297_RS02670 3f9960d1dcfdeb195c5c9ccad306daf1 297 Gene3D G3DSA:3.40.50.1820 36 271 4.2E-41 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02670 3f9960d1dcfdeb195c5c9ccad306daf1 297 SUPERFAMILY SSF53474 20 271 1.2E-38 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02670 3f9960d1dcfdeb195c5c9ccad306daf1 297 PANTHER PTHR23024 1 222 1.7E-40 T 16-09-2016 Spa2297_RS02670 3f9960d1dcfdeb195c5c9ccad306daf1 297 PANTHER PTHR23024:SF163 1 222 1.7E-40 T 16-09-2016 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 SMART SM00530 29 84 1.1E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 Pfam PF13560 Helix-turn-helix domain 26 80 6.5E-13 T 16-09-2016 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 SUPERFAMILY SSF47413 24 78 4.22E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 PANTHER PTHR10245:SF18 1 286 4.9E-82 T 16-09-2016 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 Gene3D G3DSA:1.10.260.40 20 78 1.1E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS12580 40f442256dfdfc6dd932318de1db51c8 286 PANTHER PTHR10245 1 286 4.9E-82 T 16-09-2016 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 Gene3D G3DSA:3.50.50.60 5 73 4.3E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 Gene3D G3DSA:3.50.50.60 314 355 4.3E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 Gene3D G3DSA:3.50.50.60 120 198 4.3E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 PANTHER PTHR10617:SF109 1 472 1.3E-223 T 16-09-2016 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 Pfam PF04820 Tryptophan halogenase 9 73 2.4E-6 T 16-09-2016 IPR006905 Tryptophan halogenase Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 Pfam PF04820 Tryptophan halogenase 128 406 9.2E-10 T 16-09-2016 IPR006905 Tryptophan halogenase Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 SUPERFAMILY SSF51905 1 257 1.16E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 PANTHER PTHR10617 1 472 1.3E-223 T 16-09-2016 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 3.1E-7 T 16-09-2016 Spa2297_RS04645 8728e7264897f82d7f604bcde18bf0be 585 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 3.1E-7 T 16-09-2016 Spa2297_RS14190 09e997ae3bc053f3ad43df3769b48160 135 Gene3D G3DSA:3.30.70.1060 1 128 1.7E-38 T 16-09-2016 Spa2297_RS14190 09e997ae3bc053f3ad43df3769b48160 135 PANTHER PTHR35174:SF3 3 131 3.8E-31 T 16-09-2016 Spa2297_RS14190 09e997ae3bc053f3ad43df3769b48160 135 SUPERFAMILY SSF54909 21 125 9.65E-24 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS14190 09e997ae3bc053f3ad43df3769b48160 135 PANTHER PTHR35174 3 131 3.8E-31 T 16-09-2016 Spa2297_RS14190 09e997ae3bc053f3ad43df3769b48160 135 Pfam PF03795 YCII-related domain 17 109 6.5E-12 T 16-09-2016 IPR005545 YCII-related Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Gene3D G3DSA:3.30.9.10 179 273 3.8E-41 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Gene3D G3DSA:3.30.9.10 88 119 3.8E-41 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 PANTHER PTHR11530:SF10 6 314 2.1E-155 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 PIRSF PIRSF000189 6 317 2.2E-71 T 16-09-2016 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Pfam PF01266 FAD dependent oxidoreductase 9 312 1.4E-38 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 SUPERFAMILY SSF51971 8 198 1.02E-28 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 SUPERFAMILY SSF51971 260 314 1.02E-28 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 PANTHER PTHR11530 6 314 2.1E-155 T 16-09-2016 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 SUPERFAMILY SSF54373 185 274 1.14E-20 T 16-09-2016 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Gene3D G3DSA:3.50.50.60 8 77 1.8E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Gene3D G3DSA:3.50.50.60 285 314 1.8E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 Gene3D G3DSA:3.50.50.60 121 178 1.8E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28070 bca921bdb9359be4e75640566b04f888 317 ProSitePatterns PS00677 D-amino acid oxidases signature. 290 308 - T 16-09-2016 IPR006181 D-amino acid oxidase, conserved site GO:0003884|GO:0055114 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 Gene3D G3DSA:3.40.50.300 20 327 1.3E-104 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 PANTHER PTHR10285:SF7 11 274 7.1E-155 T 16-09-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 20 328 1.8E-124 T 16-09-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 SUPERFAMILY SSF52540 18 327 5.91E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 PANTHER PTHR10285 290 329 7.1E-155 T 16-09-2016 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 PANTHER PTHR10285 11 274 7.1E-155 T 16-09-2016 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 102 246 1.4E-11 T 16-09-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 Hamap MF_00215 Pantothenate kinase [coaA]. 1 329 173.216 T 16-09-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 PANTHER PTHR10285:SF7 290 329 7.1E-155 T 16-09-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS19975 1cbde2a08b03d3dffaa4524e208bb440 329 PIRSF PIRSF000545 11 329 7.8E-144 T 16-09-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 Spa2297_RS12355 8a20338f64c6ae83cdcef3073dbb66a3 454 SUPERFAMILY SSF52266 232 441 7.18E-46 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS12355 8a20338f64c6ae83cdcef3073dbb66a3 454 PANTHER PTHR30383 85 443 1.4E-123 T 16-09-2016 Spa2297_RS12355 8a20338f64c6ae83cdcef3073dbb66a3 454 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 241 436 2.2E-24 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS12355 8a20338f64c6ae83cdcef3073dbb66a3 454 PANTHER PTHR30383:SF3 85 443 1.4E-123 T 16-09-2016 Spa2297_RS12355 8a20338f64c6ae83cdcef3073dbb66a3 454 Gene3D G3DSA:3.40.50.1110 238 441 5.4E-32 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Gene3D G3DSA:2.40.30.10 303 395 6.3E-47 T 16-09-2016 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 2.2E-13 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 SUPERFAMILY SSF50447 207 304 6.87E-31 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Gene3D G3DSA:2.40.30.10 214 301 3.7E-37 T 16-09-2016 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 SUPERFAMILY SSF52540 6 221 4.0E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.317 T 16-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 SUPERFAMILY SSF50465 305 397 2.1E-36 T 16-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PANTHER PTHR23115:SF112 1 397 2.3E-249 T 16-09-2016 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 4.0E-222 T 16-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.3E-58 T 16-09-2016 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Gene3D G3DSA:3.40.50.300 5 213 2.2E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 6.8E-17 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 4.7E-34 T 16-09-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Spa2297_RS19680 40a9a999cd7af27d3c691ca4a88a30f2 397 PANTHER PTHR23115 1 397 2.3E-249 T 16-09-2016 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 SUPERFAMILY SSF54211 236 347 1.06E-19 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 SUPERFAMILY SSF50156 140 255 8.68E-14 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 255 344 2.9E-7 T 16-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 PANTHER PTHR10046:SF48 232 355 1.3E-53 T 16-09-2016 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 Gene3D G3DSA:2.30.42.10 130 213 1.8E-13 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 Gene3D G3DSA:3.30.230.10 252 347 1.2E-20 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 Pfam PF13180 PDZ domain 138 201 1.2E-10 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 SMART SM00228 131 197 0.0014 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS21975 91269405c7d2efde5c0bf73610750746 364 PANTHER PTHR10046 232 355 1.3E-53 T 16-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 PANTHER PTHR30157 7 263 1.7E-116 T 16-09-2016 Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 Gene3D G3DSA:2.40.30.10 7 130 1.7E-35 T 16-09-2016 Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 Pfam PF04954 Siderophore-interacting protein 138 253 4.9E-39 T 16-09-2016 IPR007037 Siderophore-interacting protein Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 131 1.2E-38 T 16-09-2016 IPR013113 FAD-binding 9, siderophore-interacting Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 Gene3D G3DSA:3.40.50.80 133 274 3.0E-51 T 16-09-2016 Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 PANTHER PTHR30157:SF1 7 263 1.7E-116 T 16-09-2016 Spa2297_RS06270 210fba01dd59dbc7dfd8b61137470e1b 280 SUPERFAMILY SSF63380 7 131 4.31E-12 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Gene3D G3DSA:3.40.50.1100 43 147 1.6E-39 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Pfam PF00571 CBS domain 340 395 6.0E-5 T 16-09-2016 IPR000644 CBS domain Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Pfam PF00571 CBS domain 410 458 0.0011 T 16-09-2016 IPR000644 CBS domain Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 SMART SM00116 413 458 19.0 T 16-09-2016 IPR000644 CBS domain Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 SMART SM00116 340 396 0.14 T 16-09-2016 IPR000644 CBS domain Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 PANTHER PTHR10314 7 353 6.0E-255 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 3.5E-71 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 458 1.7E-214 T 16-09-2016 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801|UniPathway: UPA00136 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 SUPERFAMILY SSF53686 3 317 1.31E-98 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 PANTHER PTHR10314:SF104 7 353 6.0E-255 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 SUPERFAMILY SSF54631 339 458 1.77E-15 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 16-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Gene3D G3DSA:3.10.580.10 340 459 3.9E-20 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Gene3D G3DSA:3.40.50.1100 153 313 1.2E-70 T 16-09-2016 Spa2297_RS13360 66233f1d51127515b194fbf496209db2 461 Gene3D G3DSA:3.40.50.1100 3 42 1.2E-70 T 16-09-2016 Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 PANTHER PTHR19836:SF21 1 101 1.1E-72 T 16-09-2016 Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 SUPERFAMILY SSF57716 2 101 2.23E-32 T 16-09-2016 Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.502 T 16-09-2016 IPR023036 Ribosomal protein S14, bacterial/plastid Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 7.4E-24 T 16-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 PANTHER PTHR19836 1 101 1.1E-72 T 16-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18060 06cc357300f044da7f8219d7873e3ff4 101 Gene3D G3DSA:4.10.830.10 41 101 1.1E-27 T 16-09-2016 Spa2297_RS09915 15642049759e43ed8c6181adc9912e42 73 SMART SM00834 1 42 8.3E-15 T 16-09-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spa2297_RS09915 15642049759e43ed8c6181adc9912e42 73 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 48 2.1E-16 T 16-09-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spa2297_RS09915 15642049759e43ed8c6181adc9912e42 73 Pfam PF09723 Zinc ribbon domain 1 40 7.2E-13 T 16-09-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spa2297_RS09915 15642049759e43ed8c6181adc9912e42 73 PANTHER PTHR34404:SF1 2 73 3.9E-28 T 16-09-2016 Spa2297_RS09915 15642049759e43ed8c6181adc9912e42 73 PANTHER PTHR34404 2 73 3.9E-28 T 16-09-2016 Spa2297_RS06580 58d2722e2180fe7e337a9765e6fc511b 297 PANTHER PTHR40761:SF1 1 297 8.7E-95 T 16-09-2016 Spa2297_RS06580 58d2722e2180fe7e337a9765e6fc511b 297 PANTHER PTHR40761 1 297 8.7E-95 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 Gene3D G3DSA:3.30.870.10 246 400 7.8E-34 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 Gene3D G3DSA:3.30.870.10 37 231 9.8E-42 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 SMART SM00155 141 168 16.0 T 16-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 SMART SM00155 318 345 0.013 T 16-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 PANTHER PTHR21248 22 405 3.4E-99 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 Pfam PF13091 PLD-like domain 247 372 6.3E-26 T 16-09-2016 IPR025202 Phospholipase D-like domain Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 Pfam PF13091 PLD-like domain 60 162 1.8E-12 T 16-09-2016 IPR025202 Phospholipase D-like domain Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 SUPERFAMILY SSF56024 220 389 4.71E-34 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 PANTHER PTHR21248:SF5 22 405 3.4E-99 T 16-09-2016 Spa2297_RS02590 0ba6342bd36bb61dc67589944b7a756e 405 SUPERFAMILY SSF56024 39 230 4.08E-43 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Pfam PF02910 Fumarate reductase flavoprotein C-term 447 566 2.3E-21 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Pfam PF00890 FAD binding domain 20 399 3.6E-96 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 8.1E-11 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 8.1E-11 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Gene3D G3DSA:3.50.50.60 14 247 7.3E-98 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Gene3D G3DSA:3.50.50.60 356 416 7.3E-98 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 19 530 2.3E-165 T 16-09-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 4.8E-6 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 4.8E-6 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PANTHER PTHR11632:SF27 20 550 2.7E-233 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 SUPERFAMILY SSF51905 5 271 5.77E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 SUPERFAMILY SSF51905 363 422 5.77E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 SUPERFAMILY SSF46977 442 568 2.35E-31 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PIRSF PIRSF000171 15 560 2.8E-40 T 16-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Gene3D G3DSA:1.20.58.100 441 548 3.4E-26 T 16-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 PANTHER PTHR11632 20 550 2.7E-233 T 16-09-2016 Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 SUPERFAMILY SSF56425 242 359 4.49E-37 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS18290 bc515e2b533b9e264fc1820ee8fd6e2c 577 Gene3D G3DSA:3.90.700.10 248 355 1.3E-35 T 16-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 PANTHER PTHR11751:SF384 25 105 4.2E-21 T 16-09-2016 Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 SUPERFAMILY SSF48008 86 219 9.15E-20 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 SMART SM00895 89 214 8.7E-13 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 SMART SM00345 21 79 8.1E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 Pfam PF07729 FCD domain 90 213 1.3E-15 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 PANTHER PTHR11751 25 105 4.2E-21 T 16-09-2016 Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 4.9E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 4.9E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 SUPERFAMILY SSF46785 14 83 6.49E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 Gene3D G3DSA:1.10.10.10 11 80 3.3E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 Gene3D G3DSA:1.20.120.530 84 221 7.6E-23 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS31540 9e5ec58d95e3f23376403e671cb42009 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 79 1.0E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 PANTHER PTHR10314:SF36 4 320 1.2E-138 T 16-09-2016 Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 309 2.8E-82 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 Gene3D G3DSA:3.40.50.1100 75 320 1.3E-74 T 16-09-2016 Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 16-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 SUPERFAMILY SSF53686 9 317 1.23E-98 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS29570 036091894baa2f04e7a3f6e0ac61bcd3 325 PANTHER PTHR10314 4 320 1.2E-138 T 16-09-2016 Spa2297_RS30465 732ddd0a34ed64ab3c40320faadfa591 219 SMART SM00554 121 218 2.8E-29 T 16-09-2016 IPR000782 FAS1 domain Spa2297_RS30465 732ddd0a34ed64ab3c40320faadfa591 219 SUPERFAMILY SSF82153 79 218 1.31E-36 T 16-09-2016 IPR000782 FAS1 domain Spa2297_RS30465 732ddd0a34ed64ab3c40320faadfa591 219 Pfam PF02469 Fasciclin domain 97 217 1.3E-31 T 16-09-2016 IPR000782 FAS1 domain Spa2297_RS30465 732ddd0a34ed64ab3c40320faadfa591 219 Gene3D G3DSA:2.30.180.10 87 218 6.1E-34 T 16-09-2016 IPR000782 FAS1 domain Spa2297_RS30465 732ddd0a34ed64ab3c40320faadfa591 219 PANTHER PTHR10900 62 219 7.8E-47 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 PIRSF PIRSF004846 6 278 1.3E-64 T 16-09-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 Gene3D G3DSA:3.40.190.10 162 231 2.6E-8 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 PANTHER PTHR30632:SF0 44 277 6.8E-53 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 PANTHER PTHR30632 44 277 6.8E-53 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 SUPERFAMILY SSF53850 57 278 3.16E-53 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 Pfam PF13531 Bacterial extracellular solute-binding protein 59 275 9.8E-44 T 16-09-2016 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 63 272 3.7E-41 T 16-09-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 Spa2297_RS17220 9b3307d9e096cda618c9c7984489b0b2 278 Gene3D G3DSA:3.40.190.10 57 161 1.9E-33 T 16-09-2016 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 SMART SM00344 3 109 3.4E-28 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 PANTHER PTHR30154:SF12 1 153 9.4E-59 T 16-09-2016 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 8.3E-13 T 16-09-2016 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 SUPERFAMILY SSF54909 64 148 3.49E-20 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 Gene3D G3DSA:1.10.10.10 2 51 5.8E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 4.5E-20 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 Gene3D G3DSA:3.30.70.920 56 147 3.3E-23 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 SUPERFAMILY SSF46785 3 63 1.53E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 PANTHER PTHR30154 1 153 9.4E-59 T 16-09-2016 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.8E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.8E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS03755 034cc0747ab5b29697a8c38acb7e95f9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.8E-10 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Gene3D G3DSA:3.90.740.10 247 419 2.0E-40 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 35 658 2.2E-148 T 16-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Gene3D G3DSA:1.10.730.10 670 837 4.0E-37 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Pfam PF08264 Anticodon-binding domain of tRNA 709 842 9.7E-24 T 16-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PANTHER PTHR11946:SF87 13 267 1.1E-294 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PANTHER PTHR11946:SF87 290 911 1.1E-294 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Gene3D G3DSA:3.40.50.620 420 655 1.3E-120 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 Gene3D G3DSA:3.40.50.620 29 215 1.3E-120 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 SUPERFAMILY SSF52374 416 658 8.16E-109 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 SUPERFAMILY SSF52374 29 219 8.16E-109 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PANTHER PTHR11946 13 267 1.1E-294 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 414 429 3.0E-22 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 62 73 3.0E-22 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 583 592 3.0E-22 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 246 269 3.0E-22 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 543 556 3.0E-22 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 PANTHER PTHR11946 290 911 1.1E-294 T 16-09-2016 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 28 858 1.4E-195 T 16-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 SUPERFAMILY SSF47323 679 888 1.12E-40 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS02860 3b392d62504a93249367f6fbcad79211 1060 SUPERFAMILY SSF50677 227 414 2.51E-32 T 16-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 PANTHER PTHR30346 1 312 4.9E-94 T 16-09-2016 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 Gene3D G3DSA:3.40.190.10 183 267 6.8E-18 T 16-09-2016 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 PANTHER PTHR30346:SF6 1 312 4.9E-94 T 16-09-2016 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.0E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.0E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.0E-8 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 Gene3D G3DSA:1.10.10.10 3 88 9.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 Pfam PF03466 LysR substrate binding domain 95 292 1.2E-20 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 SUPERFAMILY SSF53850 94 291 3.57E-22 T 16-09-2016 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.0E-17 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 Gene3D G3DSA:3.40.190.10 107 182 3.5E-7 T 16-09-2016 Spa2297_RS19720 373cd7982e64853e62724fcef3674635 322 SUPERFAMILY SSF46785 3 114 5.28E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 SUPERFAMILY SSF52096 27 272 2.65E-73 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 Pfam PF01039 Carboxyl transferase domain 51 527 1.6E-152 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 PANTHER PTHR22855 6 538 0.0 T 16-09-2016 Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 SUPERFAMILY SSF52096 240 520 1.32E-89 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 Gene3D G3DSA:3.90.226.10 283 533 4.5E-96 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 Gene3D G3DSA:3.90.226.10 30 270 6.9E-80 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS11755 a4fd2e0ffdf7e552c909a781af3171f2 538 PANTHER PTHR22855:SF35 6 538 0.0 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 Gene3D G3DSA:1.10.260.40 27 82 1.5E-22 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 SUPERFAMILY SSF47413 28 86 4.02E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 SMART SM00354 28 98 2.6E-24 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 PANTHER PTHR30146:SF41 28 357 1.2E-221 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 Gene3D G3DSA:3.40.50.2300 193 351 1.3E-50 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 Pfam PF13377 Periplasmic binding protein-like domain 195 351 6.3E-29 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 PANTHER PTHR30146 28 357 1.2E-221 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 ProSitePatterns PS00356 LacI-type HTH domain signature. 31 49 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 Pfam PF00356 Bacterial regulatory proteins, lacI family 30 75 2.0E-14 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 Gene3D G3DSA:3.40.50.2300 83 192 2.5E-30 T 16-09-2016 Spa2297_RS03580 f86ea1fdd8957587175849cf38a9d6e9 358 SUPERFAMILY SSF53822 88 352 4.32E-63 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 SMART SM00939 352 608 1.1E-44 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 PANTHER PTHR11731:SF148 49 249 1.7E-67 T 16-09-2016 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 SUPERFAMILY SSF53474 36 387 6.7E-69 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 364 605 2.8E-45 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Gene3D G3DSA:3.40.50.1820 45 232 2.3E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Gene3D G3DSA:3.40.50.1820 292 379 2.3E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 PANTHER PTHR11731:SF148 273 372 1.7E-67 T 16-09-2016 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 64 337 1.4E-58 T 16-09-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Gene3D G3DSA:2.60.120.260 380 484 9.1E-40 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 Gene3D G3DSA:2.60.120.260 531 611 9.1E-40 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 PANTHER PTHR11731 273 372 1.7E-67 T 16-09-2016 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 PANTHER PTHR11731 49 249 1.7E-67 T 16-09-2016 Spa2297_RS28055 760c3324d0d1f0cdb46451669219c45b 653 SUPERFAMILY SSF49785 407 614 2.76E-36 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS24080 06c94c81e8ea883dc8746ec7a6164a94 389 Gene3D G3DSA:3.40.50.2000 185 355 8.0E-36 T 16-09-2016 Spa2297_RS24080 06c94c81e8ea883dc8746ec7a6164a94 389 Pfam PF00534 Glycosyl transferases group 1 193 357 9.0E-37 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS24080 06c94c81e8ea883dc8746ec7a6164a94 389 PANTHER PTHR12526:SF353 7 375 4.3E-115 T 16-09-2016 Spa2297_RS24080 06c94c81e8ea883dc8746ec7a6164a94 389 PANTHER PTHR12526 7 375 4.3E-115 T 16-09-2016 Spa2297_RS24080 06c94c81e8ea883dc8746ec7a6164a94 389 SUPERFAMILY SSF53756 11 373 2.42E-70 T 16-09-2016 Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 Gene3D G3DSA:3.40.710.10 143 483 1.1E-93 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 Pfam PF00905 Penicillin binding protein transpeptidase domain 154 479 5.5E-68 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 SUPERFAMILY SSF56601 137 483 1.37E-87 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 PANTHER PTHR30627 1 483 1.4E-176 T 16-09-2016 Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 Gene3D G3DSA:3.90.1310.10 75 142 1.8E-6 T 16-09-2016 Spa2297_RS07490 94c9d539327013d0274fd20be82e408e 484 PANTHER PTHR30627:SF3 1 483 1.4E-176 T 16-09-2016 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 Pfam PF01547 Bacterial extracellular solute-binding protein 82 375 2.6E-23 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 PANTHER PTHR30061 1 460 4.1E-213 T 16-09-2016 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 PANTHER PTHR30061:SF2 1 460 4.1E-213 T 16-09-2016 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 Gene3D G3DSA:3.40.190.10 76 197 4.9E-20 T 16-09-2016 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 Gene3D G3DSA:3.40.190.10 198 391 2.3E-27 T 16-09-2016 Spa2297_RS12870 b1ce73db2e9ba00cb334b28618c9e6c9 466 SUPERFAMILY SSF53850 67 464 2.03E-55 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 PANTHER PTHR37690 1 282 2.0E-75 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 SUPERFAMILY SSF53850 8 264 9.95E-73 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 Gene3D G3DSA:3.40.190.10 82 183 1.2E-35 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 Gene3D G3DSA:3.40.190.10 3 81 2.2E-67 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 Gene3D G3DSA:3.40.190.10 184 281 2.2E-67 T 16-09-2016 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 Hamap MF_00995 Chorismate dehydratase [mqnA]. 9 271 31.536 T 16-09-2016 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 Spa2297_RS18915 cc068a1307f7a72635d6fcb364313c36 282 Pfam PF02621 Menaquinone biosynthesis 9 265 5.3E-70 T 16-09-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 Gene3D G3DSA:2.40.10.10 284 386 1.4E-12 T 16-09-2016 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 2.1E-7 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 2.1E-7 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 2.1E-7 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 Pfam PF02674 Colicin V production protein 4 148 1.7E-21 T 16-09-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 SUPERFAMILY SSF50494 195 383 2.77E-36 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 PANTHER PTHR22939 54 384 3.1E-117 T 16-09-2016 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 3.7E-22 T 16-09-2016 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 PANTHER PTHR22939:SF106 54 384 3.1E-117 T 16-09-2016 Spa2297_RS17880 80ea48457288cb95e4b0d47f605669db 399 Gene3D G3DSA:2.40.10.10 193 276 3.3E-14 T 16-09-2016 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 Pfam PF04055 Radical SAM superfamily 189 359 7.0E-20 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 179 477 5.6E-81 T 16-09-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 477 3.2E-119 T 16-09-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 PANTHER PTHR11918:SF57 1 489 3.4E-193 T 16-09-2016 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 187 207 - T 16-09-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 Gene3D G3DSA:3.80.30.20 184 412 1.6E-61 T 16-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 SUPERFAMILY SSF102114 172 405 4.97E-45 T 16-09-2016 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 PANTHER PTHR11918 1 489 3.4E-193 T 16-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 SMART SM00729 183 401 1.5E-40 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 480 60.47 T 16-09-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 Gene3D G3DSA:2.40.50.140 416 481 5.8E-15 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS24330 880615d20c3a279549b896a3880fe623 493 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 2.1E-31 T 16-09-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 Spa2297_RS31385 0a95891523312980abe442ad5a79921a 199 PANTHER PTHR19372 11 199 1.6E-61 T 16-09-2016 Spa2297_RS31385 0a95891523312980abe442ad5a79921a 199 Gene3D G3DSA:3.90.420.10 23 195 2.6E-47 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS31385 0a95891523312980abe442ad5a79921a 199 Pfam PF00174 Oxidoreductase molybdopterin binding domain 35 179 9.3E-32 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS31385 0a95891523312980abe442ad5a79921a 199 SUPERFAMILY SSF56524 5 198 8.5E-56 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 SUPERFAMILY SSF51430 1 313 7.99E-92 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 PANTHER PTHR11732 232 336 6.1E-162 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 Gene3D G3DSA:3.20.20.100 1 312 8.7E-88 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 PANTHER PTHR11732:SF273 232 336 6.1E-162 T 16-09-2016 Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 Pfam PF00248 Aldo/keto reductase family 16 312 3.6E-67 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 PANTHER PTHR11732 1 211 6.1E-162 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS20925 1e6f80b15902da6159bd2b2f81b4981c 339 PANTHER PTHR11732:SF273 1 211 6.1E-162 T 16-09-2016 Spa2297_RS20870 028f53892096771b614ec2625d943528 266 SUPERFAMILY SSF52096 8 265 2.93E-82 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS20870 028f53892096771b614ec2625d943528 266 PANTHER PTHR11941:SF93 1 263 1.8E-128 T 16-09-2016 Spa2297_RS20870 028f53892096771b614ec2625d943528 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 16-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 Spa2297_RS20870 028f53892096771b614ec2625d943528 266 Gene3D G3DSA:1.10.12.10 207 266 1.1E-17 T 16-09-2016 IPR014748 Crontonase, C-terminal Spa2297_RS20870 028f53892096771b614ec2625d943528 266 PANTHER PTHR11941 1 263 1.8E-128 T 16-09-2016 Spa2297_RS20870 028f53892096771b614ec2625d943528 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 264 1.5E-59 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS20870 028f53892096771b614ec2625d943528 266 Gene3D G3DSA:3.90.226.10 11 206 1.3E-67 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS30980 517010ac93ee6a4f8905647dd44af5ab 254 PANTHER PTHR38589 1 254 7.0E-55 T 16-09-2016 Spa2297_RS30980 517010ac93ee6a4f8905647dd44af5ab 254 PANTHER PTHR38589:SF1 1 254 7.0E-55 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 SUPERFAMILY SSF56553 48 169 4.97E-42 T 16-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.247 T 16-09-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 PANTHER PTHR32108 12 324 1.5E-134 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.4E-115 T 16-09-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 5.8E-24 T 16-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Gene3D G3DSA:3.30.1360.10 7 61 5.7E-11 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 PANTHER PTHR32108:SF0 12 324 1.5E-134 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 16-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Gene3D G3DSA:3.30.1360.10 171 216 2.7E-4 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 16-09-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 16-09-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Gene3D G3DSA:1.10.150.20 245 319 9.2E-32 T 16-09-2016 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 16-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 16-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 Gene3D G3DSA:2.170.120.12 62 168 4.2E-45 T 16-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS19930 c12d147cad01bd158ef684ab61896d24 340 SMART SM00662 18 225 1.3E-94 T 16-09-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 Spa2297_RS16625 b2c2081bff7caf840451c74cbee9ed74 299 PANTHER PTHR34203 55 269 9.0E-17 T 16-09-2016 Spa2297_RS16625 b2c2081bff7caf840451c74cbee9ed74 299 Pfam PF05050 Methyltransferase FkbM domain 85 251 6.9E-13 T 16-09-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS16625 b2c2081bff7caf840451c74cbee9ed74 299 Gene3D G3DSA:3.40.50.150 64 260 1.1E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS16625 b2c2081bff7caf840451c74cbee9ed74 299 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 83 220 1.7E-29 T 16-09-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS16625 b2c2081bff7caf840451c74cbee9ed74 299 SUPERFAMILY SSF53335 29 260 1.07E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS05000 99e088940fa72aec41aaedc22f0adfb1 179 Gene3D G3DSA:1.10.1780.10 25 172 6.3E-16 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS05000 99e088940fa72aec41aaedc22f0adfb1 179 SUPERFAMILY SSF81923 25 67 2.75E-5 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS05000 99e088940fa72aec41aaedc22f0adfb1 179 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 141 170 0.52 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS05000 99e088940fa72aec41aaedc22f0adfb1 179 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 38 69 0.0075 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS03020 1441512ad00fd49f1fcf9badbede3fe0 136 SUPERFAMILY SSF53062 7 133 2.49E-25 T 16-09-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 Spa2297_RS03020 1441512ad00fd49f1fcf9badbede3fe0 136 Gene3D G3DSA:3.40.50.510 4 135 8.2E-40 T 16-09-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 Spa2297_RS03020 1441512ad00fd49f1fcf9badbede3fe0 136 Pfam PF03610 PTS system fructose IIA component 8 123 7.8E-24 T 16-09-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 Spa2297_RS03020 1441512ad00fd49f1fcf9badbede3fe0 136 PANTHER PTHR38594 5 135 3.4E-44 T 16-09-2016 Spa2297_RS03020 1441512ad00fd49f1fcf9badbede3fe0 136 PANTHER PTHR38594:SF1 5 135 3.4E-44 T 16-09-2016 Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 Gene3D G3DSA:1.10.238.10 8 76 1.9E-10 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 Pfam PF13499 EF-hand domain pair 11 81 1.5E-7 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 ProSitePatterns PS00018 EF-hand calcium-binding domain. 19 31 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 ProSitePatterns PS00018 EF-hand calcium-binding domain. 69 81 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 SUPERFAMILY SSF47473 4 165 1.24E-20 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 Gene3D G3DSA:1.10.238.10 77 111 4.2E-8 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 Gene3D G3DSA:1.10.238.10 112 161 2.1E-4 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 SMART SM00054 10 38 1.2 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 SMART SM00054 60 88 12.0 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31905 bc29871eea5a74786b5fcf2e8d3183b6 179 SMART SM00054 98 126 34.0 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 273 2.4E-49 T 16-09-2016 IPR003786 Protein FdhD GO:0016783 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 SUPERFAMILY SSF53927 4 273 3.31E-79 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 Gene3D G3DSA:3.40.140.10 138 275 4.1E-55 T 16-09-2016 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 Hamap MF_00187 Protein FdhD [fdhD]. 3 274 37.503 T 16-09-2016 IPR003786 Protein FdhD GO:0016783 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 Gene3D G3DSA:3.10.20.10 28 120 6.8E-27 T 16-09-2016 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 PANTHER PTHR30592 2 282 8.3E-110 T 16-09-2016 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 Pfam PF02634 FdhD/NarQ family 26 273 3.4E-80 T 16-09-2016 IPR003786 Protein FdhD GO:0016783 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 PIRSF PIRSF015626 1 278 5.5E-92 T 16-09-2016 IPR003786 Protein FdhD GO:0016783 Spa2297_RS27300 b1289f42ca6ff47827214c7adf348a45 282 PANTHER PTHR30592:SF1 2 282 8.3E-110 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 PANTHER PTHR12526 95 448 1.5E-94 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 PANTHER PTHR12526 4 63 1.5E-94 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 SUPERFAMILY SSF53756 24 433 1.18E-79 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 Pfam PF00534 Glycosyl transferases group 1 255 411 1.1E-27 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 Pfam PF13439 Glycosyltransferase Family 4 36 241 2.3E-26 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 PANTHER PTHR12526:SF397 95 448 1.5E-94 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 PANTHER PTHR12526:SF397 4 63 1.5E-94 T 16-09-2016 Spa2297_RS09695 6f2116eedc16beec74c619fcd81c0b92 462 Gene3D G3DSA:3.40.50.2000 223 411 3.9E-24 T 16-09-2016 Spa2297_RS29665 8c90496d5c208f074e51b28815f056c2 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 311 8.9E-42 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS29665 8c90496d5c208f074e51b28815f056c2 343 PANTHER PTHR32196:SF24 16 336 2.2E-129 T 16-09-2016 Spa2297_RS29665 8c90496d5c208f074e51b28815f056c2 343 PANTHER PTHR32196 16 336 2.2E-129 T 16-09-2016 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 SUPERFAMILY SSF54565 2 86 9.03E-33 T 16-09-2016 IPR023803 Ribosomal protein S16 domain Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 Gene3D G3DSA:3.30.1320.10 2 83 9.5E-32 T 16-09-2016 IPR023803 Ribosomal protein S16 domain Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 16-09-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 2.6E-31 T 16-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 PANTHER PTHR12919:SF20 2 135 8.9E-47 T 16-09-2016 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.845 T 16-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 PANTHER PTHR12919 2 135 8.9E-47 T 16-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS23740 0907722a2b14f44e9242a75937c80a6c 139 Pfam PF00886 Ribosomal protein S16 9 67 1.1E-22 T 16-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS07830 9937a106a1b7c46c6eb86ae611b8de4c 95 ProSitePatterns PS00202 Rubredoxin signature. 35 45 - T 16-09-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 Spa2297_RS07830 9937a106a1b7c46c6eb86ae611b8de4c 95 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 1 95 20.926 T 16-09-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 Spa2297_RS07830 9937a106a1b7c46c6eb86ae611b8de4c 95 Pfam PF13397 RNA polymerase-binding protein 1 92 9.8E-37 T 16-09-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 Gene3D G3DSA:3.40.50.300 23 241 8.2E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 SUPERFAMILY SSF52540 25 241 2.13E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 SMART SM00382 52 238 8.5E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 Pfam PF00005 ABC transporter 43 189 4.9E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 PANTHER PTHR24220 25 242 5.4E-116 T 16-09-2016 Spa2297_RS19690 6ac4a6aba73c5db4a8190e9ec0847b0f 275 PANTHER PTHR24220:SF559 25 242 5.4E-116 T 16-09-2016 Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 116 3.3E-24 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 PANTHER PTHR33495 1 121 2.2E-41 T 16-09-2016 Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 SUPERFAMILY SSF52091 16 121 1.53E-26 T 16-09-2016 IPR002645 STAS domain Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 Gene3D G3DSA:3.30.750.24 16 122 2.2E-35 T 16-09-2016 IPR002645 STAS domain Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 PANTHER PTHR33495:SF2 1 121 2.2E-41 T 16-09-2016 Spa2297_RS13305 8402176ce9ed6c2b3a01e61f9014ad68 125 Pfam PF13466 STAS domain 30 105 1.1E-17 T 16-09-2016 IPR002645 STAS domain Spa2297_RS32485 e843e84e7c4341f4d0c15cd341f27a8f 133 Pfam PF03663 Glycosyl hydrolase family 76 2 132 2.4E-13 T 16-09-2016 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 Spa2297_RS32485 e843e84e7c4341f4d0c15cd341f27a8f 133 SUPERFAMILY SSF48208 21 131 5.1E-13 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS32485 e843e84e7c4341f4d0c15cd341f27a8f 133 Gene3D G3DSA:1.50.10.10 56 118 8.6E-6 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 PANTHER PTHR28629 1 330 1.2E-166 T 16-09-2016 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 325 2.7E-148 T 16-09-2016 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00563+2.7.-.-|UniPathway: UPA00616 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 Gene3D G3DSA:3.30.1180.20 185 329 6.9E-52 T 16-09-2016 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 Pfam PF02733 Dak1 domain 17 324 5.3E-125 T 16-09-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 SUPERFAMILY SSF82549 11 329 1.57E-116 T 16-09-2016 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 Gene3D G3DSA:3.40.50.10440 11 182 5.7E-71 T 16-09-2016 Spa2297_RS03010 f1e2c7a22eff3e618b4060c0cc5793c9 330 PANTHER PTHR28629:SF2 1 330 1.2E-166 T 16-09-2016 Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 PANTHER PTHR34848 212 399 3.7E-72 T 16-09-2016 Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 Gene3D G3DSA:3.40.50.300 224 397 2.4E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 SUPERFAMILY SSF56281 2 154 6.08E-7 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 224 396 1.2E-50 T 16-09-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 SUPERFAMILY SSF52540 224 397 1.14E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08975 50b8b1bbc9fc5bc9532830bb710b2004 399 Gene3D G3DSA:3.60.15.10 3 75 5.8E-10 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 4.5E-19 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 4.5E-19 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 4.5E-19 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 4.5E-19 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 4.5E-19 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 SUPERFAMILY SSF54719 98 203 3.01E-37 T 16-09-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 SUPERFAMILY SSF46609 3 89 5.24E-30 T 16-09-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 99 198 2.3E-31 T 16-09-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 Gene3D G3DSA:1.10.287.990 22 84 1.9E-21 T 16-09-2016 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PIRSF PIRSF000349 1 207 2.4E-70 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 1.4E-29 T 16-09-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PANTHER PTHR11404 1 211 2.4E-155 T 16-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 PANTHER PTHR11404:SF27 1 211 2.4E-155 T 16-09-2016 Spa2297_RS11145 628a32afb9eec67be58c07a2b3a8a238 213 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 16-09-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 Pfam PF07690 Major Facilitator Superfamily 20 419 1.9E-49 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 SUPERFAMILY SSF103473 8 199 7.59E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 SUPERFAMILY SSF103473 254 468 7.59E-67 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 4.9E-7 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 4.9E-7 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 4.9E-7 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 PANTHER PTHR23501 1 480 1.2E-220 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 PANTHER PTHR23501:SF31 1 480 1.2E-220 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 Gene3D G3DSA:1.20.1250.20 280 465 2.6E-16 T 16-09-2016 Spa2297_RS30295 c081bb519ab7930521734db424c06e7b 489 Gene3D G3DSA:1.20.1250.20 10 194 2.9E-34 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 1.0E-5 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 1.0E-5 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 112 1.0E-5 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 Gene3D G3DSA:1.20.1250.20 277 468 1.1E-19 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 Gene3D G3DSA:1.20.1250.20 28 207 5.9E-32 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 SUPERFAMILY SSF103473 13 214 2.35E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 SUPERFAMILY SSF103473 262 465 2.35E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 Pfam PF07690 Major Facilitator Superfamily 32 389 2.2E-49 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 PANTHER PTHR23501:SF76 4 483 4.3E-192 T 16-09-2016 Spa2297_RS10685 6283b70dbafe8e62d60b7342f9717125 483 PANTHER PTHR23501 4 483 4.3E-192 T 16-09-2016 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PANTHER PTHR11533:SF163 31 464 3.6E-111 T 16-09-2016 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 SUPERFAMILY SSF63737 34 228 8.5E-40 T 16-09-2016 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 211 226 1.2E-10 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 164 179 1.2E-10 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 310 325 1.2E-10 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 329 341 1.2E-10 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 PANTHER PTHR11533 31 464 3.6E-111 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 SUPERFAMILY SSF55486 237 464 3.08E-50 T 16-09-2016 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 Gene3D G3DSA:1.10.390.10 324 464 4.1E-25 T 16-09-2016 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 Pfam PF01433 Peptidase family M1 311 355 3.8E-16 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS14910 f964ac1bf35f25576ea71cd67452c4da 467 Pfam PF01433 Peptidase family M1 51 278 3.6E-21 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737:SF13 12 99 1.4E-129 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737 12 99 1.4E-129 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737 324 420 1.4E-129 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737 161 301 1.4E-129 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737:SF13 324 420 1.4E-129 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PANTHER PTHR12737:SF13 161 301 1.4E-129 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 Gene3D G3DSA:3.75.10.10 7 75 5.9E-121 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 Gene3D G3DSA:3.75.10.10 161 419 5.9E-121 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 Pfam PF02274 Amidinotransferase 26 415 1.1E-96 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PIRSF PIRSF006356 1 418 5.2E-128 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 Hamap MF_00242 Arginine deiminase [arcA]. 9 418 47.207 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 SUPERFAMILY SSF55909 12 418 3.75E-132 T 16-09-2016 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 10 30 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 189 204 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 354 371 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 374 388 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 161 179 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS30595 02f9a67e7e42bb8430b710cb7748c09e 420 PRINTS PR01466 Bacterial arginine deiminase signature 397 415 6.1E-46 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PANTHER PTHR22773 6 529 3.8E-178 T 16-09-2016 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 13 528 2.8E-169 T 16-09-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 160 179 1.6E-40 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 413 439 1.6E-40 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 262 286 1.6E-40 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 190 214 1.6E-40 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 356 375 1.6E-40 T 16-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 PANTHER PTHR22773:SF40 6 529 3.8E-178 T 16-09-2016 Spa2297_RS19485 deea1b0a752ccae761e311ae2dff4004 532 Pfam PF00361 Proton-conducting membrane transporter 154 441 1.9E-60 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS01170 9d13d5884389841f92be4a73cf2b2090 432 PANTHER PTHR30574:SF5 56 431 2.1E-104 T 16-09-2016 Spa2297_RS01170 9d13d5884389841f92be4a73cf2b2090 432 Pfam PF04143 Sulphur transport 83 412 1.6E-57 T 16-09-2016 IPR007272 Sulphur transport domain Spa2297_RS01170 9d13d5884389841f92be4a73cf2b2090 432 PANTHER PTHR30574 56 431 2.1E-104 T 16-09-2016 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Pfam PF02927 Cellulase N-terminal ig-like domain 182 264 6.8E-24 T 16-09-2016 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 SUPERFAMILY SSF48208 275 745 2.62E-125 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Pfam PF02018 Carbohydrate binding domain 33 154 3.7E-14 T 16-09-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Gene3D G3DSA:2.60.40.10 182 271 8.5E-30 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Pfam PF00759 Glycosyl hydrolase family 9 275 739 1.3E-98 T 16-09-2016 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 716 734 - T 16-09-2016 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Gene3D G3DSA:1.50.10.10 275 745 7.3E-149 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 Gene3D G3DSA:2.60.120.260 33 169 6.3E-32 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 PANTHER PTHR22298 460 663 2.6E-26 T 16-09-2016 Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 SUPERFAMILY SSF81296 176 270 6.72E-23 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS29890 b6926e6281870e4fdd77e576006f509b 747 SUPERFAMILY SSF49785 32 170 2.89E-32 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 4 63 2.6E-16 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 1.6E-12 T 16-09-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 SUPERFAMILY SSF55604 5 76 5.23E-21 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 Gene3D G3DSA:3.30.1360.60 3 77 2.9E-27 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 PANTHER PTHR30009:SF4 1 77 2.3E-24 T 16-09-2016 Spa2297_RS12425 3c96c97d609af5333925238187629be5 77 PANTHER PTHR30009 1 77 2.3E-24 T 16-09-2016 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 SUPERFAMILY SSF53474 16 273 1.51E-45 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 4.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 4.1E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 PANTHER PTHR10992:SF771 16 277 5.7E-45 T 16-09-2016 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 Pfam PF00561 alpha/beta hydrolase fold 30 259 1.6E-21 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 Gene3D G3DSA:3.40.50.1820 16 273 1.1E-45 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04625 0d09e8b0ca56343f494b7714d90a90fa 292 PANTHER PTHR10992 16 277 5.7E-45 T 16-09-2016 Spa2297_RS08595 c75d3bf84542d8593a8a8d6c0753e46b 267 PANTHER PTHR10108:SF705 19 207 2.7E-20 T 16-09-2016 Spa2297_RS08595 c75d3bf84542d8593a8a8d6c0753e46b 267 Gene3D G3DSA:3.40.50.150 35 214 6.5E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08595 c75d3bf84542d8593a8a8d6c0753e46b 267 SUPERFAMILY SSF53335 23 215 1.25E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08595 c75d3bf84542d8593a8a8d6c0753e46b 267 PANTHER PTHR10108 19 207 2.7E-20 T 16-09-2016 Spa2297_RS08595 c75d3bf84542d8593a8a8d6c0753e46b 267 Pfam PF08242 Methyltransferase domain 50 147 5.4E-14 T 16-09-2016 IPR013217 Methyltransferase type 12 Spa2297_RS18025 764b606906b40e7824d5a7c9a2fe30fe 210 Pfam PF07077 Protein of unknown function (DUF1345) 36 198 2.3E-47 T 16-09-2016 IPR009781 Protein of unknown function DUF1345 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 SUPERFAMILY SSF53850 49 434 3.5E-69 T 16-09-2016 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 PANTHER PTHR30061:SF7 1 438 4.3E-120 T 16-09-2016 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 Gene3D G3DSA:3.40.190.10 22 160 4.8E-13 T 16-09-2016 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 PANTHER PTHR30061 1 438 4.3E-120 T 16-09-2016 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 Gene3D G3DSA:3.40.190.10 168 364 9.2E-36 T 16-09-2016 Spa2297_RS30920 9046d0c18e91a3fabfd5c122e706cfd4 442 Pfam PF01547 Bacterial extracellular solute-binding protein 64 350 5.7E-37 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 PANTHER PTHR30328 1 129 3.6E-23 T 16-09-2016 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 9.8E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 PANTHER PTHR30328:SF17 1 129 3.6E-23 T 16-09-2016 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 SUPERFAMILY SSF48498 89 228 3.0E-21 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 SUPERFAMILY SSF46689 20 83 1.13E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 Gene3D G3DSA:1.10.357.10 87 227 2.5E-37 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 Gene3D G3DSA:1.10.10.60 11 80 7.1E-19 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24975 dae5c738339b5a1a8b97b71638206b46 229 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 227 1.0E-8 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 SUPERFAMILY SSF50370 380 506 2.16E-19 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 Pfam PF00652 Ricin-type beta-trefoil lectin domain 382 505 2.7E-17 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 PANTHER PTHR11675 383 460 6.1E-19 T 16-09-2016 Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 PANTHER PTHR11675:SF55 383 460 6.1E-19 T 16-09-2016 Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 SMART SM00458 381 508 8.5E-7 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS29895 c8769fb3a3c3e14c5d872e8e22899687 528 Gene3D G3DSA:2.80.10.50 380 508 2.2E-17 T 16-09-2016 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 2.9E-11 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 87 2.9E-11 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 394 407 2.9E-11 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 289 308 2.9E-11 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 89 101 2.9E-11 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 SUPERFAMILY SSF50621 268 419 1.67E-27 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 SUPERFAMILY SSF51419 41 302 1.15E-52 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PANTHER PTHR11482:SF45 16 449 5.5E-164 T 16-09-2016 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 Gene3D G3DSA:3.20.20.10 43 285 2.0E-60 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 61 299 7.9E-39 T 16-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 Gene3D G3DSA:2.40.37.10 286 440 1.0E-30 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 241 256 - T 16-09-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 347 411 9.3E-6 T 16-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS13335 e31331af7ead44cfabe3902dd10df04f 461 PANTHER PTHR11482 16 449 5.5E-164 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 Gene3D G3DSA:3.40.50.150 152 351 6.8E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 Pfam PF01420 Type I restriction modification DNA specificity domain 530 661 3.9E-6 T 16-09-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 Pfam PF02384 N-6 DNA Methylase 130 431 1.4E-53 T 16-09-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 150 166 2.2E-20 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 174 188 2.2E-20 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 275 299 2.2E-20 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 247 259 2.2E-20 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 250 256 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 SUPERFAMILY SSF116734 514 680 1.55E-26 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 SUPERFAMILY SSF53335 131 468 3.64E-64 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PANTHER PTHR30408:SF4 136 456 1.7E-31 T 16-09-2016 Spa2297_RS21035 bf4662caa8fe26d49b3f1be393bbea8a 682 PANTHER PTHR30408 136 456 1.7E-31 T 16-09-2016 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 PANTHER PTHR32322 1 302 3.2E-111 T 16-09-2016 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 SUPERFAMILY SSF103481 194 284 3.92E-11 T 16-09-2016 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 Pfam PF00892 EamA-like transporter family 6 129 1.4E-14 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 Pfam PF00892 EamA-like transporter family 143 280 7.2E-16 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 SUPERFAMILY SSF103481 39 132 1.23E-11 T 16-09-2016 Spa2297_RS11650 c66b76d150c856e7e2b363abc4fdf41c 313 PANTHER PTHR32322:SF9 1 302 3.2E-111 T 16-09-2016 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 PIRSF PIRSF000089 1 320 3.3E-98 T 16-09-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 Gene3D G3DSA:3.40.50.1220 190 316 1.4E-58 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 Pfam PF01012 Electron transfer flavoprotein domain 4 172 2.3E-27 T 16-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 5.5E-36 T 16-09-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 16-09-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 PANTHER PTHR10909:SF294 148 314 2.7E-54 T 16-09-2016 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 SUPERFAMILY SSF52402 3 183 2.79E-35 T 16-09-2016 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 Gene3D G3DSA:3.40.50.620 1 184 3.4E-36 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 SMART SM00893 4 183 4.3E-23 T 16-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 PANTHER PTHR10909 148 314 2.7E-54 T 16-09-2016 Spa2297_RS03595 f9046f7f39f2e51d8acfbae55df59d7c 320 SUPERFAMILY SSF52467 194 314 3.27E-47 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 SUPERFAMILY SSF103473 265 465 9.16E-53 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 SUPERFAMILY SSF103473 20 218 9.16E-53 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 PANTHER PTHR23501 24 468 2.5E-145 T 16-09-2016 Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 Pfam PF07690 Major Facilitator Superfamily 40 426 9.0E-40 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 Gene3D G3DSA:1.20.1250.20 33 210 3.5E-19 T 16-09-2016 Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 Gene3D G3DSA:1.20.1250.20 280 467 1.1E-18 T 16-09-2016 Spa2297_RS12240 d42e99d1f2232bac695804668ad50515 469 PANTHER PTHR23501:SF7 24 468 2.5E-145 T 16-09-2016 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 96 7.3E-21 T 16-09-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 Gene3D G3DSA:1.20.1300.10 1 101 3.2E-27 T 16-09-2016 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 1 99 1.7E-26 T 16-09-2016 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 UniPathway: UPA00223 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 PANTHER PTHR41910 1 112 6.4E-38 T 16-09-2016 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 PIRSF PIRSF000178 1 104 1.9E-9 T 16-09-2016 Spa2297_RS20530 c42605b99b3717843057ae2df3d5a3cf 114 SUPERFAMILY SSF81343 1 101 2.94E-24 T 16-09-2016 Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 229 264 1.4E-12 T 16-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 SUPERFAMILY SSF57716 231 265 4.75E-9 T 16-09-2016 Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 PRINTS PR00618 DksA/TraR zinc finger signature 246 258 4.9E-5 T 16-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 PRINTS PR00618 DksA/TraR zinc finger signature 234 245 4.9E-5 T 16-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 234 258 - T 16-09-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 SUPERFAMILY SSF109635 134 230 4.84E-12 T 16-09-2016 Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 PANTHER PTHR33823 123 266 6.9E-113 T 16-09-2016 Spa2297_RS08480 caadf05667188efb41f828d8b4e7e38e 266 PANTHER PTHR33823:SF7 123 266 6.9E-113 T 16-09-2016 Spa2297_RS27145 3063105fb91d2e16ba5c517ba2f69b18 132 Pfam PF11387 Protein of unknown function (DUF2795) 74 116 6.5E-9 T 16-09-2016 IPR021527 Protein of unknown function DUF2795 Spa2297_RS18760 a5da453f3a083b8c94c09ed6ac5efdc9 183 Pfam PF01966 HD domain 3 106 5.5E-10 T 16-09-2016 IPR006674 HD domain Spa2297_RS18760 a5da453f3a083b8c94c09ed6ac5efdc9 183 PANTHER PTHR35569:SF1 1 183 4.1E-65 T 16-09-2016 Spa2297_RS18760 a5da453f3a083b8c94c09ed6ac5efdc9 183 SUPERFAMILY SSF109604 3 97 2.12E-15 T 16-09-2016 Spa2297_RS18760 a5da453f3a083b8c94c09ed6ac5efdc9 183 PANTHER PTHR35569 1 183 4.1E-65 T 16-09-2016 Spa2297_RS18760 a5da453f3a083b8c94c09ed6ac5efdc9 183 Gene3D G3DSA:1.10.3210.10 3 87 2.9E-8 T 16-09-2016 IPR006674 HD domain Spa2297_RS01245 4e4d237011a1cc60f88485ccaf124e92 495 PANTHER PTHR30618 5 481 0.0 T 16-09-2016 Spa2297_RS01245 4e4d237011a1cc60f88485ccaf124e92 495 PANTHER PTHR30618:SF6 5 481 0.0 T 16-09-2016 Spa2297_RS01245 4e4d237011a1cc60f88485ccaf124e92 495 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 31 464 4.4E-80 T 16-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 SUPERFAMILY SSF48576 19 303 1.44E-70 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 Pfam PF00494 Squalene/phytoene synthase 29 291 3.2E-63 T 16-09-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 174 199 - T 16-09-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 PANTHER PTHR31480 1 317 5.9E-85 T 16-09-2016 Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 142 157 - T 16-09-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Spa2297_RS00760 88fbd54bdbca83e031e70b15f1dfb6a7 331 Gene3D G3DSA:1.10.600.10 16 306 4.9E-72 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 PANTHER PTHR11815 1 377 3.2E-161 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 PIRSF PIRSF001554 1 376 1.5E-125 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Gene3D G3DSA:3.30.1490.20 23 87 3.7E-16 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 374 38.716 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Gene3D G3DSA:3.30.470.20 88 217 8.3E-44 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Gene3D G3DSA:3.40.50.261 227 370 3.5E-50 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 244 268 - T 16-09-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Pfam PF00549 CoA-ligase 251 343 2.7E-12 T 16-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 Pfam PF08442 ATP-grasp domain 2 190 2.6E-65 T 16-09-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 SUPERFAMILY SSF52210 226 370 2.88E-41 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 SUPERFAMILY SSF56059 1 217 2.55E-60 T 16-09-2016 Spa2297_RS27435 3d16823f58cb86c8a556778530cbaadb 380 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 370 1.1E-116 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 2.9E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 SMART SM00345 13 71 6.8E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 SMART SM00895 81 202 1.3E-8 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 SUPERFAMILY SSF48008 78 191 2.04E-17 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 Gene3D G3DSA:1.20.120.530 74 190 2.8E-18 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 SUPERFAMILY SSF46785 8 100 1.28E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 Pfam PF07729 FCD domain 82 191 2.8E-16 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 Gene3D G3DSA:1.10.10.10 7 72 7.8E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09020 251c465a0e0621ce0489329716ade3ac 207 PANTHER PTHR11751 8 97 1.5E-25 T 16-09-2016 Spa2297_RS19160 f21e45ea9a1766f56a9f4a7b8e1282c8 200 Gene3D G3DSA:2.30.40.10 12 118 1.8E-5 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS19160 f21e45ea9a1766f56a9f4a7b8e1282c8 200 Gene3D G3DSA:2.30.40.10 189 199 1.8E-5 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS19160 f21e45ea9a1766f56a9f4a7b8e1282c8 200 SUPERFAMILY SSF51338 9 54 1.3E-10 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14955 d600e679d3bc691b662c79785288376b 225 Pfam PF14065 Protein of unknown function (DUF4255) 4 181 3.0E-47 T 16-09-2016 IPR025351 Protein of unknown function DUF4255 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SMART SM00304 141 194 6.5E-13 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 413 2.0E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SUPERFAMILY SSF158472 142 191 1.02E-8 T 16-09-2016 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 PANTHER PTHR24423 21 26 1.5E-64 T 16-09-2016 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 PANTHER PTHR24423 135 414 1.5E-64 T 16-09-2016 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SUPERFAMILY SSF55874 252 414 3.67E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 196 260 3.0E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SMART SM00388 195 261 5.0E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 9.8E-9 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 369 9.8E-9 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 9.8E-9 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 Gene3D G3DSA:1.10.287.130 185 257 7.5E-10 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 Pfam PF00672 HAMP domain 122 191 2.1E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 Gene3D G3DSA:3.30.565.10 263 414 3.5E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SMART SM00387 303 414 2.7E-24 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24835 9c2aa4ef63089def2f07a32c21755b61 414 SUPERFAMILY SSF47384 178 260 2.16E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 PANTHER PTHR11751:SF361 10 386 2.5E-245 T 16-09-2016 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 Gene3D G3DSA:3.40.640.10 49 253 9.5E-47 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 Gene3D G3DSA:3.90.1150.10 254 384 6.9E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 PANTHER PTHR11751 10 386 2.5E-245 T 16-09-2016 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 Pfam PF00155 Aminotransferase class I and II 35 378 3.3E-41 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS31315 3faaa5f2f8ed218932ba3dfb4c041ee6 390 SUPERFAMILY SSF53383 7 383 3.99E-83 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 Pfam PF01740 STAS domain 8 110 1.1E-18 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 PANTHER PTHR33495 1 112 6.4E-38 T 16-09-2016 Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 107 5.9E-28 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 SUPERFAMILY SSF52091 6 111 7.85E-27 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 Gene3D G3DSA:3.30.750.24 6 112 9.4E-34 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00965 11bc777f5c671240ede8595ca220082b 114 PANTHER PTHR33495:SF2 1 112 6.4E-38 T 16-09-2016 Spa2297_RS29135 5723960559a3cefef0cac0aaa6666f02 157 PIRSF PIRSF016702 1 145 3.7E-37 T 16-09-2016 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif Spa2297_RS29135 5723960559a3cefef0cac0aaa6666f02 157 PANTHER PTHR34988 1 148 2.3E-42 T 16-09-2016 Spa2297_RS29135 5723960559a3cefef0cac0aaa6666f02 157 SUPERFAMILY SSF117856 12 140 2.3E-30 T 16-09-2016 Spa2297_RS29135 5723960559a3cefef0cac0aaa6666f02 157 Pfam PF03479 Domain of unknown function (DUF296) 13 122 6.9E-19 T 16-09-2016 IPR005175 PPC domain Spa2297_RS29135 5723960559a3cefef0cac0aaa6666f02 157 Gene3D G3DSA:3.30.1330.80 12 143 7.1E-35 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 Gene3D G3DSA:3.90.1550.10 179 250 1.3E-76 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 Gene3D G3DSA:3.90.1550.10 14 136 1.3E-76 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 SUPERFAMILY SSF55681 14 132 2.24E-61 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 SUPERFAMILY SSF55681 178 251 2.24E-61 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 129 9.0E-24 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 Hamap MF_00013 Octanoyltransferase [lipB]. 3 253 32.917 T 16-09-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 PIRSF PIRSF016262 3 263 5.2E-59 T 16-09-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 16-09-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 PANTHER PTHR10993 177 255 5.2E-73 T 16-09-2016 Spa2297_RS09070 1566e0a02f634a50765ada655cc2bee0 266 PANTHER PTHR10993 1 134 5.2E-73 T 16-09-2016 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 PANTHER PTHR30177:SF10 56 326 9.4E-164 T 16-09-2016 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 SUPERFAMILY SSF161098 454 637 5.36E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 476 638 4.5E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 321 3.9E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 PANTHER PTHR30177 56 326 9.4E-164 T 16-09-2016 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 Gene3D G3DSA:1.10.3720.10 138 318 1.3E-31 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 Gene3D G3DSA:1.10.3720.10 452 633 6.3E-31 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20380 7dbbf308df924526abb6f038ad24f362 648 SUPERFAMILY SSF161098 139 321 1.01E-32 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22945 2d43a57f39672eb05a2697bbd3addbe4 237 Gene3D G3DSA:1.10.260.40 89 147 1.4E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS22945 2d43a57f39672eb05a2697bbd3addbe4 237 Gene3D G3DSA:1.10.260.40 24 86 7.2E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS22945 2d43a57f39672eb05a2697bbd3addbe4 237 SMART SM00530 22 84 0.013 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS22945 2d43a57f39672eb05a2697bbd3addbe4 237 SMART SM00530 90 146 0.0063 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS22945 2d43a57f39672eb05a2697bbd3addbe4 237 SUPERFAMILY SSF47413 89 151 6.65E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25745 99e387c76da967b2d513416a20cef921 298 PANTHER PTHR30151 10 294 6.1E-136 T 16-09-2016 Spa2297_RS25745 99e387c76da967b2d513416a20cef921 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 280 8.5E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25745 99e387c76da967b2d513416a20cef921 298 PANTHER PTHR30151:SF16 10 294 6.1E-136 T 16-09-2016 Spa2297_RS25745 99e387c76da967b2d513416a20cef921 298 Gene3D G3DSA:1.10.3720.10 90 280 5.1E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25745 99e387c76da967b2d513416a20cef921 298 SUPERFAMILY SSF161098 90 278 1.44E-28 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 SMART SM01232 126 218 1.5E-37 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 PANTHER PTHR22993 2 272 2.6E-55 T 16-09-2016 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 Gene3D G3DSA:3.20.190.10 2 126 1.0E-13 T 16-09-2016 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 Pfam PF06827 Zinc finger found in FPG and IleRS 247 273 1.4E-4 T 16-09-2016 IPR010663 Zinc finger, FPG/IleRS-type Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 ProSitePatterns PS01242 Zinc finger FPG-type signature. 247 271 - T 16-09-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 SUPERFAMILY SSF81624 2 127 9.16E-22 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 SUPERFAMILY SSF57716 224 272 9.03E-12 T 16-09-2016 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 Gene3D G3DSA:1.10.8.50 127 272 3.5E-44 T 16-09-2016 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 17 107 1.2E-6 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 SMART SM00898 2 112 7.8E-18 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 126 209 3.2E-22 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS11120 07ef3ffdf341cb8bbabcfe54871abd40 273 SUPERFAMILY SSF46946 125 209 4.19E-26 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322:SF506 341 387 3.9E-45 T 16-09-2016 Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 Gene3D G3DSA:3.40.50.720 333 475 2.5E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 Gene3D G3DSA:3.40.50.720 138 242 2.5E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322 407 440 3.9E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322 160 250 3.9E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322:SF506 407 440 3.9E-45 T 16-09-2016 Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322:SF506 160 250 3.9E-45 T 16-09-2016 Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 PANTHER PTHR24322 341 387 3.9E-45 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 Pfam PF00106 short chain dehydrogenase 156 245 5.4E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 SUPERFAMILY SSF51735 152 250 3.11E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28870 8493e6310ed3b187a06b2e293e37ffe6 497 SUPERFAMILY SSF51735 338 442 3.11E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF49899 662 806 3.01E-20 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF16353 Domain of unknown function(DUF4981) 893 983 7.8E-24 T 16-09-2016 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PANTHER PTHR10066 80 623 0.0 T 16-09-2016 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:2.60.40.320 890 987 6.2E-26 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 506 520 - T 16-09-2016 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:3.20.20.80 829 877 6.9E-102 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:3.20.20.80 395 622 6.9E-102 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:2.60.40.320 264 393 5.9E-33 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 666 805 8.3E-19 T 16-09-2016 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF49303 874 985 5.32E-23 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:2.60.120.200 665 807 2.2E-17 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PANTHER PTHR10066:SF72 80 623 0.0 T 16-09-2016 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF00703 Glycosyl hydrolases family 2 276 393 1.1E-13 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF74650 1001 1287 5.96E-83 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:2.60.120.260 56 263 2.0E-77 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 99 274 1.7E-40 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SMART SM01038 1012 1285 8.6E-123 T 16-09-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PANTHER PTHR10066 847 1289 0.0 T 16-09-2016 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 830 881 2.3E-8 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 395 625 2.6E-80 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF51445 397 629 1.36E-71 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 445 470 - T 16-09-2016 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF49303 276 393 5.76E-22 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PRINTS PR00132 Glycosyl hydrolase family 2 signature 404 418 8.9E-30 T 16-09-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PRINTS PR00132 Glycosyl hydrolase family 2 signature 578 593 8.9E-30 T 16-09-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PRINTS PR00132 Glycosyl hydrolase family 2 signature 435 453 8.9E-30 T 16-09-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PRINTS PR00132 Glycosyl hydrolase family 2 signature 506 521 8.9E-30 T 16-09-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PRINTS PR00132 Glycosyl hydrolase family 2 signature 202 217 8.9E-30 T 16-09-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 PANTHER PTHR10066:SF72 847 1289 0.0 T 16-09-2016 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SMART SM00560 673 803 2.4E-49 T 16-09-2016 IPR006558 LamG-like jellyroll fold Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Pfam PF02929 Beta galactosidase small chain 1015 1284 1.5E-75 T 16-09-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 SUPERFAMILY SSF49785 58 274 6.56E-64 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26875 fe9f6e6bfc53fedb25a06eb42992a169 1304 Gene3D G3DSA:2.70.98.10 999 1287 6.6E-95 T 16-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 Spa2297_RS03260 8093c98d51581bc73350ba615b1813b6 159 PANTHER PTHR31793:SF2 7 155 3.9E-62 T 16-09-2016 Spa2297_RS03260 8093c98d51581bc73350ba615b1813b6 159 Gene3D G3DSA:3.10.129.10 5 145 9.1E-49 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS03260 8093c98d51581bc73350ba615b1813b6 159 Pfam PF13279 Thioesterase-like superfamily 11 138 1.5E-18 T 16-09-2016 Spa2297_RS03260 8093c98d51581bc73350ba615b1813b6 159 SUPERFAMILY SSF54637 7 155 1.28E-34 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS03260 8093c98d51581bc73350ba615b1813b6 159 PANTHER PTHR31793 7 155 3.9E-62 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 Pfam PF08386 TAP-like protein 411 515 3.4E-31 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992:SF878 389 505 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992:SF878 27 154 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992 27 154 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992 389 505 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992 197 288 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 PANTHER PTHR10992:SF878 197 288 4.0E-105 T 16-09-2016 Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 SUPERFAMILY SSF53474 196 488 4.8E-27 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 SUPERFAMILY SSF53474 89 153 4.8E-27 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 Gene3D G3DSA:3.40.50.1820 70 155 1.9E-54 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 Gene3D G3DSA:3.40.50.1820 199 323 1.9E-54 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21870 d555ff4ca21e2596f7bfd3e7a72af0f0 516 Gene3D G3DSA:3.40.50.1820 382 503 1.9E-54 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 PIRSF PIRSF006485 52 490 2.3E-157 T 16-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 SUPERFAMILY SSF52540 55 218 7.49E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 56 175 7.9E-25 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 229 395 5.7E-21 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 54 482 3.1E-156 T 16-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Gene3D G3DSA:3.40.50.300 54 218 2.6E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Gene3D G3DSA:3.40.50.300 229 409 5.2E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 404 482 1.2E-24 T 16-09-2016 IPR032859 GTPase Der, C-terminal KH-domain-like Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 PANTHER PTHR11649 16 487 8.1E-133 T 16-09-2016 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 SUPERFAMILY SSF52540 188 486 7.41E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Hamap MF_00195 GTPase Der [der]. 53 485 35.493 T 16-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Pfam PF01926 50S ribosome-binding GTPase 56 170 5.0E-25 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Pfam PF01926 50S ribosome-binding GTPase 230 348 7.9E-21 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 Gene3D G3DSA:3.30.300.20 410 484 3.4E-27 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 SMART SM00382 52 216 0.54 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 SMART SM00382 227 370 9.9E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 231 251 7.8E-6 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 280 295 7.8E-6 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS06925 7336eeaf8b56d98b434a58546f3fd13a 492 PANTHER PTHR11649:SF5 16 487 8.1E-133 T 16-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 Spa2297_RS06590 51dfbca53ca6844f6c582b3999e1b22c 130 Pfam PF02656 Domain of unknown function (DUF202) 27 92 7.8E-15 T 16-09-2016 IPR003807 Domain of unknown function DUF202 Spa2297_RS06590 51dfbca53ca6844f6c582b3999e1b22c 130 PANTHER PTHR34187 9 130 1.4E-31 T 16-09-2016 Spa2297_RS18245 7760b6d8a3b5d7dafb8d647a5dfc8dc5 362 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 120 273 5.1E-10 T 16-09-2016 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Spa2297_RS18245 7760b6d8a3b5d7dafb8d647a5dfc8dc5 362 SUPERFAMILY SSF53335 14 343 3.16E-40 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08465 143ce380038b3db80f59594e0aee58b7 161 PANTHER PTHR13355 18 161 1.8E-34 T 16-09-2016 Spa2297_RS08465 143ce380038b3db80f59594e0aee58b7 161 Pfam PF13673 Acetyltransferase (GNAT) domain 30 160 1.3E-17 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS08465 143ce380038b3db80f59594e0aee58b7 161 PANTHER PTHR13355:SF8 18 161 1.8E-34 T 16-09-2016 Spa2297_RS08465 143ce380038b3db80f59594e0aee58b7 161 Gene3D G3DSA:3.40.630.30 12 161 2.9E-38 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS08465 143ce380038b3db80f59594e0aee58b7 161 SUPERFAMILY SSF55729 10 161 2.23E-40 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 Gene3D G3DSA:3.90.1150.10 266 352 7.3E-27 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 PANTHER PTHR10289:SF8 1 356 1.5E-176 T 16-09-2016 Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 Pfam PF01212 Beta-eliminating lyase 19 304 7.9E-56 T 16-09-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 SUPERFAMILY SSF53383 17 353 4.73E-93 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 PANTHER PTHR10289 1 356 1.5E-176 T 16-09-2016 Spa2297_RS03625 369c33dab9c5386e02326c7e4b35c213 356 Gene3D G3DSA:3.40.640.10 11 263 6.9E-62 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 Gene3D G3DSA:3.40.50.980 182 307 1.7E-16 T 16-09-2016 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 Pfam PF00501 AMP-binding enzyme 48 433 4.0E-54 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 Gene3D G3DSA:3.30.300.30 447 536 4.1E-8 T 16-09-2016 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 PANTHER PTHR24095 52 534 7.3E-50 T 16-09-2016 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 Gene3D G3DSA:2.30.38.10 354 427 1.8E-18 T 16-09-2016 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 SUPERFAMILY SSF56801 43 535 2.88E-84 T 16-09-2016 Spa2297_RS26625 78cbc57cbf6f786b5eb41d2d556a9970 549 Gene3D G3DSA:3.40.50.980 49 181 1.7E-22 T 16-09-2016 Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 Pfam PF00905 Penicillin binding protein transpeptidase domain 456 623 4.9E-24 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 SUPERFAMILY SSF53955 56 275 7.59E-58 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 SUPERFAMILY SSF56601 286 413 6.84E-75 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 SUPERFAMILY SSF56601 440 701 6.84E-75 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 SUPERFAMILY SSF56601 234 256 6.84E-75 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 PANTHER PTHR32282:SF8 1 766 0.0 T 16-09-2016 Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 PANTHER PTHR32282 1 766 0.0 T 16-09-2016 Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 Gene3D G3DSA:3.40.710.10 257 717 3.8E-94 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 Pfam PF00912 Transglycosylase 72 246 1.3E-53 T 16-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 Spa2297_RS16465 084b072a0672822e56a7612ae06804fc 785 Gene3D G3DSA:1.10.3810.10 68 256 1.2E-57 T 16-09-2016 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PANTHER PTHR11999:SF70 9 492 4.9E-132 T 16-09-2016 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 42 411 3.6E-84 T 16-09-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 SUPERFAMILY SSF53383 9 486 4.68E-127 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PANTHER PTHR11999 9 492 4.9E-132 T 16-09-2016 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 Gene3D G3DSA:3.40.640.10 91 364 1.1E-93 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 Gene3D G3DSA:3.90.1150.10 365 487 1.6E-30 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 Gene3D G3DSA:1.20.1340.10 8 88 6.3E-20 T 16-09-2016 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 120 139 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 350 365 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 101 119 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 13 32 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS02925 5bc4445b57dd492d075148fc06bdffc0 503 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 54 73 9.2E-27 T 16-09-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 Spa2297_RS11135 398b3a5013445730b723970f15280ab1 196 PANTHER PTHR34295 1 192 1.7E-69 T 16-09-2016 Spa2297_RS11135 398b3a5013445730b723970f15280ab1 196 PANTHER PTHR34295:SF1 1 192 1.7E-69 T 16-09-2016 Spa2297_RS11135 398b3a5013445730b723970f15280ab1 196 Pfam PF02632 BioY family 52 191 3.1E-33 T 16-09-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Spa2297_RS11135 398b3a5013445730b723970f15280ab1 196 PIRSF PIRSF016661 15 196 4.4E-39 T 16-09-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Spa2297_RS22860 83230043482a0df1b617791a43baadb6 258 PANTHER PTHR38074 4 246 3.5E-86 T 16-09-2016 Spa2297_RS22860 83230043482a0df1b617791a43baadb6 258 PANTHER PTHR38074:SF1 4 246 3.5E-86 T 16-09-2016 Spa2297_RS22860 83230043482a0df1b617791a43baadb6 258 Gene3D G3DSA:3.60.160.10 18 211 1.5E-22 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS22860 83230043482a0df1b617791a43baadb6 258 SUPERFAMILY SSF51219 18 211 1.23E-29 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS22860 83230043482a0df1b617791a43baadb6 258 Pfam PF01987 Mitochondrial biogenesis AIM24 24 209 6.5E-10 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS11480 d7178b9e6f258f30423812b243a30386 381 SUPERFAMILY SSF55729 183 337 6.36E-8 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11480 d7178b9e6f258f30423812b243a30386 381 Pfam PF13480 Acetyltransferase (GNAT) domain 181 327 1.6E-20 T 16-09-2016 Spa2297_RS11480 d7178b9e6f258f30423812b243a30386 381 SUPERFAMILY SSF55729 16 84 2.05E-5 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 PANTHER PTHR24220:SF416 9 389 2.2E-147 T 16-09-2016 Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 Gene3D G3DSA:3.40.50.300 6 233 4.6E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 Gene3D G3DSA:3.40.50.300 276 499 8.6E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 SUPERFAMILY SSF52540 7 231 3.75E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 Pfam PF00005 ABC transporter 280 434 3.3E-22 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 Pfam PF00005 ABC transporter 23 173 4.5E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 PANTHER PTHR24220 9 389 2.2E-147 T 16-09-2016 Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 SMART SM00382 32 229 6.9E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 SMART SM00382 289 483 4.3E-8 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 SUPERFAMILY SSF52540 276 496 8.64E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00275 86e1201305e0dba0fefb98fa9efc50c9 519 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 PANTHER PTHR10286 3 159 6.3E-68 T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 SUPERFAMILY SSF50324 3 158 6.15E-57 T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 Pfam PF00719 Inorganic pyrophosphatase 5 158 4.5E-51 T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.773 T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS18155 57a8ed528b787b5096b588711dec56d9 163 Gene3D G3DSA:3.90.80.10 2 159 1.8E-53 T 16-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PANTHER PTHR11686:SF12 1 357 0.0 T 16-09-2016 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PANTHER PTHR11686:SF12 393 611 0.0 T 16-09-2016 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PANTHER PTHR11686 1 357 0.0 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PANTHER PTHR11686 393 611 0.0 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 469 484 3.7E-16 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 3.7E-16 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 3.7E-16 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 244 260 3.7E-16 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 Pfam PF01019 Gamma-glutamyltranspeptidase 28 603 6.7E-111 T 16-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 SUPERFAMILY SSF56235 2 358 1.49E-126 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS26825 12295314c420da63ef8a510d9e7af7ab 611 SUPERFAMILY SSF56235 410 610 1.49E-126 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 Pfam PF00171 Aldehyde dehydrogenase family 17 474 2.1E-170 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 Gene3D G3DSA:3.40.309.10 261 440 7.8E-70 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 PANTHER PTHR11699:SF164 3 478 2.8E-252 T 16-09-2016 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 SUPERFAMILY SSF53720 3 478 8.77E-169 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 PANTHER PTHR11699 3 478 2.8E-252 T 16-09-2016 Spa2297_RS13285 50d0385f0553ed864be430b4583a424a 488 Gene3D G3DSA:3.40.605.10 3 260 3.5E-94 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS22425 0a48199159ff5f5e328913767c3057aa 294 PANTHER PTHR10459 126 278 2.4E-12 T 16-09-2016 Spa2297_RS22425 0a48199159ff5f5e328913767c3057aa 294 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 12 254 5.6E-85 T 16-09-2016 IPR014145 DNA ligase D, polymerase domain Spa2297_RS22425 0a48199159ff5f5e328913767c3057aa 294 PANTHER PTHR10459:SF53 126 278 2.4E-12 T 16-09-2016 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 SUPERFAMILY SSF47413 19 85 2.04E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 Pfam PF13560 Helix-turn-helix domain 22 80 1.3E-16 T 16-09-2016 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 SUPERFAMILY SSF51182 86 191 5.4E-22 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 SMART SM00530 25 80 2.2E-16 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 Gene3D G3DSA:2.60.120.10 91 191 1.5E-18 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 PANTHER PTHR10245 22 193 2.8E-32 T 16-09-2016 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 Pfam PF07883 Cupin domain 122 189 3.0E-12 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 PANTHER PTHR10245:SF20 22 193 2.8E-32 T 16-09-2016 Spa2297_RS28205 e51f077067c88c799de48b2730de0fb7 211 Gene3D G3DSA:1.10.260.40 22 90 1.3E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 PANTHER PTHR11075:SF6 5 367 1.2E-140 T 16-09-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 PANTHER PTHR11075 5 367 1.2E-140 T 16-09-2016 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 SUPERFAMILY SSF75620 30 366 2.22E-120 T 16-09-2016 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 Gene3D G3DSA:1.20.58.410 4 115 6.2E-34 T 16-09-2016 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 Gene3D G3DSA:3.30.160.20 227 305 1.6E-35 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 37.672 T 16-09-2016 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 Pfam PF00472 RF-1 domain 228 336 5.1E-38 T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 9.8E-153 T 16-09-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 SMART SM00937 84 194 9.8E-45 T 16-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 Spa2297_RS12850 a0d10fddabba758e0e5b2eb061898556 368 Pfam PF03462 PCRF domain 30 219 2.6E-56 T 16-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 Spa2297_RS19065 c0146341eddbfa573031d8b4cb7a20a7 153 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 22 67 4.3E-7 T 16-09-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.8E-15 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 PANTHER PTHR30146:SF30 2 331 1.4E-108 T 16-09-2016 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 SUPERFAMILY SSF47413 2 60 1.73E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 Gene3D G3DSA:3.40.50.2300 55 171 9.0E-37 T 16-09-2016 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 SMART SM00354 2 72 1.3E-23 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 Pfam PF13377 Periplasmic binding protein-like domain 168 331 3.3E-35 T 16-09-2016 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 Gene3D G3DSA:1.10.260.40 3 54 2.8E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 SUPERFAMILY SSF53822 63 332 4.35E-65 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 PANTHER PTHR30146 2 331 1.4E-108 T 16-09-2016 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 Gene3D G3DSA:3.40.50.2300 172 311 6.3E-48 T 16-09-2016 Spa2297_RS00285 cfc60d96668c2de7236515c1b8a96fc0 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 PANTHER PTHR30328 3 196 2.1E-84 T 16-09-2016 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 Gene3D G3DSA:1.10.357.10 2 193 6.6E-38 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 SUPERFAMILY SSF48498 81 209 6.28E-30 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 PANTHER PTHR30328:SF29 3 196 2.1E-84 T 16-09-2016 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 SUPERFAMILY SSF46689 2 81 4.19E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25600 2b2889aebc59fb0a93d12ba830a74c09 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.2E-18 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 PANTHER PTHR21403:SF0 1 284 9.6E-104 T 16-09-2016 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Gene3D G3DSA:3.40.190.10 1 108 4.3E-32 T 16-09-2016 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Pfam PF08029 HisG, C-terminal domain 210 281 9.1E-26 T 16-09-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Gene3D G3DSA:3.40.190.10 109 174 5.0E-23 T 16-09-2016 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 285 32.231 T 16-09-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 190 284 3.5E-30 T 16-09-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 SUPERFAMILY SSF53850 1 211 2.56E-59 T 16-09-2016 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 SUPERFAMILY SSF54913 213 284 3.45E-21 T 16-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 PANTHER PTHR21403 1 284 9.6E-104 T 16-09-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 8.3E-50 T 16-09-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Pfam PF01634 ATP phosphoribosyltransferase 49 206 2.6E-39 T 16-09-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 Spa2297_RS05410 c2e3301af63563b47e04ef1895b74bfa 285 Gene3D G3DSA:3.30.70.120 213 284 1.0E-28 T 16-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 SMART SM00422 12 82 3.7E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 PANTHER PTHR30204:SF2 4 125 4.3E-26 T 16-09-2016 Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 PANTHER PTHR30204 4 125 4.3E-26 T 16-09-2016 Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 Gene3D G3DSA:1.10.1660.10 12 127 2.2E-26 T 16-09-2016 Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 Pfam PF13411 MerR HTH family regulatory protein 13 80 2.8E-13 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS28770 5496779938660d62839767f95c5e43a3 153 SUPERFAMILY SSF46955 12 128 4.4E-25 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 SUPERFAMILY SSF46894 132 200 4.42E-17 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 PANTHER PTHR26402:SF151 90 200 1.4E-16 T 16-09-2016 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 2.2E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 PANTHER PTHR26402 90 200 1.4E-16 T 16-09-2016 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 SMART SM00421 137 194 2.5E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 Gene3D G3DSA:1.10.10.10 139 200 7.2E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.9E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.9E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS14950 d4506e07ca324c102860189e5bb09ed2 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.9E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24755 d04047c463c680e9ecb8153dcc62e7fe 254 Pfam PF01551 Peptidase family M23 146 237 2.9E-29 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS24755 d04047c463c680e9ecb8153dcc62e7fe 254 Gene3D G3DSA:2.70.70.10 96 248 3.3E-41 T 16-09-2016 Spa2297_RS24755 d04047c463c680e9ecb8153dcc62e7fe 254 PANTHER PTHR21666 64 253 1.3E-40 T 16-09-2016 Spa2297_RS24755 d04047c463c680e9ecb8153dcc62e7fe 254 SUPERFAMILY SSF51261 87 247 1.26E-42 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS07015 bec4b2bd97a747f66f306dc840b061e9 548 PANTHER PTHR33744 18 548 7.1E-235 T 16-09-2016 Spa2297_RS07015 bec4b2bd97a747f66f306dc840b061e9 548 Gene3D G3DSA:1.10.10.60 489 521 1.9E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS07015 bec4b2bd97a747f66f306dc840b061e9 548 PANTHER PTHR33744:SF5 18 548 7.1E-235 T 16-09-2016 Spa2297_RS07015 bec4b2bd97a747f66f306dc840b061e9 548 Pfam PF07905 Purine catabolism regulatory protein-like family 21 141 1.6E-37 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS07015 bec4b2bd97a747f66f306dc840b061e9 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 485 543 2.1E-20 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 PANTHER PTHR30011:SF18 1 435 5.9E-178 T 16-09-2016 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 PANTHER PTHR30011 1 435 5.9E-178 T 16-09-2016 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 PIRSF PIRSF000337 2 441 5.7E-163 T 16-09-2016 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 SUPERFAMILY SSF51679 4 434 1.83E-129 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 Pfam PF00296 Luciferase-like monooxygenase 31 384 3.3E-64 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 428 1.3E-169 T 16-09-2016 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 Gene3D G3DSA:3.20.20.30 346 435 3.2E-136 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS01465 a16597dcaa9c65769b98531ba0b529df 441 Gene3D G3DSA:3.20.20.30 2 304 3.2E-136 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 1.8E-40 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 1.8E-40 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 1.8E-40 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 1.8E-40 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PRINTS PR00069 Aldo-keto reductase signature 34 58 1.8E-40 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 Pfam PF00248 Aldo/keto reductase family 21 257 9.1E-45 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PANTHER PTHR11732 1 283 8.1E-129 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 16-09-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 Gene3D G3DSA:3.20.20.100 2 265 4.2E-92 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 SUPERFAMILY SSF51430 2 265 2.62E-83 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS01865 79e6efd9f12f064e4f3e84f8dc82e84b 283 PANTHER PTHR11732:SF236 1 283 8.1E-129 T 16-09-2016 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 SUPERFAMILY SSF53474 28 312 4.02E-64 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 73 88 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 131 144 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 53 71 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 253 269 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 287 309 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00412 Epoxide hydrolase signature 117 130 4.0E-22 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 Gene3D G3DSA:3.40.50.1820 20 312 4.4E-68 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PANTHER PTHR10992 6 312 1.5E-81 T 16-09-2016 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 Pfam PF12697 Alpha/beta hydrolase family 49 302 8.6E-21 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 3.7E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 131 144 3.7E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 3.7E-5 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS17885 f8fc1bce2cea68a64cb840a95e08853b 317 PANTHER PTHR10992:SF107 6 312 1.5E-81 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 Pfam PF01842 ACT domain 203 258 2.4E-8 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 Pfam PF00800 Prephenate dehydratase 6 183 8.5E-50 T 16-09-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 SUPERFAMILY SSF53850 5 187 9.41E-52 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 Gene3D G3DSA:3.40.190.10 4 92 8.5E-25 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 158 180 - T 16-09-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 PANTHER PTHR21022 3 296 4.6E-98 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 Gene3D G3DSA:3.30.70.260 189 276 2.9E-26 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 PIRSF PIRSF001500 1 278 5.2E-62 T 16-09-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 PANTHER PTHR21022:SF0 3 296 4.6E-98 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 Gene3D G3DSA:3.40.190.10 93 170 9.5E-23 T 16-09-2016 Spa2297_RS16210 59f25a3f8bd37de0a4e7c5cc31c10918 310 SUPERFAMILY SSF55021 177 275 1.2E-21 T 16-09-2016 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 Pfam PF08281 Sigma-70, region 4 121 172 7.0E-11 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 Gene3D G3DSA:1.10.1740.10 5 114 4.8E-34 T 16-09-2016 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 175 2.5E-30 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 SUPERFAMILY SSF88659 99 177 2.99E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 PANTHER PTHR30173:SF24 4 177 2.0E-46 T 16-09-2016 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 Gene3D G3DSA:1.10.10.10 115 176 5.9E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 Pfam PF04542 Sigma-70 region 2 23 89 2.0E-21 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 SUPERFAMILY SSF88946 4 102 7.38E-30 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS26220 8c18e7523eb9188a0868f0894153fed8 180 PANTHER PTHR30173 4 177 2.0E-46 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 PANTHER PTHR35023 426 658 1.0E-140 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 PANTHER PTHR35023 1 364 1.0E-140 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 SMART SM00327 488 665 3.4E-21 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 Pfam PF13519 von Willebrand factor type A domain 491 597 3.1E-17 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 SMART SM00382 29 206 1.1E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 Gene3D G3DSA:1.10.8.80 248 336 5.2E-35 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 6 653 1.8E-255 T 16-09-2016 IPR012804 Cobaltochelatase subunit, putative Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 Gene3D G3DSA:3.40.50.300 5 202 5.8E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 PANTHER PTHR35023:SF1 426 658 1.0E-140 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 PANTHER PTHR35023:SF1 1 364 1.0E-140 T 16-09-2016 Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 SUPERFAMILY SSF53300 491 655 8.07E-24 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 SUPERFAMILY SSF52540 5 331 3.45E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 Pfam PF01078 Magnesium chelatase, subunit ChlI 114 183 1.4E-6 T 16-09-2016 IPR000523 Magnesium chelatase ChlI domain Spa2297_RS07390 b0211cea4fe478c8bce98ca39e4686f3 676 Gene3D G3DSA:3.40.50.410 491 625 4.1E-15 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS23730 2c459b2598fc452ab3288ffa3e9db3aa 261 Gene3D G3DSA:3.40.50.150 6 189 7.2E-14 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS23730 2c459b2598fc452ab3288ffa3e9db3aa 261 SUPERFAMILY SSF53335 4 189 1.86E-16 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 Gene3D G3DSA:3.40.605.10 4 277 5.0E-75 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 SUPERFAMILY SSF53720 4 476 6.81E-130 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 PANTHER PTHR11699:SF108 17 476 3.5E-245 T 16-09-2016 Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 Gene3D G3DSA:3.40.309.10 278 450 8.1E-55 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 Pfam PF00171 Aldehyde dehydrogenase family 16 471 3.0E-132 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS24070 3b89cea5b40dd8467ebcc1b59222850c 481 PANTHER PTHR11699 17 476 3.5E-245 T 16-09-2016 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 3.5E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 3.5E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PANTHER PTHR11751 112 134 1.2E-14 T 16-09-2016 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PANTHER PTHR11751 2 64 1.2E-14 T 16-09-2016 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 Gene3D G3DSA:1.10.10.10 1 63 1.3E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PANTHER PTHR11751:SF358 112 134 1.2E-14 T 16-09-2016 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 PANTHER PTHR11751:SF358 2 64 1.2E-14 T 16-09-2016 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 SUPERFAMILY SSF46785 1 57 1.56E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 55 9.0E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS15245 a68a6f6dc53cc5c4c8a411d1ddc4c3d1 279 SMART SM00345 1 61 1.4E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 PANTHER PTHR10459 5 316 1.1E-38 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 SUPERFAMILY SSF56091 6 200 3.17E-40 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 10 316 2.8E-69 T 16-09-2016 IPR014146 DNA ligase D, ligase domain Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 SUPERFAMILY SSF50249 204 316 9.14E-24 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Gene3D G3DSA:3.30.470.30 33 147 8.0E-26 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Gene3D G3DSA:2.40.50.140 204 316 1.0E-32 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 PANTHER PTHR10459:SF61 5 316 1.1E-38 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Gene3D G3DSA:3.30.1490.70 4 32 2.2E-19 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Gene3D G3DSA:3.30.1490.70 158 201 2.2E-19 T 16-09-2016 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Pfam PF01068 ATP dependent DNA ligase domain 8 200 3.7E-27 T 16-09-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS01950 ef884f068422fef26a858b9a276a4a58 326 Pfam PF04679 ATP dependent DNA ligase C terminal region 223 311 1.1E-20 T 16-09-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 Gene3D G3DSA:1.20.120.350 20 127 1.1E-16 T 16-09-2016 IPR027359 Voltage-dependent channel, four helix bundle domain Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 SUPERFAMILY SSF81324 22 235 1.73E-31 T 16-09-2016 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PRINTS PR00169 Potassium channel signature 58 81 1.6E-7 T 16-09-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PRINTS PR00169 Potassium channel signature 209 235 1.6E-7 T 16-09-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PRINTS PR00169 Potassium channel signature 115 141 1.6E-7 T 16-09-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PRINTS PR00169 Potassium channel signature 16 44 1.6E-7 T 16-09-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PANTHER PTHR10037:SF62 9 242 3.0E-29 T 16-09-2016 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 Pfam PF00520 Ion transport protein 23 240 9.5E-42 T 16-09-2016 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 Spa2297_RS31635 50bbf29cab337b2e5d28b2eaf1248eda 311 PANTHER PTHR10037 9 242 3.0E-29 T 16-09-2016 Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 Pfam PF00266 Aminotransferase class-V 3 372 6.4E-59 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 PIRSF PIRSF005572 1 386 5.8E-104 T 16-09-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 SUPERFAMILY SSF53383 2 381 3.46E-91 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 Gene3D G3DSA:3.90.1150.10 252 376 1.9E-36 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 PANTHER PTHR11601:SF20 1 384 1.1E-136 T 16-09-2016 Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 Gene3D G3DSA:3.40.640.10 22 251 9.3E-71 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS23210 c1618a326a4134e9d755fa4a94a24885 389 PANTHER PTHR11601 1 384 1.1E-136 T 16-09-2016 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 SUPERFAMILY SSF51569 12 305 2.41E-66 T 16-09-2016 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 PANTHER PTHR12128:SF19 1 305 5.6E-144 T 16-09-2016 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 PIRSF PIRSF001365 10 310 7.4E-57 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 PANTHER PTHR12128 1 305 5.6E-144 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 Gene3D G3DSA:3.20.20.70 13 305 6.5E-76 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 Pfam PF00701 Dihydrodipicolinate synthetase family 15 304 6.4E-54 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 8 308 47.357 T 16-09-2016 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501|UniPathway: UPA00564 Spa2297_RS07560 a9ab8fe6366712e46593c45c42752ac1 320 SMART SM01130 12 306 5.9E-74 T 16-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 SUPERFAMILY SSF52821 14 106 3.67E-24 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 Pfam PF00581 Rhodanese-like domain 19 98 2.0E-9 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 Gene3D G3DSA:3.40.250.10 18 105 1.9E-23 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 ProSitePatterns PS00380 Rhodanese signature 1. 30 41 - T 16-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 Pfam PF11127 Protein of unknown function (DUF2892) 116 172 4.5E-10 T 16-09-2016 IPR021309 Protein of unknown function DUF2892 Spa2297_RS03865 4ca4ee5f70a5ac897ebcfac2b97b3182 191 SMART SM00450 5 102 6.5E-16 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 PANTHER PTHR22913 337 389 3.7E-73 T 16-09-2016 IPR026107 Hyaluronan synthase/nodulation protein C Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 PANTHER PTHR22913:SF12 337 389 3.7E-73 T 16-09-2016 Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 Gene3D G3DSA:3.90.550.10 114 377 1.1E-38 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 SUPERFAMILY SSF53448 312 376 3.64E-44 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 SUPERFAMILY SSF53448 113 284 3.64E-44 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 Pfam PF00535 Glycosyl transferase family 2 120 282 2.4E-28 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 PANTHER PTHR22913:SF12 111 311 3.7E-73 T 16-09-2016 Spa2297_RS21390 7207b57c9b52aa7fc0174bb305a605a3 487 PANTHER PTHR22913 111 311 3.7E-73 T 16-09-2016 IPR026107 Hyaluronan synthase/nodulation protein C Spa2297_RS13485 12a01bf5dc5b1acff1f201d5ec36e6d5 256 Pfam PF07510 Protein of unknown function (DUF1524) 117 252 6.7E-13 T 16-09-2016 IPR011089 Domain of unknown function DUF1524 Spa2297_RS13485 12a01bf5dc5b1acff1f201d5ec36e6d5 256 PANTHER PTHR24094:SF10 1 254 1.5E-112 T 16-09-2016 Spa2297_RS13485 12a01bf5dc5b1acff1f201d5ec36e6d5 256 PANTHER PTHR24094 1 254 1.5E-112 T 16-09-2016 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 PANTHER PTHR11986 1 421 5.0E-186 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 Pfam PF00202 Aminotransferase class-III 30 420 8.4E-114 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 PANTHER PTHR11986:SF8 1 421 5.0E-186 T 16-09-2016 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 19 424 2.2E-164 T 16-09-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 Gene3D G3DSA:3.90.1150.10 336 424 9.0E-52 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 Gene3D G3DSA:3.90.1150.10 9 68 9.0E-52 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 Gene3D G3DSA:3.40.640.10 69 329 4.2E-85 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 SUPERFAMILY SSF53383 11 424 1.57E-117 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04540 5d17c81844bebf998f3642b444d4da16 428 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 7 428 49.444 T 16-09-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 PANTHER PTHR35010:SF1 1 273 6.6E-103 T 16-09-2016 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 Pfam PF13560 Helix-turn-helix domain 6 84 7.2E-17 T 16-09-2016 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 SUPERFAMILY SSF47413 29 78 6.68E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 PANTHER PTHR35010 1 273 6.6E-103 T 16-09-2016 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 Gene3D G3DSA:1.10.260.40 4 80 8.5E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31355 8481d92fd4c60e4277e89b812b034395 276 SMART SM00530 9 81 1.2E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 PANTHER PTHR36843:SF1 1 243 1.3E-54 T 16-09-2016 Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 Gene3D G3DSA:3.30.70.1030 29 144 1.0E-28 T 16-09-2016 Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 Gene3D G3DSA:3.30.70.1100 145 242 3.2E-41 T 16-09-2016 Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 PANTHER PTHR36843 1 243 1.3E-54 T 16-09-2016 Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 SUPERFAMILY SSF54909 23 242 9.92E-77 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS25420 39fec173b8b3a7fbbc24a8d6b2b5da58 243 Pfam PF06778 Chlorite dismutase 45 232 9.1E-75 T 16-09-2016 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 PIRSF PIRSF006092 3 164 1.8E-36 T 16-09-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 Gene3D G3DSA:1.10.287.180 7 79 4.3E-27 T 16-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 SUPERFAMILY SSF54534 85 162 6.41E-12 T 16-09-2016 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 Gene3D G3DSA:3.10.50.30 81 163 1.1E-16 T 16-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 5.5E-25 T 16-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 16-09-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 125 141 - T 16-09-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 PANTHER PTHR30437 2 159 9.3E-45 T 16-09-2016 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 28.587 T 16-09-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 2.3E-14 T 16-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 SUPERFAMILY SSF46557 8 81 3.66E-23 T 16-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Spa2297_RS20995 fb0856d16682e49885931f8458c016cd 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 2.0E-47 T 16-09-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 Spa2297_RS29235 e57060f305b44de88496040473c74130 340 PANTHER PTHR10426 113 220 1.1E-14 T 16-09-2016 IPR004141 Strictosidine synthase GO:0009058|GO:0016844 Spa2297_RS29235 e57060f305b44de88496040473c74130 340 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 64 293 4.9E-28 T 16-09-2016 IPR013658 SMP-30/Gluconolactonase/LRE-like region Spa2297_RS29235 e57060f305b44de88496040473c74130 340 Gene3D G3DSA:2.120.10.30 57 335 1.3E-47 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS29235 e57060f305b44de88496040473c74130 340 SUPERFAMILY SSF63829 45 333 8.5E-49 T 16-09-2016 Spa2297_RS08395 d3afd03f1899be4aa1b2170ff101e7d4 246 SMART SM00464 5 222 2.6E-56 T 16-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 Spa2297_RS08395 d3afd03f1899be4aa1b2170ff101e7d4 246 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 4.9E-32 T 16-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 Spa2297_RS08395 d3afd03f1899be4aa1b2170ff101e7d4 246 PANTHER PTHR10046 89 228 4.7E-18 T 16-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 Spa2297_RS08395 d3afd03f1899be4aa1b2170ff101e7d4 246 PANTHER PTHR10046 5 65 4.7E-18 T 16-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 Spa2297_RS08395 d3afd03f1899be4aa1b2170ff101e7d4 246 SUPERFAMILY SSF88697 5 221 7.46E-41 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 Gene3D G3DSA:2.60.40.1180 376 453 6.4E-31 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 SUPERFAMILY SSF51445 34 373 1.55E-84 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 SMART SM00632 380 456 9.4E-37 T 16-09-2016 IPR031319 Alpha-amylase, C-terminal domain Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PANTHER PTHR10357 39 453 2.2E-167 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PRINTS PR00110 Alpha-amylase signature 227 245 1.5E-22 T 16-09-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PRINTS PR00110 Alpha-amylase signature 77 94 1.5E-22 T 16-09-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PRINTS PR00110 Alpha-amylase signature 198 209 1.5E-22 T 16-09-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PRINTS PR00110 Alpha-amylase signature 109 120 1.5E-22 T 16-09-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PRINTS PR00110 Alpha-amylase signature 285 297 1.5E-22 T 16-09-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 Gene3D G3DSA:3.20.20.80 30 375 5.6E-104 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 SMART SM00642 34 371 2.3E-80 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 PANTHER PTHR10357:SF26 39 453 2.2E-167 T 16-09-2016 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 SUPERFAMILY SSF51011 376 454 3.6E-27 T 16-09-2016 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 383 452 3.1E-10 T 16-09-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 Spa2297_RS09300 53f9e0c9beca46d756a004228cabe0d3 458 Pfam PF00128 Alpha amylase, catalytic domain 86 334 5.9E-20 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 SUPERFAMILY SSF46785 14 131 3.55E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 Pfam PF12802 MarR family 19 80 2.5E-12 T 16-09-2016 Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 SMART SM00347 14 116 1.7E-14 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 PANTHER PTHR33164:SF12 12 140 3.1E-22 T 16-09-2016 Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 Gene3D G3DSA:1.10.10.10 14 132 1.3E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00035 958e0f643b3fe19bd41ba0db557e949f 147 PANTHER PTHR33164 12 140 3.1E-22 T 16-09-2016 Spa2297_RS04510 220a71290f6166cd431eb8dce038d7e1 157 Pfam PF00877 NlpC/P60 family 56 142 1.8E-25 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS04510 220a71290f6166cd431eb8dce038d7e1 157 Gene3D G3DSA:3.90.1720.10 38 147 2.3E-38 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS04510 220a71290f6166cd431eb8dce038d7e1 157 PANTHER PTHR21666 32 147 1.6E-27 T 16-09-2016 Spa2297_RS04510 220a71290f6166cd431eb8dce038d7e1 157 SUPERFAMILY SSF54001 41 147 6.87E-36 T 16-09-2016 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.7E-38 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.7E-38 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.7E-38 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 PANTHER PTHR10986 2 124 4.6E-71 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 PANTHER PTHR10986:SF12 2 124 4.6E-71 T 16-09-2016 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 Gene3D G3DSA:1.10.1900.20 56 117 7.2E-31 T 16-09-2016 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 SUPERFAMILY SSF74731 3 117 5.62E-45 T 16-09-2016 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 3.9E-44 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 Pfam PF00453 Ribosomal protein L20 3 109 5.5E-44 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.71 T 16-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS06160 52858a0e9fd9ff0304db466febe62dc3 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-23 T 16-09-2016 Spa2297_RS14230 b5735730a8b9bc80d19c01198599f70d 252 PANTHER PTHR12704 1 88 1.6E-56 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS14230 b5735730a8b9bc80d19c01198599f70d 252 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 1.4E-46 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS14230 b5735730a8b9bc80d19c01198599f70d 252 PANTHER PTHR12704:SF1 1 88 1.6E-56 T 16-09-2016 Spa2297_RS14230 b5735730a8b9bc80d19c01198599f70d 252 Gene3D G3DSA:1.10.3630.10 3 212 3.4E-40 T 16-09-2016 Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 311 1.8E-103 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 SMART SM00382 31 214 1.7E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 PANTHER PTHR24220 8 273 1.8E-100 T 16-09-2016 Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 Pfam PF00005 ABC transporter 22 165 9.8E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 Gene3D G3DSA:3.40.50.300 4 226 3.3E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 SUPERFAMILY SSF52540 7 226 2.25E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 PANTHER PTHR24220:SF0 8 273 1.8E-100 T 16-09-2016 Spa2297_RS14570 efe6046bb496d2fbd88fa8aa5113c2de 326 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS19725 60c2378435f1840bbfea45247c0d19ab 145 Pfam PF13581 Histidine kinase-like ATPase domain 20 117 4.6E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19725 60c2378435f1840bbfea45247c0d19ab 145 SUPERFAMILY SSF55874 43 120 1.34E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19725 60c2378435f1840bbfea45247c0d19ab 145 Gene3D G3DSA:3.30.565.10 48 116 3.5E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18830 6c89620303bb15e20ca6e1e1692a70b9 138 PANTHER PTHR21366:SF13 1 138 2.2E-31 T 16-09-2016 Spa2297_RS18830 6c89620303bb15e20ca6e1e1692a70b9 138 PANTHER PTHR21366 1 138 2.2E-31 T 16-09-2016 Spa2297_RS18830 6c89620303bb15e20ca6e1e1692a70b9 138 SUPERFAMILY SSF54593 1 121 1.61E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS18830 6c89620303bb15e20ca6e1e1692a70b9 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 6.8E-13 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS18830 6c89620303bb15e20ca6e1e1692a70b9 138 Gene3D G3DSA:3.10.180.10 1 121 1.5E-33 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS17780 98a6a16e663ac189f137c14e5243d05e 169 Gene3D G3DSA:2.40.50.140 104 167 6.2E-5 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 Gene3D G3DSA:2.130.10.130 62 217 3.2E-11 T 16-09-2016 Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 Gene3D G3DSA:2.130.10.130 322 421 2.5E-13 T 16-09-2016 Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 SUPERFAMILY SSF69318 63 293 3.66E-32 T 16-09-2016 Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 SUPERFAMILY SSF69318 330 427 3.66E-32 T 16-09-2016 Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 335 395 2.4E-9 T 16-09-2016 Spa2297_RS17465 3d5dd039df38ab6b5ca1f40c9acc7f1e 433 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 131 205 7.7E-7 T 16-09-2016 Spa2297_RS11905 a83c0bfa799cba7cc6a3a5dedc9c134b 482 Gene3D G3DSA:1.25.40.10 250 310 2.8E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11905 a83c0bfa799cba7cc6a3a5dedc9c134b 482 Gene3D G3DSA:1.25.40.10 359 430 2.8E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11905 a83c0bfa799cba7cc6a3a5dedc9c134b 482 SUPERFAMILY SSF48452 368 429 4.99E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11905 a83c0bfa799cba7cc6a3a5dedc9c134b 482 SUPERFAMILY SSF48452 247 319 4.99E-7 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS10575 d0d9039a523617ba08fcc8b8af7d0c45 300 PANTHER PTHR30477:SF0 1 296 8.6E-127 T 16-09-2016 Spa2297_RS10575 d0d9039a523617ba08fcc8b8af7d0c45 300 PANTHER PTHR30477 1 296 8.6E-127 T 16-09-2016 Spa2297_RS10575 d0d9039a523617ba08fcc8b8af7d0c45 300 Gene3D G3DSA:1.10.3470.10 41 262 6.1E-10 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS10575 d0d9039a523617ba08fcc8b8af7d0c45 300 Pfam PF00950 ABC 3 transport family 6 261 1.9E-64 T 16-09-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 Spa2297_RS10575 d0d9039a523617ba08fcc8b8af7d0c45 300 SUPERFAMILY SSF81345 3 259 1.44E-35 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Gene3D G3DSA:3.30.9.10 215 320 8.0E-45 T 16-09-2016 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Gene3D G3DSA:3.30.9.10 62 147 8.0E-45 T 16-09-2016 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 PANTHER PTHR10961 5 373 8.9E-108 T 16-09-2016 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Pfam PF01266 FAD dependent oxidoreductase 6 361 4.2E-43 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Gene3D G3DSA:3.50.50.60 4 59 4.7E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Gene3D G3DSA:3.50.50.60 148 210 4.7E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Gene3D G3DSA:3.50.50.60 324 380 4.7E-52 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 SUPERFAMILY SSF54373 217 320 1.77E-23 T 16-09-2016 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 PANTHER PTHR10961:SF7 5 373 8.9E-108 T 16-09-2016 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 16-09-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 SUPERFAMILY SSF51905 321 380 2.63E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 SUPERFAMILY SSF51905 4 218 2.63E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05220 8e8d4f857678c07ee110672ee41b51a1 389 Hamap MF_00516 Monomeric sarcosine oxidase [soxA]. 1 389 67.687 T 16-09-2016 IPR006281 Sarcosine oxidase, monomeric GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 204 3.3E-73 T 16-09-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PANTHER PTHR23402:SF1 1 213 2.2E-57 T 16-09-2016 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 SUPERFAMILY SSF53182 1 202 6.41E-66 T 16-09-2016 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 Gene3D G3DSA:3.40.630.20 2 202 1.7E-61 T 16-09-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 Pfam PF01470 Pyroglutamyl peptidase 3 198 1.4E-69 T 16-09-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 200 37.06 T 16-09-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PANTHER PTHR23402 1 213 2.2E-57 T 16-09-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 2.2E-45 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 2.2E-45 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 2.2E-45 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 2.2E-45 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 2.2E-45 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS31300 4ca681db83031010d4ea4f494b1a2f04 216 PIRSF PIRSF015592 1 214 1.9E-76 T 16-09-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 Spa2297_RS13970 b3adad84642f6a998dfb71dc725c6cc5 428 PANTHER PTHR41775 2 427 1.8E-141 T 16-09-2016 Spa2297_RS13970 b3adad84642f6a998dfb71dc725c6cc5 428 SUPERFAMILY SSF55486 217 279 7.33E-6 T 16-09-2016 Spa2297_RS13970 b3adad84642f6a998dfb71dc725c6cc5 428 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 92 355 1.0E-52 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS13970 b3adad84642f6a998dfb71dc725c6cc5 428 Gene3D G3DSA:3.40.390.10 199 292 9.9E-8 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 PANTHER PTHR30328 1 213 3.4E-113 T 16-09-2016 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 5.5E-17 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 Gene3D G3DSA:1.10.357.10 12 203 2.8E-44 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 PANTHER PTHR30328:SF28 1 213 3.4E-113 T 16-09-2016 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 SUPERFAMILY SSF46689 11 94 1.5E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS21820 207ba49bd1a3d6822c0bf08e155d7e7f 213 SUPERFAMILY SSF48498 92 204 2.67E-29 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 Gene3D G3DSA:3.30.230.10 10 160 1.3E-58 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PANTHER PTHR20861:SF1 11 308 3.3E-82 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PIRSF PIRSF000676 7 302 3.5E-86 T 16-09-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 TIGRFAM TIGR00191 thrB: homoserine kinase 11 280 2.3E-65 T 16-09-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 SUPERFAMILY SSF55060 173 286 1.09E-27 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 Pfam PF08544 GHMP kinases C terminal 222 279 1.6E-6 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 16-09-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 Gene3D G3DSA:3.30.70.890 171 292 1.7E-34 T 16-09-2016 IPR013750 GHMP kinase, C-terminal domain Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PANTHER PTHR20861 11 308 3.3E-82 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 Pfam PF00288 GHMP kinases N terminal domain 88 151 9.2E-12 T 16-09-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 SUPERFAMILY SSF54211 11 156 3.26E-30 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PRINTS PR00958 Homoserine kinase signature 18 33 7.1E-34 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PRINTS PR00958 Homoserine kinase signature 177 194 7.1E-34 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PRINTS PR00958 Homoserine kinase signature 138 151 7.1E-34 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PRINTS PR00958 Homoserine kinase signature 101 116 7.1E-34 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 PRINTS PR00958 Homoserine kinase signature 254 269 7.1E-34 T 16-09-2016 Spa2297_RS22610 3fab11b7906de531c5337304b0c038e1 309 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.802 T 16-09-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 Pfam PF00296 Luciferase-like monooxygenase 9 305 1.8E-46 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 PANTHER PTHR30137 2 330 3.8E-114 T 16-09-2016 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 10 328 6.5E-106 T 16-09-2016 IPR019949 Luciferase family oxidoreductase, group 1 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 Gene3D G3DSA:3.20.20.30 9 330 1.2E-83 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 SUPERFAMILY SSF51679 9 330 3.27E-70 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS29050 514e5e4e72834375f5a0f918ac88a021 339 PANTHER PTHR30137:SF2 2 330 3.8E-114 T 16-09-2016 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 Pfam PF01565 FAD binding domain 98 229 7.3E-31 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 Gene3D G3DSA:3.30.465.10 155 265 2.2E-12 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 Gene3D G3DSA:3.30.43.10 96 152 2.7E-7 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 PANTHER PTHR11748:SF86 53 528 7.2E-164 T 16-09-2016 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 Pfam PF08031 Berberine and berberine like 485 527 2.0E-11 T 16-09-2016 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 SUPERFAMILY SSF56176 60 265 9.49E-52 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS15505 f90a7e743dfa7286173359f4642a3e68 528 PANTHER PTHR11748 53 528 7.2E-164 T 16-09-2016 Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 SMART SM00862 114 188 1.9E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 PANTHER PTHR26402:SF399 101 191 4.4E-27 T 16-09-2016 Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 SUPERFAMILY SSF46894 102 189 4.64E-27 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 Pfam PF00486 Transcriptional regulatory protein, C terminal 114 187 1.3E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 Gene3D G3DSA:1.10.10.10 101 190 1.3E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09235 fe366eeb4b05631d651b03e992dceac3 194 PANTHER PTHR26402 101 191 4.4E-27 T 16-09-2016 Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 Pfam PF00106 short chain dehydrogenase 35 238 2.1E-27 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 SUPERFAMILY SSF51735 33 285 4.12E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 Gene3D G3DSA:3.40.50.720 26 279 2.0E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 171 7.1E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 7.1E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 117 7.1E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 33 50 7.1E-17 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26050 6a63b2702bd7f828308f738e170963da 326 PANTHER PTHR24320 1 325 2.1E-86 T 16-09-2016 Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 252 5.9E-11 T 16-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 SMART SM00382 30 230 3.0E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 Gene3D G3DSA:3.40.50.300 4 250 3.2E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 Pfam PF00005 ABC transporter 21 181 2.3E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 PANTHER PTHR24220 7 256 4.2E-137 T 16-09-2016 Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 SUPERFAMILY SSF52540 5 253 1.11E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30160 78c0c2770f46a834f18ee4e6cad1f8fd 259 PANTHER PTHR24220:SF519 7 256 4.2E-137 T 16-09-2016 Spa2297_RS06660 6534295828eb65b5e5b8f95dda95618d 104 Pfam PF05360 yiaA/B two helix domain 14 66 2.4E-17 T 16-09-2016 IPR008024 YiaAB two helix Spa2297_RS06660 6534295828eb65b5e5b8f95dda95618d 104 PANTHER PTHR37290:SF1 4 103 4.0E-30 T 16-09-2016 Spa2297_RS06660 6534295828eb65b5e5b8f95dda95618d 104 PANTHER PTHR37290 4 103 4.0E-30 T 16-09-2016 Spa2297_RS02600 f8e8ff45f589eba53ecf87e66ef7bd24 122 SUPERFAMILY SSF52091 7 104 1.44E-17 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02600 f8e8ff45f589eba53ecf87e66ef7bd24 122 Pfam PF13466 STAS domain 13 93 5.2E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02600 f8e8ff45f589eba53ecf87e66ef7bd24 122 Gene3D G3DSA:3.30.750.24 6 99 1.6E-18 T 16-09-2016 IPR002645 STAS domain Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 PANTHER PTHR24023 64 393 4.0E-41 T 16-09-2016 Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 PANTHER PTHR24023:SF593 64 393 4.0E-41 T 16-09-2016 Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 Gene3D G3DSA:3.30.1540.10 233 315 5.8E-25 T 16-09-2016 Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 Gene3D G3DSA:3.40.50.10540 14 226 3.5E-108 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 Gene3D G3DSA:3.40.50.10540 316 406 3.5E-108 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 SUPERFAMILY SSF89796 15 406 2.49E-128 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS08275 629727577d9d460a49856b8681a82f23 406 Pfam PF02515 CoA-transferase family III 16 383 2.1E-123 T 16-09-2016 IPR003673 CoA-transferase family III GO:0003824 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 Gene3D G3DSA:1.10.10.10 1 82 9.8E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 PANTHER PTHR30346 1 294 1.3E-102 T 16-09-2016 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 PANTHER PTHR30346:SF15 1 294 1.3E-102 T 16-09-2016 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 Gene3D G3DSA:3.40.190.10 190 269 8.6E-25 T 16-09-2016 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-11 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-11 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-11 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 SUPERFAMILY SSF53850 90 294 3.33E-43 T 16-09-2016 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-24 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 Gene3D G3DSA:3.40.190.10 88 189 2.3E-27 T 16-09-2016 Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 SUPERFAMILY SSF46785 1 110 2.27E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29010 810eef6ee39e4bfa1ff9e45c21da0e44 294 Pfam PF03466 LysR substrate binding domain 88 293 5.3E-47 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 SUPERFAMILY SSF51679 1 289 4.06E-54 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 274 2.4E-63 T 16-09-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 PANTHER PTHR30011 13 281 4.1E-41 T 16-09-2016 Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 PANTHER PTHR30011:SF5 13 281 4.1E-41 T 16-09-2016 Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 Gene3D G3DSA:3.20.20.30 1 296 2.5E-60 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS25190 877c9751803edf3f64c3c0b052542bf0 300 Pfam PF00296 Luciferase-like monooxygenase 2 263 4.6E-45 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 Gene3D G3DSA:3.20.20.70 27 374 6.8E-131 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 PIRSF PIRSF000138 5 381 3.2E-119 T 16-09-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 Pfam PF01070 FMN-dependent dehydrogenase 35 374 3.1E-123 T 16-09-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 282 288 - T 16-09-2016 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 SUPERFAMILY SSF51395 28 375 1.16E-89 T 16-09-2016 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 PANTHER PTHR10578 10 386 1.2E-197 T 16-09-2016 Spa2297_RS29900 9c90b96e3f8c06c6cbf1fb4a7c08131e 389 PANTHER PTHR10578:SF79 10 386 1.2E-197 T 16-09-2016 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 Gene3D G3DSA:1.20.1250.20 250 432 2.9E-18 T 16-09-2016 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 Gene3D G3DSA:1.20.1250.20 22 222 9.1E-27 T 16-09-2016 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 PANTHER PTHR23508 16 448 3.2E-186 T 16-09-2016 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 Pfam PF00083 Sugar (and other) transporter 21 221 2.0E-27 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 Pfam PF00083 Sugar (and other) transporter 249 416 1.9E-12 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 SUPERFAMILY SSF103473 17 430 6.8E-62 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27660 9f7ff49f0535503cb6d0160207f7a61f 452 PANTHER PTHR23508:SF19 16 448 3.2E-186 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 PANTHER PTHR10366:SF427 306 344 1.7E-95 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 PANTHER PTHR10366 2 252 1.7E-95 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 PANTHER PTHR10366:SF427 2 252 1.7E-95 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 1.1E-32 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 SUPERFAMILY SSF51735 316 344 1.03E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 SUPERFAMILY SSF51735 1 257 1.03E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 PANTHER PTHR10366 306 344 1.7E-95 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 Gene3D G3DSA:3.40.50.720 202 241 3.5E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 Gene3D G3DSA:3.40.50.720 1 160 3.5E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 Gene3D G3DSA:3.90.25.10 188 201 5.9E-5 T 16-09-2016 Spa2297_RS21850 7cc0381db145d0e89d00f03af0253be3 351 Gene3D G3DSA:3.90.25.10 314 343 5.9E-5 T 16-09-2016 Spa2297_RS27400 c1d7324b29b1b588e806ce8222504d89 391 Pfam PF01261 Xylose isomerase-like TIM barrel 51 234 1.1E-12 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27400 c1d7324b29b1b588e806ce8222504d89 391 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 209 216 - T 16-09-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Spa2297_RS27400 c1d7324b29b1b588e806ce8222504d89 391 SUPERFAMILY SSF51658 15 247 1.17E-25 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS27400 c1d7324b29b1b588e806ce8222504d89 391 Gene3D G3DSA:3.20.20.150 14 233 3.5E-18 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS02920 a264804d37f0739447c3b0a18e9f323c 305 PANTHER PTHR20883 18 269 1.6E-26 T 16-09-2016 Spa2297_RS02920 a264804d37f0739447c3b0a18e9f323c 305 Gene3D G3DSA:2.60.120.620 9 264 2.0E-50 T 16-09-2016 Spa2297_RS02920 a264804d37f0739447c3b0a18e9f323c 305 SUPERFAMILY SSF51197 17 269 2.29E-48 T 16-09-2016 Spa2297_RS02920 a264804d37f0739447c3b0a18e9f323c 305 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 28 250 8.2E-20 T 16-09-2016 IPR008775 Phytanoyl-CoA dioxygenase Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 SUPERFAMILY SSF53850 49 569 6.34E-113 T 16-09-2016 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 Gene3D G3DSA:3.90.76.10 62 214 4.8E-34 T 16-09-2016 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 PANTHER PTHR30290:SF29 9 579 6.8E-243 T 16-09-2016 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 PIRSF PIRSF002741 15 572 1.6E-85 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 PANTHER PTHR30290 9 579 6.8E-243 T 16-09-2016 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 Gene3D G3DSA:3.40.190.10 215 330 1.8E-31 T 16-09-2016 Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 470 2.5E-82 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS24210 d51292c22a93cb28c2c20624cf14d909 619 Gene3D G3DSA:3.10.105.10 331 535 2.6E-45 T 16-09-2016 Spa2297_RS29190 795e85996b692bf2bbf8814420770cf9 115 Gene3D G3DSA:1.25.40.10 15 113 1.9E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS29190 795e85996b692bf2bbf8814420770cf9 115 Pfam PF14559 Tetratricopeptide repeat 22 84 2.6E-10 T 16-09-2016 Spa2297_RS29190 795e85996b692bf2bbf8814420770cf9 115 SUPERFAMILY SSF48452 7 111 8.78E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS08855 2f3bfdcc5197b9a22f6f17043b153e1d 352 SUPERFAMILY SSF50022 172 235 6.31E-29 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS08855 2f3bfdcc5197b9a22f6f17043b153e1d 352 SUPERFAMILY SSF50022 269 351 6.31E-29 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS08855 2f3bfdcc5197b9a22f6f17043b153e1d 352 Gene3D G3DSA:2.102.10.10 208 351 8.5E-36 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS08855 2f3bfdcc5197b9a22f6f17043b153e1d 352 Gene3D G3DSA:2.102.10.10 100 129 8.5E-36 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS08855 2f3bfdcc5197b9a22f6f17043b153e1d 352 Pfam PF00355 Rieske [2Fe-2S] domain 261 323 6.9E-9 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS25055 785c711ef4ce674791789ba3782a4ff7 153 Pfam PF07885 Ion channel 60 138 5.8E-15 T 16-09-2016 IPR013099 Potassium channel domain Spa2297_RS25055 785c711ef4ce674791789ba3782a4ff7 153 Gene3D G3DSA:1.10.287.70 37 129 2.5E-16 T 16-09-2016 Spa2297_RS25055 785c711ef4ce674791789ba3782a4ff7 153 SUPERFAMILY SSF81324 35 146 3.4E-19 T 16-09-2016 Spa2297_RS32495 8a3c6016aff99533cbd8a137612dbfb9 328 PANTHER PTHR30193:SF15 161 328 7.3E-53 T 16-09-2016 Spa2297_RS32495 8a3c6016aff99533cbd8a137612dbfb9 328 SUPERFAMILY SSF161098 184 307 2.62E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32495 8a3c6016aff99533cbd8a137612dbfb9 328 PANTHER PTHR30193 161 328 7.3E-53 T 16-09-2016 Spa2297_RS32495 8a3c6016aff99533cbd8a137612dbfb9 328 Gene3D G3DSA:1.10.3720.10 180 319 6.4E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 Gene3D G3DSA:1.20.1250.20 251 453 4.3E-17 T 16-09-2016 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 Gene3D G3DSA:1.20.1250.20 2 186 1.9E-27 T 16-09-2016 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 PANTHER PTHR23501 1 451 2.1E-130 T 16-09-2016 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 PANTHER PTHR23501:SF76 1 451 2.1E-130 T 16-09-2016 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 SUPERFAMILY SSF103473 237 450 9.29E-58 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 SUPERFAMILY SSF103473 1 185 9.29E-58 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 ProSitePatterns PS00216 Sugar transport proteins signature 1. 55 71 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS02570 d006cc37bbc3cbe9f7a10e60ced31770 484 Pfam PF07690 Major Facilitator Superfamily 6 399 5.3E-49 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 Pfam PF00455 DeoR C terminal sensor domain 75 230 8.0E-46 T 16-09-2016 IPR014036 DeoR C-terminal sensor domain Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.0E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.0E-6 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 PANTHER PTHR30363:SF14 1 251 2.9E-126 T 16-09-2016 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 Gene3D G3DSA:1.10.10.10 5 52 5.4E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 SMART SM00420 6 58 2.5E-8 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 PANTHER PTHR30363 1 251 2.9E-126 T 16-09-2016 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.7E-12 T 16-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 SUPERFAMILY SSF46785 1 55 7.4E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 Gene3D G3DSA:3.40.50.1360 76 213 1.9E-10 T 16-09-2016 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 SUPERFAMILY SSF100950 74 234 5.44E-27 T 16-09-2016 Spa2297_RS29370 323ba16c684ab4299a4603b8ddd1852f 252 SMART SM01134 71 232 7.5E-63 T 16-09-2016 Spa2297_RS28500 9c24b0abe02784b1ee93211b5790ff66 137 SUPERFAMILY SSF54593 1 131 9.98E-37 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS28500 9c24b0abe02784b1ee93211b5790ff66 137 PANTHER PTHR33990:SF1 2 134 4.2E-49 T 16-09-2016 Spa2297_RS28500 9c24b0abe02784b1ee93211b5790ff66 137 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 130 1.4E-11 T 16-09-2016 IPR028973 3-demethylubiquinone-9 3-methyltransferase Spa2297_RS28500 9c24b0abe02784b1ee93211b5790ff66 137 Gene3D G3DSA:3.10.180.10 9 134 1.9E-43 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS28500 9c24b0abe02784b1ee93211b5790ff66 137 PANTHER PTHR33990 2 134 4.2E-49 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 SUPERFAMILY SSF53850 74 411 3.78E-61 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PANTHER PTHR30222:SF5 65 414 4.6E-92 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 Gene3D G3DSA:3.40.190.10 206 361 2.3E-41 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 Pfam PF13416 Bacterial extracellular solute-binding protein 99 374 5.7E-29 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 Gene3D G3DSA:3.40.190.10 90 205 3.9E-13 T 16-09-2016 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 165 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 268 287 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 312 331 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 150 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 229 248 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 184 200 4.0E-9 T 16-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spa2297_RS24010 84d4e3afc9388100abfbe6a93cdb310f 415 PANTHER PTHR30222 65 414 4.6E-92 T 16-09-2016 Spa2297_RS12225 1069bbd95df538f4d5c53920ec9b2de5 237 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 25 236 1.4E-32 T 16-09-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Spa2297_RS12225 1069bbd95df538f4d5c53920ec9b2de5 237 Pfam PF02096 60Kd inner membrane protein 26 236 1.6E-30 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS12225 1069bbd95df538f4d5c53920ec9b2de5 237 PANTHER PTHR12428 6 237 1.8E-29 T 16-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 SUPERFAMILY SSF50022 8 134 5.5E-30 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 PANTHER PTHR21266 17 327 1.9E-62 T 16-09-2016 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 Pfam PF11723 Homotrimeric ring hydroxylase 126 196 9.7E-5 T 16-09-2016 IPR021028 Homotrimeric ring hydroxylase, catalytic domain KEGG: 00621+1.14.12.22|MetaCyc: PWY-6550 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 SUPERFAMILY SSF55961 134 330 8.79E-41 T 16-09-2016 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 Pfam PF00355 Rieske [2Fe-2S] domain 20 99 3.9E-14 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 Gene3D G3DSA:2.102.10.10 18 135 1.5E-25 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS11940 89fb2bef90239ccbfb0b821c354ecd53 342 PANTHER PTHR21266:SF23 17 327 1.9E-62 T 16-09-2016 Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 Gene3D G3DSA:3.90.1150.10 264 370 4.8E-21 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 Gene3D G3DSA:3.40.640.10 47 263 4.7E-50 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 PANTHER PTHR11751:SF410 18 375 1.4E-177 T 16-09-2016 Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 Pfam PF00155 Aminotransferase class I and II 77 364 6.8E-26 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 SUPERFAMILY SSF53383 29 370 2.87E-55 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS10140 255475801c98e63b82af617cf20437da 540 PANTHER PTHR11751 18 375 1.4E-177 T 16-09-2016 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 Pfam PF02527 rRNA small subunit methyltransferase G 23 197 1.4E-56 T 16-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 195 1.0E-37 T 16-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 Gene3D G3DSA:3.40.50.150 25 212 1.1E-59 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 PANTHER PTHR31760 12 195 8.8E-58 T 16-09-2016 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 PANTHER PTHR31760:SF0 12 195 8.8E-58 T 16-09-2016 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 194 24.071 T 16-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spa2297_RS16550 3c3f92feed5da3d7b2e67ce3952bfd48 239 SUPERFAMILY SSF53335 22 207 1.5E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS20210 d63d9e536c894b517d00647bf12a210c 469 PANTHER PTHR33885:SF3 6 447 1.0E-188 T 16-09-2016 Spa2297_RS20210 d63d9e536c894b517d00647bf12a210c 469 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 362 427 3.4E-9 T 16-09-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF Spa2297_RS20210 d63d9e536c894b517d00647bf12a210c 469 PANTHER PTHR33885 6 447 1.0E-188 T 16-09-2016 Spa2297_RS20210 d63d9e536c894b517d00647bf12a210c 469 Pfam PF04024 PspC domain 49 104 1.2E-13 T 16-09-2016 IPR007168 Phage shock protein, PspC, N-terminal Spa2297_RS23500 d6d597f7b2974e230049a1eb166af89e 261 Gene3D G3DSA:3.90.850.10 51 259 2.8E-91 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS23500 d6d597f7b2974e230049a1eb166af89e 261 PANTHER PTHR11820 46 260 2.8E-106 T 16-09-2016 Spa2297_RS23500 d6d597f7b2974e230049a1eb166af89e 261 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 3.1E-11 T 16-09-2016 IPR018833 Domain of unknown function DUF2437 Spa2297_RS23500 d6d597f7b2974e230049a1eb166af89e 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 258 3.2E-70 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS23500 d6d597f7b2974e230049a1eb166af89e 261 SUPERFAMILY SSF56529 52 258 6.67E-78 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS06870 735bc714af27f062b2acf811806d74e0 323 PANTHER PTHR30011 58 317 2.1E-21 T 16-09-2016 Spa2297_RS06870 735bc714af27f062b2acf811806d74e0 323 PANTHER PTHR30011:SF18 58 317 2.1E-21 T 16-09-2016 Spa2297_RS06870 735bc714af27f062b2acf811806d74e0 323 SUPERFAMILY SSF51679 17 312 1.02E-54 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06870 735bc714af27f062b2acf811806d74e0 323 Gene3D G3DSA:3.20.20.30 8 313 1.6E-63 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06870 735bc714af27f062b2acf811806d74e0 323 Pfam PF00296 Luciferase-like monooxygenase 22 217 1.2E-24 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 Gene3D G3DSA:3.30.420.40 1 123 5.0E-34 T 16-09-2016 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 Gene3D G3DSA:3.30.420.150 125 306 1.5E-49 T 16-09-2016 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 SUPERFAMILY SSF53067 129 307 9.62E-38 T 16-09-2016 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 Pfam PF02541 Ppx/GppA phosphatase family 26 305 1.3E-71 T 16-09-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 PANTHER PTHR30005 1 308 1.8E-93 T 16-09-2016 Spa2297_RS18440 65b0729c9e16ef6e2d77ee84ec626847 310 SUPERFAMILY SSF53067 2 125 1.77E-30 T 16-09-2016 Spa2297_RS05275 533bf0dec59e5bab158bbe83cb28f328 286 Gene3D G3DSA:3.40.50.1110 3 189 5.0E-31 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS05275 533bf0dec59e5bab158bbe83cb28f328 286 PANTHER PTHR30383 5 186 4.9E-34 T 16-09-2016 Spa2297_RS05275 533bf0dec59e5bab158bbe83cb28f328 286 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 181 2.3E-23 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS05275 533bf0dec59e5bab158bbe83cb28f328 286 SUPERFAMILY SSF52266 2 191 1.02E-34 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS05275 533bf0dec59e5bab158bbe83cb28f328 286 PANTHER PTHR30383:SF8 5 186 4.9E-34 T 16-09-2016 Spa2297_RS26600 8b06a496574c9d8d54343acec6d4597b 651 Gene3D G3DSA:3.50.50.60 5 193 9.5E-11 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26600 8b06a496574c9d8d54343acec6d4597b 651 Pfam PF13454 FAD-NAD(P)-binding 10 191 2.9E-46 T 16-09-2016 Spa2297_RS26600 8b06a496574c9d8d54343acec6d4597b 651 SUPERFAMILY SSF51905 4 249 8.74E-9 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03840 bd3f860996453da9ff811bc17d52f0be 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 328 3.4E-33 T 16-09-2016 IPR005064 Bordetella uptake gene GO:0030288 Spa2297_RS03840 bd3f860996453da9ff811bc17d52f0be 328 PANTHER PTHR30349 1 323 7.4E-117 T 16-09-2016 Spa2297_RS03840 bd3f860996453da9ff811bc17d52f0be 328 PANTHER PTHR30349:SF25 1 323 7.4E-117 T 16-09-2016 Spa2297_RS03840 bd3f860996453da9ff811bc17d52f0be 328 SUPERFAMILY SSF53850 122 299 1.17E-8 T 16-09-2016 Spa2297_RS03840 bd3f860996453da9ff811bc17d52f0be 328 PIRSF PIRSF017082 3 328 3.9E-97 T 16-09-2016 IPR005064 Bordetella uptake gene GO:0030288 Spa2297_RS22500 dbde77cedbf909fb78b9718cf93e06b4 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 4.0E-10 T 16-09-2016 Spa2297_RS22500 dbde77cedbf909fb78b9718cf93e06b4 146 SUPERFAMILY SSF54593 3 143 2.2E-30 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS22500 dbde77cedbf909fb78b9718cf93e06b4 146 Gene3D G3DSA:3.10.180.10 1 144 4.2E-50 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 Pfam PF00120 Glutamine synthetase, catalytic domain 138 463 3.2E-76 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 PANTHER PTHR20852:SF16 41 478 2.1E-153 T 16-09-2016 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 Gene3D G3DSA:3.30.590.10 141 463 2.3E-88 T 16-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 SUPERFAMILY SSF54368 38 136 2.49E-5 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 SMART SM01230 137 389 5.1E-82 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 PANTHER PTHR20852 41 478 2.1E-153 T 16-09-2016 Spa2297_RS28370 7bf6e6b8acc8d3a4e35052c1e75027da 479 SUPERFAMILY SSF55931 137 467 3.53E-82 T 16-09-2016 Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 Pfam PF15608 PELOTA RNA binding domain 729 808 4.9E-34 T 16-09-2016 IPR028157 PELOTA RNA-binding domain KEGG: 00900+3.4.22.- Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 Pfam PF15609 Phosphoribosyl transferase 36 223 4.3E-70 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 SUPERFAMILY SSF53271 37 207 1.26E-7 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 Pfam PF12500 TRSP domain C terminus to PRTase_2 275 412 2.0E-48 T 16-09-2016 IPR022537 TRSP domain Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 Pfam PF11202 Phosphoribosyl transferase (PRTase) 452 702 2.4E-106 T 16-09-2016 IPR011215 Phosphoribosyl transferase KEGG: 00900+3.4.22.- Spa2297_RS09930 23fe534e7583ee41b5c8657dee588055 825 Gene3D G3DSA:3.40.50.2020 88 199 1.8E-5 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS08165 3e028d865f37c08c27ba813918010398 310 PANTHER PTHR11795:SF371 2 309 7.4E-121 T 16-09-2016 Spa2297_RS08165 3e028d865f37c08c27ba813918010398 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 294 3.7E-45 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS08165 3e028d865f37c08c27ba813918010398 310 PANTHER PTHR11795 2 309 7.4E-121 T 16-09-2016 Spa2297_RS11535 462bd39fc65fa88190eee3ca87d9faf6 485 PANTHER PTHR11785 34 466 4.7E-91 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS11535 462bd39fc65fa88190eee3ca87d9faf6 485 PIRSF PIRSF006060 14 479 1.1E-58 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS11535 462bd39fc65fa88190eee3ca87d9faf6 485 PANTHER PTHR11785:SF261 34 466 4.7E-91 T 16-09-2016 Spa2297_RS11535 462bd39fc65fa88190eee3ca87d9faf6 485 Pfam PF13520 Amino acid permease 39 432 2.9E-34 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 Gene3D G3DSA:3.30.420.40 173 321 1.0E-50 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 SUPERFAMILY SSF53067 38 349 4.93E-69 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 PANTHER PTHR18964 17 232 2.2E-112 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 PANTHER PTHR18964:SF108 17 232 2.2E-112 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 Gene3D G3DSA:3.30.420.40 38 172 1.1E-43 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 PANTHER PTHR18964:SF108 252 348 2.2E-112 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 PANTHER PTHR18964 252 348 2.2E-112 T 16-09-2016 Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 ProSitePatterns PS01125 ROK family signature. 167 194 - T 16-09-2016 IPR000600 ROK family Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 Pfam PF00480 ROK family 38 348 4.9E-79 T 16-09-2016 IPR000600 ROK family Spa2297_RS26505 94498a8c8dc7cb45f2838f1f0341c55e 382 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 39 348 6.2E-91 T 16-09-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 Gene3D G3DSA:3.20.20.100 2 317 1.5E-59 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 PANTHER PTHR11732 1 92 1.4E-122 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 PANTHER PTHR11732:SF208 110 317 1.4E-122 T 16-09-2016 Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 SUPERFAMILY SSF51430 2 317 3.4E-66 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 PANTHER PTHR11732 110 317 1.4E-122 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 PANTHER PTHR11732:SF208 1 92 1.4E-122 T 16-09-2016 Spa2297_RS32115 f3f26bf3abd8b7e61cb14cab08530707 337 Pfam PF00248 Aldo/keto reductase family 14 316 2.2E-49 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS20275 05ee8006706bfc740e6ea5b1adb89b62 377 PANTHER PTHR22908 59 313 9.9E-129 T 16-09-2016 Spa2297_RS20275 05ee8006706bfc740e6ea5b1adb89b62 377 PANTHER PTHR22908:SF67 59 313 9.9E-129 T 16-09-2016 Spa2297_RS20275 05ee8006706bfc740e6ea5b1adb89b62 377 SUPERFAMILY SSF52540 73 278 1.46E-21 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20275 05ee8006706bfc740e6ea5b1adb89b62 377 Pfam PF07728 AAA domain (dynein-related subfamily) 95 233 6.7E-36 T 16-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Spa2297_RS20275 05ee8006706bfc740e6ea5b1adb89b62 377 Gene3D G3DSA:3.40.50.300 76 245 2.1E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PANTHER PTHR13789 3 360 1.7E-87 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 SUPERFAMILY SSF51905 264 360 1.73E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 SUPERFAMILY SSF51905 6 171 1.73E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PANTHER PTHR13789:SF186 3 360 1.7E-87 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 Gene3D G3DSA:3.50.50.60 265 335 5.7E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 Gene3D G3DSA:3.50.50.60 6 176 5.7E-38 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 8.9E-22 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 8.9E-22 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.9E-22 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 8.9E-22 T 16-09-2016 Spa2297_RS04895 b5638013934b5ce22c7bb12652112a91 391 Pfam PF01494 FAD binding domain 7 310 9.9E-23 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 PANTHER PTHR34384:SF4 401 602 3.4E-267 T 16-09-2016 Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 Pfam PF04183 IucA / IucC family 148 377 4.7E-65 T 16-09-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 PANTHER PTHR34384:SF4 20 382 3.4E-267 T 16-09-2016 Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 PANTHER PTHR34384 20 382 3.4E-267 T 16-09-2016 Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 Pfam PF06276 Ferric iron reductase FhuF-like transporter 424 585 7.7E-30 T 16-09-2016 IPR022770 Ferric iron reductase FhuF domain Spa2297_RS24555 e6636d8743f02f5599f9f160768540ea 604 PANTHER PTHR34384 401 602 3.4E-267 T 16-09-2016 Spa2297_RS01220 274591b41d6f0330347a088f5459a0b5 299 PANTHER PTHR32243:SF25 29 298 7.4E-184 T 16-09-2016 Spa2297_RS01220 274591b41d6f0330347a088f5459a0b5 299 SUPERFAMILY SSF161098 28 295 2.49E-70 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01220 274591b41d6f0330347a088f5459a0b5 299 Gene3D G3DSA:1.10.3720.10 29 285 3.2E-67 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01220 274591b41d6f0330347a088f5459a0b5 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 290 2.8E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01220 274591b41d6f0330347a088f5459a0b5 299 PANTHER PTHR32243 29 298 7.4E-184 T 16-09-2016 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 PANTHER PTHR11839 2 177 1.8E-42 T 16-09-2016 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 Pfam PF00293 NUDIX domain 41 152 1.7E-17 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 PANTHER PTHR11839:SF9 2 177 1.8E-42 T 16-09-2016 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 SUPERFAMILY SSF55811 3 174 2.03E-38 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS06130 d7dcc7f48b854fd32939d78951762e50 187 Gene3D G3DSA:3.90.79.10 2 173 1.9E-36 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS20185 c70d5fea4ddb3c3e7faecde9ec2ef179 169 PANTHER PTHR35176 16 167 7.1E-64 T 16-09-2016 Spa2297_RS20185 c70d5fea4ddb3c3e7faecde9ec2ef179 169 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 115 3.5E-5 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS20185 c70d5fea4ddb3c3e7faecde9ec2ef179 169 PANTHER PTHR35176:SF1 16 167 7.1E-64 T 16-09-2016 Spa2297_RS20185 c70d5fea4ddb3c3e7faecde9ec2ef179 169 Gene3D G3DSA:2.30.110.10 28 142 7.5E-19 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS20185 c70d5fea4ddb3c3e7faecde9ec2ef179 169 SUPERFAMILY SSF50475 27 152 5.7E-18 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS30485 4cafa6eaa006fad72e42b241b83db436 194 PANTHER PTHR32097 1 193 1.4E-54 T 16-09-2016 Spa2297_RS30485 4cafa6eaa006fad72e42b241b83db436 194 PANTHER PTHR32097:SF7 1 193 1.4E-54 T 16-09-2016 Spa2297_RS30485 4cafa6eaa006fad72e42b241b83db436 194 Pfam PF02342 TerD domain 14 175 1.7E-17 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS30485 4cafa6eaa006fad72e42b241b83db436 194 Gene3D G3DSA:2.60.60.30 15 188 5.1E-33 T 16-09-2016 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 PANTHER PTHR19211 316 536 4.4E-103 T 16-09-2016 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 PANTHER PTHR19211 12 289 4.4E-103 T 16-09-2016 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 Gene3D G3DSA:3.40.50.300 382 536 2.3E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 Gene3D G3DSA:3.40.50.300 14 266 4.8E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 Pfam PF00005 ABC transporter 27 196 1.0E-26 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 Pfam PF00005 ABC transporter 381 508 1.0E-16 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 SUPERFAMILY SSF52540 135 242 8.69E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 SUPERFAMILY SSF52540 11 102 8.69E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 SUPERFAMILY SSF52540 382 538 5.91E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 SMART SM00382 36 241 1.2E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11370 2f3ebd3cd9e431ca3223219a060b8ec2 554 SMART SM00382 386 552 6.1E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 Pfam PF00487 Fatty acid desaturase 63 278 3.5E-21 T 16-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 222 243 1.6E-16 T 16-09-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 265 279 1.6E-16 T 16-09-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 62 84 1.6E-16 T 16-09-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PRINTS PR00075 Fatty acid desaturase family 1 signature 85 105 1.6E-16 T 16-09-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PANTHER PTHR11351:SF3 5 331 4.0E-182 T 16-09-2016 Spa2297_RS13580 e13ef220ddac0e3f7e4cbb1345bc5fe6 336 PANTHER PTHR11351 5 331 4.0E-182 T 16-09-2016 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 SMART SM00411 1 89 4.6E-38 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 PANTHER PTHR33175 1 101 3.1E-46 T 16-09-2016 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 Gene3D G3DSA:4.10.520.10 1 89 6.9E-27 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 SUPERFAMILY SSF47729 1 92 4.27E-24 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 Pfam PF00216 Bacterial DNA-binding protein 1 88 1.9E-22 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 PANTHER PTHR33175:SF3 1 101 3.1E-46 T 16-09-2016 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 16-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 4.5E-13 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 4.5E-13 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS23560 7dc176944211b8bb738c478f11b77db1 217 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 4.5E-13 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS01895 85e8244566622c4cae74e42b988671e1 510 Pfam PF13556 PucR C-terminal helix-turn-helix domain 338 379 6.9E-10 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS01895 85e8244566622c4cae74e42b988671e1 510 Pfam PF13556 PucR C-terminal helix-turn-helix domain 428 485 1.6E-9 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 Gene3D G3DSA:3.90.226.10 278 535 6.3E-102 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 106 120 4.5E-5 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 140 158 4.5E-5 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 Gene3D G3DSA:3.90.226.10 7 267 2.9E-85 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 Pfam PF01039 Carboxyl transferase domain 39 533 6.1E-198 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 PANTHER PTHR22855 10 535 0.0 T 16-09-2016 Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 SUPERFAMILY SSF52096 17 267 9.95E-82 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 PANTHER PTHR22855:SF14 10 535 0.0 T 16-09-2016 Spa2297_RS20850 d445f04d2cb16bb4be878c18eb1880ad 535 SUPERFAMILY SSF52096 254 535 5.39E-89 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 SUPERFAMILY SSF52096 265 527 1.55E-88 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 SUPERFAMILY SSF52096 13 267 9.33E-74 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 PANTHER PTHR22855 17 527 0.0 T 16-09-2016 Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 PANTHER PTHR22855:SF14 17 527 0.0 T 16-09-2016 Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 Gene3D G3DSA:3.90.226.10 270 526 6.5E-101 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 Gene3D G3DSA:3.90.226.10 20 269 5.0E-76 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23445 3c3326f94057245358be8f9fe07b6127 527 Pfam PF01039 Carboxyl transferase domain 40 524 2.7E-198 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 5.2E-27 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 PIRSF PIRSF016578 5 389 3.0E-15 T 16-09-2016 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 PANTHER PTHR10909:SF305 1 386 1.6E-184 T 16-09-2016 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Gene3D G3DSA:1.10.540.10 15 125 2.5E-26 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 2.4E-21 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 9.4E-51 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 SUPERFAMILY SSF47203 234 386 1.77E-59 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 PANTHER PTHR10909 1 386 1.6E-184 T 16-09-2016 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Gene3D G3DSA:2.40.110.10 129 223 1.3E-40 T 16-09-2016 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 SUPERFAMILY SSF56645 13 249 5.63E-73 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS05365 68ca1bbafb45fd2d559a9d2248d75dd0 390 Gene3D G3DSA:1.20.140.10 224 386 2.1E-72 T 16-09-2016 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 285 305 3.5E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 3.5E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 325 348 3.5E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 306 323 3.5E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 349 363 3.5E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 SUPERFAMILY SSF50494 208 377 1.32E-33 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 334 345 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 Gene3D G3DSA:2.40.10.10 283 371 3.5E-30 T 16-09-2016 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 Gene3D G3DSA:3.30.300.50 41 124 8.0E-28 T 16-09-2016 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 Gene3D G3DSA:3.30.300.50 125 192 2.3E-16 T 16-09-2016 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 Pfam PF02983 Alpha-lytic protease prodomain 126 183 4.1E-9 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 Gene3D G3DSA:2.40.10.10 203 282 1.3E-25 T 16-09-2016 Spa2297_RS01775 94786606201594d720e059e79dd7fffc 386 PIRSF PIRSF001134 3 386 1.1E-128 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 PRINTS PR01021 OMPA domain signature 103 125 6.7E-7 T 16-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 PRINTS PR01021 OMPA domain signature 148 164 6.7E-7 T 16-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 PRINTS PR01021 OMPA domain signature 133 148 6.7E-7 T 16-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 SUPERFAMILY SSF103088 92 204 2.09E-28 T 16-09-2016 IPR006665 OmpA-like domain Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 Pfam PF00691 OmpA family 103 198 2.2E-15 T 16-09-2016 IPR006665 OmpA-like domain Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 Gene3D G3DSA:3.30.1330.60 86 204 1.8E-29 T 16-09-2016 IPR006665 OmpA-like domain Spa2297_RS21210 97960f02f8f120db39cb1454af7327ab 209 PANTHER PTHR30128 52 208 3.8E-32 T 16-09-2016 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 Gene3D G3DSA:3.40.630.30 185 346 1.1E-54 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 SUPERFAMILY SSF55729 184 366 6.37E-44 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 PANTHER PTHR36174:SF1 1 122 1.0E-146 T 16-09-2016 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 PANTHER PTHR36174 139 373 1.0E-146 T 16-09-2016 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 PANTHER PTHR36174 1 122 1.0E-146 T 16-09-2016 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 PANTHER PTHR36174:SF1 139 373 1.0E-146 T 16-09-2016 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 Gene3D G3DSA:3.40.630.30 5 116 3.5E-50 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 Gene3D G3DSA:3.40.630.30 148 184 3.5E-50 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 SUPERFAMILY SSF55729 7 114 2.6E-33 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 SUPERFAMILY SSF55729 143 191 2.6E-33 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 Pfam PF02388 FemAB family 8 250 3.4E-30 T 16-09-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 Spa2297_RS30640 99c6a6b3f9699cdc1c2eb9400972d8d0 373 Pfam PF02388 FemAB family 268 366 4.5E-19 T 16-09-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 Spa2297_RS02540 e2a3f02e3bd3284e1ab91263ff5dc41d 378 PANTHER PTHR38479:SF2 2 359 1.6E-46 T 16-09-2016 Spa2297_RS02540 e2a3f02e3bd3284e1ab91263ff5dc41d 378 PANTHER PTHR38479 2 359 1.6E-46 T 16-09-2016 Spa2297_RS02540 e2a3f02e3bd3284e1ab91263ff5dc41d 378 Pfam PF06224 Winged helix DNA-binding domain 30 347 1.8E-62 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 SMART SM01003 4 137 7.9E-80 T 16-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 PIRSF PIRSF000183 1 371 6.6E-165 T 16-09-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.6E-79 T 16-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 PANTHER PTHR10160 2 370 3.9E-199 T 16-09-2016 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 Gene3D G3DSA:3.40.50.1770 190 357 7.4E-28 T 16-09-2016 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 7.0E-48 T 16-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 16-09-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 SUPERFAMILY SSF52283 305 360 4.34E-67 T 16-09-2016 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 SUPERFAMILY SSF52283 2 137 4.34E-67 T 16-09-2016 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 SUPERFAMILY SSF51735 137 303 3.31E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 SMART SM01002 149 297 1.1E-81 T 16-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 Gene3D G3DSA:3.40.50.1770 2 189 1.1E-61 T 16-09-2016 Spa2297_RS06990 49d97cb8e779330e3feec9978899100f 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 1.3E-169 T 16-09-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 SUPERFAMILY SSF46548 124 233 4.19E-19 T 16-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 Gene3D G3DSA:3.10.20.30 5 96 1.7E-28 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 54 62 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 Pfam PF13183 4Fe-4S dicluster domain 141 222 1.3E-14 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 PANTHER PTHR11921 1 254 2.6E-182 T 16-09-2016 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 Gene3D G3DSA:1.10.1060.10 97 244 2.7E-19 T 16-09-2016 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 19 225 2.1E-42 T 16-09-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 PANTHER PTHR11921:SF10 1 254 2.6E-182 T 16-09-2016 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 105 1.3E-24 T 16-09-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 Spa2297_RS21530 c82929728e4f18aa0814c2eecd4f2182 255 SUPERFAMILY SSF54292 4 104 1.7E-21 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS26135 c9b520a3a930a3034f63236d54d54f5d 108 SUPERFAMILY SSF57716 75 106 7.7E-7 T 16-09-2016 Spa2297_RS26135 c9b520a3a930a3034f63236d54d54f5d 108 PANTHER PTHR33823 41 106 1.4E-20 T 16-09-2016 Spa2297_RS26135 c9b520a3a930a3034f63236d54d54f5d 108 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 73 106 8.8E-12 T 16-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PANTHER PTHR19139:SF100 1 274 1.6E-103 T 16-09-2016 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 158 176 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 95 114 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 191 213 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 240 260 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 12 31 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PRINTS PR00783 Major intrinsic protein family signature 58 82 5.3E-46 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 Gene3D G3DSA:1.20.1080.10 6 269 3.5E-79 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 Pfam PF00230 Major intrinsic protein 7 257 1.2E-50 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 ProSitePatterns PS00221 MIP family signature. 76 84 - T 16-09-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 PANTHER PTHR19139 1 274 1.6E-103 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 SUPERFAMILY SSF81338 11 261 2.35E-65 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS31025 7eb4d0e140b5066407a123f5f61af3f5 281 TIGRFAM TIGR00861 MIP: MIP family channel proteins 16 257 3.4E-62 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS24600 9e2c318c97ea1cfedc6608fc9db76174 301 PANTHER PTHR16222:SF12 1 295 1.9E-52 T 16-09-2016 Spa2297_RS24600 9e2c318c97ea1cfedc6608fc9db76174 301 SUPERFAMILY SSF101478 10 297 9.42E-50 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS24600 9e2c318c97ea1cfedc6608fc9db76174 301 Pfam PF03747 ADP-ribosylglycohydrolase 18 276 5.3E-43 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS24600 9e2c318c97ea1cfedc6608fc9db76174 301 PANTHER PTHR16222 1 295 1.9E-52 T 16-09-2016 Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 SUPERFAMILY SSF50249 6 200 2.94E-41 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 Pfam PF00436 Single-strand binding protein family 7 107 2.7E-30 T 16-09-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 PANTHER PTHR10302 7 164 1.2E-32 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 124 1.2E-29 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 Gene3D G3DSA:2.40.50.140 4 116 2.5E-41 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS16435 b2894710c28a7bc1f91328879c20d9fb 200 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.404 T 16-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 Gene3D G3DSA:3.30.465.10 53 164 7.2E-34 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 SMART SM01092 171 281 5.7E-18 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 279 7.2E-11 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 Gene3D G3DSA:3.30.43.10 2 51 1.9E-14 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 164 3.4E-46 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 PANTHER PTHR11908 1 283 4.5E-112 T 16-09-2016 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 Gene3D G3DSA:3.30.390.50 172 283 4.4E-32 T 16-09-2016 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 SUPERFAMILY SSF55447 172 284 6.8E-19 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 SUPERFAMILY SSF56176 2 164 8.41E-49 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS26165 2b34dfdef531080c85687565bd305246 296 PANTHER PTHR11908:SF68 1 283 4.5E-112 T 16-09-2016 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 PANTHER PTHR30136 363 601 4.6E-83 T 16-09-2016 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SUPERFAMILY SSF55781 93 240 1.11E-19 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SUPERFAMILY SSF46785 31 100 2.07E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Pfam PF01614 Bacterial transcriptional regulator 518 583 2.9E-15 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:3.30.450.40 521 591 1.2E-18 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:3.30.450.40 97 237 3.8E-44 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:3.30.450.40 437 520 3.6E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:3.30.450.40 293 340 3.8E-44 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:1.10.10.10 26 96 1.7E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Gene3D G3DSA:1.10.10.10 362 434 6.7E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SUPERFAMILY SSF46785 366 435 4.09E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SUPERFAMILY SSF55781 432 589 4.02E-33 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 PANTHER PTHR30136:SF10 363 601 4.6E-83 T 16-09-2016 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SMART SM00346 366 455 2.8E-22 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 SMART SM00346 28 117 9.7E-10 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Pfam PF09339 IclR helix-turn-helix domain 368 416 3.2E-11 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS13975 e951b6d6b74925c9754bc2d3edde47f3 601 Pfam PF09339 IclR helix-turn-helix domain 31 82 3.5E-11 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS09085 cde5fbf4701271c68ac57ef4bfe18054 234 Pfam PF13829 Domain of unknown function (DUF4191) 11 227 1.8E-85 T 16-09-2016 IPR025445 Protein of unknown function DUF4191 Spa2297_RS09085 cde5fbf4701271c68ac57ef4bfe18054 234 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 1 210 3.0E-87 T 16-09-2016 Spa2297_RS10520 307ad5ed00b7c1bbf72d8feef590a4ea 400 Pfam PF01757 Acyltransferase family 48 370 6.7E-27 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS10520 307ad5ed00b7c1bbf72d8feef590a4ea 400 PANTHER PTHR23028 19 389 1.8E-197 T 16-09-2016 Spa2297_RS10520 307ad5ed00b7c1bbf72d8feef590a4ea 400 PANTHER PTHR23028:SF79 19 389 1.8E-197 T 16-09-2016 Spa2297_RS26240 5f1fd0371ad0f386c8c600de372ea582 292 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 34 287 2.0E-26 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS26240 5f1fd0371ad0f386c8c600de372ea582 292 Pfam PF03631 Virulence factor BrkB 36 289 4.2E-52 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS26240 5f1fd0371ad0f386c8c600de372ea582 292 PANTHER PTHR30213:SF2 22 289 1.9E-44 T 16-09-2016 Spa2297_RS26240 5f1fd0371ad0f386c8c600de372ea582 292 PANTHER PTHR30213 22 289 1.9E-44 T 16-09-2016 Spa2297_RS26240 5f1fd0371ad0f386c8c600de372ea582 292 PIRSF PIRSF035875 12 292 3.4E-57 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS02615 002c28f158e987ae6dd544c36c399ef9 124 SUPERFAMILY SSF52091 6 112 1.33E-16 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02615 002c28f158e987ae6dd544c36c399ef9 124 Pfam PF13466 STAS domain 21 97 3.5E-12 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02615 002c28f158e987ae6dd544c36c399ef9 124 Gene3D G3DSA:3.30.750.24 6 115 2.4E-19 T 16-09-2016 IPR002645 STAS domain Spa2297_RS00300 4500ccd08ef3b248dce34c3cbcfdc6bd 106 Pfam PF12680 SnoaL-like domain 9 90 2.3E-11 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS00300 4500ccd08ef3b248dce34c3cbcfdc6bd 106 Gene3D G3DSA:3.10.450.50 2 103 1.5E-12 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS00300 4500ccd08ef3b248dce34c3cbcfdc6bd 106 SUPERFAMILY SSF54427 2 105 3.0E-15 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 PANTHER PTHR18964:SF123 58 388 3.5E-121 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 PANTHER PTHR18964 58 388 3.5E-121 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 Gene3D G3DSA:1.10.10.10 10 74 4.2E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 Gene3D G3DSA:3.30.420.40 77 219 1.6E-44 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 SUPERFAMILY SSF53067 79 383 2.64E-60 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 ProSitePatterns PS01125 ROK family signature. 215 242 - T 16-09-2016 IPR000600 ROK family Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 Pfam PF12802 MarR family 17 68 1.3E-8 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 SUPERFAMILY SSF46785 12 71 2.02E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 Gene3D G3DSA:3.30.420.40 220 360 2.6E-49 T 16-09-2016 Spa2297_RS25260 8a70e3490478d6f9ae1a9dcd8932b5e6 403 Pfam PF00480 ROK family 82 378 7.3E-60 T 16-09-2016 IPR000600 ROK family Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.89 T 16-09-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 Gene3D G3DSA:3.20.20.70 5 238 8.9E-73 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 Pfam PF00977 Histidine biosynthesis protein 6 231 4.2E-64 T 16-09-2016 IPR006062 Histidine biosynthesis GO:0000105 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 SUPERFAMILY SSF51366 4 237 1.02E-64 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 1.0E-117 T 16-09-2016 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 PANTHER PTHR21235:SF15 1 239 2.1E-92 T 16-09-2016 Spa2297_RS08360 1982e8aac29dd611ce867a7bf776c3b6 241 PANTHER PTHR21235 1 239 2.1E-92 T 16-09-2016 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PANTHER PTHR10992 12 178 5.7E-145 T 16-09-2016 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PANTHER PTHR10992 222 333 5.7E-145 T 16-09-2016 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PRINTS PR00412 Epoxide hydrolase signature 118 131 9.4E-28 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PRINTS PR00412 Epoxide hydrolase signature 104 117 9.4E-28 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PRINTS PR00412 Epoxide hydrolase signature 308 330 9.4E-28 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PRINTS PR00412 Epoxide hydrolase signature 38 56 9.4E-28 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PRINTS PR00412 Epoxide hydrolase signature 58 73 9.4E-28 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 SUPERFAMILY SSF53474 10 196 1.17E-63 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 SUPERFAMILY SSF53474 226 332 1.17E-63 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 Pfam PF00561 alpha/beta hydrolase fold 32 319 1.2E-24 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 Gene3D G3DSA:3.40.50.1820 4 194 1.4E-80 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 Gene3D G3DSA:3.40.50.1820 226 332 1.4E-80 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PANTHER PTHR10992:SF305 12 178 5.7E-145 T 16-09-2016 Spa2297_RS17850 d158a877e6896676ce49dfc8bc3359c3 336 PANTHER PTHR10992:SF305 222 333 5.7E-145 T 16-09-2016 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PANTHER PTHR11353 1 535 6.3E-218 T 16-09-2016 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 Gene3D G3DSA:1.10.560.10 369 518 1.4E-37 T 16-09-2016 IPR027413 GroEL-like equatorial domain Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 SUPERFAMILY SSF48592 6 133 2.33E-72 T 16-09-2016 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 SUPERFAMILY SSF48592 406 521 2.33E-72 T 16-09-2016 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 16-09-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 Gene3D G3DSA:1.10.560.10 6 186 6.5E-44 T 16-09-2016 IPR027413 GroEL-like equatorial domain Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 3.6E-91 T 16-09-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.557 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 1.0E-244 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 Gene3D G3DSA:3.50.7.10 187 368 2.9E-95 T 16-09-2016 IPR027409 GroEL-like apical domain Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 SUPERFAMILY SSF54849 136 202 1.63E-24 T 16-09-2016 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 SUPERFAMILY SSF52029 184 376 3.84E-80 T 16-09-2016 IPR027409 GroEL-like apical domain Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PRINTS PR00298 60kDa chaperonin signature 268 291 4.5E-72 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PRINTS PR00298 60kDa chaperonin signature 350 375 4.5E-72 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PRINTS PR00298 60kDa chaperonin signature 26 52 4.5E-72 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PRINTS PR00298 60kDa chaperonin signature 398 419 4.5E-72 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS20085 e97078aa30fe10d4af64821b83cd6558 541 PRINTS PR00298 60kDa chaperonin signature 82 109 4.5E-72 T 16-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 SUPERFAMILY SSF55811 12 149 3.93E-33 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.9E-5 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.9E-5 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 PANTHER PTHR22769 4 207 3.5E-83 T 16-09-2016 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 Gene3D G3DSA:1.10.10.10 149 222 1.3E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 PANTHER PTHR22769:SF42 4 207 3.5E-83 T 16-09-2016 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 Pfam PF00293 NUDIX domain 21 138 3.7E-20 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 Gene3D G3DSA:3.90.79.10 3 142 2.7E-50 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06960 a3d4d0a0d544d9090bb063bf95142fcc 239 SUPERFAMILY SSF46785 155 228 1.82E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 269 332 1.6E-40 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 440 514 1.6E-40 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 617 768 1.6E-32 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.90.1170.50 146 268 5.9E-43 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 SUPERFAMILY SSF56003 272 902 1.7E-175 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:1.10.150.120 72 145 7.6E-26 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Pfam PF01799 [2Fe-2S] binding domain 70 139 4.3E-25 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 315 842 3.1E-147 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 56 9.5E-5 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 SUPERFAMILY SSF47741 82 146 3.93E-24 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 SUPERFAMILY SSF54665 149 299 7.85E-44 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 PANTHER PTHR11908 149 906 1.9E-288 T 16-09-2016 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 769 901 1.1E-53 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 517 616 1.1E-53 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 SUPERFAMILY SSF54292 2 75 9.57E-20 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.30.365.10 333 436 1.7E-36 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 SMART SM01008 168 280 5.2E-50 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 PANTHER PTHR11908:SF96 149 906 1.9E-288 T 16-09-2016 Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Gene3D G3DSA:3.10.20.30 2 71 9.1E-26 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS17230 14cc97c051d247fda47264a9d883a6bb 906 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 168 280 3.0E-29 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 SUPERFAMILY SSF52540 475 512 1.17E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 SUPERFAMILY SSF52540 227 434 1.17E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 4.5E-47 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.046 T 16-09-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 16-09-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 Gene3D G3DSA:3.40.50.300 218 439 6.2E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 SMART SM00382 265 419 1.2E-22 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 2.1E-251 T 16-09-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 4.0E-52 T 16-09-2016 IPR032501 Proteasomal ATPase, OB/ID domain Spa2297_RS06390 3af9a4b6aee98063349a4ec5e4029571 588 PANTHER PTHR23077 220 444 1.3E-87 T 16-09-2016 Spa2297_RS10150 d697e66d4c3c1413df7de953b4a5ff0a 259 PANTHER PTHR37042:SF2 3 258 1.2E-65 T 16-09-2016 Spa2297_RS10150 d697e66d4c3c1413df7de953b4a5ff0a 259 PANTHER PTHR37042 3 258 1.2E-65 T 16-09-2016 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 PIRSF PIRSF007663 22 801 3.2E-301 T 16-09-2016 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 SUPERFAMILY SSF48208 293 775 7.37E-89 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 PANTHER PTHR31084 18 795 0.0 T 16-09-2016 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 PANTHER PTHR31084:SF4 18 795 0.0 T 16-09-2016 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 Gene3D G3DSA:2.70.98.50 52 422 2.0E-140 T 16-09-2016 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 Spa2297_RS32150 9a2de08c917c0798698f3677809750e6 809 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 53 289 2.8E-74 T 16-09-2016 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 Spa2297_RS22815 e8e3ec308eef3fd4b336b98f865459e1 1304 PANTHER PTHR38010 624 1304 1.2E-98 T 16-09-2016 Spa2297_RS22815 e8e3ec308eef3fd4b336b98f865459e1 1304 SUPERFAMILY SSF58113 847 1002 1.11E-5 T 16-09-2016 Spa2297_RS22815 e8e3ec308eef3fd4b336b98f865459e1 1304 PANTHER PTHR38010:SF1 624 1304 1.2E-98 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:1.10.8.280 154 258 7.6E-9 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 SMART SM00382 476 716 0.69 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 SMART SM00382 25 413 2.1 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:3.40.50.300 457 512 7.8E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:3.40.50.300 634 752 7.8E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:3.40.50.300 327 443 2.7E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:3.40.50.300 5 79 2.7E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Pfam PF00005 ABC transporter 467 670 1.1E-9 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:1.20.1580.10 259 326 8.8E-33 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:1.20.1580.10 516 633 1.1E-34 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 Gene3D G3DSA:1.20.1580.10 94 153 8.8E-33 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 SUPERFAMILY SSF52540 465 721 3.66E-35 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 PANTHER PTHR32282:SF10 2 748 0.0 T 16-09-2016 Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 SUPERFAMILY SSF52540 201 418 1.63E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 SUPERFAMILY SSF52540 9 54 1.63E-33 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02630 914cbcb033a26857012205af7ad33cf7 756 PANTHER PTHR32282 2 748 0.0 T 16-09-2016 Spa2297_RS14725 6142aae4e7391098fecad019541ca090 219 Gene3D G3DSA:1.10.3210.10 36 192 1.2E-12 T 16-09-2016 IPR006674 HD domain Spa2297_RS14725 6142aae4e7391098fecad019541ca090 219 PANTHER PTHR21174 1 219 3.0E-50 T 16-09-2016 IPR009218 Predicted HD phosphohydrolase Spa2297_RS14725 6142aae4e7391098fecad019541ca090 219 PIRSF PIRSF035170 1 214 2.1E-83 T 16-09-2016 IPR009218 Predicted HD phosphohydrolase Spa2297_RS14725 6142aae4e7391098fecad019541ca090 219 SUPERFAMILY SSF109604 27 201 2.08E-34 T 16-09-2016 Spa2297_RS26315 1810e2a29260d0905bacb6e1f99ad9a2 122 PANTHER PTHR35568 1 121 2.7E-36 T 16-09-2016 Spa2297_RS26315 1810e2a29260d0905bacb6e1f99ad9a2 122 Pfam PF13309 HTH domain 56 117 5.5E-20 T 16-09-2016 Spa2297_RS29360 62ab0ae77a1bc1e9b8ececa85512dc77 137 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 126 3.4E-6 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS29360 62ab0ae77a1bc1e9b8ececa85512dc77 137 Gene3D G3DSA:3.30.530.20 4 108 4.0E-7 T 16-09-2016 IPR023393 START-like domain Spa2297_RS29360 62ab0ae77a1bc1e9b8ececa85512dc77 137 SUPERFAMILY SSF55961 1 133 1.12E-13 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 PANTHER PTHR10617 14 324 6.4E-25 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 Gene3D G3DSA:3.30.9.10 165 318 1.1E-22 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 3.5E-14 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.5E-14 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 3.5E-14 T 16-09-2016 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 Gene3D G3DSA:3.40.50.720 106 164 8.2E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 Gene3D G3DSA:3.40.50.720 12 64 8.2E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 Pfam PF01494 FAD binding domain 13 57 6.0E-8 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 Pfam PF01494 FAD binding domain 116 328 2.4E-7 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 SUPERFAMILY SSF51905 270 337 7.56E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14115 6ed67702a1ac640c01f0ef939ad22d04 383 SUPERFAMILY SSF51905 12 175 7.56E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 SUPERFAMILY SSF53067 96 224 1.12E-13 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 Gene3D G3DSA:3.30.420.40 94 238 4.6E-23 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 Pfam PF00480 ROK family 109 399 2.1E-32 T 16-09-2016 IPR000600 ROK family Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 PANTHER PTHR18964 74 408 1.7E-100 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 Gene3D G3DSA:3.30.420.40 239 385 1.0E-33 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 PANTHER PTHR18964:SF108 74 408 1.7E-100 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 SUPERFAMILY SSF53067 228 407 4.38E-32 T 16-09-2016 Spa2297_RS03470 7be5fd1490728a918c3e8063aa8afefd 412 Gene3D G3DSA:1.10.10.10 31 91 2.8E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 SUPERFAMILY SSF47819 626 705 6.98E-19 T 16-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Pfam PF00580 UvrD/REP helicase N-terminal domain 158 266 5.8E-26 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 92 6.0E-21 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 PANTHER PTHR11070 1 567 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 PANTHER PTHR11070:SF21 1 567 0.0 T 16-09-2016 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 SUPERFAMILY SSF52540 3 567 3.16E-121 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Pfam PF00570 HRDC domain 637 702 1.1E-19 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Pfam PF13361 UvrD-like helicase C-terminal domain 440 547 2.0E-23 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Pfam PF13361 UvrD-like helicase C-terminal domain 275 398 4.8E-14 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Gene3D G3DSA:3.40.50.300 4 272 3.6E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Gene3D G3DSA:3.40.50.300 484 567 3.8E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Gene3D G3DSA:3.40.50.300 279 392 3.8E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Gene3D G3DSA:3.30.60.20 602 631 5.6E-4 T 16-09-2016 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 SMART SM00341 633 713 1.1E-13 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS21910 5339b78abb9587a51d922d4e4e013e27 715 Gene3D G3DSA:1.10.150.80 636 700 2.1E-12 T 16-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 86 315 5.7E-6 T 16-09-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 PRINTS PR00738 Glycosyl hydrolase family 20 signature 80 97 1.0E-6 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 PRINTS PR00738 Glycosyl hydrolase family 20 signature 110 131 1.0E-6 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 PRINTS PR00738 Glycosyl hydrolase family 20 signature 47 67 1.0E-6 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 Gene3D G3DSA:3.30.379.10 23 71 3.3E-8 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 SUPERFAMILY SSF55545 7 71 8.37E-8 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 SUPERFAMILY SSF51445 336 429 2.63E-46 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 SUPERFAMILY SSF51445 86 307 2.63E-46 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 PANTHER PTHR22600 27 316 1.9E-12 T 16-09-2016 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 26 68 2.7E-6 T 16-09-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS31480 0ebfb76bb9f2d3b57b6fa0a1457fbeba 600 Gene3D G3DSA:3.20.20.80 84 431 3.0E-28 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 PANTHER PTHR32332 106 361 7.4E-133 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 Gene3D G3DSA:3.20.20.70 2 332 1.3E-68 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 SUPERFAMILY SSF51412 99 348 5.95E-60 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 SUPERFAMILY SSF51412 9 72 5.95E-60 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 PANTHER PTHR32332 1 79 7.4E-133 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 PANTHER PTHR32332:SF12 1 79 7.4E-133 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 PANTHER PTHR32332:SF12 106 361 7.4E-133 T 16-09-2016 Spa2297_RS10750 381ef87eba06b1c06a2e34724dbc0a32 361 Pfam PF03060 Nitronate monooxygenase 3 343 2.3E-123 T 16-09-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 Spa2297_RS06985 4dc3b78e431b78ea9ba807014d23529f 333 PANTHER PTHR13696 71 330 1.4E-116 T 16-09-2016 Spa2297_RS06985 4dc3b78e431b78ea9ba807014d23529f 333 Pfam PF13614 AAA domain 79 254 3.5E-62 T 16-09-2016 IPR025669 AAA domain Spa2297_RS06985 4dc3b78e431b78ea9ba807014d23529f 333 SUPERFAMILY SSF52540 78 330 5.43E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06985 4dc3b78e431b78ea9ba807014d23529f 333 Gene3D G3DSA:3.40.50.300 79 330 4.4E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06985 4dc3b78e431b78ea9ba807014d23529f 333 PANTHER PTHR13696:SF78 71 330 1.4E-116 T 16-09-2016 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 3.9E-81 T 16-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 SUPERFAMILY SSF51366 12 257 2.71E-77 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 16-09-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.856 T 16-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 PANTHER PTHR22854:SF2 2 258 3.9E-103 T 16-09-2016 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 PANTHER PTHR22854 2 258 3.9E-103 T 16-09-2016 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 Gene3D G3DSA:3.20.20.70 2 259 2.4E-94 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08305 3becdd6b5fb0a9e50bebe05d29ca8cda 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.661 T 16-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS22740 d7549725cd1dcf220badb4f9060ee309 249 PANTHER PTHR30294 1 245 4.4E-38 T 16-09-2016 Spa2297_RS22740 d7549725cd1dcf220badb4f9060ee309 249 Pfam PF01061 ABC-2 type transporter 10 212 6.1E-26 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS22740 d7549725cd1dcf220badb4f9060ee309 249 PIRSF PIRSF006648 2 248 7.0E-41 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 SMART SM00382 52 237 7.2E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 PANTHER PTHR24220:SF193 16 326 1.1E-104 T 16-09-2016 Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 Gene3D G3DSA:3.40.50.300 14 257 1.1E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 PANTHER PTHR24220 16 326 1.1E-104 T 16-09-2016 Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 Pfam PF00005 ABC transporter 44 187 6.3E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12365 466706dbd3389f7b1467800987ab79e3 331 SUPERFAMILY SSF52540 38 254 1.81E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 PANTHER PTHR24220:SF0 295 311 7.1E-96 T 16-09-2016 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 PANTHER PTHR24220:SF0 7 228 7.1E-96 T 16-09-2016 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 306 2.5E-98 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 SMART SM00382 30 213 3.7E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 Gene3D G3DSA:3.40.50.300 3 229 4.2E-68 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 PANTHER PTHR24220 295 311 7.1E-96 T 16-09-2016 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 PANTHER PTHR24220 7 228 7.1E-96 T 16-09-2016 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 Pfam PF00005 ABC transporter 21 164 4.0E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS18120 e1aae65cfd0c45b26384fd76588dc757 313 SUPERFAMILY SSF52540 5 225 4.2E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31295 6e9f709049a9b099d899a469f03d5727 324 Pfam PF06166 Protein of unknown function (DUF979) 5 324 2.0E-116 T 16-09-2016 IPR009323 Protein of unknown function DUF979 Spa2297_RS22230 d87320b853a962883645c8365e829125 194 SUPERFAMILY SSF53597 2 193 9.42E-27 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS22230 d87320b853a962883645c8365e829125 194 Pfam PF01872 RibD C-terminal domain 2 187 1.9E-10 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS22230 d87320b853a962883645c8365e829125 194 Gene3D G3DSA:3.40.430.10 3 193 2.7E-28 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS22230 d87320b853a962883645c8365e829125 194 PANTHER PTHR38011 2 194 2.7E-15 T 16-09-2016 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 SUPERFAMILY SSF142695 18 187 1.83E-59 T 16-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 16 211 41.131 T 16-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 Pfam PF00925 GTP cyclohydrolase II 20 185 7.4E-63 T 16-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 PANTHER PTHR21327:SF6 18 216 9.2E-91 T 16-09-2016 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 PANTHER PTHR21327 18 216 9.2E-91 T 16-09-2016 Spa2297_RS27650 bea5c5d4c4daa01a9ace577b32bb9d43 220 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 24 209 9.8E-64 T 16-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 2 410 63.599 T 16-09-2016 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695|UniPathway: UPA00540 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 4 410 1.7E-210 T 16-09-2016 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695|UniPathway: UPA00540 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 Gene3D G3DSA:3.30.1540.10 235 319 1.1E-23 T 16-09-2016 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 PANTHER PTHR24023 59 212 4.9E-28 T 16-09-2016 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 Pfam PF02515 CoA-transferase family III 6 386 6.4E-103 T 16-09-2016 IPR003673 CoA-transferase family III GO:0003824 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 PANTHER PTHR24023 238 397 4.9E-28 T 16-09-2016 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 SUPERFAMILY SSF89796 4 410 1.31E-119 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 Gene3D G3DSA:3.40.50.10540 3 215 8.2E-105 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 Gene3D G3DSA:3.40.50.10540 320 410 8.2E-105 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 PANTHER PTHR24023:SF593 238 397 4.9E-28 T 16-09-2016 Spa2297_RS27425 c077f99bcfa9f5aa3457a4d31ac42abe 410 PANTHER PTHR24023:SF593 59 212 4.9E-28 T 16-09-2016 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 Gene3D G3DSA:1.10.10.10 12 83 1.3E-19 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 Gene3D G3DSA:3.40.1410.10 92 245 1.4E-33 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 SMART SM00345 21 80 3.1E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 SUPERFAMILY SSF46785 13 84 3.67E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 2.1E-14 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PANTHER PTHR11751 184 206 1.1E-12 T 16-09-2016 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 SMART SM00866 101 241 2.3E-18 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PANTHER PTHR11751 9 83 1.1E-12 T 16-09-2016 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 SUPERFAMILY SSF64288 68 247 5.5E-34 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PANTHER PTHR11751:SF333 9 83 1.1E-12 T 16-09-2016 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 2.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 2.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 Pfam PF07702 UTRA domain 105 240 9.8E-27 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS06740 623d04757f6c9310a583d82fefcc71bd 249 PANTHER PTHR11751:SF333 184 206 1.1E-12 T 16-09-2016 Spa2297_RS16275 8373f9f8485d245f137c0ef3eb4aeaad 347 Gene3D G3DSA:2.70.70.10 207 341 2.2E-41 T 16-09-2016 Spa2297_RS16275 8373f9f8485d245f137c0ef3eb4aeaad 347 Pfam PF01551 Peptidase family M23 239 336 5.7E-29 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS16275 8373f9f8485d245f137c0ef3eb4aeaad 347 SUPERFAMILY SSF51261 144 340 1.62E-43 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS16275 8373f9f8485d245f137c0ef3eb4aeaad 347 PANTHER PTHR21666 46 346 8.4E-73 T 16-09-2016 Spa2297_RS16275 8373f9f8485d245f137c0ef3eb4aeaad 347 PANTHER PTHR21666:SF200 46 346 8.4E-73 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SUPERFAMILY SSF158472 283 331 1.83E-7 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 Gene3D G3DSA:3.30.565.10 413 568 3.1E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423:SF500 656 691 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423 656 691 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423 36 73 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 Pfam PF00672 HAMP domain 264 331 5.4E-13 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SMART SM00304 283 335 1.1E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SUPERFAMILY SSF47384 326 410 4.71E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 Pfam PF00512 His Kinase A (phospho-acceptor) domain 343 410 6.3E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423:SF500 277 570 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SMART SM00388 343 410 3.0E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 1.4E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 506 1.4E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 520 1.4E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 564 1.4E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 566 2.7E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SUPERFAMILY SSF55874 400 569 3.01E-39 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423 277 570 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 PANTHER PTHR24423:SF500 36 73 2.3E-239 T 16-09-2016 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 Gene3D G3DSA:1.10.287.130 334 406 1.1E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13010 dea5b8c94f549598e73e2f66957d5f75 693 SMART SM00387 456 567 5.3E-28 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 Gene3D G3DSA:3.40.50.1000 79 199 6.2E-42 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 Gene3D G3DSA:1.10.150.240 19 78 2.6E-4 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 5.5E-6 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 5.5E-6 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 5.5E-6 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 5.5E-6 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 PANTHER PTHR18901 9 191 8.0E-59 T 16-09-2016 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 43 189 2.4E-20 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 SUPERFAMILY SSF56784 9 197 2.48E-52 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS03760 e395c602197bafc87f75f96843588470 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 189 1.0E-33 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 PANTHER PTHR18964:SF109 298 467 1.2E-56 T 16-09-2016 Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 PIRSF PIRSF026713 1 552 5.4E-281 T 16-09-2016 IPR016847 Mannose-6-phosphate isomerase, Firmicutes, long form, predicted Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 SUPERFAMILY SSF51182 202 438 5.59E-52 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 SUPERFAMILY SSF51182 465 537 5.59E-52 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 PANTHER PTHR18964 298 467 1.2E-56 T 16-09-2016 Spa2297_RS00350 efe7b059a9f7af58a2aac1117a53e796 552 Gene3D G3DSA:2.60.120.10 202 437 7.5E-36 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 PANTHER PTHR30011 12 339 5.3E-170 T 16-09-2016 Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 Pfam PF00296 Luciferase-like monooxygenase 17 320 7.2E-78 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 SUPERFAMILY SSF51679 1 339 1.44E-69 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 9.9E-116 T 16-09-2016 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 Gene3D G3DSA:3.20.20.30 1 339 8.2E-75 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06495 32a6f5740cc09fc4b271ba9c28856046 351 PANTHER PTHR30011:SF4 12 339 5.3E-170 T 16-09-2016 Spa2297_RS09000 82eabfb21efb69dc59a7a5fb478743ec 267 Pfam PF03537 Glycoside-hydrolase family GH114 46 260 1.1E-84 T 16-09-2016 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain Spa2297_RS09000 82eabfb21efb69dc59a7a5fb478743ec 267 PANTHER PTHR35273 37 267 7.8E-100 T 16-09-2016 Spa2297_RS09000 82eabfb21efb69dc59a7a5fb478743ec 267 SUPERFAMILY SSF51445 37 252 4.95E-50 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09000 82eabfb21efb69dc59a7a5fb478743ec 267 PANTHER PTHR35273:SF2 37 267 7.8E-100 T 16-09-2016 Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.4E-6 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.4E-6 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 Gene3D G3DSA:3.90.79.10 13 162 1.6E-27 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 SUPERFAMILY SSF55811 13 142 7.99E-22 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 PANTHER PTHR22769 18 108 3.5E-16 T 16-09-2016 Spa2297_RS23780 4f7a0484c8548809a787d41e836c8eac 176 Pfam PF00293 NUDIX domain 17 143 3.5E-22 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 3.0E-36 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.671 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 SUPERFAMILY SSF53098 2 156 8.04E-45 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 3.7E-35 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.7E-35 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 3.7E-35 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 3.7E-35 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 3.7E-35 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 PANTHER PTHR30194 1 171 8.5E-66 T 16-09-2016 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.2E-53 T 16-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 Gene3D G3DSA:3.30.420.10 1 156 3.2E-55 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS05760 f52fa13405d06a6744522cec9f2288b1 191 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 16-09-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 Gene3D G3DSA:3.90.1150.10 258 392 1.1E-38 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 Gene3D G3DSA:3.40.640.10 52 257 3.5E-38 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 PANTHER PTHR11751 16 391 2.0E-235 T 16-09-2016 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 PANTHER PTHR11751:SF142 16 391 2.0E-235 T 16-09-2016 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 Pfam PF00155 Aminotransferase class I and II 77 386 3.1E-32 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS30050 8fa483a2f6c8eebf49d278e2645907e3 405 SUPERFAMILY SSF53383 29 392 9.76E-75 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:3.20.20.60 547 892 1.2E-124 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:1.20.80.30 110 196 7.9E-31 T 16-09-2016 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 446 457 - T 16-09-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Pfam PF00391 PEP-utilising enzyme, mobile domain 418 500 8.1E-23 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:3.30.470.20 242 339 6.9E-34 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 PANTHER PTHR22931 1 645 0.0 T 16-09-2016 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 PANTHER PTHR22931 663 899 0.0 T 16-09-2016 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 PIRSF PIRSF000853 1 897 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 891 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 SUPERFAMILY SSF52009 383 509 2.62E-32 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 PANTHER PTHR22931:SF9 1 645 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 PANTHER PTHR22931:SF9 663 899 0.0 T 16-09-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 SUPERFAMILY SSF56059 1 374 1.53E-128 T 16-09-2016 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 535 887 2.2E-83 T 16-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:1.10.189.10 340 396 5.9E-20 T 16-09-2016 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:3.30.1490.20 3 109 2.6E-53 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:3.30.1490.20 198 241 2.6E-53 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 54 6.7E-10 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 299 349 5.0E-9 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 60 285 2.3E-28 T 16-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 Gene3D G3DSA:3.50.30.10 397 503 7.6E-36 T 16-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spa2297_RS03910 d553a31d8bc664af8e3d1a916f7792dc 900 SUPERFAMILY SSF51621 538 890 3.77E-111 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 PIRSF PIRSF002599 1 67 3.9E-25 T 16-09-2016 IPR012156 Cold shock, CspA GO:0003676 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.0E-28 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-17 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 16-09-2016 IPR019844 Cold-shock conserved site Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 PANTHER PTHR11544 1 67 2.3E-37 T 16-09-2016 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 Gene3D G3DSA:2.40.50.140 1 66 2.2E-29 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 SMART SM00357 3 67 1.2E-29 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS17195 e2eeda2fc4c362e3eb21fb38d7adfc60 67 SUPERFAMILY SSF50249 1 66 8.08E-24 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS29675 d1395161a3676855f9e60c14de05cd74 106 PANTHER PTHR34389 1 105 1.0E-52 T 16-09-2016 Spa2297_RS29675 d1395161a3676855f9e60c14de05cd74 106 Pfam PF05336 Domain of unknown function (DUF718) 3 105 1.2E-30 T 16-09-2016 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UniPathway: UPA00125 Spa2297_RS29675 d1395161a3676855f9e60c14de05cd74 106 PANTHER PTHR34389:SF2 1 105 1.0E-52 T 16-09-2016 Spa2297_RS29675 d1395161a3676855f9e60c14de05cd74 106 SUPERFAMILY SSF54909 1 105 2.15E-33 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 PANTHER PTHR12526 162 402 2.5E-72 T 16-09-2016 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 SUPERFAMILY SSF53756 1 390 5.5E-63 T 16-09-2016 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 Pfam PF00534 Glycosyl transferases group 1 217 369 1.7E-24 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 PANTHER PTHR12526:SF374 162 402 2.5E-72 T 16-09-2016 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 PANTHER PTHR12526 1 127 2.5E-72 T 16-09-2016 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 Pfam PF13439 Glycosyltransferase Family 4 19 203 2.0E-15 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 PANTHER PTHR12526:SF374 1 127 2.5E-72 T 16-09-2016 Spa2297_RS31765 b99bdd19679869c7aa00ceca06bf53bd 413 Gene3D G3DSA:3.40.50.2000 216 369 1.7E-26 T 16-09-2016 Spa2297_RS09240 b52b0cecf7cd57fc13be7fc21e43509c 343 PANTHER PTHR10366:SF430 2 324 2.0E-76 T 16-09-2016 Spa2297_RS09240 b52b0cecf7cd57fc13be7fc21e43509c 343 Pfam PF13460 NAD(P)H-binding 7 135 1.4E-7 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09240 b52b0cecf7cd57fc13be7fc21e43509c 343 Gene3D G3DSA:3.40.50.720 1 240 2.7E-24 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09240 b52b0cecf7cd57fc13be7fc21e43509c 343 PANTHER PTHR10366 2 324 2.0E-76 T 16-09-2016 Spa2297_RS09240 b52b0cecf7cd57fc13be7fc21e43509c 343 SUPERFAMILY SSF51735 1 297 2.12E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07750 67aef05845b046604f99d48855aa8d60 394 Pfam PF01458 Uncharacterized protein family (UPF0051) 144 364 7.3E-71 T 16-09-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Spa2297_RS07750 67aef05845b046604f99d48855aa8d60 394 PANTHER PTHR30508 27 393 1.3E-103 T 16-09-2016 Spa2297_RS07750 67aef05845b046604f99d48855aa8d60 394 PANTHER PTHR30508:SF0 27 393 1.3E-103 T 16-09-2016 Spa2297_RS07750 67aef05845b046604f99d48855aa8d60 394 SUPERFAMILY SSF101960 37 390 6.54E-93 T 16-09-2016 Spa2297_RS07750 67aef05845b046604f99d48855aa8d60 394 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 112 381 2.1E-75 T 16-09-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 SUPERFAMILY SSF46929 147 199 7.72E-10 T 16-09-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Pfam PF07499 RuvA, C-terminal domain 148 197 3.1E-11 T 16-09-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Gene3D G3DSA:2.40.50.140 1 64 1.2E-22 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 PANTHER PTHR33796 2 200 2.5E-73 T 16-09-2016 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Gene3D G3DSA:1.10.150.20 66 131 5.3E-26 T 16-09-2016 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 198 26.829 T 16-09-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Pfam PF01330 RuvA N terminal domain 1 61 3.0E-19 T 16-09-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 SMART SM00278 72 91 50.0 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 SMART SM00278 107 126 0.05 T 16-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Gene3D G3DSA:1.10.8.10 145 201 7.7E-12 T 16-09-2016 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 SUPERFAMILY SSF47781 65 132 8.9E-19 T 16-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.3E-15 T 16-09-2016 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 180 3.3E-38 T 16-09-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Spa2297_RS05755 62769eeed1960a48bec275d4450f0955 201 SUPERFAMILY SSF50249 1 62 4.85E-14 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS21420 15ce513845aeb6b76c63ec49ff025d6f 335 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 7 290 36.897 T 16-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 Spa2297_RS21420 15ce513845aeb6b76c63ec49ff025d6f 335 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 9 287 1.4E-96 T 16-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 Spa2297_RS21420 15ce513845aeb6b76c63ec49ff025d6f 335 Pfam PF02401 LytB protein 9 286 1.7E-88 T 16-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 Spa2297_RS21420 15ce513845aeb6b76c63ec49ff025d6f 335 PANTHER PTHR30426 7 320 2.8E-150 T 16-09-2016 Spa2297_RS17315 8054e7d851ac9af2f0b55652cbbdc7bd 228 Pfam PF11010 Protein of unknown function (DUF2848) 24 218 4.8E-77 T 16-09-2016 IPR021269 Protein of unknown function DUF2848 Spa2297_RS17315 8054e7d851ac9af2f0b55652cbbdc7bd 228 Gene3D G3DSA:3.90.850.10 19 38 8.3E-6 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS17315 8054e7d851ac9af2f0b55652cbbdc7bd 228 Gene3D G3DSA:3.90.850.10 92 204 8.3E-6 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS17315 8054e7d851ac9af2f0b55652cbbdc7bd 228 SUPERFAMILY SSF56529 51 192 4.97E-8 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 SUPERFAMILY SSF47240 39 282 8.92E-83 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 Pfam PF05138 Phenylacetic acid catabolic protein 29 303 6.0E-103 T 16-09-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 PANTHER PTHR30458:SF0 16 325 7.2E-172 T 16-09-2016 Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 Gene3D G3DSA:1.20.1260.10 29 283 4.0E-103 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 PANTHER PTHR30458 16 325 7.2E-172 T 16-09-2016 Spa2297_RS01380 282334a06fd397afbd27cef15006cd26 325 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 19 307 1.7E-151 T 16-09-2016 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149+1.14.13.14|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176|UniPathway: UPA00930 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 SUPERFAMILY SSF52402 8 145 1.34E-24 T 16-09-2016 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 SUPERFAMILY SSF52402 153 291 6.95E-22 T 16-09-2016 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 Gene3D G3DSA:3.40.50.620 152 290 2.8E-23 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 Gene3D G3DSA:3.40.50.620 3 142 7.9E-28 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 PANTHER PTHR31964 1 161 1.4E-30 T 16-09-2016 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 PRINTS PR01438 Universal stress protein signature 102 114 1.4E-12 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 PRINTS PR01438 Universal stress protein signature 5 23 1.4E-12 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 PRINTS PR01438 Universal stress protein signature 120 142 1.4E-12 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 Pfam PF00582 Universal stress protein family 153 290 1.6E-21 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 Pfam PF00582 Universal stress protein family 8 142 1.3E-24 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS03975 6fd0c7590d734c9a4290fa43ee2f554b 293 PANTHER PTHR31964:SF42 1 161 1.4E-30 T 16-09-2016 Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Gene3D G3DSA:3.40.50.970 346 520 4.0E-44 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Gene3D G3DSA:3.40.50.1220 183 335 5.3E-38 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 SUPERFAMILY SSF52518 350 522 9.65E-46 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 517 1.9E-25 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 PANTHER PTHR18968:SF133 4 521 4.9E-227 T 16-09-2016 Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 SUPERFAMILY SSF52467 184 340 5.29E-52 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 PANTHER PTHR18968 4 521 4.9E-227 T 16-09-2016 Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 SUPERFAMILY SSF52518 9 168 2.31E-35 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Gene3D G3DSA:3.40.50.970 7 169 3.4E-39 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 322 4.8E-18 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS01555 80e88eaf2efffc248b446012c7b83665 526 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 167 2.5E-36 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 PANTHER PTHR30328 7 219 1.5E-106 T 16-09-2016 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.7E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.9E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.9E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 SUPERFAMILY SSF48498 89 201 1.42E-5 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 PANTHER PTHR30328:SF28 7 219 1.5E-106 T 16-09-2016 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 Gene3D G3DSA:1.10.357.10 4 201 1.2E-44 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS18880 eb96545f956470f72909a0fd80ff7a2c 225 SUPERFAMILY SSF46689 6 84 9.75E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31630 12f62181e08c86c82fd192a14c31229d 674 Pfam PF06241 Castor and Pollux, part of voltage-gated ion channel 273 364 3.4E-16 T 16-09-2016 IPR010420 CASTOR/POLLUX/SYM8 ion channels Spa2297_RS31630 12f62181e08c86c82fd192a14c31229d 674 PANTHER PTHR31563 4 635 1.2E-300 T 16-09-2016 Spa2297_RS31630 12f62181e08c86c82fd192a14c31229d 674 PANTHER PTHR31563:SF3 4 635 1.2E-300 T 16-09-2016 Spa2297_RS31630 12f62181e08c86c82fd192a14c31229d 674 Gene3D G3DSA:3.40.50.720 388 515 9.2E-5 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31630 12f62181e08c86c82fd192a14c31229d 674 Gene3D G3DSA:3.40.50.720 121 259 2.6E-14 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04070 46975a6fc24665bab665460012dfc0af 250 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 61 236 6.1E-44 T 16-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like Spa2297_RS04070 46975a6fc24665bab665460012dfc0af 250 PANTHER PTHR30518:SF2 5 247 6.8E-69 T 16-09-2016 Spa2297_RS04070 46975a6fc24665bab665460012dfc0af 250 Gene3D G3DSA:3.30.160.60 208 242 1.2E-6 T 16-09-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 Spa2297_RS04070 46975a6fc24665bab665460012dfc0af 250 PANTHER PTHR30518 5 247 6.8E-69 T 16-09-2016 Spa2297_RS04070 46975a6fc24665bab665460012dfc0af 250 Pfam PF02618 YceG-like family 17 234 3.5E-59 T 16-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Gene3D G3DSA:3.30.300.30 401 500 3.1E-33 T 16-09-2016 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 PANTHER PTHR24096 4 499 2.8E-173 T 16-09-2016 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Gene3D G3DSA:3.40.50.980 163 322 3.6E-43 T 16-09-2016 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Pfam PF00501 AMP-binding enzyme 11 406 4.3E-107 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Gene3D G3DSA:3.40.50.980 6 162 4.0E-41 T 16-09-2016 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 489 6.3E-19 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 SUPERFAMILY SSF56801 5 503 3.4E-161 T 16-09-2016 Spa2297_RS28400 f5c4b7b9f37f160931ab76d425b095c5 506 Gene3D G3DSA:2.30.38.10 323 400 1.4E-25 T 16-09-2016 Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 Gene3D G3DSA:3.40.50.720 1 117 2.7E-66 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 Gene3D G3DSA:3.40.50.720 150 325 2.7E-66 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 262 1.0E-41 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 SUPERFAMILY SSF51735 145 327 4.36E-78 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 SUPERFAMILY SSF51735 1 108 4.36E-78 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 PANTHER PTHR10366:SF367 2 331 4.2E-138 T 16-09-2016 Spa2297_RS17155 102a475149fe9b1f6c773accf1cdf4e1 333 PANTHER PTHR10366 2 331 4.2E-138 T 16-09-2016 Spa2297_RS14635 bca0e28b275378f3e9f7c01fd384b333 1049 PANTHER PTHR32387 19 625 0.0 T 16-09-2016 Spa2297_RS14635 bca0e28b275378f3e9f7c01fd384b333 1049 Gene3D G3DSA:3.30.565.10 31 232 1.7E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14635 bca0e28b275378f3e9f7c01fd384b333 1049 PANTHER PTHR32387:SF5 19 625 0.0 T 16-09-2016 Spa2297_RS14635 bca0e28b275378f3e9f7c01fd384b333 1049 SUPERFAMILY SSF55874 53 139 2.59E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 50 63 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 Pfam PF00741 Gas vesicle protein 16 54 7.4E-12 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 PANTHER PTHR35344:SF3 2 125 2.1E-78 T 16-09-2016 Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 5 91 31.173 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 17 31 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS30425 b9fccd6ecdf38ba002bb24b8ec104a0a 175 PANTHER PTHR35344 2 125 2.1E-78 T 16-09-2016 Spa2297_RS30225 860082a48a42fa00cf7c6c2962a7f072 63 Pfam PF14404 Ribosomally synthesized peptide in Streptomyces species 1 63 7.2E-37 T 16-09-2016 IPR025744 Ribosomally synthesised peptide in Streptomyces Spa2297_RS30225 860082a48a42fa00cf7c6c2962a7f072 63 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 1 63 2.2E-13 T 16-09-2016 IPR026496 Putative ATP-grasp target RiPP Spa2297_RS29580 135bf933dfb1266443cc4d20507e0eba 462 SUPERFAMILY SSF53300 290 406 4.08E-6 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS29580 135bf933dfb1266443cc4d20507e0eba 462 Pfam PF05762 VWA domain containing CoxE-like protein 233 453 4.3E-48 T 16-09-2016 IPR008912 Uncharacterised protein family CoxE-like Spa2297_RS29580 135bf933dfb1266443cc4d20507e0eba 462 PANTHER PTHR39338 4 462 6.9E-112 T 16-09-2016 Spa2297_RS29580 135bf933dfb1266443cc4d20507e0eba 462 PIRSF PIRSF010256 1 462 8.4E-123 T 16-09-2016 IPR011195 Uncharacterised conserved protein UCP010256 Spa2297_RS29580 135bf933dfb1266443cc4d20507e0eba 462 PANTHER PTHR39338:SF2 4 462 6.9E-112 T 16-09-2016 Spa2297_RS31075 aa1882eb6f14902ecc56364ae96b5a15 361 PANTHER PTHR30472:SF24 1 361 4.6E-164 T 16-09-2016 Spa2297_RS31075 aa1882eb6f14902ecc56364ae96b5a15 361 Gene3D G3DSA:1.10.3470.10 37 361 8.1E-87 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS31075 aa1882eb6f14902ecc56364ae96b5a15 361 PANTHER PTHR30472 1 361 4.6E-164 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31075 aa1882eb6f14902ecc56364ae96b5a15 361 Pfam PF01032 FecCD transport family 47 357 2.2E-81 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31075 aa1882eb6f14902ecc56364ae96b5a15 361 SUPERFAMILY SSF81345 30 357 2.88E-67 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 1.2E-76 T 16-09-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 SUPERFAMILY SSF52374 3 324 2.87E-98 T 16-09-2016 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 419 44.164 T 16-09-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PANTHER PTHR11766:SF0 3 419 5.7E-193 T 16-09-2016 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 Gene3D G3DSA:1.10.240.10 234 317 7.9E-39 T 16-09-2016 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 Gene3D G3DSA:3.40.50.620 2 233 1.3E-94 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PANTHER PTHR11766 3 419 5.7E-193 T 16-09-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 SUPERFAMILY SSF55174 327 417 9.03E-16 T 16-09-2016 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 1.5E-26 T 16-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 1.5E-26 T 16-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 1.5E-26 T 16-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 1.5E-26 T 16-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 Gene3D G3DSA:3.10.290.10 318 419 6.4E-32 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS07235 a86ea8b7d2507a27c29e607556389dd9 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 2.3E-112 T 16-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 SUPERFAMILY SSF52540 54 256 5.74E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 PANTHER PTHR24220 45 257 2.4E-90 T 16-09-2016 Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 PANTHER PTHR24220:SF117 45 257 2.4E-90 T 16-09-2016 Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 SMART SM00382 68 251 3.3E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 Gene3D G3DSA:3.40.50.300 54 256 4.5E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS28150 5008f0a692de7a40bd0427618073d08d 262 Pfam PF00005 ABC transporter 60 193 2.1E-16 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 SUPERFAMILY SSF55073 195 342 2.59E-29 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 Pfam PF00990 Diguanylate cyclase, GGDEF domain 190 342 7.7E-27 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 Gene3D G3DSA:3.30.450.40 14 185 1.0E-12 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 SMART SM00267 179 349 7.7E-44 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 SUPERFAMILY SSF55781 25 181 4.42E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 342 2.7E-25 T 16-09-2016 IPR000160 GGDEF domain Spa2297_RS20875 22ca34ef366184d47f3d8574a41536e2 382 Gene3D G3DSA:3.30.70.270 191 343 5.8E-34 T 16-09-2016 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 1.1E-50 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 Gene3D G3DSA:3.30.930.10 7 361 9.9E-143 T 16-09-2016 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 Gene3D G3DSA:3.40.50.800 362 456 1.0E-39 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 SUPERFAMILY SSF52954 353 457 6.04E-34 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.577 T 16-09-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 229 5.1E-81 T 16-09-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 PANTHER PTHR10745 7 457 3.9E-211 T 16-09-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 Pfam PF03129 Anticodon binding domain 366 454 2.4E-23 T 16-09-2016 IPR004154 Anticodon-binding Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 SUPERFAMILY SSF55681 5 369 1.99E-120 T 16-09-2016 Spa2297_RS10560 6e670ff3acf0a7b4f983143705f3db77 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 8.8E-9 T 16-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 PANTHER PTHR18866:SF74 149 265 5.6E-25 T 16-09-2016 Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 PANTHER PTHR18866 149 265 5.6E-25 T 16-09-2016 Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 Gene3D G3DSA:2.40.100.10 176 287 4.5E-11 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 6 286 4.4E-79 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 Pfam PF02626 Allophanate hydrolase subunit 2 28 284 5.1E-85 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 SUPERFAMILY SSF50891 176 287 7.21E-16 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05270 bb7f47cf7f71332a35fdf00fd6f658dd 289 SMART SM00797 27 289 3.9E-100 T 16-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B Spa2297_RS13835 557b73f42cc9486d08cbb813cd1e77e2 202 SUPERFAMILY SSF55729 2 177 1.7E-40 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13835 557b73f42cc9486d08cbb813cd1e77e2 202 PANTHER PTHR13256:SF24 6 200 9.2E-39 T 16-09-2016 Spa2297_RS13835 557b73f42cc9486d08cbb813cd1e77e2 202 Pfam PF13302 Acetyltransferase (GNAT) domain 6 153 3.1E-17 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS13835 557b73f42cc9486d08cbb813cd1e77e2 202 Gene3D G3DSA:3.40.630.30 1 183 6.6E-57 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13835 557b73f42cc9486d08cbb813cd1e77e2 202 PANTHER PTHR13256 6 200 9.2E-39 T 16-09-2016 Spa2297_RS10235 89a414955495c96db01f6c97af6b4061 518 SUPERFAMILY SSF53850 235 505 5.29E-44 T 16-09-2016 Spa2297_RS10235 89a414955495c96db01f6c97af6b4061 518 Gene3D G3DSA:3.40.190.10 324 463 2.9E-30 T 16-09-2016 Spa2297_RS10235 89a414955495c96db01f6c97af6b4061 518 Pfam PF12849 PBP superfamily domain 229 489 6.0E-27 T 16-09-2016 IPR024370 PBP domain Spa2297_RS10235 89a414955495c96db01f6c97af6b4061 518 PANTHER PTHR30570:SF1 139 514 3.2E-135 T 16-09-2016 Spa2297_RS10235 89a414955495c96db01f6c97af6b4061 518 PANTHER PTHR30570 139 514 3.2E-135 T 16-09-2016 Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 SMART SM00382 33 224 7.1E-19 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 Pfam PF00005 ABC transporter 24 163 3.7E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 SUPERFAMILY SSF52540 16 228 4.28E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 Gene3D G3DSA:3.40.50.300 7 219 3.8E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19280 e91b55a3cb2ab5abb35277a54c9216e4 247 PANTHER PTHR24220 10 214 2.2E-74 T 16-09-2016 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 Gene3D G3DSA:3.40.309.10 248 432 3.8E-68 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 PANTHER PTHR11699:SF28 2 458 2.3E-270 T 16-09-2016 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 SUPERFAMILY SSF53720 3 460 3.4E-149 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 Pfam PF00171 Aldehyde dehydrogenase family 3 457 1.6E-145 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 Gene3D G3DSA:3.40.605.10 3 247 3.5E-76 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04350 2604f898643e5ac29c68d3907e5289b2 461 PANTHER PTHR11699 2 458 2.3E-270 T 16-09-2016 Spa2297_RS21525 5426fecc01917a594de2a0c154b02cb2 355 SUPERFAMILY SSF51445 112 296 6.77E-13 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS21525 5426fecc01917a594de2a0c154b02cb2 355 Gene3D G3DSA:3.20.20.80 155 299 4.2E-12 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS21525 5426fecc01917a594de2a0c154b02cb2 355 Pfam PF00704 Glycosyl hydrolases family 18 155 299 2.7E-7 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 SMART SM00354 7 77 1.3E-22 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 Gene3D G3DSA:1.10.260.40 7 57 6.8E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 Gene3D G3DSA:3.40.50.2300 58 185 2.9E-29 T 16-09-2016 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 Gene3D G3DSA:3.40.50.2300 186 317 9.3E-49 T 16-09-2016 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 PANTHER PTHR30146 7 349 5.7E-136 T 16-09-2016 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 PANTHER PTHR30146:SF48 7 349 5.7E-136 T 16-09-2016 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 SUPERFAMILY SSF53822 80 349 9.6E-60 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 Pfam PF13377 Periplasmic binding protein-like domain 181 331 2.9E-32 T 16-09-2016 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 9.3E-17 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS27940 410049fcec477f8fd74f314aa1ac761d 350 SUPERFAMILY SSF47413 7 64 9.7E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03465 389c66d0b6bb4acd7655cd4a16c12be5 132 PANTHER PTHR35908 1 132 9.6E-42 T 16-09-2016 Spa2297_RS03465 389c66d0b6bb4acd7655cd4a16c12be5 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 3.4E-8 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS03465 389c66d0b6bb4acd7655cd4a16c12be5 132 Gene3D G3DSA:3.10.180.10 2 118 3.3E-16 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03465 389c66d0b6bb4acd7655cd4a16c12be5 132 SUPERFAMILY SSF54593 2 118 6.05E-20 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03465 389c66d0b6bb4acd7655cd4a16c12be5 132 PANTHER PTHR35908:SF1 1 132 9.6E-42 T 16-09-2016 Spa2297_RS19540 59d07cdbbbab8edaab9b4986e915a2e8 218 SUPERFAMILY SSF51735 1 204 8.31E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19540 59d07cdbbbab8edaab9b4986e915a2e8 218 Pfam PF13460 NAD(P)H-binding 7 192 7.4E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS19540 59d07cdbbbab8edaab9b4986e915a2e8 218 PANTHER PTHR15020 1 216 1.0E-38 T 16-09-2016 Spa2297_RS19540 59d07cdbbbab8edaab9b4986e915a2e8 218 Gene3D G3DSA:3.40.50.720 1 205 2.6E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 PANTHER PTHR11751:SF410 21 440 2.9E-102 T 16-09-2016 Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 Gene3D G3DSA:3.90.1150.10 277 438 1.2E-35 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 Pfam PF00155 Aminotransferase class I and II 113 433 5.5E-29 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 SUPERFAMILY SSF53383 36 439 7.84E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 Gene3D G3DSA:3.40.640.10 86 276 6.4E-42 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02905 7f6afd7e35df4e0b67387192a2a59804 457 PANTHER PTHR11751 21 440 2.9E-102 T 16-09-2016 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 Gene3D G3DSA:3.40.50.1950 3 177 7.2E-62 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 Pfam PF02441 Flavoprotein 5 130 3.9E-32 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 PANTHER PTHR14359:SF20 1 399 9.5E-178 T 16-09-2016 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 369 6.8E-71 T 16-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 SUPERFAMILY SSF52507 2 176 3.01E-59 T 16-09-2016 IPR003382 Flavoprotein GO:0003824 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 Gene3D G3DSA:3.40.50.10300 182 399 1.2E-81 T 16-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 395 7.6E-122 T 16-09-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|UniPathway: UPA00241|UniPathway: UPA00241 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 SUPERFAMILY SSF102645 175 399 6.02E-69 T 16-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 Spa2297_RS05555 fd2f9a288d40bdda63920446b00fc607 400 PANTHER PTHR14359 1 399 9.5E-178 T 16-09-2016 Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 SUPERFAMILY SSF103501 1 221 1.83E-67 T 16-09-2016 IPR023234 NarG-like domain Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 Gene3D G3DSA:1.20.950.20 1 213 3.8E-74 T 16-09-2016 Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 221 1.3E-57 T 16-09-2016 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 PANTHER PTHR30598:SF3 1 240 5.0E-134 T 16-09-2016 Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 PANTHER PTHR30598 1 240 5.0E-134 T 16-09-2016 Spa2297_RS27215 8dd2d33260df94d24a4ff30e1336e531 240 Pfam PF02665 Nitrate reductase gamma subunit 2 221 3.0E-84 T 16-09-2016 IPR023234 NarG-like domain Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 PANTHER PTHR39515:SF2 1 144 6.4E-70 T 16-09-2016 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 4.5E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.5E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.5E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 PANTHER PTHR39515 1 144 6.4E-70 T 16-09-2016 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 SUPERFAMILY SSF46785 13 137 8.06E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 Gene3D G3DSA:1.10.10.10 9 136 3.0E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 Pfam PF12802 MarR family 36 93 5.1E-14 T 16-09-2016 Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS14610 89d4a574b1eb183072cd8db0f9d356d5 145 SMART SM00347 29 129 1.2E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 PIRSF PIRSF028846 5 431 6.1E-170 T 16-09-2016 IPR008313 Meiotically up-regulated gene 157 protein Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 SUPERFAMILY SSF48208 18 429 1.64E-154 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 Gene3D G3DSA:1.50.10.10 18 427 1.7E-147 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 SMART SM01149 25 420 2.3E-239 T 16-09-2016 IPR008313 Meiotically up-regulated gene 157 protein Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 Pfam PF06824 Protein of unknown function (DUF1237) 25 418 9.4E-133 T 16-09-2016 IPR008313 Meiotically up-regulated gene 157 protein Spa2297_RS00365 ec681cff402a96749530840cf7c3b1e8 435 PANTHER PTHR31047 11 431 9.1E-185 T 16-09-2016 Spa2297_RS00585 5baf5d119f14d8deac289a75c4c398bb 223 Pfam PF02570 Precorrin-8X methylmutase 26 220 5.6E-73 T 16-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 Spa2297_RS00585 5baf5d119f14d8deac289a75c4c398bb 223 SUPERFAMILY SSF63965 17 220 7.85E-73 T 16-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 Spa2297_RS00585 5baf5d119f14d8deac289a75c4c398bb 223 Gene3D G3DSA:3.40.50.10230 15 219 4.7E-81 T 16-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 Spa2297_RS00585 5baf5d119f14d8deac289a75c4c398bb 223 PANTHER PTHR32439 19 218 7.9E-73 T 16-09-2016 Spa2297_RS14310 a657bc2db17786b4a516ee02b83a3c40 505 SMART SM00481 187 251 6.0E-4 T 16-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 Spa2297_RS14310 a657bc2db17786b4a516ee02b83a3c40 505 SUPERFAMILY SSF89550 184 395 4.19E-34 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS14310 a657bc2db17786b4a516ee02b83a3c40 505 Gene3D G3DSA:3.20.20.140 184 365 1.3E-14 T 16-09-2016 Spa2297_RS01420 a792da2943316525454f7b006933f420 133 Gene3D G3DSA:3.30.450.30 3 123 5.8E-23 T 16-09-2016 Spa2297_RS01420 a792da2943316525454f7b006933f420 133 SUPERFAMILY SSF103196 3 126 1.36E-24 T 16-09-2016 Spa2297_RS01420 a792da2943316525454f7b006933f420 133 Pfam PF03259 Roadblock/LC7 domain 7 96 3.2E-22 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS01420 a792da2943316525454f7b006933f420 133 PANTHER PTHR36222 2 130 1.8E-47 T 16-09-2016 Spa2297_RS01420 a792da2943316525454f7b006933f420 133 SMART SM00960 6 97 6.5E-22 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 PANTHER PTHR33406:SF5 4 726 5.3E-228 T 16-09-2016 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 SUPERFAMILY SSF82866 459 696 1.96E-25 T 16-09-2016 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 PANTHER PTHR33406 4 726 5.3E-228 T 16-09-2016 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 SUPERFAMILY SSF82866 114 331 3.66E-31 T 16-09-2016 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 Pfam PF03176 MMPL family 42 367 1.6E-67 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 Pfam PF03176 MMPL family 452 700 4.3E-32 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 Gene3D G3DSA:1.20.1640.10 480 700 9.7E-29 T 16-09-2016 Spa2297_RS23280 c1c409039a02a2eea77900ee815776e6 748 Gene3D G3DSA:1.20.1640.10 137 338 3.6E-30 T 16-09-2016 Spa2297_RS11775 cada158e4132370db7b09d26bcc5f73b 348 Pfam PF01497 Periplasmic binding protein 87 318 1.2E-14 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS11775 cada158e4132370db7b09d26bcc5f73b 348 Gene3D G3DSA:3.40.50.1980 52 183 3.0E-10 T 16-09-2016 Spa2297_RS11775 cada158e4132370db7b09d26bcc5f73b 348 SUPERFAMILY SSF53807 53 328 8.24E-31 T 16-09-2016 Spa2297_RS11775 cada158e4132370db7b09d26bcc5f73b 348 Gene3D G3DSA:3.40.50.1980 184 341 4.0E-13 T 16-09-2016 Spa2297_RS11775 cada158e4132370db7b09d26bcc5f73b 348 PANTHER PTHR30532 8 322 1.4E-22 T 16-09-2016 Spa2297_RS25615 b1544b754565667cb2714914d098eb41 196 Pfam PF13180 PDZ domain 112 181 1.5E-12 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS25615 b1544b754565667cb2714914d098eb41 196 Gene3D G3DSA:2.30.42.10 112 193 1.5E-14 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS25615 b1544b754565667cb2714914d098eb41 196 SUPERFAMILY SSF50156 121 187 8.23E-12 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS25615 b1544b754565667cb2714914d098eb41 196 SMART SM00228 111 182 1.1E-5 T 16-09-2016 IPR001478 PDZ domain GO:0005515 Spa2297_RS08290 e5755c934a169352160f53681e2f89dc 257 PANTHER PTHR13887 11 255 3.6E-44 T 16-09-2016 Spa2297_RS08290 e5755c934a169352160f53681e2f89dc 257 PANTHER PTHR13887:SF14 11 255 3.6E-44 T 16-09-2016 Spa2297_RS08290 e5755c934a169352160f53681e2f89dc 257 Pfam PF13462 Thioredoxin 84 254 3.9E-26 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS08290 e5755c934a169352160f53681e2f89dc 257 Gene3D G3DSA:3.40.30.10 87 253 4.9E-33 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS08290 e5755c934a169352160f53681e2f89dc 257 SUPERFAMILY SSF52833 82 254 1.03E-27 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 Gene3D G3DSA:3.30.1330.40 3 119 6.1E-43 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 2.4E-49 T 16-09-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 118 2.0E-52 T 16-09-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 PIRSF PIRSF005965 1 120 5.9E-41 T 16-09-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 PANTHER PTHR21164:SF0 1 120 1.3E-49 T 16-09-2016 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 Pfam PF07736 Chorismate mutase type I 3 118 6.7E-40 T 16-09-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 PANTHER PTHR21164 1 120 1.3E-49 T 16-09-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 Spa2297_RS06945 8d1601edac27362aba693b3125ae8581 120 SUPERFAMILY SSF55298 2 118 6.44E-39 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 Gene3D G3DSA:3.10.290.10 19 61 6.1E-9 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 SUPERFAMILY SSF55174 19 107 1.57E-7 T 16-09-2016 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 PANTHER PTHR11079 2 312 1.4E-103 T 16-09-2016 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 Pfam PF00849 RNA pseudouridylate synthase 93 247 4.5E-31 T 16-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 307 8.9E-86 T 16-09-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 Pfam PF01479 S4 domain 19 62 5.4E-6 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 SUPERFAMILY SSF55120 82 309 5.28E-68 T 16-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS08470 21d1d817589a046da16496aee157f76e 314 PANTHER PTHR11079:SF73 2 312 1.4E-103 T 16-09-2016 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SMART SM00028 619 652 140.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SMART SM00028 577 610 14.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SMART SM00028 494 527 40.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Gene3D G3DSA:1.25.40.10 493 705 2.1E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Gene3D G3DSA:3.40.50.300 257 281 3.2E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Gene3D G3DSA:3.40.50.300 133 157 3.2E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SUPERFAMILY SSF48452 492 608 2.21E-11 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 PANTHER PTHR19959:SF170 492 676 6.6E-22 T 16-09-2016 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Pfam PF00931 NB-ARC domain 131 320 1.6E-5 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 PANTHER PTHR19959 492 676 6.6E-22 T 16-09-2016 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SUPERFAMILY SSF48452 577 704 6.83E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Gene3D G3DSA:3.40.50.300 158 200 2.7E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 SUPERFAMILY SSF52540 117 360 5.0E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03340 60ef5811ed9bfa4b67cf939b524e9a76 727 Pfam PF13424 Tetratricopeptide repeat 582 651 5.7E-11 T 16-09-2016 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 PANTHER PTHR13593:SF49 433 492 6.6E-103 T 16-09-2016 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 PANTHER PTHR13593:SF49 522 735 6.6E-103 T 16-09-2016 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 PANTHER PTHR13593 433 492 6.6E-103 T 16-09-2016 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 PANTHER PTHR13593 522 735 6.6E-103 T 16-09-2016 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 SUPERFAMILY SSF51695 526 719 6.8E-32 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 SUPERFAMILY SSF51695 435 493 6.8E-32 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 Gene3D G3DSA:3.20.20.190 526 720 1.4E-13 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS03170 321778db1bc013a7b4f34b62b5e710ba 754 Gene3D G3DSA:3.20.20.190 444 489 1.4E-13 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS32855 1f017219f69e7b79721f7d3b7975511e 303 Pfam PF14378 PAP2 superfamily 114 298 3.7E-20 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS32855 1f017219f69e7b79721f7d3b7975511e 303 PANTHER PTHR31310 1 303 2.5E-70 T 16-09-2016 Spa2297_RS32855 1f017219f69e7b79721f7d3b7975511e 303 PANTHER PTHR31310:SF7 1 303 2.5E-70 T 16-09-2016 Spa2297_RS18145 0b8f75c40129dddacb8be06122ad71d9 291 Pfam PF09335 SNARE associated Golgi protein 39 167 1.6E-24 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS18145 0b8f75c40129dddacb8be06122ad71d9 291 PANTHER PTHR30353:SF0 9 291 1.5E-153 T 16-09-2016 Spa2297_RS18145 0b8f75c40129dddacb8be06122ad71d9 291 PANTHER PTHR30353 9 291 1.5E-153 T 16-09-2016 IPR032818 DedA family Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 SMART SM00382 41 224 1.6E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 PANTHER PTHR24220:SF0 304 314 8.2E-91 T 16-09-2016 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 PANTHER PTHR24220:SF0 18 239 8.2E-91 T 16-09-2016 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 Pfam PF00005 ABC transporter 32 175 2.0E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 SUPERFAMILY SSF52540 16 235 5.65E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 Gene3D G3DSA:3.40.50.300 14 236 5.9E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 PANTHER PTHR24220 304 314 8.2E-91 T 16-09-2016 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 PANTHER PTHR24220 18 239 8.2E-91 T 16-09-2016 Spa2297_RS14185 5923686eb00f1be506f7d53267d4b8a4 332 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 24 316 7.2E-95 T 16-09-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- Spa2297_RS12375 d2428e4e3817f1da1523243bf2d00d53 266 PANTHER PTHR36832:SF2 1 266 3.4E-155 T 16-09-2016 Spa2297_RS12375 d2428e4e3817f1da1523243bf2d00d53 266 Pfam PF06182 ABC-2 family transporter protein 43 262 2.8E-16 T 16-09-2016 IPR010390 Protein of unknown function DUF990 Spa2297_RS12375 d2428e4e3817f1da1523243bf2d00d53 266 PANTHER PTHR36832 1 266 3.4E-155 T 16-09-2016 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 275 500 2.0E-36 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 115 512 31.824 T 16-09-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Pfam PF04539 Sigma-70 region 3 358 434 1.1E-28 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 472 498 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PANTHER PTHR30603:SF0 163 512 1.1E-208 T 16-09-2016 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Gene3D G3DSA:1.10.10.10 441 512 2.0E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 303 316 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Pfam PF04542 Sigma-70 region 2 279 348 3.0E-22 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Gene3D G3DSA:1.10.601.10 124 348 5.4E-70 T 16-09-2016 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 SUPERFAMILY SSF88946 211 349 7.72E-54 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PRINTS PR00046 Major sigma-70 factor signature 303 316 6.8E-29 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PRINTS PR00046 Major sigma-70 factor signature 327 335 6.8E-29 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PRINTS PR00046 Major sigma-70 factor signature 472 487 6.8E-29 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PRINTS PR00046 Major sigma-70 factor signature 451 463 6.8E-29 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PRINTS PR00046 Major sigma-70 factor signature 487 498 6.8E-29 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 SUPERFAMILY SSF88659 410 511 2.62E-27 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Gene3D G3DSA:1.10.10.10 352 403 3.8E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Pfam PF00140 Sigma-70 factor, region 1.2 214 247 8.0E-17 T 16-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 SUPERFAMILY SSF88659 352 425 3.92E-21 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 PANTHER PTHR30603 163 512 1.1E-208 T 16-09-2016 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 Pfam PF04545 Sigma-70, region 4 447 500 2.9E-18 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS24655 45664db8f7c5e276674e54dff0d8a4d7 512 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 275 511 9.0E-113 T 16-09-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS12465 df1ec0856984b49f542e1b6b8cadb132 475 PANTHER PTHR11785:SF29 5 474 1.1E-277 T 16-09-2016 Spa2297_RS12465 df1ec0856984b49f542e1b6b8cadb132 475 Pfam PF00324 Amino acid permease 25 437 9.4E-108 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS12465 df1ec0856984b49f542e1b6b8cadb132 475 PANTHER PTHR11785 5 474 1.1E-277 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS12465 df1ec0856984b49f542e1b6b8cadb132 475 PIRSF PIRSF006060 4 472 1.6E-66 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS12465 df1ec0856984b49f542e1b6b8cadb132 475 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 16-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 Spa2297_RS00045 0722a86d134f3888e2c9ff18e996ca3f 295 Pfam PF13845 Septum formation 31 150 1.5E-12 T 16-09-2016 IPR026004 Septum formation-related domain Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 PANTHER PTHR22935:SF67 38 263 3.1E-111 T 16-09-2016 Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 Gene3D G3DSA:3.30.1380.10 37 260 8.5E-71 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 SUPERFAMILY SSF55166 37 260 1.26E-60 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 PIRSF PIRSF026671 10 265 2.2E-73 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 PANTHER PTHR22935 38 263 3.1E-111 T 16-09-2016 Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 39 259 30.929 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 Pfam PF01427 D-ala-D-ala dipeptidase 39 162 4.3E-18 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS05150 f364a4a6b8aae6c053f879c87e01865a 269 Pfam PF01427 D-ala-D-ala dipeptidase 193 260 4.5E-14 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 PANTHER PTHR30346:SF6 1 285 4.4E-103 T 16-09-2016 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 Gene3D G3DSA:3.40.190.10 150 240 2.4E-17 T 16-09-2016 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 3 13 3.5E-5 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 3.5E-5 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 Gene3D G3DSA:1.10.10.10 1 59 3.3E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 SUPERFAMILY SSF53850 61 270 1.15E-25 T 16-09-2016 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 PANTHER PTHR30346 1 285 4.4E-103 T 16-09-2016 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 Pfam PF03466 LysR substrate binding domain 61 267 1.9E-29 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 SUPERFAMILY SSF46785 1 61 1.63E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 Gene3D G3DSA:3.40.190.10 62 149 5.4E-16 T 16-09-2016 Spa2297_RS17080 15c320df5a709ca1bb328a461daeb2af 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 35 3.3E-11 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 5.6E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.6E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 71 4.6E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 Gene3D G3DSA:1.10.357.10 17 181 7.1E-23 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 PANTHER PTHR30055 9 195 6.4E-51 T 16-09-2016 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 PANTHER PTHR30055:SF19 9 195 6.4E-51 T 16-09-2016 Spa2297_RS29230 930e91a04ff35762a285eb1757839eed 197 SUPERFAMILY SSF46689 17 87 4.51E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 PANTHER PTHR30489:SF0 152 163 1.3E-99 T 16-09-2016 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 Pfam PF02687 FtsX-like permease family 244 361 7.6E-16 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 Pfam PF02687 FtsX-like permease family 693 809 1.7E-9 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 PANTHER PTHR30489 214 818 1.3E-99 T 16-09-2016 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 PANTHER PTHR30489 152 163 1.3E-99 T 16-09-2016 Spa2297_RS19685 d86855a947bdaba300db3de708c183cb 819 PANTHER PTHR30489:SF0 214 818 1.3E-99 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238 111 158 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238 2 86 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238 244 366 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238:SF3 244 366 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238:SF3 2 86 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238:SF3 176 193 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238:SF3 111 158 3.4E-170 T 16-09-2016 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 Pfam PF04332 Protein of unknown function (DUF475) 44 361 2.0E-139 T 16-09-2016 IPR007427 Protein of unknown function DUF475 Spa2297_RS30775 84a6feb66476b6c947ac7a7d79744c91 366 PANTHER PTHR30238 176 193 3.4E-170 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PANTHER PTHR11533 22 644 6.5E-188 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 SUPERFAMILY SSF55486 206 456 2.34E-76 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 Gene3D G3DSA:1.10.390.10 308 457 2.5E-43 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PANTHER PTHR11533:SF190 22 644 6.5E-188 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 295 310 1.0E-22 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 314 326 1.0E-22 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 178 193 1.0E-22 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 1.0E-22 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 1.0E-22 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 Pfam PF01433 Peptidase family M1 37 389 9.0E-74 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 Pfam PF11838 ERAP1-like C-terminal domain 535 844 1.0E-58 T 16-09-2016 IPR024571 ERAP1-like C-terminal domain Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PANTHER PTHR11533 667 704 6.5E-188 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 PANTHER PTHR11533:SF190 667 704 6.5E-188 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 SUPERFAMILY SSF63737 5 195 1.44E-39 T 16-09-2016 Spa2297_RS11195 f435cf36816ae4fcb1670e67fc4320de 858 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 850 0.0 T 16-09-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 275 8.1E-36 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Gene3D G3DSA:1.10.10.10 213 277 5.7E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Gene3D G3DSA:1.10.601.10 27 113 4.9E-17 T 16-09-2016 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 SUPERFAMILY SSF88659 123 202 1.48E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PRINTS PR00046 Major sigma-70 factor signature 77 90 5.7E-12 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PRINTS PR00046 Major sigma-70 factor signature 260 271 5.7E-12 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PRINTS PR00046 Major sigma-70 factor signature 228 240 5.7E-12 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PRINTS PR00046 Major sigma-70 factor signature 245 260 5.7E-12 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 SUPERFAMILY SSF88946 21 122 5.18E-26 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Pfam PF04545 Sigma-70, region 4 224 273 1.2E-18 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PANTHER PTHR30385:SF7 26 276 1.7E-84 T 16-09-2016 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Pfam PF04542 Sigma-70 region 2 50 122 1.9E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 50 275 5.8E-88 T 16-09-2016 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 SUPERFAMILY SSF88659 189 276 2.06E-24 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PIRSF PIRSF000770 26 278 2.0E-74 T 16-09-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Gene3D G3DSA:1.10.10.10 122 167 2.5E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 Pfam PF04539 Sigma-70 region 3 130 210 8.0E-7 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 PANTHER PTHR30385 26 276 1.7E-84 T 16-09-2016 Spa2297_RS23805 2a52bf329a7466f46df443775bd81117 280 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 245 271 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS13240 6a32e371ad8718ae1f0eb2435ad01231 133 PANTHER PTHR35908:SF2 6 133 3.8E-66 T 16-09-2016 Spa2297_RS13240 6a32e371ad8718ae1f0eb2435ad01231 133 Gene3D G3DSA:3.10.180.10 9 128 6.7E-15 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS13240 6a32e371ad8718ae1f0eb2435ad01231 133 SUPERFAMILY SSF54593 6 128 1.03E-17 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS13240 6a32e371ad8718ae1f0eb2435ad01231 133 PANTHER PTHR35908 6 133 3.8E-66 T 16-09-2016 Spa2297_RS20055 0c7c279ac486bdecd60442f9a5d751e2 118 PANTHER PTHR35174:SF1 3 117 3.5E-40 T 16-09-2016 Spa2297_RS20055 0c7c279ac486bdecd60442f9a5d751e2 118 PANTHER PTHR35174 3 117 3.5E-40 T 16-09-2016 Spa2297_RS20055 0c7c279ac486bdecd60442f9a5d751e2 118 SUPERFAMILY SSF54909 4 117 2.28E-26 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS20055 0c7c279ac486bdecd60442f9a5d751e2 118 Gene3D G3DSA:3.30.70.1060 2 117 5.7E-33 T 16-09-2016 Spa2297_RS20055 0c7c279ac486bdecd60442f9a5d751e2 118 Pfam PF03795 YCII-related domain 7 97 1.4E-11 T 16-09-2016 IPR005545 YCII-related Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 PANTHER PTHR13774 3 126 8.6E-27 T 16-09-2016 Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 Gene3D G3DSA:3.10.310.10 129 208 3.3E-7 T 16-09-2016 Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 Pfam PF02567 Phenazine biosynthesis-like protein 16 82 1.9E-9 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 PANTHER PTHR13774:SF15 3 126 8.6E-27 T 16-09-2016 Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 Gene3D G3DSA:3.10.310.10 3 118 3.6E-17 T 16-09-2016 Spa2297_RS09475 4f630cd7abe06f68e7c8bf30920d03bb 214 SUPERFAMILY SSF54506 3 212 4.19E-28 T 16-09-2016 Spa2297_RS31660 7a25ed136a3f0225c6c922c045af7197 148 PANTHER PTHR26402 8 133 1.3E-31 T 16-09-2016 Spa2297_RS31660 7a25ed136a3f0225c6c922c045af7197 148 SMART SM00448 8 130 1.2E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS31660 7a25ed136a3f0225c6c922c045af7197 148 Gene3D G3DSA:3.40.50.2300 5 133 3.0E-36 T 16-09-2016 Spa2297_RS31660 7a25ed136a3f0225c6c922c045af7197 148 SUPERFAMILY SSF52172 7 134 3.27E-33 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS31660 7a25ed136a3f0225c6c922c045af7197 148 Pfam PF00072 Response regulator receiver domain 10 130 6.0E-21 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS27535 e5f4c58b483b3b1013351320f853559a 342 SUPERFAMILY SSF161098 86 317 6.28E-54 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27535 e5f4c58b483b3b1013351320f853559a 342 PANTHER PTHR30193:SF25 12 335 7.5E-191 T 16-09-2016 Spa2297_RS27535 e5f4c58b483b3b1013351320f853559a 342 PANTHER PTHR30193 12 335 7.5E-191 T 16-09-2016 Spa2297_RS27535 e5f4c58b483b3b1013351320f853559a 342 Gene3D G3DSA:1.10.3720.10 34 319 4.6E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27535 e5f4c58b483b3b1013351320f853559a 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 326 3.6E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 PANTHER PTHR26402 2 202 8.6E-97 T 16-09-2016 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 PANTHER PTHR26402:SF563 2 202 8.6E-97 T 16-09-2016 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 16-09-2016 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 144 201 7.9E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS20110 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 12 124 6.0E-30 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 Gene3D G3DSA:3.30.360.10 149 333 1.3E-69 T 16-09-2016 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 PANTHER PTHR10174:SF2 64 354 2.2E-59 T 16-09-2016 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 147 337 7.8E-43 T 16-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 PIRSF PIRSF000148 9 355 4.5E-112 T 16-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 9 351 32.402 T 16-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 PANTHER PTHR10174 64 354 2.2E-59 T 16-09-2016 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 SMART SM00859 11 126 7.4E-39 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 SUPERFAMILY SSF51735 12 163 6.15E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 12 351 7.6E-113 T 16-09-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 SUPERFAMILY SSF55347 135 338 5.36E-64 T 16-09-2016 Spa2297_RS17750 e1a08a11db3022ba4b1976d133e2ce88 355 Gene3D G3DSA:3.40.50.720 11 148 1.4E-55 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 9.3E-35 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.2E-35 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.2E-35 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.2E-35 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 1.0E-18 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.796 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 Pfam PF01016 Ribosomal L27 protein 2 80 1.4E-35 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 Gene3D G3DSA:2.40.50.100 20 82 2.7E-28 T 16-09-2016 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 16-09-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 PANTHER PTHR15893 1 84 7.3E-44 T 16-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10960 afbf3967303058d5b5e8b8cfcadbf01e 84 SUPERFAMILY SSF110324 2 81 1.36E-30 T 16-09-2016 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 SMART SM00729 11 213 1.3E-9 T 16-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 329 1.6E-110 T 16-09-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 16-09-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 2 329 40.706 T 16-09-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 Pfam PF13353 4Fe-4S single cluster domain 18 102 7.0E-7 T 16-09-2016 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 Gene3D G3DSA:3.20.20.70 2 306 4.3E-80 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 PANTHER PTHR22960 1 283 1.9E-121 T 16-09-2016 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 Pfam PF04055 Radical SAM superfamily 16 177 2.8E-32 T 16-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 309 2.1E-37 T 16-09-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS07255 0d6d4bcecb91fa33c82b5c76ab9a4175 329 SUPERFAMILY SSF102114 3 277 4.71E-73 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031 541 660 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 SUPERFAMILY SSF52540 107 391 6.36E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 Pfam PF00271 Helicase conserved C-terminal domain 272 370 1.5E-22 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031:SF334 34 450 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031:SF334 676 711 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 SMART SM00487 55 255 6.2E-49 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 Gene3D G3DSA:3.40.50.300 245 394 1.9E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 Gene3D G3DSA:3.40.50.300 27 244 3.0E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 SMART SM00490 289 370 7.9E-29 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031:SF334 541 660 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031 34 450 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 PANTHER PTHR24031 676 711 0.0 T 16-09-2016 Spa2297_RS15690 a52f2db1e984e13759eb9d5511e36cac 721 Pfam PF00270 DEAD/DEAH box helicase 60 228 1.3E-44 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Pfam PF07691 PA14 domain 430 546 8.0E-7 T 16-09-2016 IPR011658 PA14 domain Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 SUPERFAMILY SSF52279 555 709 2.09E-46 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 SUPERFAMILY SSF52279 324 396 2.09E-46 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PANTHER PTHR30620 538 816 1.5E-231 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PANTHER PTHR30620 13 390 1.5E-231 T 16-09-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 SMART SM01217 735 805 3.5E-17 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PRINTS PR00133 Glycosyl hydrolase family 3 signature 74 93 9.6E-31 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PRINTS PR00133 Glycosyl hydrolase family 3 signature 151 167 9.6E-31 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PRINTS PR00133 Glycosyl hydrolase family 3 signature 221 239 9.6E-31 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PRINTS PR00133 Glycosyl hydrolase family 3 signature 45 61 9.6E-31 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PRINTS PR00133 Glycosyl hydrolase family 3 signature 120 136 9.6E-31 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Gene3D G3DSA:3.40.50.1700 555 708 3.1E-63 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Gene3D G3DSA:3.40.50.1700 314 395 3.1E-63 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 SUPERFAMILY SSF56988 446 600 1.57E-6 T 16-09-2016 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 46 289 5.4E-50 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 325 706 2.9E-50 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Gene3D G3DSA:3.20.20.300 13 300 2.3E-90 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PANTHER PTHR30620:SF18 538 816 1.5E-231 T 16-09-2016 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 PANTHER PTHR30620:SF18 13 390 1.5E-231 T 16-09-2016 Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 SUPERFAMILY SSF51445 9 322 1.68E-84 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS10070 01f04d0f4271d55f67d7469fd3a2f4ff 816 Pfam PF14310 Fibronectin type III-like domain 735 804 3.7E-17 T 16-09-2016 IPR026891 Fibronectin type III-like domain Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 PANTHER PTHR30346:SF2 1 302 1.2E-124 T 16-09-2016 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 Gene3D G3DSA:1.10.10.10 1 88 1.5E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 SUPERFAMILY SSF53850 89 299 4.16E-35 T 16-09-2016 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.4E-20 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 PANTHER PTHR30346 1 302 1.2E-124 T 16-09-2016 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 Gene3D G3DSA:3.40.190.10 182 267 1.7E-21 T 16-09-2016 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 Pfam PF03466 LysR substrate binding domain 88 296 6.5E-40 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 Gene3D G3DSA:3.40.190.10 91 181 2.7E-17 T 16-09-2016 Spa2297_RS04965 a9d4a3d8003cc07fccd5e2e67239c30d 303 SUPERFAMILY SSF46785 1 112 4.66E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01145 0bc89975618925a0b839bdb681909620 164 Gene3D G3DSA:1.20.120.450 2 163 4.3E-42 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS01145 0bc89975618925a0b839bdb681909620 164 SUPERFAMILY SSF109854 2 159 1.07E-35 T 16-09-2016 Spa2297_RS01145 0bc89975618925a0b839bdb681909620 164 Pfam PF04978 Protein of unknown function (DUF664) 19 160 3.3E-40 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS04870 df34fa2de17ef1884b188bdd3cb1e84e 157 PANTHER PTHR33204 1 149 3.1E-71 T 16-09-2016 Spa2297_RS04870 df34fa2de17ef1884b188bdd3cb1e84e 157 Pfam PF01638 HxlR-like helix-turn-helix 19 106 2.4E-19 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS04870 df34fa2de17ef1884b188bdd3cb1e84e 157 PANTHER PTHR33204:SF10 1 149 3.1E-71 T 16-09-2016 Spa2297_RS04870 df34fa2de17ef1884b188bdd3cb1e84e 157 SUPERFAMILY SSF46785 8 143 5.33E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04870 df34fa2de17ef1884b188bdd3cb1e84e 157 Gene3D G3DSA:1.10.10.10 7 107 2.1E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 PANTHER PTHR33744 115 655 8.0E-23 T 16-09-2016 Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 Pfam PF13556 PucR C-terminal helix-turn-helix domain 588 646 3.2E-19 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 SUPERFAMILY SSF55781 89 272 1.11E-28 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 Pfam PF13185 GAF domain 105 248 9.4E-16 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 Gene3D G3DSA:3.30.450.40 83 260 6.2E-34 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03355 5f81770d6ae083c16eea3324a5936eac 655 SMART SM00065 106 257 2.8E-21 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 SUPERFAMILY SSF56801 349 611 1.27E-106 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 SUPERFAMILY SSF56801 18 295 1.27E-106 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Gene3D G3DSA:3.40.50.980 22 192 1.2E-25 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Pfam PF00501 AMP-binding enzyme 24 478 3.0E-84 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Gene3D G3DSA:3.40.50.980 346 408 4.1E-23 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Gene3D G3DSA:3.40.50.980 193 290 4.1E-23 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Gene3D G3DSA:3.30.300.30 476 597 2.7E-6 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 PANTHER PTHR24096:SF193 10 613 3.0E-194 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 Gene3D G3DSA:2.30.38.10 409 469 4.7E-18 T 16-09-2016 Spa2297_RS02025 ab6f1357012a3d57df8e760a6bd3b74d 636 PANTHER PTHR24096 10 613 3.0E-194 T 16-09-2016 Spa2297_RS08330 0ec9199a1379801940a443ce25fffe8c 139 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 16 119 31.358 T 16-09-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 Spa2297_RS08330 0ec9199a1379801940a443ce25fffe8c 139 PANTHER PTHR21256 11 118 5.2E-61 T 16-09-2016 Spa2297_RS08330 0ec9199a1379801940a443ce25fffe8c 139 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 42 114 1.4E-32 T 16-09-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 Spa2297_RS08330 0ec9199a1379801940a443ce25fffe8c 139 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 65 114 2.0E-23 T 16-09-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 Spa2297_RS08330 0ec9199a1379801940a443ce25fffe8c 139 SUPERFAMILY SSF141734 18 119 2.22E-46 T 16-09-2016 Spa2297_RS12400 6de171c517538b402f4011231e185954 155 Pfam PF00578 AhpC/TSA family 8 134 3.7E-37 T 16-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS12400 6de171c517538b402f4011231e185954 155 PANTHER PTHR10681 1 153 6.0E-47 T 16-09-2016 Spa2297_RS12400 6de171c517538b402f4011231e185954 155 Gene3D G3DSA:3.40.30.10 2 153 2.9E-49 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS12400 6de171c517538b402f4011231e185954 155 SUPERFAMILY SSF52833 4 153 1.25E-46 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 Pfam PF08281 Sigma-70, region 4 121 173 1.5E-14 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 Gene3D G3DSA:1.10.1740.10 1 108 6.3E-30 T 16-09-2016 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 Gene3D G3DSA:1.10.10.10 115 173 2.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 Pfam PF04542 Sigma-70 region 2 21 88 2.6E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 SUPERFAMILY SSF88659 115 174 1.29E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 SUPERFAMILY SSF88946 1 106 1.02E-27 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 PANTHER PTHR30173:SF24 1 231 4.3E-95 T 16-09-2016 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 174 3.4E-29 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS16515 81738a127d7491742551a54a938d8d62 232 PANTHER PTHR30173 1 231 4.3E-95 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 442 1.7E-108 T 16-09-2016 IPR010071 Amino acid adenylation domain Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Gene3D G3DSA:3.30.300.30 412 514 3.0E-26 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Gene3D G3DSA:2.30.38.10 331 407 1.3E-21 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 SUPERFAMILY SSF56801 8 514 1.15E-137 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Pfam PF00501 AMP-binding enzyme 14 417 1.7E-87 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 PANTHER PTHR24095 11 502 4.8E-135 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Gene3D G3DSA:3.40.50.980 168 330 1.5E-39 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Gene3D G3DSA:3.40.50.980 8 167 2.7E-40 T 16-09-2016 Spa2297_RS02855 36bcc1a4640d1d5a6b9e41c0045daf06 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 502 8.0E-11 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 Pfam PF07702 UTRA domain 109 249 7.9E-29 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 PANTHER PTHR11751 12 104 5.8E-36 T 16-09-2016 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 PANTHER PTHR11751:SF3 12 104 5.8E-36 T 16-09-2016 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 Gene3D G3DSA:1.10.10.10 9 77 2.7E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 SMART SM00866 108 250 9.5E-26 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 Gene3D G3DSA:3.40.1410.10 78 253 1.2E-53 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.2E-17 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 SMART SM00345 17 76 3.8E-19 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 9.9E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 9.9E-5 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 SUPERFAMILY SSF64288 64 255 4.32E-35 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS17395 196131be7b29e3983918a9f76442b5ec 259 SUPERFAMILY SSF46785 9 85 2.04E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS08260 93a0442125bf59ccfc3c7dfd7628d692 411 SUPERFAMILY SSF101478 42 404 1.57E-34 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS08260 93a0442125bf59ccfc3c7dfd7628d692 411 Pfam PF03747 ADP-ribosylglycohydrolase 50 375 1.9E-30 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS30945 c17050eb7491a127d07d2cff5f4321ac 287 SUPERFAMILY SSF161098 13 287 1.03E-69 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30945 c17050eb7491a127d07d2cff5f4321ac 287 PANTHER PTHR32243 8 287 5.7E-159 T 16-09-2016 Spa2297_RS30945 c17050eb7491a127d07d2cff5f4321ac 287 Gene3D G3DSA:1.10.3720.10 10 274 1.6E-66 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30945 c17050eb7491a127d07d2cff5f4321ac 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 278 3.2E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30945 c17050eb7491a127d07d2cff5f4321ac 287 PANTHER PTHR32243:SF42 8 287 5.7E-159 T 16-09-2016 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 PANTHER PTHR10245 2 187 1.7E-62 T 16-09-2016 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 SUPERFAMILY SSF47413 7 74 1.31E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 Gene3D G3DSA:2.60.120.10 111 188 4.8E-27 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 Pfam PF07883 Cupin domain 114 182 1.1E-17 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 PANTHER PTHR10245:SF9 2 187 1.7E-62 T 16-09-2016 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 SMART SM00530 14 69 4.0E-14 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 Gene3D G3DSA:1.10.260.40 11 110 3.7E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 SUPERFAMILY SSF51182 62 184 1.13E-24 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS04815 d9ffe69e7c5bb58f5f94832409d930b3 190 Pfam PF01381 Helix-turn-helix 15 68 1.5E-12 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 SUPERFAMILY SSF51735 5 165 9.36E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 PANTHER PTHR22981 1 296 4.8E-123 T 16-09-2016 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 Gene3D G3DSA:1.10.1040.10 168 293 9.9E-42 T 16-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 SUPERFAMILY SSF48179 166 293 5.78E-38 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 PANTHER PTHR22981:SF70 1 296 4.8E-123 T 16-09-2016 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 287 4.3E-40 T 16-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 296 1.1E-152 T 16-09-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 PIRSF PIRSF000103 1 295 2.5E-82 T 16-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 165 4.2E-50 T 16-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 Spa2297_RS26300 a894ac3507c3b55a93e6c9701851c850 296 Gene3D G3DSA:3.40.50.720 5 166 4.1E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01695 8732e636c8e748c3bd70bf961d3625e2 317 PANTHER PTHR30472:SF24 1 315 1.3E-100 T 16-09-2016 Spa2297_RS01695 8732e636c8e748c3bd70bf961d3625e2 317 SUPERFAMILY SSF81345 3 309 2.48E-71 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01695 8732e636c8e748c3bd70bf961d3625e2 317 PANTHER PTHR30472 1 315 1.3E-100 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01695 8732e636c8e748c3bd70bf961d3625e2 317 Gene3D G3DSA:1.10.3470.10 2 311 1.2E-89 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01695 8732e636c8e748c3bd70bf961d3625e2 317 Pfam PF01032 FecCD transport family 4 309 8.2E-83 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.931 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 3.4E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 3.4E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 3.4E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 3.4E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 3.4E-17 T 16-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 16-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 16-09-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 SUPERFAMILY SSF51419 63 328 8.29E-78 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 2.1E-25 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 2.1E-25 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 2.1E-25 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 2.1E-25 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 Gene3D G3DSA:3.20.20.10 72 314 3.7E-92 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 Gene3D G3DSA:2.40.37.10 315 462 3.0E-49 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 317 438 1.7E-15 T 16-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 71 327 1.2E-64 T 16-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 SUPERFAMILY SSF50621 302 462 2.93E-49 T 16-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 43 461 5.4E-146 T 16-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PANTHER PTHR11482 31 460 2.7E-154 T 16-09-2016 Spa2297_RS22595 f00e07a71ace131bda7448c9a8c573c4 463 PANTHER PTHR11482:SF5 31 460 2.7E-154 T 16-09-2016 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 Pfam PF01547 Bacterial extracellular solute-binding protein 57 346 8.7E-27 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 Gene3D G3DSA:3.40.190.10 57 172 2.9E-8 T 16-09-2016 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 PANTHER PTHR30061 1 369 5.6E-113 T 16-09-2016 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 SUPERFAMILY SSF53850 27 419 3.78E-39 T 16-09-2016 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 Gene3D G3DSA:3.40.190.10 173 365 1.5E-18 T 16-09-2016 Spa2297_RS31220 55fb146f7620fdc1376e79d1920f1433 429 PANTHER PTHR30061:SF20 1 369 5.6E-113 T 16-09-2016 Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 320 2.2E-29 T 16-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 PANTHER PTHR18968 1 575 0.0 T 16-09-2016 Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Gene3D G3DSA:3.40.50.1220 186 342 1.2E-39 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 SUPERFAMILY SSF52518 360 545 2.16E-58 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 SUPERFAMILY SSF52518 4 176 9.49E-43 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Gene3D G3DSA:3.40.50.970 355 552 3.1E-57 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.1E-43 T 16-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 SUPERFAMILY SSF52467 183 346 2.14E-41 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Gene3D G3DSA:3.40.50.970 2 180 6.7E-52 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 PANTHER PTHR18968:SF12 1 575 0.0 T 16-09-2016 Spa2297_RS26090 35dcea22f73121f9cea1d9453841434b 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 1.1E-39 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 8.6E-27 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 8.6E-27 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 8.6E-27 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 8.6E-27 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PANTHER PTHR13789 10 368 7.1E-106 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 PANTHER PTHR13789:SF210 10 368 7.1E-106 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 Gene3D G3DSA:3.30.9.10 170 314 3.6E-51 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 SUPERFAMILY SSF51905 14 187 8.65E-50 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 SUPERFAMILY SSF51905 289 403 8.65E-50 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 Gene3D G3DSA:3.50.50.60 5 169 9.7E-15 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 SUPERFAMILY SSF54373 193 290 2.0E-31 T 16-09-2016 Spa2297_RS04795 c635705ecbf9909280e192e9cd663bbb 407 Pfam PF01494 FAD binding domain 16 357 2.8E-61 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 Gene3D G3DSA:3.30.450.40 296 447 7.5E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SUPERFAMILY SSF81606 490 681 7.85E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SMART SM00331 475 684 2.3E-38 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SUPERFAMILY SSF55785 172 255 4.89E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 PANTHER PTHR21021 450 682 1.0E-50 T 16-09-2016 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SUPERFAMILY SSF55781 310 454 9.38E-15 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 Pfam PF08448 PAS fold 176 259 2.0E-6 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 502 682 4.2E-47 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 Gene3D G3DSA:3.30.450.20 171 263 2.6E-11 T 16-09-2016 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SMART SM00065 308 454 0.0046 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 Pfam PF13185 GAF domain 309 445 4.0E-11 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 PANTHER PTHR21021:SF19 450 682 1.0E-50 T 16-09-2016 Spa2297_RS01090 9c5b7b8bb183bcd87233d801ccf6c6a5 686 SMART SM00091 170 236 1.3E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 Gene3D G3DSA:3.30.450.40 86 248 3.8E-36 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 SMART SM00346 10 98 2.0E-10 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 SUPERFAMILY SSF46785 10 76 1.27E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 Pfam PF01614 Bacterial transcriptional regulator 127 245 9.0E-20 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 SUPERFAMILY SSF55781 82 248 1.63E-28 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 Gene3D G3DSA:1.10.10.10 4 70 2.0E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 Pfam PF09339 IclR helix-turn-helix domain 12 61 9.5E-15 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 PANTHER PTHR30136 7 248 1.2E-69 T 16-09-2016 Spa2297_RS00220 98717d9b700ee07fc1eb09d17f331507 252 PANTHER PTHR30136:SF3 7 248 1.2E-69 T 16-09-2016 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 SMART SM01387 8 88 9.6E-53 T 16-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.358 T 16-09-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 7 89 7.5E-38 T 16-09-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 16-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 SUPERFAMILY SSF47060 3 89 2.03E-35 T 16-09-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 Pfam PF00312 Ribosomal protein S15 8 88 3.0E-37 T 16-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 PANTHER PTHR23321 2 89 2.1E-42 T 16-09-2016 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 1.0E-37 T 16-09-2016 Spa2297_RS24225 d1d10baa9e0c3d295572de390f6650f2 95 Gene3D G3DSA:1.10.287.10 3 89 6.8E-39 T 16-09-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 Pfam PF07730 Histidine kinase 191 254 1.7E-16 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 PANTHER PTHR24421 1 79 1.4E-55 T 16-09-2016 Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 PANTHER PTHR24421 186 382 1.4E-55 T 16-09-2016 Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 PANTHER PTHR24421:SF26 1 79 1.4E-55 T 16-09-2016 Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 SUPERFAMILY SSF55874 277 382 4.65E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04600 34f0c93f8a873936d105a79247e95fb2 384 PANTHER PTHR24421:SF26 186 382 1.4E-55 T 16-09-2016 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 SUPERFAMILY SSF46689 11 87 2.24E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 PANTHER PTHR30328 9 192 1.5E-45 T 16-09-2016 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 SUPERFAMILY SSF48498 84 168 9.39E-11 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.3E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 PANTHER PTHR30328:SF4 9 192 1.5E-45 T 16-09-2016 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 Gene3D G3DSA:1.10.357.10 11 190 7.6E-34 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.5E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28245 56e8b881fc6d7f33b78ecb5a91f8c673 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.5E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS11315 3992f0ed3e3a4c81ceaa9048b3faad9d 565 SMART SM00240 476 536 2.7E-4 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS11315 3992f0ed3e3a4c81ceaa9048b3faad9d 565 SUPERFAMILY SSF49879 422 560 1.63E-22 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS11315 3992f0ed3e3a4c81ceaa9048b3faad9d 565 PANTHER PTHR23308 496 565 1.6E-12 T 16-09-2016 Spa2297_RS11315 3992f0ed3e3a4c81ceaa9048b3faad9d 565 Pfam PF00498 FHA domain 477 555 2.1E-15 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS11315 3992f0ed3e3a4c81ceaa9048b3faad9d 565 Gene3D G3DSA:2.60.200.20 470 559 4.7E-20 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 PANTHER PTHR30595:SF3 1 320 5.0E-59 T 16-09-2016 Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 Pfam PF08279 HTH domain 8 63 4.6E-17 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 Gene3D G3DSA:1.10.10.10 4 66 3.0E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 PANTHER PTHR30595 1 320 5.0E-59 T 16-09-2016 Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 Pfam PF13280 WYL domain 144 315 8.2E-28 T 16-09-2016 IPR026881 WYL domain Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 16-09-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 PIRSF PIRSF016838 1 321 8.3E-23 T 16-09-2016 IPR028349 Protein PafC Spa2297_RS13930 1333bc65ff4f31f1ff88bafab1fdf9d3 325 SUPERFAMILY SSF46785 7 64 7.72E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11985 af2defbc4e86bdcd010ea0c7f4f249ba 300 Gene3D G3DSA:3.10.180.10 12 126 2.8E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS11985 af2defbc4e86bdcd010ea0c7f4f249ba 300 SUPERFAMILY SSF54593 7 252 3.65E-40 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS11985 af2defbc4e86bdcd010ea0c7f4f249ba 300 Gene3D G3DSA:3.10.180.10 142 284 6.5E-40 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS11985 af2defbc4e86bdcd010ea0c7f4f249ba 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 122 4.6E-8 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS11985 af2defbc4e86bdcd010ea0c7f4f249ba 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 141 250 6.0E-18 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 PANTHER PTHR10795:SF389 31 406 1.4E-138 T 16-09-2016 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Gene3D G3DSA:3.40.50.200 115 388 8.8E-85 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Gene3D G3DSA:2.60.120.260 416 527 5.5E-15 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 16-09-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 SUPERFAMILY SSF54897 55 124 1.13E-10 T 16-09-2016 IPR009020 Proteinase inhibitor, propeptide Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 16-09-2016 IPR022398 Peptidase S8, subtilisin, His-active site Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Gene3D G3DSA:3.30.70.80 48 114 1.0E-15 T 16-09-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 SUPERFAMILY SSF52743 133 403 3.93E-76 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 PANTHER PTHR10795 31 406 1.4E-138 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Pfam PF00082 Subtilase family 157 386 4.7E-42 T 16-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Pfam PF05922 Peptidase inhibitor I9 56 123 3.9E-9 T 16-09-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 SUPERFAMILY SSF49785 423 527 3.66E-22 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 Pfam PF01483 Proprotein convertase P-domain 450 527 1.8E-18 T 16-09-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 349 359 - T 16-09-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 1.2E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 348 364 1.2E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS21485 eb66a8d918b726370ea096801bceddde 527 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 1.2E-19 T 16-09-2016 IPR015500 Peptidase S8, subtilisin-related Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SMART SM00091 141 207 0.027 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SMART SM00091 21 86 1.3E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SUPERFAMILY SSF81606 489 687 3.01E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Pfam PF08448 PAS fold 25 134 1.5E-11 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Pfam PF08448 PAS fold 148 260 2.4E-24 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SMART SM00065 270 459 7.9E-7 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 PANTHER PTHR21021:SF19 362 687 4.3E-62 T 16-09-2016 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SUPERFAMILY SSF55785 24 129 1.02E-20 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SMART SM00331 480 688 1.8E-41 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 263 3.8E-8 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 27 138 7.1E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Gene3D G3DSA:3.30.450.20 135 258 1.6E-22 T 16-09-2016 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SUPERFAMILY SSF55781 352 460 1.57E-18 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 SUPERFAMILY SSF55785 133 256 4.32E-15 T 16-09-2016 IPR000014 PAS domain Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Gene3D G3DSA:3.30.450.20 24 129 6.6E-20 T 16-09-2016 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 507 688 2.2E-48 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Pfam PF01590 GAF domain 338 449 4.1E-14 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Gene3D G3DSA:3.60.40.10 617 687 1.7E-4 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 PANTHER PTHR21021 362 687 4.3E-62 T 16-09-2016 Spa2297_RS03060 4477990e0b52f214deb2baf4898e77f7 692 Gene3D G3DSA:3.30.450.40 276 456 4.7E-36 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 16-09-2016 IPR020070 Ribosomal protein L9, N-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 Gene3D G3DSA:3.10.430.100 61 147 2.1E-30 T 16-09-2016 IPR020069 Ribosomal protein L9, C-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.6E-40 T 16-09-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 SUPERFAMILY SSF55653 59 147 9.94E-25 T 16-09-2016 IPR020069 Ribosomal protein L9, C-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 SUPERFAMILY SSF55658 1 56 1.12E-17 T 16-09-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.648 T 16-09-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 1.8E-28 T 16-09-2016 IPR020069 Ribosomal protein L9, C-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 PANTHER PTHR21368 1 147 7.2E-49 T 16-09-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 Gene3D G3DSA:3.40.5.10 1 51 1.3E-22 T 16-09-2016 IPR020070 Ribosomal protein L9, N-terminal Spa2297_RS16425 c7f7329ed8a6f8140f8d81d60f6508d4 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.0E-21 T 16-09-2016 IPR020070 Ribosomal protein L9, N-terminal Spa2297_RS09785 038aff7825f1b21b58c89afc2c8837bd 166 PANTHER PTHR13947 56 158 2.9E-17 T 16-09-2016 Spa2297_RS09785 038aff7825f1b21b58c89afc2c8837bd 166 SUPERFAMILY SSF55729 9 160 6.18E-22 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09785 038aff7825f1b21b58c89afc2c8837bd 166 Pfam PF00583 Acetyltransferase (GNAT) family 68 142 2.3E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS09785 038aff7825f1b21b58c89afc2c8837bd 166 Gene3D G3DSA:3.40.630.30 10 162 2.6E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02180 c4dad1619d1c57dcaf2ef19e7666116a 410 Pfam PF13224 Domain of unknown function (DUF4032) 231 398 8.0E-66 T 16-09-2016 IPR025111 Domain of unknown function DUF4032 Spa2297_RS02180 c4dad1619d1c57dcaf2ef19e7666116a 410 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 61 192 3.9E-6 T 16-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Spa2297_RS02180 c4dad1619d1c57dcaf2ef19e7666116a 410 SUPERFAMILY SSF56112 31 244 1.59E-8 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS02480 4cce6275b716823504f225071126a590 391 SUPERFAMILY SSF55031 170 274 4.34E-23 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS02480 4cce6275b716823504f225071126a590 391 PANTHER PTHR30575 1 391 9.1E-129 T 16-09-2016 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 Pfam PF01546 Peptidase family M20/M25/M40 82 342 1.1E-8 T 16-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 Gene3D G3DSA:3.30.70.360 170 273 4.5E-25 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS02480 4cce6275b716823504f225071126a590 391 PIRSF PIRSF037226 1 391 3.1E-124 T 16-09-2016 IPR017144 Peptidase M20A, amidohydrolase, predicted Spa2297_RS02480 4cce6275b716823504f225071126a590 391 Pfam PF07687 Peptidase dimerisation domain 169 262 2.2E-11 T 16-09-2016 IPR011650 Peptidase M20, dimerisation domain Spa2297_RS02480 4cce6275b716823504f225071126a590 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 345 2.7E-55 T 16-09-2016 IPR017439 Amidohydrolase GO:0016787 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 Gene3D G3DSA:3.40.630.10 2 169 8.9E-62 T 16-09-2016 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 Gene3D G3DSA:3.40.630.10 279 378 8.9E-62 T 16-09-2016 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 SUPERFAMILY SSF53187 282 374 5.66E-56 T 16-09-2016 Spa2297_RS02480 4cce6275b716823504f225071126a590 391 SUPERFAMILY SSF53187 11 182 5.66E-56 T 16-09-2016 Spa2297_RS24885 9ddced8afc6603806abf3b50b4197cb6 116 PIRSF PIRSF006910 1 113 1.9E-53 T 16-09-2016 IPR016499 Nucleic acid binding protein, Rv2694c, predicted Spa2297_RS24885 9ddced8afc6603806abf3b50b4197cb6 116 Gene3D G3DSA:2.40.50.140 27 110 2.7E-9 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 SMART SM00331 378 588 6.2E-28 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 SMART SM00065 204 354 0.0031 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 401 587 1.6E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 PANTHER PTHR21021 298 591 8.5E-45 T 16-09-2016 Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 Gene3D G3DSA:3.30.450.40 192 352 1.8E-18 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 PANTHER PTHR21021:SF19 298 591 8.5E-45 T 16-09-2016 Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 SUPERFAMILY SSF55781 205 355 7.63E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS25930 a4d995c0d3e65662779b94fba661b70e 592 SUPERFAMILY SSF81606 390 588 2.49E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 SUPERFAMILY SSF51735 180 275 2.72E-17 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.2E-44 T 16-09-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 281 5.8E-17 T 16-09-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 SUPERFAMILY SSF69742 1 158 4.32E-44 T 16-09-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 PANTHER PTHR21089 403 488 2.3E-77 T 16-09-2016 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 Gene3D G3DSA:3.40.50.720 183 275 2.1E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 280 5.8E-77 T 16-09-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 16-09-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 SUPERFAMILY SSF69075 448 549 1.31E-14 T 16-09-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 PANTHER PTHR21089 83 267 2.3E-77 T 16-09-2016 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 450 548 4.0E-20 T 16-09-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 546 25.205 T 16-09-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 PANTHER PTHR21089:SF3 403 488 2.3E-77 T 16-09-2016 Spa2297_RS18585 27c5daf7ee3976d4db947d5e729e3781 570 PANTHER PTHR21089:SF3 83 267 2.3E-77 T 16-09-2016 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Hamap MF_01454 GTPase Obg [obg]. 3 330 43.535 T 16-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 SUPERFAMILY SSF102741 353 430 2.75E-21 T 16-09-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Pfam PF01018 GTP1/OBG 4 157 6.0E-52 T 16-09-2016 IPR006169 GTP1/OBG domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Pfam PF01926 50S ribosome-binding GTPase 161 283 8.0E-23 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 328 1.3E-123 T 16-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 429 9.0E-29 T 16-09-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 16-09-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 SUPERFAMILY SSF52540 161 333 5.43E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PANTHER PTHR11702:SF3 357 410 1.1E-134 T 16-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PANTHER PTHR11702:SF3 4 338 1.1E-134 T 16-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Gene3D G3DSA:2.70.210.12 3 156 1.3E-48 T 16-09-2016 IPR006169 GTP1/OBG domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Pfam PF09269 Domain of unknown function (DUF1967) 356 428 4.9E-25 T 16-09-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.0E-35 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.0E-35 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.0E-35 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.0E-35 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 Gene3D G3DSA:3.40.50.300 160 341 4.0E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 SUPERFAMILY SSF82051 4 157 1.57E-46 T 16-09-2016 IPR006169 GTP1/OBG domain GO:0005525 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PANTHER PTHR11702 357 410 1.1E-134 T 16-09-2016 Spa2297_RS10955 7f389618f2d24498bca08195f2a6c1cb 478 PANTHER PTHR11702 4 338 1.1E-134 T 16-09-2016 Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 PANTHER PTHR15032 1 182 1.1E-63 T 16-09-2016 Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 SUPERFAMILY SSF56281 1 60 1.44E-19 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 SUPERFAMILY SSF56281 87 182 1.44E-19 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 SMART SM00849 7 176 2.0E-4 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 Gene3D G3DSA:3.60.15.10 1 178 1.4E-24 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 Pfam PF13483 Beta-lactamase superfamily domain 2 176 1.3E-21 T 16-09-2016 Spa2297_RS26705 684d6f4f54c3fb899be5922f04d1c193 211 PANTHER PTHR15032:SF14 1 182 1.1E-63 T 16-09-2016 Spa2297_RS07420 3e8bca578dbdb5a82990c1ddc5e0b3ee 318 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 283 315 5.0E-4 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 PANTHER PTHR11941:SF86 1 242 1.4E-87 T 16-09-2016 Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 SUPERFAMILY SSF52096 3 242 4.98E-59 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 242 6.5E-40 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 PANTHER PTHR11941 1 242 1.4E-87 T 16-09-2016 Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 Gene3D G3DSA:3.90.226.10 4 178 1.8E-42 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS14485 83e4a62ec976807097d6d26120bb37e2 244 Gene3D G3DSA:1.10.12.10 188 242 2.7E-13 T 16-09-2016 IPR014748 Crontonase, C-terminal Spa2297_RS05545 008ee62092b2a2f1e041f2772f1795db 716 Hamap MF_00983 Probable primosomal protein N' [priA]. 57 715 21.38 T 16-09-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Spa2297_RS05545 008ee62092b2a2f1e041f2772f1795db 716 Gene3D G3DSA:3.40.50.300 209 317 1.9E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05545 008ee62092b2a2f1e041f2772f1795db 716 SUPERFAMILY SSF52540 224 314 4.03E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05545 008ee62092b2a2f1e041f2772f1795db 716 PANTHER PTHR30580 42 716 1.9E-188 T 16-09-2016 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.9E-72 T 16-09-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 16-09-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 Gene3D G3DSA:3.40.50.450 1 211 1.1E-74 T 16-09-2016 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 SUPERFAMILY SSF53784 1 332 8.11E-122 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 Pfam PF00365 Phosphofructokinase 2 298 7.4E-103 T 16-09-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 1.5E-155 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 43.701 T 16-09-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PANTHER PTHR13697 1 331 2.4E-135 T 16-09-2016 Spa2297_RS08705 b93f94761a4d6f5783538a03ffac8328 342 PIRSF PIRSF000532 1 342 3.7E-127 T 16-09-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS13110 243b93a90fd7ae7554f8fd016368798d 538 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 526 6.0E-134 T 16-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 Spa2297_RS13110 243b93a90fd7ae7554f8fd016368798d 538 PANTHER PTHR30003:SF0 1 538 5.7E-255 T 16-09-2016 Spa2297_RS13110 243b93a90fd7ae7554f8fd016368798d 538 PANTHER PTHR30003 1 538 5.7E-255 T 16-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 Spa2297_RS13110 243b93a90fd7ae7554f8fd016368798d 538 Pfam PF02652 L-lactate permease 15 525 5.2E-136 T 16-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 Pfam PF13411 MerR HTH family regulatory protein 1 68 4.3E-18 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 PANTHER PTHR30204 1 107 9.0E-23 T 16-09-2016 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 SUPERFAMILY SSF46955 1 108 4.03E-25 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 Gene3D G3DSA:1.10.1660.10 1 110 5.3E-30 T 16-09-2016 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.4E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS09595 70402cad00f3237b765a156d7a9ca465 253 SMART SM00422 1 70 3.6E-24 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 22 381 3.9E-137 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 PIRSF PIRSF009283 9 381 1.4E-136 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 SUPERFAMILY SSF54593 14 368 1.88E-91 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 PANTHER PTHR11959 1 381 6.3E-176 T 16-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 Gene3D G3DSA:3.10.180.10 188 381 4.8E-80 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 136 5.2E-5 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 194 335 4.2E-16 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS12530 a95cfed5dad7554df1c4517bdd2e2d07 381 Gene3D G3DSA:3.10.180.10 15 187 2.3E-43 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS24950 627cf6764e0928aeedfe77af8ebbd765 436 SMART SM00530 11 66 2.1E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS24950 627cf6764e0928aeedfe77af8ebbd765 436 Gene3D G3DSA:1.10.260.40 6 53 7.1E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS24950 627cf6764e0928aeedfe77af8ebbd765 436 SUPERFAMILY SSF47413 6 59 2.96E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS24950 627cf6764e0928aeedfe77af8ebbd765 436 Pfam PF13560 Helix-turn-helix domain 8 67 5.0E-11 T 16-09-2016 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 386 398 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 107 119 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 55 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 61 73 9.4E-26 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 Pfam PF01266 FAD dependent oxidoreductase 33 397 3.6E-46 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PANTHER PTHR11985:SF16 9 524 5.6E-299 T 16-09-2016 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 391 401 - T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 420 520 2.9E-13 T 16-09-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 Gene3D G3DSA:3.50.50.60 32 307 3.7E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 SUPERFAMILY SSF51905 32 322 5.99E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30335 c4fc424296e21efc506e1f5e2820873a 529 PANTHER PTHR11985 9 524 5.6E-299 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 PANTHER PTHR24362:SF160 8 368 1.1E-88 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 PANTHER PTHR24362:SF160 425 445 1.1E-88 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Pfam PF00069 Protein kinase domain 18 231 3.5E-46 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SMART SM00740 387 454 2.1E-14 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SMART SM00740 523 589 3.0E-17 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SMART SM00740 590 654 1.7E-14 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SMART SM00740 455 522 2.8E-14 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Gene3D G3DSA:3.30.200.20 10 83 2.0E-24 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SUPERFAMILY SSF54184 593 653 4.32E-6 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 PANTHER PTHR24362 8 368 1.1E-88 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 PANTHER PTHR24362 425 445 1.1E-88 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Gene3D G3DSA:1.10.510.10 84 264 1.9E-46 T 16-09-2016 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SMART SM00220 18 270 6.9E-51 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Pfam PF03793 PASTA domain 392 454 2.1E-12 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Pfam PF03793 PASTA domain 526 589 1.1E-15 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Pfam PF03793 PASTA domain 594 653 2.1E-9 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 Pfam PF03793 PASTA domain 459 522 1.4E-12 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS08660 1ce580e6ef586873e3bfeb8536d38667 654 SUPERFAMILY SSF56112 9 272 3.55E-71 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 46 136 1.8E-14 T 16-09-2016 IPR032093 Phospholipase D, N-terminal Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 Gene3D G3DSA:3.60.21.10 141 525 6.0E-36 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 PANTHER PTHR22953:SF40 225 415 5.0E-168 T 16-09-2016 Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 Pfam PF09423 PhoD-like phosphatase 154 507 8.3E-77 T 16-09-2016 IPR018946 Alkaline phosphatase D-related Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 SUPERFAMILY SSF56300 143 521 1.86E-38 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 PANTHER PTHR22953 6 196 5.0E-168 T 16-09-2016 Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 PANTHER PTHR22953 225 415 5.0E-168 T 16-09-2016 Spa2297_RS04720 15899cb55c7e6d3371a0a2196204b27f 528 PANTHER PTHR22953:SF40 6 196 5.0E-168 T 16-09-2016 Spa2297_RS21590 6f6f53d905f35299c880446de6de24d0 307 PANTHER PTHR30465:SF0 1 306 1.3E-116 T 16-09-2016 Spa2297_RS21590 6f6f53d905f35299c880446de6de24d0 307 Gene3D G3DSA:1.10.3720.10 89 301 3.8E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21590 6f6f53d905f35299c880446de6de24d0 307 SUPERFAMILY SSF161098 90 288 7.06E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21590 6f6f53d905f35299c880446de6de24d0 307 PANTHER PTHR30465 1 306 1.3E-116 T 16-09-2016 Spa2297_RS21590 6f6f53d905f35299c880446de6de24d0 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 2.5E-38 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05020 33e39ac4487c86219ca0901a329fce3b 275 Pfam PF02517 CAAX protease self-immunity 169 256 1.0E-14 T 16-09-2016 IPR003675 CAAX amino terminal protease GO:0016020 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 SUPERFAMILY SSF48498 92 203 2.08E-33 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 PANTHER PTHR30055:SF53 9 203 1.8E-80 T 16-09-2016 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 Gene3D G3DSA:1.10.357.10 85 203 2.8E-44 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 SUPERFAMILY SSF46689 12 91 1.69E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 6.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 6.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 Gene3D G3DSA:1.10.10.60 15 73 3.2E-23 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.2E-18 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS18450 8777e0a2849d0a97db44acf2498b4b1d 203 PANTHER PTHR30055 9 203 1.8E-80 T 16-09-2016 Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 229 1.9E-33 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 Pfam PF02567 Phenazine biosynthesis-like protein 6 265 1.3E-57 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 Gene3D G3DSA:3.10.310.10 2 125 2.7E-40 T 16-09-2016 Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 PIRSF PIRSF016184 1 269 2.7E-48 T 16-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 SUPERFAMILY SSF54506 2 267 1.81E-72 T 16-09-2016 Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 PANTHER PTHR13774 1 268 9.6E-101 T 16-09-2016 Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 PANTHER PTHR13774:SF17 1 268 9.6E-101 T 16-09-2016 Spa2297_RS05015 77a6540ed0adce0c914f89eac9eae197 269 Gene3D G3DSA:3.10.310.10 126 257 1.5E-39 T 16-09-2016 Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 PANTHER PTHR23029 4 195 8.1E-115 T 16-09-2016 Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 PANTHER PTHR23029:SF54 4 195 8.1E-115 T 16-09-2016 Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 SMART SM00855 3 156 2.6E-23 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 195 2.3E-53 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 SUPERFAMILY SSF53254 1 196 4.53E-51 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 Gene3D G3DSA:3.40.50.1240 3 194 1.8E-49 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS26360 b03a87a452a0d1009d349dfc749343c9 199 PIRSF PIRSF000709 2 196 8.2E-11 T 16-09-2016 Spa2297_RS15550 a04e02864ae22e287ae2824f250e2544 177 PANTHER PTHR23091 1 158 2.2E-33 T 16-09-2016 Spa2297_RS15550 a04e02864ae22e287ae2824f250e2544 177 PANTHER PTHR23091:SF276 1 158 2.2E-33 T 16-09-2016 Spa2297_RS15550 a04e02864ae22e287ae2824f250e2544 177 Gene3D G3DSA:3.40.630.30 2 171 4.0E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15550 a04e02864ae22e287ae2824f250e2544 177 SUPERFAMILY SSF55729 2 164 9.09E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS15550 a04e02864ae22e287ae2824f250e2544 177 Pfam PF00583 Acetyltransferase (GNAT) family 93 153 4.5E-12 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 SUPERFAMILY SSF55811 6 147 1.1E-34 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 PANTHER PTHR22769:SF42 15 150 3.4E-36 T 16-09-2016 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 7.3E-7 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 7.3E-7 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 Pfam PF00293 NUDIX domain 20 133 8.5E-18 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 Gene3D G3DSA:3.90.79.10 5 145 5.9E-37 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS07700 366f654bb19160e06f0835fa5ecb241f 156 PANTHER PTHR22769 15 150 3.4E-36 T 16-09-2016 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 SUPERFAMILY SSF52166 1 205 1.7E-72 T 16-09-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.4E-61 T 16-09-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 PANTHER PTHR10746 4 202 1.1E-80 T 16-09-2016 IPR013005 50S ribosomal protein uL4 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 209 33.136 T 16-09-2016 IPR013005 50S ribosomal protein uL4 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 Gene3D G3DSA:3.40.1370.10 59 204 3.9E-51 T 16-09-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19800 1f09f88c21205d9dc8932a69adb6e731 218 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.3E-68 T 16-09-2016 IPR013005 50S ribosomal protein uL4 Spa2297_RS29445 eec90c02f89cc0e9a6e893d53abf90ee 332 Pfam PF00294 pfkB family carbohydrate kinase 14 305 1.4E-47 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS29445 eec90c02f89cc0e9a6e893d53abf90ee 332 Gene3D G3DSA:3.40.1190.20 13 318 6.4E-80 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS29445 eec90c02f89cc0e9a6e893d53abf90ee 332 SUPERFAMILY SSF53613 13 316 1.42E-66 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS29445 eec90c02f89cc0e9a6e893d53abf90ee 332 PANTHER PTHR10584:SF186 1 326 9.6E-121 T 16-09-2016 Spa2297_RS29445 eec90c02f89cc0e9a6e893d53abf90ee 332 PANTHER PTHR10584 1 326 9.6E-121 T 16-09-2016 Spa2297_RS07050 a46dc2975e7d4e099b8378a650af4083 115 SUPERFAMILY SSF55718 8 115 5.89E-16 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS07050 a46dc2975e7d4e099b8378a650af4083 115 Gene3D G3DSA:3.30.1050.10 10 115 9.9E-15 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS02535 f2e6b60314a4c8ce0aeb96455c455296 143 SUPERFAMILY SSF141322 81 140 7.45E-6 T 16-09-2016 Spa2297_RS02535 f2e6b60314a4c8ce0aeb96455c455296 143 Gene3D G3DSA:2.40.50.140 81 141 1.3E-22 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS02535 f2e6b60314a4c8ce0aeb96455c455296 143 PANTHER PTHR33507 1 143 3.6E-38 T 16-09-2016 Spa2297_RS02535 f2e6b60314a4c8ce0aeb96455c455296 143 PANTHER PTHR33507:SF3 1 143 3.6E-38 T 16-09-2016 Spa2297_RS02535 f2e6b60314a4c8ce0aeb96455c455296 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 142 7.5E-25 T 16-09-2016 IPR002810 NfeD-like, C-terminal domain Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 PANTHER PTHR11061:SF30 18 450 6.0E-113 T 16-09-2016 Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 Gene3D G3DSA:3.40.50.150 252 444 1.0E-49 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 428 438 - T 16-09-2016 IPR030391 RNA methyltransferase TrmA, conserved site Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 Pfam PF01938 TRAM domain 16 75 2.6E-14 T 16-09-2016 IPR002792 TRAM domain Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 SUPERFAMILY SSF53335 83 445 1.31E-56 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 PANTHER PTHR11061 18 450 6.0E-113 T 16-09-2016 Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 370 444 3.6E-10 T 16-09-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 Gene3D G3DSA:2.40.50.140 18 93 4.0E-22 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS24910 a171ba5bb10da45e1218336ccbab5976 450 SUPERFAMILY SSF50249 17 65 5.43E-10 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:3.90.55.10 778 826 2.6E-4 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 15 1225 0.0 T 16-09-2016 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 SUPERFAMILY SSF50692 1080 1225 7.46E-43 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615 848 874 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615 992 1226 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:3.40.228.10 494 594 6.0E-83 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:3.40.228.10 231 346 6.0E-83 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:2.40.40.20 1053 1225 7.8E-40 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Pfam PF00384 Molybdopterin oxidoreductase 118 829 4.7E-131 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615:SF35 848 874 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615:SF35 992 1226 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:3.40.50.740 153 222 4.2E-6 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615:SF35 44 420 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615 44 420 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615 695 832 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 PANTHER PTHR11615:SF35 695 832 0.0 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Pfam PF01568 Molydopterin dinucleotide binding domain 1085 1194 7.2E-22 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 773 790 - T 16-09-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:3.40.50.740 595 777 2.1E-55 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 Gene3D G3DSA:2.20.25.90 62 107 1.3E-28 T 16-09-2016 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 76 - T 16-09-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 SMART SM00926 53 115 2.0E-4 T 16-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Spa2297_RS27230 b186e64521fea5632294df3b0dabf178 1231 SUPERFAMILY SSF53706 15 1064 0.0 T 16-09-2016 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 SUPERFAMILY SSF55021 18 98 4.16E-20 T 16-09-2016 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 Pfam PF00551 Formyl transferase 101 278 4.0E-37 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PANTHER PTHR10520 13 290 6.7E-158 T 16-09-2016 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 21 47 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 124 151 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 270 295 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 102 124 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 248 270 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 53 65 8.1E-52 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PANTHER PTHR10520:SF7 13 290 6.7E-158 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 PIRSF PIRSF036480 16 297 7.1E-115 T 16-09-2016 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 16 296 48.418 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 Gene3D G3DSA:3.40.50.170 100 292 7.6E-57 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 20 296 4.1E-104 T 16-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 SUPERFAMILY SSF53328 101 296 3.53E-64 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 Gene3D G3DSA:3.30.70.260 16 96 6.7E-30 T 16-09-2016 Spa2297_RS14410 c2f874f76555b805e15c0b4722409de7 297 Pfam PF13740 ACT domain 20 74 2.2E-5 T 16-09-2016 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 Pfam PF00293 NUDIX domain 39 153 8.3E-20 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 PANTHER PTHR22769 21 167 4.1E-21 T 16-09-2016 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 Gene3D G3DSA:3.90.79.10 34 151 1.4E-26 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 SUPERFAMILY SSF55811 24 151 2.44E-27 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 PRINTS PR00502 NUDIX hydrolase family signature 61 75 1.3E-8 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS01040 50ab1590a4f663dd0deee17b76284866 187 PRINTS PR00502 NUDIX hydrolase family signature 75 90 1.3E-8 T 16-09-2016 IPR020476 NUDIX hydrolase Spa2297_RS28345 3618753d1930792e774a43bf15fc18da 119 Pfam PF04237 YjbR 12 99 5.3E-18 T 16-09-2016 IPR007351 Uncharacterised protein YjbR Spa2297_RS28345 3618753d1930792e774a43bf15fc18da 119 SUPERFAMILY SSF142906 2 118 2.75E-23 T 16-09-2016 Spa2297_RS28965 b7755e4c18f6614522d2388b36c7bbe0 277 Gene3D G3DSA:3.20.20.370 80 269 5.5E-61 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS28965 b7755e4c18f6614522d2388b36c7bbe0 277 SUPERFAMILY SSF88713 81 269 1.72E-61 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS28965 b7755e4c18f6614522d2388b36c7bbe0 277 PANTHER PTHR10587 84 270 6.6E-57 T 16-09-2016 Spa2297_RS28965 b7755e4c18f6614522d2388b36c7bbe0 277 Pfam PF01522 Polysaccharide deacetylase 88 206 1.5E-37 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS11365 a8927aae89953611d65b3e7678533091 141 Gene3D G3DSA:3.30.1330.40 4 138 2.5E-29 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS11365 a8927aae89953611d65b3e7678533091 141 PANTHER PTHR11803 22 137 7.4E-35 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS11365 a8927aae89953611d65b3e7678533091 141 Pfam PF01042 Endoribonuclease L-PSP 15 136 2.8E-18 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS11365 a8927aae89953611d65b3e7678533091 141 SUPERFAMILY SSF55298 13 138 3.14E-23 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS11365 a8927aae89953611d65b3e7678533091 141 PANTHER PTHR11803:SF18 22 137 7.4E-35 T 16-09-2016 Spa2297_RS04090 9c1c4cfe7325805a7ab1deb75da7b89f 249 PANTHER PTHR38589 2 249 8.9E-50 T 16-09-2016 Spa2297_RS04090 9c1c4cfe7325805a7ab1deb75da7b89f 249 PANTHER PTHR38589:SF1 2 249 8.9E-50 T 16-09-2016 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 PIRSF PIRSF006078 5 380 1.3E-117 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 6 376 3.6E-117 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 SUPERFAMILY SSF110738 6 377 3.79E-116 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 Gene3D G3DSA:3.90.1510.10 46 280 2.2E-86 T 16-09-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 PANTHER PTHR21599:SF0 5 376 7.5E-137 T 16-09-2016 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 Pfam PF02595 Glycerate kinase family 7 377 9.9E-129 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS26900 8590c0008b820ea07b75339c92e60043 380 PANTHER PTHR21599 5 376 7.5E-137 T 16-09-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 SUPERFAMILY SSF51419 4 230 1.44E-61 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 232 1.6E-43 T 16-09-2016 IPR011078 Uncharacterised protein family UPF0001 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 16-09-2016 IPR011078 Uncharacterised protein family UPF0001 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 PIRSF PIRSF004848 1 236 1.3E-66 T 16-09-2016 IPR011078 Uncharacterised protein family UPF0001 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 PANTHER PTHR10146 3 233 1.5E-71 T 16-09-2016 IPR011078 Uncharacterised protein family UPF0001 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 Pfam PF01168 Alanine racemase, N-terminal domain 12 233 2.2E-22 T 16-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS08505 d51b3387d42ae95245638c65f22c11e6 236 Gene3D G3DSA:3.20.20.10 2 233 9.1E-79 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Gene3D G3DSA:1.10.3090.10 422 444 1.9E-59 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Gene3D G3DSA:1.10.3090.10 168 354 1.9E-59 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Pfam PF01966 HD domain 270 366 2.0E-14 T 16-09-2016 IPR006674 HD domain Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Gene3D G3DSA:3.30.460.10 27 167 1.9E-44 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 SMART SM00471 266 481 3.2E-4 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 195 256 6.6E-21 T 16-09-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 TIGRFAM TIGR00277 HDIG: HDIG domain 267 341 2.4E-17 T 16-09-2016 IPR006675 HDIG domain Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 PANTHER PTHR13734:SF5 31 477 2.9E-114 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 PANTHER PTHR13734 31 477 2.9E-114 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 SUPERFAMILY SSF81301 25 165 2.94E-37 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 23 477 4.1E-248 T 16-09-2016 IPR014065 tRNA adenylyltransferase Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 SUPERFAMILY SSF81891 166 477 5.76E-70 T 16-09-2016 Spa2297_RS16495 08bac27e7b6705518315cb9868c16f9f 481 Pfam PF01743 Poly A polymerase head domain 46 168 3.7E-32 T 16-09-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 Gene3D G3DSA:3.40.1130.10 24 204 3.7E-24 T 16-09-2016 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 PANTHER PTHR10434:SF4 1 235 2.7E-156 T 16-09-2016 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 SMART SM00563 38 152 6.7E-37 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 PANTHER PTHR10434 1 235 2.7E-156 T 16-09-2016 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 SUPERFAMILY SSF69593 18 205 1.44E-37 T 16-09-2016 Spa2297_RS03615 3b279a05cad1aac526b25452344beb47 242 Pfam PF01553 Acyltransferase 24 149 4.7E-30 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS33415 b3a619fdbb27d3e708dee04c5d2d7263 298 Gene3D G3DSA:3.90.1200.10 119 288 2.0E-15 T 16-09-2016 Spa2297_RS33415 b3a619fdbb27d3e708dee04c5d2d7263 298 Pfam PF03881 Fructosamine kinase 74 298 1.6E-36 T 16-09-2016 IPR016477 Fructosamine/Ketosamine-3-kinase Spa2297_RS33415 b3a619fdbb27d3e708dee04c5d2d7263 298 SUPERFAMILY SSF56112 52 297 9.07E-38 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS33415 b3a619fdbb27d3e708dee04c5d2d7263 298 PANTHER PTHR12149 63 298 8.8E-33 T 16-09-2016 Spa2297_RS06320 880df504460ee1230347772c793bcd00 95 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 72 19.949 T 16-09-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Spa2297_RS06320 880df504460ee1230347772c793bcd00 95 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 3.4E-18 T 16-09-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Spa2297_RS06320 880df504460ee1230347772c793bcd00 95 Pfam PF02416 mttA/Hcf106 family 5 55 6.4E-18 T 16-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Spa2297_RS06320 880df504460ee1230347772c793bcd00 95 PANTHER PTHR33162 1 50 2.8E-15 T 16-09-2016 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 Pfam PF01126 Heme oxygenase 3 205 2.2E-65 T 16-09-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PANTHER PTHR10720 1 211 7.2E-66 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 SUPERFAMILY SSF48613 3 209 3.24E-56 T 16-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 Gene3D G3DSA:1.20.910.10 3 208 7.2E-63 T 16-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PIRSF PIRSF000343 1 215 2.9E-65 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 3 28 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 63 88 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 38 63 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 192 210 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 116 137 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS09465 4723006fbbde46ef7f22568d9e228254 215 PRINTS PR00088 Haem oxygenase signature 160 181 5.2E-30 T 16-09-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 243 6.4E-5 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 SUPERFAMILY SSF55347 137 297 1.0E-14 T 16-09-2016 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 SUPERFAMILY SSF51735 3 157 1.74E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 PANTHER PTHR22604 1 340 1.3E-188 T 16-09-2016 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 Gene3D G3DSA:3.30.360.10 154 264 2.3E-32 T 16-09-2016 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 6.6E-20 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 Gene3D G3DSA:3.40.50.720 5 153 8.1E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 3 340 47.692 T 16-09-2016 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 Spa2297_RS02410 b7aad4a7f13fc0205294ccf05148dd9b 342 PANTHER PTHR22604:SF103 1 340 1.3E-188 T 16-09-2016 Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 Pfam PF01471 Putative peptidoglycan binding domain 206 259 2.9E-16 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 SMART SM00530 21 76 0.001 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 SUPERFAMILY SSF47090 202 260 1.46E-16 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 SUPERFAMILY SSF47413 16 78 2.88E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 Gene3D G3DSA:1.10.260.40 21 70 7.5E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 Gene3D G3DSA:1.10.101.10 198 262 4.2E-20 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS15965 54ab3a020b86b91242d2958c8157fd57 265 Pfam PF13560 Helix-turn-helix domain 21 75 6.4E-10 T 16-09-2016 Spa2297_RS09865 097dc506ea7c19beeaefa6a02c8847de 151 Pfam PF07681 DoxX 15 92 1.4E-9 T 16-09-2016 IPR032808 DoxX family Spa2297_RS09865 097dc506ea7c19beeaefa6a02c8847de 151 PANTHER PTHR33452 4 151 1.6E-65 T 16-09-2016 Spa2297_RS09865 097dc506ea7c19beeaefa6a02c8847de 151 PANTHER PTHR33452:SF4 4 151 1.6E-65 T 16-09-2016 Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 PANTHER PTHR24220 4 225 7.7E-76 T 16-09-2016 Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 Pfam PF00005 ABC transporter 22 171 4.2E-35 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 SMART SM00382 31 219 9.3E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 SUPERFAMILY SSF52540 4 223 5.93E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 Gene3D G3DSA:3.40.50.300 3 221 7.4E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04020 37b3f9ecf9dadb2f46717edee0e22b24 227 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24020 7abea74ad29e13d37b1b47d2852cf37f 310 PANTHER PTHR30193:SF10 5 308 7.6E-128 T 16-09-2016 Spa2297_RS24020 7abea74ad29e13d37b1b47d2852cf37f 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 296 2.6E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24020 7abea74ad29e13d37b1b47d2852cf37f 310 Gene3D G3DSA:1.10.3720.10 21 300 3.8E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24020 7abea74ad29e13d37b1b47d2852cf37f 310 SUPERFAMILY SSF161098 25 303 1.02E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24020 7abea74ad29e13d37b1b47d2852cf37f 310 PANTHER PTHR30193 5 308 7.6E-128 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992 182 325 1.5E-44 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992 10 137 1.5E-44 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 Gene3D G3DSA:3.40.50.1820 52 138 1.3E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 Gene3D G3DSA:3.40.50.1820 351 471 1.3E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 Gene3D G3DSA:3.40.50.1820 183 306 1.3E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992 407 455 1.5E-44 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 SUPERFAMILY SSF53474 86 139 2.42E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 SUPERFAMILY SSF53474 373 471 2.42E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 SUPERFAMILY SSF53474 185 299 2.42E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 Pfam PF08386 TAP-like protein 387 483 1.3E-26 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992:SF107 182 325 1.5E-44 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992:SF107 10 137 1.5E-44 T 16-09-2016 Spa2297_RS31345 b93da36908bcff43a876e13e876a2477 487 PANTHER PTHR10992:SF107 407 455 1.5E-44 T 16-09-2016 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 Pfam PF00902 Sec-independent protein translocase protein (TatC) 20 246 1.1E-60 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PANTHER PTHR30371 6 284 4.0E-91 T 16-09-2016 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 251 4.2E-54 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 8 265 17.123 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 110 128 2.7E-36 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 128 154 2.7E-36 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 2.7E-36 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 178 206 2.7E-36 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS06315 e04101a15ea2969115457ecc6cc6ed49 316 PANTHER PTHR30371:SF0 6 284 4.0E-91 T 16-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Spa2297_RS00050 29d365053713314353260e2a0bc83a5c 133 SUPERFAMILY SSF54593 9 130 1.05E-17 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00050 29d365053713314353260e2a0bc83a5c 133 Gene3D G3DSA:3.10.180.10 13 129 8.1E-14 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00050 29d365053713314353260e2a0bc83a5c 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 124 1.1E-5 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PANTHER PTHR11632 475 554 1.1E-275 T 16-09-2016 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PANTHER PTHR11632 1 402 1.1E-275 T 16-09-2016 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.5E-6 T 16-09-2016 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 7.5E-6 T 16-09-2016 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PIRSF PIRSF036654 1 556 4.6E-304 T 16-09-2016 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.-|UniPathway: UPA00062 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 Gene3D G3DSA:3.50.50.60 490 554 1.7E-67 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 Gene3D G3DSA:3.50.50.60 2 274 1.7E-67 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PANTHER PTHR11632:SF38 475 554 1.1E-275 T 16-09-2016 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 Pfam PF00890 FAD binding domain 4 538 1.1E-112 T 16-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 SUPERFAMILY SSF51905 493 554 1.3E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 SUPERFAMILY SSF51905 2 295 1.3E-35 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02160 e9305c72b0519d9f6b3e931d224c631c 557 PANTHER PTHR11632:SF38 1 402 1.1E-275 T 16-09-2016 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 PANTHER PTHR33516:SF2 49 259 2.7E-93 T 16-09-2016 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 SUPERFAMILY SSF46785 52 118 2.88E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 TIGRFAM TIGR00498 lexA: repressor LexA 51 259 3.3E-75 T 16-09-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 Hamap MF_00015 LexA repressor [lexA]. 52 259 34.333 T 16-09-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 Gene3D G3DSA:2.10.109.10 140 258 8.6E-45 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 Pfam PF01726 LexA DNA binding domain 51 114 1.0E-29 T 16-09-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 PANTHER PTHR33516 49 259 2.7E-93 T 16-09-2016 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 Pfam PF00717 Peptidase S24-like 178 243 1.4E-16 T 16-09-2016 IPR019759 Peptidase S24/S26A/S26B Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 175 185 8.5E-11 T 16-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 186 197 8.5E-11 T 16-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 214 226 8.5E-11 T 16-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 SUPERFAMILY SSF51306 139 257 1.26E-36 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS24570 cbfa7d1f66899d1c4236b5d8e484b87f 259 Gene3D G3DSA:1.10.10.10 52 118 1.8E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 ProSitePatterns PS00761 Signal peptidases I signature 3. 174 187 - T 16-09-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 66 82 6.8E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 169 188 6.8E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 120 132 6.8E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 51 215 8.9E-39 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 PANTHER PTHR12383 48 232 3.4E-54 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 Pfam PF00717 Peptidase S24-like 72 135 2.5E-15 T 16-09-2016 IPR019759 Peptidase S24/S26A/S26B Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 PANTHER PTHR12383:SF14 48 232 3.4E-54 T 16-09-2016 Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 Gene3D G3DSA:2.10.109.10 169 223 7.2E-36 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 Gene3D G3DSA:2.10.109.10 63 130 7.2E-36 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23765 5d65aa10b046291d6869784850dcffff 250 SUPERFAMILY SSF51306 65 221 1.88E-41 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS24325 f170cdefc52e8c754164c4923825e97d 287 PANTHER PTHR34475:SF1 19 287 1.4E-46 T 16-09-2016 Spa2297_RS24325 f170cdefc52e8c754164c4923825e97d 287 Pfam PF13413 Helix-turn-helix domain 36 96 2.8E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS24325 f170cdefc52e8c754164c4923825e97d 287 Pfam PF13464 Domain of unknown function (DUF4115) 213 278 1.2E-13 T 16-09-2016 IPR025194 Domain of unknown function DUF4115 Spa2297_RS24325 f170cdefc52e8c754164c4923825e97d 287 PANTHER PTHR34475 19 287 1.4E-46 T 16-09-2016 Spa2297_RS24325 f170cdefc52e8c754164c4923825e97d 287 Gene3D G3DSA:1.10.260.40 23 101 2.4E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:2.30.30.300 220 254 1.2E-8 T 16-09-2016 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 207 576 6.3E-53 T 16-09-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Pfam PF01921 tRNA synthetases class I (K) 12 404 3.2E-133 T 16-09-2016 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 PANTHER PTHR37940 2 177 1.2E-173 T 16-09-2016 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 PANTHER PTHR37940 210 580 1.2E-173 T 16-09-2016 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 51 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 SUPERFAMILY SSF48163 367 579 3.4E-22 T 16-09-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:3.40.50.620 314 363 6.7E-4 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 SUPERFAMILY SSF52374 26 189 2.82E-47 T 16-09-2016 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 SUPERFAMILY SSF52374 219 361 2.82E-47 T 16-09-2016 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:1.10.10.350 484 578 3.0E-18 T 16-09-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 11 580 31.401 T 16-09-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:3.40.50.620 20 173 1.0E-54 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:3.40.50.620 263 313 1.0E-54 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS18640 39a8cb9abe2d1e64efffe638a97b685c 580 Gene3D G3DSA:3.40.50.620 212 219 1.0E-54 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 Gene3D G3DSA:1.10.3720.10 13 214 8.2E-41 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 214 3.2E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 PANTHER PTHR30614 3 214 2.1E-104 T 16-09-2016 Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 3 214 8.2E-82 T 16-09-2016 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 3.0E-30 T 16-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 SUPERFAMILY SSF161098 13 200 4.58E-37 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12085 a6067ca189d3f91d73552f22dfd3c175 216 PANTHER PTHR30614:SF14 3 214 2.1E-104 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 SUPERFAMILY SSF51055 414 456 1.31E-14 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Gene3D G3DSA:2.40.10.10 210 293 3.1E-28 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Gene3D G3DSA:2.10.10.20 413 457 1.2E-21 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 334 4.2E-43 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 236 250 4.2E-43 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 296 316 4.2E-43 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 360 374 4.2E-43 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 359 4.2E-43 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Pfam PF02983 Alpha-lytic protease prodomain 134 191 4.9E-17 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 PIRSF PIRSF001134 3 398 2.6E-153 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Gene3D G3DSA:2.40.10.10 294 382 3.9E-31 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Pfam PF02839 Carbohydrate binding domain 413 454 3.2E-7 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 SMART SM00495 411 457 3.5E-8 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Gene3D G3DSA:3.30.300.50 133 202 1.1E-16 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 Gene3D G3DSA:3.30.300.50 50 132 5.6E-29 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 SUPERFAMILY SSF54806 54 113 1.65E-5 T 16-09-2016 Spa2297_RS19710 9133bbf630940212dbbf070f0474226d 457 SUPERFAMILY SSF50494 212 391 2.1E-34 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS26530 24b5061e1bc5ea1c2fbc212b3e8a4cb9 394 SUPERFAMILY SSF55874 277 384 6.02E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26530 24b5061e1bc5ea1c2fbc212b3e8a4cb9 394 Pfam PF07730 Histidine kinase 187 251 3.1E-14 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS26530 24b5061e1bc5ea1c2fbc212b3e8a4cb9 394 PANTHER PTHR24421 45 393 1.6E-90 T 16-09-2016 Spa2297_RS26530 24b5061e1bc5ea1c2fbc212b3e8a4cb9 394 PANTHER PTHR24421:SF26 45 393 1.6E-90 T 16-09-2016 Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 Gene3D G3DSA:1.10.3300.10 9 184 1.1E-42 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 PANTHER PTHR35525:SF3 18 187 6.1E-28 T 16-09-2016 Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 PANTHER PTHR35525 18 187 6.1E-28 T 16-09-2016 Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 SUPERFAMILY SSF160904 8 180 1.11E-42 T 16-09-2016 Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 Pfam PF07336 Putative stress-induced transcription regulator 14 135 3.5E-21 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS09370 6231ec1c77e60f385a083a209fb80efc 187 Pfam PF11706 CGNR zinc finger 140 181 1.0E-15 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS26665 214749faf4620ded16546733a537296f 200 Gene3D G3DSA:1.20.120.450 13 53 3.3E-4 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS26665 214749faf4620ded16546733a537296f 200 SUPERFAMILY SSF109854 8 137 5.65E-16 T 16-09-2016 Spa2297_RS26665 214749faf4620ded16546733a537296f 200 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 165 1.2E-22 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS26665 214749faf4620ded16546733a537296f 200 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 9 190 5.5E-41 T 16-09-2016 IPR017520 Conserved hypothetical protein CHP03086 Spa2297_RS26665 214749faf4620ded16546733a537296f 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 131 2.6E-11 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 Gene3D G3DSA:3.40.50.720 2 200 6.6E-51 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 Pfam PF00106 short chain dehydrogenase 3 191 7.2E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PIRSF PIRSF000126 1 257 2.7E-53 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.9E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.9E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.9E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 4.9E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.9E-26 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PANTHER PTHR24322 153 184 1.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PANTHER PTHR24322 7 131 1.3E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 8.2E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 8.2E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.2E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS12250 379c3502c994b60185b81dd929d6a9d9 260 SUPERFAMILY SSF51735 3 221 4.23E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 PANTHER PTHR23150:SF24 1 447 8.0E-126 T 16-09-2016 Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 25 441 1.2E-137 T 16-09-2016 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255|UniPathway: UPA01014 Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 Gene3D G3DSA:1.20.120.450 20 129 2.2E-5 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 Pfam PF12867 DinB superfamily 27 157 4.2E-25 T 16-09-2016 IPR024775 DinB-like domain Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 Gene3D G3DSA:3.90.1580.10 182 444 1.1E-76 T 16-09-2016 IPR005532 Sulfatase-modifying factor enzyme Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 Pfam PF03781 Sulfatase-modifying factor enzyme 1 184 442 2.8E-67 T 16-09-2016 IPR005532 Sulfatase-modifying factor enzyme Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 SUPERFAMILY SSF109854 17 153 1.28E-17 T 16-09-2016 Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 SUPERFAMILY SSF56436 183 444 1.17E-77 T 16-09-2016 IPR016187 C-type lectin fold Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 Hamap MF_02035 Hercynine oxygenase [egtB]. 3 444 51.463 T 16-09-2016 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255|UniPathway: UPA01014 Spa2297_RS29080 04ccc05f9dd163deafad647f7019d186 447 PANTHER PTHR23150 1 447 8.0E-126 T 16-09-2016 Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 Gene3D G3DSA:2.60.120.260 633 718 2.5E-16 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 SUPERFAMILY SSF49785 944 1032 7.8E-8 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 SUPERFAMILY SSF49785 630 715 3.54E-14 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 Pfam PF00754 F5/8 type C domain 639 717 1.2E-14 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 Pfam PF00754 F5/8 type C domain 944 1031 6.0E-8 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS00835 1e5adcf6db254399b724871287483ebf 1045 Gene3D G3DSA:2.60.120.260 943 1033 2.9E-7 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 SMART SM00418 245 320 3.1E-6 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 Gene3D G3DSA:1.10.10.10 232 310 3.5E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 SUPERFAMILY SSF46785 244 316 4.97E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 Pfam PF12840 Helix-turn-helix domain 247 302 9.9E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 247 262 2.9E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 293 308 2.9E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS14210 c03dc1418e2edabbfeea8bbb2408959e 332 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 278 293 2.9E-5 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 SUPERFAMILY SSF53822 68 326 2.54E-61 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 Gene3D G3DSA:3.40.50.2300 61 178 1.8E-40 T 16-09-2016 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 SUPERFAMILY SSF47413 8 66 2.16E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 68 323 1.2E-28 T 16-09-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 PANTHER PTHR30146:SF41 8 343 1.5E-214 T 16-09-2016 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 4.6E-18 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 Gene3D G3DSA:3.40.50.2300 179 312 6.5E-37 T 16-09-2016 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 Gene3D G3DSA:1.10.260.40 9 60 2.1E-23 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 SMART SM00354 8 78 6.2E-30 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS00360 d5b61306052caa6fc8e5fa2f90ed54a1 346 PANTHER PTHR30146 8 343 1.5E-214 T 16-09-2016 Spa2297_RS01375 d5ea78ebfa93746b0429f70f3d230884 97 Pfam PF06243 Phenylacetic acid degradation B 8 93 1.9E-38 T 16-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 Spa2297_RS01375 d5ea78ebfa93746b0429f70f3d230884 97 PIRSF PIRSF030200 1 97 1.2E-44 T 16-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 Spa2297_RS01375 d5ea78ebfa93746b0429f70f3d230884 97 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 8 97 7.4E-49 T 16-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 PANTHER PTHR20852:SF57 5 343 1.5E-180 T 16-09-2016 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 82 9.7E-14 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 SUPERFAMILY SSF54368 6 89 1.09E-12 T 16-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 SUPERFAMILY SSF55931 90 338 5.89E-62 T 16-09-2016 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 219 235 - T 16-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 ProSitePatterns PS00180 Glutamine synthetase signature 1. 41 58 - T 16-09-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 PANTHER PTHR20852 5 343 1.5E-180 T 16-09-2016 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 SMART SM01230 89 333 9.6E-48 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 Pfam PF00120 Glutamine synthetase, catalytic domain 96 237 3.1E-11 T 16-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spa2297_RS09230 05bca09b0df941d98ace8cf70c680904 343 Gene3D G3DSA:3.30.590.10 93 338 6.5E-53 T 16-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 SUPERFAMILY SSF56784 7 256 2.52E-68 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 PANTHER PTHR19288:SF40 1 257 1.4E-162 T 16-09-2016 Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 PANTHER PTHR19288 1 257 1.4E-162 T 16-09-2016 Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 1.6E-45 T 16-09-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 Gene3D G3DSA:3.40.50.10410 88 181 4.5E-33 T 16-09-2016 IPR023215 Nitrophenylphosphatase-like domain Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 Pfam PF13242 HAD-hyrolase-like 182 255 7.3E-22 T 16-09-2016 Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 PIRSF PIRSF000915 4 259 5.1E-53 T 16-09-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 8.0E-26 T 16-09-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 Gene3D G3DSA:3.40.50.1000 182 257 3.0E-41 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12150 75ba647055c7a87ae7c958db62b82fdc 259 Gene3D G3DSA:3.40.50.1000 6 83 3.0E-41 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 SUPERFAMILY SSF53633 4 244 2.49E-70 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 PIRSF PIRSF000726 57 417 8.5E-126 T 16-09-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 Gene3D G3DSA:3.40.1160.10 3 244 9.6E-70 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 PANTHER PTHR21499:SF27 3 420 4.0E-181 T 16-09-2016 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 SUPERFAMILY SSF55021 337 411 1.24E-22 T 16-09-2016 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 Pfam PF00696 Amino acid kinase family 3 231 7.9E-53 T 16-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 16-09-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 Pfam PF01842 ACT domain 271 331 2.1E-9 T 16-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 409 7.2E-123 T 16-09-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 409 7.6E-115 T 16-09-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 Pfam PF13840 ACT domain 344 406 3.7E-13 T 16-09-2016 IPR027795 GATS-like ACT domain Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 Gene3D G3DSA:3.30.70.260 269 331 7.4E-4 T 16-09-2016 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 SUPERFAMILY SSF55021 254 332 1.33E-18 T 16-09-2016 Spa2297_RS17745 c67e91cd372819219bf10bbbb53a0df4 425 PANTHER PTHR21499 3 420 4.0E-181 T 16-09-2016 Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 Gene3D G3DSA:3.40.50.720 1 196 1.4E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 Gene3D G3DSA:3.90.25.10 197 319 9.0E-29 T 16-09-2016 Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 PANTHER PTHR10366 2 316 1.8E-97 T 16-09-2016 Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 PANTHER PTHR10366:SF39 2 316 1.8E-97 T 16-09-2016 Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 321 1.1E-99 T 16-09-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 SUPERFAMILY SSF51735 1 321 1.94E-86 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10935 40f924b2544a289a24aef630c4f47003 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 250 5.5E-53 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS21640 5e7b48d7a173741f54af15631767099c 336 Gene3D G3DSA:3.40.630.30 198 329 9.8E-18 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS21640 5e7b48d7a173741f54af15631767099c 336 PANTHER PTHR20958 249 336 1.0E-17 T 16-09-2016 Spa2297_RS21640 5e7b48d7a173741f54af15631767099c 336 SUPERFAMILY SSF55729 142 325 2.57E-16 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS21640 5e7b48d7a173741f54af15631767099c 336 Pfam PF00583 Acetyltransferase (GNAT) family 261 316 4.1E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 Pfam PF07690 Major Facilitator Superfamily 26 417 3.3E-51 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 368 388 8.5E-7 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 107 8.5E-7 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 8.5E-7 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 8.5E-7 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 SUPERFAMILY SSF103473 474 501 1.23E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 SUPERFAMILY SSF103473 256 427 1.23E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 SUPERFAMILY SSF103473 11 206 1.23E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PANTHER PTHR23501:SF65 1 510 1.1E-245 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 Gene3D G3DSA:1.20.1250.20 24 202 3.2E-28 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 Gene3D G3DSA:1.20.1250.20 475 501 2.2E-18 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 Gene3D G3DSA:1.20.1250.20 279 428 2.2E-18 T 16-09-2016 Spa2297_RS06015 c7fc10a1c2a03010b30a90c442aab7aa 510 PANTHER PTHR23501 1 510 1.1E-245 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PANTHER PTHR19375:SF173 2 629 0.0 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 195 205 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 382 401 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 463 479 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 136 156 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 327 343 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.3E-78 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 PANTHER PTHR19375 2 629 0.0 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 631 36.042 T 16-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 SUPERFAMILY SSF100920 378 534 1.29E-56 T 16-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.30.420.40 312 353 8.4E-35 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.30.420.40 190 222 8.4E-35 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 189 202 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.30.30.30 53 104 9.7E-18 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:1.20.1270.10 527 595 2.0E-16 T 16-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:2.60.34.10 384 526 4.0E-65 T 16-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 16-09-2016 IPR018181 Heat shock protein 70, conserved site Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.90.640.10 223 308 7.7E-29 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Pfam PF00012 Hsp70 protein 4 593 1.2E-241 T 16-09-2016 IPR013126 Heat shock protein 70 family Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.30.420.40 4 52 2.6E-64 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 Gene3D G3DSA:3.30.420.40 117 189 2.6E-64 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 SUPERFAMILY SSF53067 4 182 2.65E-61 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 SUPERFAMILY SSF53067 184 376 4.5E-64 T 16-09-2016 Spa2297_RS14020 e42bea5364a4c268ae270cc1f143b557 631 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 597 4.3E-291 T 16-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 Gene3D G3DSA:3.50.50.60 1 177 9.5E-12 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 Gene3D G3DSA:3.50.50.60 291 329 9.5E-12 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 PANTHER PTHR10617:SF114 1 445 4.0E-84 T 16-09-2016 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 SUPERFAMILY SSF51905 2 174 2.94E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 SUPERFAMILY SSF51905 294 383 2.94E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS09645 8f9444a0b8e48a30964f5715c56e6b4a 448 PANTHER PTHR10617 1 445 4.0E-84 T 16-09-2016 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 Pfam PF00355 Rieske [2Fe-2S] domain 37 119 2.6E-18 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 179 371 2.6E-42 T 16-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PANTHER PTHR21266:SF2 13 373 8.4E-79 T 16-09-2016 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 Gene3D G3DSA:3.90.380.10 145 367 3.1E-20 T 16-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 SUPERFAMILY SSF50022 12 150 3.93E-44 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 6.9E-21 T 16-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 6.9E-21 T 16-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 6.9E-21 T 16-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 6.9E-21 T 16-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 6.9E-21 T 16-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 Gene3D G3DSA:2.102.10.10 37 144 2.6E-34 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 PANTHER PTHR21266 13 373 8.4E-79 T 16-09-2016 Spa2297_RS05225 3dd274018bd92f60402eb0d40fe124e1 373 SUPERFAMILY SSF55961 173 371 1.02E-41 T 16-09-2016 Spa2297_RS05610 f72c167400a2a748db5c1d338737bb26 192 Gene3D G3DSA:3.40.50.2020 15 178 7.4E-50 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS05610 f72c167400a2a748db5c1d338737bb26 192 Pfam PF00156 Phosphoribosyl transferase domain 13 153 4.2E-20 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS05610 f72c167400a2a748db5c1d338737bb26 192 SUPERFAMILY SSF53271 12 178 7.48E-41 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS05610 f72c167400a2a748db5c1d338737bb26 192 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 10 183 36.952 T 16-09-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 Spa2297_RS05610 f72c167400a2a748db5c1d338737bb26 192 PANTHER PTHR11608 7 185 7.5E-91 T 16-09-2016 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 PANTHER PTHR22916 1 386 2.2E-107 T 16-09-2016 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 PANTHER PTHR22916 402 502 2.2E-107 T 16-09-2016 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 SUPERFAMILY SSF53756 505 708 8.58E-12 T 16-09-2016 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 341 709 1.1E-129 T 16-09-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 PANTHER PTHR22916:SF3 1 386 2.2E-107 T 16-09-2016 Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 Gene3D G3DSA:3.90.550.10 6 101 5.9E-6 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 SUPERFAMILY SSF53448 2 215 7.31E-10 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12940 8eb86ab05a59c3f9801950c51ac39376 738 PANTHER PTHR22916:SF3 402 502 2.2E-107 T 16-09-2016 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 PANTHER PTHR22604:SF92 1 333 9.2E-107 T 16-09-2016 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 224 1.7E-8 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 PANTHER PTHR22604 1 333 9.2E-107 T 16-09-2016 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 1.3E-20 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 Gene3D G3DSA:3.30.360.10 131 328 1.1E-49 T 16-09-2016 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 SUPERFAMILY SSF55347 125 286 6.54E-26 T 16-09-2016 Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 SUPERFAMILY SSF51735 2 147 2.09E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28505 7052c8af5c8b878ced4f69c6e56db176 334 Gene3D G3DSA:3.40.50.720 1 130 8.4E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 SUPERFAMILY SSF101874 95 267 4.32E-52 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 PANTHER PTHR34406 41 273 4.4E-65 T 16-09-2016 Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 Pfam PF04264 YceI-like domain 97 264 3.0E-39 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 Gene3D G3DSA:2.40.128.110 96 267 9.8E-57 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 Gene3D G3DSA:2.60.40.1120 3 86 1.1E-6 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 SUPERFAMILY SSF49464 6 74 2.79E-6 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 SMART SM00867 96 265 3.7E-63 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS16005 0456e340c27e7b63a65d79ec0a533644 273 PANTHER PTHR34406:SF1 41 273 4.4E-65 T 16-09-2016 Spa2297_RS23385 08d0d6f86543cc412d104e9373971292 484 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 10 448 7.4E-109 T 16-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS23385 08d0d6f86543cc412d104e9373971292 484 PIRSF PIRSF002744 1 466 1.5E-70 T 16-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 Spa2297_RS23385 08d0d6f86543cc412d104e9373971292 484 PANTHER PTHR31806 1 454 8.9E-219 T 16-09-2016 Spa2297_RS23385 08d0d6f86543cc412d104e9373971292 484 PANTHER PTHR31806:SF2 1 454 8.9E-219 T 16-09-2016 Spa2297_RS00090 b416abe748256ed27fa43eee9912aeb2 376 Pfam PF06081 Aromatic acid exporter family member 1 19 158 1.2E-7 T 16-09-2016 IPR010343 Aromatic acid exporter family member 1 Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 Pfam PF00733 Asparagine synthase 271 664 7.4E-8 T 16-09-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 Gene3D G3DSA:3.60.20.10 79 196 1.3E-9 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 SUPERFAMILY SSF52402 267 405 8.2E-8 T 16-09-2016 Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 SUPERFAMILY SSF52402 216 237 8.2E-8 T 16-09-2016 Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 SUPERFAMILY SSF52402 530 637 8.2E-8 T 16-09-2016 Spa2297_RS15620 0ed4b1470bc325271465e9fd8c1ad023 705 SUPERFAMILY SSF56235 34 202 1.54E-15 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS13300 dd09b9a06d140583428aa8c0fa457d95 209 SUPERFAMILY SSF55874 114 200 4.32E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13300 dd09b9a06d140583428aa8c0fa457d95 209 Gene3D G3DSA:3.30.565.10 114 194 4.1E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13300 dd09b9a06d140583428aa8c0fa457d95 209 Pfam PF13581 Histidine kinase-like ATPase domain 89 186 2.7E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 Pfam PF00128 Alpha amylase, catalytic domain 35 383 3.2E-70 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 PANTHER PTHR10357 5 414 6.0E-156 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 PANTHER PTHR10357:SF11 448 499 6.0E-156 T 16-09-2016 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 PANTHER PTHR10357:SF11 5 414 6.0E-156 T 16-09-2016 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 SUPERFAMILY SSF51445 11 465 2.82E-118 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 Gene3D G3DSA:3.90.400.10 112 184 2.3E-27 T 16-09-2016 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 PANTHER PTHR10357 448 499 6.0E-156 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 SMART SM00642 20 409 1.4E-118 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 Pfam PF11941 Domain of unknown function (DUF3459) 455 532 2.3E-7 T 16-09-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 Gene3D G3DSA:3.20.20.80 185 469 4.8E-98 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS28660 bf8a272f37f442afde0ab613011116f9 534 Gene3D G3DSA:3.20.20.80 9 111 4.8E-98 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 Gene3D G3DSA:3.40.50.720 1 170 2.2E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 249 1.2E-50 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 SUPERFAMILY SSF51735 1 316 1.19E-83 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 319 4.0E-100 T 16-09-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 Gene3D G3DSA:3.90.25.10 171 218 5.9E-38 T 16-09-2016 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 Gene3D G3DSA:3.90.25.10 251 322 5.9E-38 T 16-09-2016 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 PANTHER PTHR10366 2 313 9.4E-98 T 16-09-2016 Spa2297_RS12920 1a718b3327dead34c9c567d59bbb0223 326 PANTHER PTHR10366:SF39 2 313 9.4E-98 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 Pfam PF00072 Response regulator receiver domain 12 125 2.8E-13 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 254 9.4E-23 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 334 352 9.4E-23 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 395 9.4E-23 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 508 530 9.4E-23 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 479 9.4E-23 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 233 544 7.6E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 SUPERFAMILY SSF52172 12 140 7.83E-22 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 Gene3D G3DSA:3.50.50.60 338 550 8.1E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 SUPERFAMILY SSF51905 233 555 9.5E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PANTHER PTHR22912:SF138 219 495 6.4E-170 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PANTHER PTHR22912:SF138 515 557 6.4E-170 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PANTHER PTHR22912 219 495 6.4E-170 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PANTHER PTHR22912 515 557 6.4E-170 T 16-09-2016 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 256 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 373 397 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 427 443 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 298 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 282 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 465 486 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 343 7.0E-32 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 SMART SM00448 10 132 1.9E-11 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 Gene3D G3DSA:3.50.50.60 231 337 3.8E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02195 e7d89fb0d224f4f842745c7b86c5ec75 558 Gene3D G3DSA:3.40.50.2300 12 143 5.9E-23 T 16-09-2016 Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 PANTHER PTHR22925 38 328 6.0E-100 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 SUPERFAMILY SSF75005 41 325 8.51E-74 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 PANTHER PTHR22925:SF42 38 328 6.0E-100 T 16-09-2016 Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 Pfam PF06439 Domain of Unknown Function (DUF1080) 338 497 1.3E-6 T 16-09-2016 IPR010496 Domain of unknown function DUF1080 Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 Gene3D G3DSA:2.115.10.20 36 325 1.1E-85 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS00260 99f01bca4382ff69201982a4d7e3fff7 501 Pfam PF04616 Glycosyl hydrolases family 43 43 325 1.3E-58 T 16-09-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spa2297_RS12220 8c253c887c20db875dfca0c6f267e360 285 PANTHER PTHR11820 1 282 4.0E-163 T 16-09-2016 Spa2297_RS12220 8c253c887c20db875dfca0c6f267e360 285 SUPERFAMILY SSF56529 68 282 6.93E-72 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS12220 8c253c887c20db875dfca0c6f267e360 285 PANTHER PTHR11820:SF71 1 282 4.0E-163 T 16-09-2016 Spa2297_RS12220 8c253c887c20db875dfca0c6f267e360 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 281 2.1E-66 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS12220 8c253c887c20db875dfca0c6f267e360 285 Gene3D G3DSA:3.90.850.10 68 283 1.9E-80 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS01035 f83a6a9107c6265aef9a39dd055bf0a2 356 Gene3D G3DSA:3.40.710.10 3 337 1.1E-74 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS01035 f83a6a9107c6265aef9a39dd055bf0a2 356 SUPERFAMILY SSF56601 3 335 7.45E-77 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS01035 f83a6a9107c6265aef9a39dd055bf0a2 356 Pfam PF00144 Beta-lactamase 5 325 1.0E-59 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS01035 f83a6a9107c6265aef9a39dd055bf0a2 356 PANTHER PTHR22935 34 351 5.7E-69 T 16-09-2016 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 16-09-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 Pfam PF01084 Ribosomal protein S18 20 71 5.4E-24 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PANTHER PTHR13479:SF42 2 78 1.2E-51 T 16-09-2016 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 8.4E-16 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 8.4E-16 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 8.4E-16 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 8.4E-16 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 3.0E-24 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 Gene3D G3DSA:4.10.640.10 11 75 3.0E-32 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 SUPERFAMILY SSF46911 5 75 3.01E-28 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.706 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 PANTHER PTHR13479 2 78 1.2E-51 T 16-09-2016 Spa2297_RS16430 34402d4140841ec86d8e93f5f87ed881 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 4.3E-30 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS07655 48e1a6b4c49234abfa4ba2d04a4cc255 66 SUPERFAMILY SSF46955 8 60 5.13E-6 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS07655 48e1a6b4c49234abfa4ba2d04a4cc255 66 Gene3D G3DSA:1.10.10.10 9 61 9.8E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07655 48e1a6b4c49234abfa4ba2d04a4cc255 66 Pfam PF12728 Helix-turn-helix domain 9 60 4.4E-9 T 16-09-2016 Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 SUPERFAMILY SSF52096 2 253 8.06E-81 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 16-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 PANTHER PTHR11941:SF93 2 254 6.8E-122 T 16-09-2016 Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 Gene3D G3DSA:3.90.226.10 2 247 8.3E-86 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 249 2.5E-67 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS23075 8418c8c46cf9de0ffcf284943685a574 255 PANTHER PTHR11941 2 254 6.8E-122 T 16-09-2016 Spa2297_RS31160 69e8b4ec85e8144c2c6353c0718a2545 357 Pfam PF12902 Ferritin-like 54 248 1.2E-49 T 16-09-2016 Spa2297_RS31160 69e8b4ec85e8144c2c6353c0718a2545 357 PANTHER PTHR34400:SF2 1 355 2.8E-150 T 16-09-2016 Spa2297_RS31160 69e8b4ec85e8144c2c6353c0718a2545 357 Gene3D G3DSA:1.20.1260.10 52 121 7.0E-5 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS31160 69e8b4ec85e8144c2c6353c0718a2545 357 PANTHER PTHR34400 1 355 2.8E-150 T 16-09-2016 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 PANTHER PTHR23135 16 461 9.4E-167 T 16-09-2016 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Pfam PF01225 Mur ligase family, catalytic domain 34 95 1.9E-9 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 400 9.1E-20 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 SUPERFAMILY SSF53623 103 313 4.97E-53 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 459 4.6E-131 T 16-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Gene3D G3DSA:3.40.1390.10 3 81 1.6E-21 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 SUPERFAMILY SSF53244 320 459 1.83E-34 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 SUPERFAMILY SSF63418 3 98 3.14E-21 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Pfam PF08245 Mur ligase middle domain 108 297 3.1E-47 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 460 32.793 T 16-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Gene3D G3DSA:3.40.1190.10 84 313 3.9E-69 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 PANTHER PTHR23135:SF3 16 461 9.4E-167 T 16-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS08545 25b0c8d30965c77b5635acfe7c42de35 471 Gene3D G3DSA:3.90.190.20 319 461 2.2E-42 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 Gene3D G3DSA:3.10.25.10 206 307 7.3E-20 T 16-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 SUPERFAMILY SSF53328 1 204 2.09E-57 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 SUPERFAMILY SSF50486 204 308 4.08E-20 T 16-09-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 Pfam PF02911 Formyl transferase, C-terminal domain 204 306 1.2E-17 T 16-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 PANTHER PTHR11138 1 304 2.4E-79 T 16-09-2016 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 Pfam PF00551 Formyl transferase 1 169 3.5E-31 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS31060 f63599084664fcdf49b5485f131b3e64 315 Gene3D G3DSA:3.40.50.170 1 203 1.3E-53 T 16-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 Gene3D G3DSA:2.10.109.10 147 195 7.7E-27 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 Gene3D G3DSA:2.10.109.10 49 109 7.7E-27 T 16-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 35 194 9.4E-40 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 Pfam PF00717 Peptidase S24-like 55 123 6.5E-12 T 16-09-2016 IPR019759 Peptidase S24/S26A/S26B Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 49 65 3.6E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 99 111 3.6E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 147 166 3.6E-19 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 SUPERFAMILY SSF51306 50 196 4.92E-37 T 16-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C Spa2297_RS23775 b5facb8aee6f2fca6fb5511af22bb15d 257 PANTHER PTHR12383 22 194 6.1E-39 T 16-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 SUPERFAMILY SSF51445 38 428 3.44E-105 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PANTHER PTHR30480 35 66 1.6E-246 T 16-09-2016 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 SUPERFAMILY SSF52279 431 606 4.84E-17 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PANTHER PTHR30480 82 608 1.6E-246 T 16-09-2016 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 431 606 1.3E-16 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 312 329 - T 16-09-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PANTHER PTHR30480:SF5 35 66 1.6E-246 T 16-09-2016 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PANTHER PTHR30480:SF5 82 608 1.6E-246 T 16-09-2016 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PRINTS PR00133 Glycosyl hydrolase family 3 signature 131 147 3.4E-5 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PRINTS PR00133 Glycosyl hydrolase family 3 signature 235 251 3.4E-5 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 PRINTS PR00133 Glycosyl hydrolase family 3 signature 312 330 3.4E-5 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 Gene3D G3DSA:3.20.20.300 87 416 1.0E-110 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 51 391 1.1E-111 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS26540 2c8bbcbac1ab43d76f4c1782f9a8537e 608 Gene3D G3DSA:3.40.50.1700 417 605 5.2E-17 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS01640 04a03f039a1c9fc515337c33a214a7e8 115 Pfam PF05331 Protein of unknown function (DUF742) 6 115 6.1E-36 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS01640 04a03f039a1c9fc515337c33a214a7e8 115 PANTHER PTHR36221 1 115 6.8E-37 T 16-09-2016 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 SUPERFAMILY SSF58014 58 144 2.09E-18 T 16-09-2016 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 SUPERFAMILY SSF51064 149 200 3.27E-13 T 16-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 ProSitePatterns PS01071 grpE protein signature. 155 198 - T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 PANTHER PTHR21237 39 200 4.8E-30 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 PRINTS PR00773 GrpE protein signature 100 115 3.0E-16 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 PRINTS PR00773 GrpE protein signature 72 88 3.0E-16 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 PRINTS PR00773 GrpE protein signature 179 198 3.0E-16 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 PRINTS PR00773 GrpE protein signature 152 167 3.0E-16 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 Gene3D G3DSA:2.30.22.10 147 201 5.0E-18 T 16-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 Hamap MF_01151 Protein GrpE [grpE]. 4 200 15.682 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 Gene3D G3DSA:3.90.20.20 58 141 2.8E-19 T 16-09-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil Spa2297_RS14025 6251c2d12c53f239b8dc4074a6d306fb 202 Pfam PF01025 GrpE 58 200 7.7E-34 T 16-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 PANTHER PTHR10668:SF75 4 490 7.9E-154 T 16-09-2016 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 SUPERFAMILY SSF51905 454 489 1.5E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 SUPERFAMILY SSF51905 2 325 1.5E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 PANTHER PTHR10668 4 490 7.9E-154 T 16-09-2016 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Pfam PF01593 Flavin containing amine oxidoreductase 14 485 9.3E-15 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Gene3D G3DSA:3.50.50.60 215 295 1.6E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Gene3D G3DSA:3.50.50.60 2 54 1.6E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Gene3D G3DSA:3.50.50.60 364 365 1.6E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Gene3D G3DSA:3.50.50.60 459 489 1.6E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS08610 23da25fe1cc72b7c6f2b0099dec48670 498 Gene3D G3DSA:3.50.50.60 87 132 1.6E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28310 da6a37d4834d1d6637c8ec5fda8a69b1 209 Gene3D G3DSA:3.40.50.300 20 192 9.7E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28310 da6a37d4834d1d6637c8ec5fda8a69b1 209 PANTHER PTHR11711:SF117 22 195 1.6E-57 T 16-09-2016 Spa2297_RS28310 da6a37d4834d1d6637c8ec5fda8a69b1 209 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 3.4E-25 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS28310 da6a37d4834d1d6637c8ec5fda8a69b1 209 SUPERFAMILY SSF52540 20 194 2.96E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28310 da6a37d4834d1d6637c8ec5fda8a69b1 209 PANTHER PTHR11711 22 195 1.6E-57 T 16-09-2016 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 Pfam PF00892 EamA-like transporter family 172 302 8.4E-10 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 Pfam PF00892 EamA-like transporter family 27 157 1.2E-10 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 SUPERFAMILY SSF103481 217 306 7.98E-6 T 16-09-2016 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 SUPERFAMILY SSF103481 63 160 3.4E-8 T 16-09-2016 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 PANTHER PTHR12715:SF9 28 307 6.2E-133 T 16-09-2016 Spa2297_RS06105 8674a4c6ad6d602f3e4a580f447fbf0d 308 PANTHER PTHR12715 28 307 6.2E-133 T 16-09-2016 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 SUPERFAMILY SSF56645 2 241 2.36E-89 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 PIRSF PIRSF016578 3 380 9.9E-22 T 16-09-2016 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Gene3D G3DSA:1.10.540.10 1 119 1.8E-43 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 PANTHER PTHR10909:SF186 1 379 2.3E-199 T 16-09-2016 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.6E-37 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 PANTHER PTHR10909 1 379 2.3E-199 T 16-09-2016 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Gene3D G3DSA:2.40.110.10 121 217 2.2E-41 T 16-09-2016 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 5.5E-50 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 SUPERFAMILY SSF47203 228 379 2.09E-57 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.0E-30 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS06665 eeafe6a81f48fc5e876eadccd9693a3b 383 Gene3D G3DSA:1.20.140.10 218 379 1.2E-66 T 16-09-2016 Spa2297_RS04425 9e819e85c601178cdd28c7183f9a9d5a 279 Gene3D G3DSA:3.75.10.10 9 274 1.5E-65 T 16-09-2016 Spa2297_RS04425 9e819e85c601178cdd28c7183f9a9d5a 279 SUPERFAMILY SSF55909 10 275 1.73E-57 T 16-09-2016 Spa2297_RS04425 9e819e85c601178cdd28c7183f9a9d5a 279 Pfam PF02274 Amidinotransferase 17 275 9.7E-15 T 16-09-2016 Spa2297_RS04425 9e819e85c601178cdd28c7183f9a9d5a 279 PANTHER PTHR12737:SF20 3 279 9.9E-120 T 16-09-2016 Spa2297_RS04425 9e819e85c601178cdd28c7183f9a9d5a 279 PANTHER PTHR12737 3 279 9.9E-120 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 Gene3D G3DSA:3.40.50.2300 156 356 9.8E-36 T 16-09-2016 Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 Pfam PF13407 Periplasmic binding protein domain 44 322 8.3E-65 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 PANTHER PTHR30036:SF0 2 369 3.4E-220 T 16-09-2016 Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 PANTHER PTHR30036 2 369 3.4E-220 T 16-09-2016 Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 SUPERFAMILY SSF53822 41 356 3.08E-68 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS10120 a04a596ff148216886555f7c955e76d0 369 Gene3D G3DSA:3.40.50.2300 42 155 2.7E-33 T 16-09-2016 Spa2297_RS23590 01c55211acbc59d90b643d042c4936fa 77 PANTHER PTHR30154:SF29 1 75 9.5E-17 T 16-09-2016 Spa2297_RS23590 01c55211acbc59d90b643d042c4936fa 77 PANTHER PTHR30154 1 75 9.5E-17 T 16-09-2016 Spa2297_RS23590 01c55211acbc59d90b643d042c4936fa 77 SUPERFAMILY SSF54909 2 75 9.92E-15 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS23590 01c55211acbc59d90b643d042c4936fa 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.1E-12 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS23590 01c55211acbc59d90b643d042c4936fa 77 Gene3D G3DSA:3.30.70.920 4 75 2.4E-17 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 SUPERFAMILY SSF54631 282 415 5.43E-23 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 PANTHER PTHR11911 256 431 1.4E-59 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 Gene3D G3DSA:3.10.580.10 281 406 1.2E-18 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 SMART SM00924 180 283 1.4E-34 T 16-09-2016 IPR006668 Magnesium transporter, MgtE intracellular domain Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 PANTHER PTHR11911:SF108 256 431 1.4E-59 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 PANTHER PTHR11911:SF108 197 205 1.4E-59 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 Pfam PF00571 CBS domain 284 345 5.7E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 Pfam PF00571 CBS domain 352 406 9.4E-5 T 16-09-2016 IPR000644 CBS domain Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 Pfam PF03448 MgtE intracellular N domain 180 280 1.9E-26 T 16-09-2016 IPR006668 Magnesium transporter, MgtE intracellular domain Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 Gene3D G3DSA:1.25.60.10 166 278 1.5E-40 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 SUPERFAMILY SSF50346 11 73 5.89E-6 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 SUPERFAMILY SSF158791 169 280 4.32E-30 T 16-09-2016 Spa2297_RS21740 79316a3d8e83163df921a02c72aec1f3 433 PANTHER PTHR11911 197 205 1.4E-59 T 16-09-2016 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 SUPERFAMILY SSF51735 2 147 7.01E-39 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 Gene3D G3DSA:3.30.360.10 131 328 6.4E-49 T 16-09-2016 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 236 4.9E-7 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 PANTHER PTHR22604 1 338 3.1E-104 T 16-09-2016 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 9.7E-19 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 Gene3D G3DSA:3.40.50.720 1 130 2.6E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 PANTHER PTHR22604:SF92 1 338 3.1E-104 T 16-09-2016 Spa2297_RS26480 d2648f21ca6a223b80536320cb55d890 340 SUPERFAMILY SSF55347 126 294 1.96E-23 T 16-09-2016 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 Gene3D G3DSA:1.10.260.40 4 86 6.4E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 SMART SM00530 14 87 1.0E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 PANTHER PTHR35010:SF2 1 288 4.8E-127 T 16-09-2016 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 Pfam PF13560 Helix-turn-helix domain 10 90 8.2E-18 T 16-09-2016 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 SUPERFAMILY SSF47413 34 84 1.72E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20910 a7ac7b8aa80a63b78f655c63a4ff2681 292 PANTHER PTHR35010 1 288 4.8E-127 T 16-09-2016 Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 PANTHER PTHR24220 19 247 1.7E-110 T 16-09-2016 Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 Gene3D G3DSA:3.40.50.300 13 248 3.5E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 SMART SM00382 44 243 8.0E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 Pfam PF00005 ABC transporter 35 185 2.4E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 PANTHER PTHR24220:SF383 19 247 1.7E-110 T 16-09-2016 Spa2297_RS01445 2c132c9e608872c852655015f2a1ed6f 279 SUPERFAMILY SSF52540 16 248 7.88E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11110 03f3fbdb88bd83a4fa30392f7be02e0d 396 PANTHER PTHR21021 155 392 6.8E-75 T 16-09-2016 Spa2297_RS11110 03f3fbdb88bd83a4fa30392f7be02e0d 396 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 383 2.1E-32 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11110 03f3fbdb88bd83a4fa30392f7be02e0d 396 PANTHER PTHR21021:SF21 155 392 6.8E-75 T 16-09-2016 Spa2297_RS11110 03f3fbdb88bd83a4fa30392f7be02e0d 396 SMART SM00331 174 383 2.0E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS11390 33529e9cda3ea8f6aec53d0baecdf2c8 535 Pfam PF00350 Dynamin family 65 194 2.7E-8 T 16-09-2016 IPR022812 Dynamin superfamily Spa2297_RS11390 33529e9cda3ea8f6aec53d0baecdf2c8 535 SUPERFAMILY SSF52540 41 250 1.04E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11390 33529e9cda3ea8f6aec53d0baecdf2c8 535 Gene3D G3DSA:3.40.50.300 56 107 1.2E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11390 33529e9cda3ea8f6aec53d0baecdf2c8 535 Gene3D G3DSA:3.40.50.300 155 240 1.2E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Gene3D G3DSA:3.30.565.10 280 452 2.8E-38 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SMART SM00448 491 603 5.1E-6 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SUPERFAMILY SSF47384 208 294 4.32E-18 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SMART SM00387 338 453 6.8E-33 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SUPERFAMILY SSF55874 282 451 4.58E-39 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Pfam PF00072 Response regulator receiver domain 493 575 1.0E-13 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Gene3D G3DSA:1.10.287.130 217 279 2.8E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 450 1.1E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Gene3D G3DSA:3.40.50.2300 492 591 5.8E-18 T 16-09-2016 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 293 1.1E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SMART SM00388 225 293 3.7E-17 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 SUPERFAMILY SSF52172 489 576 1.35E-17 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PANTHER PTHR24423 221 572 2.2E-83 T 16-09-2016 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PANTHER PTHR24423 165 181 2.2E-83 T 16-09-2016 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PANTHER PTHR24423 16 28 2.2E-83 T 16-09-2016 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 8.2E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 8.2E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 8.2E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS29220 bdeed95427ca38038c54defeded2e226 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 8.2E-14 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 Gene3D G3DSA:3.40.50.720 1 246 2.8E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 195 0.0096 T 16-09-2016 Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.7E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 SUPERFAMILY SSF51735 5 247 1.96E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PANTHER PTHR24322:SF366 151 182 3.5E-57 T 16-09-2016 Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 4.0E-60 T 16-09-2016 Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PANTHER PTHR24322 151 182 3.5E-57 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PANTHER PTHR24322 11 135 3.5E-57 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS14765 16183278f04183cf8452ad2248fbe1c5 250 PANTHER PTHR24322:SF366 11 135 3.5E-57 T 16-09-2016 Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 8.4E-110 T 16-09-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 SUPERFAMILY SSF51730 15 301 4.9E-93 T 16-09-2016 IPR029041 FAD-linked oxidoreductase-like Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 PANTHER PTHR21091 158 301 1.4E-36 T 16-09-2016 Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 PANTHER PTHR21091:SF31 158 301 1.4E-36 T 16-09-2016 Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 1.5E-93 T 16-09-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 Spa2297_RS08620 ea89bf416b2f7a8664bf9d60bb914f22 307 Gene3D G3DSA:3.20.20.220 12 302 1.2E-103 T 16-09-2016 IPR029041 FAD-linked oxidoreductase-like Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 PANTHER PTHR11599 7 274 2.1E-156 T 16-09-2016 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 Gene3D G3DSA:3.60.20.10 54 260 1.4E-56 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 PRINTS PR00141 Proteasome component signature 61 76 2.3E-6 T 16-09-2016 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 PRINTS PR00141 Proteasome component signature 199 210 2.3E-6 T 16-09-2016 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 PRINTS PR00141 Proteasome component signature 188 199 2.3E-6 T 16-09-2016 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 8.3E-119 T 16-09-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UniPathway: UPA00997 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 PANTHER PTHR11599:SF58 7 274 2.1E-156 T 16-09-2016 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 Pfam PF00227 Proteasome subunit 52 231 6.4E-39 T 16-09-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 50.335 T 16-09-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UniPathway: UPA00997 Spa2297_RS06375 4c8e7ce49e97ed1ccc688b542687f5ad 281 SUPERFAMILY SSF56235 21 263 1.12E-59 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS30460 bbfc4877ac176e0e90f1c078ea4bd4f7 311 Pfam PF01435 Peptidase family M48 102 200 4.9E-16 T 16-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spa2297_RS30460 bbfc4877ac176e0e90f1c078ea4bd4f7 311 Gene3D G3DSA:3.30.2010.10 117 183 1.2E-16 T 16-09-2016 Spa2297_RS16060 51a38db86d2eded660dfdd86a30473fc 296 Pfam PF04909 Amidohydrolase 22 293 8.4E-40 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS16060 51a38db86d2eded660dfdd86a30473fc 296 Gene3D G3DSA:3.20.20.140 20 293 1.0E-59 T 16-09-2016 Spa2297_RS16060 51a38db86d2eded660dfdd86a30473fc 296 PANTHER PTHR21240:SF12 21 294 5.0E-19 T 16-09-2016 Spa2297_RS16060 51a38db86d2eded660dfdd86a30473fc 296 PANTHER PTHR21240 21 294 5.0E-19 T 16-09-2016 Spa2297_RS16060 51a38db86d2eded660dfdd86a30473fc 296 SUPERFAMILY SSF51556 22 293 5.37E-55 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS25485 2701e5367c544885f58b7bf1d9ad20a4 370 PANTHER PTHR12169:SF0 94 363 3.4E-77 T 16-09-2016 Spa2297_RS25485 2701e5367c544885f58b7bf1d9ad20a4 370 Gene3D G3DSA:3.40.50.300 33 230 8.8E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25485 2701e5367c544885f58b7bf1d9ad20a4 370 PANTHER PTHR12169 94 363 3.4E-77 T 16-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 Spa2297_RS25485 2701e5367c544885f58b7bf1d9ad20a4 370 SUPERFAMILY SSF52540 103 219 5.2E-8 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25485 2701e5367c544885f58b7bf1d9ad20a4 370 Pfam PF03969 AFG1-like ATPase 60 249 1.2E-40 T 16-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 Spa2297_RS33120 67bf306a22a16a093dee5e40ca5d263f 77 PANTHER PTHR23023:SF55 5 77 4.7E-18 T 16-09-2016 Spa2297_RS33120 67bf306a22a16a093dee5e40ca5d263f 77 PANTHER PTHR23023 5 77 4.7E-18 T 16-09-2016 Spa2297_RS04685 13e2c7f9ddd17c664b2bbd4fce70b0cf 155 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 15 135 2.4E-19 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS04685 13e2c7f9ddd17c664b2bbd4fce70b0cf 155 Gene3D G3DSA:3.30.530.20 14 134 1.9E-17 T 16-09-2016 IPR023393 START-like domain Spa2297_RS04685 13e2c7f9ddd17c664b2bbd4fce70b0cf 155 SUPERFAMILY SSF55961 15 142 5.08E-24 T 16-09-2016 Spa2297_RS17410 1f8d2417bc45bdbbe4525927331b20c6 227 Pfam PF10935 Protein of unknown function (DUF2637) 6 117 3.9E-23 T 16-09-2016 IPR021235 Protein of unknown function DUF2637 Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 Gene3D G3DSA:3.40.50.300 54 272 2.1E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 SMART SM00382 68 251 2.0E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 PANTHER PTHR24220 43 257 2.7E-92 T 16-09-2016 Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 SUPERFAMILY SSF52540 54 256 3.7E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 Pfam PF00005 ABC transporter 59 193 1.0E-16 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 PANTHER PTHR24220:SF117 43 257 2.7E-92 T 16-09-2016 Spa2297_RS12935 058d020dc9985dc0944c4ce72dcca5de 297 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 260 277 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 48 67 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 280 306 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 362 386 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 397 407 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00463 E-class P450 group I signature 407 430 4.9E-18 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 SUPERFAMILY SSF48264 18 458 2.49E-97 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 Gene3D G3DSA:1.10.630.10 18 458 2.9E-103 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00385 P450 superfamily signature 398 407 8.3E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00385 P450 superfamily signature 271 288 8.3E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PRINTS PR00385 P450 superfamily signature 323 334 8.3E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 Pfam PF00067 Cytochrome P450 27 433 1.1E-66 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PANTHER PTHR24291 49 450 3.8E-76 T 16-09-2016 Spa2297_RS22095 d168e838e34db5774948218fb36012ce 458 PANTHER PTHR24291:SF46 49 450 3.8E-76 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 Gene3D G3DSA:2.40.10.10 198 278 1.3E-13 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 Pfam PF13365 Trypsin-like peptidase domain 215 352 8.0E-21 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 SUPERFAMILY SSF50494 191 374 1.86E-32 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 Pfam PF02674 Colicin V production protein 4 146 2.3E-15 T 16-09-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PANTHER PTHR22939 35 372 1.0E-92 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PANTHER PTHR22939:SF106 35 372 1.0E-92 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 Gene3D G3DSA:2.40.10.10 279 378 5.3E-13 T 16-09-2016 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PRINTS PR00834 HtrA/DegQ protease family signature 323 340 1.4E-8 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PRINTS PR00834 HtrA/DegQ protease family signature 223 235 1.4E-8 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PRINTS PR00834 HtrA/DegQ protease family signature 345 362 1.4E-8 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS09045 468d1e96f1463e41911ba3cbb7a055b5 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 1.4E-8 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS04450 b100803dda627051c4dc80c591c31b67 340 PANTHER PTHR10366:SF340 1 325 5.4E-100 T 16-09-2016 Spa2297_RS04450 b100803dda627051c4dc80c591c31b67 340 Pfam PF13460 NAD(P)H-binding 4 107 1.2E-10 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04450 b100803dda627051c4dc80c591c31b67 340 PANTHER PTHR10366 1 325 5.4E-100 T 16-09-2016 Spa2297_RS04450 b100803dda627051c4dc80c591c31b67 340 SUPERFAMILY SSF51735 1 309 5.14E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04450 b100803dda627051c4dc80c591c31b67 340 Gene3D G3DSA:3.40.50.720 2 300 8.2E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 Pfam PF01553 Acyltransferase 21 151 5.1E-21 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 SMART SM00563 35 154 1.8E-34 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 PANTHER PTHR10434 6 222 1.3E-80 T 16-09-2016 Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 Gene3D G3DSA:3.40.1130.10 8 207 2.3E-34 T 16-09-2016 Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 SUPERFAMILY SSF69593 6 220 3.53E-48 T 16-09-2016 Spa2297_RS06010 3fed312d191b824672375e3ece173da5 223 PANTHER PTHR10434:SF21 6 222 1.3E-80 T 16-09-2016 Spa2297_RS20485 4ce47d277133a7263d8352fe8d56da52 162 Pfam PF04134 Protein of unknown function, DUF393 18 114 2.0E-11 T 16-09-2016 IPR007263 Protein of unknown function DUF393 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 PIRSF PIRSF001296 8 222 1.6E-66 T 16-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 218 32.721 T 16-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 216 1.1E-45 T 16-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 PANTHER PTHR30042:SF2 6 223 1.7E-77 T 16-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 Pfam PF02669 K+-transporting ATPase, c chain 14 216 3.6E-64 T 16-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Spa2297_RS14150 cca04a32db19447132fc0928ffba8d2c 223 PANTHER PTHR30042 6 223 1.7E-77 T 16-09-2016 Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 SMART SM01007 20 194 7.8E-59 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 PANTHER PTHR22789 7 224 8.5E-86 T 16-09-2016 Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 21 193 5.7E-49 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 SUPERFAMILY SSF53639 13 225 4.12E-64 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 PANTHER PTHR22789:SF0 7 224 8.5E-86 T 16-09-2016 Spa2297_RS07365 cdc1f3d9c6bdf6b192e813cf86e610fd 226 Gene3D G3DSA:3.40.225.10 14 225 1.2E-71 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 Gene3D G3DSA:3.40.190.10 148 334 8.6E-39 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 PANTHER PTHR30061:SF1 1 401 5.9E-65 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 PANTHER PTHR30061 1 401 5.9E-65 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 Pfam PF13416 Bacterial extracellular solute-binding protein 40 338 1.1E-42 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 SUPERFAMILY SSF53850 33 396 3.93E-66 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 Gene3D G3DSA:3.40.190.10 33 147 3.7E-22 T 16-09-2016 Spa2297_RS14845 980f61f61c426c6e7d58bdcc656b76ba 405 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 128 145 - T 16-09-2016 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 Gene3D G3DSA:2.120.10.30 122 323 1.3E-15 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 PANTHER PTHR11731:SF75 28 608 2.4E-117 T 16-09-2016 Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 Pfam PF00326 Prolyl oligopeptidase family 407 608 8.4E-39 T 16-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 Gene3D G3DSA:3.40.50.1820 347 608 2.8E-74 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 Gene3D G3DSA:3.40.50.1820 53 92 2.8E-74 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 SUPERFAMILY SSF53474 358 608 1.87E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 PANTHER PTHR11731 28 608 2.4E-117 T 16-09-2016 Spa2297_RS17770 6d7cb437e18dbb3f5816319075ba0814 612 SUPERFAMILY SSF82171 42 332 1.33E-23 T 16-09-2016 Spa2297_RS25300 d216330f4c0f6a8640e5883e8261fe6b 371 SUPERFAMILY SSF89372 35 332 3.14E-25 T 16-09-2016 Spa2297_RS13435 dc46a5b5b8b10c751e61d64f627ed5af 183 Pfam PF04417 Protein of unknown function (DUF501) 36 154 1.8E-36 T 16-09-2016 IPR007511 Protein of unknown function DUF501 Spa2297_RS13435 dc46a5b5b8b10c751e61d64f627ed5af 183 PANTHER PTHR37163 1 173 3.0E-54 T 16-09-2016 Spa2297_RS13435 dc46a5b5b8b10c751e61d64f627ed5af 183 PANTHER PTHR37163:SF1 1 173 3.0E-54 T 16-09-2016 Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 Gene3D G3DSA:3.90.1150.10 237 349 6.6E-15 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 SUPERFAMILY SSF53383 15 348 1.83E-60 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 Pfam PF00266 Aminotransferase class-V 17 291 1.1E-24 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 Gene3D G3DSA:3.40.640.10 15 236 1.1E-43 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 PANTHER PTHR21152:SF21 16 353 7.2E-47 T 16-09-2016 Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 PIRSF PIRSF000524 15 366 1.8E-61 T 16-09-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 Spa2297_RS07430 f83455ec8f1d49a95baed43704427060 375 PANTHER PTHR21152 16 353 7.2E-47 T 16-09-2016 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 Gene3D G3DSA:1.10.530.10 46 104 3.2E-58 T 16-09-2016 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 Gene3D G3DSA:1.10.530.10 168 248 3.2E-58 T 16-09-2016 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 PANTHER PTHR22595 46 248 1.1E-96 T 16-09-2016 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 Gene3D G3DSA:3.30.20.10 112 167 5.8E-26 T 16-09-2016 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 PIRSF PIRSF001060 2 248 1.5E-86 T 16-09-2016 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 SUPERFAMILY SSF53955 44 248 4.22E-72 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS31130 58b4f22d07135fed16d35f046ce0c20d 248 Pfam PF00182 Chitinase class I 46 248 2.3E-49 T 16-09-2016 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 Pfam PF00072 Response regulator receiver domain 4 115 3.3E-21 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 PANTHER PTHR26402 2 210 4.0E-87 T 16-09-2016 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 SUPERFAMILY SSF46894 136 213 4.08E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.0E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 Gene3D G3DSA:3.40.50.2300 1 122 2.3E-32 T 16-09-2016 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 1.2E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 Gene3D G3DSA:1.10.10.10 123 213 1.0E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 SUPERFAMILY SSF52172 1 131 1.14E-28 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 SMART SM00448 2 114 1.4E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 PANTHER PTHR26402:SF151 2 210 4.0E-87 T 16-09-2016 Spa2297_RS22720 b78cc3219221547f06e61470e021368e 213 SMART SM00421 151 208 7.6E-24 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 187 7.6E-20 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 PANTHER PTHR18901 1 209 4.8E-45 T 16-09-2016 Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 Gene3D G3DSA:1.10.150.240 27 70 1.1E-6 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 187 3.5E-18 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 SUPERFAMILY SSF56784 12 205 3.31E-42 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 PANTHER PTHR18901:SF2 1 209 4.8E-45 T 16-09-2016 Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 Gene3D G3DSA:3.40.50.1000 77 209 2.0E-38 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09795 f846d8a296c6158871b56fe37e74cf28 221 ProSitePatterns PS01228 Hypothetical cof family signature 1. 13 24 - T 16-09-2016 IPR000150 Cof protein GO:0016787 Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 Gene3D G3DSA:3.60.15.10 26 234 2.4E-45 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 PANTHER PTHR23131 27 277 3.5E-80 T 16-09-2016 Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 PANTHER PTHR23131:SF4 27 277 3.5E-80 T 16-09-2016 Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 SMART SM00849 39 204 1.8E-25 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 5.3E-15 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS17860 a27effab4c879819be04cd34c24e220a 280 SUPERFAMILY SSF56281 29 277 3.78E-48 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 PANTHER PTHR23070 237 318 1.0E-75 T 16-09-2016 Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 PANTHER PTHR23070:SF29 237 318 1.0E-75 T 16-09-2016 Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 PANTHER PTHR23070 141 221 1.0E-75 T 16-09-2016 Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 SMART SM00382 178 315 4.7E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 Gene3D G3DSA:3.40.50.300 180 306 2.7E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 182 312 1.9E-11 T 16-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 PANTHER PTHR23070:SF29 141 221 1.0E-75 T 16-09-2016 Spa2297_RS06790 c212360a7751d9e513d00d20fa392a9f 364 SUPERFAMILY SSF52540 176 314 3.46E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 Pfam PF07690 Major Facilitator Superfamily 7 346 2.4E-20 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 Gene3D G3DSA:1.20.1250.20 5 185 1.2E-19 T 16-09-2016 Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 Gene3D G3DSA:1.20.1250.20 200 402 2.8E-13 T 16-09-2016 Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 PANTHER PTHR11662:SF283 12 353 1.4E-23 T 16-09-2016 Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 SUPERFAMILY SSF103473 10 401 2.22E-38 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31565 408dd169fed88a9ffe22270e0406ebd1 421 PANTHER PTHR11662 12 353 1.4E-23 T 16-09-2016 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 PANTHER PTHR19959 728 959 6.5E-21 T 16-09-2016 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 SUPERFAMILY SSF48452 736 848 3.16E-11 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 SUPERFAMILY SSF48452 812 929 5.55E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 PANTHER PTHR19959:SF128 728 959 6.5E-21 T 16-09-2016 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 SUPERFAMILY SSF53474 33 160 3.24E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Gene3D G3DSA:1.25.40.10 738 927 6.6E-16 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Gene3D G3DSA:3.40.50.1820 151 211 1.6E-10 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Gene3D G3DSA:3.40.50.1820 2 112 1.6E-10 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Pfam PF13374 Tetratricopeptide repeat 859 888 0.0028 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 SUPERFAMILY SSF52540 278 476 1.05E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Gene3D G3DSA:3.40.50.300 286 380 5.3E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Pfam PF13424 Tetratricopeptide repeat 789 847 4.1E-8 T 16-09-2016 Spa2297_RS28545 06d83f5ce78c6b54a90aa08640ba7fe9 964 Pfam PF00931 NB-ARC domain 288 474 3.7E-8 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 496 513 - T 16-09-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Pfam PF00342 Phosphoglucose isomerase 53 540 3.9E-215 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Gene3D G3DSA:3.40.50.10490 296 505 3.4E-128 T 16-09-2016 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Gene3D G3DSA:3.40.50.10490 11 99 3.4E-128 T 16-09-2016 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Gene3D G3DSA:1.10.1390.10 506 546 8.4E-20 T 16-09-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Gene3D G3DSA:3.40.50.10490 100 293 1.7E-82 T 16-09-2016 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 523 41.099 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 482 496 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 496 509 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 282 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 341 362 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 151 170 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 464 482 8.4E-54 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 SUPERFAMILY SSF53697 8 547 1.92E-205 T 16-09-2016 Spa2297_RS27690 02ec3497f7d3a2e4c6a3b2c168c4aefe 550 PANTHER PTHR11469 1 550 0.0 T 16-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 Gene3D G3DSA:3.30.300.20 17 106 6.2E-31 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 SUPERFAMILY SSF54821 106 205 3.79E-37 T 16-09-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 PANTHER PTHR11760 2 242 1.1E-122 T 16-09-2016 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 16-09-2016 IPR018280 Ribosomal protein S3, conserved site Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 2.3E-92 T 16-09-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.3E-36 T 16-09-2016 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 SMART SM00322 59 124 2.5E-7 T 16-09-2016 IPR004087 K Homology domain GO:0003676 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 Pfam PF07650 KH domain 38 109 1.5E-18 T 16-09-2016 IPR004044 K Homology domain, type 2 GO:0003723 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 SUPERFAMILY SSF54814 2 105 5.23E-34 T 16-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 Gene3D G3DSA:3.30.1140.32 107 206 3.5E-42 T 16-09-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.472 T 16-09-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19825 447dcc03d733831bfa1da48230899924 276 PANTHER PTHR11760:SF19 2 242 1.1E-122 T 16-09-2016 Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 Gene3D G3DSA:3.30.450.30 69 146 2.5E-7 T 16-09-2016 Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 Gene3D G3DSA:3.30.450.30 11 50 1.6E-4 T 16-09-2016 Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 Pfam PF03259 Roadblock/LC7 domain 63 120 1.4E-5 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 SMART SM00960 17 122 4.1E-11 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 SUPERFAMILY SSF103196 11 150 1.92E-18 T 16-09-2016 Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 PANTHER PTHR36222 63 161 4.9E-54 T 16-09-2016 Spa2297_RS22355 ee0e12dae0ff7d1b22cabad5c45fa1d9 179 PANTHER PTHR36222 5 47 4.9E-54 T 16-09-2016 Spa2297_RS04750 3cce9a1c7692da544c53af6934216f2c 172 Pfam PF15589 Immunity protein 21 11 159 4.7E-60 T 16-09-2016 IPR028961 Immunity protein 21 Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 SMART SM00458 496 633 4.8E-10 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 416 477 2.0E-15 T 16-09-2016 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 578 632 1.7E-11 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 495 572 1.4E-18 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 SUPERFAMILY SSF50370 491 633 3.69E-39 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Gene3D G3DSA:3.20.20.80 68 409 4.3E-111 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 PANTHER PTHR11069 46 486 4.7E-94 T 16-09-2016 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 89 413 3.9E-32 T 16-09-2016 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Gene3D G3DSA:2.60.40.1180 410 480 2.9E-19 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 Gene3D G3DSA:2.80.10.50 495 632 1.5E-34 T 16-09-2016 Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 SUPERFAMILY SSF51011 411 479 4.68E-9 T 16-09-2016 Spa2297_RS00525 2fe07131df911c8e1ab509f63d973c34 634 SUPERFAMILY SSF51445 87 417 2.11E-68 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 SUPERFAMILY SSF46955 1 112 2.42E-29 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 Gene3D G3DSA:1.10.1660.10 55 126 5.2E-11 T 16-09-2016 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 PANTHER PTHR30204 1 113 2.8E-25 T 16-09-2016 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 SMART SM00422 1 69 3.3E-26 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.1E-10 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.1E-10 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.1E-10 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 Gene3D G3DSA:1.10.1660.10 1 54 4.0E-25 T 16-09-2016 Spa2297_RS22985 148b5ef34e2a3a2d774ee2b5887ef919 132 Pfam PF13411 MerR HTH family regulatory protein 1 61 1.3E-20 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 Gene3D G3DSA:3.40.190.10 172 359 3.6E-44 T 16-09-2016 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 Pfam PF13416 Bacterial extracellular solute-binding protein 60 363 5.4E-38 T 16-09-2016 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 Gene3D G3DSA:3.40.190.10 38 171 3.8E-17 T 16-09-2016 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 PANTHER PTHR30061 1 428 9.4E-79 T 16-09-2016 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 SUPERFAMILY SSF53850 29 429 8.8E-78 T 16-09-2016 Spa2297_RS12725 8a56e6aa26667dc5f0870207f0d66186 432 PANTHER PTHR30061:SF1 1 428 9.4E-79 T 16-09-2016 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 Gene3D G3DSA:1.10.1740.10 74 147 4.2E-17 T 16-09-2016 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 Pfam PF08281 Sigma-70, region 4 175 225 2.5E-14 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 83 227 2.7E-23 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 PANTHER PTHR30173 75 227 4.2E-32 T 16-09-2016 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 Gene3D G3DSA:1.10.10.10 168 227 8.1E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 SUPERFAMILY SSF88659 166 227 1.76E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 Pfam PF04542 Sigma-70 region 2 84 147 1.1E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 SUPERFAMILY SSF88946 75 160 1.02E-14 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20775 75af057ac93a710b3e30b2de2916a20b 246 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 74 229 1.1E-61 T 16-09-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 Spa2297_RS14405 fce465fdd339fc53f43fc268cef7d2e1 441 SUPERFAMILY SSF109854 152 315 1.1E-16 T 16-09-2016 Spa2297_RS14405 fce465fdd339fc53f43fc268cef7d2e1 441 Pfam PF13490 Putative zinc-finger 83 112 4.4E-5 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS14405 fce465fdd339fc53f43fc268cef7d2e1 441 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 163 309 1.8E-5 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS07170 2fb2ec25f5ae3502854b7168a5404929 233 Pfam PF01464 Transglycosylase SLT domain 158 228 8.2E-8 T 16-09-2016 IPR008258 Transglycosylase SLT domain 1 Spa2297_RS07170 2fb2ec25f5ae3502854b7168a5404929 233 SUPERFAMILY SSF53955 129 228 9.64E-16 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS07170 2fb2ec25f5ae3502854b7168a5404929 233 Gene3D G3DSA:1.10.530.10 139 229 5.9E-11 T 16-09-2016 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 SUPERFAMILY SSF51445 96 330 2.83E-22 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 Pfam PF02638 Glycosyl hydrolase-like 10 42 354 9.5E-83 T 16-09-2016 IPR003790 Glycosyl hydrolase-like 10 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 Gene3D G3DSA:3.20.20.80 125 212 6.1E-4 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 Gene3D G3DSA:3.20.20.80 244 300 6.1E-4 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 PANTHER PTHR30032 234 355 5.3E-80 T 16-09-2016 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 PANTHER PTHR30032:SF2 234 355 5.3E-80 T 16-09-2016 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 PANTHER PTHR30032 28 212 5.3E-80 T 16-09-2016 Spa2297_RS06115 e05d0f0548c2aa8479aaa5d4a3ed0ff2 413 PANTHER PTHR30032:SF2 28 212 5.3E-80 T 16-09-2016 Spa2297_RS21290 68dd4936cf432e3ee8a9efd8a5c111ba 460 PANTHER PTHR21716 87 459 8.3E-76 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS21290 68dd4936cf432e3ee8a9efd8a5c111ba 460 Pfam PF01594 Domain of unknown function DUF20 87 411 4.6E-59 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 Pfam PF13560 Helix-turn-helix domain 34 92 9.0E-16 T 16-09-2016 Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 PANTHER PTHR10245:SF20 4 308 3.4E-67 T 16-09-2016 Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 PANTHER PTHR10245 4 308 3.4E-67 T 16-09-2016 Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 SMART SM00530 36 93 5.3E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 SUPERFAMILY SSF47413 27 88 3.49E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS30185 5437192ec30b3a154a2e959bc7f865c1 310 Gene3D G3DSA:1.10.260.40 29 91 1.1E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25070 2e6a8fee5c7070f4752f0f7ce9a73427 130 Pfam PF04472 Protein of unknown function (DUF552) 47 117 5.2E-18 T 16-09-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 Spa2297_RS25070 2e6a8fee5c7070f4752f0f7ce9a73427 130 PANTHER PTHR35798 1 125 2.1E-32 T 16-09-2016 Spa2297_RS25070 2e6a8fee5c7070f4752f0f7ce9a73427 130 PANTHER PTHR35798:SF1 1 125 2.1E-32 T 16-09-2016 Spa2297_RS25070 2e6a8fee5c7070f4752f0f7ce9a73427 130 Hamap MF_01197 Cell division protein SepF [sepF]. 11 125 14.193 T 16-09-2016 IPR023052 Cell division protein SepF GO:0090529 Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 Gene3D G3DSA:3.40.30.10 4 84 3.3E-20 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 Pfam PF00462 Glutaredoxin 5 59 4.6E-12 T 16-09-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 SUPERFAMILY SSF52833 4 74 1.72E-15 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 83 6.8E-27 T 16-09-2016 IPR011915 Glutaredoxin-like protein, actinobacteria Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 PANTHER PTHR34386:SF1 3 83 4.8E-17 T 16-09-2016 Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 PANTHER PTHR34386 3 83 4.8E-17 T 16-09-2016 Spa2297_RS21905 8eee28d3ff70a28812ba0d156ed39296 85 ProSitePatterns PS00194 Thioredoxin family active site. 5 23 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 268 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 PANTHER PTHR11986 15 421 7.4E-188 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 Gene3D G3DSA:3.90.1150.10 303 414 5.1E-28 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 SUPERFAMILY SSF53383 41 413 1.53E-108 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 Gene3D G3DSA:3.40.640.10 71 302 1.4E-83 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 PANTHER PTHR11986:SF75 15 421 7.4E-188 T 16-09-2016 Spa2297_RS04690 a5da734ac96892ef7034206798c67dbc 422 Pfam PF00202 Aminotransferase class-III 41 413 6.5E-96 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS14990 f6c984f2803a69909fb0b61facbb7f9c 534 PANTHER PTHR35861 2 534 4.2E-250 T 16-09-2016 Spa2297_RS14990 f6c984f2803a69909fb0b61facbb7f9c 534 Pfam PF04984 Phage tail sheath protein 1 523 2.8E-113 T 16-09-2016 IPR007067 Tail sheath protein Spa2297_RS14990 f6c984f2803a69909fb0b61facbb7f9c 534 PANTHER PTHR35861:SF1 2 534 4.2E-250 T 16-09-2016 Spa2297_RS00470 df2c442acbd8d24a4a52af6af909434e 455 Pfam PF00781 Diacylglycerol kinase catalytic domain 132 250 3.8E-17 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS00470 df2c442acbd8d24a4a52af6af909434e 455 PANTHER PTHR12358 120 273 5.1E-12 T 16-09-2016 Spa2297_RS00470 df2c442acbd8d24a4a52af6af909434e 455 PANTHER PTHR12358:SF43 120 273 5.1E-12 T 16-09-2016 Spa2297_RS00470 df2c442acbd8d24a4a52af6af909434e 455 Gene3D G3DSA:3.40.50.10330 173 241 1.4E-6 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00470 df2c442acbd8d24a4a52af6af909434e 455 SUPERFAMILY SSF111331 128 427 1.94E-43 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 Gene3D G3DSA:1.10.10.10 27 177 6.7E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 PANTHER PTHR33164:SF4 14 177 6.8E-29 T 16-09-2016 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 PANTHER PTHR33164 14 177 6.8E-29 T 16-09-2016 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 Pfam PF12802 MarR family 67 125 8.0E-14 T 16-09-2016 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 118 1.1E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 152 172 1.1E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 138 1.1E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 SUPERFAMILY SSF46785 34 177 3.32E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03660 ce7a83b536446d5d0c67f136aaf3a192 185 SMART SM00347 61 162 1.0E-18 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS04055 40825f71c44532ff21028bceea71c052 272 Gene3D G3DSA:3.40.50.150 74 230 1.4E-40 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04055 40825f71c44532ff21028bceea71c052 272 PANTHER PTHR10108:SF911 74 226 1.3E-41 T 16-09-2016 Spa2297_RS04055 40825f71c44532ff21028bceea71c052 272 PANTHER PTHR10108 74 226 1.3E-41 T 16-09-2016 Spa2297_RS04055 40825f71c44532ff21028bceea71c052 272 Pfam PF13847 Methyltransferase domain 77 191 1.1E-25 T 16-09-2016 IPR025714 Methyltransferase domain Spa2297_RS04055 40825f71c44532ff21028bceea71c052 272 SUPERFAMILY SSF53335 64 229 5.16E-39 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15650 05ed39ec9938f628e63b5137039e6cd5 345 Gene3D G3DSA:2.70.70.10 189 339 1.7E-42 T 16-09-2016 Spa2297_RS15650 05ed39ec9938f628e63b5137039e6cd5 345 SUPERFAMILY SSF51261 157 338 9.42E-43 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS15650 05ed39ec9938f628e63b5137039e6cd5 345 PANTHER PTHR21666 140 344 9.6E-42 T 16-09-2016 Spa2297_RS15650 05ed39ec9938f628e63b5137039e6cd5 345 PANTHER PTHR21666:SF200 140 344 9.6E-42 T 16-09-2016 Spa2297_RS15650 05ed39ec9938f628e63b5137039e6cd5 345 Pfam PF01551 Peptidase family M23 239 334 4.6E-25 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 Hamap MF_01830 UPF0317 protein . 24 276 53.296 T 16-09-2016 IPR016938 Uncharacterised protein family UPF0317 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 SUPERFAMILY SSF160920 20 269 3.01E-110 T 16-09-2016 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 PANTHER PTHR32022 10 275 3.2E-152 T 16-09-2016 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 Pfam PF07286 Protein of unknown function (DUF1445) 126 268 1.0E-63 T 16-09-2016 IPR009906 Protein of unknown function DUF1445 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 PIRSF PIRSF029755 12 277 3.1E-120 T 16-09-2016 IPR016938 Uncharacterised protein family UPF0317 Spa2297_RS05255 bde899fa3c1313b7e4d7aa0ad52aaac5 277 Gene3D G3DSA:3.40.1640.10 19 178 1.5E-67 T 16-09-2016 Spa2297_RS07525 87f97d9f74a2d7e9e479820979dda5bd 299 PANTHER PTHR32243:SF42 26 299 4.9E-145 T 16-09-2016 Spa2297_RS07525 87f97d9f74a2d7e9e479820979dda5bd 299 Gene3D G3DSA:1.10.3720.10 27 286 5.7E-63 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07525 87f97d9f74a2d7e9e479820979dda5bd 299 PANTHER PTHR32243 26 299 4.9E-145 T 16-09-2016 Spa2297_RS07525 87f97d9f74a2d7e9e479820979dda5bd 299 SUPERFAMILY SSF161098 34 299 4.58E-68 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07525 87f97d9f74a2d7e9e479820979dda5bd 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 288 1.8E-17 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 Pfam PF07336 Putative stress-induced transcription regulator 9 135 4.2E-17 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 PANTHER PTHR35525:SF1 5 190 8.8E-77 T 16-09-2016 Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 SUPERFAMILY SSF160904 8 182 4.18E-39 T 16-09-2016 Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 PANTHER PTHR35525 5 190 8.8E-77 T 16-09-2016 Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 Gene3D G3DSA:1.10.3300.10 8 184 1.6E-47 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS22245 b289ed23e65676758b5c0b3867cdc896 209 Pfam PF11706 CGNR zinc finger 141 183 5.3E-15 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 PIRSF PIRSF028754 12 312 1.2E-113 T 16-09-2016 IPR008492 Protein of unknown function DUF774 Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 SUPERFAMILY SSF159659 25 277 1.16E-72 T 16-09-2016 Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 Pfam PF09754 PAC2 family 35 253 1.8E-40 T 16-09-2016 IPR019151 Proteasome assembly chaperone 2 Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 Gene3D G3DSA:1.10.287.100 237 275 2.3E-9 T 16-09-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 PANTHER PTHR42301 1 311 2.7E-206 T 16-09-2016 Spa2297_RS08100 478b73ae7b783726dac540de157c4c94 312 PANTHER PTHR42301:SF1 1 311 2.7E-206 T 16-09-2016 Spa2297_RS12370 6c0e5a487e69b22ceb0d1d101b837873 263 Pfam PF06182 ABC-2 family transporter protein 30 262 6.8E-69 T 16-09-2016 IPR010390 Protein of unknown function DUF990 Spa2297_RS12370 6c0e5a487e69b22ceb0d1d101b837873 263 PANTHER PTHR36833:SF1 1 263 2.0E-130 T 16-09-2016 Spa2297_RS12370 6c0e5a487e69b22ceb0d1d101b837873 263 PANTHER PTHR36833 1 263 2.0E-130 T 16-09-2016 Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 PANTHER PTHR30582 115 213 1.4E-13 T 16-09-2016 Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 Gene3D G3DSA:2.40.440.10 121 225 6.2E-11 T 16-09-2016 Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 SUPERFAMILY SSF47090 48 96 6.75E-5 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 PANTHER PTHR30582:SF2 115 213 1.4E-13 T 16-09-2016 Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 SUPERFAMILY SSF141523 114 225 8.24E-21 T 16-09-2016 Spa2297_RS30035 467ed132f0bfac2f74b514fbba99fa4a 231 Pfam PF03734 L,D-transpeptidase catalytic domain 115 224 3.3E-13 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS14525 9b8fd52987baf49416e73a95e005f28f 322 PANTHER PTHR22911:SF37 39 314 5.3E-87 T 16-09-2016 Spa2297_RS14525 9b8fd52987baf49416e73a95e005f28f 322 PANTHER PTHR22911 39 314 5.3E-87 T 16-09-2016 Spa2297_RS14525 9b8fd52987baf49416e73a95e005f28f 322 SUPERFAMILY SSF103481 72 165 9.68E-7 T 16-09-2016 Spa2297_RS14525 9b8fd52987baf49416e73a95e005f28f 322 Pfam PF00892 EamA-like transporter family 173 302 1.3E-15 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS14525 9b8fd52987baf49416e73a95e005f28f 322 SUPERFAMILY SSF103481 212 306 6.28E-9 T 16-09-2016 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 Gene3D G3DSA:3.20.20.80 8 433 3.8E-131 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 SUPERFAMILY SSF51445 8 432 1.43E-136 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 16-09-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PRINTS PR00131 Glycosyl hydrolase family 1 signature 345 353 3.2E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 416 3.2E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 370 3.2E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 397 3.2E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PRINTS PR00131 Glycosyl hydrolase family 1 signature 270 284 3.2E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PANTHER PTHR10353 8 433 1.4E-165 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 Pfam PF00232 Glycosyl hydrolase family 1 8 433 2.7E-117 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 PANTHER PTHR10353:SF36 8 433 1.4E-165 T 16-09-2016 Spa2297_RS10660 b02d80b0d134130a768b956d468b06a6 439 TIGRFAM TIGR03356 BGL: beta-galactosidase 9 426 4.4E-148 T 16-09-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PANTHER PTHR11406 2 403 9.2E-188 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 Gene3D G3DSA:3.40.50.1270 185 391 4.4E-77 T 16-09-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 40.241 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PIRSF PIRSF000724 1 403 2.1E-129 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 Pfam PF00162 Phosphoglycerate kinase 12 393 1.5E-142 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 SUPERFAMILY SSF53748 5 403 8.6E-140 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 16-09-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 2.0E-79 T 16-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS07845 f76a58c058367053698beb8a00a72aaa 403 Gene3D G3DSA:3.40.50.1260 5 184 9.3E-63 T 16-09-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 SMART SM00382 38 231 4.6E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 SUPERFAMILY SSF52540 13 241 2.25E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 PANTHER PTHR24220:SF520 15 265 1.4E-184 T 16-09-2016 Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 Gene3D G3DSA:3.40.50.300 11 250 1.7E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 Pfam PF00005 ABC transporter 29 183 8.4E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 PANTHER PTHR24220 15 265 1.4E-184 T 16-09-2016 Spa2297_RS26500 8b8fb70a401111f0247248aba3e5b65e 266 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS05320 b297eacee4530b4915550df99afa56be 258 SUPERFAMILY SSF51695 17 251 2.07E-62 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS05320 b297eacee4530b4915550df99afa56be 258 PANTHER PTHR23344:SF10 22 254 1.7E-69 T 16-09-2016 Spa2297_RS05320 b297eacee4530b4915550df99afa56be 258 PANTHER PTHR23344 22 254 1.7E-69 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS05320 b297eacee4530b4915550df99afa56be 258 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 23 246 1.5E-42 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS05320 b297eacee4530b4915550df99afa56be 258 Gene3D G3DSA:3.20.20.190 14 257 3.9E-76 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS22405 225ef8d20a41916d88f5d8f95ad8a7e8 146 Pfam PF08239 Bacterial SH3 domain 80 136 1.0E-7 T 16-09-2016 IPR003646 SH3-like domain, bacterial-type Spa2297_RS10490 163ff05a1b501a84129ceb136fe87353 116 SUPERFAMILY SSF50022 19 114 2.1E-29 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS10490 163ff05a1b501a84129ceb136fe87353 116 Pfam PF13806 Rieske-like [2Fe-2S] domain 20 114 6.0E-31 T 16-09-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 Spa2297_RS10490 163ff05a1b501a84129ceb136fe87353 116 PANTHER PTHR40562 12 113 1.5E-33 T 16-09-2016 Spa2297_RS10490 163ff05a1b501a84129ceb136fe87353 116 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 20 114 6.3E-25 T 16-09-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 Spa2297_RS10490 163ff05a1b501a84129ceb136fe87353 116 Gene3D G3DSA:2.102.10.10 18 114 4.0E-33 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.7E-42 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.7E-42 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 2.7E-42 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.7E-42 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.7E-42 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 Gene3D G3DSA:3.30.70.141 2 134 6.2E-56 T 16-09-2016 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 PANTHER PTHR11349 3 134 3.7E-66 T 16-09-2016 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 16-09-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 3.2E-52 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 32.941 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 SUPERFAMILY SSF54919 2 135 2.23E-52 T 16-09-2016 Spa2297_RS11040 3a062e3ce19f89b446ba12db121b559c 137 SMART SM00562 2 137 1.4E-76 T 16-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spa2297_RS16140 0f9d0fb1008d272e93f1157b0813b47e 275 PANTHER PTHR23344:SF28 4 273 1.7E-71 T 16-09-2016 Spa2297_RS16140 0f9d0fb1008d272e93f1157b0813b47e 275 PANTHER PTHR23344 4 273 1.7E-71 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS16140 0f9d0fb1008d272e93f1157b0813b47e 275 SUPERFAMILY SSF51695 8 272 1.33E-66 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS16140 0f9d0fb1008d272e93f1157b0813b47e 275 Gene3D G3DSA:3.20.20.190 4 273 3.3E-76 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS16140 0f9d0fb1008d272e93f1157b0813b47e 275 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 267 6.4E-45 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS29120 13766b2990048fd23aa17219fc819edd 413 PANTHER PTHR23513 1 404 7.5E-34 T 16-09-2016 Spa2297_RS29120 13766b2990048fd23aa17219fc819edd 413 SUPERFAMILY SSF103473 14 400 5.89E-32 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS29120 13766b2990048fd23aa17219fc819edd 413 Gene3D G3DSA:1.20.1250.20 14 193 6.1E-7 T 16-09-2016 Spa2297_RS29120 13766b2990048fd23aa17219fc819edd 413 Gene3D G3DSA:1.20.1250.20 227 397 2.7E-11 T 16-09-2016 Spa2297_RS29120 13766b2990048fd23aa17219fc819edd 413 Pfam PF07690 Major Facilitator Superfamily 20 326 8.5E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS15935 b09a233f8a568ff713507996a784fdc2 204 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 83 174 3.0E-15 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Gene3D G3DSA:3.40.50.10260 4 233 2.7E-58 T 16-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Pfam PF03853 YjeF-related protein N-terminus 25 194 2.3E-40 T 16-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 231 483 6.2E-46 T 16-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 17 215 3.9E-33 T 16-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Gene3D G3DSA:3.40.1190.20 234 484 1.4E-75 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 PANTHER PTHR12592 5 488 1.9E-96 T 16-09-2016 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 PIRSF PIRSF017184 3 487 1.6E-101 T 16-09-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 487 19.462 T 16-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 SUPERFAMILY SSF64153 5 248 9.29E-50 T 16-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Pfam PF01256 Carbohydrate kinase 250 476 7.8E-46 T 16-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 SUPERFAMILY SSF53613 227 484 3.07E-53 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 215 21.441 T 16-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spa2297_RS19990 1fcddbda75a17a7268a1007605e1e808 488 PANTHER PTHR12592:SF0 5 488 1.9E-96 T 16-09-2016 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 Pfam PF03840 Preprotein translocase SecG subunit 3 71 1.4E-19 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 PRINTS PR01651 Protein-export SecG membrane protein signature 21 35 3.1E-6 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 PRINTS PR01651 Protein-export SecG membrane protein signature 36 52 3.1E-6 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 PRINTS PR01651 Protein-export SecG membrane protein signature 52 74 3.1E-6 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 PRINTS PR01651 Protein-export SecG membrane protein signature 1 21 3.1E-6 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS07835 290eedf58b614260b1c37da7bc6aa665 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 4.9E-21 T 16-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 Pfam PF02687 FtsX-like permease family 310 422 7.4E-6 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 Pfam PF02687 FtsX-like permease family 976 1091 2.2E-10 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 PANTHER PTHR30489 733 1106 6.8E-136 T 16-09-2016 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 PANTHER PTHR30489 129 569 6.8E-136 T 16-09-2016 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 PANTHER PTHR30489:SF9 129 569 6.8E-136 T 16-09-2016 Spa2297_RS11330 80b0ba611e683bc73cdf58554f9836c8 1108 PANTHER PTHR30489:SF9 733 1106 6.8E-136 T 16-09-2016 Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 SUPERFAMILY SSF53822 55 360 1.09E-71 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 Gene3D G3DSA:3.40.50.2300 178 318 6.3E-35 T 16-09-2016 Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 PANTHER PTHR32196:SF1 42 327 2.6E-125 T 16-09-2016 IPR030159 Autoinducer 2-binding protein LsrB/rhamnose-binding protein RhaS GO:0043190 Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 Pfam PF13407 Periplasmic binding protein domain 59 317 4.3E-60 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 Gene3D G3DSA:3.40.50.2300 52 177 1.8E-30 T 16-09-2016 Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 59 359 8.6E-152 T 16-09-2016 IPR013459 Rhamnose-binding protein GO:0015762 Spa2297_RS29670 688db8205f609de928b69df9c999fec2 360 PANTHER PTHR32196 42 327 2.6E-125 T 16-09-2016 Spa2297_RS02950 8a0f8c1eea3cd33eea5a2cc4d17d4ad2 143 Gene3D G3DSA:3.40.630.30 5 115 6.0E-8 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02950 8a0f8c1eea3cd33eea5a2cc4d17d4ad2 143 SUPERFAMILY SSF55729 11 121 8.13E-8 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14840 f28bd6676cbdc15635083d77f0aba7dd 74 Pfam PF11662 Protein of unknown function (DUF3263) 3 74 5.9E-31 T 16-09-2016 IPR021678 Protein of unknown function DUF3263 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 Gene3D G3DSA:3.30.200.20 4 72 2.9E-17 T 16-09-2016 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 PANTHER PTHR24362:SF160 8 306 2.8E-72 T 16-09-2016 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 Gene3D G3DSA:1.10.510.10 73 262 1.6E-47 T 16-09-2016 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 SMART SM00220 9 273 4.6E-62 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 SUPERFAMILY SSF56112 6 264 4.05E-67 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 Pfam PF00069 Protein kinase domain 9 262 1.4E-45 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS12855 5304441f22bb2d88fb3893e9d09f7930 417 PANTHER PTHR24362 8 306 2.8E-72 T 16-09-2016 Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 PANTHER PTHR31151:SF4 47 772 4.0E-87 T 16-09-2016 Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 SUPERFAMILY SSF50370 664 798 3.92E-40 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 Gene3D G3DSA:2.80.10.50 666 798 3.8E-29 T 16-09-2016 Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 701 785 2.6E-21 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 99 538 2.1E-67 T 16-09-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 SMART SM00458 661 799 7.9E-6 T 16-09-2016 IPR000772 Ricin B, lectin domain Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 SUPERFAMILY SSF48208 88 360 9.35E-15 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS00250 d406d2a8301b9f3ce29283bb774ccc1e 799 PANTHER PTHR31151 47 772 4.0E-87 T 16-09-2016 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 125 141 6.6E-5 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 141 152 6.6E-5 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 152 171 6.6E-5 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Gene3D G3DSA:1.10.10.10 124 170 3.8E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Gene3D G3DSA:3.30.70.920 22 91 1.0E-12 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 SUPERFAMILY SSF46785 125 184 1.62E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 SUPERFAMILY SSF54909 17 93 9.12E-10 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 PANTHER PTHR30154 117 267 3.5E-19 T 16-09-2016 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 SUPERFAMILY SSF54909 184 264 6.03E-8 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Pfam PF13404 AsnC-type helix-turn-helix domain 126 165 6.2E-11 T 16-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 SMART SM00344 125 228 3.3E-4 T 16-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Pfam PF01037 Lrp/AsnC ligand binding domain 191 261 5.6E-6 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Pfam PF01037 Lrp/AsnC ligand binding domain 23 91 4.5E-11 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS34000 86e94e116987ca26d7fe3778e65f35c5 278 Gene3D G3DSA:3.30.70.920 179 265 2.3E-7 T 16-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 Gene3D G3DSA:3.20.20.140 202 489 4.2E-27 T 16-09-2016 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 PANTHER PTHR22642:SF2 2 544 7.8E-152 T 16-09-2016 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 PANTHER PTHR22642 2 544 7.8E-152 T 16-09-2016 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 Pfam PF07969 Amidohydrolase family 53 544 7.6E-93 T 16-09-2016 IPR013108 Amidohydrolase 3 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 SUPERFAMILY SSF51556 64 125 4.68E-31 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 SUPERFAMILY SSF51556 200 503 4.68E-31 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 Gene3D G3DSA:2.30.40.10 490 543 2.8E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 SUPERFAMILY SSF51338 503 545 7.68E-24 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 SUPERFAMILY SSF51338 6 65 7.68E-24 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS24985 9793d1d807d733b4ba59df6f725ecfa2 545 Gene3D G3DSA:2.30.40.10 6 110 6.3E-17 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF56784 309 368 5.94E-36 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF56784 413 601 5.94E-36 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 525 639 5.2E-27 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 86 332 1.1E-28 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Pfam PF00122 E1-E2 ATPase 84 304 4.6E-50 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF81665 20 115 1.44E-62 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF81665 600 796 1.44E-62 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF81665 213 307 1.44E-62 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Pfam PF00702 haloacid dehalogenase-like hydrolase 309 565 1.8E-17 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 315 321 - T 16-09-2016 IPR018303 P-type ATPase, phosphorylation site Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 SUPERFAMILY SSF81653 118 209 4.58E-20 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PANTHER PTHR24093:SF298 8 797 0.0 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Gene3D G3DSA:1.20.1110.10 520 787 2.7E-55 T 16-09-2016 IPR023298 P-type ATPase, transmembrane domain Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Gene3D G3DSA:1.20.1110.10 71 109 2.7E-55 T 16-09-2016 IPR023298 P-type ATPase, transmembrane domain Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PANTHER PTHR24093 8 797 0.0 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 475 485 1.9E-22 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 313 327 1.9E-22 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 1.9E-22 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 586 1.9E-22 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 570 1.9E-22 T 16-09-2016 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Gene3D G3DSA:3.40.1110.10 303 335 1.5E-5 T 16-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Gene3D G3DSA:2.70.150.10 110 210 2.5E-23 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 Gene3D G3DSA:2.70.150.10 21 58 2.5E-23 T 16-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 416 434 3.8E-7 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 551 567 3.8E-7 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS14630 17d6f84247746aeb1c727136536617cb 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 582 607 3.8E-7 T 16-09-2016 IPR001757 P-type ATPase GO:0016021 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Gene3D G3DSA:1.10.150.210 193 244 6.5E-25 T 16-09-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 1.2E-28 T 16-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 170 386 9.4E-77 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Gene3D G3DSA:3.30.70.260 113 182 3.0E-4 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Gene3D G3DSA:3.30.70.260 11 85 3.0E-14 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 PANTHER PTHR10000:SF7 177 392 5.8E-91 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 SUPERFAMILY SSF56784 182 389 7.2E-49 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 SUPERFAMILY SSF55021 12 83 2.26E-8 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 2.4E-23 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 PANTHER PTHR10000 177 392 5.8E-91 T 16-09-2016 Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Gene3D G3DSA:3.40.50.1000 245 373 7.4E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS07185 e9bb5d45ccbb26886cb3b1a64a0ee3bc 414 Pfam PF13740 ACT domain 11 84 1.4E-15 T 16-09-2016 Spa2297_RS14760 220d8871207d5245e988b8ab27613246 194 PANTHER PTHR30055 3 192 3.1E-73 T 16-09-2016 Spa2297_RS14760 220d8871207d5245e988b8ab27613246 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 3.0E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14760 220d8871207d5245e988b8ab27613246 194 Gene3D G3DSA:1.10.357.10 8 188 6.4E-29 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS14760 220d8871207d5245e988b8ab27613246 194 SUPERFAMILY SSF46689 3 68 6.16E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14760 220d8871207d5245e988b8ab27613246 194 PANTHER PTHR30055:SF91 3 192 3.1E-73 T 16-09-2016 Spa2297_RS18275 640681d24ad8eee864d0ab2af2ff58fe 417 PANTHER PTHR10289:SF7 92 373 1.7E-116 T 16-09-2016 Spa2297_RS18275 640681d24ad8eee864d0ab2af2ff58fe 417 SUPERFAMILY SSF53383 92 355 3.94E-60 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS18275 640681d24ad8eee864d0ab2af2ff58fe 417 PANTHER PTHR10289 92 373 1.7E-116 T 16-09-2016 Spa2297_RS18275 640681d24ad8eee864d0ab2af2ff58fe 417 Pfam PF01212 Beta-eliminating lyase 96 324 1.9E-25 T 16-09-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Spa2297_RS18275 640681d24ad8eee864d0ab2af2ff58fe 417 Gene3D G3DSA:3.40.640.10 97 290 2.0E-34 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 Pfam PF00665 Integrase core domain 122 244 6.0E-22 T 16-09-2016 IPR001584 Integrase, catalytic core GO:0015074 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 Gene3D G3DSA:1.10.10.60 6 39 7.8E-6 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 PANTHER PTHR24559 107 245 1.4E-18 T 16-09-2016 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 SUPERFAMILY SSF53098 116 291 5.94E-33 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 Pfam PF13565 Homeodomain-like domain 22 97 4.3E-17 T 16-09-2016 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 Gene3D G3DSA:3.30.420.10 116 281 6.4E-38 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS17380 1781f122197f623b072847895d9575d6 581 SUPERFAMILY SSF46689 3 101 1.65E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30915 dd2080475efc47ad6112507b08f0bf79 316 PANTHER PTHR32243 22 314 2.2E-100 T 16-09-2016 Spa2297_RS30915 dd2080475efc47ad6112507b08f0bf79 316 Gene3D G3DSA:1.10.3720.10 78 306 2.0E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30915 dd2080475efc47ad6112507b08f0bf79 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 296 4.0E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30915 dd2080475efc47ad6112507b08f0bf79 316 SUPERFAMILY SSF161098 72 292 7.98E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30915 dd2080475efc47ad6112507b08f0bf79 316 PANTHER PTHR32243:SF40 22 314 2.2E-100 T 16-09-2016 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 Pfam PF13520 Amino acid permease 21 424 2.0E-63 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PIRSF PIRSF006060 3 427 4.6E-49 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PANTHER PTHR11785:SF77 18 453 2.3E-183 T 16-09-2016 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PRINTS PR00173 Glutamate-aspartate symporter signature 458 477 3.2E-5 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PRINTS PR00173 Glutamate-aspartate symporter signature 17 37 3.2E-5 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PRINTS PR00173 Glutamate-aspartate symporter signature 98 123 3.2E-5 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 16 484 4.0E-148 T 16-09-2016 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 Spa2297_RS30600 13c54cfc03eab97e9797569749a96326 484 PANTHER PTHR11785 18 453 2.3E-183 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS19265 8299cf99f3cc3e120caf7dd82f8b97f9 199 PANTHER PTHR35400:SF1 1 199 3.5E-38 T 16-09-2016 Spa2297_RS19265 8299cf99f3cc3e120caf7dd82f8b97f9 199 SUPERFAMILY SSF52980 17 160 3.54E-15 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS19265 8299cf99f3cc3e120caf7dd82f8b97f9 199 Pfam PF05685 Putative restriction endonuclease 23 190 9.7E-21 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS19265 8299cf99f3cc3e120caf7dd82f8b97f9 199 PANTHER PTHR35400 1 199 3.5E-38 T 16-09-2016 Spa2297_RS19265 8299cf99f3cc3e120caf7dd82f8b97f9 199 Gene3D G3DSA:3.90.1570.10 16 156 1.1E-13 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 Gene3D G3DSA:3.90.1720.10 192 321 1.0E-36 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 Pfam PF00877 NlpC/P60 family 211 309 5.0E-22 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 SUPERFAMILY SSF53955 48 184 1.45E-32 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 Gene3D G3DSA:1.10.530.10 48 191 6.5E-33 T 16-09-2016 Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 PANTHER PTHR21666 141 322 2.8E-34 T 16-09-2016 Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 Pfam PF01464 Transglycosylase SLT domain 64 174 6.7E-15 T 16-09-2016 IPR008258 Transglycosylase SLT domain 1 Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 PANTHER PTHR21666:SF190 141 322 2.8E-34 T 16-09-2016 Spa2297_RS15515 befbfd9a4e41e89edbdc835936f2b0fb 332 SUPERFAMILY SSF54001 193 320 1.37E-33 T 16-09-2016 Spa2297_RS08510 c645ccb28ef96985ba793141f56f95fe 242 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 241 6.2E-46 T 16-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase Spa2297_RS08510 c645ccb28ef96985ba793141f56f95fe 242 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 240 9.7E-68 T 16-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase Spa2297_RS08510 c645ccb28ef96985ba793141f56f95fe 242 PANTHER PTHR30616 9 242 5.2E-85 T 16-09-2016 Spa2297_RS08510 c645ccb28ef96985ba793141f56f95fe 242 SUPERFAMILY SSF64438 8 242 2.2E-74 T 16-09-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spa2297_RS08510 c645ccb28ef96985ba793141f56f95fe 242 Gene3D G3DSA:3.60.140.10 8 241 5.4E-82 T 16-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 6.7E-8 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 6.7E-8 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 6.7E-8 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 PANTHER PTHR23501:SF48 10 469 4.3E-184 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 423 5.9E-91 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 PANTHER PTHR23501 10 469 4.3E-184 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 Gene3D G3DSA:1.20.1250.20 267 459 4.1E-24 T 16-09-2016 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 SUPERFAMILY SSF103473 18 207 5.93E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 SUPERFAMILY SSF103473 252 459 5.93E-65 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 Pfam PF07690 Major Facilitator Superfamily 24 413 5.8E-52 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS19580 ca52b58f39b4681a9a896bb010946b4c 493 Gene3D G3DSA:1.20.1250.20 18 190 1.2E-30 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 SUPERFAMILY SSF52540 4 227 2.12E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 PANTHER PTHR11669 43 226 1.4E-60 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 PANTHER PTHR11669 4 25 1.4E-60 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 Pfam PF13177 DNA polymerase III, delta subunit 41 188 2.5E-32 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 PANTHER PTHR11669:SF8 43 226 1.4E-60 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 PANTHER PTHR11669:SF8 4 25 1.4E-60 T 16-09-2016 Spa2297_RS18005 8028afc0f5d3b5233e1730108e13c1ce 401 Gene3D G3DSA:3.40.50.300 4 188 1.3E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10665 0d7bfda5fbe0efbe40eb7efb1c9bf5dc 333 Gene3D G3DSA:3.40.50.300 101 305 1.1E-103 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10665 0d7bfda5fbe0efbe40eb7efb1c9bf5dc 333 SUPERFAMILY SSF52540 95 280 9.55E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10665 0d7bfda5fbe0efbe40eb7efb1c9bf5dc 333 PANTHER PTHR30473 1 328 6.1E-173 T 16-09-2016 Spa2297_RS10665 0d7bfda5fbe0efbe40eb7efb1c9bf5dc 333 PANTHER PTHR30473:SF1 1 328 6.1E-173 T 16-09-2016 Spa2297_RS10665 0d7bfda5fbe0efbe40eb7efb1c9bf5dc 333 Pfam PF02562 PhoH-like protein 102 305 1.4E-95 T 16-09-2016 IPR003714 PhoH-like protein GO:0005524 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1160 1174 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1226 1265 4.0E-10 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 825 864 7.4E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 734 773 1.4E-10 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 962 1001 8.9E-6 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1091 1127 0.0069 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1274 1311 65.0 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 780 819 3.6E-4 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 916 955 5.4E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 688 727 1.4E-7 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1134 1173 6.9E-11 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1041 1079 2.1 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 870 909 6.2E-10 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1002 1034 100.0 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SMART SM00320 1179 1219 3.7E-8 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 714 728 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1021 1035 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Gene3D G3DSA:3.40.50.300 148 197 1.5E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SUPERFAMILY SSF101908 1017 1315 5.23E-59 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Gene3D G3DSA:2.120.10.30 945 1009 6.5E-12 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1114 1128 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847 704 1063 2.3E-157 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847 368 397 2.3E-157 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847 1111 1316 2.3E-157 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 1188 1218 7.0E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 830 864 1.9E-7 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 797 819 0.0014 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 875 909 1.8E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 978 1001 0.0041 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 1104 1127 0.038 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 922 955 4.0E-7 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 739 773 9.2E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 1229 1265 4.8E-6 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 695 727 5.8E-5 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Pfam PF00400 WD domain, G-beta repeat 1140 1173 6.9E-9 T 16-09-2016 IPR001680 WD40 repeat GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 942 956 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SUPERFAMILY SSF50998 1121 1223 6.51E-83 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SUPERFAMILY SSF50998 700 1008 6.51E-83 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 896 910 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PRINTS PR00320 G protein beta WD-40 repeat signature 760 774 2.6E-9 T 16-09-2016 IPR020472 G-protein beta WD-40 repeat Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PRINTS PR00320 G protein beta WD-40 repeat signature 1160 1174 2.6E-9 T 16-09-2016 IPR020472 G-protein beta WD-40 repeat Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PRINTS PR00320 G protein beta WD-40 repeat signature 896 910 2.6E-9 T 16-09-2016 IPR020472 G-protein beta WD-40 repeat Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SUPERFAMILY SSF52540 151 239 1.46E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 SUPERFAMILY SSF52540 293 399 1.46E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 760 774 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Gene3D G3DSA:2.130.10.10 1013 1312 8.1E-69 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 Gene3D G3DSA:2.130.10.10 692 944 2.6E-83 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1252 1266 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 806 820 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 851 865 - T 16-09-2016 IPR019775 WD40 repeat, conserved site Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847:SF50 704 1063 2.3E-157 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847:SF50 368 397 2.3E-157 T 16-09-2016 Spa2297_RS16615 39756f77e87741f1e8cca02d53fd0660 1349 PANTHER PTHR22847:SF50 1111 1316 2.3E-157 T 16-09-2016 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 PANTHER PTHR11748:SF78 6 448 5.1E-170 T 16-09-2016 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 Gene3D G3DSA:3.30.43.10 4 88 1.4E-25 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 Pfam PF01565 FAD binding domain 33 171 4.6E-40 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 SUPERFAMILY SSF56176 2 209 5.61E-70 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 Gene3D G3DSA:1.10.45.10 408 447 7.9E-15 T 16-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 PANTHER PTHR11748 6 448 5.1E-170 T 16-09-2016 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 Gene3D G3DSA:3.30.465.10 89 209 2.9E-43 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 Pfam PF02913 FAD linked oxidases, C-terminal domain 209 447 3.7E-67 T 16-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Spa2297_RS12520 8b41e79a5aa590698b6109440efbfecc 448 SUPERFAMILY SSF55103 184 447 3.11E-62 T 16-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PANTHER PTHR24319:SF23 1 246 1.9E-56 T 16-09-2016 Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PANTHER PTHR24319 1 246 1.9E-56 T 16-09-2016 Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.1E-19 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 9.1E-19 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 9.1E-19 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 9.1E-19 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 SUPERFAMILY SSF51735 1 247 3.06E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.1E-44 T 16-09-2016 Spa2297_RS07305 62491d12f910229254572ec95eb2afd1 251 Gene3D G3DSA:3.40.50.720 1 247 3.2E-62 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29380 a45e55378159114a8ca10852789dbac4 224 Pfam PF00293 NUDIX domain 73 191 1.6E-9 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS29380 a45e55378159114a8ca10852789dbac4 224 SUPERFAMILY SSF55811 38 216 8.67E-44 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS29380 a45e55378159114a8ca10852789dbac4 224 PANTHER PTHR11839 41 216 1.4E-37 T 16-09-2016 Spa2297_RS29380 a45e55378159114a8ca10852789dbac4 224 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 51 212 1.3E-39 T 16-09-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Spa2297_RS29380 a45e55378159114a8ca10852789dbac4 224 Gene3D G3DSA:3.90.79.10 36 215 1.7E-51 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS05090 2c3fa30e38373a2c756873c96c728ed9 278 Pfam PF05949 Bacterial protein of unknown function (DUF881) 118 261 1.5E-37 T 16-09-2016 IPR010273 Protein of unknown function DUF881 Spa2297_RS05090 2c3fa30e38373a2c756873c96c728ed9 278 PANTHER PTHR37313 1 274 3.8E-153 T 16-09-2016 Spa2297_RS05090 2c3fa30e38373a2c756873c96c728ed9 278 PANTHER PTHR37313:SF1 1 274 3.8E-153 T 16-09-2016 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 SUPERFAMILY SSF53790 1 240 7.07E-49 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 SUPERFAMILY SSF53790 250 482 1.27E-50 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 PANTHER PTHR21091 1 180 4.3E-41 T 16-09-2016 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 253 459 3.2E-36 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 1.8E-50 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 253 495 2.7E-81 T 16-09-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 Gene3D G3DSA:3.40.1010.10 251 364 1.4E-27 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 Gene3D G3DSA:3.40.1010.10 1 134 3.9E-36 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 PANTHER PTHR21091:SF127 1 180 4.3E-41 T 16-09-2016 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 Gene3D G3DSA:3.30.950.10 365 475 3.5E-12 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 16-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS00590 9261168601d19d365bc37d26ca6b2cae 498 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 234 1.2E-65 T 16-09-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 Spa2297_RS14095 f9af4ee4060aa30f4f6afd9ff064d361 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 85 5.2E-11 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS14095 f9af4ee4060aa30f4f6afd9ff064d361 143 SUPERFAMILY SSF54593 5 117 2.28E-19 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14095 f9af4ee4060aa30f4f6afd9ff064d361 143 Gene3D G3DSA:3.10.180.10 6 116 1.9E-23 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS14095 f9af4ee4060aa30f4f6afd9ff064d361 143 PANTHER PTHR41294:SF1 2 139 1.1E-59 T 16-09-2016 Spa2297_RS14095 f9af4ee4060aa30f4f6afd9ff064d361 143 PANTHER PTHR41294 2 139 1.1E-59 T 16-09-2016 Spa2297_RS29450 311f3dd09722be3fd2a702c818404ca8 216 Gene3D G3DSA:2.80.10.50 104 213 1.2E-9 T 16-09-2016 Spa2297_RS29450 311f3dd09722be3fd2a702c818404ca8 216 SUPERFAMILY SSF50405 72 211 1.94E-11 T 16-09-2016 IPR008999 Actin cross-linking Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 SUPERFAMILY SSF53738 300 432 6.67E-27 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 146 155 - T 16-09-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 SUPERFAMILY SSF53738 35 213 7.06E-41 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Gene3D G3DSA:3.30.310.50 457 534 6.9E-21 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 SUPERFAMILY SSF53738 208 312 3.22E-20 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 PANTHER PTHR22573:SF54 24 541 5.5E-207 T 16-09-2016 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 426 7.9E-17 T 16-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Gene3D G3DSA:3.40.120.10 306 435 1.1E-33 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 222 312 7.5E-23 T 16-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 PANTHER PTHR22573 24 541 5.5E-207 T 16-09-2016 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 SUPERFAMILY SSF55957 434 534 2.35E-16 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 45 187 8.3E-39 T 16-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Gene3D G3DSA:3.40.120.10 227 305 2.0E-20 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 452 515 2.8E-10 T 16-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS20810 4236921eeb12fe13c23ebf9230cf27a7 548 Gene3D G3DSA:3.40.120.10 19 213 4.1E-59 T 16-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 SUPERFAMILY SSF46955 18 100 7.78E-11 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 SMART SM00422 18 86 1.1E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 PANTHER PTHR30204:SF29 10 101 4.2E-33 T 16-09-2016 Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 Gene3D G3DSA:1.10.1660.10 18 95 2.1E-12 T 16-09-2016 Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 Pfam PF13411 MerR HTH family regulatory protein 18 81 4.4E-9 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS19760 8101db8d5797a0334d92e4de67bea3b8 118 PANTHER PTHR30204 10 101 4.2E-33 T 16-09-2016 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 PIRSF PIRSF002134 1 125 2.8E-42 T 16-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.599 T 16-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 Gene3D G3DSA:1.10.8.50 1 72 7.1E-31 T 16-09-2016 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 16-09-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 PANTHER PTHR10871 1 122 1.7E-69 T 16-09-2016 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.0E-31 T 16-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.7E-50 T 16-09-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 SUPERFAMILY SSF46946 2 122 3.27E-44 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS19920 f0b0b493e73f7f24e837ac5f4fed51a5 126 Gene3D G3DSA:4.10.910.10 73 124 5.6E-25 T 16-09-2016 IPR027437 30s ribosomal protein S13, C-terminal Spa2297_RS26140 fc1dc4a4e170fa456abd04a785f41d36 122 PANTHER PTHR33823 1 122 1.4E-53 T 16-09-2016 Spa2297_RS26140 fc1dc4a4e170fa456abd04a785f41d36 122 SUPERFAMILY SSF57716 87 120 7.13E-5 T 16-09-2016 Spa2297_RS26140 fc1dc4a4e170fa456abd04a785f41d36 122 PANTHER PTHR33823:SF1 1 122 1.4E-53 T 16-09-2016 Spa2297_RS27590 a222f478040d19c6f432252a57373f68 343 SUPERFAMILY SSF53474 62 339 1.66E-42 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27590 a222f478040d19c6f432252a57373f68 343 PANTHER PTHR10907 50 210 7.3E-40 T 16-09-2016 Spa2297_RS27590 a222f478040d19c6f432252a57373f68 343 PANTHER PTHR10907:SF33 50 210 7.3E-40 T 16-09-2016 Spa2297_RS27590 a222f478040d19c6f432252a57373f68 343 Pfam PF00756 Putative esterase 70 333 2.0E-32 T 16-09-2016 IPR000801 Putative esterase Spa2297_RS27590 a222f478040d19c6f432252a57373f68 343 Gene3D G3DSA:3.40.50.1820 59 340 1.9E-73 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS27055 f30421d1690a8b613658a95a97bc847c 309 PANTHER PTHR10459 116 267 2.7E-39 T 16-09-2016 Spa2297_RS27055 f30421d1690a8b613658a95a97bc847c 309 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 264 1.6E-72 T 16-09-2016 IPR014145 DNA ligase D, polymerase domain Spa2297_RS27055 f30421d1690a8b613658a95a97bc847c 309 PANTHER PTHR10459:SF44 116 267 2.7E-39 T 16-09-2016 Spa2297_RS27055 f30421d1690a8b613658a95a97bc847c 309 Pfam PF01896 DNA primase small subunit 140 260 1.1E-7 T 16-09-2016 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 SUPERFAMILY SSF51621 18 915 3.14E-272 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 133 144 - T 16-09-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 9 915 18.287 T 16-09-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PANTHER PTHR30523:SF0 14 915 0.0 T 16-09-2016 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 181 197 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 394 414 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 558 578 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 737 763 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 132 145 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 600 629 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 239 254 4.5E-58 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 Pfam PF00311 Phosphoenolpyruvate carboxylase 128 915 1.5E-286 T 16-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 PANTHER PTHR30523 14 915 0.0 T 16-09-2016 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 560 572 - T 16-09-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Spa2297_RS13575 62ac6aa2b7cedc5549c3c8798c8c343e 915 Gene3D G3DSA:1.20.1440.90 274 396 3.8E-23 T 16-09-2016 Spa2297_RS17450 e0a9b99da49c3082bcccc43a91e4c3a6 165 PANTHER PTHR22573 18 149 1.2E-17 T 16-09-2016 Spa2297_RS17450 e0a9b99da49c3082bcccc43a91e4c3a6 165 PANTHER PTHR22573:SF51 18 149 1.2E-17 T 16-09-2016 Spa2297_RS17450 e0a9b99da49c3082bcccc43a91e4c3a6 165 Pfam PF00156 Phosphoribosyl transferase domain 13 151 9.1E-22 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS17450 e0a9b99da49c3082bcccc43a91e4c3a6 165 Gene3D G3DSA:3.40.50.2020 9 153 2.6E-32 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS17450 e0a9b99da49c3082bcccc43a91e4c3a6 165 SUPERFAMILY SSF53271 8 151 2.83E-26 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 SUPERFAMILY SSF51905 157 324 3.56E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 Pfam PF00743 Flavin-binding monooxygenase-like 2 430 6.6E-81 T 16-09-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 Gene3D G3DSA:3.50.50.60 322 413 6.8E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 Gene3D G3DSA:3.50.50.60 2 153 6.8E-58 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PANTHER PTHR23023:SF55 1 432 3.3E-174 T 16-09-2016 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PIRSF PIRSF000332 1 434 8.5E-87 T 16-09-2016 IPR012143 Dimethylaniline monooxygenase, N-oxide-forming GO:0004499|GO:0050660|GO:0050661|GO:0055114 KEGG: 00982+1.14.13.8 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 354 371 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 168 182 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 137 153 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 308 335 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 25 49 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 1 15 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 371 384 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 75 90 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 100 112 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 195 210 2.3E-42 T 16-09-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 PANTHER PTHR23023 1 432 3.3E-174 T 16-09-2016 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 Gene3D G3DSA:3.50.50.60 158 220 1.7E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 Gene3D G3DSA:3.50.50.60 289 321 1.7E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS01395 a6741eaf720757a9f04cd153299b2a8a 436 SUPERFAMILY SSF51905 2 213 2.75E-47 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS21710 fd1fa727429b0768f798b67a73fa2f4c 332 Pfam PF13490 Putative zinc-finger 19 47 1.3E-8 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS27695 fbdc217d5a84ce95aba5ac31c63a96d6 311 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 1.0E-77 T 16-09-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA Spa2297_RS27695 fbdc217d5a84ce95aba5ac31c63a96d6 311 PANTHER PTHR38658 1 311 8.5E-101 T 16-09-2016 Spa2297_RS27695 fbdc217d5a84ce95aba5ac31c63a96d6 311 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 311 3.0E-121 T 16-09-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA Spa2297_RS27695 fbdc217d5a84ce95aba5ac31c63a96d6 311 PANTHER PTHR38658:SF1 1 311 8.5E-101 T 16-09-2016 Spa2297_RS18905 520851681e0356d192e2faf51b9be8b7 210 Pfam PF13649 Methyltransferase domain 49 139 7.2E-19 T 16-09-2016 Spa2297_RS18905 520851681e0356d192e2faf51b9be8b7 210 SUPERFAMILY SSF53335 6 196 9.22E-37 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS18905 520851681e0356d192e2faf51b9be8b7 210 Gene3D G3DSA:3.40.50.150 5 188 3.8E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS18905 520851681e0356d192e2faf51b9be8b7 210 PANTHER PTHR10108 33 188 6.7E-23 T 16-09-2016 Spa2297_RS20750 54550c024eb9ff50f86caa25223fb704 67 PANTHER PTHR33885 1 67 2.6E-22 T 16-09-2016 Spa2297_RS20750 54550c024eb9ff50f86caa25223fb704 67 Pfam PF04024 PspC domain 3 58 2.7E-17 T 16-09-2016 IPR007168 Phage shock protein, PspC, N-terminal Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 PANTHER PTHR22916:SF29 110 529 1.5E-208 T 16-09-2016 Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 PANTHER PTHR22916:SF29 1 74 1.5E-208 T 16-09-2016 Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 SUPERFAMILY SSF53448 116 262 1.03E-30 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 SUPERFAMILY SSF53448 1 77 1.03E-30 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 Pfam PF13641 Glycosyltransferase like family 2 18 259 4.8E-16 T 16-09-2016 Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 PANTHER PTHR22916 1 74 1.5E-208 T 16-09-2016 Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 PANTHER PTHR22916 110 529 1.5E-208 T 16-09-2016 Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 Gene3D G3DSA:3.90.550.10 1 81 2.5E-28 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13130 c24fc27a136d4a3c8789d23fe842ffb0 1234 Gene3D G3DSA:3.90.550.10 117 259 2.5E-28 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 Gene3D G3DSA:3.40.50.300 18 250 2.7E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 PANTHER PTHR24220 20 276 5.8E-144 T 16-09-2016 Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 SMART SM00382 43 231 9.7E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 PANTHER PTHR24220:SF266 20 276 5.8E-144 T 16-09-2016 Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 Pfam PF00005 ABC transporter 35 182 1.0E-30 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 SUPERFAMILY SSF52540 14 244 1.6E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31080 cb6e3a49c91b04265437b5ba114ab3f5 287 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS06340 9541e05fbfae592f64d44fc204258977 317 Pfam PF13280 WYL domain 148 314 7.2E-33 T 16-09-2016 IPR026881 WYL domain Spa2297_RS06340 9541e05fbfae592f64d44fc204258977 317 PANTHER PTHR34580 1 316 4.7E-80 T 16-09-2016 Spa2297_RS06340 9541e05fbfae592f64d44fc204258977 317 PANTHER PTHR34580:SF3 1 316 4.7E-80 T 16-09-2016 Spa2297_RS28605 770047a04a59371ba74ddc85f32599f5 265 Gene3D G3DSA:3.40.630.40 3 263 1.3E-60 T 16-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 Spa2297_RS28605 770047a04a59371ba74ddc85f32599f5 265 Pfam PF05013 N-formylglutamate amidohydrolase 17 238 2.4E-47 T 16-09-2016 IPR007709 N-formylglutamate amidohydrolase Spa2297_RS28605 770047a04a59371ba74ddc85f32599f5 265 SUPERFAMILY SSF53187 6 264 1.16E-54 T 16-09-2016 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 178 6.6E-12 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 SUPERFAMILY SSF88659 127 179 2.4E-6 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 Gene3D G3DSA:1.10.10.10 131 179 3.9E-6 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 Pfam PF04542 Sigma-70 region 2 33 98 4.0E-10 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 PANTHER PTHR30173:SF31 4 178 3.7E-50 T 16-09-2016 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 SUPERFAMILY SSF88946 17 98 4.71E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 Pfam PF08281 Sigma-70, region 4 131 177 2.1E-6 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 PANTHER PTHR30173 4 178 3.7E-50 T 16-09-2016 Spa2297_RS14400 5b92e693531a7469b41d7ec020b19d25 201 Gene3D G3DSA:1.10.1740.10 15 99 7.1E-13 T 16-09-2016 Spa2297_RS16920 2214a501752de57417fb8a46aebf9491 263 PANTHER PTHR23088 1 255 2.4E-84 T 16-09-2016 Spa2297_RS16920 2214a501752de57417fb8a46aebf9491 263 SUPERFAMILY SSF56317 1 255 2.35E-73 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS16920 2214a501752de57417fb8a46aebf9491 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 16-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site Spa2297_RS16920 2214a501752de57417fb8a46aebf9491 263 Pfam PF00795 Carbon-nitrogen hydrolase 3 246 4.1E-51 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS16920 2214a501752de57417fb8a46aebf9491 263 Gene3D G3DSA:3.60.110.10 1 255 6.6E-79 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS07110 584dfd2ecde1c622e4ca548651ceaba4 260 Pfam PF07070 SpoOM protein 3 216 4.2E-80 T 16-09-2016 IPR009776 Sporulation stage 0, protein M Spa2297_RS07110 584dfd2ecde1c622e4ca548651ceaba4 260 PANTHER PTHR40053 1 260 5.9E-110 T 16-09-2016 Spa2297_RS02485 aca87961676de1ecbca3018e816b7161 286 PANTHER PTHR36151 5 286 5.1E-96 T 16-09-2016 Spa2297_RS02485 aca87961676de1ecbca3018e816b7161 286 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 20 247 3.2E-52 T 16-09-2016 IPR018713 Domain of unknown function DUF2236 Spa2297_RS02485 aca87961676de1ecbca3018e816b7161 286 PANTHER PTHR36151:SF3 5 286 5.1E-96 T 16-09-2016 Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 PANTHER PTHR30522:SF0 1 324 2.9E-96 T 16-09-2016 IPR011551 NTP pyrophosphohydrolase MazG Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 SUPERFAMILY SSF101386 130 225 4.91E-23 T 16-09-2016 Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 149 223 3.6E-28 T 16-09-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 Gene3D G3DSA:1.10.287.1080 130 199 2.3E-12 T 16-09-2016 Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 PANTHER PTHR30522 1 324 2.9E-96 T 16-09-2016 Spa2297_RS13465 f8556008d6e3f1c87a953c7f871f42f9 325 SUPERFAMILY SSF53790 27 103 7.12E-6 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 PANTHER PTHR10245:SF29 1 283 2.8E-140 T 16-09-2016 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 PANTHER PTHR10245 1 283 2.8E-140 T 16-09-2016 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 Gene3D G3DSA:1.10.260.40 7 73 6.8E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 SMART SM00530 17 72 1.9E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 Pfam PF13560 Helix-turn-helix domain 13 76 3.4E-10 T 16-09-2016 Spa2297_RS19120 5f138a60202b64ff988003daba27a4b6 283 SUPERFAMILY SSF47413 10 73 4.79E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS30385 041711138dc67dab2e500d9e1bd50d30 97 PANTHER PTHR40137:SF1 2 97 6.5E-61 T 16-09-2016 Spa2297_RS30385 041711138dc67dab2e500d9e1bd50d30 97 Pfam PF05121 Gas vesicle protein K 9 92 4.9E-36 T 16-09-2016 IPR007805 Gas vesicle protein GvpK GO:0031412 Spa2297_RS30385 041711138dc67dab2e500d9e1bd50d30 97 PANTHER PTHR40137 2 97 6.5E-61 T 16-09-2016 Spa2297_RS13530 f3ff16345f52370efd253deb59dd1b73 290 Gene3D G3DSA:3.40.1580.10 121 154 3.9E-6 T 16-09-2016 IPR018958 SMI1/KNR4-like domain Spa2297_RS13530 f3ff16345f52370efd253deb59dd1b73 290 SUPERFAMILY SSF160631 115 232 1.01E-14 T 16-09-2016 Spa2297_RS13530 f3ff16345f52370efd253deb59dd1b73 290 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 58 93 3.4E-13 T 16-09-2016 IPR032869 WHH domain-containing protein Spa2297_RS13530 f3ff16345f52370efd253deb59dd1b73 290 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 123 231 9.2E-8 T 16-09-2016 IPR018958 SMI1/KNR4-like domain Spa2297_RS13530 f3ff16345f52370efd253deb59dd1b73 290 SMART SM00860 122 260 0.002 T 16-09-2016 IPR018958 SMI1/KNR4-like domain Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 PANTHER PTHR31571 35 284 6.9E-67 T 16-09-2016 Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 PANTHER PTHR31571:SF1 35 284 6.9E-67 T 16-09-2016 Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 240 275 2.8E-10 T 16-09-2016 Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 SUPERFAMILY SSF51695 205 277 1.19E-14 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 SUPERFAMILY SSF51695 43 166 1.19E-14 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS04310 24d186d188a8ccb3bd0cec3b9fd95a1c 287 Gene3D G3DSA:3.20.20.190 58 285 3.7E-9 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS19490 0095fa438b289d22c3d566b975bdf50e 522 PANTHER PTHR22773 25 516 2.5E-110 T 16-09-2016 Spa2297_RS19490 0095fa438b289d22c3d566b975bdf50e 522 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 31 514 14.882 T 16-09-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Spa2297_RS19490 0095fa438b289d22c3d566b975bdf50e 522 Pfam PF00361 Proton-conducting membrane transporter 158 463 3.3E-51 T 16-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 Spa2297_RS19490 0095fa438b289d22c3d566b975bdf50e 522 PANTHER PTHR22773:SF41 25 516 2.5E-110 T 16-09-2016 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 SMART SM00895 113 234 3.0E-16 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 2.5E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 2.5E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 Pfam PF07729 FCD domain 113 232 1.1E-17 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 SMART SM00345 29 90 5.9E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 90 1.4E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 Gene3D G3DSA:1.10.10.10 26 94 1.4E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 SUPERFAMILY SSF48008 110 242 3.92E-21 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 Gene3D G3DSA:1.20.120.530 110 240 6.8E-20 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 PANTHER PTHR11751 27 129 9.0E-20 T 16-09-2016 Spa2297_RS06225 25e2602301905ae8d36773ca9cdf1b66 244 SUPERFAMILY SSF46785 21 94 6.04E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 Pfam PF00149 Calcineurin-like phosphoesterase 13 201 9.5E-15 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 PANTHER PTHR12905 4 238 3.8E-62 T 16-09-2016 Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 11 258 33.865 T 16-09-2016 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 SUPERFAMILY SSF56300 13 257 3.04E-43 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 Gene3D G3DSA:3.60.21.10 12 221 2.4E-28 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS25620 3a63a895816908c764f4b64f039f7e29 259 PANTHER PTHR12905:SF7 4 238 3.8E-62 T 16-09-2016 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 SUPERFAMILY SSF103473 30 458 1.44E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 PANTHER PTHR23508 32 468 7.6E-261 T 16-09-2016 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 ProSitePatterns PS00217 Sugar transport proteins signature 2. 154 179 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 Gene3D G3DSA:1.20.1250.20 43 244 1.9E-25 T 16-09-2016 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 Gene3D G3DSA:1.20.1250.20 269 454 6.7E-23 T 16-09-2016 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 Pfam PF07690 Major Facilitator Superfamily 79 391 4.6E-33 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09760 d1d108d37e34866522ddaed1ff88a8b6 468 PANTHER PTHR23508:SF17 32 468 7.6E-261 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 SUPERFAMILY SSF56801 29 536 3.53E-133 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Gene3D G3DSA:3.40.50.980 57 208 1.5E-30 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Gene3D G3DSA:3.30.300.30 439 534 8.3E-34 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Gene3D G3DSA:3.40.50.980 209 357 3.0E-34 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 528 1.4E-25 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Gene3D G3DSA:2.30.38.10 363 435 2.6E-13 T 16-09-2016 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 Pfam PF00501 AMP-binding enzyme 55 444 1.7E-78 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS25150 71a3478897974d959f353b5910569953 540 PANTHER PTHR24095 42 534 2.2E-137 T 16-09-2016 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 SUPERFAMILY SSF48056 3 287 9.16E-58 T 16-09-2016 IPR008922 Uncharacterised domain, di-copper centre Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 219 230 - T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 PANTHER PTHR11474 7 249 9.4E-58 T 16-09-2016 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 55 72 - T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 55 72 3.8E-17 T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 199 210 3.8E-17 T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 84 89 3.8E-17 T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 PRINTS PR00092 Tyrosinase copper-binding domain signature 218 236 3.8E-17 T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 Gene3D G3DSA:1.10.1280.10 3 259 6.5E-54 T 16-09-2016 IPR008922 Uncharacterised domain, di-copper centre Spa2297_RS11415 8332849ab3bfc3ac2870b5f938f8d2fd 288 Pfam PF00264 Common central domain of tyrosinase 30 238 2.5E-39 T 16-09-2016 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Spa2297_RS05405 5fa13ade792732f8ab47f2eb2f03edef 155 Pfam PF10756 Bacterial PH domain 69 139 1.4E-18 T 16-09-2016 IPR019692 Protein of unknown function DUF2581 Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 PANTHER PTHR35525 5 186 6.7E-78 T 16-09-2016 Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 SUPERFAMILY SSF160904 2 180 9.68E-49 T 16-09-2016 Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 Pfam PF11706 CGNR zinc finger 138 181 4.5E-18 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 PANTHER PTHR35525:SF1 5 186 6.7E-78 T 16-09-2016 Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 Pfam PF07336 Putative stress-induced transcription regulator 13 128 6.6E-14 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS05860 f3322259bb020d848f072cfec828e0b0 186 Gene3D G3DSA:1.10.3300.10 3 183 4.9E-54 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS00325 b414f4b585e256c3121495468647a206 1058 SUPERFAMILY SSF74650 563 1011 7.85E-29 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS00325 b414f4b585e256c3121495468647a206 1058 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 569 820 7.0E-16 T 16-09-2016 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 Spa2297_RS00325 b414f4b585e256c3121495468647a206 1058 Gene3D G3DSA:3.20.110.10 126 316 4.5E-10 T 16-09-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain Spa2297_RS00325 b414f4b585e256c3121495468647a206 1058 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 132 431 3.1E-15 T 16-09-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 Spa2297_RS00325 b414f4b585e256c3121495468647a206 1058 SUPERFAMILY SSF88713 124 334 6.67E-28 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS24475 af75d8ae95c530178ced8483daf3d717 161 PANTHER PTHR30445 5 161 6.3E-50 T 16-09-2016 Spa2297_RS24475 af75d8ae95c530178ced8483daf3d717 161 Gene3D G3DSA:3.30.70.1450 86 159 4.3E-19 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24475 af75d8ae95c530178ced8483daf3d717 161 PIRSF PIRSF005028 2 161 3.3E-54 T 16-09-2016 IPR026278 Potassium/proton antiporter subunit KhtT Spa2297_RS24475 af75d8ae95c530178ced8483daf3d717 161 Pfam PF02080 TrkA-C domain 90 159 1.0E-12 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24475 af75d8ae95c530178ced8483daf3d717 161 SUPERFAMILY SSF116726 82 159 3.14E-16 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS25140 135d025f21525b637ab71b656a7262d4 296 Pfam PF13469 Sulfotransferase family 61 239 9.5E-27 T 16-09-2016 Spa2297_RS25140 135d025f21525b637ab71b656a7262d4 296 SUPERFAMILY SSF52540 59 249 2.1E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25140 135d025f21525b637ab71b656a7262d4 296 Gene3D G3DSA:3.40.50.300 59 244 1.0E-17 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 Pfam PF01547 Bacterial extracellular solute-binding protein 63 351 2.1E-32 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 Gene3D G3DSA:3.40.190.10 22 157 1.6E-22 T 16-09-2016 Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 Gene3D G3DSA:3.40.190.10 165 359 2.5E-21 T 16-09-2016 Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 PANTHER PTHR30061 1 444 5.4E-68 T 16-09-2016 Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 PANTHER PTHR30061:SF1 1 444 5.4E-68 T 16-09-2016 Spa2297_RS31440 44d67ffef2331a792fd94d6f14384b22 445 SUPERFAMILY SSF53850 46 444 1.26E-58 T 16-09-2016 Spa2297_RS19055 d4144af46d1c83dbabb0ec1ed16d409d 161 Pfam PF07811 TadE-like protein 35 77 8.0E-13 T 16-09-2016 IPR012495 TadE-like Spa2297_RS03650 a7b4996beddf5c71094cf183269c88bd 130 SUPERFAMILY SSF54593 9 121 6.85E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03650 a7b4996beddf5c71094cf183269c88bd 130 Gene3D G3DSA:3.10.180.10 9 123 8.3E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS03650 a7b4996beddf5c71094cf183269c88bd 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 3.0E-12 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PANTHER PTHR24322 152 181 8.9E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PANTHER PTHR24322 6 136 8.9E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 Pfam PF00106 short chain dehydrogenase 3 192 1.2E-36 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.4E-22 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.4E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.4E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.4E-5 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 SUPERFAMILY SSF51735 2 213 1.38E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 Gene3D G3DSA:3.40.50.720 3 196 1.3E-51 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07160 1250db5b3ef74f770c57507ce3cf758f 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS24990 5928b8b101299243f904024fc407dcec 443 Gene3D G3DSA:1.20.1250.20 27 197 1.8E-14 T 16-09-2016 Spa2297_RS24990 5928b8b101299243f904024fc407dcec 443 Gene3D G3DSA:1.20.1250.20 243 424 5.2E-8 T 16-09-2016 Spa2297_RS24990 5928b8b101299243f904024fc407dcec 443 PANTHER PTHR23513 7 420 2.0E-43 T 16-09-2016 Spa2297_RS24990 5928b8b101299243f904024fc407dcec 443 SUPERFAMILY SSF103473 26 420 1.96E-34 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS24990 5928b8b101299243f904024fc407dcec 443 Pfam PF07690 Major Facilitator Superfamily 30 375 2.9E-29 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 3.1E-8 T 16-09-2016 IPR010663 Zinc finger, FPG/IleRS-type Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 104 1.7E-15 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 SMART SM01232 137 229 8.2E-31 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 SUPERFAMILY SSF81624 2 142 9.29E-26 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 Gene3D G3DSA:3.20.190.10 2 137 6.5E-21 T 16-09-2016 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 Gene3D G3DSA:1.10.8.50 138 272 5.5E-37 T 16-09-2016 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 SUPERFAMILY SSF57716 233 272 4.28E-11 T 16-09-2016 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 SUPERFAMILY SSF46946 136 219 3.93E-25 T 16-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 SMART SM00898 2 123 4.2E-25 T 16-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 PANTHER PTHR22993 1 272 2.1E-183 T 16-09-2016 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 137 222 1.1E-20 T 16-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Spa2297_RS28930 64470e156a199324677c6d9723bf173a 287 PANTHER PTHR22993:SF16 1 272 2.1E-183 T 16-09-2016 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 Gene3D G3DSA:1.10.10.10 134 196 3.8E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 SUPERFAMILY SSF88946 38 118 5.65E-24 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 195 8.9E-33 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 PANTHER PTHR30173 38 200 1.3E-69 T 16-09-2016 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 SUPERFAMILY SSF88659 134 195 3.92E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 Pfam PF04542 Sigma-70 region 2 42 107 1.1E-20 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 Gene3D G3DSA:1.10.1740.10 36 108 3.0E-26 T 16-09-2016 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 Pfam PF08281 Sigma-70, region 4 140 191 1.1E-16 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS21705 667e838be75594cdfdda8819f50b06d9 223 PANTHER PTHR30173:SF18 38 200 1.3E-69 T 16-09-2016 Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 PANTHER PTHR12001:SF45 141 373 3.9E-108 T 16-09-2016 Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 PANTHER PTHR12001:SF45 1 124 3.9E-108 T 16-09-2016 Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 PANTHER PTHR12001 141 373 3.9E-108 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 105 119 - T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 Gene3D G3DSA:1.10.600.10 23 366 4.0E-71 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 Pfam PF00348 Polyprenyl synthetase 59 295 1.3E-44 T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 SUPERFAMILY SSF48576 34 352 4.86E-64 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS00750 d091514793daa1453d351cb32e5652f6 381 PANTHER PTHR12001 1 124 3.9E-108 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS14660 07fa13174ecc3ca451405279ca0a100e 282 PANTHER PTHR37167 4 282 2.8E-109 T 16-09-2016 Spa2297_RS14660 07fa13174ecc3ca451405279ca0a100e 282 Gene3D G3DSA:3.40.190.10 80 181 2.3E-15 T 16-09-2016 Spa2297_RS14660 07fa13174ecc3ca451405279ca0a100e 282 Pfam PF02621 Menaquinone biosynthesis 6 266 3.5E-91 T 16-09-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 Spa2297_RS14660 07fa13174ecc3ca451405279ca0a100e 282 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 5 272 41.725 T 16-09-2016 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 UniPathway: UPA00079 Spa2297_RS14660 07fa13174ecc3ca451405279ca0a100e 282 SUPERFAMILY SSF53850 6 271 1.09E-84 T 16-09-2016 Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 393 2.1E-136 T 16-09-2016 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 PANTHER PTHR30094 5 394 2.0E-82 T 16-09-2016 Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 PANTHER PTHR30094:SF0 5 394 2.0E-82 T 16-09-2016 Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 SUPERFAMILY SSF52440 178 292 3.74E-34 T 16-09-2016 IPR016185 Pre-ATP-grasp domain Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 SUPERFAMILY SSF56059 3 169 5.65E-70 T 16-09-2016 Spa2297_RS20415 1792c40ced907310f42676528b15172e 394 SUPERFAMILY SSF56059 279 392 5.65E-70 T 16-09-2016 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 1.5E-118 T 16-09-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 SUPERFAMILY SSF52374 4 310 2.48E-88 T 16-09-2016 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 Gene3D G3DSA:3.40.50.620 21 303 7.3E-96 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 4.3E-27 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.3E-27 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 4.3E-27 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.3E-27 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 SUPERFAMILY SSF47323 330 463 2.22E-30 T 16-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 Gene3D G3DSA:1.20.120.640 304 393 8.1E-20 T 16-09-2016 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 PANTHER PTHR10890 3 463 2.9E-203 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 SMART SM00840 341 403 9.2E-15 T 16-09-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.222 T 16-09-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 1.1E-138 T 16-09-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 Spa2297_RS15075 6dd1fd614013dbc81d44c864a766642a 466 Pfam PF09190 DALR domain 341 394 1.1E-10 T 16-09-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 Pfam PF13416 Bacterial extracellular solute-binding protein 66 371 1.3E-24 T 16-09-2016 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 SUPERFAMILY SSF53850 46 439 2.99E-48 T 16-09-2016 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 Gene3D G3DSA:3.40.190.10 178 367 1.5E-25 T 16-09-2016 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 PANTHER PTHR30061 1 441 7.9E-258 T 16-09-2016 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 Gene3D G3DSA:3.40.190.10 97 177 3.2E-7 T 16-09-2016 Spa2297_RS11855 69117c702a4fd92b5f41cf6fa355aac4 441 PANTHER PTHR30061:SF28 1 441 7.9E-258 T 16-09-2016 Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 SMART SM00849 26 220 3.1E-16 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 PANTHER PTHR11935:SF28 1 239 1.0E-21 T 16-09-2016 Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 Gene3D G3DSA:3.60.15.10 8 239 1.5E-44 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 Pfam PF00753 Metallo-beta-lactamase superfamily 26 220 3.2E-16 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 PANTHER PTHR11935 1 239 1.0E-21 T 16-09-2016 Spa2297_RS10765 c0f6363bd35e043bd70cc44cb9dfc5f8 244 SUPERFAMILY SSF56281 6 238 3.22E-36 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS15380 19a7b1ec0d6c33e773aff184d1e996b2 84 SUPERFAMILY SSF54285 4 84 2.43E-14 T 16-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Spa2297_RS15380 19a7b1ec0d6c33e773aff184d1e996b2 84 Gene3D G3DSA:3.10.20.30 3 84 9.7E-15 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS15380 19a7b1ec0d6c33e773aff184d1e996b2 84 Pfam PF02597 ThiS family 6 84 3.1E-9 T 16-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Spa2297_RS15380 19a7b1ec0d6c33e773aff184d1e996b2 84 PANTHER PTHR33359 1 84 1.1E-20 T 16-09-2016 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 PANTHER PTHR11699 13 463 1.1E-205 T 16-09-2016 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 Gene3D G3DSA:3.40.309.10 251 435 4.0E-59 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 237 244 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 265 276 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 Gene3D G3DSA:3.40.605.10 13 250 6.7E-73 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 SUPERFAMILY SSF53720 12 456 2.62E-137 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 Pfam PF00171 Aldehyde dehydrogenase family 14 452 3.2E-134 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS31885 0c9fbd574a47c01591014a5529f0553f 467 PANTHER PTHR11699:SF164 13 463 1.1E-205 T 16-09-2016 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 PIRSF PIRSF006487 1 372 2.2E-99 T 16-09-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Gene3D G3DSA:3.30.70.1400 57 144 5.3E-29 T 16-09-2016 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 261 5.9E-93 T 16-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 370 2.2E-105 T 16-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Hamap MF_00259 Aminomethyltransferase [gcvT]. 5 370 45.132 T 16-09-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 364 2.9E-22 T 16-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 SUPERFAMILY SSF101790 284 371 2.45E-24 T 16-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 SUPERFAMILY SSF103025 6 279 1.29E-97 T 16-09-2016 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 PANTHER PTHR13847:SF5 1 367 2.6E-51 T 16-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 PANTHER PTHR13847 1 367 2.6E-51 T 16-09-2016 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Gene3D G3DSA:3.30.1360.120 145 239 8.8E-54 T 16-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Gene3D G3DSA:3.30.1360.120 7 56 8.8E-54 T 16-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spa2297_RS23135 dabc242d947b6a7a960ed3f00e241f82 372 Gene3D G3DSA:2.40.30.110 289 372 1.4E-28 T 16-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spa2297_RS28495 cb21bf3f3a4e34e8868b757d470726aa 300 PANTHER PTHR12110 10 298 2.9E-102 T 16-09-2016 Spa2297_RS28495 cb21bf3f3a4e34e8868b757d470726aa 300 PANTHER PTHR12110:SF3 10 298 2.9E-102 T 16-09-2016 Spa2297_RS28495 cb21bf3f3a4e34e8868b757d470726aa 300 Pfam PF01261 Xylose isomerase-like TIM barrel 34 246 5.4E-30 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS28495 cb21bf3f3a4e34e8868b757d470726aa 300 Gene3D G3DSA:3.20.20.150 5 299 5.2E-68 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS28495 cb21bf3f3a4e34e8868b757d470726aa 300 SUPERFAMILY SSF51658 5 294 2.21E-51 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137:SF2 153 370 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137:SF2 129 137 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 Gene3D G3DSA:3.20.20.30 157 370 2.0E-96 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 Gene3D G3DSA:3.20.20.30 5 116 2.0E-96 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137 1 113 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 Pfam PF00296 Luciferase-like monooxygenase 183 343 4.0E-9 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 Pfam PF00296 Luciferase-like monooxygenase 6 122 2.1E-24 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137 153 370 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137 129 137 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 PANTHER PTHR30137:SF2 1 113 3.1E-78 T 16-09-2016 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 SUPERFAMILY SSF51679 157 370 1.51E-66 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28795 26aae731c7a948b43f0d6ef241a02dd5 375 SUPERFAMILY SSF51679 4 116 1.51E-66 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 PANTHER PTHR11814 10 478 1.1E-259 T 16-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 Pfam PF00916 Sulfate permease family 166 357 1.8E-27 T 16-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 Pfam PF00916 Sulfate permease family 17 141 8.2E-21 T 16-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 SUPERFAMILY SSF52091 398 476 8.24E-13 T 16-09-2016 IPR002645 STAS domain Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 Gene3D G3DSA:3.30.750.24 401 474 2.4E-9 T 16-09-2016 IPR002645 STAS domain Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 PANTHER PTHR11814:SF76 10 478 1.1E-259 T 16-09-2016 Spa2297_RS18745 812a0b6d6ce39c8a142938f864d3b6e8 490 Pfam PF01740 STAS domain 398 474 2.0E-8 T 16-09-2016 IPR002645 STAS domain Spa2297_RS05340 eb3adef0fa3c37de869fceb167e7ba70 285 Gene3D G3DSA:3.90.550.10 23 235 1.5E-24 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS05340 eb3adef0fa3c37de869fceb167e7ba70 285 PANTHER PTHR10859 5 248 8.7E-69 T 16-09-2016 Spa2297_RS05340 eb3adef0fa3c37de869fceb167e7ba70 285 SUPERFAMILY SSF53448 22 235 5.63E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS05340 eb3adef0fa3c37de869fceb167e7ba70 285 Pfam PF00535 Glycosyl transferase family 2 25 187 9.2E-27 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 SUPERFAMILY SSF50475 11 142 8.79E-35 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 PANTHER PTHR35176 1 144 9.0E-74 T 16-09-2016 Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 PANTHER PTHR35176:SF2 1 144 9.0E-74 T 16-09-2016 Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 140 1.6E-42 T 16-09-2016 IPR019920 F420-binding domain, putative Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 Gene3D G3DSA:2.30.110.10 11 141 1.3E-28 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS22445 c283495bd52352bfca3def0a0faeae7a 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 88 2.8E-15 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS06600 02c88891682e84c6e22bc940e91899fb 341 PANTHER PTHR21310 9 247 9.6E-20 T 16-09-2016 Spa2297_RS06600 02c88891682e84c6e22bc940e91899fb 341 SUPERFAMILY SSF56112 7 314 7.89E-62 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS06600 02c88891682e84c6e22bc940e91899fb 341 Pfam PF01636 Phosphotransferase enzyme family 33 289 3.9E-51 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS06600 02c88891682e84c6e22bc940e91899fb 341 Gene3D G3DSA:3.90.1200.10 126 315 3.2E-34 T 16-09-2016 Spa2297_RS06600 02c88891682e84c6e22bc940e91899fb 341 PANTHER PTHR21310:SF14 9 247 9.6E-20 T 16-09-2016 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 PANTHER PTHR11070 86 354 9.9E-261 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 PANTHER PTHR11070:SF25 392 679 9.9E-261 T 16-09-2016 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 Gene3D G3DSA:3.40.50.300 379 516 1.1E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 Gene3D G3DSA:3.40.50.300 182 244 1.1E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 Gene3D G3DSA:3.40.50.300 519 686 7.1E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 PANTHER PTHR11070:SF25 86 354 9.9E-261 T 16-09-2016 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 PANTHER PTHR11070 392 679 9.9E-261 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 Pfam PF13245 Part of AAA domain 191 254 2.1E-13 T 16-09-2016 Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 SUPERFAMILY SSF52540 175 254 3.39E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 SUPERFAMILY SSF52540 357 388 3.39E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14705 bc7318c189a04ada00d4dc4d436cc9a4 688 SUPERFAMILY SSF52540 439 681 3.39E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.8E-15 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 3.8E-15 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 3.8E-15 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 3.8E-15 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 1.8E-8 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.8E-8 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-8 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PANTHER PTHR22912:SF180 2 280 3.0E-24 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 290 1.3E-39 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 Gene3D G3DSA:3.50.50.60 112 310 1.0E-28 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 SUPERFAMILY SSF51905 1 328 3.84E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 PANTHER PTHR22912 2 280 3.0E-24 T 16-09-2016 Spa2297_RS17265 09a54f885e4e11c327f72e2be0a5c629 396 Gene3D G3DSA:3.50.50.60 2 111 4.7E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PANTHER PTHR11958 14 468 2.3E-162 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 1.2E-20 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 1.2E-20 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PRINTS PR00173 Glutamate-aspartate symporter signature 85 110 1.2E-20 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 1.2E-20 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 Gene3D G3DSA:1.10.3860.10 15 418 6.2E-104 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 307 330 - T 16-09-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 SUPERFAMILY SSF118215 20 414 1.83E-108 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 Pfam PF00375 Sodium:dicarboxylate symporter family 20 413 2.5E-107 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS00485 e3389631dbd2e487a2e33a02632e0496 479 PANTHER PTHR11958:SF49 14 468 2.3E-162 T 16-09-2016 Spa2297_RS23995 541cb8f41b65e49c6eb616a60ca0ad19 443 Pfam PF01474 Class-II DAHP synthetase family 14 437 7.6E-179 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS23995 541cb8f41b65e49c6eb616a60ca0ad19 443 SUPERFAMILY SSF51569 14 441 4.91E-178 T 16-09-2016 Spa2297_RS23995 541cb8f41b65e49c6eb616a60ca0ad19 443 PANTHER PTHR21337 15 443 3.8E-232 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS23995 541cb8f41b65e49c6eb616a60ca0ad19 443 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 14 442 3.9E-198 T 16-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 SUPERFAMILY SSF161098 272 528 1.96E-46 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 252 1.0E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 343 519 1.7E-9 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 PANTHER PTHR30183 1 532 7.3E-237 T 16-09-2016 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 Gene3D G3DSA:1.10.3720.10 277 528 2.2E-46 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 Gene3D G3DSA:1.10.3720.10 4 254 4.7E-45 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 PANTHER PTHR30183:SF8 1 532 7.3E-237 T 16-09-2016 Spa2297_RS23855 a75d1d0836c177c4f45f867ccf0bf6ce 533 SUPERFAMILY SSF161098 4 248 2.62E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 5.0E-7 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.0E-7 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 5.0E-7 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 1.4E-54 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 SUPERFAMILY SSF51905 1 302 7.13E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 Gene3D G3DSA:3.50.50.60 2 95 5.6E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PANTHER PTHR22912:SF1 1 377 2.0E-109 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 5.2E-21 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 5.2E-21 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-21 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 92 110 5.2E-21 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 5.2E-21 T 16-09-2016 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 Gene3D G3DSA:3.50.50.60 96 302 1.2E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS10480 11442f9133bc24f8cef29dc2f0a23636 410 PANTHER PTHR22912 1 377 2.0E-109 T 16-09-2016 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 SMART SM00382 532 716 1.1E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 SUPERFAMILY SSF52540 500 738 3.45E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 SUPERFAMILY SSF90123 186 483 3.14E-44 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Gene3D G3DSA:3.40.50.300 505 734 2.4E-69 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Gene3D G3DSA:3.90.70.10 37 160 4.0E-18 T 16-09-2016 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Pfam PF00664 ABC transporter transmembrane region 191 457 3.9E-24 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 PANTHER PTHR24221 110 739 2.4E-259 T 16-09-2016 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Pfam PF03412 Peptidase C39 family 30 162 9.3E-38 T 16-09-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Pfam PF00005 ABC transporter 524 672 8.6E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 TIGRFAM TIGR03796 NHLM_micro_ABC1: NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein 29 738 0.0 T 16-09-2016 IPR022514 NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 PANTHER PTHR24221:SF161 110 739 2.4E-259 T 16-09-2016 Spa2297_RS29935 4299707ae7a6ca762b64a57cc8049214 740 Gene3D G3DSA:1.20.1560.10 183 481 7.2E-45 T 16-09-2016 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 317 4.9E-23 T 16-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 SUPERFAMILY SSF51735 4 174 2.16E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 340 38.107 T 16-09-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 Gene3D G3DSA:3.40.50.720 2 158 1.0E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 SUPERFAMILY SSF55347 150 314 7.63E-48 T 16-09-2016 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 PANTHER PTHR32338 3 346 9.6E-151 T 16-09-2016 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 346 3.1E-116 T 16-09-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 SMART SM00859 4 140 9.6E-43 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 Gene3D G3DSA:3.30.360.10 159 314 2.7E-57 T 16-09-2016 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 16-09-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 133 2.1E-23 T 16-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spa2297_RS06085 777297580bd9c17acc4fd3d70f7ad891 346 PANTHER PTHR32338:SF8 3 346 9.6E-151 T 16-09-2016 Spa2297_RS15460 7b96bcf14a90a966e09bd643102782b8 144 PANTHER PTHR21340 9 134 4.4E-28 T 16-09-2016 Spa2297_RS15460 7b96bcf14a90a966e09bd643102782b8 144 SUPERFAMILY SSF55811 7 137 9.61E-26 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS15460 7b96bcf14a90a966e09bd643102782b8 144 Pfam PF00293 NUDIX domain 8 129 2.3E-15 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS15460 7b96bcf14a90a966e09bd643102782b8 144 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS15460 7b96bcf14a90a966e09bd643102782b8 144 Gene3D G3DSA:3.90.79.10 6 133 5.0E-27 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS12305 8bb892721721d19c72a45e390922e155 117 PANTHER PTHR36221 3 116 1.2E-16 T 16-09-2016 Spa2297_RS12305 8bb892721721d19c72a45e390922e155 117 Pfam PF05331 Protein of unknown function (DUF742) 6 115 1.4E-31 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS12305 8bb892721721d19c72a45e390922e155 117 SUPERFAMILY SSF46785 47 91 2.04E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12305 8bb892721721d19c72a45e390922e155 117 Gene3D G3DSA:1.10.10.10 49 91 1.3E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 Gene3D G3DSA:3.40.640.10 42 293 1.2E-87 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 PANTHER PTHR11601:SF17 11 417 8.0E-198 T 16-09-2016 Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 Gene3D G3DSA:3.90.1150.10 294 412 5.0E-29 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 SUPERFAMILY SSF53383 9 413 1.09E-126 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 PANTHER PTHR11601 11 417 8.0E-198 T 16-09-2016 Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 Pfam PF00266 Aminotransferase class-V 31 406 2.0E-153 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS07735 1bf2374770eb4ea72125326f06837e3f 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 418 4.4E-186 T 16-09-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 Spa2297_RS23245 bda43bc5bd66b1ce5f7bb92e3bd10195 336 SUPERFAMILY SSF51726 52 332 9.42E-33 T 16-09-2016 Spa2297_RS23245 bda43bc5bd66b1ce5f7bb92e3bd10195 336 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 329 8.8E-10 T 16-09-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 Spa2297_RS23245 bda43bc5bd66b1ce5f7bb92e3bd10195 336 Gene3D G3DSA:3.20.20.210 81 333 5.3E-16 T 16-09-2016 Spa2297_RS03085 022ce8e438700cf60a966f53b009e19f 194 PANTHER PTHR42305 1 194 1.7E-54 T 16-09-2016 Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 SMART SM00829 10 322 4.2E-11 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 Pfam PF00107 Zinc-binding dehydrogenase 157 276 1.4E-18 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 SUPERFAMILY SSF51735 118 272 7.52E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 Gene3D G3DSA:3.40.50.720 150 265 7.6E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 3.1E-8 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 PANTHER PTHR11695:SF509 15 325 5.1E-80 T 16-09-2016 Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 Gene3D G3DSA:3.90.180.10 1 149 8.1E-32 T 16-09-2016 IPR011032 GroES-like Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 SUPERFAMILY SSF50129 1 151 2.13E-31 T 16-09-2016 IPR011032 GroES-like Spa2297_RS29460 65a233da7c97db7030e10bfa45492ea9 325 PANTHER PTHR11695 15 325 5.1E-80 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 17 240 1.7E-79 T 16-09-2016 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Gene3D G3DSA:3.30.1330.100 17 63 1.4E-56 T 16-09-2016 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Gene3D G3DSA:3.30.1330.100 130 220 1.4E-56 T 16-09-2016 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 21 442 53.584 T 16-09-2016 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 249 442 1.7E-98 T 16-09-2016 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 SUPERFAMILY SSF144010 18 245 1.23E-69 T 16-09-2016 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Pfam PF01996 F420-0:Gamma-glutamyl ligase 93 215 9.1E-34 T 16-09-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Pfam PF01996 F420-0:Gamma-glutamyl ligase 24 80 1.3E-9 T 16-09-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 SUPERFAMILY SSF55469 247 439 1.7E-39 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Gene3D G3DSA:3.40.109.10 244 440 1.9E-40 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Gene3D G3DSA:3.90.1660.10 69 129 1.5E-23 T 16-09-2016 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 PANTHER PTHR21712 14 234 7.2E-54 T 16-09-2016 Spa2297_RS13150 18227dda7840899836b4e96fce7e3441 442 Pfam PF00881 Nitroreductase family 252 422 1.9E-28 T 16-09-2016 IPR029479 Nitroreductase Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 Pfam PF01471 Putative peptidoglycan binding domain 97 152 2.1E-13 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 SUPERFAMILY SSF141523 182 294 6.02E-21 T 16-09-2016 Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 Gene3D G3DSA:2.40.440.10 183 295 2.4E-17 T 16-09-2016 Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 SUPERFAMILY SSF47090 83 159 9.1E-17 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 Gene3D G3DSA:1.10.101.10 91 157 5.4E-15 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS20570 c492ff75879f3231ce8af1e7e26f008b 296 Pfam PF03734 L,D-transpeptidase catalytic domain 183 294 1.5E-16 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 Gene3D G3DSA:1.20.1560.10 21 333 6.4E-45 T 16-09-2016 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 Pfam PF00664 ABC transporter transmembrane region 44 301 2.1E-19 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 PANTHER PTHR24221:SF161 467 599 1.3E-142 T 16-09-2016 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 PANTHER PTHR24221:SF161 5 432 1.3E-142 T 16-09-2016 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 SUPERFAMILY SSF52540 461 593 4.98E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 PANTHER PTHR24221 467 599 1.3E-142 T 16-09-2016 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 PANTHER PTHR24221 5 432 1.3E-142 T 16-09-2016 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 Gene3D G3DSA:3.40.50.300 462 598 5.0E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 Pfam PF00005 ABC transporter 396 526 6.5E-8 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23045 354207329ad681392019bd2335e103f0 602 SUPERFAMILY SSF90123 19 332 7.59E-52 T 16-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 Spa2297_RS03390 5b7b7ade22587a2bc28efd2b2c500feb 431 Gene3D G3DSA:2.60.60.30 12 164 6.3E-31 T 16-09-2016 Spa2297_RS03390 5b7b7ade22587a2bc28efd2b2c500feb 431 PIRSF PIRSF037118 1 431 3.7E-174 T 16-09-2016 IPR017115 Tellurite resistance, TerA Spa2297_RS03390 5b7b7ade22587a2bc28efd2b2c500feb 431 PANTHER PTHR32097 1 424 4.5E-151 T 16-09-2016 Spa2297_RS03390 5b7b7ade22587a2bc28efd2b2c500feb 431 Pfam PF02342 TerD domain 1 166 2.1E-40 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS03390 5b7b7ade22587a2bc28efd2b2c500feb 431 PANTHER PTHR32097:SF4 1 424 4.5E-151 T 16-09-2016 Spa2297_RS00955 f25ce99a9e4bbc6a4ea233499623e821 285 Pfam PF00722 Glycosyl hydrolases family 16 73 269 5.2E-43 T 16-09-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spa2297_RS00955 f25ce99a9e4bbc6a4ea233499623e821 285 Gene3D G3DSA:2.60.120.200 34 282 1.7E-78 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS00955 f25ce99a9e4bbc6a4ea233499623e821 285 PANTHER PTHR10963 43 282 5.1E-69 T 16-09-2016 Spa2297_RS00955 f25ce99a9e4bbc6a4ea233499623e821 285 SUPERFAMILY SSF49899 33 282 8.04E-73 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS22645 07c0501a157cbcd4decfd1bd97243052 215 PANTHER PTHR17490 1 210 3.2E-64 T 16-09-2016 Spa2297_RS22645 07c0501a157cbcd4decfd1bd97243052 215 Gene3D G3DSA:3.90.870.10 8 205 9.6E-64 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS22645 07c0501a157cbcd4decfd1bd97243052 215 SUPERFAMILY SSF55821 4 210 5.19E-56 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS22645 07c0501a157cbcd4decfd1bd97243052 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 7.8E-56 T 16-09-2016 IPR006070 YrdC-like domain GO:0003725 Spa2297_RS22645 07c0501a157cbcd4decfd1bd97243052 215 Pfam PF01300 Telomere recombination 23 197 3.6E-46 T 16-09-2016 IPR006070 YrdC-like domain GO:0003725 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 SUPERFAMILY SSF143800 2 76 1.18E-25 T 16-09-2016 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 19.072 T 16-09-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 Pfam PF00830 Ribosomal L28 family 4 60 5.2E-23 T 16-09-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 58 4.6E-25 T 16-09-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 PANTHER PTHR13528 2 74 1.5E-25 T 16-09-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 Spa2297_RS18065 36c4ed58a18ca158518862a2d5f32c50 78 Gene3D G3DSA:2.30.170.40 2 76 2.7E-30 T 16-09-2016 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 146 158 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 Gene3D G3DSA:1.10.510.10 93 276 2.5E-43 T 16-09-2016 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 Pfam PF00069 Protein kinase domain 23 269 2.5E-44 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 SUPERFAMILY SSF56112 14 283 1.25E-63 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 SMART SM00220 23 281 8.7E-54 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 Gene3D G3DSA:3.30.200.20 16 92 2.0E-22 T 16-09-2016 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 PANTHER PTHR24362:SF247 17 407 1.6E-79 T 16-09-2016 Spa2297_RS20140 579739467a96eae7b4df13a96b442cda 674 PANTHER PTHR24362 17 407 1.6E-79 T 16-09-2016 Spa2297_RS19495 3ab7068cd0e43bd78fb0719743a76495 287 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.863 T 16-09-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 Spa2297_RS19495 3ab7068cd0e43bd78fb0719743a76495 287 PANTHER PTHR10120 5 287 1.9E-101 T 16-09-2016 Spa2297_RS19495 3ab7068cd0e43bd78fb0719743a76495 287 PANTHER PTHR10120:SF19 5 287 1.9E-101 T 16-09-2016 Spa2297_RS19495 3ab7068cd0e43bd78fb0719743a76495 287 Pfam PF01435 Peptidase family M48 69 282 7.5E-35 T 16-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spa2297_RS19495 3ab7068cd0e43bd78fb0719743a76495 287 Gene3D G3DSA:3.30.2010.10 59 149 1.1E-30 T 16-09-2016 Spa2297_RS24540 35a01a9370d56aa4a8e61673fd9daff5 402 SUPERFAMILY SSF50494 152 378 8.96E-18 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS24540 35a01a9370d56aa4a8e61673fd9daff5 402 Gene3D G3DSA:2.40.10.10 169 227 8.7E-8 T 16-09-2016 Spa2297_RS14060 c6438d249d7ca470682fe24c64db4dcf 87 SUPERFAMILY SSF57850 7 87 3.06E-25 T 16-09-2016 Spa2297_RS14060 c6438d249d7ca470682fe24c64db4dcf 87 PANTHER PTHR24007 22 82 2.2E-16 T 16-09-2016 Spa2297_RS14060 c6438d249d7ca470682fe24c64db4dcf 87 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 23 86 7.7E-12 T 16-09-2016 IPR001607 Zinc finger, UBP-type GO:0008270 Spa2297_RS14060 c6438d249d7ca470682fe24c64db4dcf 87 Gene3D G3DSA:3.30.40.10 7 87 1.8E-22 T 16-09-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type Spa2297_RS29095 b51c9e9720fb03fe7f6b7cea5a4e76ae 154 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 49 148 1.4E-11 T 16-09-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 Spa2297_RS29095 b51c9e9720fb03fe7f6b7cea5a4e76ae 154 SUPERFAMILY SSF50118 45 148 2.83E-9 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS29095 b51c9e9720fb03fe7f6b7cea5a4e76ae 154 Gene3D G3DSA:2.30.30.110 47 148 2.2E-4 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 Gene3D G3DSA:2.60.40.1120 3 83 1.9E-12 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 Gene3D G3DSA:2.40.128.110 93 262 7.5E-53 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 Pfam PF04264 YceI-like domain 94 259 3.7E-38 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 PANTHER PTHR34406:SF1 39 264 1.2E-63 T 16-09-2016 Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 Pfam PF13620 Carboxypeptidase regulatory-like domain 3 81 3.0E-11 T 16-09-2016 Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 PANTHER PTHR34406 39 264 1.2E-63 T 16-09-2016 Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 SUPERFAMILY SSF49464 5 85 3.41E-10 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 SMART SM00867 93 261 1.8E-55 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS10815 2883f0febe9eb401706566bdca6748d8 264 SUPERFAMILY SSF101874 92 263 7.19E-48 T 16-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Spa2297_RS10530 fd59f22baace2db401c69c4b986d04d9 538 SUPERFAMILY SSF53649 434 470 3.05E-10 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS10530 fd59f22baace2db401c69c4b986d04d9 538 SUPERFAMILY SSF53649 256 406 3.05E-10 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS10530 fd59f22baace2db401c69c4b986d04d9 538 Gene3D G3DSA:3.40.720.10 255 471 4.4E-6 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 Hamap MF_00813 Probable allantoicase [alc]. 27 360 50.69 T 16-09-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 SUPERFAMILY SSF49785 30 210 8.33E-54 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 PIRSF PIRSF016516 25 361 7.6E-93 T 16-09-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 SUPERFAMILY SSF49785 215 360 6.46E-41 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 Pfam PF03561 Allantoicase repeat 229 357 7.2E-33 T 16-09-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 Pfam PF03561 Allantoicase repeat 47 206 3.5E-46 T 16-09-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 Gene3D G3DSA:2.60.120.260 216 361 5.6E-40 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 Gene3D G3DSA:2.60.120.260 32 210 2.6E-58 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 PANTHER PTHR12045 2 370 1.1E-134 T 16-09-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS26440 4dfbe03d3a735ee231d54f8653b5e363 376 TIGRFAM TIGR02961 allantoicase: allantoicase 38 357 6.0E-125 T 16-09-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 Spa2297_RS14620 ed6cc6b524de14e0295cf45746faa815 485 PANTHER PTHR11119:SF9 26 469 1.6E-124 T 16-09-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 Spa2297_RS14620 ed6cc6b524de14e0295cf45746faa815 485 PANTHER PTHR11119 26 469 1.6E-124 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS14620 ed6cc6b524de14e0295cf45746faa815 485 Pfam PF00860 Permease family 43 441 1.7E-26 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 Pfam PF01145 SPFH domain / Band 7 family 25 194 3.2E-35 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PANTHER PTHR10264:SF27 4 287 4.8E-118 T 16-09-2016 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 SMART SM00244 21 179 1.7E-52 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PANTHER PTHR10264 4 287 4.8E-118 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 SUPERFAMILY SSF117892 52 186 1.96E-39 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 76 97 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 111 128 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 174 195 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 28 50 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 131 154 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 PRINTS PR00721 Stomatin signature 155 173 1.6E-31 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS07125 f1f2eb0a1e9a7b0cf9927a823fc729cc 314 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 16-09-2016 IPR018080 Band 7/stomatin-like, conserved site Spa2297_RS11240 3c2aacadd0806e532f1d08ee913c6df6 178 SMART SM00507 70 119 2.4E-13 T 16-09-2016 IPR003615 HNH nuclease Spa2297_RS11240 3c2aacadd0806e532f1d08ee913c6df6 178 Pfam PF14279 HNH endonuclease 83 125 1.2E-12 T 16-09-2016 IPR029471 HNH endonuclease 5 Spa2297_RS11240 3c2aacadd0806e532f1d08ee913c6df6 178 PANTHER PTHR33877 3 169 8.5E-62 T 16-09-2016 Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 Gene3D G3DSA:3.40.630.30 12 108 1.0E-11 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 PANTHER PTHR23091 99 268 2.2E-40 T 16-09-2016 Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 Pfam PF00583 Acetyltransferase (GNAT) family 188 263 6.1E-11 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 Pfam PF00583 Acetyltransferase (GNAT) family 42 105 4.5E-6 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 SUPERFAMILY SSF55729 12 114 2.06E-12 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 Gene3D G3DSA:3.40.630.30 129 265 2.4E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 PANTHER PTHR23091:SF71 99 268 2.2E-40 T 16-09-2016 Spa2297_RS05880 dabb4b58ee3a12ddf8f926c9a176991a 274 SUPERFAMILY SSF55729 129 266 3.95E-23 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 SUPERFAMILY SSF53800 19 243 4.8E-36 T 16-09-2016 Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 Pfam PF01903 CbiX 26 122 2.1E-17 T 16-09-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 Pfam PF01903 CbiX 146 236 3.1E-10 T 16-09-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 Gene3D G3DSA:3.40.50.1400 20 130 9.2E-24 T 16-09-2016 Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 Gene3D G3DSA:3.40.50.1400 138 244 1.2E-19 T 16-09-2016 Spa2297_RS10430 95e05e84e419c3202b2bdd99ccd82511 260 PANTHER PTHR33542 14 246 3.5E-55 T 16-09-2016 Spa2297_RS29040 dbc6885a9af90a0d51b04291ade660f0 319 Pfam PF05239 PRC-barrel domain 6 75 1.7E-10 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS29040 dbc6885a9af90a0d51b04291ade660f0 319 Pfam PF09557 Domain of unknown function (DUF2382) 191 302 2.5E-28 T 16-09-2016 IPR019060 Domain of unknown function DUF2382 Spa2297_RS29040 dbc6885a9af90a0d51b04291ade660f0 319 SUPERFAMILY SSF50346 8 105 2.55E-17 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS00995 92182dfbefc75605a7d3d8004d37d04d 256 PANTHER PTHR35005 1 248 1.6E-51 T 16-09-2016 Spa2297_RS00995 92182dfbefc75605a7d3d8004d37d04d 256 PANTHER PTHR35005:SF1 1 248 1.6E-51 T 16-09-2016 Spa2297_RS00995 92182dfbefc75605a7d3d8004d37d04d 256 SUPERFAMILY SSF102215 5 248 3.27E-50 T 16-09-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 Spa2297_RS00995 92182dfbefc75605a7d3d8004d37d04d 256 Pfam PF02633 Creatinine amidohydrolase 8 245 1.2E-52 T 16-09-2016 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 Spa2297_RS00995 92182dfbefc75605a7d3d8004d37d04d 256 Gene3D G3DSA:3.40.50.10310 4 249 7.2E-67 T 16-09-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 Spa2297_RS18550 97e1709f2e2477571d94bee48a02412b 353 PANTHER PTHR10366:SF5 4 342 3.3E-130 T 16-09-2016 Spa2297_RS18550 97e1709f2e2477571d94bee48a02412b 353 PANTHER PTHR10366 4 342 3.3E-130 T 16-09-2016 Spa2297_RS18550 97e1709f2e2477571d94bee48a02412b 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 184 2.8E-19 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS18550 97e1709f2e2477571d94bee48a02412b 353 Gene3D G3DSA:3.40.50.720 3 212 6.8E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18550 97e1709f2e2477571d94bee48a02412b 353 SUPERFAMILY SSF51735 2 316 1.3E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28365 588b41f15b5693d05a34d31d1da82cb7 387 Pfam PF04909 Amidohydrolase 143 379 5.2E-19 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS28365 588b41f15b5693d05a34d31d1da82cb7 387 Gene3D G3DSA:3.20.20.140 13 379 2.9E-105 T 16-09-2016 Spa2297_RS28365 588b41f15b5693d05a34d31d1da82cb7 387 PANTHER PTHR20852:SF14 300 381 1.5E-28 T 16-09-2016 Spa2297_RS28365 588b41f15b5693d05a34d31d1da82cb7 387 SUPERFAMILY SSF51556 22 380 5.51E-12 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS28365 588b41f15b5693d05a34d31d1da82cb7 387 PANTHER PTHR20852 300 381 1.5E-28 T 16-09-2016 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 55 2.1E-11 T 16-09-2016 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 Gene3D G3DSA:3.50.50.60 3 101 5.9E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 PANTHER PTHR10668 1 467 1.2E-217 T 16-09-2016 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 PANTHER PTHR10668:SF74 1 467 1.2E-217 T 16-09-2016 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 Gene3D G3DSA:3.50.50.60 205 265 9.8E-7 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 Gene3D G3DSA:3.50.50.60 433 467 9.8E-7 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 Gene3D G3DSA:3.50.50.60 300 339 1.7E-8 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS26835 d153a3dbe1eb64dcf4cb759a0d35cd24 469 SUPERFAMILY SSF51905 2 356 2.81E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 PANTHER PTHR30055 1 203 9.0E-67 T 16-09-2016 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 61 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 SUPERFAMILY SSF48498 87 204 1.11E-17 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 PANTHER PTHR30055:SF71 1 203 9.0E-67 T 16-09-2016 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 SUPERFAMILY SSF46689 8 87 4.82E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.3E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.3E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 Gene3D G3DSA:1.10.357.10 2 206 8.4E-47 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS04370 9c5b94c0bd2d8797a6f7843ba09829c7 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.9E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS12945 7e6e6f63ca9afd65363c37ac5b057450 577 SUPERFAMILY SSF53448 15 240 8.75E-47 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12945 7e6e6f63ca9afd65363c37ac5b057450 577 Pfam PF00535 Glycosyl transferase family 2 29 154 4.3E-31 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS12945 7e6e6f63ca9afd65363c37ac5b057450 577 Gene3D G3DSA:3.90.550.10 25 249 2.4E-46 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12945 7e6e6f63ca9afd65363c37ac5b057450 577 PANTHER PTHR22916 21 465 7.1E-82 T 16-09-2016 Spa2297_RS12945 7e6e6f63ca9afd65363c37ac5b057450 577 PANTHER PTHR22916:SF3 21 465 7.1E-82 T 16-09-2016 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 SMART SM00530 31 86 0.0028 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 PANTHER PTHR10245 27 282 3.7E-33 T 16-09-2016 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 Gene3D G3DSA:1.10.260.40 27 80 5.7E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 SUPERFAMILY SSF47413 25 80 3.26E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 PANTHER PTHR10245:SF7 27 282 3.7E-33 T 16-09-2016 Spa2297_RS09390 06d0fe463570709183ba5847f46501ff 284 Pfam PF13560 Helix-turn-helix domain 29 84 8.9E-10 T 16-09-2016 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 SUPERFAMILY SSF51658 16 292 8.38E-72 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 Pfam PF01261 Xylose isomerase-like TIM barrel 32 252 2.6E-26 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 79 87 - T 16-09-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 188 195 - T 16-09-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 SMART SM00518 15 293 1.7E-120 T 16-09-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 Gene3D G3DSA:3.20.20.150 15 293 3.6E-83 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 Hamap MF_00152 Probable endonuclease 4 [nfo]. 14 293 39.697 T 16-09-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 PANTHER PTHR21445 16 294 1.2E-84 T 16-09-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 16 290 6.4E-63 T 16-09-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 Spa2297_RS08665 d9e7e54e7afd03bb35d5b6ecde8440a3 295 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 228 244 - T 16-09-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 SMART SM01091 357 434 2.4E-17 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 SUPERFAMILY SSF54631 213 347 2.02E-25 T 16-09-2016 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 Pfam PF00571 CBS domain 283 335 2.6E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 Gene3D G3DSA:3.30.465.10 331 431 8.2E-21 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 Pfam PF03471 Transporter associated domain 364 430 7.2E-15 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 PANTHER PTHR22777 4 461 1.9E-270 T 16-09-2016 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 SUPERFAMILY SSF56176 362 438 1.12E-15 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 Pfam PF01595 Domain of unknown function DUF21 8 201 2.6E-33 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 Gene3D G3DSA:3.10.580.10 209 330 5.5E-17 T 16-09-2016 Spa2297_RS04560 cfc7a554fb2f40c0ce1f3e253b6047d1 464 PANTHER PTHR22777:SF5 4 461 1.9E-270 T 16-09-2016 Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 PANTHER PTHR12905:SF0 97 249 4.1E-34 T 16-09-2016 Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 PANTHER PTHR12905:SF0 1 78 4.1E-34 T 16-09-2016 Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 SUPERFAMILY SSF56300 83 250 1.44E-33 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 SUPERFAMILY SSF56300 1 42 1.44E-33 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 242 1.1E-7 T 16-09-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 Gene3D G3DSA:3.60.21.10 1 253 1.1E-18 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 PANTHER PTHR12905 97 249 4.1E-34 T 16-09-2016 Spa2297_RS08760 07a9cf0cc614998b30124d3bcc12e9de 253 PANTHER PTHR12905 1 78 4.1E-34 T 16-09-2016 Spa2297_RS12165 8b1e59333fb44521ab055915650ee7ac 254 Gene3D G3DSA:1.10.3720.10 3 252 1.6E-42 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12165 8b1e59333fb44521ab055915650ee7ac 254 PANTHER PTHR30183:SF3 7 254 7.5E-55 T 16-09-2016 Spa2297_RS12165 8b1e59333fb44521ab055915650ee7ac 254 SUPERFAMILY SSF161098 5 242 1.28E-44 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12165 8b1e59333fb44521ab055915650ee7ac 254 PANTHER PTHR30183 7 254 7.5E-55 T 16-09-2016 Spa2297_RS12165 8b1e59333fb44521ab055915650ee7ac 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 243 3.0E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 Pfam PF00171 Aldehyde dehydrogenase family 51 494 1.2E-95 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 SUPERFAMILY SSF53720 46 497 9.42E-75 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 PANTHER PTHR11699:SF198 21 490 2.5E-183 T 16-09-2016 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 PANTHER PTHR11699 21 490 2.5E-183 T 16-09-2016 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 Gene3D G3DSA:3.40.309.10 271 460 7.2E-35 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS27445 98c6ef9f288e9a3cc06447e65ab02aff 518 Gene3D G3DSA:3.40.605.10 40 270 3.0E-35 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 PANTHER PTHR11538 285 348 5.1E-90 T 16-09-2016 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 PANTHER PTHR11538 86 267 5.1E-90 T 16-09-2016 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 Pfam PF01409 tRNA synthetases class II core domain (F) 86 345 1.6E-102 T 16-09-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 SUPERFAMILY SSF46589 6 92 6.28E-14 T 16-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 14 81 1.7E-15 T 16-09-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 SUPERFAMILY SSF55681 86 347 9.69E-73 T 16-09-2016 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 45 344 2.5E-84 T 16-09-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 346 45.453 T 16-09-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 Spa2297_RS06145 79365d24346440ad5db3920b65c55ed4 350 Gene3D G3DSA:3.30.930.10 2 347 2.6E-114 T 16-09-2016 Spa2297_RS07695 24f1463264125403c29f7fdd8c80c4fd 243 SUPERFAMILY SSF47413 4 61 1.1E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS07695 24f1463264125403c29f7fdd8c80c4fd 243 SUPERFAMILY SSF56024 80 191 1.1E-6 T 16-09-2016 Spa2297_RS07695 24f1463264125403c29f7fdd8c80c4fd 243 Gene3D G3DSA:1.10.260.40 3 60 5.2E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS07695 24f1463264125403c29f7fdd8c80c4fd 243 Gene3D G3DSA:3.30.870.10 90 158 3.6E-4 T 16-09-2016 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 SUPERFAMILY SSF53795 246 605 4.35E-160 T 16-09-2016 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 PIRSF PIRSF001348 2 606 6.9E-281 T 16-09-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 270 278 - T 16-09-2016 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 PANTHER PTHR11561 2 605 0.0 T 16-09-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 8 606 52.567 T 16-09-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 Gene3D G3DSA:3.40.449.10 10 245 1.3E-98 T 16-09-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 Gene3D G3DSA:3.90.228.20 246 315 3.7E-32 T 16-09-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 Gene3D G3DSA:3.90.228.20 332 605 5.0E-103 T 16-09-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase 19 605 3.2E-283 T 16-09-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 SUPERFAMILY SSF68923 9 245 1.46E-97 T 16-09-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 Spa2297_RS21070 5c1df5c8c1d642613eecca1a436e9b10 606 PANTHER PTHR11561:SF0 2 605 0.0 T 16-09-2016 Spa2297_RS28905 b604290ee5f2421f43b3c1f4402f1664 303 PANTHER PTHR32243:SF38 26 303 1.9E-150 T 16-09-2016 Spa2297_RS28905 b604290ee5f2421f43b3c1f4402f1664 303 SUPERFAMILY SSF161098 33 303 5.76E-67 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28905 b604290ee5f2421f43b3c1f4402f1664 303 PANTHER PTHR32243 26 303 1.9E-150 T 16-09-2016 Spa2297_RS28905 b604290ee5f2421f43b3c1f4402f1664 303 Gene3D G3DSA:1.10.3720.10 29 290 9.5E-63 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28905 b604290ee5f2421f43b3c1f4402f1664 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 296 3.5E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 SUPERFAMILY SSF103473 14 206 3.01E-47 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 SUPERFAMILY SSF103473 252 460 3.01E-47 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 Gene3D G3DSA:1.20.1250.20 14 193 2.5E-26 T 16-09-2016 Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 Gene3D G3DSA:1.20.1250.20 268 460 4.6E-16 T 16-09-2016 Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 Pfam PF07690 Major Facilitator Superfamily 25 296 1.2E-22 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 PANTHER PTHR23501:SF15 9 463 3.8E-131 T 16-09-2016 Spa2297_RS31685 b605d0f8929dd232602f5b2982a2c527 466 PANTHER PTHR23501 9 463 3.8E-131 T 16-09-2016 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Gene3D G3DSA:1.10.10.10 105 162 8.1E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 SUPERFAMILY SSF88659 82 164 1.14E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Pfam PF08281 Sigma-70, region 4 109 160 2.9E-11 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Gene3D G3DSA:3.10.450.50 171 288 4.6E-18 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 SUPERFAMILY SSF88946 12 90 3.06E-14 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 160 3.6E-19 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 PANTHER PTHR30173 11 289 7.4E-122 T 16-09-2016 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 SUPERFAMILY SSF54427 173 289 2.36E-21 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Gene3D G3DSA:1.10.1740.10 11 78 5.3E-14 T 16-09-2016 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 PANTHER PTHR30173:SF25 11 289 7.4E-122 T 16-09-2016 Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Pfam PF12680 SnoaL-like domain 182 275 6.7E-7 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 11 289 2.5E-106 T 16-09-2016 IPR014303 RNA polymerase sigma-70, ECF type Spa2297_RS32185 0a9728409aa910001cbba3004d4ff277 298 Pfam PF04542 Sigma-70 region 2 15 77 5.0E-15 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 PANTHER PTHR30328 2 159 7.7E-37 T 16-09-2016 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 SUPERFAMILY SSF46689 4 84 1.69E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 PANTHER PTHR30328:SF24 2 159 7.7E-37 T 16-09-2016 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 Gene3D G3DSA:1.10.357.10 13 186 1.1E-26 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.0E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 SUPERFAMILY SSF48498 81 192 2.03E-16 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS00375 476b49c4642a31c1d82e598dc7f4d30c 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 5.4E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS31165 01d2626c0086b105eeabdb258a3b438a 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 6.9E-13 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS31165 01d2626c0086b105eeabdb258a3b438a 128 Gene3D G3DSA:3.10.180.10 1 126 3.5E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS31165 01d2626c0086b105eeabdb258a3b438a 128 PANTHER PTHR36437 1 124 3.0E-80 T 16-09-2016 Spa2297_RS31165 01d2626c0086b105eeabdb258a3b438a 128 PANTHER PTHR36437:SF1 1 124 3.0E-80 T 16-09-2016 Spa2297_RS31165 01d2626c0086b105eeabdb258a3b438a 128 SUPERFAMILY SSF54593 1 125 4.97E-25 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 Pfam PF02040 Arsenical pump membrane protein 5 394 8.2E-23 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 PANTHER PTHR10283 2 408 2.7E-102 T 16-09-2016 Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 PANTHER PTHR10283:SF21 2 408 2.7E-102 T 16-09-2016 Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 PRINTS PR00758 Arsenical pump membrane protein signature 95 119 1.8E-16 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 PRINTS PR00758 Arsenical pump membrane protein signature 168 191 1.8E-16 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS01840 bddb7282a13641e044b23fd4ca8d3c4b 410 PRINTS PR00758 Arsenical pump membrane protein signature 344 369 1.8E-16 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 Pfam PF01476 LysM domain 288 335 8.1E-7 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 Gene3D G3DSA:1.10.530.10 18 121 1.2E-35 T 16-09-2016 Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 SUPERFAMILY SSF54106 287 336 1.12E-5 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 Pfam PF06737 Transglycosylase-like domain 41 115 6.8E-32 T 16-09-2016 IPR010618 Transglycosylase-like Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 SUPERFAMILY SSF53955 40 121 1.07E-25 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 Gene3D G3DSA:3.10.350.10 287 336 1.7E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS13455 e35c893f642003f8a8a9a72eba7fa087 342 SMART SM00257 287 336 6.0E-8 T 16-09-2016 IPR018392 LysM domain Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Gene3D G3DSA:3.30.1490.20 22 85 5.5E-17 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Gene3D G3DSA:3.30.470.20 86 229 1.8E-50 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 16-09-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Pfam PF08442 ATP-grasp domain 2 195 1.1E-66 T 16-09-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 7.2E-124 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 41.051 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 SUPERFAMILY SSF56059 3 228 2.75E-63 T 16-09-2016 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 PIRSF PIRSF001554 1 392 5.8E-137 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 SUPERFAMILY SSF52210 232 389 9.94E-42 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Gene3D G3DSA:3.40.50.261 233 389 2.1E-52 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 Pfam PF00549 CoA-ligase 257 377 6.9E-14 T 16-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS20295 2aad73c693b640a93fafeb8821196f41 394 PANTHER PTHR11815 2 393 4.2E-167 T 16-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992 182 273 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 SUPERFAMILY SSF53474 77 136 1.18E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 SUPERFAMILY SSF53474 175 239 1.18E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 SUPERFAMILY SSF53474 323 467 1.18E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 Gene3D G3DSA:3.40.50.1820 184 308 2.2E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 Gene3D G3DSA:3.40.50.1820 362 481 2.2E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 Gene3D G3DSA:3.40.50.1820 57 141 2.2E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992:SF878 182 273 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992:SF878 370 483 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992:SF878 63 140 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 Pfam PF00561 alpha/beta hydrolase fold 91 273 2.8E-31 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992 370 483 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 PANTHER PTHR10992 63 140 7.4E-43 T 16-09-2016 Spa2297_RS26965 fae6e83e4ab7a25f9afd27fdb8efeeea 533 Pfam PF08386 TAP-like protein 395 488 1.6E-24 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 Pfam PF13378 Enolase C-terminal domain-like 137 359 7.0E-64 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 Gene3D G3DSA:3.20.20.120 117 357 5.9E-91 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 SMART SM00922 132 237 1.6E-26 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 PANTHER PTHR13794:SF4 5 385 5.9E-142 T 16-09-2016 Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 111 2.0E-17 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 SUPERFAMILY SSF51604 99 366 1.26E-81 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 SUPERFAMILY SSF54826 2 115 6.9E-28 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 PANTHER PTHR13794 5 385 5.9E-142 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS10105 697c79805e695a5cd59dc85171346adf 388 Gene3D G3DSA:3.30.390.10 10 116 1.2E-38 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PANTHER PTHR11444 26 475 2.3E-134 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 Pfam PF00206 Lyase 31 319 1.6E-35 T 16-09-2016 IPR022761 Fumarate lyase, N-terminal Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PANTHER PTHR11444:SF21 26 475 2.3E-134 T 16-09-2016 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 1.6E-15 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 1.6E-15 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 1.6E-15 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 PRINTS PR00149 Fumarate lyase superfamily signature 296 312 1.6E-15 T 16-09-2016 IPR000362 Fumarate lyase family Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 Gene3D G3DSA:1.10.275.10 17 107 1.3E-24 T 16-09-2016 IPR024083 Fumarase/histidase, N-terminal Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 Pfam PF10397 Adenylosuccinate lyase C-terminus 385 461 4.1E-13 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 SMART SM00998 384 463 1.6E-15 T 16-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 Gene3D G3DSA:1.20.200.10 108 390 1.4E-86 T 16-09-2016 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 SUPERFAMILY SSF48557 24 464 1.35E-87 T 16-09-2016 IPR008948 L-Aspartase-like GO:0003824 Spa2297_RS26595 fa1a76d9fa695e6118e1e5c7058c6d99 478 Gene3D G3DSA:1.10.40.30 391 463 6.3E-20 T 16-09-2016 Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 339 1.6E-122 T 16-09-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 350 40.123 T 16-09-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 166 2.2E-15 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 343 8.2E-33 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 SUPERFAMILY SSF55326 8 171 1.41E-44 T 16-09-2016 Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 Gene3D G3DSA:3.30.1330.10 23 171 5.2E-51 T 16-09-2016 IPR016188 PurM-like, N-terminal domain Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 PANTHER PTHR10520 7 353 1.6E-165 T 16-09-2016 Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 Gene3D G3DSA:3.90.650.10 175 344 7.4E-61 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS15760 de33a39fcf6609c8a2ac8682092790e6 355 SUPERFAMILY SSF56042 175 343 1.94E-51 T 16-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain Spa2297_RS12715 1f1667fb535a387a47a243805646ae9e 285 SUPERFAMILY SSF161098 13 279 3.18E-67 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12715 1f1667fb535a387a47a243805646ae9e 285 PANTHER PTHR32243:SF42 9 285 1.1E-149 T 16-09-2016 Spa2297_RS12715 1f1667fb535a387a47a243805646ae9e 285 Gene3D G3DSA:1.10.3720.10 11 273 4.1E-65 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12715 1f1667fb535a387a47a243805646ae9e 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 1.8E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12715 1f1667fb535a387a47a243805646ae9e 285 PANTHER PTHR32243 9 285 1.1E-149 T 16-09-2016 Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 264 1.3E-47 T 16-09-2016 Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 20 266 8.5E-106 T 16-09-2016 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.7E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 9.7E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.7E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 SUPERFAMILY SSF51735 15 265 7.36E-73 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.0E-35 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PANTHER PTHR24322 24 145 6.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PANTHER PTHR24322 161 193 6.9E-46 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 Gene3D G3DSA:3.40.50.720 11 265 3.4E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PANTHER PTHR24322:SF649 161 193 6.9E-46 T 16-09-2016 Spa2297_RS03360 274ec876629ee77c0f42b50616ac30a6 266 PANTHER PTHR24322:SF649 24 145 6.9E-46 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 PANTHER PTHR22754 145 497 3.7E-41 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 PANTHER PTHR22754:SF30 145 497 3.7E-41 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 SUPERFAMILY SSF56801 12 505 1.16E-78 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 Gene3D G3DSA:3.40.50.980 11 158 3.5E-20 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 Gene3D G3DSA:2.30.38.10 341 407 4.8E-11 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 Gene3D G3DSA:3.40.50.980 159 325 1.6E-23 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 Gene3D G3DSA:3.30.300.30 410 502 3.3E-7 T 16-09-2016 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 Pfam PF00501 AMP-binding enzyme 23 413 1.7E-50 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS26690 235f1ff09c795b0a1cca42cde8ca7fdc 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 PANTHER PTHR11098:SF1 7 439 5.9E-149 T 16-09-2016 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 SUPERFAMILY SSF54675 5 131 2.83E-30 T 16-09-2016 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 SUPERFAMILY SSF51690 133 435 5.74E-90 T 16-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 150 230 1.2E-6 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 6 424 1.7E-131 T 16-09-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 PANTHER PTHR11098 7 439 5.9E-149 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 Gene3D G3DSA:3.20.140.10 4 358 1.0E-84 T 16-09-2016 Spa2297_RS03920 06c9f1571e6ae3a179e9a57588ef01e6 439 PIRSF PIRSF000484 1 439 2.3E-122 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS21320 161a3981bfd2da6005cb5c845bcd67a0 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 2.2E-14 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS21320 161a3981bfd2da6005cb5c845bcd67a0 174 PANTHER PTHR33169 1 170 2.3E-67 T 16-09-2016 Spa2297_RS21320 161a3981bfd2da6005cb5c845bcd67a0 174 SUPERFAMILY SSF46785 3 167 2.46E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21320 161a3981bfd2da6005cb5c845bcd67a0 174 Gene3D G3DSA:1.10.10.10 1 87 1.6E-25 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21320 161a3981bfd2da6005cb5c845bcd67a0 174 PANTHER PTHR33169:SF2 1 170 2.3E-67 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953 233 335 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953 351 556 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953 55 211 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 Pfam PF09423 PhoD-like phosphatase 169 526 1.8E-117 T 16-09-2016 IPR018946 Alkaline phosphatase D-related Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 SUPERFAMILY SSF56300 166 531 1.14E-29 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953:SF28 233 335 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953:SF28 55 211 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 PANTHER PTHR22953:SF28 351 556 1.2E-112 T 16-09-2016 Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 Gene3D G3DSA:3.60.21.10 483 532 3.2E-12 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 Gene3D G3DSA:3.60.21.10 171 448 3.2E-12 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS08445 d9f884e6a71597a516d972c6309491a6 561 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 60 156 7.4E-30 T 16-09-2016 IPR032093 Phospholipase D, N-terminal Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 Pfam PF00230 Major intrinsic protein 7 248 6.6E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 5 24 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 83 102 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 152 170 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 184 206 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 47 71 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PRINTS PR00783 Major intrinsic protein family signature 231 251 2.8E-41 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PANTHER PTHR19139:SF147 1 252 1.5E-76 T 16-09-2016 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 SUPERFAMILY SSF81338 7 251 3.4E-59 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 248 2.7E-51 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 ProSitePatterns PS00221 MIP family signature. 65 73 - T 16-09-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 Gene3D G3DSA:1.20.1080.10 6 251 7.6E-76 T 16-09-2016 IPR023271 Aquaporin-like Spa2297_RS05160 241ed4cc4e030f162479132f75a85b14 252 PANTHER PTHR19139 1 252 1.5E-76 T 16-09-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 Gene3D G3DSA:3.40.640.10 20 266 1.3E-52 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 SUPERFAMILY SSF53383 12 371 1.97E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 PIRSF PIRSF000525 1 372 3.4E-75 T 16-09-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 Pfam PF00266 Aminotransferase class-V 18 331 2.5E-20 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.973 T 16-09-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 372 4.6E-221 T 16-09-2016 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 PANTHER PTHR21152:SF20 3 372 1.4E-191 T 16-09-2016 Spa2297_RS14555 6959b2e1ca08c1a09bc89de88bffe2de 372 PANTHER PTHR21152 3 372 1.4E-191 T 16-09-2016 Spa2297_RS04740 fc49fc031600da1ac7db2617b436593a 562 PANTHER PTHR33361:SF6 12 561 1.0E-168 T 16-09-2016 Spa2297_RS04740 fc49fc031600da1ac7db2617b436593a 562 PANTHER PTHR33361 12 561 1.0E-168 T 16-09-2016 Spa2297_RS04740 fc49fc031600da1ac7db2617b436593a 562 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 557 2.3E-144 T 16-09-2016 IPR010281 Protein of unknown function DUF885 Spa2297_RS00395 ff3abb0aca8a7caf1ded6f4344a62768 232 Gene3D G3DSA:1.25.40.290 131 221 3.6E-19 T 16-09-2016 Spa2297_RS00395 ff3abb0aca8a7caf1ded6f4344a62768 232 PANTHER PTHR34070:SF1 6 231 4.1E-35 T 16-09-2016 Spa2297_RS00395 ff3abb0aca8a7caf1ded6f4344a62768 232 PANTHER PTHR34070 6 231 4.1E-35 T 16-09-2016 Spa2297_RS00395 ff3abb0aca8a7caf1ded6f4344a62768 232 SUPERFAMILY SSF48371 12 220 4.37E-37 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS00395 ff3abb0aca8a7caf1ded6f4344a62768 232 Pfam PF08713 DNA alkylation repair enzyme 10 220 4.7E-52 T 16-09-2016 IPR014825 DNA alkylation repair enzyme Spa2297_RS09480 69dab7e1de9cda2eef91e7484cb1f136 514 Pfam PF04213 Htaa 45 191 4.7E-22 T 16-09-2016 IPR007331 Htaa Spa2297_RS09480 69dab7e1de9cda2eef91e7484cb1f136 514 Pfam PF04213 Htaa 260 420 1.2E-43 T 16-09-2016 IPR007331 Htaa Spa2297_RS09480 69dab7e1de9cda2eef91e7484cb1f136 514 PANTHER PTHR23246:SF4 155 287 2.3E-26 T 16-09-2016 Spa2297_RS09480 69dab7e1de9cda2eef91e7484cb1f136 514 PANTHER PTHR23246 155 287 2.3E-26 T 16-09-2016 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 417 528 1.8E-22 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 SUPERFAMILY SSF55604 470 542 6.54E-20 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 5 542 1.0E-289 T 16-09-2016 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 Pfam PF00367 phosphotransferase system, EIIB 471 503 1.7E-12 T 16-09-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 Pfam PF02378 Phosphotransferase system, EIIC 16 358 1.0E-72 T 16-09-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 481 498 - T 16-09-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 PANTHER PTHR30009 9 545 0.0 T 16-09-2016 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 PANTHER PTHR30009:SF1 9 545 0.0 T 16-09-2016 Spa2297_RS31320 5f322e4a3f643300c06105a97e687328 545 Gene3D G3DSA:3.30.1360.60 469 541 2.9E-26 T 16-09-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 Spa2297_RS24260 aab6e389499d5d6b548d36ed6b8b25f6 246 Pfam PF02511 Thymidylate synthase complementing protein 21 232 6.5E-50 T 16-09-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS24260 aab6e389499d5d6b548d36ed6b8b25f6 246 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 19 238 2.0E-63 T 16-09-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS24260 aab6e389499d5d6b548d36ed6b8b25f6 246 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 13 246 27.125 T 16-09-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS24260 aab6e389499d5d6b548d36ed6b8b25f6 246 PANTHER PTHR34934 12 241 3.4E-58 T 16-09-2016 Spa2297_RS24260 aab6e389499d5d6b548d36ed6b8b25f6 246 SUPERFAMILY SSF69796 12 239 7.45E-51 T 16-09-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PANTHER PTHR11533:SF185 1 13 3.4E-170 T 16-09-2016 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 351 363 1.1E-11 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 332 347 1.1E-11 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 177 192 1.1E-11 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PANTHER PTHR11533:SF185 40 493 3.4E-170 T 16-09-2016 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PANTHER PTHR11533 40 493 3.4E-170 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 Pfam PF01433 Peptidase family M1 66 383 5.7E-34 T 16-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 SUPERFAMILY SSF63737 50 240 1.44E-31 T 16-09-2016 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 Gene3D G3DSA:1.10.390.10 346 486 2.8E-19 T 16-09-2016 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 SUPERFAMILY SSF55486 249 485 1.83E-51 T 16-09-2016 Spa2297_RS24530 4d79e34914940beaf009cbc55c43ab32 509 PANTHER PTHR11533 1 13 3.4E-170 T 16-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 PANTHER PTHR30328:SF8 1 136 1.7E-22 T 16-09-2016 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 SUPERFAMILY SSF46689 14 83 6.48E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 2.0E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.7E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.7E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 SUPERFAMILY SSF48498 103 238 3.11E-22 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 Gene3D G3DSA:1.10.357.10 11 230 2.4E-39 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS01100 1f61484a49aeb21a5216cfa6d305f673 248 PANTHER PTHR30328 1 136 1.7E-22 T 16-09-2016 Spa2297_RS29720 37309cf8fc07684145b3ac51afb01ea0 403 Gene3D G3DSA:2.130.10.10 67 390 5.6E-89 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS29720 37309cf8fc07684145b3ac51afb01ea0 403 PANTHER PTHR30344 58 385 4.2E-101 T 16-09-2016 Spa2297_RS29720 37309cf8fc07684145b3ac51afb01ea0 403 PANTHER PTHR30344:SF1 58 385 4.2E-101 T 16-09-2016 Spa2297_RS29720 37309cf8fc07684145b3ac51afb01ea0 403 SUPERFAMILY SSF51004 84 382 3.01E-50 T 16-09-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain Spa2297_RS29720 37309cf8fc07684145b3ac51afb01ea0 403 Pfam PF10282 Lactonase, 7-bladed beta-propeller 67 399 1.6E-99 T 16-09-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 Spa2297_RS30790 2f742466bfd544f41c2e7a49457edd1d 334 SUPERFAMILY SSF56112 32 306 2.24E-13 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS30790 2f742466bfd544f41c2e7a49457edd1d 334 Gene3D G3DSA:3.90.1200.10 163 282 7.5E-4 T 16-09-2016 Spa2297_RS30790 2f742466bfd544f41c2e7a49457edd1d 334 Pfam PF01636 Phosphotransferase enzyme family 80 270 2.6E-6 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 SMART SM00054 134 162 1.9 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 SMART SM00054 100 128 7.9 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 SMART SM00054 9 37 0.79 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 ProSitePatterns PS00018 EF-hand calcium-binding domain. 143 155 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 Gene3D G3DSA:1.10.238.10 106 159 6.9E-10 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 Gene3D G3DSA:1.10.238.10 74 105 2.4E-5 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 ProSitePatterns PS00018 EF-hand calcium-binding domain. 18 30 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 Pfam PF13833 EF-hand domain pair 9 36 8.5E-5 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 Pfam PF13499 EF-hand domain pair 103 158 2.2E-8 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 Gene3D G3DSA:1.10.238.10 7 54 3.6E-10 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS31820 a5d0369bbe1bdbfd4d841eddd46c8c8c 183 SUPERFAMILY SSF47473 3 178 9.28E-24 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS05780 d99250eed6a50d1d39ae943052f20d08 180 Pfam PF04011 LemA family 8 139 5.0E-7 T 16-09-2016 IPR007156 LemA Spa2297_RS05780 d99250eed6a50d1d39ae943052f20d08 180 SUPERFAMILY SSF140478 27 139 1.01E-6 T 16-09-2016 IPR023353 LemA-like domain Spa2297_RS05780 d99250eed6a50d1d39ae943052f20d08 180 Gene3D G3DSA:1.20.1440.20 21 139 1.5E-7 T 16-09-2016 IPR023353 LemA-like domain Spa2297_RS29605 01c4a69bb583ebaaad57bcf9abff3383 223 PANTHER PTHR30177 20 216 1.0E-48 T 16-09-2016 Spa2297_RS29605 01c4a69bb583ebaaad57bcf9abff3383 223 SUPERFAMILY SSF161098 21 205 1.31E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS29605 01c4a69bb583ebaaad57bcf9abff3383 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 207 2.1E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS29605 01c4a69bb583ebaaad57bcf9abff3383 223 PANTHER PTHR30177:SF4 20 216 1.0E-48 T 16-09-2016 Spa2297_RS29605 01c4a69bb583ebaaad57bcf9abff3383 223 Gene3D G3DSA:1.10.3720.10 8 213 2.6E-26 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Pfam PF13581 Histidine kinase-like ATPase domain 750 858 7.3E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SUPERFAMILY SSF81606 531 736 3.66E-9 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Pfam PF01590 GAF domain 338 489 2.4E-8 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SMART SM00065 335 499 4.6E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SUPERFAMILY SSF55874 782 858 3.54E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SMART SM00091 205 270 0.0027 T 16-09-2016 IPR000014 PAS domain Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Pfam PF17203 Single cache domain 3 29 157 4.1E-30 T 16-09-2016 IPR033463 Single cache domain 3 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SUPERFAMILY SSF103190 35 158 4.32E-36 T 16-09-2016 IPR029151 Periplasmic sensor domain-like Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 PANTHER PTHR21021:SF19 441 746 1.6E-61 T 16-09-2016 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Gene3D G3DSA:3.30.450.20 206 302 4.6E-6 T 16-09-2016 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SUPERFAMILY SSF55785 200 302 4.4E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 PANTHER PTHR21021 441 746 1.6E-61 T 16-09-2016 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SMART SM00331 517 737 1.8E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Gene3D G3DSA:3.30.450.40 324 497 2.5E-37 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Gene3D G3DSA:3.30.450.20 25 163 3.2E-46 T 16-09-2016 Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 SUPERFAMILY SSF55781 339 499 3.71E-16 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS30310 a5edc2d0a2cc8bf8ad3549e62550b066 864 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 545 737 8.6E-53 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 Pfam PF00171 Aldehyde dehydrogenase family 7 455 1.0E-160 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 SUPERFAMILY SSF53720 8 457 3.4E-155 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 Gene3D G3DSA:3.40.309.10 250 435 3.9E-57 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 PANTHER PTHR11699:SF46 10 458 4.8E-209 T 16-09-2016 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 PANTHER PTHR11699 10 458 4.8E-209 T 16-09-2016 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 235 242 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 263 274 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS06215 08da0010a2f20d9e996477d06778b501 469 Gene3D G3DSA:3.40.605.10 6 249 1.6E-90 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 PANTHER PTHR30328 1 114 8.3E-33 T 16-09-2016 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 1.3E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 Gene3D G3DSA:1.10.10.60 11 81 6.5E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 91 207 4.1E-10 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 SUPERFAMILY SSF48498 90 231 1.67E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 Gene3D G3DSA:1.10.357.10 88 231 5.7E-49 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 SUPERFAMILY SSF46689 22 86 1.16E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30815 5a7a4b25b72ad5eb42adc155d881b09f 238 PANTHER PTHR30328:SF17 1 114 8.3E-33 T 16-09-2016 Spa2297_RS01785 ba41f5fd3b201224ed53d12f0955107c 437 PANTHER PTHR16254:SF5 10 373 4.9E-191 T 16-09-2016 Spa2297_RS01785 ba41f5fd3b201224ed53d12f0955107c 437 Pfam PF00999 Sodium/hydrogen exchanger family 15 373 3.0E-61 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS01785 ba41f5fd3b201224ed53d12f0955107c 437 PANTHER PTHR16254 10 373 4.9E-191 T 16-09-2016 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 Gene3D G3DSA:3.40.720.10 158 334 2.3E-12 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 Gene3D G3DSA:3.40.720.10 366 448 2.3E-12 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 20 129 4.1E-9 T 16-09-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 SUPERFAMILY SSF53649 164 250 3.6E-12 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 SUPERFAMILY SSF53649 316 324 3.6E-12 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 SUPERFAMILY SSF53649 367 449 3.6E-12 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS27200 b2c19bd8d10f04fe66b27d2bf0b58695 714 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 230 484 5.5E-7 T 16-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Spa2297_RS17065 efcc423c04484b2cdcc8a2ee0d6003e4 326 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 12 314 2.3E-66 T 16-09-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain Spa2297_RS17065 efcc423c04484b2cdcc8a2ee0d6003e4 326 Gene3D G3DSA:3.90.245.10 10 323 1.0E-95 T 16-09-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain Spa2297_RS17065 efcc423c04484b2cdcc8a2ee0d6003e4 326 PANTHER PTHR12304:SF15 7 326 3.3E-181 T 16-09-2016 Spa2297_RS17065 efcc423c04484b2cdcc8a2ee0d6003e4 326 SUPERFAMILY SSF53590 10 323 5.23E-85 T 16-09-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain Spa2297_RS17065 efcc423c04484b2cdcc8a2ee0d6003e4 326 PANTHER PTHR12304 7 326 3.3E-181 T 16-09-2016 IPR023186 Inosine/uridine-preferring nucleoside hydrolase Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 Pfam PF01479 S4 domain 7 49 2.2E-10 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 SMART SM00363 7 74 1.4E-6 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 3.0E-18 T 16-09-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 Gene3D G3DSA:3.40.50.150 97 184 1.6E-12 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 PIRSF PIRSF005578 3 268 3.7E-94 T 16-09-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 SUPERFAMILY SSF53335 60 251 2.49E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 1.7E-59 T 16-09-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 Gene3D G3DSA:3.10.290.10 7 96 3.2E-23 T 16-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 PANTHER PTHR32319 1 271 1.9E-117 T 16-09-2016 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 SUPERFAMILY SSF55174 6 59 3.68E-11 T 16-09-2016 Spa2297_RS07040 a3cc1891a1a2628bcb8ac77890680b16 271 PANTHER PTHR32319:SF0 1 271 1.9E-117 T 16-09-2016 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 173 195 - T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 313 326 2.1E-9 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 259 267 2.1E-9 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 173 187 2.1E-9 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 146 158 2.1E-9 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 PANTHER PTHR11705 128 337 2.5E-67 T 16-09-2016 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 Pfam PF05547 Immune inhibitor A peptidase M6 749 916 5.4E-11 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 SMART SM00631 120 409 1.4E-70 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 Pfam PF00246 Zinc carboxypeptidase 133 392 9.3E-59 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 Gene3D G3DSA:3.40.630.10 126 438 3.5E-74 T 16-09-2016 Spa2297_RS07855 a536ef2fcb5c89a26d63b06952cc9cb1 984 SUPERFAMILY SSF53187 127 401 1.68E-63 T 16-09-2016 Spa2297_RS32095 1a7fe2f96713ddb8eff18869fae3667c 303 PANTHER PTHR30193 8 303 2.1E-141 T 16-09-2016 Spa2297_RS32095 1a7fe2f96713ddb8eff18869fae3667c 303 PANTHER PTHR30193:SF15 8 303 2.1E-141 T 16-09-2016 Spa2297_RS32095 1a7fe2f96713ddb8eff18869fae3667c 303 Gene3D G3DSA:1.10.3720.10 18 286 5.2E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32095 1a7fe2f96713ddb8eff18869fae3667c 303 SUPERFAMILY SSF161098 61 285 3.14E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS32095 1a7fe2f96713ddb8eff18869fae3667c 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 288 3.7E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 343 361 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 225 243 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 253 272 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 455 475 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 115 137 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PRINTS PR00175 Sodium/alanine symporter signature 394 416 2.8E-45 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 TIGRFAM TIGR00835 agcS: amino acid carrier protein 43 484 3.7E-112 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PANTHER PTHR30330:SF3 41 491 1.5E-193 T 16-09-2016 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 PANTHER PTHR30330 41 491 1.5E-193 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS18750 fffb7ec1b142c7c5f4637c156d87e568 512 Pfam PF01235 Sodium:alanine symporter family 79 488 2.9E-125 T 16-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 Spa2297_RS17140 ddb30c20e1d9617f001067113691ddd4 242 PANTHER PTHR10859 1 229 3.3E-60 T 16-09-2016 Spa2297_RS17140 ddb30c20e1d9617f001067113691ddd4 242 Gene3D G3DSA:3.90.550.10 12 192 1.8E-19 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS17140 ddb30c20e1d9617f001067113691ddd4 242 PANTHER PTHR10859:SF95 1 229 3.3E-60 T 16-09-2016 Spa2297_RS17140 ddb30c20e1d9617f001067113691ddd4 242 Pfam PF00535 Glycosyl transferase family 2 14 161 2.4E-20 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS17140 ddb30c20e1d9617f001067113691ddd4 242 SUPERFAMILY SSF53448 7 216 2.81E-38 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS11575 8a986a3a0a8831d4da62eb358af8a3af 185 SUPERFAMILY SSF52980 15 150 1.18E-11 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS11575 8a986a3a0a8831d4da62eb358af8a3af 185 Pfam PF05685 Putative restriction endonuclease 9 159 3.3E-16 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS11575 8a986a3a0a8831d4da62eb358af8a3af 185 Gene3D G3DSA:3.90.1570.10 15 150 8.3E-12 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 PANTHER PTHR24220 8 253 4.7E-109 T 16-09-2016 Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 SUPERFAMILY SSF52540 7 228 4.69E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 PANTHER PTHR24220:SF309 8 253 4.7E-109 T 16-09-2016 Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 Gene3D G3DSA:3.40.50.300 6 234 2.8E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 SMART SM00382 31 215 1.7E-16 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 Pfam PF00005 ABC transporter 23 171 7.1E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00645 e61a0c358e051cfcfffe36b0d0a5b61d 260 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 SUPERFAMILY SSF46955 37 150 6.41E-29 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 49 62 5.5E-6 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 49 5.5E-6 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 73 93 5.5E-6 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 Pfam PF13411 MerR HTH family regulatory protein 37 98 6.6E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 PANTHER PTHR30204 29 148 2.2E-64 T 16-09-2016 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 PANTHER PTHR30204:SF2 29 148 2.2E-64 T 16-09-2016 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 SMART SM00422 37 106 5.9E-17 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS10010 0b03b94abb555f2f77e0d4068688fc21 161 Gene3D G3DSA:1.10.1660.10 37 151 8.1E-31 T 16-09-2016 Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 SUPERFAMILY SSF53955 77 273 1.46E-59 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 Gene3D G3DSA:3.40.710.10 262 712 5.0E-95 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 SUPERFAMILY SSF56601 294 677 9.82E-80 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 SUPERFAMILY SSF56601 247 265 9.82E-80 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 Pfam PF00912 Transglycosylase 85 261 7.1E-57 T 16-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 PANTHER PTHR32282:SF8 15 768 0.0 T 16-09-2016 Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 Gene3D G3DSA:1.10.3810.10 85 261 2.2E-62 T 16-09-2016 Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 PANTHER PTHR32282 15 768 0.0 T 16-09-2016 Spa2297_RS21335 21a69ddf2cf9c7520bc4a1cfd642ad27 768 Pfam PF00905 Penicillin binding protein transpeptidase domain 369 619 8.8E-39 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 SUPERFAMILY SSF48403 14 127 2.49E-20 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 PANTHER PTHR24124:SF9 3 117 1.4E-62 T 16-09-2016 Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 Pfam PF12796 Ankyrin repeats (3 copies) 27 105 3.8E-11 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 Gene3D G3DSA:1.25.40.20 14 108 7.0E-21 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 PANTHER PTHR24124 3 117 1.4E-62 T 16-09-2016 Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 SMART SM00248 77 106 0.09 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS05295 6cd8dc58404f9cade6b31621c0584a05 130 SMART SM00248 44 73 0.48 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS00970 63743943683b27baed37df0b0c060f73 740 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 468 732 1.3E-76 T 16-09-2016 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50 Spa2297_RS00970 63743943683b27baed37df0b0c060f73 740 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 140 459 1.7E-99 T 16-09-2016 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50 Spa2297_RS00970 63743943683b27baed37df0b0c060f73 740 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 45 125 1.8E-18 T 16-09-2016 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50 Spa2297_RS00970 63743943683b27baed37df0b0c060f73 740 PANTHER PTHR12872:SF1 9 730 3.4E-161 T 16-09-2016 Spa2297_RS00970 63743943683b27baed37df0b0c060f73 740 PANTHER PTHR12872 9 730 3.4E-161 T 16-09-2016 IPR007781 Alpha-N-acetylglucosaminidase KEGG: 00531+3.2.1.50 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 SUPERFAMILY SSF49899 45 264 5.43E-74 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 Pfam PF01670 Glycosyl hydrolase family 12 59 263 9.2E-77 T 16-09-2016 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 PANTHER PTHR34002 9 268 6.6E-44 T 16-09-2016 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 Pfam PF00553 Cellulose binding domain 285 384 1.3E-30 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 SUPERFAMILY SSF49384 281 385 5.44E-33 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 Gene3D G3DSA:2.60.40.290 284 385 5.7E-37 T 16-09-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 Gene3D G3DSA:2.60.120.180 45 266 4.6E-79 T 16-09-2016 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784|UniPathway: UPA00114 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 PANTHER PTHR34002:SF5 9 268 6.6E-44 T 16-09-2016 Spa2297_RS04285 33d3e3270b0dccd6999f160df9752f22 387 SMART SM00637 285 384 3.4E-48 T 16-09-2016 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 205 218 - T 16-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 PANTHER PTHR11751:SF3 7 355 5.5E-70 T 16-09-2016 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 Pfam PF00155 Aminotransferase class I and II 28 347 2.5E-30 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 PANTHER PTHR11751 7 355 5.5E-70 T 16-09-2016 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 SUPERFAMILY SSF53383 21 350 9.15E-59 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 Gene3D G3DSA:3.90.1150.10 248 351 1.4E-16 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07415 31b5543d578c740e694ef78cbcb4b464 356 Gene3D G3DSA:3.40.640.10 39 247 1.3E-49 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS22290 6c509a52514b7d4a09232696a76858fc 348 PANTHER PTHR33169:SF2 1 130 4.0E-37 T 16-09-2016 Spa2297_RS22290 6c509a52514b7d4a09232696a76858fc 348 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 5.2E-22 T 16-09-2016 IPR005149 Transcription regulator PadR, N-terminal Spa2297_RS22290 6c509a52514b7d4a09232696a76858fc 348 PANTHER PTHR33169 1 130 4.0E-37 T 16-09-2016 Spa2297_RS22290 6c509a52514b7d4a09232696a76858fc 348 Gene3D G3DSA:1.10.10.10 4 99 8.4E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22290 6c509a52514b7d4a09232696a76858fc 348 SUPERFAMILY SSF46785 10 118 3.01E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16780 5fc867a03badf1724f9584582af1cafb 431 SMART SM00752 17 361 2.2E-99 T 16-09-2016 IPR011020 HTTM Spa2297_RS16780 5fc867a03badf1724f9584582af1cafb 431 PANTHER PTHR39535 224 375 8.7E-108 T 16-09-2016 Spa2297_RS16780 5fc867a03badf1724f9584582af1cafb 431 PANTHER PTHR39535 2 208 8.7E-108 T 16-09-2016 Spa2297_RS20475 78ad5dad576c4f2a857c9125d332cdb2 466 PANTHER PTHR31302:SF7 184 466 6.1E-94 T 16-09-2016 Spa2297_RS20475 78ad5dad576c4f2a857c9125d332cdb2 466 PANTHER PTHR31302 184 466 6.1E-94 T 16-09-2016 Spa2297_RS20475 78ad5dad576c4f2a857c9125d332cdb2 466 Gene3D G3DSA:3.60.21.10 245 414 5.0E-18 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS20475 78ad5dad576c4f2a857c9125d332cdb2 466 Pfam PF00149 Calcineurin-like phosphoesterase 246 406 1.1E-11 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS20475 78ad5dad576c4f2a857c9125d332cdb2 466 SUPERFAMILY SSF56300 246 462 3.28E-32 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 SUPERFAMILY SSF47413 13 70 6.62E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 PANTHER PTHR30146 11 341 3.8E-146 T 16-09-2016 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 SUPERFAMILY SSF53822 72 340 3.93E-60 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 SMART SM00354 12 82 1.5E-25 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 Gene3D G3DSA:1.10.260.40 15 64 6.1E-24 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 Pfam PF13377 Periplasmic binding protein-like domain 179 337 5.3E-38 T 16-09-2016 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 PANTHER PTHR30146:SF34 11 341 3.8E-146 T 16-09-2016 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 59 2.4E-17 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 Gene3D G3DSA:3.40.50.2300 65 186 1.2E-26 T 16-09-2016 Spa2297_RS01280 37cdf023bd16d07a02354b25bd53dfb8 346 Gene3D G3DSA:3.40.50.2300 187 318 9.8E-46 T 16-09-2016 Spa2297_RS06345 1360c3b1c43b87aa4c229538886b0718 123 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 121 1.3E-30 T 16-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 Spa2297_RS06345 1360c3b1c43b87aa4c229538886b0718 123 SUPERFAMILY SSF54534 16 123 1.18E-40 T 16-09-2016 Spa2297_RS06345 1360c3b1c43b87aa4c229538886b0718 123 Gene3D G3DSA:3.10.50.40 9 123 1.1E-41 T 16-09-2016 Spa2297_RS06345 1360c3b1c43b87aa4c229538886b0718 123 PANTHER PTHR10516 19 123 3.3E-46 T 16-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type Spa2297_RS27830 cda0fac48a9addcd847d24fc09ad44ea 430 SUPERFAMILY SSF50998 49 238 1.18E-8 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS27830 cda0fac48a9addcd847d24fc09ad44ea 430 Pfam PF13360 PQQ-like domain 50 176 3.0E-4 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS06380 0968862c2605bb06c9f8e32c6a9879c4 72 Pfam PF05639 Pup-like protein 4 72 2.5E-30 T 16-09-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 Spa2297_RS06380 0968862c2605bb06c9f8e32c6a9879c4 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.762 T 16-09-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 Spa2297_RS06380 0968862c2605bb06c9f8e32c6a9879c4 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 42 72 1.4E-20 T 16-09-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 Spa2297_RS14335 1daeeb2a6912ba6f1cec4dc7e97965bc 246 SUPERFAMILY SSF53335 9 245 7.02E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS14335 1daeeb2a6912ba6f1cec4dc7e97965bc 246 Gene3D G3DSA:3.40.50.150 179 226 3.5E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS14335 1daeeb2a6912ba6f1cec4dc7e97965bc 246 Gene3D G3DSA:3.40.50.150 5 146 3.5E-26 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS14335 1daeeb2a6912ba6f1cec4dc7e97965bc 246 Pfam PF13649 Methyltransferase domain 45 137 2.5E-10 T 16-09-2016 Spa2297_RS10435 c188d5214d969ce3db912301fd47a6e6 228 Pfam PF02698 DUF218 domain 58 176 8.5E-26 T 16-09-2016 IPR003848 Domain of unknown function DUF218 Spa2297_RS10435 c188d5214d969ce3db912301fd47a6e6 228 PANTHER PTHR30336:SF0 5 214 1.1E-77 T 16-09-2016 Spa2297_RS10435 c188d5214d969ce3db912301fd47a6e6 228 Gene3D G3DSA:3.40.50.620 51 173 1.9E-11 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS10435 c188d5214d969ce3db912301fd47a6e6 228 PANTHER PTHR30336 5 214 1.1E-77 T 16-09-2016 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 SUPERFAMILY SSF53383 31 434 1.71E-72 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 PANTHER PTHR11751:SF410 14 48 3.8E-99 T 16-09-2016 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 PANTHER PTHR11751 64 433 3.8E-99 T 16-09-2016 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 PANTHER PTHR11751 14 48 3.8E-99 T 16-09-2016 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 Pfam PF00155 Aminotransferase class I and II 95 429 3.9E-25 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 Gene3D G3DSA:3.90.1150.10 357 435 4.5E-7 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 PANTHER PTHR11751:SF410 64 433 3.8E-99 T 16-09-2016 Spa2297_RS26660 bcd1a52588f047750e65d5ea6baaa908 444 Gene3D G3DSA:3.40.640.10 82 316 3.5E-64 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS25105 b1a7b841058f5d79ae8fccdf448c5126 428 PANTHER PTHR32468 16 413 2.3E-95 T 16-09-2016 Spa2297_RS25105 b1a7b841058f5d79ae8fccdf448c5126 428 Pfam PF00999 Sodium/hydrogen exchanger family 16 401 1.9E-57 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS25105 b1a7b841058f5d79ae8fccdf448c5126 428 PANTHER PTHR32468:SF0 16 413 2.3E-95 T 16-09-2016 Spa2297_RS30205 432e2c618073de35f13513a90416b182 87 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 5.3E-25 T 16-09-2016 IPR033457 Protein of unknown function DUF5133 Spa2297_RS28745 3a2d062a7319583457044a4241bbf026 400 SUPERFAMILY SSF50969 54 246 3.37E-22 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS28745 3a2d062a7319583457044a4241bbf026 400 SUPERFAMILY SSF50969 276 393 3.37E-22 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS28745 3a2d062a7319583457044a4241bbf026 400 Gene3D G3DSA:2.130.10.10 55 393 1.8E-17 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 SUPERFAMILY SSF81301 554 839 1.14E-59 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 SUPERFAMILY SSF81593 846 996 6.43E-35 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Pfam PF08335 GlnD PII-uridylyltransferase 853 995 1.3E-20 T 16-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Pfam PF08335 GlnD PII-uridylyltransferase 337 477 5.3E-36 T 16-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 SUPERFAMILY SSF81301 60 323 2.98E-67 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 SUPERFAMILY SSF81593 328 478 1.26E-39 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 85 986 17.111 T 16-09-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Gene3D G3DSA:3.30.460.10 682 839 1.9E-49 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Gene3D G3DSA:3.30.460.10 164 324 6.2E-54 T 16-09-2016 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 582 830 1.7E-42 T 16-09-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 89 314 1.9E-46 T 16-09-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Spa2297_RS09340 8b44cd23e8eb20cd02add77748d5f3cc 997 PANTHER PTHR30621 1 997 0.0 T 16-09-2016 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 164 5.5E-14 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 Pfam PF08281 Sigma-70, region 4 116 162 1.4E-7 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 Pfam PF04542 Sigma-70 region 2 12 75 2.5E-13 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 PANTHER PTHR30173 3 288 1.4E-100 T 16-09-2016 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 Gene3D G3DSA:1.10.10.10 113 165 7.8E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 SUPERFAMILY SSF88659 106 164 1.64E-9 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 Gene3D G3DSA:3.10.450.50 172 287 8.0E-11 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 SUPERFAMILY SSF54427 173 286 3.51E-11 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 PANTHER PTHR30173:SF11 3 288 1.4E-100 T 16-09-2016 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 Gene3D G3DSA:1.10.1740.10 12 101 1.0E-13 T 16-09-2016 Spa2297_RS17690 534d0753d5805b521b3e22303fea0d80 296 SUPERFAMILY SSF88946 12 87 4.71E-14 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 Gene3D G3DSA:1.10.443.10 144 325 4.5E-31 T 16-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 PANTHER PTHR30349:SF20 41 347 2.9E-31 T 16-09-2016 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 Pfam PF00589 Phage integrase family 148 319 5.2E-11 T 16-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 SUPERFAMILY SSF56349 39 326 9.42E-52 T 16-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 PANTHER PTHR30349 41 347 2.9E-31 T 16-09-2016 Spa2297_RS17435 6ba12fe5d17ac09803b181ea187365ea 357 Gene3D G3DSA:1.10.150.130 39 133 2.9E-10 T 16-09-2016 IPR023109 Integrase/recombinase, N-terminal Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 PIRSF PIRSF000388 23 291 3.3E-109 T 16-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 SUPERFAMILY SSF51621 29 289 5.1E-101 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 Pfam PF02548 Ketopantoate hydroxymethyltransferase 29 285 8.0E-109 T 16-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 PANTHER PTHR20881 28 289 1.2E-146 T 16-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 30 290 42.312 T 16-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 Gene3D G3DSA:3.20.20.60 28 290 2.4E-112 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS09410 6ab915ece341c9d89fdd29a429b65f0b 291 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 34 291 6.4E-94 T 16-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 Spa2297_RS28180 934473c2657a0b1031962c88183ea026 213 Gene3D G3DSA:3.40.50.1580 31 177 3.8E-20 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS28180 934473c2657a0b1031962c88183ea026 213 SUPERFAMILY SSF53167 25 177 2.75E-25 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS28180 934473c2657a0b1031962c88183ea026 213 Pfam PF01048 Phosphorylase superfamily 31 173 3.4E-16 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS29650 67b4b1fc58b1f201bb9847a5847b2498 386 Pfam PF06134 L-rhamnose isomerase (RhaA) 95 335 1.2E-5 T 16-09-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 Spa2297_RS29650 67b4b1fc58b1f201bb9847a5847b2498 386 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 5 376 1.6E-198 T 16-09-2016 IPR013457 Rhamnose isomerase-related Spa2297_RS29650 67b4b1fc58b1f201bb9847a5847b2498 386 Gene3D G3DSA:3.20.20.150 16 372 3.4E-89 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS29650 67b4b1fc58b1f201bb9847a5847b2498 386 SUPERFAMILY SSF51658 25 358 2.05E-96 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS29650 67b4b1fc58b1f201bb9847a5847b2498 386 PANTHER PTHR30268 2 378 5.8E-196 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PANTHER PTHR23501 1 553 0.0 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PANTHER PTHR23501:SF75 1 553 0.0 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 SUPERFAMILY SSF103473 260 432 3.66E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 SUPERFAMILY SSF103473 12 205 3.66E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 SUPERFAMILY SSF103473 482 507 3.66E-69 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PRINTS PR01036 Tetracycline resistance protein TetB signature 214 232 3.7E-8 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 3.7E-8 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 3.7E-8 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 3.7E-8 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 3.7E-8 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 Gene3D G3DSA:1.20.1250.20 21 200 1.5E-32 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 Gene3D G3DSA:1.20.1250.20 484 514 5.9E-19 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 Gene3D G3DSA:1.20.1250.20 276 434 5.9E-19 T 16-09-2016 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 440 9.0E-76 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS28410 8468bbb794187b15c125e1716c153a5e 706 Pfam PF07690 Major Facilitator Superfamily 30 422 5.9E-46 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 PANTHER PTHR23026 11 194 1.1E-101 T 16-09-2016 Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 PANTHER PTHR23026:SF110 11 194 1.1E-101 T 16-09-2016 Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 Gene3D G3DSA:3.40.109.10 13 194 3.1E-37 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 Pfam PF00881 Nitroreductase family 15 173 1.4E-15 T 16-09-2016 IPR029479 Nitroreductase Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 196 40.611 T 16-09-2016 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 Spa2297_RS21380 e2e13f8251122566d1a651da25cc73ba 196 SUPERFAMILY SSF55469 14 194 3.93E-38 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS30180 abf2948dd07f261ba050e025abb926fa 272 SUPERFAMILY SSF53335 16 263 3.65E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30180 abf2948dd07f261ba050e025abb926fa 272 Gene3D G3DSA:3.40.50.150 1 270 2.2E-104 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30180 abf2948dd07f261ba050e025abb926fa 272 Pfam PF04672 S-adenosyl methyltransferase 5 271 9.9E-108 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS30180 abf2948dd07f261ba050e025abb926fa 272 PIRSF PIRSF017393 1 272 4.6E-94 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 2.2E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 Gene3D G3DSA:1.10.357.10 3 137 4.5E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 PANTHER PTHR30328 3 104 2.0E-27 T 16-09-2016 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 SUPERFAMILY SSF46689 3 77 3.69E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.9E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS19575 5704626919dc88f93c43ab09c04b7cb4 190 PANTHER PTHR30328:SF12 3 104 2.0E-27 T 16-09-2016 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 Gene3D G3DSA:1.10.10.10 2 87 2.4E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 PANTHER PTHR30346:SF2 2 304 1.2E-122 T 16-09-2016 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 Gene3D G3DSA:3.40.190.10 183 270 1.7E-22 T 16-09-2016 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 Gene3D G3DSA:3.40.190.10 91 182 5.8E-15 T 16-09-2016 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 SUPERFAMILY SSF46785 2 112 7.15E-21 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 Pfam PF03466 LysR substrate binding domain 88 296 5.2E-39 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 SUPERFAMILY SSF53850 90 298 2.95E-35 T 16-09-2016 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.9E-16 T 16-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spa2297_RS11655 aae3701e227f2fde13734377edba1b8e 305 PANTHER PTHR30346 2 304 1.2E-122 T 16-09-2016 Spa2297_RS14270 6c4956477036fa00898ca76a725515a0 371 Pfam PF03747 ADP-ribosylglycohydrolase 23 325 1.5E-50 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS14270 6c4956477036fa00898ca76a725515a0 371 PANTHER PTHR16222 9 369 3.2E-86 T 16-09-2016 Spa2297_RS14270 6c4956477036fa00898ca76a725515a0 371 SUPERFAMILY SSF101478 159 346 3.27E-53 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS14270 6c4956477036fa00898ca76a725515a0 371 SUPERFAMILY SSF101478 16 131 3.27E-53 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS14270 6c4956477036fa00898ca76a725515a0 371 PANTHER PTHR16222:SF12 9 369 3.2E-86 T 16-09-2016 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 Pfam PF01261 Xylose isomerase-like TIM barrel 41 265 1.1E-25 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 Gene3D G3DSA:3.20.20.150 4 386 4.8E-137 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 384 1.5E-218 T 16-09-2016 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 45 67 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 129 150 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 105 124 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 248 259 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 281 292 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 220 247 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 82 102 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 156 175 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PRINTS PR00688 Xylose isomerase signature 178 202 1.0E-74 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 Hamap MF_00455 Xylose isomerase [xylA]. 1 383 37.971 T 16-09-2016 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 SUPERFAMILY SSF51658 1 386 2.75E-114 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS04205 e537197821a7a0982f18d968c6e587a0 387 PANTHER PTHR32176 1 332 7.6E-97 T 16-09-2016 Spa2297_RS25610 cd0a6576120221ae4f0e64794a562410 732 SUPERFAMILY SSF48576 375 706 9.78E-64 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS25610 cd0a6576120221ae4f0e64794a562410 732 Gene3D G3DSA:1.10.600.10 3 328 1.2E-105 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS25610 cd0a6576120221ae4f0e64794a562410 732 Gene3D G3DSA:1.10.600.10 366 697 5.9E-94 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS25610 cd0a6576120221ae4f0e64794a562410 732 SUPERFAMILY SSF48576 4 332 3.74E-66 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PANTHER PTHR10804 1 256 7.5E-103 T 16-09-2016 Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 Gene3D G3DSA:3.90.230.10 3 258 3.9E-76 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PANTHER PTHR10804:SF41 1 256 7.5E-103 T 16-09-2016 Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 Pfam PF00557 Metallopeptidase family M24 11 249 4.2E-42 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 SUPERFAMILY SSF55920 3 257 2.75E-74 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 7.8E-22 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 7.8E-22 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 7.8E-22 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 7.8E-22 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.828 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS19905 db95be8115c8184c4a24a494c7f62f14 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 257 3.4E-81 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS06055 935fd45c3125daa5cb2661bbc1bd4b66 245 Pfam PF02424 ApbE family 1 80 3.7E-8 T 16-09-2016 IPR024932 Flavin transferase ApbE GO:0017013 Spa2297_RS06055 935fd45c3125daa5cb2661bbc1bd4b66 245 Pfam PF02424 ApbE family 86 225 3.2E-35 T 16-09-2016 IPR024932 Flavin transferase ApbE GO:0017013 Spa2297_RS06055 935fd45c3125daa5cb2661bbc1bd4b66 245 SUPERFAMILY SSF143631 1 243 1.83E-57 T 16-09-2016 IPR003374 ApbE-like domain Spa2297_RS06055 935fd45c3125daa5cb2661bbc1bd4b66 245 PANTHER PTHR30040 1 244 4.8E-66 T 16-09-2016 Spa2297_RS26080 cd68de643c03eaeec9aff2178dbbcd71 327 Gene3D G3DSA:1.10.10.10 268 323 2.3E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26080 cd68de643c03eaeec9aff2178dbbcd71 327 SUPERFAMILY SSF46894 267 323 3.74E-9 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26080 cd68de643c03eaeec9aff2178dbbcd71 327 SMART SM00421 260 317 2.4E-8 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26080 cd68de643c03eaeec9aff2178dbbcd71 327 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 68 1.2E-6 T 16-09-2016 IPR002831 Transcription regulator TrmB, N-terminal Spa2297_RS26080 cd68de643c03eaeec9aff2178dbbcd71 327 Gene3D G3DSA:1.10.10.10 1 68 1.0E-4 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 Gene3D G3DSA:1.10.1660.10 3 111 1.6E-20 T 16-09-2016 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 SUPERFAMILY SSF55979 126 248 2.59E-15 T 16-09-2016 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 SMART SM00480 48 358 2.2E-4 T 16-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.4E-12 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 SUPERFAMILY SSF46955 3 96 4.76E-20 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 SUPERFAMILY SSF55979 308 362 3.58E-7 T 16-09-2016 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 245 2.2E-15 T 16-09-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 Gene3D G3DSA:3.10.150.10 308 362 2.0E-8 T 16-09-2016 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 Gene3D G3DSA:3.10.150.10 124 249 9.3E-25 T 16-09-2016 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 SMART SM00422 3 72 1.3E-10 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS04250 4df0db20ed446f4aac9d59ec255e0cde 364 PANTHER PTHR30478 78 364 2.6E-58 T 16-09-2016 Spa2297_RS17615 2c65c8c2ef3297b627d3f46c772a0e89 330 SUPERFAMILY SSF53474 184 253 2.22E-5 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17615 2c65c8c2ef3297b627d3f46c772a0e89 330 Gene3D G3DSA:3.40.50.1820 160 256 8.5E-6 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17615 2c65c8c2ef3297b627d3f46c772a0e89 330 Pfam PF06259 Alpha/beta hydrolase 102 271 2.1E-52 T 16-09-2016 IPR010427 Protein of unknown function DUF1023 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 SUPERFAMILY SSF54631 195 337 1.19E-34 T 16-09-2016 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Pfam PF01595 Domain of unknown function DUF21 9 185 3.9E-30 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 SMART SM01091 337 423 4.3E-15 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Pfam PF00571 CBS domain 200 255 1.3E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Pfam PF00571 CBS domain 274 322 3.5E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 PANTHER PTHR22777 5 431 1.2E-221 T 16-09-2016 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 SMART SM00116 209 258 6.8E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 SMART SM00116 274 322 2.3 T 16-09-2016 IPR000644 CBS domain Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Gene3D G3DSA:3.30.465.10 330 418 2.7E-19 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Gene3D G3DSA:3.10.580.10 186 329 2.3E-22 T 16-09-2016 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 PANTHER PTHR22777:SF17 5 431 1.2E-221 T 16-09-2016 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 SUPERFAMILY SSF56176 336 419 1.74E-11 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS10675 bdf1f734719672a2a6756ff390ecaf36 434 Pfam PF03471 Transporter associated domain 338 421 4.4E-13 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 49 87 1.4E-9 T 16-09-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 PANTHER PTHR30465 42 326 5.0E-204 T 16-09-2016 Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 326 1.8E-26 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 PANTHER PTHR30465:SF29 42 326 5.0E-204 T 16-09-2016 Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 SUPERFAMILY SSF161098 121 311 2.75E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21595 49414d115dbe55c5129333cb4a8c74d3 326 Gene3D G3DSA:1.10.3720.10 119 323 3.7E-24 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 157 1.6E-26 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 PANTHER PTHR12993:SF13 5 290 1.2E-85 T 16-09-2016 Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 PANTHER PTHR12993 5 290 1.2E-85 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 SUPERFAMILY SSF102588 7 284 2.88E-65 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 284 39.698 T 16-09-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 Gene3D G3DSA:3.40.50.10320 6 286 2.5E-84 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS21620 16e404ab16b8b4d3c65ae42fdb199e18 290 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 284 2.6E-120 T 16-09-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 SUPERFAMILY SSF51283 2 183 8.37E-57 T 16-09-2016 IPR029054 dUTPase-like Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 Pfam PF00692 dUTPase 70 178 7.8E-10 T 16-09-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 5.7E-65 T 16-09-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 PANTHER PTHR11241 2 186 1.1E-67 T 16-09-2016 Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.649 T 16-09-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 Gene3D G3DSA:2.70.40.10 2 183 1.2E-67 T 16-09-2016 IPR029054 dUTPase-like Spa2297_RS17445 2a30f2c13f153550aee2eea6f81c0c7d 191 PANTHER PTHR11241:SF7 2 186 1.1E-67 T 16-09-2016 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 SMART SM00220 15 275 1.7E-42 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 Pfam PF00069 Protein kinase domain 15 267 6.1E-39 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 Gene3D G3DSA:1.10.510.10 98 267 1.5E-40 T 16-09-2016 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 Gene3D G3DSA:3.30.200.20 9 70 3.4E-13 T 16-09-2016 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 SUPERFAMILY SSF56112 11 272 8.77E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 SUPERFAMILY SSF56112 339 375 8.77E-61 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 PANTHER PTHR24362:SF247 8 309 1.2E-110 T 16-09-2016 Spa2297_RS17710 e5fe008d048f13349b9fb90bd04a7e48 578 PANTHER PTHR24362 8 309 1.2E-110 T 16-09-2016 Spa2297_RS25445 9c741abff4b20a8d230ff6f140e293c3 241 Gene3D G3DSA:3.40.1490.10 149 237 1.4E-15 T 16-09-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 Spa2297_RS25445 9c741abff4b20a8d230ff6f140e293c3 241 PANTHER PTHR12649 110 237 1.9E-21 T 16-09-2016 Spa2297_RS25445 9c741abff4b20a8d230ff6f140e293c3 241 SUPERFAMILY SSF102462 149 237 1.36E-19 T 16-09-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 Spa2297_RS25445 9c741abff4b20a8d230ff6f140e293c3 241 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 151 237 2.3E-6 T 16-09-2016 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 SMART SM00382 57 251 2.9E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 SUPERFAMILY SSF52540 28 252 9.61E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 Gene3D G3DSA:3.40.50.300 30 252 7.7E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 Pfam PF00005 ABC transporter 48 202 1.6E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 PANTHER PTHR24220 30 251 3.8E-79 T 16-09-2016 Spa2297_RS11340 33fe3cfc09cc3fbd80e6307c1818d383 320 PANTHER PTHR24220:SF86 30 251 3.8E-79 T 16-09-2016 Spa2297_RS14315 1463191388e83962af98d929b3ea9e2c 261 PANTHER PTHR14859 1 181 9.8E-26 T 16-09-2016 IPR027317 PGAP2-interacting protein Spa2297_RS14315 1463191388e83962af98d929b3ea9e2c 261 Gene3D G3DSA:3.60.10.10 1 260 5.4E-23 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS14315 1463191388e83962af98d929b3ea9e2c 261 SUPERFAMILY SSF56219 1 260 2.49E-42 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS14315 1463191388e83962af98d929b3ea9e2c 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 252 5.5E-22 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS20625 fd472a9b47f4887e02dfb06716909206 738 Pfam PF04230 Polysaccharide pyruvyl transferase 439 665 8.1E-10 T 16-09-2016 IPR007345 Polysaccharide pyruvyl transferase Spa2297_RS20625 fd472a9b47f4887e02dfb06716909206 738 SUPERFAMILY SSF53448 21 122 5.34E-5 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20625 fd472a9b47f4887e02dfb06716909206 738 SUPERFAMILY SSF48452 256 361 4.69E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS20625 fd472a9b47f4887e02dfb06716909206 738 Pfam PF13432 Tetratricopeptide repeat 259 317 2.1E-8 T 16-09-2016 Spa2297_RS20625 fd472a9b47f4887e02dfb06716909206 738 Gene3D G3DSA:1.25.40.10 255 360 5.8E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00420 d2f12e3c61c5092b9f5f6020134fff15 351 Pfam PF13556 PucR C-terminal helix-turn-helix domain 282 337 1.1E-13 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS00420 d2f12e3c61c5092b9f5f6020134fff15 351 PANTHER PTHR33744:SF4 72 350 1.3E-47 T 16-09-2016 Spa2297_RS00420 d2f12e3c61c5092b9f5f6020134fff15 351 PANTHER PTHR33744 72 350 1.3E-47 T 16-09-2016 Spa2297_RS03880 10540426efdcbd57d1733d7d346a0fec 122 SUPERFAMILY SSF52821 2 113 1.07E-30 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03880 10540426efdcbd57d1733d7d346a0fec 122 Pfam PF00581 Rhodanese-like domain 27 106 2.0E-12 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03880 10540426efdcbd57d1733d7d346a0fec 122 SMART SM00450 12 110 6.0E-21 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS03880 10540426efdcbd57d1733d7d346a0fec 122 Gene3D G3DSA:3.40.250.10 7 112 1.0E-28 T 16-09-2016 IPR001763 Rhodanese-like domain Spa2297_RS12000 bc1e0edc0ba23ce43a5ace5978778db1 321 PANTHER PTHR34580 1 317 4.8E-23 T 16-09-2016 Spa2297_RS12000 bc1e0edc0ba23ce43a5ace5978778db1 321 Pfam PF13280 WYL domain 150 316 4.5E-24 T 16-09-2016 IPR026881 WYL domain Spa2297_RS12000 bc1e0edc0ba23ce43a5ace5978778db1 321 Gene3D G3DSA:1.10.10.10 1 62 9.8E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12000 bc1e0edc0ba23ce43a5ace5978778db1 321 SUPERFAMILY SSF46785 1 57 3.38E-10 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12000 bc1e0edc0ba23ce43a5ace5978778db1 321 Pfam PF08279 HTH domain 6 58 8.0E-11 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS09765 6f4661b07bd765f2e54deb492d4e1b9f 130 Gene3D G3DSA:2.60.200.20 24 71 3.5E-4 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS09765 6f4661b07bd765f2e54deb492d4e1b9f 130 SUPERFAMILY SSF49879 30 89 2.49E-6 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 PANTHER PTHR21340 120 153 1.1E-72 T 16-09-2016 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 PANTHER PTHR21340:SF1 2 103 1.1E-72 T 16-09-2016 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 16-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 PANTHER PTHR21340 2 103 1.1E-72 T 16-09-2016 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 Pfam PF00293 NUDIX domain 3 147 8.0E-13 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 SUPERFAMILY SSF55811 2 149 1.21E-18 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 Gene3D G3DSA:3.90.79.10 2 148 8.3E-25 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS04345 c5f247c15c145499497a1f37fbf7c6cb 153 PANTHER PTHR21340:SF1 120 153 1.1E-72 T 16-09-2016 Spa2297_RS13990 18385d87f151f164724b879df2e90422 143 Pfam PF04255 Protein of unknown function (DUF433) 79 131 3.2E-10 T 16-09-2016 IPR007367 Protein of unknown function DUF433 Spa2297_RS13990 18385d87f151f164724b879df2e90422 143 Gene3D G3DSA:1.10.10.10 78 133 2.8E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13990 18385d87f151f164724b879df2e90422 143 SUPERFAMILY SSF46689 54 135 6.09E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30430 734be59e9604ee521f368361e3b01ccc 105 Pfam PF05800 Gas vesicle synthesis protein GvpO 13 104 9.0E-34 T 16-09-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 Spa2297_RS30430 734be59e9604ee521f368361e3b01ccc 105 PIRSF PIRSF028743 1 105 1.6E-38 T 16-09-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 SMART SM00829 11 338 3.5E-8 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 PANTHER PTHR11695:SF498 16 339 2.0E-119 T 16-09-2016 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 Pfam PF00107 Zinc-binding dehydrogenase 179 302 7.4E-24 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 SUPERFAMILY SSF51735 143 308 1.09E-37 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 Gene3D G3DSA:3.40.50.720 173 287 2.8E-26 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 SUPERFAMILY SSF50129 1 174 1.16E-47 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 Gene3D G3DSA:3.90.180.10 2 172 7.2E-57 T 16-09-2016 IPR011032 GroES-like Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 136 7.1E-28 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS10985 82376a06e148f30c5db82f1907b8133c 341 PANTHER PTHR11695 16 339 2.0E-119 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS08655 bcc7d32b48111fcaec389e6a25027ba6 265 Hamap MF_00443 Thiazole synthase [thiG]. 5 256 42.327 T 16-09-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 Spa2297_RS08655 bcc7d32b48111fcaec389e6a25027ba6 265 PANTHER PTHR34266 1 261 1.2E-153 T 16-09-2016 Spa2297_RS08655 bcc7d32b48111fcaec389e6a25027ba6 265 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 7.5E-106 T 16-09-2016 Spa2297_RS08655 bcc7d32b48111fcaec389e6a25027ba6 265 Gene3D G3DSA:3.20.20.70 7 251 2.2E-56 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS08655 bcc7d32b48111fcaec389e6a25027ba6 265 SUPERFAMILY SSF110399 4 242 9.55E-81 T 16-09-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 Spa2297_RS02790 9f6633f7d042b3cc60df7ca61ff77217 128 SUPERFAMILY SSF55961 11 127 9.4E-19 T 16-09-2016 Spa2297_RS02790 9f6633f7d042b3cc60df7ca61ff77217 128 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 125 2.8E-10 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS02790 9f6633f7d042b3cc60df7ca61ff77217 128 Gene3D G3DSA:3.30.530.20 12 97 3.8E-7 T 16-09-2016 IPR023393 START-like domain Spa2297_RS19245 477f7b4f8705574f81ebd98016c39be7 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.809 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS19245 477f7b4f8705574f81ebd98016c39be7 99 PANTHER PTHR11434:SF0 2 98 2.4E-35 T 16-09-2016 Spa2297_RS19245 477f7b4f8705574f81ebd98016c39be7 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 4.4E-24 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS19245 477f7b4f8705574f81ebd98016c39be7 99 PANTHER PTHR11434 2 98 2.4E-35 T 16-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 SUPERFAMILY SSF46689 21 99 1.23E-20 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 5.3E-16 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 3.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 3.0E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 PANTHER PTHR30328 7 225 2.1E-108 T 16-09-2016 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 Gene3D G3DSA:1.10.357.10 17 210 1.4E-46 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 PANTHER PTHR30328:SF12 7 225 2.1E-108 T 16-09-2016 Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 47 77 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS13585 9032d3ddf8428aefb50ab3565547f019 225 SUPERFAMILY SSF48498 102 212 1.27E-7 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 SUPERFAMILY SSF47413 2 60 1.18E-15 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 Gene3D G3DSA:3.40.50.2300 189 324 6.0E-55 T 16-09-2016 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 PANTHER PTHR30146 1 347 1.6E-124 T 16-09-2016 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 PANTHER PTHR30146:SF48 1 347 1.6E-124 T 16-09-2016 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 SUPERFAMILY SSF53822 62 345 2.36E-62 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 Pfam PF13377 Periplasmic binding protein-like domain 184 343 1.6E-32 T 16-09-2016 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 SMART SM00354 2 72 4.4E-24 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 Gene3D G3DSA:1.10.260.40 3 62 7.9E-21 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.1E-17 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 Gene3D G3DSA:3.40.50.2300 63 188 1.2E-43 T 16-09-2016 Spa2297_RS11640 aec1b13185a8c0ad25612d6988fdab77 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS02525 381d1b1b89fb91cbd31899ca59182a6d 337 PANTHER PTHR30238 3 314 1.8E-139 T 16-09-2016 Spa2297_RS02525 381d1b1b89fb91cbd31899ca59182a6d 337 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 308 5.2E-116 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS02525 381d1b1b89fb91cbd31899ca59182a6d 337 PANTHER PTHR30238:SF0 3 314 1.8E-139 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS02525 381d1b1b89fb91cbd31899ca59182a6d 337 Pfam PF03741 Integral membrane protein TerC family 70 272 1.7E-52 T 16-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 Spa2297_RS17270 ec67cfb42214b93ed72eab13d70f5671 257 SUPERFAMILY SSF88713 67 252 2.15E-50 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS17270 ec67cfb42214b93ed72eab13d70f5671 257 Pfam PF01522 Polysaccharide deacetylase 67 189 1.9E-26 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS17270 ec67cfb42214b93ed72eab13d70f5671 257 PANTHER PTHR10587 70 253 2.6E-48 T 16-09-2016 Spa2297_RS17270 ec67cfb42214b93ed72eab13d70f5671 257 Gene3D G3DSA:3.20.20.370 66 252 5.0E-52 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 Gene3D G3DSA:3.40.640.10 63 279 1.8E-89 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 PANTHER PTHR13693:SF60 1 395 1.2E-249 T 16-09-2016 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 16-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 396 54.22 T 16-09-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 PANTHER PTHR13693 1 395 1.2E-249 T 16-09-2016 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 395 2.3E-192 T 16-09-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 SUPERFAMILY SSF53383 7 394 4.39E-117 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 Gene3D G3DSA:3.90.1150.10 280 393 1.6E-29 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS28325 17e34b6a59f1e096c28641788d1708ec 397 Pfam PF00155 Aminotransferase class I and II 46 388 8.5E-71 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS26390 75bc5b15512255990dce5a99158af41a 515 PANTHER PTHR34384 1 513 1.7E-195 T 16-09-2016 Spa2297_RS26390 75bc5b15512255990dce5a99158af41a 515 Pfam PF06276 Ferric iron reductase FhuF-like transporter 368 501 4.3E-21 T 16-09-2016 IPR022770 Ferric iron reductase FhuF domain Spa2297_RS26390 75bc5b15512255990dce5a99158af41a 515 PANTHER PTHR34384:SF1 1 513 1.7E-195 T 16-09-2016 Spa2297_RS26390 75bc5b15512255990dce5a99158af41a 515 Pfam PF04183 IucA / IucC family 140 352 2.2E-31 T 16-09-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 Pfam PF04203 Sortase family 101 238 6.2E-22 T 16-09-2016 IPR005754 Sortase family Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 PANTHER PTHR33393:SF3 2 249 1.1E-75 T 16-09-2016 Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 SUPERFAMILY SSF63817 93 241 2.09E-26 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 PANTHER PTHR33393 2 249 1.1E-75 T 16-09-2016 Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 Gene3D G3DSA:2.40.260.10 96 241 5.5E-22 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS16715 d18d451c9d9223b81a49c72e8d174eec 254 TIGRFAM TIGR01076 sortase_fam: sortase 101 239 3.1E-12 T 16-09-2016 IPR005754 Sortase family Spa2297_RS15700 5739aeaa21e4179c36b95af58de6d2d3 116 Pfam PF06262 Zinicin-like metallopeptidase 28 114 2.7E-34 T 16-09-2016 IPR010428 Zinicin-like metallopeptidase Spa2297_RS15700 5739aeaa21e4179c36b95af58de6d2d3 116 SUPERFAMILY SSF55486 2 115 3.18E-40 T 16-09-2016 Spa2297_RS15700 5739aeaa21e4179c36b95af58de6d2d3 116 PANTHER PTHR41522 1 116 1.8E-53 T 16-09-2016 Spa2297_RS15700 5739aeaa21e4179c36b95af58de6d2d3 116 Gene3D G3DSA:3.40.390.10 13 112 7.7E-4 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 Pfam PF07690 Major Facilitator Superfamily 234 398 3.2E-15 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 PANTHER PTHR23542:SF1 2 418 1.9E-156 T 16-09-2016 Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 SUPERFAMILY SSF103473 17 393 8.76E-34 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 PANTHER PTHR23542 2 418 1.9E-156 T 16-09-2016 Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 Gene3D G3DSA:1.20.1250.20 18 188 3.1E-6 T 16-09-2016 Spa2297_RS24815 7778dc5ed35745a90f0255f4ff0818b6 418 Gene3D G3DSA:1.20.1250.20 216 395 4.4E-19 T 16-09-2016 Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 Pfam PF05593 RHS Repeat 289 321 6.6E-5 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 Pfam PF05593 RHS Repeat 652 689 1.5E-5 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 Pfam PF05593 RHS Repeat 591 625 2.5E-6 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 Pfam PF05593 RHS Repeat 632 667 2.6E-7 T 16-09-2016 IPR031325 RHS repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 928 1000 1.0E-24 T 16-09-2016 IPR022385 Rhs repeat-associated core GO:0097264 Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 611 648 5.6E-4 T 16-09-2016 IPR006530 YD repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 652 691 3.7E-6 T 16-09-2016 IPR006530 YD repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 292 325 1.3E-4 T 16-09-2016 IPR006530 YD repeat Spa2297_RS14255 4ea5df303c2b07bf7c67891b705cec34 1102 PANTHER PTHR11219 895 1003 2.8E-27 T 16-09-2016 Spa2297_RS25885 4b89a6d0972ebd47f320088b4b11d6e1 112 SUPERFAMILY SSF52091 19 110 7.85E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS25885 4b89a6d0972ebd47f320088b4b11d6e1 112 Pfam PF13466 STAS domain 26 105 2.5E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS25885 4b89a6d0972ebd47f320088b4b11d6e1 112 Gene3D G3DSA:3.30.750.24 21 109 2.2E-9 T 16-09-2016 IPR002645 STAS domain Spa2297_RS16700 d275619eb442981e57af0cfcfb4fc403 259 Pfam PF05949 Bacterial protein of unknown function (DUF881) 101 255 5.1E-42 T 16-09-2016 IPR010273 Protein of unknown function DUF881 Spa2297_RS16700 d275619eb442981e57af0cfcfb4fc403 259 PANTHER PTHR37313 18 259 1.2E-94 T 16-09-2016 Spa2297_RS16700 d275619eb442981e57af0cfcfb4fc403 259 PANTHER PTHR37313:SF2 18 259 1.2E-94 T 16-09-2016 Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 SUPERFAMILY SSF51735 12 252 5.18E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.3E-9 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PANTHER PTHR24322:SF330 159 191 6.6E-61 T 16-09-2016 Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 Gene3D G3DSA:3.40.50.720 8 253 1.5E-85 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.5E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 1.4E-69 T 16-09-2016 Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PANTHER PTHR24322 159 191 6.6E-61 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PANTHER PTHR24322 17 142 6.6E-61 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06210 9615e462c37d7c6da2c51cabacf0429f 260 PANTHER PTHR24322:SF330 17 142 6.6E-61 T 16-09-2016 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 SUPERFAMILY SSF52374 1 300 1.57E-96 T 16-09-2016 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Gene3D G3DSA:3.90.800.10 52 175 6.0E-41 T 16-09-2016 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PANTHER PTHR11451:SF41 1 320 9.6E-90 T 16-09-2016 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 1 304 1.6E-81 T 16-09-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Gene3D G3DSA:3.40.50.620 177 231 3.9E-34 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Gene3D G3DSA:3.40.50.620 1 51 3.9E-34 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Gene3D G3DSA:1.10.1160.10 234 316 2.8E-30 T 16-09-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PANTHER PTHR11451 1 320 9.6E-90 T 16-09-2016 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 1 467 28.793 T 16-09-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 1 465 1.9E-135 T 16-09-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 SUPERFAMILY SSF48163 301 467 1.96E-35 T 16-09-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 15 5.4E-15 T 16-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 175 185 5.4E-15 T 16-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 32 5.4E-15 T 16-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 199 5.4E-15 T 16-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 Spa2297_RS23505 52b30dbd5a0138b5cd77104b0d02def0 472 Gene3D G3DSA:1.10.10.350 372 467 1.0E-21 T 16-09-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 Spa2297_RS26765 b390b1d0248f93d0476f387042f04a7f 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 1.1E-64 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS26765 b390b1d0248f93d0476f387042f04a7f 280 SUPERFAMILY SSF56317 3 277 5.49E-76 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS26765 b390b1d0248f93d0476f387042f04a7f 280 PANTHER PTHR23088 1 280 4.1E-128 T 16-09-2016 Spa2297_RS26765 b390b1d0248f93d0476f387042f04a7f 280 Gene3D G3DSA:3.60.110.10 3 278 3.5E-85 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS26765 b390b1d0248f93d0476f387042f04a7f 280 PANTHER PTHR23088:SF11 1 280 4.1E-128 T 16-09-2016 Spa2297_RS32130 41e60daaa8f5dffe710b80ac62dfaf69 292 SUPERFAMILY SSF56529 64 283 3.01E-73 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS32130 41e60daaa8f5dffe710b80ac62dfaf69 292 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 279 3.9E-69 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS32130 41e60daaa8f5dffe710b80ac62dfaf69 292 PANTHER PTHR11820 1 292 4.8E-160 T 16-09-2016 Spa2297_RS32130 41e60daaa8f5dffe710b80ac62dfaf69 292 PANTHER PTHR11820:SF71 1 292 4.8E-160 T 16-09-2016 Spa2297_RS32130 41e60daaa8f5dffe710b80ac62dfaf69 292 Gene3D G3DSA:3.90.850.10 67 285 3.8E-85 T 16-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 Gene3D G3DSA:3.40.140.10 1 136 2.4E-36 T 16-09-2016 Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 PANTHER PTHR34858 1 110 8.3E-40 T 16-09-2016 Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 PANTHER PTHR34858:SF1 1 110 8.3E-40 T 16-09-2016 Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 112 4.7E-27 T 16-09-2016 IPR028090 JAB domain, prokaryotic Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 SMART SM00232 1 134 1.4E-24 T 16-09-2016 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 Spa2297_RS12460 4f296ca5093403df081db3b7d7f81890 140 SUPERFAMILY SSF102712 1 133 3.53E-27 T 16-09-2016 Spa2297_RS02310 a4eaf9423fa2ca67a02a81695ebd4308 139 Gene3D G3DSA:2.30.30.240 82 131 3.3E-4 T 16-09-2016 Spa2297_RS02310 a4eaf9423fa2ca67a02a81695ebd4308 139 Pfam PF05239 PRC-barrel domain 80 120 1.3E-4 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS02310 a4eaf9423fa2ca67a02a81695ebd4308 139 SUPERFAMILY SSF50346 81 123 4.45E-5 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 Gene3D G3DSA:2.30.40.10 462 517 9.6E-8 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 PANTHER PTHR22642:SF2 6 518 4.2E-112 T 16-09-2016 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 Gene3D G3DSA:3.20.20.140 179 461 1.5E-33 T 16-09-2016 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 PANTHER PTHR22642 6 518 4.2E-112 T 16-09-2016 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 Pfam PF07969 Amidohydrolase family 45 519 4.8E-80 T 16-09-2016 IPR013108 Amidohydrolase 3 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 SUPERFAMILY SSF51556 56 90 1.6E-28 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 SUPERFAMILY SSF51556 172 481 1.6E-28 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 SUPERFAMILY SSF51338 4 57 5.91E-19 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 SUPERFAMILY SSF51338 480 519 5.91E-19 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31120 0bbc171b0dfa87b9ec3477e8fc109216 525 Gene3D G3DSA:2.30.40.10 6 102 1.1E-15 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 348 3.7E-19 T 16-09-2016 IPR003395 RecF/RecN/SMC, N-terminal Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 PANTHER PTHR32182:SF0 1 362 8.4E-71 T 16-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 ProSitePatterns PS00618 RecF protein signature 2. 316 334 - T 16-09-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 Gene3D G3DSA:3.40.50.300 245 348 1.8E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 Gene3D G3DSA:3.40.50.300 1 167 1.8E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 PANTHER PTHR32182 1 362 8.4E-71 T 16-09-2016 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 365 5.6E-130 T 16-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 16-09-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 373 98.271 T 16-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Spa2297_RS16585 bc9a8c42f450074bea0ca24cce227264 373 SUPERFAMILY SSF52540 1 348 1.1E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15260 7247abd6c179a4d1bed105bbf3473ff0 343 Pfam PF06089 L-asparaginase II 37 340 1.7E-114 T 16-09-2016 IPR010349 L-asparaginase II Spa2297_RS15260 7247abd6c179a4d1bed105bbf3473ff0 343 PANTHER PTHR42110:SF1 1 343 7.2E-94 T 16-09-2016 Spa2297_RS15260 7247abd6c179a4d1bed105bbf3473ff0 343 PANTHER PTHR42110 1 343 7.2E-94 T 16-09-2016 Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 Gene3D G3DSA:1.20.1250.20 29 208 5.4E-27 T 16-09-2016 Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 Gene3D G3DSA:1.20.1250.20 245 422 6.8E-13 T 16-09-2016 Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 PANTHER PTHR11662 39 423 2.9E-106 T 16-09-2016 Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 PANTHER PTHR11662:SF277 39 423 2.9E-106 T 16-09-2016 Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 SUPERFAMILY SSF103473 14 422 1.11E-57 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS16910 2eb5c4e6d597047b8f74c7bebc90c1ce 436 Pfam PF07690 Major Facilitator Superfamily 31 374 1.9E-33 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 11 109 2.6E-29 T 16-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 PANTHER PTHR21043 6 123 2.6E-33 T 16-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 SUPERFAMILY SSF81301 7 118 8.5E-35 T 16-09-2016 Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 Gene3D G3DSA:3.30.460.10 7 113 1.4E-32 T 16-09-2016 Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 Pfam PF02410 Ribosomal silencing factor during starvation 14 109 7.1E-22 T 16-09-2016 Spa2297_RS10880 20f9e1f1efeed88628e229427617ba3f 148 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.74 T 16-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 PANTHER PTHR30598:SF1 4 164 5.9E-56 T 16-09-2016 Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 PANTHER PTHR30598 4 164 5.9E-56 T 16-09-2016 Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 Gene3D G3DSA:1.10.3480.10 19 117 1.7E-7 T 16-09-2016 IPR020945 DMSO/Nitrate reductase chaperone Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 Pfam PF02613 Nitrate reductase delta subunit 29 144 9.4E-14 T 16-09-2016 IPR020945 DMSO/Nitrate reductase chaperone Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 150 7.8E-27 T 16-09-2016 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 Spa2297_RS27220 f98997ea562051dce4ede47a1994c0eb 164 SUPERFAMILY SSF89155 6 156 4.32E-31 T 16-09-2016 IPR020945 DMSO/Nitrate reductase chaperone Spa2297_RS10400 fd747b95bc7d1b8a374c46a2bbebb54b 501 PANTHER PTHR11785 23 500 5.9E-29 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS10400 fd747b95bc7d1b8a374c46a2bbebb54b 501 Pfam PF13520 Amino acid permease 26 438 1.2E-24 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS10400 fd747b95bc7d1b8a374c46a2bbebb54b 501 PIRSF PIRSF006060 7 488 4.4E-46 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 SUPERFAMILY SSF53474 348 408 2.96E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 SUPERFAMILY SSF53474 127 245 2.96E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 SUPERFAMILY SSF53474 280 319 2.96E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 Gene3D G3DSA:3.40.50.1820 349 401 1.2E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 Gene3D G3DSA:3.40.50.1820 304 305 1.2E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 Gene3D G3DSA:3.40.50.1820 128 246 1.2E-15 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04185 f84edc1c576a421c1ad1e9f98f5dbfbb 457 Pfam PF07519 Tannase and feruloyl esterase 111 233 2.5E-10 T 16-09-2016 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 Pfam PF07336 Putative stress-induced transcription regulator 10 148 2.0E-17 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 PANTHER PTHR35525 1 199 1.1E-48 T 16-09-2016 Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 Pfam PF11706 CGNR zinc finger 152 192 4.5E-10 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 SUPERFAMILY SSF160904 7 191 1.19E-39 T 16-09-2016 Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 Gene3D G3DSA:1.10.3300.10 9 192 3.6E-39 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS02440 ccc45f852c8e779d1041f1f9ac8bcdd8 200 PANTHER PTHR35525:SF3 1 199 1.1E-48 T 16-09-2016 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 423 528 9.9E-14 T 16-09-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 SUPERFAMILY SSF51905 437 463 1.3E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 SUPERFAMILY SSF51905 37 263 1.3E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 Pfam PF01266 FAD dependent oxidoreductase 38 392 2.6E-45 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PANTHER PTHR11985 14 519 2.2E-172 T 16-09-2016 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 352 358 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 381 393 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 50 60 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 49 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 66 78 1.3E-20 T 16-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 PANTHER PTHR11985:SF1 14 519 2.2E-172 T 16-09-2016 Spa2297_RS06455 11bc122550865bf678751d2f38b234f7 538 Gene3D G3DSA:3.50.50.60 35 279 2.2E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 PIRSF PIRSF006232 22 318 8.2E-94 T 16-09-2016 IPR012093 Pirin Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 Pfam PF02678 Pirin 41 146 2.8E-31 T 16-09-2016 IPR003829 Pirin, N-terminal domain Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 PANTHER PTHR13903 21 325 1.9E-195 T 16-09-2016 IPR012093 Pirin Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 SUPERFAMILY SSF51182 24 319 1.01E-83 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 PANTHER PTHR13903:SF13 21 325 1.9E-195 T 16-09-2016 Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 Gene3D G3DSA:2.60.120.10 24 282 2.7E-78 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS16950 941fc63ebec77e1966a4c3cf0f630b1e 325 Pfam PF05726 Pirin C-terminal cupin domain 201 309 1.3E-33 T 16-09-2016 IPR008778 Pirin, C-terminal domain Spa2297_RS15500 dbb0c4129ce66e74b237e49c25345609 293 SUPERFAMILY SSF89392 77 268 8.24E-8 T 16-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spa2297_RS15370 d212a7a7bc0ff8d353975a332fa27f93 245 Pfam PF11209 Protein of unknown function (DUF2993) 21 236 2.4E-28 T 16-09-2016 IPR021373 Protein of unknown function DUF2993 Spa2297_RS26960 3783454f96789a869876a018032e7367 132 PANTHER PTHR11803:SF21 7 130 1.6E-68 T 16-09-2016 Spa2297_RS26960 3783454f96789a869876a018032e7367 132 PANTHER PTHR11803 7 130 1.6E-68 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS26960 3783454f96789a869876a018032e7367 132 Gene3D G3DSA:3.30.1330.40 3 131 5.9E-44 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS26960 3783454f96789a869876a018032e7367 132 SUPERFAMILY SSF55298 5 130 4.4E-36 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS26960 3783454f96789a869876a018032e7367 132 Pfam PF01042 Endoribonuclease L-PSP 14 130 4.1E-34 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 SMART SM00382 27 211 9.3E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 PANTHER PTHR24220 4 248 1.6E-92 T 16-09-2016 Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 Gene3D G3DSA:3.40.50.300 3 233 1.8E-62 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 SUPERFAMILY SSF52540 3 224 8.91E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 Pfam PF00005 ABC transporter 19 167 7.1E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS31670 de4c9dfd6a06f21fdf3b8b75f6906044 257 PANTHER PTHR24220:SF309 4 248 1.6E-92 T 16-09-2016 Spa2297_RS01645 b7b648c53b248131ebe1ba0f0fcd1ed0 194 SUPERFAMILY SSF52540 6 184 7.93E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01645 b7b648c53b248131ebe1ba0f0fcd1ed0 194 PANTHER PTHR11711 9 194 4.4E-70 T 16-09-2016 Spa2297_RS01645 b7b648c53b248131ebe1ba0f0fcd1ed0 194 Gene3D G3DSA:3.40.50.300 5 182 8.8E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01645 b7b648c53b248131ebe1ba0f0fcd1ed0 194 Pfam PF03029 Conserved hypothetical ATP binding protein 13 178 2.0E-26 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS01645 b7b648c53b248131ebe1ba0f0fcd1ed0 194 PANTHER PTHR11711:SF117 9 194 4.4E-70 T 16-09-2016 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 289 3.4E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 Gene3D G3DSA:3.50.50.60 104 233 4.1E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PANTHER PTHR22912 1 281 1.9E-27 T 16-09-2016 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.6E-11 T 16-09-2016 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 5.6E-11 T 16-09-2016 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 5.6E-11 T 16-09-2016 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 Gene3D G3DSA:3.50.50.60 7 103 2.2E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 Gene3D G3DSA:3.50.50.60 234 305 2.2E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 7.4E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 97 105 7.4E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 7.4E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS32180 5f037f5a6269a300ba986c658fd6cde0 385 SUPERFAMILY SSF51905 6 309 3.38E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS05790 49b60bd06888c1d3a0f2b4dab6b1c0c6 310 PANTHER PTHR30606:SF2 7 309 5.6E-99 T 16-09-2016 Spa2297_RS05790 49b60bd06888c1d3a0f2b4dab6b1c0c6 310 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 292 4.2E-62 T 16-09-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Spa2297_RS05790 49b60bd06888c1d3a0f2b4dab6b1c0c6 310 PANTHER PTHR30606 7 309 5.6E-99 T 16-09-2016 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 Gene3D G3DSA:3.30.70.1350 252 333 3.8E-19 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 PANTHER PTHR11562:SF55 3 341 4.0E-148 T 16-09-2016 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 Gene3D G3DSA:1.20.1510.10 56 251 7.2E-37 T 16-09-2016 IPR027469 Cation efflux protein transmembrane domain Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 PANTHER PTHR11562 3 341 4.0E-148 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 SUPERFAMILY SSF160240 253 333 3.92E-17 T 16-09-2016 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 56 332 1.8E-66 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 SUPERFAMILY SSF161111 54 252 1.83E-44 T 16-09-2016 Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 Pfam PF16916 Dimerisation domain of Zinc Transporter 255 332 7.9E-16 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS04805 4215eefd2d3f48eaabd188e0fb910e9d 350 Pfam PF01545 Cation efflux family 58 251 2.5E-38 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS17105 a85963b23bcfefd2767a3af37baae01f 79 Pfam PF02416 mttA/Hcf106 family 3 51 1.7E-9 T 16-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00412 Epoxide hydrolase signature 118 131 9.3E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00412 Epoxide hydrolase signature 104 117 9.3E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00412 Epoxide hydrolase signature 230 246 9.3E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00412 Epoxide hydrolase signature 263 285 9.3E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00412 Epoxide hydrolase signature 40 58 9.3E-13 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PANTHER PTHR10992:SF877 4 288 2.1E-63 T 16-09-2016 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 SUPERFAMILY SSF53474 10 288 6.73E-65 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PANTHER PTHR10992 4 288 2.1E-63 T 16-09-2016 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 Gene3D G3DSA:3.40.50.1820 6 288 8.7E-69 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 Pfam PF00561 alpha/beta hydrolase fold 35 275 2.9E-28 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 232 246 1.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS12330 f6b525a99ab71759b9fbdcd4d4a12b6a 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Pfam PF12848 ABC transporter 243 276 2.8E-5 T 16-09-2016 IPR032781 ABC-transporter extension domain Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 SMART SM00382 377 537 8.1E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 SMART SM00382 30 237 1.2E-12 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Gene3D G3DSA:3.40.50.300 16 103 1.0E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Gene3D G3DSA:3.40.50.300 141 275 1.0E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Gene3D G3DSA:3.40.50.300 373 525 8.1E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 SUPERFAMILY SSF52540 15 236 2.11E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 PANTHER PTHR19211 300 527 5.9E-113 T 16-09-2016 Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 PANTHER PTHR19211 16 277 5.9E-113 T 16-09-2016 Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 SUPERFAMILY SSF52540 373 527 1.27E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Pfam PF00005 ABC transporter 21 193 2.9E-24 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS00105 c8cbf6c230cb317abb48e2a45f3f0b0d 541 Pfam PF00005 ABC transporter 373 497 2.9E-19 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23800 163027285c97788784555f87360653c3 395 Pfam PF02481 DNA recombination-mediator protein A 88 295 3.3E-66 T 16-09-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 Spa2297_RS23800 163027285c97788784555f87360653c3 395 Gene3D G3DSA:3.40.50.450 131 274 2.0E-14 T 16-09-2016 Spa2297_RS23800 163027285c97788784555f87360653c3 395 Gene3D G3DSA:1.10.10.10 328 384 1.3E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23800 163027285c97788784555f87360653c3 395 PANTHER PTHR32039 81 330 1.3E-70 T 16-09-2016 Spa2297_RS23800 163027285c97788784555f87360653c3 395 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 86 303 1.8E-59 T 16-09-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 Spa2297_RS23800 163027285c97788784555f87360653c3 395 SUPERFAMILY SSF102405 111 305 2.9E-35 T 16-09-2016 Spa2297_RS23800 163027285c97788784555f87360653c3 395 PANTHER PTHR32039:SF8 81 330 1.3E-70 T 16-09-2016 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Gene3D G3DSA:3.40.50.300 77 133 3.2E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Gene3D G3DSA:1.25.40.10 469 708 1.6E-14 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 SUPERFAMILY SSF52540 74 283 2.09E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 PANTHER PTHR19959 475 721 2.2E-31 T 16-09-2016 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 PANTHER PTHR19959:SF128 475 721 2.2E-31 T 16-09-2016 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 SUPERFAMILY SSF48452 474 583 1.43E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Pfam PF00931 NB-ARC domain 89 280 5.3E-9 T 16-09-2016 IPR002182 NB-ARC GO:0043531 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Pfam PF13424 Tetratricopeptide repeat 474 536 1.7E-8 T 16-09-2016 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Pfam PF13424 Tetratricopeptide repeat 644 708 4.2E-8 T 16-09-2016 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 SUPERFAMILY SSF48452 554 588 5.38E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 SUPERFAMILY SSF48452 627 726 5.38E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS11700 1eead0194935fc0067ebb047d2ce9adb 740 Pfam PF13374 Tetratricopeptide repeat 562 592 2.5E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 Pfam PF04545 Sigma-70, region 4 139 188 4.1E-15 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 188 8.4E-24 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 SUPERFAMILY SSF88946 14 115 5.69E-23 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 PANTHER PTHR30173 11 193 1.2E-53 T 16-09-2016 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 SUPERFAMILY SSF88659 131 189 3.18E-15 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 Pfam PF04542 Sigma-70 region 2 39 106 6.0E-18 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 PANTHER PTHR30173:SF31 11 193 1.2E-53 T 16-09-2016 Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 Gene3D G3DSA:1.10.10.10 132 191 1.8E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00800 d1a5af17873af4e879aa8a7138def8c8 214 Gene3D G3DSA:1.10.1740.10 16 119 2.6E-25 T 16-09-2016 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Gene3D G3DSA:1.10.150.300 132 201 2.5E-18 T 16-09-2016 IPR023192 TGS-like domain Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 2.9E-132 T 16-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PANTHER PTHR23305 2 362 1.2E-177 T 16-09-2016 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Gene3D G3DSA:3.10.20.30 261 362 9.3E-45 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Gene3D G3DSA:3.40.50.300 3 131 2.2E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Gene3D G3DSA:3.40.50.300 202 260 2.2E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 SUPERFAMILY SSF81271 278 362 1.68E-34 T 16-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PIRSF PIRSF006641 1 362 5.4E-142 T 16-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 1.4E-38 T 16-09-2016 IPR013029 Domain of unknown function DUF933 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 41.974 T 16-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 Pfam PF01926 50S ribosome-binding GTPase 5 124 9.5E-23 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 SUPERFAMILY SSF52540 3 300 1.29E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21435 4be126e8c5b1bb2a5bf135883a251f05 362 PANTHER PTHR23305:SF12 2 362 1.2E-177 T 16-09-2016 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 PANTHER PTHR18934 10 440 1.0E-115 T 16-09-2016 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Pfam PF00270 DEAD/DEAH box helicase 21 168 2.6E-6 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 10 835 5.5E-225 T 16-09-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Gene3D G3DSA:3.40.50.300 10 169 2.1E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 SMART SM00490 244 342 1.7E-8 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 SMART SM00487 8 194 1.5E-20 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 PANTHER PTHR18934:SF118 10 440 1.0E-115 T 16-09-2016 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Gene3D G3DSA:3.40.50.300 223 355 1.1E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Pfam PF04408 Helicase associated domain (HA2) 403 468 4.4E-7 T 16-09-2016 IPR007502 Helicase-associated domain GO:0004386 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 PIRSF PIRSF005496 5 837 9.2E-260 T 16-09-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Pfam PF00271 Helicase conserved C-terminal domain 230 340 5.4E-7 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 SMART SM00847 402 499 7.4E-9 T 16-09-2016 IPR007502 Helicase-associated domain GO:0004386 Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 SUPERFAMILY SSF52540 197 352 4.65E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 SUPERFAMILY SSF52540 20 170 4.65E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08115 ecfa7d25b0e3f6bfb78634d32f9d667a 838 Pfam PF08482 ATP-dependent helicase C-terminal 691 823 1.9E-49 T 16-09-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal Spa2297_RS07130 c4f4fada81ab7e2f16ef4e38abe1d7e8 143 SUPERFAMILY SSF141322 77 141 1.83E-6 T 16-09-2016 Spa2297_RS07130 c4f4fada81ab7e2f16ef4e38abe1d7e8 143 Gene3D G3DSA:2.40.50.140 84 142 9.6E-23 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS07130 c4f4fada81ab7e2f16ef4e38abe1d7e8 143 PANTHER PTHR33507 1 143 1.1E-28 T 16-09-2016 Spa2297_RS07130 c4f4fada81ab7e2f16ef4e38abe1d7e8 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 10 142 1.6E-18 T 16-09-2016 IPR002810 NfeD-like, C-terminal domain Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 Pfam PF02525 Flavodoxin-like fold 3 163 2.8E-30 T 16-09-2016 IPR003680 Flavodoxin-like fold Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 PANTHER PTHR10204 1 214 8.8E-104 T 16-09-2016 Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 24.264 T 16-09-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 SUPERFAMILY SSF52218 1 175 3.19E-34 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 Gene3D G3DSA:3.40.50.360 1 213 2.3E-53 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS00160 28b2016bc5bd9a574117f53b53a8dbe2 220 PANTHER PTHR10204:SF37 1 214 8.8E-104 T 16-09-2016 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 Pfam PF01678 Diaminopimelate epimerase 7 133 1.6E-34 T 16-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 Pfam PF01678 Diaminopimelate epimerase 153 274 4.4E-29 T 16-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 5 281 30.883 T 16-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 Gene3D G3DSA:3.10.310.10 6 130 4.2E-38 T 16-09-2016 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 Gene3D G3DSA:3.10.310.10 131 269 6.0E-38 T 16-09-2016 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 SUPERFAMILY SSF54506 5 135 1.18E-32 T 16-09-2016 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 279 3.5E-65 T 16-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 76 90 - T 16-09-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 SUPERFAMILY SSF54506 142 279 1.55E-34 T 16-09-2016 Spa2297_RS24520 466c328b04d49a37280da5331206ecd4 294 PANTHER PTHR31689 1 285 3.3E-98 T 16-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 Pfam PF00296 Luciferase-like monooxygenase 5 334 4.0E-90 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 SUPERFAMILY SSF51679 5 365 6.15E-93 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 PANTHER PTHR30011:SF1 3 360 5.0E-134 T 16-09-2016 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 Gene3D G3DSA:3.20.20.30 295 365 4.1E-101 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 Gene3D G3DSA:3.20.20.30 4 261 4.1E-101 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02365 6b1acff350726a5da5cc4b0b3cc44167 382 PANTHER PTHR30011 3 360 5.0E-134 T 16-09-2016 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 PANTHER PTHR30532 1 327 2.9E-84 T 16-09-2016 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 Pfam PF01497 Periplasmic binding protein 58 302 1.0E-20 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 Gene3D G3DSA:3.40.50.1980 158 327 2.9E-42 T 16-09-2016 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 SUPERFAMILY SSF53807 39 321 1.96E-49 T 16-09-2016 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 PANTHER PTHR30532:SF1 1 327 2.9E-84 T 16-09-2016 Spa2297_RS01715 4035d65748c6a83ce51c326a0fd397a3 327 Gene3D G3DSA:3.40.50.1980 37 157 2.1E-27 T 16-09-2016 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 Pfam PF00005 ABC transporter 19 166 4.2E-36 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 Gene3D G3DSA:3.40.50.300 1 219 1.4E-73 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 PANTHER PTHR24220:SF470 3 223 1.2E-122 T 16-09-2016 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 SUPERFAMILY SSF52540 1 220 3.55E-71 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 PANTHER PTHR24220 3 223 1.2E-122 T 16-09-2016 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 1.3E-85 T 16-09-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 Spa2297_RS12835 22f3bb463f7f1974cc0d7c3ccd396986 229 SMART SM00382 28 215 7.9E-17 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS28350 d9ab5a637334c11ea35c307cf7a55173 438 Gene3D G3DSA:1.20.1250.20 22 200 2.3E-10 T 16-09-2016 Spa2297_RS28350 d9ab5a637334c11ea35c307cf7a55173 438 SUPERFAMILY SSF103473 20 408 9.02E-28 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS28350 d9ab5a637334c11ea35c307cf7a55173 438 PANTHER PTHR23513:SF6 4 436 7.5E-119 T 16-09-2016 Spa2297_RS28350 d9ab5a637334c11ea35c307cf7a55173 438 PANTHER PTHR23513 4 436 7.5E-119 T 16-09-2016 Spa2297_RS28350 d9ab5a637334c11ea35c307cf7a55173 438 Pfam PF07690 Major Facilitator Superfamily 28 358 4.5E-20 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 SMART SM01118 5 210 4.4E-13 T 16-09-2016 IPR023577 CYTH domain Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 Pfam PF05235 CHAD domain 233 465 1.9E-50 T 16-09-2016 IPR007899 CHAD domain Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 Pfam PF01928 CYTH domain 6 186 1.5E-17 T 16-09-2016 IPR023577 CYTH domain Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 SMART SM00880 233 497 2.4E-70 T 16-09-2016 IPR007899 CHAD domain Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 Gene3D G3DSA:2.40.320.10 5 213 4.3E-46 T 16-09-2016 IPR023577 CYTH domain Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 PANTHER PTHR39339:SF1 2 517 6.5E-101 T 16-09-2016 Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 PANTHER PTHR39339 2 517 6.5E-101 T 16-09-2016 Spa2297_RS30885 3277c8350c63c7c1056d6c006a039953 517 SUPERFAMILY SSF55154 4 209 5.23E-39 T 16-09-2016 IPR033469 CYTH-like domain Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 205 8.3E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 221 233 8.3E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 221 8.3E-16 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 PANTHER PTHR26402 38 254 5.0E-113 T 16-09-2016 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 Gene3D G3DSA:3.40.50.2300 34 157 3.8E-38 T 16-09-2016 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 Pfam PF00072 Response regulator receiver domain 40 151 1.1E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 Gene3D G3DSA:1.10.10.10 158 252 9.2E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 SUPERFAMILY SSF52172 37 169 3.56E-36 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 PANTHER PTHR26402:SF527 38 254 5.0E-113 T 16-09-2016 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 SMART SM00421 188 245 3.2E-28 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 ProSitePatterns PS00622 LuxR-type HTH domain signature. 205 232 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 Pfam PF00196 Bacterial regulatory proteins, luxR family 190 245 4.7E-23 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 SUPERFAMILY SSF46894 174 251 4.08E-24 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS12990 4f728afdc20fb9c77e32239da0a8add6 254 SMART SM00448 38 151 2.5E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 Gene3D G3DSA:1.20.120.530 76 214 9.6E-20 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 Pfam PF07729 FCD domain 85 199 3.3E-17 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 SUPERFAMILY SSF48008 78 207 4.71E-21 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 PANTHER PTHR11751 7 98 1.3E-27 T 16-09-2016 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 9.0E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 9.0E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 SMART SM00345 14 72 1.4E-15 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 67 3.2E-18 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 SMART SM00895 82 202 4.9E-12 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 SUPERFAMILY SSF46785 8 101 4.28E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01255 8ad4f8542c2e2d3668760a4372b84bd6 224 Gene3D G3DSA:1.10.10.10 9 73 2.5E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423 157 399 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423 5 11 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 394 1.6E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423:SF508 5 11 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423:SF508 506 550 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423:SF508 157 399 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 Gene3D G3DSA:3.30.565.10 287 393 1.7E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 SUPERFAMILY SSF55874 271 396 3.15E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 PANTHER PTHR24423 506 550 1.3E-22 T 16-09-2016 Spa2297_RS01630 1a3ec0eb5691962db68b71ced6890b68 632 SMART SM00387 285 396 1.1E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19295 b52d63bdeb27c6b6f961dcda1ed6029b 75 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS19295 b52d63bdeb27c6b6f961dcda1ed6029b 75 Gene3D G3DSA:3.30.70.20 12 68 3.1E-16 T 16-09-2016 Spa2297_RS19295 b52d63bdeb27c6b6f961dcda1ed6029b 75 Pfam PF12838 4Fe-4S dicluster domain 18 65 7.9E-10 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS19295 b52d63bdeb27c6b6f961dcda1ed6029b 75 SUPERFAMILY SSF54862 6 68 3.06E-16 T 16-09-2016 Spa2297_RS26105 1db3599b19807c62f2e3ae70096ddbb0 281 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 246 266 5.9E-7 T 16-09-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 Spa2297_RS02220 23c3046ba67bfdb021e3091f0836977d 225 PANTHER PTHR38074 1 224 6.9E-84 T 16-09-2016 Spa2297_RS02220 23c3046ba67bfdb021e3091f0836977d 225 Gene3D G3DSA:3.60.160.10 33 219 1.1E-39 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS02220 23c3046ba67bfdb021e3091f0836977d 225 Pfam PF01987 Mitochondrial biogenesis AIM24 33 214 7.4E-32 T 16-09-2016 IPR002838 Mitochondrial biogenesis protein AIM24 Spa2297_RS02220 23c3046ba67bfdb021e3091f0836977d 225 PANTHER PTHR38074:SF1 1 224 6.9E-84 T 16-09-2016 Spa2297_RS02220 23c3046ba67bfdb021e3091f0836977d 225 SUPERFAMILY SSF51219 32 218 7.59E-45 T 16-09-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain Spa2297_RS11865 38bc44675149d75e6277704049b24271 302 PANTHER PTHR32243:SF31 25 302 4.0E-121 T 16-09-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 Spa2297_RS11865 38bc44675149d75e6277704049b24271 302 PANTHER PTHR32243 25 302 4.0E-121 T 16-09-2016 Spa2297_RS11865 38bc44675149d75e6277704049b24271 302 SUPERFAMILY SSF161098 36 302 2.8E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11865 38bc44675149d75e6277704049b24271 302 Gene3D G3DSA:1.10.3720.10 36 287 3.7E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS11865 38bc44675149d75e6277704049b24271 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 290 4.1E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 Gene3D G3DSA:1.20.58.110 2 86 1.8E-28 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.568 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 87 4.0E-18 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 PANTHER PTHR33398 2 87 2.9E-31 T 16-09-2016 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 Pfam PF01649 Ribosomal protein S20 2 83 5.2E-27 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 SUPERFAMILY SSF46992 3 86 4.71E-28 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10795 ce58e6e01734e70865112673876dc3b1 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 84 1.4E-22 T 16-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 43 52 - T 16-09-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 131 144 - T 16-09-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 Pfam PF01081 KDPG and KHG aldolase 14 206 8.8E-71 T 16-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 14 212 2.7E-75 T 16-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 SUPERFAMILY SSF51569 14 212 8.42E-66 T 16-09-2016 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 PANTHER PTHR30246 18 220 2.8E-106 T 16-09-2016 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 Gene3D G3DSA:3.20.20.70 15 214 8.0E-75 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS09610 9dfd4c427dc16fd588f761c79685f831 220 PANTHER PTHR30246:SF0 18 220 2.8E-106 T 16-09-2016 Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 PANTHER PTHR30258 19 375 6.3E-175 T 16-09-2016 Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 PANTHER PTHR30258:SF12 19 375 6.3E-175 T 16-09-2016 Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 Pfam PF00437 Type II/IV secretion system protein 52 327 7.7E-82 T 16-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 Gene3D G3DSA:3.30.450.90 49 144 8.2E-26 T 16-09-2016 Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 2 339 1.1E-158 T 16-09-2016 IPR022399 Helicase/secretion neighbourhood ATPase Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 SUPERFAMILY SSF52540 40 350 1.33E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17935 b1d5bcbfb4e3d81c9064aced5ef57f2f 405 Gene3D G3DSA:3.40.50.300 151 366 9.3E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 Pfam PF00149 Calcineurin-like phosphoesterase 2 217 2.6E-11 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 244 3.9E-54 T 16-09-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 PANTHER PTHR30337:SF0 1 270 1.4E-86 T 16-09-2016 Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 PANTHER PTHR30337 1 270 1.4E-86 T 16-09-2016 Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 Gene3D G3DSA:3.60.21.10 2 265 1.4E-72 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 355 1.1E-10 T 16-09-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain Spa2297_RS04770 dfac20f308feeea06cafe05624203d5f 387 SUPERFAMILY SSF56300 2 309 7.21E-55 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 SUPERFAMILY SSF54675 11 144 5.46E-44 T 16-09-2016 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 PIRSF PIRSF000484 8 441 7.2E-103 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 PANTHER PTHR11098:SF8 5 435 3.4E-277 T 16-09-2016 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 PANTHER PTHR11098 5 435 3.4E-277 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 Gene3D G3DSA:3.20.140.10 13 378 3.4E-90 T 16-09-2016 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 SUPERFAMILY SSF51690 146 436 2.65E-80 T 16-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 382 1.6E-126 T 16-09-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS12480 f86ecf7a3917c0671497a49bd7e63395 446 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 331 7.8E-5 T 16-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 Pfam PF00106 short chain dehydrogenase 48 247 1.7E-30 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 Gene3D G3DSA:3.40.50.720 40 296 4.0E-58 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 SUPERFAMILY SSF51735 43 298 4.09E-56 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 192 220 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 131 1.7E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 242 1.7E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 1.7E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 182 1.7E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 264 284 1.7E-16 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS31935 fab3913aad9609aea18319bcb3aac2fe 338 PANTHER PTHR24320 33 336 1.3E-87 T 16-09-2016 Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 Pfam PF07730 Histidine kinase 274 338 1.2E-18 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 Gene3D G3DSA:3.30.565.10 298 389 7.7E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 Gene3D G3DSA:3.30.565.10 435 480 7.7E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 PANTHER PTHR24421 156 483 1.2E-106 T 16-09-2016 Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 SUPERFAMILY SSF55874 359 474 3.54E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17635 28c5dd2e97a9269cdc6ac5db97a5cfa1 483 PANTHER PTHR24421:SF26 156 483 1.2E-106 T 16-09-2016 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 16-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 16-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 Pfam PF00920 Dehydratase family 35 609 2.7E-212 T 16-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 PANTHER PTHR21000:SF11 412 617 0.0 T 16-09-2016 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 PANTHER PTHR21000:SF11 1 376 0.0 T 16-09-2016 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 SUPERFAMILY SSF143975 4 426 3.27E-127 T 16-09-2016 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 2.2E-231 T 16-09-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 PANTHER PTHR21000 412 617 0.0 T 16-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 PANTHER PTHR21000 1 376 0.0 T 16-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 SUPERFAMILY SSF52016 427 613 1.1E-61 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS18455 90add402bde74eb148b37460409493a6 617 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.221 T 16-09-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Pfam PF00501 AMP-binding enzyme 40 444 2.1E-71 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 525 5.6E-10 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 PANTHER PTHR24096 30 534 5.9E-97 T 16-09-2016 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Gene3D G3DSA:2.30.38.10 357 420 5.0E-20 T 16-09-2016 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Gene3D G3DSA:3.30.300.30 438 534 1.6E-19 T 16-09-2016 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 SUPERFAMILY SSF56801 29 534 4.06E-110 T 16-09-2016 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Gene3D G3DSA:3.40.50.980 194 340 1.3E-30 T 16-09-2016 Spa2297_RS02960 5f6191df87565a7e573b4631ae191977 544 Gene3D G3DSA:3.40.50.980 33 193 3.1E-15 T 16-09-2016 Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 PANTHER PTHR23517:SF2 3 412 2.3E-146 T 16-09-2016 Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 Gene3D G3DSA:1.20.1250.20 10 185 2.4E-24 T 16-09-2016 Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 Gene3D G3DSA:1.20.1250.20 204 382 2.8E-14 T 16-09-2016 Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 Pfam PF07690 Major Facilitator Superfamily 11 359 2.1E-31 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 SUPERFAMILY SSF103473 8 389 3.66E-46 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS15590 db0dafd93f8d19d43ed5e7841f84b4c5 425 PANTHER PTHR23517 3 412 2.3E-146 T 16-09-2016 Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 SUPERFAMILY SSF103473 8 391 5.89E-47 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 Pfam PF05977 Transmembrane secretion effector 2 392 1.2E-52 T 16-09-2016 IPR010290 Transmembrane secretion effector Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 PANTHER PTHR23513 1 419 5.1E-179 T 16-09-2016 Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 Gene3D G3DSA:1.20.1250.20 11 192 3.3E-19 T 16-09-2016 Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 Gene3D G3DSA:1.20.1250.20 216 390 6.1E-14 T 16-09-2016 Spa2297_RS14605 819e79948426268f8db0dcdf60bf413c 424 PANTHER PTHR23513:SF6 1 419 5.1E-179 T 16-09-2016 Spa2297_RS30635 52c6679340db5684ae1b04a28a599ef9 232 PANTHER PTHR11922:SF11 17 189 4.3E-32 T 16-09-2016 Spa2297_RS30635 52c6679340db5684ae1b04a28a599ef9 232 SUPERFAMILY SSF52317 15 225 2.81E-39 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS30635 52c6679340db5684ae1b04a28a599ef9 232 Gene3D G3DSA:3.40.50.880 2 226 6.6E-50 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS30635 52c6679340db5684ae1b04a28a599ef9 232 Pfam PF00117 Glutamine amidotransferase class-I 45 181 5.7E-15 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS30635 52c6679340db5684ae1b04a28a599ef9 232 PANTHER PTHR11922 17 189 4.3E-32 T 16-09-2016 Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 257 1.7E-111 T 16-09-2016 IPR017518 Conserved hypothetical protein CHP03084 Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 6.5E-52 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 SUPERFAMILY SSF109854 3 152 7.94E-38 T 16-09-2016 Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 Pfam PF08608 Wyosine base formation 183 233 1.5E-8 T 16-09-2016 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 6.9E-34 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS14515 4e298cbd04179ab4187211d71069a283 264 Gene3D G3DSA:1.20.120.450 5 142 5.6E-11 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS00195 9d747944bb3291fdbac8296230d26252 1276 Gene3D G3DSA:1.25.40.10 502 647 3.9E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00195 9d747944bb3291fdbac8296230d26252 1276 Gene3D G3DSA:1.25.40.10 698 782 3.9E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00195 9d747944bb3291fdbac8296230d26252 1276 SUPERFAMILY SSF48452 500 630 2.21E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 Gene3D G3DSA:3.20.20.80 4 316 3.3E-95 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 Pfam PF01120 Alpha-L-fucosidase 3 312 2.1E-82 T 16-09-2016 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PANTHER PTHR10030 157 411 1.9E-94 T 16-09-2016 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PANTHER PTHR10030 3 141 1.9E-94 T 16-09-2016 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 116 135 1.8E-16 T 16-09-2016 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 300 322 1.8E-16 T 16-09-2016 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 267 288 1.8E-16 T 16-09-2016 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PRINTS PR00741 Glycosyl hydrolase family 29 signature 70 86 1.8E-16 T 16-09-2016 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 SMART SM00812 2 358 1.5E-145 T 16-09-2016 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 PIRSF PIRSF001092 1 423 1.2E-132 T 16-09-2016 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 Spa2297_RS28260 49e97e6e86eecfed52358a473089952c 423 SUPERFAMILY SSF51445 3 317 8.42E-96 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 SUPERFAMILY SSF51621 4 221 2.41E-56 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 8 211 1.3E-38 T 16-09-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 PANTHER PTHR32308 1 270 2.8E-78 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 Gene3D G3DSA:3.20.20.60 4 223 8.5E-69 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 PANTHER PTHR32308:SF0 1 270 2.8E-78 T 16-09-2016 Spa2297_RS08280 5952c6ac9d34aab3a9903461c1bfdf8f 274 PIRSF PIRSF015582 2 273 1.9E-74 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS17665 6ca6e1092dbf1ed13477d733c0ae6b76 152 SUPERFAMILY SSF46785 6 106 6.74E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17665 6ca6e1092dbf1ed13477d733c0ae6b76 152 Gene3D G3DSA:1.10.10.10 3 78 8.4E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17665 6ca6e1092dbf1ed13477d733c0ae6b76 152 Pfam PF12802 MarR family 16 75 5.6E-9 T 16-09-2016 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 SUPERFAMILY SSF81606 166 345 3.27E-11 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 PANTHER PTHR35801 9 354 4.2E-87 T 16-09-2016 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 SMART SM00331 154 348 3.1E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 SUPERFAMILY SSF55874 40 136 3.9E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 Gene3D G3DSA:3.30.565.10 14 136 8.5E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 182 343 3.7E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 PANTHER PTHR35801:SF1 9 354 4.2E-87 T 16-09-2016 Spa2297_RS02075 e5ae007e2f518528d5877945f700a1da 354 Pfam PF13581 Histidine kinase-like ATPase domain 13 135 1.1E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 SUPERFAMILY SSF52540 4 232 7.46E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 PANTHER PTHR24220 6 241 7.5E-112 T 16-09-2016 Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 Pfam PF00005 ABC transporter 21 173 3.1E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 Gene3D G3DSA:3.40.50.300 2 232 1.0E-49 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 PANTHER PTHR24220:SF383 6 241 7.5E-112 T 16-09-2016 Spa2297_RS07135 707bcedc449e69ed82490b2948c6dc31 265 SMART SM00382 29 224 7.7E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS04905 19dca13396175152edc5fa74a2d30a5a 170 Gene3D G3DSA:1.20.120.450 2 169 9.2E-50 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS04905 19dca13396175152edc5fa74a2d30a5a 170 SUPERFAMILY SSF109854 3 165 7.94E-45 T 16-09-2016 Spa2297_RS04905 19dca13396175152edc5fa74a2d30a5a 170 Pfam PF04978 Protein of unknown function (DUF664) 18 166 1.1E-51 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS00355 80404c32e02dc6b2f80d3c0180562c00 298 PANTHER PTHR18964 4 291 6.3E-18 T 16-09-2016 Spa2297_RS00355 80404c32e02dc6b2f80d3c0180562c00 298 Gene3D G3DSA:3.30.420.40 141 270 1.2E-20 T 16-09-2016 Spa2297_RS00355 80404c32e02dc6b2f80d3c0180562c00 298 Pfam PF00480 ROK family 4 292 2.4E-23 T 16-09-2016 IPR000600 ROK family Spa2297_RS00355 80404c32e02dc6b2f80d3c0180562c00 298 SUPERFAMILY SSF53067 3 292 4.15E-36 T 16-09-2016 Spa2297_RS00355 80404c32e02dc6b2f80d3c0180562c00 298 Gene3D G3DSA:3.30.420.40 4 140 6.3E-21 T 16-09-2016 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 PANTHER PTHR22911 12 308 1.2E-105 T 16-09-2016 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 SUPERFAMILY SSF103481 201 303 1.29E-11 T 16-09-2016 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 Pfam PF00892 EamA-like transporter family 12 152 8.8E-14 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 Pfam PF00892 EamA-like transporter family 163 299 1.3E-15 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 PANTHER PTHR22911:SF46 12 308 1.2E-105 T 16-09-2016 Spa2297_RS04990 5ad706fc71f116eaa9b84de828e481de 314 SUPERFAMILY SSF103481 48 156 6.93E-12 T 16-09-2016 Spa2297_RS25825 988cac78a9295351beaeee1a51d11f46 153 Gene3D G3DSA:3.10.180.10 18 146 5.0E-31 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS25825 988cac78a9295351beaeee1a51d11f46 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 140 3.0E-10 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS25825 988cac78a9295351beaeee1a51d11f46 153 PANTHER PTHR36503:SF3 19 145 3.9E-74 T 16-09-2016 Spa2297_RS25825 988cac78a9295351beaeee1a51d11f46 153 SUPERFAMILY SSF54593 18 148 5.1E-24 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS25825 988cac78a9295351beaeee1a51d11f46 153 PANTHER PTHR36503 19 145 3.9E-74 T 16-09-2016 Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 16-09-2016 IPR030489 Transcription regulator Rrf2-type, conserved site Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 2.5E-34 T 16-09-2016 IPR000944 Transcription regulator Rrf2-type Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 SUPERFAMILY SSF46785 2 133 1.86E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 Gene3D G3DSA:1.10.10.10 1 133 2.4E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 PANTHER PTHR33221 2 153 2.0E-41 T 16-09-2016 Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 PANTHER PTHR33221:SF1 2 153 2.0E-41 T 16-09-2016 Spa2297_RS10250 2feb6e7c5a2c361c846bc083d77376eb 164 Pfam PF02082 Transcriptional regulator 1 83 1.5E-27 T 16-09-2016 IPR000944 Transcription regulator Rrf2-type Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 Pfam PF00171 Aldehyde dehydrogenase family 7 447 1.1E-110 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 PANTHER PTHR11699 11 451 1.7E-131 T 16-09-2016 Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 SUPERFAMILY SSF53720 5 451 1.02E-114 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 Gene3D G3DSA:3.40.309.10 240 423 4.1E-37 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 Gene3D G3DSA:3.40.605.10 6 239 5.0E-70 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS02955 ffc68cb6ba811a5de41528548a31f0b5 456 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 PANTHER PTHR24031 440 478 1.4E-223 T 16-09-2016 Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 Gene3D G3DSA:3.40.50.300 265 422 1.3E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 PANTHER PTHR24031:SF334 46 418 1.4E-223 T 16-09-2016 Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 Gene3D G3DSA:3.40.50.300 54 264 1.6E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 SUPERFAMILY SSF52540 127 408 1.32E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 PANTHER PTHR24031:SF334 440 478 1.4E-223 T 16-09-2016 Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 SMART SM00487 75 275 1.3E-50 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 PANTHER PTHR24031 46 418 1.4E-223 T 16-09-2016 Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 Pfam PF00271 Helicase conserved C-terminal domain 292 390 7.6E-24 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 SMART SM00490 309 390 4.1E-27 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS17190 073e6f8ba2b83933ac000bd2eabbc609 520 Pfam PF00270 DEAD/DEAH box helicase 80 249 1.3E-42 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 SUPERFAMILY SSF52402 17 153 6.28E-24 T 16-09-2016 Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 Pfam PF00582 Universal stress protein family 17 153 2.1E-22 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 Gene3D G3DSA:3.40.50.620 18 153 3.8E-24 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 PRINTS PR01438 Universal stress protein signature 16 34 2.7E-5 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 PRINTS PR01438 Universal stress protein signature 131 153 2.7E-5 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS28960 bd5a17581c4d8d4cd383e652e025f65a 153 PANTHER PTHR31964 1 153 4.3E-20 T 16-09-2016 Spa2297_RS18030 3228decf9d50a93bb47b8a425ba5fc0d 569 PANTHER PTHR30509 308 566 1.0E-14 T 16-09-2016 Spa2297_RS18030 3228decf9d50a93bb47b8a425ba5fc0d 569 Pfam PF13515 Fusaric acid resistance protein-like 352 476 1.1E-23 T 16-09-2016 Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 Gene3D G3DSA:3.40.50.720 10 244 1.2E-65 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 Pfam PF00106 short chain dehydrogenase 13 193 1.1E-50 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.4E-21 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.4E-21 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.4E-21 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.4E-21 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.4E-21 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PANTHER PTHR24319 1 245 1.7E-113 T 16-09-2016 Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 193 1.0E-4 T 16-09-2016 Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 SUPERFAMILY SSF51735 10 247 5.35E-64 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS18670 e504d4a58bcbce9e841cf9efd5e4a408 259 PANTHER PTHR24319:SF32 1 245 1.7E-113 T 16-09-2016 Spa2297_RS05170 bb0dd09b8519b1e65c1607ee181e8a8a 201 Pfam PF03029 Conserved hypothetical ATP binding protein 22 190 1.9E-28 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS05170 bb0dd09b8519b1e65c1607ee181e8a8a 201 Gene3D G3DSA:3.40.50.300 14 193 1.9E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05170 bb0dd09b8519b1e65c1607ee181e8a8a 201 PANTHER PTHR11711:SF117 17 197 1.1E-64 T 16-09-2016 Spa2297_RS05170 bb0dd09b8519b1e65c1607ee181e8a8a 201 SUPERFAMILY SSF52540 16 190 9.22E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05170 bb0dd09b8519b1e65c1607ee181e8a8a 201 PANTHER PTHR11711 17 197 1.1E-64 T 16-09-2016 Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 PIRSF PIRSF029171 1 437 1.0E-63 T 16-09-2016 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 Pfam PF03583 Secretory lipase 150 435 3.2E-88 T 16-09-2016 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 Gene3D G3DSA:3.40.50.1820 99 262 1.5E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 Gene3D G3DSA:3.40.50.1820 327 395 1.5E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 PANTHER PTHR34853 9 441 1.3E-122 T 16-09-2016 Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 SUPERFAMILY SSF53474 102 258 6.26E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01725 4b56ac931d1d96394bbbb9cf22557c38 444 SUPERFAMILY SSF53474 323 403 6.26E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 Gene3D G3DSA:1.10.357.10 70 209 1.0E-27 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 67 2.4E-12 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 PANTHER PTHR30055:SF81 9 210 1.5E-115 T 16-09-2016 Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 SUPERFAMILY SSF46689 15 94 2.36E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 Gene3D G3DSA:1.10.10.60 14 64 6.8E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30575 30c6fc9f9613199356a75b173069e23f 212 PANTHER PTHR30055 9 210 1.5E-115 T 16-09-2016 Spa2297_RS29205 109510590f4594cf688fac61d52fd8f1 125 Gene3D G3DSA:3.30.750.24 6 96 5.5E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29205 109510590f4594cf688fac61d52fd8f1 125 SUPERFAMILY SSF52091 5 114 8.24E-16 T 16-09-2016 IPR002645 STAS domain Spa2297_RS29205 109510590f4594cf688fac61d52fd8f1 125 PANTHER PTHR33745 4 124 1.5E-41 T 16-09-2016 Spa2297_RS29205 109510590f4594cf688fac61d52fd8f1 125 Pfam PF01740 STAS domain 11 97 1.2E-5 T 16-09-2016 IPR002645 STAS domain Spa2297_RS06820 e2bc579f8d6546630047972aeb8cfd0a 152 PANTHER PTHR23091:SF264 6 151 7.0E-34 T 16-09-2016 Spa2297_RS06820 e2bc579f8d6546630047972aeb8cfd0a 152 SUPERFAMILY SSF55729 2 149 1.7E-24 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06820 e2bc579f8d6546630047972aeb8cfd0a 152 Gene3D G3DSA:3.40.630.30 6 151 3.3E-26 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS06820 e2bc579f8d6546630047972aeb8cfd0a 152 Pfam PF13673 Acetyltransferase (GNAT) domain 48 136 3.0E-11 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS06820 e2bc579f8d6546630047972aeb8cfd0a 152 PANTHER PTHR23091 6 151 7.0E-34 T 16-09-2016 Spa2297_RS31450 0b46ebcd1d96dc2802ae3e6e404b0fd3 278 SUPERFAMILY SSF161098 5 278 6.07E-74 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31450 0b46ebcd1d96dc2802ae3e6e404b0fd3 278 Gene3D G3DSA:1.10.3720.10 5 265 1.1E-64 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS31450 0b46ebcd1d96dc2802ae3e6e404b0fd3 278 PANTHER PTHR32243:SF8 1 278 9.4E-118 T 16-09-2016 Spa2297_RS31450 0b46ebcd1d96dc2802ae3e6e404b0fd3 278 PANTHER PTHR32243 1 278 9.4E-118 T 16-09-2016 Spa2297_RS31450 0b46ebcd1d96dc2802ae3e6e404b0fd3 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 271 8.6E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26760 2c11ec36abf39628aa2faccf7947cc37 548 PANTHER PTHR33744:SF5 25 548 7.0E-208 T 16-09-2016 Spa2297_RS26760 2c11ec36abf39628aa2faccf7947cc37 548 Gene3D G3DSA:1.10.10.60 487 519 1.2E-4 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26760 2c11ec36abf39628aa2faccf7947cc37 548 Pfam PF07905 Purine catabolism regulatory protein-like family 31 148 5.0E-31 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS26760 2c11ec36abf39628aa2faccf7947cc37 548 PANTHER PTHR33744 25 548 7.0E-208 T 16-09-2016 Spa2297_RS26760 2c11ec36abf39628aa2faccf7947cc37 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 484 542 8.8E-15 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS11155 018132362f6d4a8853f909da8547e74a 212 Gene3D G3DSA:3.40.30.10 3 168 1.4E-12 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS11155 018132362f6d4a8853f909da8547e74a 212 Pfam PF01323 DSBA-like thioredoxin domain 7 168 1.9E-9 T 16-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Spa2297_RS11155 018132362f6d4a8853f909da8547e74a 212 SUPERFAMILY SSF52833 7 170 3.62E-20 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 Gene3D G3DSA:1.10.10.10 8 74 2.0E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 SUPERFAMILY SSF53067 83 387 1.61E-41 T 16-09-2016 Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 Gene3D G3DSA:3.30.420.40 218 359 1.4E-28 T 16-09-2016 Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 Pfam PF12802 MarR family 13 66 1.5E-8 T 16-09-2016 Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 SUPERFAMILY SSF46785 10 74 7.76E-12 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 PANTHER PTHR18964 58 388 5.7E-87 T 16-09-2016 Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 Gene3D G3DSA:3.30.420.40 78 217 9.4E-34 T 16-09-2016 Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 Pfam PF00480 ROK family 121 383 1.2E-27 T 16-09-2016 IPR000600 ROK family Spa2297_RS05455 33b9518c21fc35945d70d9a1fe8ce056 395 PANTHER PTHR18964:SF108 58 388 5.7E-87 T 16-09-2016 Spa2297_RS21445 b31bcea5b76b6e53bec0793d4c8043a6 192 Gene3D G3DSA:3.40.430.10 5 191 3.8E-22 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS21445 b31bcea5b76b6e53bec0793d4c8043a6 192 Pfam PF01872 RibD C-terminal domain 4 184 2.3E-25 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS21445 b31bcea5b76b6e53bec0793d4c8043a6 192 SUPERFAMILY SSF53597 3 191 2.38E-22 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS21445 b31bcea5b76b6e53bec0793d4c8043a6 192 PANTHER PTHR38011:SF2 2 192 4.2E-53 T 16-09-2016 Spa2297_RS21445 b31bcea5b76b6e53bec0793d4c8043a6 192 PANTHER PTHR38011 2 192 4.2E-53 T 16-09-2016 Spa2297_RS19455 71826ff30bcafda8bdfa83192ebb69c9 468 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 136 4.0E-16 T 16-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Spa2297_RS19455 71826ff30bcafda8bdfa83192ebb69c9 468 PANTHER PTHR10884 22 145 6.0E-41 T 16-09-2016 Spa2297_RS19455 71826ff30bcafda8bdfa83192ebb69c9 468 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 148 3.3E-33 T 16-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Spa2297_RS19455 71826ff30bcafda8bdfa83192ebb69c9 468 SUPERFAMILY SSF143243 22 155 6.15E-38 T 16-09-2016 Spa2297_RS21025 309abd9588aaaa56191b3ee0439d6ea3 187 Gene3D G3DSA:3.90.1140.10 9 151 5.6E-12 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS21025 309abd9588aaaa56191b3ee0439d6ea3 187 SUPERFAMILY SSF55144 8 152 3.14E-14 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 Gene3D G3DSA:1.10.357.10 60 197 3.5E-44 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 Gene3D G3DSA:1.10.10.60 4 59 3.3E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 PANTHER PTHR30328:SF19 6 198 1.5E-37 T 16-09-2016 Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 PANTHER PTHR30328 6 198 1.5E-37 T 16-09-2016 Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.1E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 SUPERFAMILY SSF48498 82 196 3.5E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS26650 ea516f67f697869b05b66206dfeeae09 227 SUPERFAMILY SSF46689 7 75 3.54E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 Gene3D G3DSA:3.50.50.60 5 89 5.3E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 Gene3D G3DSA:3.50.50.60 143 219 5.3E-27 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 PANTHER PTHR13847 8 390 1.9E-119 T 16-09-2016 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 Gene3D G3DSA:3.30.9.10 92 142 1.6E-7 T 16-09-2016 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 SUPERFAMILY SSF51905 6 304 9.5E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 PANTHER PTHR13847:SF191 8 390 1.9E-119 T 16-09-2016 Spa2297_RS15630 94dae7429f4cfce9aa6b7378bf5c33a0 401 Pfam PF01266 FAD dependent oxidoreductase 8 390 2.9E-59 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS14905 d599114848b83d60adda5cac32d8f69b 189 PANTHER PTHR34309:SF1 31 187 1.9E-46 T 16-09-2016 Spa2297_RS14905 d599114848b83d60adda5cac32d8f69b 189 PANTHER PTHR34309 31 187 1.9E-46 T 16-09-2016 Spa2297_RS14905 d599114848b83d60adda5cac32d8f69b 189 SUPERFAMILY SSF143744 54 187 4.05E-32 T 16-09-2016 Spa2297_RS14905 d599114848b83d60adda5cac32d8f69b 189 Pfam PF03928 Haem-degrading 62 184 8.2E-29 T 16-09-2016 IPR005624 Haem-degrading Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 SUPERFAMILY SSF53448 26 253 4.51E-53 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 27 254 1.5E-65 T 16-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 28 253 1.1E-73 T 16-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 126 133 - T 16-09-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 PANTHER PTHR32125 25 260 9.5E-70 T 16-09-2016 Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 Gene3D G3DSA:3.90.550.10 25 257 1.7E-68 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 25 256 29.581 T 16-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15085 1a3009a718b1e9f745cdcafb05fd69a7 262 PANTHER PTHR32125:SF4 25 260 9.5E-70 T 16-09-2016 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 Gene3D G3DSA:3.40.1050.10 11 191 2.4E-57 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 PANTHER PTHR11002:SF13 1 193 1.9E-56 T 16-09-2016 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 Pfam PF00484 Carbonic anhydrase 30 180 1.5E-41 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 34 41 - T 16-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 78 98 - T 16-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 SUPERFAMILY SSF53056 3 192 2.88E-52 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 SMART SM00947 22 184 8.4E-54 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS25475 d3a53d59132b84f122032c6af4b474b8 193 PANTHER PTHR11002 1 193 1.9E-56 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 SMART SM00530 18 73 3.5E-18 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 SUPERFAMILY SSF51182 24 181 9.66E-16 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 Gene3D G3DSA:1.10.260.40 16 82 1.3E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 Gene3D G3DSA:2.60.120.10 92 178 3.2E-14 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 Pfam PF07883 Cupin domain 118 177 2.9E-9 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 PANTHER PTHR10245 15 185 2.9E-30 T 16-09-2016 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 PANTHER PTHR10245:SF20 15 185 2.9E-30 T 16-09-2016 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 SUPERFAMILY SSF47413 15 77 4.5E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31140 e3c6bb5cbf6aa3e85483f2ecd53cdb6d 196 Pfam PF01381 Helix-turn-helix 19 73 1.4E-16 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS26995 292cedad26218b8f1eb699ba7e6e8482 277 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 156 1.1E-27 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS26995 292cedad26218b8f1eb699ba7e6e8482 277 Gene3D G3DSA:3.40.50.10320 6 276 5.0E-79 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS26995 292cedad26218b8f1eb699ba7e6e8482 277 PANTHER PTHR12993:SF13 2 233 3.2E-69 T 16-09-2016 Spa2297_RS26995 292cedad26218b8f1eb699ba7e6e8482 277 SUPERFAMILY SSF102588 5 276 7.46E-64 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS26995 292cedad26218b8f1eb699ba7e6e8482 277 PANTHER PTHR12993 2 233 3.2E-69 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS28225 48479e87dbb66753babc85fcc1ed6d6b 261 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 180 3.4E-26 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS28225 48479e87dbb66753babc85fcc1ed6d6b 261 PANTHER PTHR30383 4 260 1.9E-138 T 16-09-2016 Spa2297_RS28225 48479e87dbb66753babc85fcc1ed6d6b 261 SUPERFAMILY SSF52266 5 190 2.6E-36 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS28225 48479e87dbb66753babc85fcc1ed6d6b 261 Gene3D G3DSA:3.40.50.1110 5 191 2.0E-39 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS28225 48479e87dbb66753babc85fcc1ed6d6b 261 PANTHER PTHR30383:SF8 4 260 1.9E-138 T 16-09-2016 Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 SUPERFAMILY SSF54593 4 141 4.03E-24 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 PANTHER PTHR10374:SF9 6 137 2.0E-12 T 16-09-2016 Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 137 5.7E-9 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 PANTHER PTHR10374 6 137 2.0E-12 T 16-09-2016 Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 Gene3D G3DSA:3.10.180.10 5 138 2.9E-20 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS07960 6047f18e8a6a0c6016924258614eb3ba 142 ProSitePatterns PS00934 Glyoxalase I signature 1. 10 31 - T 16-09-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 PANTHER PTHR11601:SF40 33 441 2.7E-167 T 16-09-2016 Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 Pfam PF00266 Aminotransferase class-V 33 421 5.1E-73 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 Gene3D G3DSA:3.90.1150.10 288 371 1.2E-15 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 Gene3D G3DSA:3.90.1150.10 403 428 1.2E-15 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 Gene3D G3DSA:3.40.640.10 49 287 2.0E-66 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 SUPERFAMILY SSF53383 30 429 1.29E-83 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS08840 4e0239521b52ae10850e92cb71f56eaa 454 PANTHER PTHR11601 33 441 2.7E-167 T 16-09-2016 Spa2297_RS28270 c74f354d9757041d1033c9a9425411c9 439 PANTHER PTHR21021:SF19 216 436 4.2E-29 T 16-09-2016 Spa2297_RS28270 c74f354d9757041d1033c9a9425411c9 439 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 243 437 7.8E-40 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28270 c74f354d9757041d1033c9a9425411c9 439 SUPERFAMILY SSF81606 225 436 8.63E-9 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS28270 c74f354d9757041d1033c9a9425411c9 439 PANTHER PTHR21021 216 436 4.2E-29 T 16-09-2016 Spa2297_RS28270 c74f354d9757041d1033c9a9425411c9 439 SMART SM00331 209 437 4.8E-28 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 176 185 - T 16-09-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 PANTHER PTHR19328 43 186 2.1E-23 T 16-09-2016 Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 SUPERFAMILY SSF51445 53 353 6.34E-75 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 Gene3D G3DSA:3.20.20.80 47 350 3.6E-88 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 PANTHER PTHR19328:SF13 43 186 2.1E-23 T 16-09-2016 Spa2297_RS02775 ab3f23f3a47c9025062cd3810abd61c5 358 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 63 313 3.5E-46 T 16-09-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 Gene3D G3DSA:3.40.50.2300 189 325 2.2E-56 T 16-09-2016 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 Pfam PF13377 Periplasmic binding protein-like domain 184 351 1.8E-39 T 16-09-2016 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 PANTHER PTHR30146:SF48 13 351 3.7E-147 T 16-09-2016 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 SUPERFAMILY SSF47413 13 71 5.38E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 SMART SM00354 13 83 4.0E-29 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 3.8E-18 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 PANTHER PTHR30146 13 351 3.7E-147 T 16-09-2016 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 Gene3D G3DSA:3.40.50.2300 66 188 4.3E-36 T 16-09-2016 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 SUPERFAMILY SSF53822 74 350 4.89E-71 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS11850 8f92c2a397343cf86b57d5cdc186137b 351 Gene3D G3DSA:1.10.260.40 14 65 2.4E-24 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 SUPERFAMILY SSF63380 235 330 5.11E-15 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 Pfam PF01794 Ferric reductase like transmembrane component 65 190 1.1E-16 T 16-09-2016 IPR013130 Ferric reductase transmembrane component-like domain Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 Pfam PF00175 Oxidoreductase NAD-binding domain 343 439 5.0E-9 T 16-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 Gene3D G3DSA:2.40.30.10 237 322 5.3E-11 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 SUPERFAMILY SSF52343 321 456 3.4E-27 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PANTHER PTHR19370 230 458 1.0E-61 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PANTHER PTHR19370 12 33 1.0E-61 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 Gene3D G3DSA:3.40.50.80 323 454 1.1E-26 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 Pfam PF08022 FAD-binding domain 260 330 1.7E-4 T 16-09-2016 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PRINTS PR00410 Phenol hydroxylase reductase family signature 326 335 7.0E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PRINTS PR00410 Phenol hydroxylase reductase family signature 426 434 7.0E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PRINTS PR00410 Phenol hydroxylase reductase family signature 342 361 7.0E-7 T 16-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PANTHER PTHR19370:SF68 12 33 1.0E-61 T 16-09-2016 Spa2297_RS06045 588c561e1da308ca380dcb35839873ad 460 PANTHER PTHR19370:SF68 230 458 1.0E-61 T 16-09-2016 Spa2297_RS02065 a73d7489c65937e713fec8b1cecfc663 143 Gene3D G3DSA:3.30.750.24 19 124 5.1E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02065 a73d7489c65937e713fec8b1cecfc663 143 Pfam PF01740 STAS domain 23 108 1.9E-6 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02065 a73d7489c65937e713fec8b1cecfc663 143 SUPERFAMILY SSF52091 17 126 4.71E-18 T 16-09-2016 IPR002645 STAS domain Spa2297_RS02065 a73d7489c65937e713fec8b1cecfc663 143 PANTHER PTHR33745 16 138 4.7E-46 T 16-09-2016 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 SUPERFAMILY SSF53720 8 485 8.77E-147 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 Gene3D G3DSA:3.40.605.10 9 268 2.7E-76 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 Pfam PF00171 Aldehyde dehydrogenase family 15 481 3.7E-153 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 Gene3D G3DSA:3.40.309.10 269 447 9.4E-63 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS11990 b2747e337d92b776f8c9bcb9972d73bf 495 PANTHER PTHR11699 1 494 2.6E-180 T 16-09-2016 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 67 1.7E-19 T 16-09-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 138 5.4E-17 T 16-09-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 SUPERFAMILY SSF50331 50 135 2.34E-18 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 SUPERFAMILY SSF50331 1 68 1.31E-18 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 Pfam PF03459 TOBE domain 75 135 2.2E-18 T 16-09-2016 IPR005116 Transport-associated OB, type 1 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 Pfam PF03459 TOBE domain 4 66 4.2E-20 T 16-09-2016 IPR005116 Transport-associated OB, type 1 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 Gene3D G3DSA:2.40.50.100 1 67 7.7E-24 T 16-09-2016 Spa2297_RS05040 f38b54dcfe168c612462b70f0bd9023e 139 Gene3D G3DSA:2.40.50.100 74 137 6.5E-22 T 16-09-2016 Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 PANTHER PTHR34220 57 397 8.2E-66 T 16-09-2016 Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 391 8.0E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 Gene3D G3DSA:3.30.565.10 287 393 2.1E-15 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 Pfam PF06580 Histidine kinase 194 272 3.2E-23 T 16-09-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 PANTHER PTHR34220:SF3 57 397 8.2E-66 T 16-09-2016 Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 SUPERFAMILY SSF55874 250 390 9.95E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04400 65deb44905bc2b69f5d9f414adabd8d0 405 SMART SM00387 283 393 2.0E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS12980 f72ec6fe5aa95d758369300ebc3cb841 195 PANTHER PTHR13256:SF21 2 195 5.9E-55 T 16-09-2016 Spa2297_RS12980 f72ec6fe5aa95d758369300ebc3cb841 195 Gene3D G3DSA:3.40.630.30 1 173 4.2E-50 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS12980 f72ec6fe5aa95d758369300ebc3cb841 195 SUPERFAMILY SSF55729 1 172 7.78E-40 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS12980 f72ec6fe5aa95d758369300ebc3cb841 195 PANTHER PTHR13256 2 195 5.9E-55 T 16-09-2016 Spa2297_RS12980 f72ec6fe5aa95d758369300ebc3cb841 195 Pfam PF13302 Acetyltransferase (GNAT) domain 10 148 9.5E-26 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Gene3D G3DSA:1.10.601.10 83 158 6.0E-25 T 16-09-2016 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Gene3D G3DSA:1.10.601.10 23 49 6.0E-25 T 16-09-2016 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Gene3D G3DSA:1.10.10.10 250 309 1.1E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PRINTS PR00046 Major sigma-70 factor signature 262 274 3.3E-11 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PRINTS PR00046 Major sigma-70 factor signature 279 294 3.3E-11 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PRINTS PR00046 Major sigma-70 factor signature 294 305 3.3E-11 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PRINTS PR00046 Major sigma-70 factor signature 115 128 3.3E-11 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Pfam PF04545 Sigma-70, region 4 258 307 5.9E-18 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Pfam PF04539 Sigma-70 region 3 172 230 5.5E-11 T 16-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 115 128 - T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Gene3D G3DSA:1.10.10.10 159 214 4.9E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 SUPERFAMILY SSF88946 65 160 7.33E-31 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 SUPERFAMILY SSF88659 164 239 1.44E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 88 308 2.4E-35 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 86 308 3.4E-95 T 16-09-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 SUPERFAMILY SSF88659 226 309 3.55E-17 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PANTHER PTHR30385:SF4 21 312 1.6E-143 T 16-09-2016 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 Pfam PF04542 Sigma-70 region 2 91 160 1.5E-17 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15985 304561b0e28547ddacf54c9b99474668 312 PANTHER PTHR30385 21 312 1.6E-143 T 16-09-2016 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PANTHER PTHR24286:SF32 22 406 3.0E-176 T 16-09-2016 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 SUPERFAMILY SSF48264 12 406 4.45E-93 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 Pfam PF00067 Cytochrome P450 181 372 2.3E-28 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 Pfam PF00067 Cytochrome P450 33 143 1.6E-6 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 127 143 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 286 313 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 269 280 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 144 159 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 188 210 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 314 329 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 345 354 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PRINTS PR00359 B-class P450 signature 354 365 1.2E-40 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 Gene3D G3DSA:1.10.630.10 8 406 1.1E-111 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS30725 3ace1aac982c9d536fea891bd7ffa0fa 408 PANTHER PTHR24286 22 406 3.0E-176 T 16-09-2016 Spa2297_RS17010 7e625323106145179b88826656d79446 335 SUPERFAMILY SSF56219 115 329 3.93E-28 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS17010 7e625323106145179b88826656d79446 335 Gene3D G3DSA:3.60.10.10 115 329 4.3E-12 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS17010 7e625323106145179b88826656d79446 335 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 119 322 2.2E-17 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 15 423 1.0E-167 T 16-09-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 Pfam PF04261 Dyp-type peroxidase family 71 412 2.7E-110 T 16-09-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 71 412 1.9E-98 T 16-09-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 PANTHER PTHR30521:SF4 54 424 1.9E-164 T 16-09-2016 Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 PANTHER PTHR30521 54 424 1.9E-164 T 16-09-2016 Spa2297_RS16205 54e88c28a51cdae559d4f9c8f64f6631 424 SUPERFAMILY SSF54909 66 417 1.97E-83 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 PANTHER PTHR11236 57 334 5.2E-108 T 16-09-2016 Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 Pfam PF00425 chorismate binding enzyme 79 327 1.3E-72 T 16-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 PRINTS PR00095 Anthranilate synthase component I signature 186 199 2.2E-10 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 PRINTS PR00095 Anthranilate synthase component I signature 282 296 2.2E-10 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 PRINTS PR00095 Anthranilate synthase component I signature 266 280 2.2E-10 T 16-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 SUPERFAMILY SSF56322 46 334 1.83E-91 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS05890 cc725f08aa776c16f44ebcbcc1a6080c 350 Gene3D G3DSA:3.60.120.10 53 335 4.3E-100 T 16-09-2016 IPR005801 ADC synthase GO:0009058 Spa2297_RS16925 40a2e61ece9db919bdcf26139624096d 168 SUPERFAMILY SSF54518 2 152 8.63E-32 T 16-09-2016 IPR025659 Tubby C-terminal-like domain Spa2297_RS16925 40a2e61ece9db919bdcf26139624096d 168 Pfam PF04525 LURP-one-related 13 152 8.2E-31 T 16-09-2016 IPR007612 LURP1-related protein domain Spa2297_RS16925 40a2e61ece9db919bdcf26139624096d 168 PANTHER PTHR31087:SF11 9 164 1.6E-34 T 16-09-2016 Spa2297_RS16925 40a2e61ece9db919bdcf26139624096d 168 PANTHER PTHR31087 9 164 1.6E-34 T 16-09-2016 Spa2297_RS28125 8cd39f860a2ba96b586004da58fba3ea 250 Gene3D G3DSA:3.90.550.10 2 245 2.7E-34 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS28125 8cd39f860a2ba96b586004da58fba3ea 250 Pfam PF00483 Nucleotidyl transferase 3 166 1.3E-10 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS28125 8cd39f860a2ba96b586004da58fba3ea 250 PANTHER PTHR22572:SF9 2 242 5.7E-68 T 16-09-2016 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 Spa2297_RS28125 8cd39f860a2ba96b586004da58fba3ea 250 PANTHER PTHR22572 2 242 5.7E-68 T 16-09-2016 Spa2297_RS28125 8cd39f860a2ba96b586004da58fba3ea 250 SUPERFAMILY SSF53448 1 242 1.06E-33 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 SMART SM00347 35 135 4.9E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 PANTHER PTHR33164 18 159 2.3E-23 T 16-09-2016 Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 Gene3D G3DSA:1.10.10.10 13 149 2.8E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 SUPERFAMILY SSF46785 16 146 4.32E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 Pfam PF12802 MarR family 42 99 3.5E-14 T 16-09-2016 Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 1.6E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 1.6E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS29340 7f199b1a5047ac9438bf3bdf7e64ea8d 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 1.6E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 Pfam PF04030 D-arabinono-1,4-lactone oxidase 390 450 1.3E-8 T 16-09-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 PANTHER PTHR13878:SF52 4 451 9.1E-143 T 16-09-2016 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 PANTHER PTHR13878 4 451 9.1E-143 T 16-09-2016 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 SUPERFAMILY SSF56176 12 184 1.39E-36 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 Gene3D G3DSA:3.30.465.10 71 183 3.0E-24 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS20440 ca7b57339d14bffcbad748c958608c76 453 Pfam PF01565 FAD binding domain 21 154 2.7E-23 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 16-09-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 SUPERFAMILY SSF54211 3 130 4.17E-41 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 Gene3D G3DSA:3.30.70.240 139 205 4.1E-13 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 PANTHER PTHR16301 1 208 7.0E-61 T 16-09-2016 IPR023582 Impact family Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 Gene3D G3DSA:3.30.230.30 5 131 1.1E-45 T 16-09-2016 IPR001498 Impact, N-terminal Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 1.9E-15 T 16-09-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 SUPERFAMILY SSF54980 138 199 6.33E-16 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 6.0E-29 T 16-09-2016 IPR001498 Impact, N-terminal Spa2297_RS04775 35d03f2dc557224cdfd3a1ceda069022 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 2.3E-56 T 16-09-2016 IPR015796 Impact family, bacterial/archaeal Spa2297_RS08680 2be94cacc9fe2823fc181846e4472c7c 81 PANTHER PTHR37424:SF1 5 76 2.2E-19 T 16-09-2016 Spa2297_RS08680 2be94cacc9fe2823fc181846e4472c7c 81 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 53 5.4E-11 T 16-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain Spa2297_RS08680 2be94cacc9fe2823fc181846e4472c7c 81 PANTHER PTHR37424 5 76 2.2E-19 T 16-09-2016 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 Gene3D G3DSA:4.10.520.10 1 91 3.1E-29 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 16-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.2E-8 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.2E-8 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.2E-8 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.1E-28 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 SMART SM00411 1 91 4.1E-39 T 16-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 PANTHER PTHR33175 1 92 9.9E-36 T 16-09-2016 Spa2297_RS12745 5d7f776c44fbd51dc6591fb1a5cc51da 93 SUPERFAMILY SSF47729 1 91 4.86E-27 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 PANTHER PTHR23514 1 407 1.1E-129 T 16-09-2016 Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 Pfam PF07690 Major Facilitator Superfamily 21 286 1.6E-15 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 Gene3D G3DSA:1.20.1250.20 233 406 1.1E-13 T 16-09-2016 Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 SUPERFAMILY SSF103473 12 407 1.24E-39 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 Gene3D G3DSA:1.20.1250.20 17 193 2.8E-13 T 16-09-2016 Spa2297_RS01155 3cbc45aad41990a7463d16cdb3637488 407 PANTHER PTHR23514:SF13 1 407 1.1E-129 T 16-09-2016 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 PANTHER PTHR30614:SF9 1 215 4.2E-130 T 16-09-2016 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 PANTHER PTHR30614 1 215 4.2E-130 T 16-09-2016 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 5 213 1.0E-68 T 16-09-2016 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 210 1.8E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 104 4.0E-23 T 16-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 Gene3D G3DSA:1.10.3720.10 8 210 1.4E-44 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12080 37df4511a5f44f87dce0f2a971e061ec 233 SUPERFAMILY SSF161098 6 198 3.79E-38 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 Pfam PF00994 Probable molybdopterin binding domain 19 159 2.9E-28 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 SMART SM00852 18 160 2.2E-21 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 SUPERFAMILY SSF53218 15 165 2.09E-40 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 16 152 7.3E-29 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 76 89 - T 16-09-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 Gene3D G3DSA:3.40.980.10 14 166 3.2E-50 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13840 e513e0565fc977641ea665275857ff96 179 PANTHER PTHR10192 8 168 2.0E-61 T 16-09-2016 Spa2297_RS27035 56b09be6df9c288354c00bd95bbebcb6 115 SUPERFAMILY SSF54593 8 108 4.95E-13 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS27035 56b09be6df9c288354c00bd95bbebcb6 115 Gene3D G3DSA:3.10.180.10 4 109 1.8E-14 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS21000 229ce7ad2e230b7068ccb7338aeafb51 132 Pfam PF14155 Domain of unknown function (DUF4307) 22 129 1.4E-31 T 16-09-2016 IPR025443 Protein of unknown function DUF4307 Spa2297_RS15185 60383b2a96fcf98a745c03ce32e2177e 361 Gene3D G3DSA:3.90.1720.10 239 343 1.3E-35 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS15185 60383b2a96fcf98a745c03ce32e2177e 361 PANTHER PTHR21666 21 43 4.6E-28 T 16-09-2016 Spa2297_RS15185 60383b2a96fcf98a745c03ce32e2177e 361 PANTHER PTHR21666 246 340 4.6E-28 T 16-09-2016 Spa2297_RS15185 60383b2a96fcf98a745c03ce32e2177e 361 SUPERFAMILY SSF54001 241 352 2.4E-32 T 16-09-2016 Spa2297_RS15185 60383b2a96fcf98a745c03ce32e2177e 361 Pfam PF00877 NlpC/P60 family 255 333 3.3E-18 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 PANTHER PTHR23026 89 218 3.0E-41 T 16-09-2016 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 PANTHER PTHR23026 1 52 3.0E-41 T 16-09-2016 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 SUPERFAMILY SSF55469 1 218 3.66E-43 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 PANTHER PTHR23026:SF90 1 52 3.0E-41 T 16-09-2016 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 Gene3D G3DSA:3.40.109.10 1 91 3.8E-46 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 Gene3D G3DSA:3.40.109.10 123 220 3.8E-46 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 PANTHER PTHR23026:SF90 89 218 3.0E-41 T 16-09-2016 Spa2297_RS00155 ebfb113190424cf4c0c2732459e385e0 221 Pfam PF00881 Nitroreductase family 8 197 2.8E-29 T 16-09-2016 IPR029479 Nitroreductase Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 SMART SM00220 23 644 9.7E-8 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 PANTHER PTHR22983 569 921 5.5E-196 T 16-09-2016 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 Gene3D G3DSA:1.10.510.10 534 645 1.9E-17 T 16-09-2016 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 Gene3D G3DSA:1.10.510.10 158 194 1.9E-17 T 16-09-2016 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 Pfam PF07714 Protein tyrosine kinase 98 190 7.9E-7 T 16-09-2016 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain GO:0004672|GO:0006468 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 PANTHER PTHR22983:SF13 569 921 5.5E-196 T 16-09-2016 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 Gene3D G3DSA:3.30.200.20 107 157 1.9E-6 T 16-09-2016 Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 SUPERFAMILY SSF56112 541 662 4.43E-25 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS20145 7bf9aaa1153cad75fa31bcc970f974d3 945 SUPERFAMILY SSF56112 102 193 4.43E-25 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS01845 80e289529ef80e6f76f586333dab8985 254 SUPERFAMILY SSF109854 4 132 1.03E-8 T 16-09-2016 Spa2297_RS01845 80e289529ef80e6f76f586333dab8985 254 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 6.7E-18 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS01845 80e289529ef80e6f76f586333dab8985 254 Pfam PF07398 MDMPI C-terminal domain 140 243 1.7E-12 T 16-09-2016 IPR010872 MDMPI C-terminal Spa2297_RS01845 80e289529ef80e6f76f586333dab8985 254 PANTHER PTHR40758 1 254 8.7E-85 T 16-09-2016 Spa2297_RS01845 80e289529ef80e6f76f586333dab8985 254 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 126 9.6E-17 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 Pfam PF13229 Right handed beta helix region 95 239 4.5E-11 T 16-09-2016 Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 Gene3D G3DSA:2.160.20.10 22 297 2.3E-29 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 184 207 8100.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 124 146 600.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 102 123 74.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 148 176 11.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 298 321 8000.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 238 260 690.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SMART SM00710 209 231 190.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS02780 5e4e6646bc44ed9cf8607249dddb4467 321 SUPERFAMILY SSF51126 36 315 1.11E-35 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS09525 e5202a6c0205de33faa089e3376a026f 349 PANTHER PTHR22935 8 326 4.7E-62 T 16-09-2016 Spa2297_RS09525 e5202a6c0205de33faa089e3376a026f 349 Pfam PF00144 Beta-lactamase 11 335 1.9E-62 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS09525 e5202a6c0205de33faa089e3376a026f 349 Gene3D G3DSA:3.40.710.10 11 327 1.3E-67 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS09525 e5202a6c0205de33faa089e3376a026f 349 SUPERFAMILY SSF56601 12 328 1.63E-72 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS07985 73bd5055fa88d510d1a3f6fe53f8bdb0 210 SUPERFAMILY SSF52540 31 163 7.42E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07985 73bd5055fa88d510d1a3f6fe53f8bdb0 210 Gene3D G3DSA:3.40.50.300 25 199 1.3E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 Gene3D G3DSA:2.40.50.140 1 67 2.4E-18 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-8 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 PRINTS PR00050 Cold shock protein signature 39 57 1.6E-8 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-8 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 SUPERFAMILY SSF50249 1 65 1.47E-15 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 SMART SM00357 3 66 1.3E-13 T 16-09-2016 IPR011129 Cold shock protein GO:0003676 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 PANTHER PTHR11544 1 143 1.6E-20 T 16-09-2016 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 Pfam PF00313 'Cold-shock' DNA-binding domain 4 64 4.8E-13 T 16-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Spa2297_RS28700 997c14d5f8a9f01a7bdb6c5ce2080ebb 144 PANTHER PTHR11544:SF43 1 143 1.6E-20 T 16-09-2016 Spa2297_RS17415 ef2aefaddf4795f7b9651d070a32e08e 63 Pfam PF05122 Mobile element transfer protein 12 60 7.6E-31 T 16-09-2016 IPR007806 Mobile element transfer Spa2297_RS28020 f209e192d24af7cd0c4ad255265021a0 392 SUPERFAMILY SSF51735 11 161 9.4E-18 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28020 f209e192d24af7cd0c4ad255265021a0 392 Gene3D G3DSA:3.40.50.720 13 167 6.7E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS28020 f209e192d24af7cd0c4ad255265021a0 392 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 13 135 4.7E-13 T 16-09-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 Spa2297_RS28020 f209e192d24af7cd0c4ad255265021a0 392 PANTHER PTHR12286 4 388 9.6E-131 T 16-09-2016 Spa2297_RS28020 f209e192d24af7cd0c4ad255265021a0 392 PANTHER PTHR12286:SF4 4 388 9.6E-131 T 16-09-2016 Spa2297_RS16690 10f7f406cb39710d1e09cbd37c4cdd47 295 PANTHER PTHR22936 83 284 9.3E-50 T 16-09-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 Spa2297_RS16690 10f7f406cb39710d1e09cbd37c4cdd47 295 Gene3D G3DSA:1.20.1540.10 84 261 3.3E-41 T 16-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spa2297_RS16690 10f7f406cb39710d1e09cbd37c4cdd47 295 Pfam PF01694 Rhomboid family 128 263 1.7E-37 T 16-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spa2297_RS16690 10f7f406cb39710d1e09cbd37c4cdd47 295 SUPERFAMILY SSF144091 81 268 1.44E-44 T 16-09-2016 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 Gene3D G3DSA:1.10.510.10 106 279 4.0E-41 T 16-09-2016 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 SUPERFAMILY SSF56112 11 271 3.99E-62 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 Gene3D G3DSA:3.30.200.20 15 97 9.0E-15 T 16-09-2016 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 PANTHER PTHR24362 1 307 8.8E-97 T 16-09-2016 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 SMART SM00220 22 270 4.1E-36 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 PANTHER PTHR24362:SF282 1 307 8.8E-97 T 16-09-2016 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 Pfam PF00069 Protein kinase domain 23 267 1.4E-35 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS14520 d2a51de2ee4a462a1c4ccd9c426b9614 627 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 50 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS21215 9406cd2aea5459f80a217ab85855db42 129 Pfam PF02643 Uncharacterized ACR, COG1430 31 124 6.0E-17 T 16-09-2016 IPR003795 Protein of unknown function DUF192 Spa2297_RS31135 2a4b1b0ce12d949f1ea77511545b85ac 172 SUPERFAMILY SSF81296 31 171 5.18E-36 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS31135 2a4b1b0ce12d949f1ea77511545b85ac 172 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 2.3E-17 T 16-09-2016 IPR004302 Chitin-binding protein, N-terminal Spa2297_RS31135 2a4b1b0ce12d949f1ea77511545b85ac 172 PANTHER PTHR34823 1 172 1.3E-72 T 16-09-2016 Spa2297_RS31135 2a4b1b0ce12d949f1ea77511545b85ac 172 Gene3D G3DSA:2.70.50.50 31 171 2.3E-31 T 16-09-2016 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 50 274 4.8E-42 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 PANTHER PTHR11410 17 279 1.1E-83 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 ProSitePatterns PS00449 ATP synthase a subunit signature. 203 212 - T 16-09-2016 IPR023011 ATPase, F0 complex, subunit A, active site Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 PANTHER PTHR11410:SF7 17 279 1.1E-83 T 16-09-2016 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 PRINTS PR00123 ATP synthase A subunit signature 258 273 1.2E-16 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 PRINTS PR00123 ATP synthase A subunit signature 115 131 1.2E-16 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 PRINTS PR00123 ATP synthase A subunit signature 200 222 1.2E-16 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 Pfam PF00119 ATP synthase A chain 58 271 5.1E-50 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 Hamap MF_01393 ATP synthase subunit a [atpB]. 56 278 13.33 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 SUPERFAMILY SSF81336 107 272 1.44E-34 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS22670 e660e817ba1a348adf8e7e9a0c9a8570 279 Gene3D G3DSA:1.20.120.220 107 278 1.9E-38 T 16-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 SUPERFAMILY SSF55821 1 205 4.58E-59 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 PANTHER PTHR17490 1 205 4.1E-88 T 16-09-2016 Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 Gene3D G3DSA:3.90.870.10 2 205 1.3E-60 T 16-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 Pfam PF01300 Telomere recombination 24 198 5.2E-41 T 16-09-2016 IPR006070 YrdC-like domain GO:0003725 Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 PANTHER PTHR17490:SF7 1 205 4.1E-88 T 16-09-2016 Spa2297_RS01900 4e75f0de98a15f773414c2a3355282e9 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 1.2E-53 T 16-09-2016 IPR006070 YrdC-like domain GO:0003725 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 Gene3D G3DSA:1.25.40.10 466 789 7.0E-20 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 SUPERFAMILY SSF46894 791 864 4.42E-18 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 Gene3D G3DSA:1.10.10.10 796 864 4.6E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 SUPERFAMILY SSF52540 50 108 4.55E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 SUPERFAMILY SSF52540 137 252 4.55E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 SMART SM00421 802 859 8.2E-20 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 819 835 4.4E-5 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 805 819 4.4E-5 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 835 847 4.4E-5 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 Pfam PF00196 Bacterial regulatory proteins, luxR family 805 859 1.2E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS25855 5d223a68bbb297997616a63d34717639 865 Gene3D G3DSA:3.40.50.300 54 181 5.9E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22360 cef1d8e383aa0a42c170764598972fa3 146 PANTHER PTHR36221 1 146 1.8E-38 T 16-09-2016 Spa2297_RS22360 cef1d8e383aa0a42c170764598972fa3 146 Pfam PF05331 Protein of unknown function (DUF742) 18 146 2.3E-43 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 PANTHER PTHR11019 5 115 5.1E-31 T 16-09-2016 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 Gene3D G3DSA:1.10.10.60 8 62 1.2E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 SMART SM00342 24 107 2.1E-30 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 SUPERFAMILY SSF46689 60 110 1.03E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 Pfam PF12833 Helix-turn-helix domain 30 109 2.2E-22 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 SUPERFAMILY SSF46689 8 58 3.18E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS27155 894d72b4cf85b30cb8ec0a412d8a8bd8 142 Gene3D G3DSA:1.10.10.60 63 114 7.3E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 2.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PRINTS PR00412 Epoxide hydrolase signature 47 62 2.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PRINTS PR00412 Epoxide hydrolase signature 27 45 2.3E-8 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 Gene3D G3DSA:3.40.50.1820 3 272 1.5E-51 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PANTHER PTHR10992:SF884 164 273 2.4E-97 T 16-09-2016 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PANTHER PTHR10992:SF884 5 145 2.4E-97 T 16-09-2016 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PANTHER PTHR10992 164 273 2.4E-97 T 16-09-2016 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 PANTHER PTHR10992 5 145 2.4E-97 T 16-09-2016 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 Pfam PF12697 Alpha/beta hydrolase family 23 265 2.7E-22 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31390 846f4845122eafd0c69244fbbcf4f930 278 SUPERFAMILY SSF53474 3 272 7.65E-49 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 Gene3D G3DSA:3.40.50.720 196 297 2.9E-25 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 SMART SM00829 9 360 0.0015 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 155 2.5E-21 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 Gene3D G3DSA:3.90.180.10 3 195 2.0E-51 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 SUPERFAMILY SSF51735 160 327 1.55E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 Pfam PF00107 Zinc-binding dehydrogenase 198 287 4.6E-16 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 SUPERFAMILY SSF50129 2 194 4.87E-55 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 PANTHER PTHR11695 138 363 5.0E-135 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 PANTHER PTHR11695 15 107 5.0E-135 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 16-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 PANTHER PTHR11695:SF571 138 363 5.0E-135 T 16-09-2016 Spa2297_RS31890 6fdf2f791b4d5cce81c3f4caa468092e 370 PANTHER PTHR11695:SF571 15 107 5.0E-135 T 16-09-2016 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 SUPERFAMILY SSF46689 29 92 8.48E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 PANTHER PTHR30055:SF93 23 256 1.7E-76 T 16-09-2016 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 Gene3D G3DSA:1.10.357.10 25 250 9.2E-61 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 SUPERFAMILY SSF48498 103 246 5.89E-24 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 PANTHER PTHR30055 23 256 1.7E-76 T 16-09-2016 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 84 2.5E-9 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14575 cbe4c4e12c26ba829a09bad710439c57 268 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 99 244 1.9E-35 T 16-09-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 24 414 6.9E-153 T 16-09-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA01014 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 37 341 2.2E-89 T 16-09-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 SUPERFAMILY SSF55931 290 417 2.65E-37 T 16-09-2016 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 SUPERFAMILY SSF55931 29 254 2.65E-37 T 16-09-2016 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 PANTHER PTHR34378:SF2 1 433 2.8E-177 T 16-09-2016 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 PANTHER PTHR34378 1 433 2.8E-177 T 16-09-2016 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 PIRSF PIRSF017901 2 431 1.6E-119 T 16-09-2016 Spa2297_RS29085 841a79a7262353bf441c1e18a4b5fd13 433 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 12 412 32.534 T 16-09-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA01014 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 SMART SM00947 35 173 1.9E-26 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 Pfam PF00484 Carbonic anhydrase 43 109 2.1E-10 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 PANTHER PTHR11002 16 172 1.9E-50 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 Gene3D G3DSA:3.40.1050.10 15 172 2.6E-33 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 SUPERFAMILY SSF53056 16 172 7.85E-35 T 16-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spa2297_RS08570 59804130a47fb37b3e6ca3df1f2a626b 175 PANTHER PTHR11002:SF9 16 172 1.9E-50 T 16-09-2016 Spa2297_RS04045 032a1a8eaa1d3e108e552dfce20d2cf3 369 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 13 342 4.2E-133 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS04045 032a1a8eaa1d3e108e552dfce20d2cf3 369 PANTHER PTHR10361:SF31 3 349 1.4E-163 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS04045 032a1a8eaa1d3e108e552dfce20d2cf3 369 PANTHER PTHR10361 3 349 1.4E-163 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS04045 032a1a8eaa1d3e108e552dfce20d2cf3 369 Pfam PF01758 Sodium Bile acid symporter family 58 254 1.2E-64 T 16-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spa2297_RS04045 032a1a8eaa1d3e108e552dfce20d2cf3 369 PIRSF PIRSF005508 3 353 2.6E-138 T 16-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 PANTHER PTHR33991 2 247 2.9E-56 T 16-09-2016 Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 Pfam PF11967 Recombination protein O N terminal 1 85 1.3E-28 T 16-09-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 SUPERFAMILY SSF57863 88 238 8.63E-39 T 16-09-2016 Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 244 1.7E-35 T 16-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 SUPERFAMILY SSF50249 1 85 7.37E-19 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 Hamap MF_00201 DNA repair protein RecO [recO]. 2 249 26.786 T 16-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 Gene3D G3DSA:2.40.50.140 1 86 3.5E-35 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS10590 218d686960cf51c47fa76696ceda19b2 249 Pfam PF02565 Recombination protein O C terminal 91 244 7.3E-33 T 16-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 Pfam PF00005 ABC transporter 30 169 9.6E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 Pfam PF08402 TOBE domain 288 368 6.2E-14 T 16-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 SUPERFAMILY SSF50331 245 368 1.81E-16 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 SMART SM00382 38 266 1.4E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 Gene3D G3DSA:2.40.50.100 246 294 3.7E-4 T 16-09-2016 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 SUPERFAMILY SSF52540 14 250 3.41E-86 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 Gene3D G3DSA:3.40.50.300 14 242 2.6E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 PANTHER PTHR24220:SF150 15 255 7.6E-139 T 16-09-2016 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 366 1.6E-110 T 16-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 Spa2297_RS24015 8ddce31dcceeeeb1095ac453460442db 386 PANTHER PTHR24220 15 255 7.6E-139 T 16-09-2016 Spa2297_RS05855 49aa31ebe947089278e90ef14adb1529 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS29565 2a484c0d45a6361dbf42d4f4411dbc20 230 PANTHER PTHR35568 1 222 2.2E-98 T 16-09-2016 Spa2297_RS29565 2a484c0d45a6361dbf42d4f4411dbc20 230 Pfam PF13309 HTH domain 152 212 8.4E-16 T 16-09-2016 Spa2297_RS29565 2a484c0d45a6361dbf42d4f4411dbc20 230 Pfam PF08348 YheO-like PAS domain 14 123 7.8E-33 T 16-09-2016 IPR013559 YheO-like Spa2297_RS29565 2a484c0d45a6361dbf42d4f4411dbc20 230 PANTHER PTHR35568:SF1 1 222 2.2E-98 T 16-09-2016 Spa2297_RS29565 2a484c0d45a6361dbf42d4f4411dbc20 230 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 19 121 8.0E-48 T 16-09-2016 IPR013559 YheO-like Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 Gene3D G3DSA:1.10.3720.10 92 298 1.0E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 PANTHER PTHR30465:SF2 13 303 1.7E-123 T 16-09-2016 Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 SUPERFAMILY SSF161098 96 282 2.94E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 PANTHER PTHR30465 13 303 1.7E-123 T 16-09-2016 Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 72 6.9E-12 T 16-09-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spa2297_RS01015 f7e5a1740b9e680002268d163c86968f 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 300 4.8E-27 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 Gene3D G3DSA:2.160.10.10 61 210 1.4E-39 T 16-09-2016 Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 PANTHER PTHR23416:SF50 83 261 8.4E-39 T 16-09-2016 Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 PANTHER PTHR23416 83 261 8.4E-39 T 16-09-2016 Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 SUPERFAMILY SSF51161 53 209 9.43E-38 T 16-09-2016 IPR011004 Trimeric LpxA-like Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 161 189 - T 16-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 130 0.0015 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS04825 d38026da79c62f0367e4c62712b99107 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 153 187 1.1E-10 T 16-09-2016 IPR001451 Hexapeptide repeat Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 Gene3D G3DSA:2.60.40.710 48 197 2.1E-46 T 16-09-2016 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 SUPERFAMILY SSF49384 46 197 2.93E-43 T 16-09-2016 IPR008965 Carbohydrate-binding domain GO:0030246 Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 SUPERFAMILY SSF49899 216 457 6.71E-20 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 Pfam PF00722 Glycosyl hydrolases family 16 261 456 6.1E-6 T 16-09-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 Pfam PF00942 Cellulose binding domain 50 132 1.0E-20 T 16-09-2016 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 SMART SM01067 50 133 1.4E-30 T 16-09-2016 IPR001956 Bacterial type 3a cellulose-binding domain GO:0005975|GO:0030248 Spa2297_RS30935 d7222779b89820e0631f7df94e504d12 491 Gene3D G3DSA:2.60.120.200 228 457 7.1E-19 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 Gene3D G3DSA:3.40.50.2300 171 252 4.3E-6 T 16-09-2016 Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 PANTHER PTHR34296 10 345 2.5E-128 T 16-09-2016 Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 SUPERFAMILY SSF53822 52 299 3.53E-16 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 Gene3D G3DSA:3.40.50.2300 40 170 9.0E-45 T 16-09-2016 Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 PANTHER PTHR34296:SF2 10 345 2.5E-128 T 16-09-2016 Spa2297_RS20675 972a12e202331542cba3957079a58a68 348 Pfam PF02608 Basic membrane protein 45 347 2.7E-55 T 16-09-2016 IPR003760 Basic membrane lipoprotein GO:0005886 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 Gene3D G3DSA:3.40.30.10 2 99 5.1E-29 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 Pfam PF00085 Thioredoxin 3 100 7.4E-26 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 PRINTS PR00421 Thioredoxin family signature 28 37 2.1E-6 T 16-09-2016 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 PRINTS PR00421 Thioredoxin family signature 68 79 2.1E-6 T 16-09-2016 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 PRINTS PR00421 Thioredoxin family signature 20 28 2.1E-6 T 16-09-2016 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 SUPERFAMILY SSF52833 1 104 1.82E-31 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 PANTHER PTHR10438 1 104 7.6E-31 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS22990 3e59b31d807a8d62324da8a03ed1866d 104 PIRSF PIRSF000077 1 104 9.8E-33 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS22725 d68c1765e7fe5baacad9d9b8d2b3236a 398 Pfam PF07730 Histidine kinase 190 253 6.4E-13 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS22725 d68c1765e7fe5baacad9d9b8d2b3236a 398 PANTHER PTHR24421 55 394 4.2E-92 T 16-09-2016 Spa2297_RS22725 d68c1765e7fe5baacad9d9b8d2b3236a 398 SUPERFAMILY SSF55874 275 370 8.86E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22725 d68c1765e7fe5baacad9d9b8d2b3236a 398 PANTHER PTHR24421:SF26 55 394 4.2E-92 T 16-09-2016 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 PANTHER PTHR24032 178 431 2.0E-59 T 16-09-2016 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Pfam PF00149 Calcineurin-like phosphoesterase 192 378 1.4E-13 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 SUPERFAMILY SSF56300 122 402 1.98E-45 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Pfam PF13671 AAA domain 20 147 1.3E-25 T 16-09-2016 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 466 786 8.3E-144 T 16-09-2016 IPR032380 Polynucleotide kinase-phosphatase, ligase domain Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Gene3D G3DSA:3.40.50.300 20 146 1.0E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 SUPERFAMILY SSF52540 20 149 2.27E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 13 849 0.0 T 16-09-2016 IPR024028 Polynucleotide kinase-phosphatase, bacterial Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 791 849 6.0E-31 T 16-09-2016 IPR032390 Polynucleotide kinase-phosphatase, C-terminal Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 SUPERFAMILY SSF56091 674 756 6.91E-13 T 16-09-2016 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 SUPERFAMILY SSF56091 483 605 6.91E-13 T 16-09-2016 Spa2297_RS25100 ab22be1983eed87544f4d5b3d5c14b1b 849 Gene3D G3DSA:3.60.21.10 184 424 4.6E-53 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS27950 44babe0cd5293c188711575aa62aeea6 81 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 81 14.845 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS27950 44babe0cd5293c188711575aa62aeea6 81 PANTHER PTHR38839 10 79 4.7E-28 T 16-09-2016 Spa2297_RS27950 44babe0cd5293c188711575aa62aeea6 81 Pfam PF02467 Transcription factor WhiB 13 76 7.9E-24 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS27950 44babe0cd5293c188711575aa62aeea6 81 PANTHER PTHR38839:SF4 10 79 4.7E-28 T 16-09-2016 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 Hamap MF_00163 Peptide deformylase [def]. 40 206 27.987 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 Pfam PF01327 Polypeptide deformylase 42 196 2.3E-44 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PIRSF PIRSF004749 19 214 6.4E-44 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 SUPERFAMILY SSF56420 40 203 1.28E-52 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PANTHER PTHR10458 29 213 3.0E-59 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PRINTS PR01576 Peptide deformylase signature 164 193 1.2E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PRINTS PR01576 Peptide deformylase signature 71 100 1.2E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PRINTS PR01576 Peptide deformylase signature 145 163 1.2E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 PRINTS PR01576 Peptide deformylase signature 133 144 1.2E-31 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 Gene3D G3DSA:3.90.45.10 42 208 1.5E-57 T 16-09-2016 IPR023635 Peptide deformylase Spa2297_RS22085 bd28bf294461d354407a44c6b000136c 216 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 47 203 1.0E-37 T 16-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 Spa2297_RS32010 ad0429872d9c4547c13d48bb9fe7557a 279 Gene3D G3DSA:3.60.10.10 46 213 2.6E-9 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS32010 ad0429872d9c4547c13d48bb9fe7557a 279 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 48 252 9.6E-16 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS32010 ad0429872d9c4547c13d48bb9fe7557a 279 SUPERFAMILY SSF56219 46 276 4.97E-31 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS10305 c1b926a3e2047512973491fc6d9b62fc 199 Pfam PF01872 RibD C-terminal domain 3 171 1.7E-8 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS10305 c1b926a3e2047512973491fc6d9b62fc 199 Gene3D G3DSA:3.40.430.10 4 192 3.3E-27 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS10305 c1b926a3e2047512973491fc6d9b62fc 199 SUPERFAMILY SSF53597 1 192 1.57E-22 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS10305 c1b926a3e2047512973491fc6d9b62fc 199 PANTHER PTHR38011 2 193 1.9E-15 T 16-09-2016 Spa2297_RS06810 4a7ea9107c421619e15ce8ac6daaeaa0 166 PANTHER PTHR39159:SF1 1 164 1.1E-58 T 16-09-2016 Spa2297_RS06810 4a7ea9107c421619e15ce8ac6daaeaa0 166 Pfam PF04167 Protein of unknown function (DUF402) 62 129 1.6E-18 T 16-09-2016 IPR007295 Domain of unknown function DUF402 Spa2297_RS06810 4a7ea9107c421619e15ce8ac6daaeaa0 166 PANTHER PTHR39159 1 164 1.1E-58 T 16-09-2016 Spa2297_RS06810 4a7ea9107c421619e15ce8ac6daaeaa0 166 SUPERFAMILY SSF159234 55 161 5.75E-14 T 16-09-2016 Spa2297_RS06810 4a7ea9107c421619e15ce8ac6daaeaa0 166 Gene3D G3DSA:2.40.380.10 10 161 4.3E-38 T 16-09-2016 IPR007295 Domain of unknown function DUF402 Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 PANTHER PTHR30061:SF1 3 464 2.2E-40 T 16-09-2016 Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 Gene3D G3DSA:3.40.190.10 194 389 5.2E-32 T 16-09-2016 Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 PANTHER PTHR30061 3 464 2.2E-40 T 16-09-2016 Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 31 479 7.2E-190 T 16-09-2016 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 SUPERFAMILY SSF53850 37 480 3.38E-55 T 16-09-2016 Spa2297_RS25245 c3218e5d85cad0c7647c79125f6b3402 482 Pfam PF13416 Bacterial extracellular solute-binding protein 86 389 3.9E-20 T 16-09-2016 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 Gene3D G3DSA:3.20.20.140 70 390 6.4E-105 T 16-09-2016 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 SUPERFAMILY SSF51338 9 80 7.46E-11 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 PANTHER PTHR11271 8 457 1.5E-250 T 16-09-2016 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 SUPERFAMILY SSF51556 67 382 6.05E-94 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 Pfam PF01979 Amidohydrolase family 64 428 1.5E-61 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 PANTHER PTHR11271:SF37 8 457 1.5E-250 T 16-09-2016 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 Gene3D G3DSA:2.30.40.10 6 69 7.0E-17 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 Gene3D G3DSA:2.30.40.10 391 418 7.0E-17 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26340 06c4d9c03e749112e761fd3c350c8176 462 SUPERFAMILY SSF51338 338 460 6.91E-27 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS30905 8b7905cebf1820c1d5314572af89cb83 319 Gene3D G3DSA:3.40.1190.20 1 310 8.5E-72 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS30905 8b7905cebf1820c1d5314572af89cb83 319 PANTHER PTHR10584 1 310 2.0E-64 T 16-09-2016 Spa2297_RS30905 8b7905cebf1820c1d5314572af89cb83 319 Pfam PF00294 pfkB family carbohydrate kinase 7 303 2.9E-51 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS30905 8b7905cebf1820c1d5314572af89cb83 319 SUPERFAMILY SSF53613 5 306 1.12E-67 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS30905 8b7905cebf1820c1d5314572af89cb83 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS26075 90ce5fd0b24c266797b70196e62606e8 161 Pfam PF04306 Protein of unknown function (DUF456) 21 156 9.6E-27 T 16-09-2016 IPR007403 Protein of unknown function DUF456 Spa2297_RS30705 07c3cfb3dec24b20d444bbe94fe98118 139 Gene3D G3DSA:3.30.450.30 4 127 2.0E-28 T 16-09-2016 Spa2297_RS30705 07c3cfb3dec24b20d444bbe94fe98118 139 SUPERFAMILY SSF103196 2 130 2.44E-32 T 16-09-2016 Spa2297_RS30705 07c3cfb3dec24b20d444bbe94fe98118 139 PANTHER PTHR36222 1 139 3.2E-51 T 16-09-2016 Spa2297_RS30705 07c3cfb3dec24b20d444bbe94fe98118 139 Pfam PF03259 Roadblock/LC7 domain 9 101 6.1E-26 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS30705 07c3cfb3dec24b20d444bbe94fe98118 139 SMART SM00960 9 101 1.4E-26 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS26565 eb0b7283c62b8c63197eecbb02cc4115 287 PANTHER PTHR10992 47 272 1.5E-13 T 16-09-2016 Spa2297_RS26565 eb0b7283c62b8c63197eecbb02cc4115 287 SUPERFAMILY SSF53474 43 271 8.87E-29 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26565 eb0b7283c62b8c63197eecbb02cc4115 287 Gene3D G3DSA:3.40.50.1820 57 270 4.9E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26565 eb0b7283c62b8c63197eecbb02cc4115 287 Pfam PF12697 Alpha/beta hydrolase family 67 217 3.3E-9 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26565 eb0b7283c62b8c63197eecbb02cc4115 287 PANTHER PTHR10992:SF771 47 272 1.5E-13 T 16-09-2016 Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 SUPERFAMILY SSF51556 2 256 1.62E-50 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 PIRSF PIRSF005295 2 259 1.5E-100 T 16-09-2016 IPR012022 Protein of unknown function UCP005295 Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 Gene3D G3DSA:3.20.20.140 4 255 2.9E-34 T 16-09-2016 Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 PANTHER PTHR10060 1 259 2.9E-92 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 Pfam PF01026 TatD related DNase 4 228 2.3E-13 T 16-09-2016 IPR001130 TatD family GO:0016788 Spa2297_RS27395 70d6155d9e51f4a0c9d945c6b56e6d7b 282 PANTHER PTHR10060:SF18 1 259 2.9E-92 T 16-09-2016 Spa2297_RS26310 a584a92bddbb0b6f31a0925a31e94db3 84 SUPERFAMILY SSF89957 1 73 2.83E-7 T 16-09-2016 IPR029756 MTH1187/YkoF-like Spa2297_RS26310 a584a92bddbb0b6f31a0925a31e94db3 84 Gene3D G3DSA:3.30.70.930 3 79 4.1E-6 T 16-09-2016 IPR029756 MTH1187/YkoF-like Spa2297_RS27110 01a9a354c0b1e6ef610e079b35434fe0 272 SUPERFAMILY SSF53335 10 223 1.47E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27110 01a9a354c0b1e6ef610e079b35434fe0 272 Pfam PF13847 Methyltransferase domain 40 155 7.6E-28 T 16-09-2016 IPR025714 Methyltransferase domain Spa2297_RS27110 01a9a354c0b1e6ef610e079b35434fe0 272 PANTHER PTHR10108 33 250 5.6E-102 T 16-09-2016 Spa2297_RS27110 01a9a354c0b1e6ef610e079b35434fe0 272 PANTHER PTHR10108:SF815 33 250 5.6E-102 T 16-09-2016 Spa2297_RS27110 01a9a354c0b1e6ef610e079b35434fe0 272 Gene3D G3DSA:3.40.50.150 9 265 5.8E-47 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 SUPERFAMILY SSF143800 1 80 2.59E-20 T 16-09-2016 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.403 T 16-09-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 PANTHER PTHR33280 1 79 3.9E-37 T 16-09-2016 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.6E-18 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 PANTHER PTHR33280:SF3 1 79 3.9E-37 T 16-09-2016 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 Pfam PF01197 Ribosomal protein L31 1 79 2.3E-27 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.3E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.3E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS04110 6188db146347437a77226f81a8be0d40 93 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.3E-16 T 16-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 SMART SM00866 105 244 1.3E-31 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 2.0E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 2.0E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 PANTHER PTHR11751 134 157 6.0E-15 T 16-09-2016 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 PANTHER PTHR11751 38 88 6.0E-15 T 16-09-2016 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 SUPERFAMILY SSF46785 21 94 2.72E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 Pfam PF07702 UTRA domain 106 243 3.0E-30 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 SMART SM00345 29 85 1.9E-9 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 Gene3D G3DSA:3.40.1410.10 85 250 4.1E-43 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 85 1.9E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 SUPERFAMILY SSF64288 77 250 6.6E-44 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS12190 1bc2c2f9d00dea9aa859674d04de426a 251 Gene3D G3DSA:1.10.10.10 20 84 3.0E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07565 8198faa33bb3b5a829bc1018a1e44b87 269 PANTHER PTHR10366:SF476 6 217 3.3E-71 T 16-09-2016 Spa2297_RS07565 8198faa33bb3b5a829bc1018a1e44b87 269 SUPERFAMILY SSF51735 1 231 2.5E-47 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07565 8198faa33bb3b5a829bc1018a1e44b87 269 Gene3D G3DSA:3.40.50.720 4 217 2.0E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS07565 8198faa33bb3b5a829bc1018a1e44b87 269 PANTHER PTHR10366 6 217 3.3E-71 T 16-09-2016 Spa2297_RS07565 8198faa33bb3b5a829bc1018a1e44b87 269 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 167 2.9E-22 T 16-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 Spa2297_RS07470 8d2fcc303a97fd5342ba97e8352bcece 202 PANTHER PTHR35332 3 201 5.7E-56 T 16-09-2016 Spa2297_RS07470 8d2fcc303a97fd5342ba97e8352bcece 202 Pfam PF07081 Protein of unknown function (DUF1349) 20 192 6.2E-40 T 16-09-2016 IPR009784 Protein of unknown function DUF1349 Spa2297_RS07470 8d2fcc303a97fd5342ba97e8352bcece 202 PANTHER PTHR35332:SF2 3 201 5.7E-56 T 16-09-2016 Spa2297_RS07470 8d2fcc303a97fd5342ba97e8352bcece 202 Gene3D G3DSA:2.60.120.200 53 191 6.0E-9 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS07470 8d2fcc303a97fd5342ba97e8352bcece 202 SUPERFAMILY SSF49899 52 191 7.12E-14 T 16-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain Spa2297_RS25075 bfac3446a260d98613ecc5a83d71f36b 384 SUPERFAMILY SSF52540 39 63 5.31E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25075 bfac3446a260d98613ecc5a83d71f36b 384 SUPERFAMILY SSF52540 274 359 5.31E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25075 bfac3446a260d98613ecc5a83d71f36b 384 Gene3D G3DSA:3.40.1140.10 19 116 3.7E-7 T 16-09-2016 Spa2297_RS25075 bfac3446a260d98613ecc5a83d71f36b 384 Gene3D G3DSA:3.40.1140.10 290 357 3.7E-7 T 16-09-2016 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 Gene3D G3DSA:2.60.40.10 32 124 1.4E-15 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 PANTHER PTHR22298 195 391 4.3E-27 T 16-09-2016 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 Pfam PF00759 Glycosyl hydrolase family 9 140 622 5.2E-72 T 16-09-2016 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 Pfam PF02927 Cellulase N-terminal ig-like domain 38 118 3.7E-14 T 16-09-2016 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 SUPERFAMILY SSF48208 594 624 9.07E-66 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 SUPERFAMILY SSF48208 136 562 9.07E-66 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 SUPERFAMILY SSF81296 32 121 1.96E-14 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 PANTHER PTHR22298:SF39 195 391 4.3E-27 T 16-09-2016 Spa2297_RS00925 d59e35af5fa2f37c6b0dbff2f59a83a0 629 Gene3D G3DSA:1.50.10.10 140 623 1.5E-66 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS25235 f4a5ce627764e08892cf005dc3f2a36b 318 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 217 279 3.7E-7 T 16-09-2016 Spa2297_RS25235 f4a5ce627764e08892cf005dc3f2a36b 318 SUPERFAMILY SSF69318 83 313 2.22E-19 T 16-09-2016 Spa2297_RS25235 f4a5ce627764e08892cf005dc3f2a36b 318 Gene3D G3DSA:2.115.10.10 80 230 2.3E-9 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS25235 f4a5ce627764e08892cf005dc3f2a36b 318 Gene3D G3DSA:2.115.10.10 231 318 1.6E-14 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS29320 b36ebcd1b9504841b2a362caf0ea1357 331 Gene3D G3DSA:1.20.140.10 182 304 1.7E-5 T 16-09-2016 Spa2297_RS29320 b36ebcd1b9504841b2a362caf0ea1357 331 Gene3D G3DSA:2.40.110.10 79 170 8.6E-12 T 16-09-2016 Spa2297_RS29320 b36ebcd1b9504841b2a362caf0ea1357 331 SUPERFAMILY SSF56645 22 172 3.14E-16 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 Gene3D G3DSA:1.10.3720.10 61 270 9.9E-41 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 64 161 1.7E-15 T 16-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 SUPERFAMILY SSF161098 63 270 2.35E-36 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 PANTHER PTHR30614 9 274 2.8E-69 T 16-09-2016 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 PANTHER PTHR30614:SF0 9 274 2.8E-69 T 16-09-2016 Spa2297_RS24430 1dea9dbc6f5084a0f2f3187b84e6f125 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 270 1.1E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS19505 94047db884b5ad57d131d983b9db4c60 196 SMART SM00860 29 155 3.9E-6 T 16-09-2016 IPR018958 SMI1/KNR4-like domain Spa2297_RS19505 94047db884b5ad57d131d983b9db4c60 196 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 36 154 2.7E-9 T 16-09-2016 IPR018958 SMI1/KNR4-like domain Spa2297_RS19505 94047db884b5ad57d131d983b9db4c60 196 SUPERFAMILY SSF160631 23 158 1.28E-14 T 16-09-2016 Spa2297_RS12730 c07f1a63efe7912fa14fb18bc9efb7b8 94 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 1.2E-32 T 16-09-2016 IPR021400 Protein of unknown function DUF3039 Spa2297_RS30420 0f15c1b9a65c8878b5987cf118f4b057 254 PANTHER PTHR36852:SF1 1 250 5.1E-75 T 16-09-2016 Spa2297_RS30420 0f15c1b9a65c8878b5987cf118f4b057 254 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 17 245 1.3E-52 T 16-09-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 Spa2297_RS30420 0f15c1b9a65c8878b5987cf118f4b057 254 PANTHER PTHR36852 1 250 5.1E-75 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PANTHER PTHR11922 12 523 2.4E-269 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 9.3E-8 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 9.3E-8 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 58 67 9.3E-8 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PANTHER PTHR11922:SF2 12 523 2.4E-269 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 SUPERFAMILY SSF52402 190 446 7.94E-59 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 SUPERFAMILY SSF54810 405 526 4.18E-47 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Pfam PF02540 NAD synthase 217 289 6.5E-7 T 16-09-2016 IPR022310 NAD/GMP synthase Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Gene3D G3DSA:3.40.50.620 220 400 4.5E-57 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 14 196 3.4E-71 T 16-09-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 11 526 53.612 T 16-09-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 526 1.3E-147 T 16-09-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 14 28 1.2E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 55 69 1.2E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 85 101 1.2E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Pfam PF00958 GMP synthase C terminal domain 433 525 9.2E-39 T 16-09-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Gene3D G3DSA:3.30.300.10 401 526 6.7E-49 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Gene3D G3DSA:3.40.50.880 11 219 6.7E-56 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00097 Anthranilate synthase component II signature 174 187 1.1E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00097 Anthranilate synthase component II signature 58 67 1.1E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 PRINTS PR00097 Anthranilate synthase component II signature 85 96 1.1E-5 T 16-09-2016 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 Pfam PF00117 Glutamine amidotransferase class-I 16 196 9.4E-40 T 16-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 Spa2297_RS20180 bab25332d338f40168fd946fb6fdc919 526 SUPERFAMILY SSF52317 14 205 1.19E-50 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 23 264 1.0E-69 T 16-09-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 SUPERFAMILY SSF53335 22 257 5.07E-56 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 PANTHER PTHR13600 19 259 6.2E-57 T 16-09-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 Gene3D G3DSA:3.40.50.150 75 218 4.2E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 PANTHER PTHR13600:SF12 19 259 6.2E-57 T 16-09-2016 Spa2297_RS04665 83a9b7d51a138f1bfc3ee56bfc19b689 291 Pfam PF04072 Leucine carboxyl methyltransferase 25 194 5.7E-45 T 16-09-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 134 2.8E-50 T 16-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 Pfam PF01641 SelR domain 11 131 1.5E-52 T 16-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 Gene3D G3DSA:2.170.150.20 2 134 1.1E-60 T 16-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 PANTHER PTHR10173:SF18 5 134 1.5E-64 T 16-09-2016 Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 PANTHER PTHR10173 5 134 1.5E-64 T 16-09-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 Spa2297_RS25505 7fe2bb827a08755af7fe94fa0fd12edf 135 SUPERFAMILY SSF51316 6 134 2.41E-55 T 16-09-2016 IPR011057 Mss4-like Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 Hamap MF_00799 UPF0336 protein . 1 148 36.398 T 16-09-2016 IPR016709 Uncharacterised protein family UPF0336 Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 PANTHER PTHR13078:SF52 5 147 6.5E-36 T 16-09-2016 Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 Gene3D G3DSA:3.10.129.10 1 148 8.5E-41 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 PANTHER PTHR13078 5 147 6.5E-36 T 16-09-2016 Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.2E-34 T 16-09-2016 Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 PIRSF PIRSF018072 1 150 6.2E-60 T 16-09-2016 IPR016709 Uncharacterised protein family UPF0336 Spa2297_RS19565 571108ecb02d839bac9e737f72ba26b7 150 SUPERFAMILY SSF54637 7 147 8.61E-40 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS04875 d1ff2314925b3a95e08394f304e13fa3 291 PANTHER PTHR30622:SF4 1 285 1.3E-143 T 16-09-2016 Spa2297_RS04875 d1ff2314925b3a95e08394f304e13fa3 291 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 277 17.647 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS04875 d1ff2314925b3a95e08394f304e13fa3 291 Pfam PF02673 Bacitracin resistance protein BacA 7 272 2.4E-76 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS04875 d1ff2314925b3a95e08394f304e13fa3 291 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 270 4.1E-74 T 16-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spa2297_RS04875 d1ff2314925b3a95e08394f304e13fa3 291 PANTHER PTHR30622 1 285 1.3E-143 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 Pfam PF13671 AAA domain 120 254 9.4E-7 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 Gene3D G3DSA:3.40.50.300 120 293 3.0E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 SUPERFAMILY SSF52540 120 291 1.56E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 PRINTS PR01217 Proline rich extensin signature 3 19 3.3E-9 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 PRINTS PR01217 Proline rich extensin signature 44 65 3.3E-9 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 PRINTS PR01217 Proline rich extensin signature 30 42 3.3E-9 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 PRINTS PR01217 Proline rich extensin signature 93 110 3.3E-9 T 16-09-2016 Spa2297_RS05635 4988ad9fcfecbc7b11655024b62deaa0 299 PRINTS PR01217 Proline rich extensin signature 66 82 3.3E-9 T 16-09-2016 Spa2297_RS23690 4520e0d205a5bf1e089e0e465b5be864 483 PANTHER PTHR31806:SF2 3 475 4.0E-225 T 16-09-2016 Spa2297_RS23690 4520e0d205a5bf1e089e0e465b5be864 483 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 18 445 1.5E-112 T 16-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS23690 4520e0d205a5bf1e089e0e465b5be864 483 PIRSF PIRSF002744 1 472 1.7E-112 T 16-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 Spa2297_RS23690 4520e0d205a5bf1e089e0e465b5be864 483 PANTHER PTHR31806 3 475 4.0E-225 T 16-09-2016 Spa2297_RS27465 9ac4e7b2dbd6ca5c62316b7677ca5e4e 352 Gene3D G3DSA:2.40.10.10 16 78 2.3E-4 T 16-09-2016 Spa2297_RS27465 9ac4e7b2dbd6ca5c62316b7677ca5e4e 352 Pfam PF13365 Trypsin-like peptidase domain 20 185 2.6E-11 T 16-09-2016 Spa2297_RS27465 9ac4e7b2dbd6ca5c62316b7677ca5e4e 352 SUPERFAMILY SSF50494 18 194 1.57E-15 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 PANTHER PTHR23517 2 420 6.0E-156 T 16-09-2016 Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 Gene3D G3DSA:1.20.1250.20 223 408 2.0E-20 T 16-09-2016 Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 PANTHER PTHR23517:SF3 2 420 6.0E-156 T 16-09-2016 Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 Pfam PF07690 Major Facilitator Superfamily 25 251 7.6E-31 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 SUPERFAMILY SSF103473 18 400 3.01E-61 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS15150 89ef4402c1d84e32cc6f8cf9c2dc3d41 426 Gene3D G3DSA:1.20.1250.20 21 200 7.1E-29 T 16-09-2016 Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 PANTHER PTHR24220:SF309 4 240 5.5E-84 T 16-09-2016 Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 SMART SM00382 27 211 1.4E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 Pfam PF00005 ABC transporter 18 167 1.6E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 PANTHER PTHR24220 4 240 5.5E-84 T 16-09-2016 Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 Gene3D G3DSA:3.40.50.300 6 239 1.1E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS30480 6567c39459947dc3e3905222144675ee 257 SUPERFAMILY SSF52540 3 225 4.82E-61 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 SUPERFAMILY SSF52788 1 154 1.7E-49 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 152 5.9E-47 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PANTHER PTHR11717:SF7 4 158 2.7E-49 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 126 141 2.5E-26 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 2.5E-26 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 105 118 2.5E-26 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 2.5E-26 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.5E-26 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 SMART SM00226 3 154 2.1E-58 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 PANTHER PTHR11717 4 158 2.7E-49 T 16-09-2016 Spa2297_RS16365 d9e997b85dbeb7d2ef652ad39d91a1e3 164 Gene3D G3DSA:3.40.50.270 1 158 1.1E-53 T 16-09-2016 Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 Pfam PF08291 Peptidase M15 117 229 3.1E-32 T 16-09-2016 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 SUPERFAMILY SSF55166 116 242 2.31E-21 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 SUPERFAMILY SSF47090 35 106 3.4E-18 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 Gene3D G3DSA:3.30.1380.10 117 239 9.3E-29 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 Pfam PF01471 Putative peptidoglycan binding domain 48 104 2.0E-12 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS23105 3711ba099ef884094d050c01106efb56 244 Gene3D G3DSA:1.10.101.10 38 108 8.1E-20 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PIRSF PIRSF001553 1 292 1.1E-114 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 156 183 - T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 5.5E-123 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 Gene3D G3DSA:3.40.50.720 3 123 9.7E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 Gene3D G3DSA:3.40.50.261 124 286 4.6E-66 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 SUPERFAMILY SSF52210 127 287 3.14E-46 T 16-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 3.9E-33 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 3.9E-33 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 3.9E-33 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 3.9E-33 T 16-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 Pfam PF00549 CoA-ligase 155 273 2.6E-12 T 16-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 SUPERFAMILY SSF51735 1 126 8.8E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 16-09-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 PANTHER PTHR11117 1 290 1.1E-142 T 16-09-2016 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 Pfam PF02629 CoA binding domain 6 103 3.6E-25 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS27440 8f6339e1b857be5a5641da6705c1692a 300 SMART SM00881 4 104 4.7E-26 T 16-09-2016 IPR003781 CoA-binding GO:0048037 Spa2297_RS27020 5fdf899ae0a5f1c7c4f052657a57f523 190 Gene3D G3DSA:3.40.630.30 8 184 4.9E-41 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS27020 5fdf899ae0a5f1c7c4f052657a57f523 190 PANTHER PTHR13256:SF24 11 185 3.3E-55 T 16-09-2016 Spa2297_RS27020 5fdf899ae0a5f1c7c4f052657a57f523 190 PANTHER PTHR13256 11 185 3.3E-55 T 16-09-2016 Spa2297_RS27020 5fdf899ae0a5f1c7c4f052657a57f523 190 Pfam PF13302 Acetyltransferase (GNAT) domain 14 159 1.0E-16 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS27020 5fdf899ae0a5f1c7c4f052657a57f523 190 SUPERFAMILY SSF55729 11 183 2.39E-30 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11725 e21b17f11f56e3d33a2d007484cc093c 522 PANTHER PTHR33744:SF3 23 516 2.9E-39 T 16-09-2016 Spa2297_RS11725 e21b17f11f56e3d33a2d007484cc093c 522 Pfam PF13556 PucR C-terminal helix-turn-helix domain 459 516 3.4E-20 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS11725 e21b17f11f56e3d33a2d007484cc093c 522 Pfam PF07905 Purine catabolism regulatory protein-like family 29 148 1.2E-23 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS11725 e21b17f11f56e3d33a2d007484cc093c 522 PANTHER PTHR33744 23 516 2.9E-39 T 16-09-2016 Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 PANTHER PTHR11935:SF8 1 220 4.5E-57 T 16-09-2016 Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 PANTHER PTHR11935 1 220 4.5E-57 T 16-09-2016 Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 SMART SM00849 12 202 3.5E-38 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 Gene3D G3DSA:3.60.15.10 9 220 7.8E-51 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 5.6E-28 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS05710 1714f0879fe0a07da3ebc75531cab28f 235 SUPERFAMILY SSF56281 6 223 1.76E-48 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 PANTHER PTHR21090 375 441 4.3E-134 T 16-09-2016 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 PANTHER PTHR21090 4 358 4.3E-134 T 16-09-2016 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 Gene3D G3DSA:3.65.10.10 27 230 1.8E-52 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 433 1.9E-58 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9 441 2.6E-130 T 16-09-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 SUPERFAMILY SSF55205 9 442 3.27E-111 T 16-09-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Spa2297_RS12740 84338a409e7509d2099a4464b1f92cef 448 Gene3D G3DSA:3.65.10.10 231 441 3.3E-48 T 16-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 Spa2297_RS29970 34738142d7045b659a8999a8488d8170 192 SUPERFAMILY SSF52499 8 188 8.37E-50 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS29970 34738142d7045b659a8999a8488d8170 192 PANTHER PTHR11080 9 190 1.9E-65 T 16-09-2016 Spa2297_RS29970 34738142d7045b659a8999a8488d8170 192 Gene3D G3DSA:3.40.50.850 9 185 2.0E-52 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS29970 34738142d7045b659a8999a8488d8170 192 Pfam PF00857 Isochorismatase family 10 183 7.3E-41 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS29970 34738142d7045b659a8999a8488d8170 192 PANTHER PTHR11080:SF37 9 190 1.9E-65 T 16-09-2016 Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 Pfam PF00083 Sugar (and other) transporter 24 422 1.5E-25 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 SUPERFAMILY SSF103473 20 435 6.93E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 PANTHER PTHR23508 20 434 3.1E-134 T 16-09-2016 Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 Gene3D G3DSA:1.20.1250.20 256 430 5.6E-16 T 16-09-2016 Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 Gene3D G3DSA:1.20.1250.20 21 237 9.8E-23 T 16-09-2016 Spa2297_RS06685 ce41caa8d1a55d32e4cc8fbe0dfc9031 441 PANTHER PTHR23508:SF1 20 434 3.1E-134 T 16-09-2016 Spa2297_RS29585 be2a0036f9cba4025e832b4df59d3e68 285 SUPERFAMILY SSF52540 28 274 2.7E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29585 be2a0036f9cba4025e832b4df59d3e68 285 Gene3D G3DSA:3.40.50.300 31 214 5.1E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29585 be2a0036f9cba4025e832b4df59d3e68 285 SMART SM00382 33 197 1.9E-7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29585 be2a0036f9cba4025e832b4df59d3e68 285 PANTHER PTHR22908 17 259 2.1E-66 T 16-09-2016 Spa2297_RS29585 be2a0036f9cba4025e832b4df59d3e68 285 Pfam PF07728 AAA domain (dynein-related subfamily) 37 186 4.0E-12 T 16-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 SMART SM00644 84 213 2.4E-45 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 SUPERFAMILY SSF55846 82 227 1.57E-40 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 Gene3D G3DSA:3.40.80.10 71 228 2.4E-42 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 95 214 2.5E-22 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 PANTHER PTHR30417:SF1 23 241 5.6E-69 T 16-09-2016 Spa2297_RS23215 bd271219c1bb86504026c5e1dd11d076 245 PANTHER PTHR30417 23 241 5.6E-69 T 16-09-2016 Spa2297_RS11130 b7ba5e34f90424ce3839d3e2ccc35716 485 Pfam PF00324 Amino acid permease 32 474 5.8E-116 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS11130 b7ba5e34f90424ce3839d3e2ccc35716 485 PIRSF PIRSF006060 6 484 9.0E-73 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS11130 b7ba5e34f90424ce3839d3e2ccc35716 485 ProSitePatterns PS00218 Amino acid permeases signature. 57 87 - T 16-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 Spa2297_RS11130 b7ba5e34f90424ce3839d3e2ccc35716 485 PANTHER PTHR11785 22 479 1.5E-235 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS11130 b7ba5e34f90424ce3839d3e2ccc35716 485 PANTHER PTHR11785:SF24 22 479 1.5E-235 T 16-09-2016 Spa2297_RS30370 f97e67dc1862d347888ea7efbd889ff9 328 PANTHER PTHR30193 13 328 4.3E-127 T 16-09-2016 Spa2297_RS30370 f97e67dc1862d347888ea7efbd889ff9 328 Gene3D G3DSA:1.10.3720.10 33 313 2.9E-43 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30370 f97e67dc1862d347888ea7efbd889ff9 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 311 2.5E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30370 f97e67dc1862d347888ea7efbd889ff9 328 PANTHER PTHR30193:SF2 13 328 4.3E-127 T 16-09-2016 Spa2297_RS30370 f97e67dc1862d347888ea7efbd889ff9 328 SUPERFAMILY SSF161098 87 312 8.24E-41 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS07280 403b1cdcc340bf26f77e83e881e14100 335 Pfam PF05425 Copper resistance protein D 230 325 4.2E-12 T 16-09-2016 IPR008457 Copper resistance protein D GO:0016021 Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 113 2.1E-20 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 Gene3D G3DSA:3.30.360.10 157 287 4.4E-14 T 16-09-2016 Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 SUPERFAMILY SSF55347 143 243 6.05E-11 T 16-09-2016 Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 SUPERFAMILY SSF51735 2 131 4.94E-35 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 Gene3D G3DSA:3.40.50.720 1 127 1.4E-33 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30135 da89fb30a7aba5296f4a87636da26868 295 PANTHER PTHR22604 1 243 2.3E-47 T 16-09-2016 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 PANTHER PTHR30055:SF92 3 231 5.3E-73 T 16-09-2016 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 Gene3D G3DSA:1.10.357.10 7 195 2.6E-28 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 SUPERFAMILY SSF46689 12 89 5.13E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 PANTHER PTHR30055 3 231 5.3E-73 T 16-09-2016 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 8.4E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.6E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS03685 90cc77fb207934fcd47096030f9f6f69 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.6E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS19660 1be7d62d38d9f48b007e2a1a4c386291 341 SUPERFAMILY SSF53448 14 190 5.2E-35 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS19660 1be7d62d38d9f48b007e2a1a4c386291 341 Pfam PF00535 Glycosyl transferase family 2 16 178 2.3E-29 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS19660 1be7d62d38d9f48b007e2a1a4c386291 341 Gene3D G3DSA:3.90.550.10 15 143 7.1E-24 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS19660 1be7d62d38d9f48b007e2a1a4c386291 341 PANTHER PTHR10859 3 324 2.7E-132 T 16-09-2016 Spa2297_RS19660 1be7d62d38d9f48b007e2a1a4c386291 341 PANTHER PTHR10859:SF49 3 324 2.7E-132 T 16-09-2016 Spa2297_RS00975 5607d3534a9f9502786b2a1b4a23d65b 293 PANTHER PTHR23344:SF20 44 292 3.7E-71 T 16-09-2016 Spa2297_RS00975 5607d3534a9f9502786b2a1b4a23d65b 293 Gene3D G3DSA:3.20.20.190 25 291 2.2E-68 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS00975 5607d3534a9f9502786b2a1b4a23d65b 293 SUPERFAMILY SSF51695 43 292 1.99E-68 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS00975 5607d3534a9f9502786b2a1b4a23d65b 293 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 49 289 7.1E-45 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS00975 5607d3534a9f9502786b2a1b4a23d65b 293 PANTHER PTHR23344 44 292 3.7E-71 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 PANTHER PTHR11559 1 497 2.6E-142 T 16-09-2016 Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 Pfam PF00135 Carboxylesterase family 11 482 2.0E-87 T 16-09-2016 IPR002018 Carboxylesterase, type B Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 Gene3D G3DSA:3.40.50.1820 9 497 7.8E-123 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 SUPERFAMILY SSF53474 11 497 3.14E-107 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 PANTHER PTHR11559:SF142 1 497 2.6E-142 T 16-09-2016 Spa2297_RS14795 cdfa742397958eb55174b62314f7d4da 511 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 16-09-2016 IPR019826 Carboxylesterase type B, active site Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 333 8.3E-80 T 16-09-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PANTHER PTHR10890:SF5 1 381 1.8E-270 T 16-09-2016 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 SUPERFAMILY SSF52374 32 333 2.33E-66 T 16-09-2016 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 7.5E-205 T 16-09-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PANTHER PTHR10890 1 381 1.8E-270 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.548 T 16-09-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 1.5E-18 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 1.5E-18 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 1.5E-18 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 1.5E-18 T 16-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spa2297_RS06465 62c4aa4c2911973b30f960ec9f64f396 409 Gene3D G3DSA:3.40.50.620 37 326 8.7E-73 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS31955 9167d93e2e9b166da1dcf682d5dbed13 160 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 44 57 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS31955 9167d93e2e9b166da1dcf682d5dbed13 160 PANTHER PTHR35344:SF1 1 80 1.3E-22 T 16-09-2016 Spa2297_RS31955 9167d93e2e9b166da1dcf682d5dbed13 160 Pfam PF00741 Gas vesicle protein 10 48 2.2E-15 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS31955 9167d93e2e9b166da1dcf682d5dbed13 160 PANTHER PTHR35344 1 80 1.3E-22 T 16-09-2016 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 1.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 1.1E-7 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 SUPERFAMILY SSF46689 38 110 5.64E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 94 4.6E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 PANTHER PTHR30055 31 217 2.6E-72 T 16-09-2016 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 Gene3D G3DSA:1.10.357.10 98 223 7.9E-37 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 PANTHER PTHR30055:SF53 31 217 2.6E-72 T 16-09-2016 Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 SUPERFAMILY SSF48498 116 223 1.38E-27 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS28710 c6ffec814eeabf2e1ba519f216d06a9e 224 Gene3D G3DSA:1.10.10.60 38 96 1.3E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS32040 25fd889bd834a6b6ebdcc7db11d1ae36 369 SUPERFAMILY SSF53850 52 358 3.07E-26 T 16-09-2016 Spa2297_RS32040 25fd889bd834a6b6ebdcc7db11d1ae36 369 Gene3D G3DSA:3.40.190.10 52 139 1.6E-11 T 16-09-2016 Spa2297_RS32040 25fd889bd834a6b6ebdcc7db11d1ae36 369 Pfam PF01547 Bacterial extracellular solute-binding protein 52 152 1.0E-6 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS24000 fa377da363fbcfae0fdfca3e24322a6d 206 Pfam PF08719 Domain of unknown function (DUF1768) 60 205 2.8E-52 T 16-09-2016 IPR012816 Conserved hypothetical protein CHP02464 Spa2297_RS24000 fa377da363fbcfae0fdfca3e24322a6d 206 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 47 204 3.7E-48 T 16-09-2016 IPR012816 Conserved hypothetical protein CHP02464 Spa2297_RS24000 fa377da363fbcfae0fdfca3e24322a6d 206 PANTHER PTHR11079 113 194 6.8E-40 T 16-09-2016 Spa2297_RS24000 fa377da363fbcfae0fdfca3e24322a6d 206 PANTHER PTHR11079:SF69 113 194 6.8E-40 T 16-09-2016 Spa2297_RS24000 fa377da363fbcfae0fdfca3e24322a6d 206 SUPERFAMILY SSF143990 37 205 2.35E-48 T 16-09-2016 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 Pfam PF01425 Amidase 25 447 8.4E-105 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 SUPERFAMILY SSF75304 1 453 4.06E-137 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 PANTHER PTHR11895 1 456 8.1E-151 T 16-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 ProSitePatterns PS00571 Amidases signature. 154 185 - T 16-09-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 PANTHER PTHR11895:SF66 1 456 8.1E-151 T 16-09-2016 Spa2297_RS12065 2d64050bbfcadc03da35f8b4123fe867 459 Gene3D G3DSA:3.90.1300.10 1 454 9.6E-137 T 16-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.4E-38 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.4E-38 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.4E-38 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.4E-38 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.8E-47 T 16-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 16-09-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.2E-54 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.93 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 16-09-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 SUPERFAMILY SSF54686 1 135 3.4E-55 T 16-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 Gene3D G3DSA:3.90.1170.10 23 136 3.5E-52 T 16-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19830 94e87c15ee519c1b2cef344032302194 139 PANTHER PTHR12220 1 135 2.2E-69 T 16-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Spa2297_RS01515 4c419a6766ccd60234562e1c7613a54f 387 Pfam PF04486 SchA/CurD like domain 149 260 2.2E-45 T 16-09-2016 IPR007575 SchA/CurD-like domain Spa2297_RS01515 4c419a6766ccd60234562e1c7613a54f 387 Pfam PF03992 Antibiotic biosynthesis monooxygenase 32 104 4.4E-14 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS01515 4c419a6766ccd60234562e1c7613a54f 387 Gene3D G3DSA:3.30.70.900 36 122 1.8E-14 T 16-09-2016 Spa2297_RS01515 4c419a6766ccd60234562e1c7613a54f 387 SUPERFAMILY SSF54909 32 121 9.3E-19 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS06540 ddc954787e062f6682bac890fd01db5d 123 PANTHER PTHR33747 10 116 1.3E-15 T 16-09-2016 Spa2297_RS06540 ddc954787e062f6682bac890fd01db5d 123 SUPERFAMILY SSF54427 25 121 1.64E-32 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS06540 ddc954787e062f6682bac890fd01db5d 123 Gene3D G3DSA:3.10.450.50 5 121 6.5E-40 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS06540 ddc954787e062f6682bac890fd01db5d 123 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 2 120 28.859 T 16-09-2016 IPR023006 Uncharacterised protein family UPF0225 Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 Gene3D G3DSA:3.40.50.720 1 251 7.3E-78 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PANTHER PTHR24322:SF330 157 188 1.7E-48 T 16-09-2016 Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PANTHER PTHR24322:SF330 12 141 1.7E-48 T 16-09-2016 Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PANTHER PTHR24322 157 188 1.7E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PANTHER PTHR24322 12 141 1.7E-48 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-40 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.1E-57 T 16-09-2016 Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.5E-11 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS29245 9c3bfd1b58c13afdb0624af7245121b8 253 SUPERFAMILY SSF51735 1 252 1.97E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.437 T 16-09-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UniPathway: UPA00997 Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 PANTHER PTHR11599 24 237 2.0E-64 T 16-09-2016 Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 7.0E-117 T 16-09-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UniPathway: UPA00997 Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 PANTHER PTHR11599:SF38 24 237 2.0E-64 T 16-09-2016 Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 Pfam PF00227 Proteasome subunit 25 191 3.3E-28 T 16-09-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 SUPERFAMILY SSF56235 10 230 3.05E-44 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS06370 3685569d00c2f831fd696fa5de41c3e3 255 Gene3D G3DSA:3.60.20.10 3 233 2.2E-84 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 SUPERFAMILY SSF46689 15 95 1.6E-21 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 6.2E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.2E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 SUPERFAMILY SSF48498 91 232 3.2E-48 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 PANTHER PTHR30055:SF24 7 245 1.2E-118 T 16-09-2016 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 6.4E-19 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 PANTHER PTHR30055 7 245 1.2E-118 T 16-09-2016 Spa2297_RS20480 8f0bdea38950f840043dfdd58e786f19 247 Gene3D G3DSA:1.10.357.10 16 206 5.2E-36 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 PANTHER PTHR10108 24 148 9.5E-56 T 16-09-2016 Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 PANTHER PTHR10108:SF893 24 148 9.5E-56 T 16-09-2016 Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 PIRSF PIRSF034653 1 248 3.0E-111 T 16-09-2016 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 PANTHER PTHR10108 174 248 9.5E-56 T 16-09-2016 Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 SUPERFAMILY SSF53335 8 247 2.71E-41 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 Gene3D G3DSA:3.40.50.150 10 246 2.5E-48 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 Pfam PF13649 Methyltransferase domain 40 134 1.8E-9 T 16-09-2016 Spa2297_RS00145 3cdf0211bd6d0d7cada9fb1742169f68 248 PANTHER PTHR10108:SF893 174 248 9.5E-56 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 PANTHER PTHR12526 2 60 7.1E-66 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 PANTHER PTHR12526 76 416 7.1E-66 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 Pfam PF13439 Glycosyltransferase Family 4 13 189 7.2E-9 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 Gene3D G3DSA:3.40.50.2000 197 355 6.4E-25 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 SUPERFAMILY SSF53756 7 377 4.71E-67 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 Pfam PF00534 Glycosyl transferases group 1 198 353 3.9E-36 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 PANTHER PTHR12526:SF374 2 60 7.1E-66 T 16-09-2016 Spa2297_RS25325 90f5793a18b3486659db7ba6d99f5893 697 PANTHER PTHR12526:SF374 76 416 7.1E-66 T 16-09-2016 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 SMART SM00825 Beta-ketoacyl synthase 8 421 3.0E-13 T 16-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 382 7.8E-31 T 16-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 SUPERFAMILY SSF53901 227 429 6.91E-61 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 Gene3D G3DSA:3.40.47.10 277 429 2.8E-47 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 PIRSF PIRSF000447 3 430 1.2E-140 T 16-09-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 260 4.9E-54 T 16-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 PANTHER PTHR11712 5 429 2.5E-155 T 16-09-2016 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 Gene3D G3DSA:3.40.47.10 10 271 9.8E-68 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS10050 a6e2906c7c9e1631371a807184dfdb2c 430 SUPERFAMILY SSF53901 6 265 1.68E-67 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS26905 59cd2912c16532ad7c0f82df16441a75 271 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 198 1.8E-34 T 16-09-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 Spa2297_RS26905 59cd2912c16532ad7c0f82df16441a75 271 PANTHER PTHR15362 19 170 1.7E-19 T 16-09-2016 Spa2297_RS26905 59cd2912c16532ad7c0f82df16441a75 271 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 100 1.2E-11 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS26905 59cd2912c16532ad7c0f82df16441a75 271 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 79 100 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS26905 59cd2912c16532ad7c0f82df16441a75 271 PANTHER PTHR15362:SF2 19 170 1.7E-19 T 16-09-2016 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PANTHER PTHR33794:SF2 22 676 2.9E-259 T 16-09-2016 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PANTHER PTHR33794 22 676 2.9E-259 T 16-09-2016 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 393 404 9.6E-19 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 336 356 9.6E-19 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 372 388 9.6E-19 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 460 476 9.6E-19 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Gene3D G3DSA:2.60.120.260 583 682 9.7E-16 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 384 558 4.9E-52 T 16-09-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 235 381 1.8E-48 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Gene3D G3DSA:1.10.390.10 386 558 6.6E-51 T 16-09-2016 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Pfam PF01483 Proprotein convertase P-domain 602 682 2.0E-19 T 16-09-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 95 137 4.6E-12 T 16-09-2016 IPR011096 FTP domain Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 SUPERFAMILY SSF55486 232 559 2.56E-82 T 16-09-2016 Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 SUPERFAMILY SSF49785 577 682 1.53E-24 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS23035 e881cb075f3895754e70b237df0bd0d1 683 Gene3D G3DSA:3.10.170.10 233 385 3.8E-47 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 SUPERFAMILY SSF55729 6 173 1.86E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 Pfam PF00583 Acetyltransferase (GNAT) family 69 149 5.4E-15 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 PANTHER PTHR23091 6 30 9.2E-19 T 16-09-2016 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 PANTHER PTHR23091 50 161 9.2E-19 T 16-09-2016 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 PANTHER PTHR23091:SF274 50 161 9.2E-19 T 16-09-2016 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 PANTHER PTHR23091:SF274 6 30 9.2E-19 T 16-09-2016 Spa2297_RS26955 f392a90e58442849b3bfc916c6cfb086 175 Gene3D G3DSA:3.40.630.30 6 170 1.3E-45 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS21835 bab0f1a789c5e9afc4233b1f4319d26b 521 Pfam PF11350 Protein of unknown function (DUF3152) 340 519 2.7E-64 T 16-09-2016 IPR022603 Domain of unknown function DUF3152 Spa2297_RS21835 bab0f1a789c5e9afc4233b1f4319d26b 521 SUPERFAMILY SSF55486 377 507 1.19E-13 T 16-09-2016 Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 PANTHER PTHR11670 1 192 1.3E-100 T 16-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.1E-58 T 16-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 Gene3D G3DSA:3.20.19.10 1 187 8.2E-42 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 Pfam PF00694 Aconitase C-terminal domain 1 117 1.9E-25 T 16-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 SUPERFAMILY SSF52016 1 186 1.96E-52 T 16-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 PANTHER PTHR11670:SF27 1 192 1.3E-100 T 16-09-2016 Spa2297_RS23550 46868f013e1611844ada46b66031b4dd 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 40.324 T 16-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 Spa2297_RS03710 eb100f4eea18b8570010300e2de96448 359 PANTHER PTHR22893:SF7 1 355 2.7E-168 T 16-09-2016 Spa2297_RS03710 eb100f4eea18b8570010300e2de96448 359 Gene3D G3DSA:3.20.20.70 1 352 5.0E-137 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS03710 eb100f4eea18b8570010300e2de96448 359 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 344 9.1E-78 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS03710 eb100f4eea18b8570010300e2de96448 359 PANTHER PTHR22893 1 355 2.7E-168 T 16-09-2016 Spa2297_RS03710 eb100f4eea18b8570010300e2de96448 359 SUPERFAMILY SSF51395 1 358 1.65E-121 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 37 355 2.0E-70 T 16-09-2016 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 PANTHER PTHR30006 1 359 1.0E-119 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 Gene3D G3DSA:3.40.190.10 140 290 9.5E-20 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 Gene3D G3DSA:3.40.190.10 291 351 1.5E-34 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 Gene3D G3DSA:3.40.190.10 5 135 1.5E-34 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 Pfam PF13343 Bacterial extracellular solute-binding protein 86 321 3.9E-20 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 SUPERFAMILY SSF53850 38 356 1.99E-52 T 16-09-2016 Spa2297_RS23850 a39bc40084ede70e6352b1af7d37e00d 361 PANTHER PTHR30006:SF3 1 359 1.0E-119 T 16-09-2016 Spa2297_RS01120 5562563eca0a738fdb14d0894f40a684 367 PANTHER PTHR38479:SF2 1 366 2.5E-117 T 16-09-2016 Spa2297_RS01120 5562563eca0a738fdb14d0894f40a684 367 Pfam PF06224 Winged helix DNA-binding domain 31 350 3.2E-70 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS01120 5562563eca0a738fdb14d0894f40a684 367 PANTHER PTHR38479 1 366 2.5E-117 T 16-09-2016 Spa2297_RS05260 ad4e84e61cd062fc271898537fc439fc 252 PANTHER PTHR30292 1 252 1.9E-122 T 16-09-2016 Spa2297_RS05260 ad4e84e61cd062fc271898537fc439fc 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 44.146 T 16-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF Spa2297_RS05260 ad4e84e61cd062fc271898537fc439fc 252 PANTHER PTHR30292:SF0 1 252 1.9E-122 T 16-09-2016 Spa2297_RS05260 ad4e84e61cd062fc271898537fc439fc 252 SUPERFAMILY SSF88713 3 251 1.11E-93 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS05260 ad4e84e61cd062fc271898537fc439fc 252 Pfam PF03746 LamB/YcsF family 4 242 4.7E-98 T 16-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF Spa2297_RS07075 67db97116f22eee34f082325e4e3d678 430 Pfam PF06245 Protein of unknown function (DUF1015) 17 426 1.6E-113 T 16-09-2016 IPR008323 Uncharacterised conserved protein UCP033563 Spa2297_RS07075 67db97116f22eee34f082325e4e3d678 430 PANTHER PTHR36454:SF1 11 430 1.1E-154 T 16-09-2016 Spa2297_RS07075 67db97116f22eee34f082325e4e3d678 430 PANTHER PTHR36454 11 430 1.1E-154 T 16-09-2016 Spa2297_RS07075 67db97116f22eee34f082325e4e3d678 430 PIRSF PIRSF033563 14 430 1.4E-124 T 16-09-2016 IPR008323 Uncharacterised conserved protein UCP033563 Spa2297_RS09560 c43f7f63f8f33a26789e4e3f6356fb6b 114 Gene3D G3DSA:1.10.287.1080 36 83 2.9E-5 T 16-09-2016 Spa2297_RS09560 c43f7f63f8f33a26789e4e3f6356fb6b 114 SUPERFAMILY SSF101386 20 109 5.05E-11 T 16-09-2016 Spa2297_RS09560 c43f7f63f8f33a26789e4e3f6356fb6b 114 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 38 108 2.9E-5 T 16-09-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PANTHER PTHR24322:SF330 145 176 2.0E-31 T 16-09-2016 Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PANTHER PTHR24322:SF330 12 129 2.0E-31 T 16-09-2016 Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 SUPERFAMILY SSF51735 7 251 2.03E-48 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PANTHER PTHR24322 145 176 2.0E-31 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PANTHER PTHR24322 12 129 2.0E-31 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 Pfam PF00106 short chain dehydrogenase 10 186 8.1E-34 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 Gene3D G3DSA:3.40.50.720 10 216 9.6E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.0E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.0E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.0E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.0E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS06620 2df5e2e42390c239506cc7ff708efbc7 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.0E-20 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 SUPERFAMILY SSF55874 737 821 5.27E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 PANTHER PTHR21021:SF19 371 706 4.5E-73 T 16-09-2016 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 512 697 9.9E-53 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 SUPERFAMILY SSF55781 274 471 1.47E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 SUPERFAMILY SSF81606 499 697 1.23E-13 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Pfam PF13581 Histidine kinase-like ATPase domain 711 819 1.5E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Gene3D G3DSA:3.30.450.40 280 462 8.3E-28 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 SUPERFAMILY SSF55785 29 72 1.74E-7 T 16-09-2016 IPR000014 PAS domain Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Gene3D G3DSA:3.30.450.20 29 70 2.0E-7 T 16-09-2016 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 SMART SM00331 483 697 7.6E-56 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Gene3D G3DSA:3.60.40.10 624 697 5.9E-5 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 Pfam PF00989 PAS fold 32 70 9.1E-6 T 16-09-2016 IPR013767 PAS fold GO:0006355 Spa2297_RS26985 3c495bf1527adaa17d5bf6ba01c025f9 827 PANTHER PTHR21021 371 706 4.5E-73 T 16-09-2016 Spa2297_RS31750 4a547aa55e1094e7312107f6fb9c6c11 215 Gene3D G3DSA:3.40.50.10320 10 209 4.4E-37 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS31750 4a547aa55e1094e7312107f6fb9c6c11 215 SUPERFAMILY SSF102588 11 209 1.27E-32 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS31750 4a547aa55e1094e7312107f6fb9c6c11 215 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 128 3.9E-13 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 PANTHER PTHR30146 2 343 1.5E-112 T 16-09-2016 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 SUPERFAMILY SSF53822 59 339 4.71E-66 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 Gene3D G3DSA:1.10.260.40 4 47 6.5E-18 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 Pfam PF13377 Periplasmic binding protein-like domain 171 334 3.7E-35 T 16-09-2016 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 SMART SM00354 2 69 3.1E-23 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 Gene3D G3DSA:3.40.50.2300 177 315 1.4E-46 T 16-09-2016 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 PANTHER PTHR30146:SF4 2 343 1.5E-112 T 16-09-2016 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.2E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.2E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 SUPERFAMILY SSF47413 3 49 1.06E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 4.4E-14 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 Gene3D G3DSA:3.40.50.2300 51 176 4.1E-31 T 16-09-2016 Spa2297_RS09330 46c956e5a57084116c71ec2adfb71536 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS13190 a8d2e3b11fbc4a80b0d6e943fdeeab80 578 PANTHER PTHR33392 61 571 6.3E-205 T 16-09-2016 Spa2297_RS13190 a8d2e3b11fbc4a80b0d6e943fdeeab80 578 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 179 342 1.1E-36 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13190 a8d2e3b11fbc4a80b0d6e943fdeeab80 578 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 456 549 8.4E-10 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS13190 a8d2e3b11fbc4a80b0d6e943fdeeab80 578 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 179 341 1.9E-45 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13190 a8d2e3b11fbc4a80b0d6e943fdeeab80 578 PANTHER PTHR33392:SF7 61 571 6.3E-205 T 16-09-2016 Spa2297_RS06770 b4da274bf4435d03803e5a3d0bfe7c8a 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 256 9.3E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS06770 b4da274bf4435d03803e5a3d0bfe7c8a 268 Gene3D G3DSA:3.40.50.1110 32 257 5.4E-67 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS06770 b4da274bf4435d03803e5a3d0bfe7c8a 268 PANTHER PTHR37981:SF3 1 267 1.5E-133 T 16-09-2016 Spa2297_RS06770 b4da274bf4435d03803e5a3d0bfe7c8a 268 PANTHER PTHR37981 1 267 1.5E-133 T 16-09-2016 Spa2297_RS06770 b4da274bf4435d03803e5a3d0bfe7c8a 268 SUPERFAMILY SSF52266 36 256 1.48E-60 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 Gene3D G3DSA:3.10.105.10 294 494 2.1E-37 T 16-09-2016 Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 443 9.4E-70 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 PIRSF PIRSF002741 11 523 1.8E-61 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 PANTHER PTHR30290:SF7 1 528 3.5E-222 T 16-09-2016 Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 SUPERFAMILY SSF53850 33 525 6.14E-94 T 16-09-2016 Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 Gene3D G3DSA:3.40.190.10 141 293 9.6E-32 T 16-09-2016 Spa2297_RS04925 01667842d799e4cc7902dae0d3b7fe52 528 PANTHER PTHR30290 1 528 3.5E-222 T 16-09-2016 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 PANTHER PTHR22911 9 277 3.7E-118 T 16-09-2016 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 SUPERFAMILY SSF103481 35 135 1.96E-11 T 16-09-2016 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 SUPERFAMILY SSF103481 179 279 5.36E-9 T 16-09-2016 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 Pfam PF00892 EamA-like transporter family 8 130 1.7E-6 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 Pfam PF00892 EamA-like transporter family 147 278 3.4E-8 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS13765 f79665d59b70ee36a76e3c1158ee0963 281 PANTHER PTHR22911:SF61 9 277 3.7E-118 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 Gene3D G3DSA:3.40.190.10 130 190 3.0E-9 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 Gene3D G3DSA:3.40.190.10 194 221 4.9E-6 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 Gene3D G3DSA:3.40.190.10 61 86 4.9E-6 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 SUPERFAMILY SSF53850 130 216 3.62E-14 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 PANTHER PTHR30118:SF5 131 228 1.1E-18 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 PANTHER PTHR30118 131 228 1.1E-18 T 16-09-2016 Spa2297_RS28240 49644ece1dc85ee05bb52bd73380e69d 238 Pfam PF03466 LysR substrate binding domain 131 219 2.2E-6 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS16765 67487ce1f118f24b54fa5b577f5520c1 271 Gene3D G3DSA:1.10.287.110 138 175 1.5E-5 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS16765 67487ce1f118f24b54fa5b577f5520c1 271 SUPERFAMILY SSF46565 136 176 3.4E-6 T 16-09-2016 IPR001623 DnaJ domain Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 Pfam PF00375 Sodium:dicarboxylate symporter family 22 411 1.1E-100 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PANTHER PTHR11958:SF49 4 464 3.2E-270 T 16-09-2016 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 SUPERFAMILY SSF118215 22 412 6.54E-103 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 202 221 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 7.0E-26 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 Gene3D G3DSA:1.10.3860.10 16 418 7.7E-104 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS22980 fa052882fa44098b0fcb71b4c3bb0d4a 464 PANTHER PTHR11958 4 464 3.2E-270 T 16-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 Spa2297_RS14730 f7993e9694c68cecdf8f6245aa1610e6 351 Pfam PF13302 Acetyltransferase (GNAT) domain 222 331 2.7E-18 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14730 f7993e9694c68cecdf8f6245aa1610e6 351 PANTHER PTHR13256:SF10 171 335 2.9E-30 T 16-09-2016 Spa2297_RS14730 f7993e9694c68cecdf8f6245aa1610e6 351 SUPERFAMILY SSF55729 192 334 1.45E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14730 f7993e9694c68cecdf8f6245aa1610e6 351 Gene3D G3DSA:3.40.630.30 188 337 5.3E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14730 f7993e9694c68cecdf8f6245aa1610e6 351 PANTHER PTHR13256 171 335 2.9E-30 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 SUPERFAMILY SSF53474 388 514 6.76E-23 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 SUPERFAMILY SSF53474 89 147 6.76E-23 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 SUPERFAMILY SSF53474 190 244 6.76E-23 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992:SF878 190 277 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992:SF878 31 145 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992:SF878 399 516 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 Pfam PF00561 alpha/beta hydrolase fold 98 479 1.1E-29 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992 190 277 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992 31 145 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 PANTHER PTHR10992 399 516 4.2E-51 T 16-09-2016 Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 Gene3D G3DSA:3.40.50.1820 391 514 2.2E-57 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 Gene3D G3DSA:3.40.50.1820 64 146 2.2E-57 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02400 104557961d9697ca93610b6348eeaf41 536 Gene3D G3DSA:3.40.50.1820 188 312 2.2E-57 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 PANTHER PTHR11938:SF101 1 80 3.0E-21 T 16-09-2016 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 16-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 SUPERFAMILY SSF54862 1 103 1.68E-22 T 16-09-2016 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 Pfam PF00037 4Fe-4S binding domain 34 56 9.9E-10 T 16-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 Pfam PF11953 Domain of unknown function (DUF3470) 69 102 4.1E-5 T 16-09-2016 IPR022569 Ferredoxin, C-terminal Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 Gene3D G3DSA:3.30.70.20 4 76 2.7E-19 T 16-09-2016 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 PRINTS PR00354 7Fe ferredoxin signature 9 19 8.0E-11 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 PRINTS PR00354 7Fe ferredoxin signature 19 29 8.0E-11 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 PRINTS PR00354 7Fe ferredoxin signature 35 52 8.0E-11 T 16-09-2016 IPR000813 7Fe ferredoxin GO:0009055 Spa2297_RS26580 3e1153b4c51b69ad83f56eff839b80bf 116 PANTHER PTHR11938 1 80 3.0E-21 T 16-09-2016 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 PANTHER PTHR10108:SF795 80 337 5.5E-107 T 16-09-2016 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 PIRSF PIRSF003085 42 428 1.2E-113 T 16-09-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 PANTHER PTHR10108 357 425 5.5E-107 T 16-09-2016 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 PANTHER PTHR10108 80 337 5.5E-107 T 16-09-2016 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 Pfam PF02353 Mycolic acid cyclopropane synthetase 149 418 7.2E-83 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 SUPERFAMILY SSF53335 155 423 1.84E-64 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 PANTHER PTHR10108:SF795 357 425 5.5E-107 T 16-09-2016 Spa2297_RS30510 aa49d6c27883c8310f47ee668d409641 428 Gene3D G3DSA:3.40.50.150 143 423 3.3E-90 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00230 220e8b9a7ad4ab804ccb0646668630b8 165 PIRSF PIRSF005859 10 165 2.0E-41 T 16-09-2016 IPR004307 TspO/MBR-related protein GO:0016021 Spa2297_RS00230 220e8b9a7ad4ab804ccb0646668630b8 165 PANTHER PTHR10057 8 164 6.4E-35 T 16-09-2016 IPR004307 TspO/MBR-related protein GO:0016021 Spa2297_RS00230 220e8b9a7ad4ab804ccb0646668630b8 165 Pfam PF03073 TspO/MBR family 22 161 8.0E-41 T 16-09-2016 IPR004307 TspO/MBR-related protein GO:0016021 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 SUPERFAMILY SSF103473 19 216 2.88E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 SUPERFAMILY SSF103473 498 523 2.88E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 SUPERFAMILY SSF103473 268 439 2.88E-68 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 Pfam PF07690 Major Facilitator Superfamily 38 429 1.1E-49 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 PANTHER PTHR23501 23 529 4.4E-194 T 16-09-2016 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 PANTHER PTHR23501:SF48 23 529 4.4E-194 T 16-09-2016 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 33 518 2.7E-88 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 Gene3D G3DSA:1.20.1250.20 499 523 2.1E-21 T 16-09-2016 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 Gene3D G3DSA:1.20.1250.20 34 213 3.5E-27 T 16-09-2016 Spa2297_RS09985 ac0ea9a7e180a901f2bd06c9bb8be3b2 536 Gene3D G3DSA:1.20.1250.20 290 440 2.1E-21 T 16-09-2016 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 SUPERFAMILY SSF161098 9 203 1.11E-33 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 217 1.7E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 112 2.3E-16 T 16-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 PANTHER PTHR30614:SF7 9 218 7.0E-110 T 16-09-2016 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 Gene3D G3DSA:1.10.3720.10 6 217 9.0E-36 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24435 b6fdf501f9ebd8d0f122838faf24f4e4 221 PANTHER PTHR30614 9 218 7.0E-110 T 16-09-2016 Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 PANTHER PTHR24220:SF517 17 222 1.3E-86 T 16-09-2016 Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 SMART SM00382 28 205 2.8E-5 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 SUPERFAMILY SSF52540 17 213 1.09E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 Pfam PF00005 ABC transporter 20 156 9.1E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 PANTHER PTHR24220 17 222 1.3E-86 T 16-09-2016 Spa2297_RS24645 f59b865b0fc019b05a7097cba3bf3c34 692 Gene3D G3DSA:3.40.50.300 16 216 8.3E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08045 532d543ea4a4601e68a13085a7ecaf1e 259 Pfam PF01909 Nucleotidyltransferase domain 21 55 1.7E-5 T 16-09-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spa2297_RS08045 532d543ea4a4601e68a13085a7ecaf1e 259 SUPERFAMILY SSF81301 11 62 2.81E-9 T 16-09-2016 Spa2297_RS08045 532d543ea4a4601e68a13085a7ecaf1e 259 Gene3D G3DSA:3.30.460.10 14 98 7.1E-11 T 16-09-2016 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 PANTHER PTHR30193 1 258 7.1E-57 T 16-09-2016 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 TIGRFAM TIGR03226 PhnU: 2-aminoethylphosphonate ABC transporter, permease protein 2 260 6.1E-93 T 16-09-2016 IPR017636 2-aminoethylphosphonate ABC transporter system, permease protein phnU GO:0016020|GO:0033223 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 SUPERFAMILY SSF161098 2 252 1.01E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 PANTHER PTHR30193:SF20 1 258 7.1E-57 T 16-09-2016 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 Gene3D G3DSA:1.10.3720.10 2 259 8.6E-49 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12170 facc55d16d6e429be1bca16c8f7ff78a 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 63 258 5.8E-20 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 PANTHER PTHR36999 1 739 0.0 T 16-09-2016 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 Gene3D G3DSA:3.40.718.10 337 360 4.7E-32 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 Gene3D G3DSA:3.40.718.10 185 287 4.7E-32 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 Gene3D G3DSA:3.40.718.10 536 643 4.7E-32 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 16-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 PIRSF PIRSF009407 1 739 0.0 T 16-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 16-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Spa2297_RS28610 35887b799eba2af35f3ccd2c1afff0a7 739 SUPERFAMILY SSF53659 4 738 0.0 T 16-09-2016 Spa2297_RS28665 c887c2b694ec82d98ae3e34620ca6d28 291 PANTHER PTHR32243:SF8 12 291 3.0E-136 T 16-09-2016 Spa2297_RS28665 c887c2b694ec82d98ae3e34620ca6d28 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 281 8.0E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28665 c887c2b694ec82d98ae3e34620ca6d28 291 SUPERFAMILY SSF161098 17 291 1.21E-61 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28665 c887c2b694ec82d98ae3e34620ca6d28 291 Gene3D G3DSA:1.10.3720.10 15 278 1.8E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28665 c887c2b694ec82d98ae3e34620ca6d28 291 PANTHER PTHR32243 12 291 3.0E-136 T 16-09-2016 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 22 211 1.9E-28 T 16-09-2016 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 145 6.1E-10 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 176 200 6.1E-10 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 6.1E-10 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 Gene3D G3DSA:3.50.50.60 10 210 4.9E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 SUPERFAMILY SSF51905 148 192 8.29E-8 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 SUPERFAMILY SSF51905 282 387 8.29E-8 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 SUPERFAMILY SSF51905 20 219 8.85E-41 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 6.5E-6 T 16-09-2016 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 6.5E-6 T 16-09-2016 Spa2297_RS14370 e045b3dc51cc88f73e4cc8abae2aa705 399 PANTHER PTHR23023 15 388 1.3E-84 T 16-09-2016 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 Pfam PF00480 ROK family 72 308 3.2E-27 T 16-09-2016 IPR000600 ROK family Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 PANTHER PTHR18964:SF119 1 311 2.7E-155 T 16-09-2016 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 Gene3D G3DSA:3.30.420.40 154 289 2.1E-26 T 16-09-2016 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 177 188 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 Gene3D G3DSA:3.30.420.40 22 153 2.5E-19 T 16-09-2016 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 PANTHER PTHR18964 1 311 2.7E-155 T 16-09-2016 Spa2297_RS01000 9135d659845efc234486d2ce4d048255 311 SUPERFAMILY SSF53067 29 309 6.22E-28 T 16-09-2016 Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 Pfam PF07730 Histidine kinase 200 265 1.6E-15 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 344 1.8E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 PANTHER PTHR24421:SF19 54 386 1.9E-85 T 16-09-2016 Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 Gene3D G3DSA:3.30.565.10 304 385 3.1E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 SUPERFAMILY SSF55874 274 384 7.6E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14105 997d7c0033420da81e3b01e14fbb472b 386 PANTHER PTHR24421 54 386 1.9E-85 T 16-09-2016 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 18 461 5.4E-145 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 238 292 - T 16-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 Gene3D G3DSA:1.20.210.10 8 525 6.7E-190 T 16-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 9 513 5.1E-210 T 16-09-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PANTHER PTHR10422:SF6 7 525 8.5E-286 T 16-09-2016 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 82 106 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 8 33 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 186 205 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 282 297 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 125 137 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 339 357 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 367 386 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 236 257 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 325 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 417 438 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 55 78 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 215 236 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 157 175 9.4E-101 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 SUPERFAMILY SSF81442 7 516 3.14E-173 T 16-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS29985 1fae43b831d0cb1b2b4013f3bdbf2e35 538 PANTHER PTHR10422 7 525 8.5E-286 T 16-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 Spa2297_RS01200 6dd3ddb37847a49a431760282751547f 492 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 158 244 4.0E-5 T 16-09-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Spa2297_RS01200 6dd3ddb37847a49a431760282751547f 492 PIRSF PIRSF012666 1 492 8.9E-237 T 16-09-2016 IPR016602 Uncharacterised conserved protein UCP012666 Spa2297_RS01200 6dd3ddb37847a49a431760282751547f 492 SUPERFAMILY SSF55931 37 472 1.18E-60 T 16-09-2016 Spa2297_RS29815 04ac3a2b7525f59fd9eee2e6720a6b92 136 Pfam PF03259 Roadblock/LC7 domain 10 101 1.0E-15 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS29815 04ac3a2b7525f59fd9eee2e6720a6b92 136 SMART SM00960 9 101 1.2E-19 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS29815 04ac3a2b7525f59fd9eee2e6720a6b92 136 SUPERFAMILY SSF103196 3 130 6.63E-28 T 16-09-2016 Spa2297_RS29815 04ac3a2b7525f59fd9eee2e6720a6b92 136 Gene3D G3DSA:3.30.450.30 6 127 4.8E-22 T 16-09-2016 Spa2297_RS29815 04ac3a2b7525f59fd9eee2e6720a6b92 136 PANTHER PTHR36222 1 132 1.5E-25 T 16-09-2016 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 PANTHER PTHR18895 53 261 2.5E-55 T 16-09-2016 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 53 244 7.1E-40 T 16-09-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 Gene3D G3DSA:1.10.8.10 53 82 5.6E-4 T 16-09-2016 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 PANTHER PTHR18895:SF64 53 261 2.5E-55 T 16-09-2016 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 24 270 4.8E-124 T 16-09-2016 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 SUPERFAMILY SSF53335 60 238 2.59E-40 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 Pfam PF05175 Methyltransferase small domain 82 183 4.4E-10 T 16-09-2016 IPR007848 Methyltransferase small domain GO:0008168 Spa2297_RS03065 86023cff1092bb65f79797c53ca35da8 275 Gene3D G3DSA:3.40.50.150 83 259 9.7E-46 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04015 d03efc19ecf403050a3db6407b4d115b 161 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 38 146 6.1E-19 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS04015 d03efc19ecf403050a3db6407b4d115b 161 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 36 153 17.762 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS04015 d03efc19ecf403050a3db6407b4d115b 161 PANTHER PTHR28259 39 161 1.7E-30 T 16-09-2016 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 PANTHER PTHR10889 60 311 3.9E-129 T 16-09-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 Gene3D G3DSA:3.20.20.70 53 311 1.0E-93 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 SUPERFAMILY SSF51569 60 299 1.05E-72 T 16-09-2016 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 PANTHER PTHR10889:SF3 60 311 3.9E-129 T 16-09-2016 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 Pfam PF01791 DeoC/LacD family aldolase 56 298 3.2E-26 T 16-09-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 SMART SM01133 59 300 1.1E-73 T 16-09-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Spa2297_RS20800 5c4614cb6f5b809e110dfface459bec5 319 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 62 281 3.0E-53 T 16-09-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 Spa2297_RS14100 4220fdb8cc5e2b05c82a164f2a5a7ea2 220 PANTHER PTHR30353 1 219 1.7E-74 T 16-09-2016 IPR032818 DedA family Spa2297_RS14100 4220fdb8cc5e2b05c82a164f2a5a7ea2 220 PANTHER PTHR30353:SF13 1 219 1.7E-74 T 16-09-2016 Spa2297_RS14100 4220fdb8cc5e2b05c82a164f2a5a7ea2 220 Pfam PF09335 SNARE associated Golgi protein 45 172 1.6E-21 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 SUPERFAMILY SSF53092 3 148 8.2E-19 T 16-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 PANTHER PTHR10804:SF86 69 374 9.0E-86 T 16-09-2016 Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 Gene3D G3DSA:3.90.230.10 150 375 4.5E-69 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 PANTHER PTHR10804 69 374 9.0E-86 T 16-09-2016 Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 Pfam PF00557 Metallopeptidase family M24 158 359 5.1E-57 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 SUPERFAMILY SSF55920 149 375 4.19E-73 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 Gene3D G3DSA:3.40.350.10 3 144 5.9E-15 T 16-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Spa2297_RS25625 c436fb45906ede39525f4f4888bc7614 376 Pfam PF01321 Creatinase/Prolidase N-terminal domain 18 150 1.2E-15 T 16-09-2016 IPR000587 Creatinase, N-terminal GO:0016787 Spa2297_RS22450 14ab5f455ab42d35b741790361552423 111 Gene3D G3DSA:3.30.70.1090 1 107 1.8E-45 T 16-09-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 Spa2297_RS22450 14ab5f455ab42d35b741790361552423 111 Pfam PF04673 Polyketide synthesis cyclase 2 106 2.0E-44 T 16-09-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 Spa2297_RS22450 14ab5f455ab42d35b741790361552423 111 SUPERFAMILY SSF54909 1 107 6.97E-41 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS22450 14ab5f455ab42d35b741790361552423 111 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 106 2.0E-55 T 16-09-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 Spa2297_RS03075 d83118b3df6575c8db1d52d366056134 201 PANTHER PTHR19372 7 201 4.3E-70 T 16-09-2016 Spa2297_RS03075 d83118b3df6575c8db1d52d366056134 201 Gene3D G3DSA:3.90.420.10 29 198 4.9E-47 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS03075 d83118b3df6575c8db1d52d366056134 201 Pfam PF00174 Oxidoreductase molybdopterin binding domain 37 181 1.5E-30 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS03075 d83118b3df6575c8db1d52d366056134 201 SUPERFAMILY SSF56524 18 200 1.57E-56 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 Gene3D G3DSA:1.10.1660.10 10 64 4.0E-21 T 16-09-2016 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 Gene3D G3DSA:1.10.1660.10 65 128 2.0E-6 T 16-09-2016 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 PANTHER PTHR30204 1 117 2.9E-21 T 16-09-2016 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 Pfam PF13411 MerR HTH family regulatory protein 11 77 1.6E-16 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 SMART SM00422 11 78 1.1E-20 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 SUPERFAMILY SSF46955 11 117 1.68E-21 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 1.2E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 1.2E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS30800 165f4c8bf3e581fb89382aaef6184e5d 361 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 1.2E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 PANTHER PTHR26402 5 218 4.7E-90 T 16-09-2016 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 1.2E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 Gene3D G3DSA:1.10.10.10 158 222 1.4E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 SUPERFAMILY SSF52172 4 176 6.4E-16 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 SUPERFAMILY SSF46894 142 205 4.42E-16 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 204 5.2E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 Gene3D G3DSA:3.40.50.2300 4 157 4.0E-23 T 16-09-2016 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 PANTHER PTHR26402:SF582 5 218 4.7E-90 T 16-09-2016 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 SMART SM00421 157 219 3.2E-15 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 Pfam PF00072 Response regulator receiver domain 7 117 1.9E-13 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS19430 90e52407279f5cd711cf147c719a8d2f 223 SMART SM00448 5 129 1.6E-9 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS23395 65950888569540af527da4f403df7407 571 Gene3D G3DSA:3.20.20.140 494 570 4.0E-141 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 Gene3D G3DSA:3.20.20.140 155 435 4.0E-141 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 Pfam PF01979 Amidohydrolase family 137 456 2.6E-43 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS23395 65950888569540af527da4f403df7407 571 SUPERFAMILY SSF51338 428 474 3.42E-41 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS23395 65950888569540af527da4f403df7407 571 SUPERFAMILY SSF51338 15 141 3.42E-41 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 5.0E-23 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 304 321 5.0E-23 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 343 359 5.0E-23 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 5.0E-23 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PANTHER PTHR22642:SF7 329 507 2.4E-203 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PANTHER PTHR22642:SF7 39 305 2.4E-203 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PANTHER PTHR22642 329 507 2.4E-203 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 PANTHER PTHR22642 39 305 2.4E-203 T 16-09-2016 Spa2297_RS23395 65950888569540af527da4f403df7407 571 Pfam PF00449 Urease alpha-subunit, N-terminal domain 15 131 3.2E-37 T 16-09-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 ProSitePatterns PS01120 Urease nickel ligands signature. 139 152 - T 16-09-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 Hamap MF_01953 Urease subunit alpha [ureC]. 13 571 46.254 T 16-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 Spa2297_RS23395 65950888569540af527da4f403df7407 571 SUPERFAMILY SSF51556 487 571 1.14E-139 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS23395 65950888569540af527da4f403df7407 571 SUPERFAMILY SSF51556 141 438 1.14E-139 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS23395 65950888569540af527da4f403df7407 571 Gene3D G3DSA:2.30.40.10 14 154 6.6E-43 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 Pfam PF00589 Phage integrase family 192 380 7.8E-21 T 16-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 83 134 4.7E-5 T 16-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 PANTHER PTHR22683:SF41 47 388 1.0E-61 T 16-09-2016 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 SUPERFAMILY SSF56349 82 387 1.09E-54 T 16-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 PANTHER PTHR22683 47 388 1.0E-61 T 16-09-2016 Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 Gene3D G3DSA:1.10.150.130 83 174 1.9E-14 T 16-09-2016 IPR023109 Integrase/recombinase, N-terminal Spa2297_RS07650 7787b75167046ea0f297ba03dfd16b22 426 Gene3D G3DSA:1.10.443.10 186 393 1.8E-37 T 16-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 PANTHER PTHR11908:SF97 162 326 1.0E-145 T 16-09-2016 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 SUPERFAMILY SSF55447 225 324 4.06E-25 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 3.7E-53 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 PANTHER PTHR11908:SF97 1 119 1.0E-145 T 16-09-2016 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 319 3.4E-16 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Gene3D G3DSA:3.30.390.50 225 324 3.6E-31 T 16-09-2016 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 PANTHER PTHR11908 1 119 1.0E-145 T 16-09-2016 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 SMART SM01092 226 324 2.5E-24 T 16-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 SUPERFAMILY SSF56176 2 219 8.18E-61 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Gene3D G3DSA:3.30.43.10 2 51 2.6E-19 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Gene3D G3DSA:3.30.465.10 58 113 8.5E-34 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 Gene3D G3DSA:3.30.465.10 157 219 8.5E-34 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS30245 35a40c57254a05228759edb17134d83a 330 PANTHER PTHR11908 162 326 1.0E-145 T 16-09-2016 Spa2297_RS04780 bd76abc296f67b9c224d7c8d4cca3f7d 180 PANTHER PTHR20935 11 93 4.1E-15 T 16-09-2016 Spa2297_RS04780 bd76abc296f67b9c224d7c8d4cca3f7d 180 Gene3D G3DSA:3.40.50.1240 10 176 2.4E-53 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS04780 bd76abc296f67b9c224d7c8d4cca3f7d 180 SMART SM00855 12 124 5.2E-5 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS04780 bd76abc296f67b9c224d7c8d4cca3f7d 180 SUPERFAMILY SSF53254 11 165 1.01E-26 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS04780 bd76abc296f67b9c224d7c8d4cca3f7d 180 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 13 141 9.5E-10 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS08010 fb05f08927fffbc64c08eaa43f77fc44 219 Gene3D G3DSA:3.30.565.10 53 163 5.7E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08010 fb05f08927fffbc64c08eaa43f77fc44 219 SUPERFAMILY SSF55874 66 162 1.05E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08010 fb05f08927fffbc64c08eaa43f77fc44 219 Pfam PF13581 Histidine kinase-like ATPase domain 44 145 3.7E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01350 4cb73897a90fc8f773b29a8d7c00b7e3 487 Gene3D G3DSA:3.40.50.1820 299 385 3.5E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01350 4cb73897a90fc8f773b29a8d7c00b7e3 487 Gene3D G3DSA:3.40.50.1820 69 194 3.5E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01350 4cb73897a90fc8f773b29a8d7c00b7e3 487 SUPERFAMILY SSF53474 327 381 1.65E-14 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01350 4cb73897a90fc8f773b29a8d7c00b7e3 487 SUPERFAMILY SSF53474 44 196 1.65E-14 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26550 d2a88957c70fc2a33d280444851fc9cc 298 Pfam PF12697 Alpha/beta hydrolase family 76 263 1.9E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26550 d2a88957c70fc2a33d280444851fc9cc 298 Gene3D G3DSA:3.40.50.1820 63 280 1.0E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26550 d2a88957c70fc2a33d280444851fc9cc 298 SUPERFAMILY SSF53474 51 280 2.41E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 SMART SM00116 225 273 3.2 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 SMART SM00116 285 333 1.3 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 PANTHER PTHR22777:SF7 4 334 8.4E-153 T 16-09-2016 Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 Gene3D G3DSA:3.10.580.10 221 331 6.6E-12 T 16-09-2016 Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 SUPERFAMILY SSF54631 205 334 9.85E-21 T 16-09-2016 Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 Pfam PF00571 CBS domain 285 333 0.0011 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 Pfam PF01595 Domain of unknown function DUF21 10 197 7.7E-38 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS17115 a387ad05df93bc5019e7d1df0cf8157f 340 PANTHER PTHR22777 4 334 8.4E-153 T 16-09-2016 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 Gene3D G3DSA:1.10.1740.10 4 92 3.1E-12 T 16-09-2016 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 SUPERFAMILY SSF88659 93 149 4.58E-8 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 Pfam PF04542 Sigma-70 region 2 5 69 4.9E-10 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 PANTHER PTHR30173:SF15 3 347 5.0E-147 T 16-09-2016 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 SUPERFAMILY SSF88946 3 85 1.18E-12 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 Gene3D G3DSA:1.10.10.10 93 149 2.5E-11 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 Pfam PF08281 Sigma-70, region 4 98 148 7.9E-8 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS14195 ce3db7f75d23bc3a67d20fac3483501e 395 PANTHER PTHR30173 3 347 5.0E-147 T 16-09-2016 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 PANTHER PTHR11785:SF342 157 468 6.2E-160 T 16-09-2016 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 PANTHER PTHR11785:SF342 1 139 6.2E-160 T 16-09-2016 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 PIRSF PIRSF006060 17 467 4.8E-88 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 PANTHER PTHR11785 157 468 6.2E-160 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 PANTHER PTHR11785 1 139 6.2E-160 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS28955 0deb816d9c5d34ed3a9428d5616cbd18 468 Pfam PF13520 Amino acid permease 32 438 5.4E-56 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 PANTHER PTHR33406 19 751 6.2E-163 T 16-09-2016 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 Gene3D G3DSA:1.20.1640.10 527 730 5.4E-29 T 16-09-2016 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 Gene3D G3DSA:1.20.1640.10 166 359 2.4E-30 T 16-09-2016 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 PANTHER PTHR33406:SF5 19 751 6.2E-163 T 16-09-2016 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 Pfam PF03176 MMPL family 62 390 2.9E-56 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 Pfam PF03176 MMPL family 430 727 4.0E-37 T 16-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 SUPERFAMILY SSF82866 490 724 2.22E-26 T 16-09-2016 Spa2297_RS30115 c08eebfb33fb0ad63c9f0aa591f91e01 754 SUPERFAMILY SSF82866 136 354 6.02E-30 T 16-09-2016 Spa2297_RS25455 92ea665dda406b3d7926d4729f58484a 285 SUPERFAMILY SSF88713 65 279 2.22E-43 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS25455 92ea665dda406b3d7926d4729f58484a 285 Gene3D G3DSA:3.20.20.370 66 280 1.7E-45 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS25455 92ea665dda406b3d7926d4729f58484a 285 Pfam PF01522 Polysaccharide deacetylase 69 209 1.8E-27 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS25455 92ea665dda406b3d7926d4729f58484a 285 PANTHER PTHR10587 99 282 1.2E-23 T 16-09-2016 Spa2297_RS29210 f0026519f9083b75b6d2ab41413424a7 139 Pfam PF13581 Histidine kinase-like ATPase domain 20 136 5.8E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29210 f0026519f9083b75b6d2ab41413424a7 139 SUPERFAMILY SSF55874 28 134 4.45E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29210 f0026519f9083b75b6d2ab41413424a7 139 Gene3D G3DSA:3.30.565.10 12 135 1.7E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572 455 497 1.4E-127 T 16-09-2016 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 Pfam PF02687 FtsX-like permease family 336 477 7.7E-16 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572 184 419 1.4E-127 T 16-09-2016 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572 8 120 1.4E-127 T 16-09-2016 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572:SF7 8 120 1.4E-127 T 16-09-2016 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572:SF7 455 497 1.4E-127 T 16-09-2016 Spa2297_RS20900 ec6e27a491933c7216dcc0d7f5a5e994 498 PANTHER PTHR30572:SF7 184 419 1.4E-127 T 16-09-2016 Spa2297_RS16350 c136c5eb6f65adc3c5659c4fcf158acd 70 ProDom PD267558 MEMBRANE TRANSMEMBRANE SPANNING SCO3924 1 70 3.0E-18 T 16-09-2016 IPR020246 Uncharacterised protein family SCO3924 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 SUPERFAMILY SSF53383 12 420 2.56E-105 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 Gene3D G3DSA:3.90.1150.10 325 421 3.3E-30 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 Gene3D G3DSA:3.90.1150.10 21 61 3.3E-30 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 420 3.8E-202 T 16-09-2016 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|UniPathway: UPA00067 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 Pfam PF00202 Aminotransferase class-III 27 418 1.2E-75 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 Gene3D G3DSA:3.40.640.10 64 318 2.6E-62 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 PANTHER PTHR11986:SF61 3 422 3.8E-267 T 16-09-2016 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 422 9.7E-136 T 16-09-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|UniPathway: UPA00067 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 PANTHER PTHR11986 3 422 3.8E-267 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS07440 7f9330323dcdd960c5b87bdb16ec866c 423 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS20940 3260341978e37cd35f54082a2879ecb8 464 Gene3D G3DSA:1.25.10.10 378 438 2.0E-5 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS20940 3260341978e37cd35f54082a2879ecb8 464 Gene3D G3DSA:1.25.10.10 7 178 9.2E-14 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS20940 3260341978e37cd35f54082a2879ecb8 464 SUPERFAMILY SSF48371 214 261 1.79E-7 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS20940 3260341978e37cd35f54082a2879ecb8 464 SUPERFAMILY SSF48371 103 183 1.79E-7 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS20940 3260341978e37cd35f54082a2879ecb8 464 SUPERFAMILY SSF48371 380 437 4.67E-5 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 8.7E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 8.7E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 8.7E-14 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 4.1E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 Pfam PF00072 Response regulator receiver domain 12 123 1.9E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 Gene3D G3DSA:1.10.10.10 131 223 4.0E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 Gene3D G3DSA:3.40.50.2300 7 130 1.3E-37 T 16-09-2016 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 PANTHER PTHR26402 10 222 2.7E-120 T 16-09-2016 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 SUPERFAMILY SSF46894 148 223 1.12E-22 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 SUPERFAMILY SSF52172 10 142 9.39E-35 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 PANTHER PTHR26402:SF564 10 222 2.7E-120 T 16-09-2016 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 SMART SM00448 10 123 6.3E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS24685 489a4aac4400d7a0ba5374918e3fa9cf 227 SMART SM00421 159 216 3.1E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS31045 0386572d05d2b8385783bdbb76f0b13b 244 PANTHER PTHR23200 31 221 3.4E-25 T 16-09-2016 Spa2297_RS31045 0386572d05d2b8385783bdbb76f0b13b 244 SUPERFAMILY SSF56281 6 230 5.01E-30 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS31045 0386572d05d2b8385783bdbb76f0b13b 244 Pfam PF00753 Metallo-beta-lactamase superfamily 30 224 6.2E-23 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS31045 0386572d05d2b8385783bdbb76f0b13b 244 Gene3D G3DSA:3.60.15.10 26 225 7.3E-30 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS31045 0386572d05d2b8385783bdbb76f0b13b 244 SMART SM00849 31 224 3.6E-17 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PANTHER PTHR22855:SF42 3 456 1.2E-206 T 16-09-2016 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 Pfam PF01039 Carboxyl transferase domain 286 413 1.3E-8 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 Pfam PF01039 Carboxyl transferase domain 48 198 8.2E-15 T 16-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PANTHER PTHR22855 3 456 1.2E-206 T 16-09-2016 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 146 163 2.1E-13 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 127 2.1E-13 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 75 89 2.1E-13 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 175 186 2.1E-13 T 16-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 Gene3D G3DSA:3.90.226.10 4 222 1.6E-33 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 SUPERFAMILY SSF52096 4 221 6.87E-43 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 Gene3D G3DSA:3.90.226.10 243 435 7.7E-29 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS10325 11dc1219f4163d07e1cfb94ed43a7c2b 456 SUPERFAMILY SSF52096 241 436 4.76E-43 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 366 3.1E-98 T 16-09-2016 IPR017741 FAD-dependent oxidoreductase, HpnW Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 PANTHER PTHR13847 1 255 3.7E-29 T 16-09-2016 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 PANTHER PTHR13847 276 369 3.7E-29 T 16-09-2016 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 Gene3D G3DSA:3.50.50.60 277 288 7.5E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 Gene3D G3DSA:3.50.50.60 130 212 7.5E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 Gene3D G3DSA:3.50.50.60 344 371 7.5E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 Gene3D G3DSA:3.50.50.60 2 70 7.5E-29 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 SUPERFAMILY SSF51905 2 213 3.75E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 SUPERFAMILY SSF51905 332 372 3.75E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS12185 ed30e4d369ff87cce25da196989f0d34 374 Pfam PF01266 FAD dependent oxidoreductase 3 370 2.2E-46 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 PANTHER PTHR33154:SF2 11 116 7.5E-52 T 16-09-2016 Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 SUPERFAMILY SSF46785 12 104 4.49E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 Gene3D G3DSA:1.10.10.10 22 104 6.4E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 SMART SM00418 25 104 6.1E-8 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 7.3E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 7.3E-7 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 Pfam PF12840 Helix-turn-helix domain 26 80 1.3E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03705 bb0da0fb6ebc5f361b51965267ae35f7 120 PANTHER PTHR33154 11 116 7.5E-52 T 16-09-2016 Spa2297_RS01315 3b73aa09d0160960e4364dafdc38866a 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 282 2.9E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01315 3b73aa09d0160960e4364dafdc38866a 294 PANTHER PTHR32243:SF18 8 294 5.2E-121 T 16-09-2016 Spa2297_RS01315 3b73aa09d0160960e4364dafdc38866a 294 SUPERFAMILY SSF161098 15 293 4.21E-63 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01315 3b73aa09d0160960e4364dafdc38866a 294 PANTHER PTHR32243 8 294 5.2E-121 T 16-09-2016 Spa2297_RS01315 3b73aa09d0160960e4364dafdc38866a 294 Gene3D G3DSA:1.10.3720.10 13 280 5.9E-61 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS09090 3c4ae41be3ad7b17720dc11218eab777 155 Pfam PF06271 RDD family 43 148 3.6E-12 T 16-09-2016 IPR010432 RDD Spa2297_RS09090 3c4ae41be3ad7b17720dc11218eab777 155 PIRSF PIRSF021697 3 155 1.2E-58 T 16-09-2016 IPR016795 Uncharacterised conserved protein UCP021697, membrane Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 SMART SM00642 36 432 5.6E-127 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 PANTHER PTHR10357 474 560 1.8E-175 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 PANTHER PTHR10357 25 441 1.8E-175 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 Gene3D G3DSA:3.90.400.10 128 205 2.2E-28 T 16-09-2016 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 Pfam PF00128 Alpha amylase, catalytic domain 51 409 1.4E-78 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 SUPERFAMILY SSF51445 26 495 1.72E-128 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 PANTHER PTHR10357:SF11 474 560 1.8E-175 T 16-09-2016 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 PANTHER PTHR10357:SF11 25 441 1.8E-175 T 16-09-2016 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 Gene3D G3DSA:3.20.20.80 206 496 1.5E-109 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 Gene3D G3DSA:3.20.20.80 26 127 1.5E-109 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS09310 94bfcc29f24114e9a022fab8697a00c9 564 Pfam PF11941 Domain of unknown function (DUF3459) 481 561 1.5E-8 T 16-09-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) Spa2297_RS28695 7e1534600a34258a6bb86f3267602aa0 298 SUPERFAMILY SSF56219 82 297 7.59E-21 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS28695 7e1534600a34258a6bb86f3267602aa0 298 Gene3D G3DSA:3.60.10.10 86 242 3.7E-6 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS28695 7e1534600a34258a6bb86f3267602aa0 298 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 88 288 1.0E-12 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS11450 5d3e7f2b306b5da4a424cc59829517d1 478 PANTHER PTHR30576:SF0 9 478 2.4E-151 T 16-09-2016 Spa2297_RS11450 5d3e7f2b306b5da4a424cc59829517d1 478 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 99 477 1.3E-96 T 16-09-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Spa2297_RS11450 5d3e7f2b306b5da4a424cc59829517d1 478 Pfam PF13727 CoA-binding domain 95 235 3.9E-8 T 16-09-2016 Spa2297_RS11450 5d3e7f2b306b5da4a424cc59829517d1 478 PANTHER PTHR30576 9 478 2.4E-151 T 16-09-2016 Spa2297_RS11450 5d3e7f2b306b5da4a424cc59829517d1 478 Pfam PF02397 Bacterial sugar transferase 292 473 5.6E-47 T 16-09-2016 IPR003362 Bacterial sugar transferase Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 Pfam PF00005 ABC transporter 21 168 4.9E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 SUPERFAMILY SSF52540 7 232 2.27E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 PANTHER PTHR24220 267 329 5.4E-206 T 16-09-2016 Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 PANTHER PTHR24220 6 246 5.4E-206 T 16-09-2016 Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 SMART SM00382 29 225 8.2E-14 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 Gene3D G3DSA:3.40.50.300 5 232 1.3E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 PANTHER PTHR24220:SF537 267 329 5.4E-206 T 16-09-2016 IPR030296 Probable ABC transporter ATP-binding protein Mkl Spa2297_RS10210 1f7de25e7255170d6f382d56318798cf 336 PANTHER PTHR24220:SF537 6 246 5.4E-206 T 16-09-2016 IPR030296 Probable ABC transporter ATP-binding protein Mkl Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 SUPERFAMILY SSF53383 34 456 1.43E-127 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 57 387 4.1E-70 T 16-09-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 Gene3D G3DSA:3.40.640.10 85 332 5.0E-26 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 38 454 8.1E-188 T 16-09-2016 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 PANTHER PTHR11999 44 458 2.6E-190 T 16-09-2016 Spa2297_RS18130 50facd1dc669f94835f2188568676e8f 473 PANTHER PTHR11999:SF111 44 458 2.6E-190 T 16-09-2016 Spa2297_RS01530 9ddc8ec34f70cf89210cf67919bed355 145 SUPERFAMILY SSF55874 53 132 1.96E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01530 9ddc8ec34f70cf89210cf67919bed355 145 Pfam PF13581 Histidine kinase-like ATPase domain 29 114 5.7E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01530 9ddc8ec34f70cf89210cf67919bed355 145 Gene3D G3DSA:3.30.565.10 54 99 1.8E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 327 8.2E-7 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 SUPERFAMILY SSF46894 264 337 9.86E-13 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 Gene3D G3DSA:1.10.10.10 264 335 1.9E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 277 291 7.3E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 307 319 7.3E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 307 7.3E-6 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17515 3d97a3590cab14d462e13a8eb82eefbb 341 SMART SM00421 274 331 3.9E-11 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 Gene3D G3DSA:3.30.360.10 190 300 6.4E-48 T 16-09-2016 Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 Gene3D G3DSA:3.40.50.720 301 354 1.4E-114 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 Gene3D G3DSA:3.40.50.720 1 189 1.4E-114 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 SUPERFAMILY SSF51735 3 185 3.15E-91 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 SUPERFAMILY SSF51735 297 356 3.15E-91 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 5.1E-32 T 16-09-2016 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 SUPERFAMILY SSF55347 190 299 1.44E-34 T 16-09-2016 Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 1.2E-220 T 16-09-2016 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 PIRSF PIRSF015578 1 360 6.5E-93 T 16-09-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS16475 f112ecd87bb2e97f36d1abd3b1cea1d1 360 PANTHER PTHR11510 4 357 2.7E-146 T 16-09-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 Pfam PF02515 CoA-transferase family III 10 375 1.4E-108 T 16-09-2016 IPR003673 CoA-transferase family III GO:0003824 Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 PANTHER PTHR24023 61 385 1.2E-136 T 16-09-2016 Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 SUPERFAMILY SSF89796 7 398 5.36E-121 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 PANTHER PTHR24023:SF593 61 385 1.2E-136 T 16-09-2016 Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 Gene3D G3DSA:3.30.1540.10 242 307 2.2E-7 T 16-09-2016 Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 Gene3D G3DSA:3.40.50.10540 308 400 4.3E-108 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS32045 0b75d01fe12eb60276c269080e086e30 403 Gene3D G3DSA:3.40.50.10540 7 222 4.3E-108 T 16-09-2016 IPR023606 CoA-transferase family III domain Spa2297_RS07945 12bf8c4a9893ccbf60a3dcbd8840a99c 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 56 108 1.6E-13 T 16-09-2016 IPR005330 MHYT domain Spa2297_RS07945 12bf8c4a9893ccbf60a3dcbd8840a99c 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 171 8.9E-15 T 16-09-2016 IPR005330 MHYT domain Spa2297_RS07945 12bf8c4a9893ccbf60a3dcbd8840a99c 292 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 231 2.3E-6 T 16-09-2016 IPR005330 MHYT domain Spa2297_RS07945 12bf8c4a9893ccbf60a3dcbd8840a99c 292 PANTHER PTHR35152 1 279 1.5E-64 T 16-09-2016 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 SUPERFAMILY SSF56003 165 745 8.5E-157 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 SMART SM01008 23 139 5.2E-38 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 450 614 5.0E-31 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 166 688 4.3E-126 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.90.1170.50 9 127 5.4E-34 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 128 179 2.7E-15 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 287 351 2.7E-15 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 139 2.1E-26 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 PANTHER PTHR11908 575 745 2.7E-244 T 16-09-2016 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 615 744 4.0E-51 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 360 449 4.0E-51 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 PANTHER PTHR11908 10 547 2.7E-244 T 16-09-2016 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 Gene3D G3DSA:3.30.365.10 180 284 1.4E-36 T 16-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 SUPERFAMILY SSF54665 9 147 1.2E-36 T 16-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 PANTHER PTHR11908:SF71 575 745 2.7E-244 T 16-09-2016 Spa2297_RS29265 d02c5b136631a93f4295cda0196a546f 745 PANTHER PTHR11908:SF71 10 547 2.7E-244 T 16-09-2016 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 Gene3D G3DSA:1.10.260.40 4 80 6.3E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 Pfam PF13560 Helix-turn-helix domain 5 84 4.5E-15 T 16-09-2016 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 PANTHER PTHR35010 1 282 8.4E-158 T 16-09-2016 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 PANTHER PTHR35010:SF1 1 282 8.4E-158 T 16-09-2016 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 SUPERFAMILY SSF47413 29 79 1.79E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS31495 874dbc9c3e3381ad22debb119f61317b 282 SMART SM00530 9 81 1.3E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS00930 ce1bdb6b6abfef10d56c75e51c618a57 271 Gene3D G3DSA:3.40.50.150 3 271 3.2E-112 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00930 ce1bdb6b6abfef10d56c75e51c618a57 271 PIRSF PIRSF017393 2 271 1.0E-105 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS00930 ce1bdb6b6abfef10d56c75e51c618a57 271 SUPERFAMILY SSF53335 16 264 2.21E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00930 ce1bdb6b6abfef10d56c75e51c618a57 271 Pfam PF04672 S-adenosyl methyltransferase 6 271 7.1E-119 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 SUPERFAMILY SSF53223 1 121 5.85E-37 T 16-09-2016 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.6E-35 T 16-09-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.0E-63 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 Gene3D G3DSA:3.40.50.720 139 264 3.3E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 Gene3D G3DSA:3.40.192.10 7 138 4.9E-45 T 16-09-2016 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 SUPERFAMILY SSF51735 122 281 2.56E-40 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 36.56 T 16-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 5.2E-62 T 16-09-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 Spa2297_RS20345 5eafec566185c6d58ea0f1b446e3b733 284 PANTHER PTHR10025 1 284 3.2E-140 T 16-09-2016 Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 Gene3D G3DSA:3.40.50.1000 184 278 7.7E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 Gene3D G3DSA:3.40.50.1000 19 90 7.7E-51 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 22 275 9.3E-45 T 16-09-2016 IPR000150 Cof protein GO:0016787 Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 186 248 2.8E-11 T 16-09-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 SUPERFAMILY SSF56784 19 278 1.8E-58 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 PANTHER PTHR10000:SF8 19 278 3.8E-74 T 16-09-2016 Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 Pfam PF08282 haloacid dehalogenase-like hydrolase 23 275 1.3E-44 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS16220 9c1cd1522c01be30d2c1cc32d8753a0a 280 PANTHER PTHR10000 19 278 3.8E-74 T 16-09-2016 Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 SUPERFAMILY SSF52922 188 319 9.82E-39 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 SMART SM00861 1 176 6.2E-71 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 Gene3D G3DSA:3.40.50.920 193 315 1.5E-43 T 16-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 Pfam PF02779 Transketolase, pyrimidine binding domain 2 174 4.0E-46 T 16-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 PANTHER PTHR11624:SF79 1 321 4.4E-206 T 16-09-2016 Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 Gene3D G3DSA:3.40.50.970 1 189 8.1E-76 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 SUPERFAMILY SSF52518 2 179 8.83E-68 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 Pfam PF02780 Transketolase, C-terminal domain 191 311 1.5E-38 T 16-09-2016 IPR033248 Transketolase, C-terminal domain Spa2297_RS16890 4dfcd5b61aeab74c701c13bd9cc52d5f 321 PANTHER PTHR11624 1 321 4.4E-206 T 16-09-2016 IPR033247 Transketolase family Spa2297_RS11475 77b754c9d406ed480921c97660f9202a 209 Pfam PF02706 Chain length determinant protein 21 125 7.7E-6 T 16-09-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PRINTS PR00133 Glycosyl hydrolase family 3 signature 242 258 1.1E-7 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PRINTS PR00133 Glycosyl hydrolase family 3 signature 138 154 1.1E-7 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PRINTS PR00133 Glycosyl hydrolase family 3 signature 164 183 1.1E-7 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PRINTS PR00133 Glycosyl hydrolase family 3 signature 319 337 1.1E-7 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 Gene3D G3DSA:3.20.20.300 95 423 1.2E-113 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 Gene3D G3DSA:3.40.50.1700 424 612 1.3E-18 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 437 599 5.4E-16 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 SUPERFAMILY SSF51445 40 434 2.84E-107 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 319 336 - T 16-09-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PANTHER PTHR30480:SF5 44 74 8.7E-252 T 16-09-2016 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PANTHER PTHR30480:SF5 90 614 8.7E-252 T 16-09-2016 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PANTHER PTHR30480 90 614 8.7E-252 T 16-09-2016 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 PANTHER PTHR30480 44 74 8.7E-252 T 16-09-2016 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 58 398 6.2E-119 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS11670 dfe6bf0c3cc38a9f60dabe412e91d242 615 SUPERFAMILY SSF52279 437 613 3.92E-17 T 16-09-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 SUPERFAMILY SSF47413 17 62 2.34E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 Gene3D G3DSA:1.10.260.40 18 62 6.3E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 Pfam PF13560 Helix-turn-helix domain 18 72 1.8E-9 T 16-09-2016 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 PANTHER PTHR10245:SF7 18 271 2.2E-26 T 16-09-2016 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 PANTHER PTHR10245 18 271 2.2E-26 T 16-09-2016 Spa2297_RS17735 3fa06fc96830b40d0eddfd8b2cff876e 271 SMART SM00530 20 75 1.3E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS05120 067e2c9219af04ddefd80c2bc5fa1060 149 PANTHER PTHR30175 6 99 4.1E-31 T 16-09-2016 Spa2297_RS05120 067e2c9219af04ddefd80c2bc5fa1060 149 SUPERFAMILY SSF51261 3 147 2.96E-37 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS05120 067e2c9219af04ddefd80c2bc5fa1060 149 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 122 7.2E-29 T 16-09-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- Spa2297_RS05120 067e2c9219af04ddefd80c2bc5fa1060 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 1.4E-38 T 16-09-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- Spa2297_RS05120 067e2c9219af04ddefd80c2bc5fa1060 149 Gene3D G3DSA:2.70.70.10 3 148 2.4E-46 T 16-09-2016 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 SUPERFAMILY SSF52161 4 144 1.44E-60 T 16-09-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 2.0E-61 T 16-09-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 PIRSF PIRSF002181 2 147 1.7E-48 T 16-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 Pfam PF00572 Ribosomal protein L13 14 138 9.7E-58 T 16-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.467 T 16-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 16-09-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 PANTHER PTHR11545 2 144 2.1E-75 T 16-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19955 5e490106b378d759221b84e6cb385279 147 Gene3D G3DSA:3.90.1180.10 3 141 3.1E-64 T 16-09-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 Spa2297_RS03785 c2622e2dbbc349f8ebce7a93207a9618 356 SUPERFAMILY SSF53756 82 339 1.33E-17 T 16-09-2016 Spa2297_RS03785 c2622e2dbbc349f8ebce7a93207a9618 356 PANTHER PTHR21015 1 335 2.6E-85 T 16-09-2016 Spa2297_RS03785 c2622e2dbbc349f8ebce7a93207a9618 356 Gene3D G3DSA:3.40.50.2000 163 321 8.7E-9 T 16-09-2016 Spa2297_RS03785 c2622e2dbbc349f8ebce7a93207a9618 356 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 5 154 2.7E-26 T 16-09-2016 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 Spa2297_RS03785 c2622e2dbbc349f8ebce7a93207a9618 356 PANTHER PTHR21015:SF21 1 335 2.6E-85 T 16-09-2016 Spa2297_RS09225 6efe6d8a85d7d5554d7e7c050bca9283 239 ProDom PD068376 ORF2 SECRETED GLNII PRECURSOR SIGNAL 1 239 4.0E-59 T 16-09-2016 Spa2297_RS12300 24def1fe5b30a1172d1b8cf5b20bc9bd 143 Pfam PF03259 Roadblock/LC7 domain 10 98 2.8E-21 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS12300 24def1fe5b30a1172d1b8cf5b20bc9bd 143 SMART SM00960 10 100 1.2E-17 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS12300 24def1fe5b30a1172d1b8cf5b20bc9bd 143 PANTHER PTHR36222 1 140 3.2E-46 T 16-09-2016 Spa2297_RS12300 24def1fe5b30a1172d1b8cf5b20bc9bd 143 SUPERFAMILY SSF103196 3 130 1.38E-25 T 16-09-2016 Spa2297_RS12300 24def1fe5b30a1172d1b8cf5b20bc9bd 143 Gene3D G3DSA:3.30.450.30 5 127 8.5E-16 T 16-09-2016 Spa2297_RS15010 8778c4fea588046a57930f9f5b4acc45 140 PANTHER PTHR38009:SF1 1 140 9.8E-44 T 16-09-2016 Spa2297_RS15010 8778c4fea588046a57930f9f5b4acc45 140 Pfam PF06841 T4-like virus tail tube protein gp19 9 139 7.4E-30 T 16-09-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 Spa2297_RS15010 8778c4fea588046a57930f9f5b4acc45 140 PANTHER PTHR38009 1 140 9.8E-44 T 16-09-2016 Spa2297_RS15010 8778c4fea588046a57930f9f5b4acc45 140 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 139 8.4E-25 T 16-09-2016 IPR011747 Conserved hypothetical protein CHP02241 Spa2297_RS11140 ea9b7981ac6bc228c30e74d4568c8f14 460 Pfam PF00324 Amino acid permease 26 434 3.1E-104 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS11140 ea9b7981ac6bc228c30e74d4568c8f14 460 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 16-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 Spa2297_RS11140 ea9b7981ac6bc228c30e74d4568c8f14 460 PANTHER PTHR11785 15 460 8.4E-284 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS11140 ea9b7981ac6bc228c30e74d4568c8f14 460 PANTHER PTHR11785:SF386 15 460 8.4E-284 T 16-09-2016 Spa2297_RS11140 ea9b7981ac6bc228c30e74d4568c8f14 460 PIRSF PIRSF006060 2 456 8.9E-68 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-17 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.0E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.0E-5 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 PANTHER PTHR30146:SF59 1 350 4.7E-212 T 16-09-2016 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 Gene3D G3DSA:3.40.50.2300 182 314 4.5E-45 T 16-09-2016 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 SMART SM00354 1 71 2.9E-29 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 PANTHER PTHR30146 1 350 4.7E-212 T 16-09-2016 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 Gene3D G3DSA:3.40.50.2300 58 181 3.7E-53 T 16-09-2016 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 SUPERFAMILY SSF53822 60 337 3.53E-74 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 Gene3D G3DSA:1.10.260.40 2 57 1.5E-24 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 SUPERFAMILY SSF47413 1 59 1.53E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS07890 906197ae8ecb280b77a5c1bea3f2b0cb 366 Pfam PF13377 Periplasmic binding protein-like domain 174 335 5.7E-39 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 16 596 4.1E-128 T 16-09-2016 IPR019986 DAK2 domain-containing protein YloV Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434:SF4 90 255 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 SMART SM01121 290 596 1.6E-100 T 16-09-2016 IPR033470 Uncharacterised protein, DhaK domain Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434 3 61 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 Pfam PF02734 DAK2 domain 94 231 3.1E-22 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 SMART SM01120 39 232 1.6E-45 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 SUPERFAMILY SSF101473 10 62 6.15E-26 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 SUPERFAMILY SSF101473 91 233 6.15E-26 T 16-09-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434 280 596 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434 90 255 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434:SF4 280 596 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 PANTHER PTHR33434:SF4 3 61 4.9E-186 T 16-09-2016 Spa2297_RS23610 6475cc6a3e27897bffd36e1ed40a53f3 596 Pfam PF13684 Dihydroxyacetone kinase family 291 596 1.2E-78 T 16-09-2016 IPR033470 Uncharacterised protein, DhaK domain Spa2297_RS08075 7ed1f4aade1cfcffc4220a3d682488ca 139 Pfam PF13564 DoxX-like family 22 117 1.3E-16 T 16-09-2016 IPR032808 DoxX family Spa2297_RS30400 5b20e743e639bc48dd45d0d8a95415f9 122 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 23 37 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS30400 5b20e743e639bc48dd45d0d8a95415f9 122 PANTHER PTHR35344:SF1 8 121 4.8E-43 T 16-09-2016 Spa2297_RS30400 5b20e743e639bc48dd45d0d8a95415f9 122 PANTHER PTHR35344 8 121 4.8E-43 T 16-09-2016 Spa2297_RS30400 5b20e743e639bc48dd45d0d8a95415f9 122 Pfam PF00741 Gas vesicle protein 22 60 4.2E-17 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 PANTHER PTHR30328 10 193 9.4E-31 T 16-09-2016 Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 SUPERFAMILY SSF46689 11 73 1.8E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 58 8.5E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 PANTHER PTHR30328:SF6 10 193 9.4E-31 T 16-09-2016 Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 SUPERFAMILY SSF48498 91 196 3.12E-9 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS14350 20f467b469fde296707b1da842a311f5 211 Gene3D G3DSA:1.10.357.10 7 187 1.0E-23 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS17800 f97209524a1b2da506f8ac1201f9977e 195 Pfam PF01928 CYTH domain 3 137 1.5E-10 T 16-09-2016 IPR023577 CYTH domain Spa2297_RS17800 f97209524a1b2da506f8ac1201f9977e 195 SUPERFAMILY SSF55154 4 137 4.25E-17 T 16-09-2016 IPR033469 CYTH-like domain Spa2297_RS17800 f97209524a1b2da506f8ac1201f9977e 195 Gene3D G3DSA:2.40.320.10 4 140 4.5E-23 T 16-09-2016 IPR023577 CYTH domain Spa2297_RS17800 f97209524a1b2da506f8ac1201f9977e 195 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 51 133 2.0E-6 T 16-09-2016 Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 SUPERFAMILY SSF161111 2 206 7.45E-36 T 16-09-2016 Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 Gene3D G3DSA:3.30.70.1350 207 282 6.9E-6 T 16-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 PANTHER PTHR13414 1 266 5.7E-95 T 16-09-2016 Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 Gene3D G3DSA:1.20.1510.10 2 204 2.3E-32 T 16-09-2016 IPR027469 Cation efflux protein transmembrane domain Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 Pfam PF01545 Cation efflux family 2 204 1.4E-34 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS29855 59b09021615b7d02fa6c03657328da5e 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 2 287 1.6E-64 T 16-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Pfam PF00384 Molybdopterin oxidoreductase 120 494 2.5E-28 T 16-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 PANTHER PTHR11615 280 759 6.2E-294 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 PANTHER PTHR11615:SF114 280 759 6.2E-294 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 PANTHER PTHR11615:SF114 1 263 6.2E-294 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 SUPERFAMILY SSF53706 58 631 7.46E-145 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 755 2.1E-289 T 16-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Gene3D G3DSA:3.40.50.740 120 193 2.1E-55 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Gene3D G3DSA:3.40.50.740 395 628 2.1E-55 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Gene3D G3DSA:3.40.228.10 194 394 5.7E-54 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 PANTHER PTHR11615 1 263 6.2E-294 T 16-09-2016 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Pfam PF01568 Molydopterin dinucleotide binding domain 642 749 2.8E-10 T 16-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 PIRSF PIRSF000144 5 759 0.0 T 16-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 SUPERFAMILY SSF50692 632 756 4.75E-18 T 16-09-2016 IPR009010 Aspartate decarboxylase-like domain Spa2297_RS08140 f919d9baedcd6b07d499e1f8b9b285a9 759 Gene3D G3DSA:2.40.40.20 631 755 2.2E-12 T 16-09-2016 Spa2297_RS27820 71e82c75cd261d5528023d925c1d2564 191 Gene3D G3DSA:3.40.630.30 7 169 2.8E-35 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS27820 71e82c75cd261d5528023d925c1d2564 191 Pfam PF13302 Acetyltransferase (GNAT) domain 18 155 3.8E-20 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS27820 71e82c75cd261d5528023d925c1d2564 191 PANTHER PTHR13256 14 163 6.3E-36 T 16-09-2016 Spa2297_RS27820 71e82c75cd261d5528023d925c1d2564 191 SUPERFAMILY SSF55729 10 163 1.54E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS27820 71e82c75cd261d5528023d925c1d2564 191 PANTHER PTHR13256:SF21 14 163 6.3E-36 T 16-09-2016 Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 PANTHER PTHR23091:SF276 3 179 3.1E-47 T 16-09-2016 Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 Gene3D G3DSA:3.40.630.30 29 177 5.2E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 Pfam PF00583 Acetyltransferase (GNAT) family 77 152 3.8E-15 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 PANTHER PTHR23091 3 179 3.1E-47 T 16-09-2016 Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 PIRSF PIRSF037663 28 180 1.5E-11 T 16-09-2016 IPR017255 Acetyltransferase, GNAT, predicted Spa2297_RS10635 6e2231d899945bc2bcfc00ff2a5fb98c 180 SUPERFAMILY SSF55729 22 155 2.19E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 SUPERFAMILY SSF53244 344 503 1.2E-45 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 15 501 33.204 T 16-09-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Pfam PF02875 Mur ligase family, glutamate ligase domain 344 428 1.9E-19 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 PANTHER PTHR23135 22 503 6.8E-190 T 16-09-2016 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Gene3D G3DSA:3.40.1190.10 116 347 1.3E-77 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Pfam PF08245 Mur ligase middle domain 123 323 1.4E-51 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 SUPERFAMILY SSF63418 16 114 2.62E-21 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 35 501 6.7E-144 T 16-09-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Gene3D G3DSA:3.40.1390.10 31 113 2.1E-20 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Gene3D G3DSA:3.90.190.20 348 495 3.0E-50 T 16-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 SUPERFAMILY SSF53623 114 343 4.84E-66 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 PANTHER PTHR23135:SF4 22 503 6.8E-190 T 16-09-2016 Spa2297_RS08550 f81951c903a7e8bd107554c57f9cdac0 506 Pfam PF01225 Mur ligase family, catalytic domain 35 109 1.8E-13 T 16-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 SUPERFAMILY SSF52242 208 266 2.2E-6 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 Gene3D G3DSA:1.10.1660.10 22 91 5.9E-12 T 16-09-2016 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 Gene3D G3DSA:3.40.50.280 210 265 1.7E-4 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 Pfam PF02607 B12 binding domain 127 197 9.1E-9 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 Pfam PF13411 MerR HTH family regulatory protein 22 86 1.1E-11 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 SMART SM00422 21 90 3.3E-6 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 PANTHER PTHR30204 13 98 3.7E-21 T 16-09-2016 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 PANTHER PTHR30204:SF17 13 98 3.7E-21 T 16-09-2016 Spa2297_RS00795 8f35ace059bdec390b515a47e5f08587 331 SUPERFAMILY SSF46955 21 87 6.41E-12 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 PANTHER PTHR11019 6 277 3.4E-83 T 16-09-2016 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 SUPERFAMILY SSF46689 224 273 3.58E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 Pfam PF02311 AraC-like ligand binding domain 17 146 1.1E-23 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 Gene3D G3DSA:1.10.10.60 173 224 6.8E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 Gene3D G3DSA:1.10.10.60 225 272 4.6E-9 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 SUPERFAMILY SSF46689 174 221 1.21E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 Gene3D G3DSA:2.60.120.280 30 152 6.3E-11 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 Pfam PF12833 Helix-turn-helix domain 193 270 2.0E-20 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 SMART SM00342 187 269 2.0E-25 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 SUPERFAMILY SSF51215 30 152 6.67E-20 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS24370 e8ad70b2be8c106ae56422c4e232866d 288 PANTHER PTHR11019:SF75 6 277 3.4E-83 T 16-09-2016 Spa2297_RS04225 d3fa15c4b5aa7302bbd49f95e00aa7ba 419 Pfam PF01590 GAF domain 106 213 1.5E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS21130 3f7606faae75d574b2fc5d99b0925b2f 492 Pfam PF02447 GntP family permease 31 490 9.0E-130 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS21130 3f7606faae75d574b2fc5d99b0925b2f 492 PIRSF PIRSF002746 25 492 3.6E-167 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS21130 3f7606faae75d574b2fc5d99b0925b2f 492 PANTHER PTHR30354 25 492 4.1E-271 T 16-09-2016 Spa2297_RS21130 3f7606faae75d574b2fc5d99b0925b2f 492 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 31 492 1.0E-117 T 16-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spa2297_RS21130 3f7606faae75d574b2fc5d99b0925b2f 492 PANTHER PTHR30354:SF2 25 492 4.1E-271 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 SUPERFAMILY SSF54980 415 510 1.58E-23 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Gene3D G3DSA:2.40.30.10 211 304 9.1E-19 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 SMART SM00838 414 498 0.0012 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Pfam PF00009 Elongation factor Tu GTP binding domain 19 198 6.7E-51 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Pfam PF03144 Elongation factor Tu domain 2 222 292 3.3E-7 T 16-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Pfam PF00679 Elongation factor G C-terminus 415 495 2.2E-21 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Gene3D G3DSA:3.30.70.240 417 505 4.7E-21 T 16-09-2016 IPR000640 Translation elongation factor EFG, V domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PANTHER PTHR23115 2 612 6.5E-269 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PANTHER PTHR23115:SF97 2 612 6.5E-269 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Pfam PF06421 GTP-binding protein LepA C-terminus 505 610 2.8E-48 T 16-09-2016 IPR013842 GTP-binding protein LepA, C-terminal Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Hamap MF_00071 Elongation factor 4 [lepA]. 1 614 281.388 T 16-09-2016 IPR006297 Elongation factor 4 GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 SUPERFAMILY SSF54980 308 387 2.7E-19 T 16-09-2016 IPR009022 Elongation factor G, III-V domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 193 3.2E-19 T 16-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 SUPERFAMILY SSF50447 182 296 1.51E-24 T 16-09-2016 IPR009000 Translation protein, beta-barrel domain Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Gene3D G3DSA:3.40.50.300 15 210 5.0E-57 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 16-09-2016 IPR031157 Tr-type G domain, conserved site Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 Gene3D G3DSA:3.30.70.870 308 385 7.8E-25 T 16-09-2016 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 SUPERFAMILY SSF52540 14 218 9.93E-55 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PRINTS PR00315 GTP-binding elongation factor signature 107 118 4.1E-13 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PRINTS PR00315 GTP-binding elongation factor signature 91 101 4.1E-13 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.1E-13 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PRINTS PR00315 GTP-binding elongation factor signature 143 152 4.1E-13 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.1E-13 T 16-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spa2297_RS10790 68929c04e8e256b5e54fa10f283425c3 622 TIGRFAM TIGR01393 lepA: elongation factor 4 19 612 3.7E-290 T 16-09-2016 IPR006297 Elongation factor 4 GO:0005525 Spa2297_RS31815 5b39c3608c0b6f31fb68e15826ae7b48 492 Pfam PF02397 Bacterial sugar transferase 299 486 3.1E-54 T 16-09-2016 IPR003362 Bacterial sugar transferase Spa2297_RS31815 5b39c3608c0b6f31fb68e15826ae7b48 492 Pfam PF13727 CoA-binding domain 103 228 3.1E-7 T 16-09-2016 Spa2297_RS31815 5b39c3608c0b6f31fb68e15826ae7b48 492 PANTHER PTHR30576:SF4 8 492 1.2E-213 T 16-09-2016 Spa2297_RS31815 5b39c3608c0b6f31fb68e15826ae7b48 492 PANTHER PTHR30576 8 492 1.2E-213 T 16-09-2016 Spa2297_RS31815 5b39c3608c0b6f31fb68e15826ae7b48 492 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 40 492 5.8E-119 T 16-09-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 SUPERFAMILY SSF53155 11 92 1.08E-11 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 147 153 - T 16-09-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 PANTHER PTHR10815:SF5 5 178 6.1E-54 T 16-09-2016 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 11 91 1.6E-4 T 16-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 98 176 9.3E-28 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 98 178 1.5E-28 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 SUPERFAMILY SSF46767 97 178 1.83E-26 T 16-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 PANTHER PTHR10815 5 178 6.1E-54 T 16-09-2016 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 Gene3D G3DSA:1.10.10.10 97 178 1.3E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 Gene3D G3DSA:3.30.160.70 7 91 6.5E-7 T 16-09-2016 Spa2297_RS07955 0ec6b769bc7ffcd7f57a899325908621 184 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 179 37.817 T 16-09-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 Spa2297_RS17165 1f7fc75299b2acce3724878a7bdecce1 206 PANTHER PTHR33393:SF4 23 201 2.2E-47 T 16-09-2016 Spa2297_RS17165 1f7fc75299b2acce3724878a7bdecce1 206 PANTHER PTHR33393 23 201 2.2E-47 T 16-09-2016 Spa2297_RS17165 1f7fc75299b2acce3724878a7bdecce1 206 SUPERFAMILY SSF63817 50 199 2.35E-15 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS17165 1f7fc75299b2acce3724878a7bdecce1 206 Pfam PF04203 Sortase family 59 198 3.8E-18 T 16-09-2016 IPR005754 Sortase family Spa2297_RS17165 1f7fc75299b2acce3724878a7bdecce1 206 Gene3D G3DSA:2.40.260.10 59 189 4.4E-7 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 208 222 - T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 Gene3D G3DSA:3.40.640.10 24 265 6.9E-62 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 Gene3D G3DSA:3.90.1150.10 266 389 1.7E-32 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 PANTHER PTHR11808:SF44 22 392 5.6E-235 T 16-09-2016 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 PANTHER PTHR11808 22 392 5.6E-235 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 SUPERFAMILY SSF53383 54 389 6.83E-82 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 PIRSF PIRSF001434 15 391 5.9E-107 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS16370 6801e82d11371544d85d3b25496f1ccb 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 53 387 9.5E-82 T 16-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 Pfam PF16868 NMT1-like family 46 327 3.1E-44 T 16-09-2016 IPR011852 TRAP transporter solute receptor, TAXI family Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 SUPERFAMILY SSF53850 42 327 1.87E-53 T 16-09-2016 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 PANTHER PTHR30024 3 327 1.9E-67 T 16-09-2016 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 Gene3D G3DSA:3.40.190.10 263 327 7.5E-27 T 16-09-2016 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 Gene3D G3DSA:3.40.190.10 42 121 7.5E-27 T 16-09-2016 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 PANTHER PTHR30024:SF5 3 327 1.9E-67 T 16-09-2016 Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 13 329 2.5E-73 T 16-09-2016 IPR011852 TRAP transporter solute receptor, TAXI family Spa2297_RS24460 af4ce4f3c8b8af6cdd7620749d2c0e4d 331 Gene3D G3DSA:3.40.190.10 125 262 1.0E-25 T 16-09-2016 Spa2297_RS25975 8d555468e0e149d6e2e2f4c18a59a72d 251 PANTHER PTHR21631 2 229 8.1E-68 T 16-09-2016 Spa2297_RS25975 8d555468e0e149d6e2e2f4c18a59a72d 251 SUPERFAMILY SSF51621 2 241 3.35E-49 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS25975 8d555468e0e149d6e2e2f4c18a59a72d 251 Gene3D G3DSA:3.20.20.60 2 210 6.0E-49 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS25975 8d555468e0e149d6e2e2f4c18a59a72d 251 PANTHER PTHR21631:SF18 2 229 8.1E-68 T 16-09-2016 Spa2297_RS25975 8d555468e0e149d6e2e2f4c18a59a72d 251 Pfam PF13714 Phosphoenolpyruvate phosphomutase 4 229 1.0E-65 T 16-09-2016 Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 Gene3D G3DSA:2.30.110.10 14 146 4.2E-28 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 PANTHER PTHR35176 1 140 2.3E-40 T 16-09-2016 Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 98 1.1E-13 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 1.7E-39 T 16-09-2016 IPR019920 F420-binding domain, putative Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 PANTHER PTHR35176:SF3 1 140 2.3E-40 T 16-09-2016 Spa2297_RS16025 42aa2c468cdb1d46392e9e36f11b8a76 156 SUPERFAMILY SSF50475 14 140 5.43E-30 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 Pfam PF05977 Transmembrane secretion effector 37 429 2.5E-34 T 16-09-2016 IPR010290 Transmembrane secretion effector Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 PANTHER PTHR23513:SF9 24 435 2.3E-145 T 16-09-2016 Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 SUPERFAMILY SSF103473 34 432 7.32E-35 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 PANTHER PTHR23513 24 435 2.3E-145 T 16-09-2016 Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 Gene3D G3DSA:1.20.1250.20 40 226 1.5E-17 T 16-09-2016 Spa2297_RS02135 094e50e48a93537336ed84bfce044bbb 436 Gene3D G3DSA:1.20.1250.20 252 429 3.1E-7 T 16-09-2016 Spa2297_RS03750 dc03bebe8b2efa16586e5df2909e3f87 496 Pfam PF13515 Fusaric acid resistance protein-like 198 323 1.9E-13 T 16-09-2016 Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 Hamap MF_00973 Gluconeogenesis factor. 44 355 32.889 T 16-09-2016 IPR010119 Gluconeogenesis factor Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 Gene3D G3DSA:3.40.50.10680 121 354 6.1E-44 T 16-09-2016 Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 Pfam PF01933 Uncharacterised protein family UPF0052 48 313 6.5E-71 T 16-09-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 SUPERFAMILY SSF142338 45 349 3.53E-84 T 16-09-2016 Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 PANTHER PTHR30135 1 363 4.0E-133 T 16-09-2016 Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 48 352 7.8E-83 T 16-09-2016 IPR010119 Gluconeogenesis factor Spa2297_RS07865 889a0362b0ef08bb84734e1e05e809ff 363 PANTHER PTHR30135:SF3 1 363 4.0E-133 T 16-09-2016 Spa2297_RS30780 cc7bf9ea480832f78cb6f6603e8295ce 148 Pfam PF01475 Ferric uptake regulator family 16 130 1.4E-16 T 16-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spa2297_RS30780 cc7bf9ea480832f78cb6f6603e8295ce 148 Gene3D G3DSA:1.10.10.10 11 84 1.4E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30780 cc7bf9ea480832f78cb6f6603e8295ce 148 PANTHER PTHR33202 1 140 4.8E-34 T 16-09-2016 Spa2297_RS30780 cc7bf9ea480832f78cb6f6603e8295ce 148 SUPERFAMILY SSF46785 11 138 5.13E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS30780 cc7bf9ea480832f78cb6f6603e8295ce 148 PANTHER PTHR33202:SF7 1 140 4.8E-34 T 16-09-2016 Spa2297_RS19770 a05d1afa7c83647e594ad968a9909c0b 321 Pfam PF14433 SUKH-3 immunity protein 180 312 1.8E-25 T 16-09-2016 IPR025850 SUKH-3 immunity protein Spa2297_RS19770 a05d1afa7c83647e594ad968a9909c0b 321 Pfam PF14433 SUKH-3 immunity protein 6 139 3.8E-19 T 16-09-2016 IPR025850 SUKH-3 immunity protein Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 Pfam PF00156 Phosphoribosyl transferase domain 56 162 1.7E-12 T 16-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 PANTHER PTHR19278 1 180 7.9E-51 T 16-09-2016 Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 Gene3D G3DSA:3.40.50.2020 6 179 7.4E-50 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 172 7.0E-37 T 16-09-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 SUPERFAMILY SSF53271 4 179 1.97E-37 T 16-09-2016 IPR029057 Phosphoribosyltransferase-like Spa2297_RS17570 6d25b0af6b46014d91de88447f17c085 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 25.033 T 16-09-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS04835 6b35003af59fa44e011f71f692391f0f 207 Pfam PF09335 SNARE associated Golgi protein 32 160 5.0E-20 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS04835 6b35003af59fa44e011f71f692391f0f 207 PANTHER PTHR30353:SF2 2 201 1.8E-93 T 16-09-2016 Spa2297_RS04835 6b35003af59fa44e011f71f692391f0f 207 PANTHER PTHR30353 2 201 1.8E-93 T 16-09-2016 IPR032818 DedA family Spa2297_RS19735 541b1074d9de236a1aa83c7a88a4b693 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 3.2E-20 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 SUPERFAMILY SSF64288 61 234 1.07E-23 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 Pfam PF07702 UTRA domain 97 232 1.2E-18 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 Gene3D G3DSA:1.10.10.10 11 77 1.1E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 SMART SM00866 95 237 8.7E-10 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 Gene3D G3DSA:3.40.1410.10 97 235 1.9E-23 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 PANTHER PTHR11751:SF432 206 228 3.0E-12 T 16-09-2016 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 PANTHER PTHR11751:SF432 1 76 3.0E-12 T 16-09-2016 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 PANTHER PTHR11751 206 228 3.0E-12 T 16-09-2016 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 PANTHER PTHR11751 1 76 3.0E-12 T 16-09-2016 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 SUPERFAMILY SSF46785 3 87 2.72E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 SMART SM00345 14 73 4.7E-10 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS09205 d785076165701cbdd1afbec8921108ff 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 7.6E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 SUPERFAMILY SSF53901 282 403 7.32E-46 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Gene3D G3DSA:3.40.47.10 288 403 1.1E-60 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Gene3D G3DSA:3.40.47.10 144 186 1.1E-60 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 SUPERFAMILY SSF53901 3 277 1.13E-63 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Gene3D G3DSA:3.40.47.10 187 287 1.3E-55 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Gene3D G3DSA:3.40.47.10 5 128 1.3E-55 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 PANTHER PTHR18919 2 230 1.2E-259 T 16-09-2016 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 PANTHER PTHR18919:SF12 2 230 1.2E-259 T 16-09-2016 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 16-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 3.6E-48 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 PANTHER PTHR18919:SF12 252 404 1.2E-259 T 16-09-2016 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 2.9E-138 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 PANTHER PTHR18919 252 404 1.2E-259 T 16-09-2016 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 Pfam PF00108 Thiolase, N-terminal domain 7 230 1.4E-44 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS28030 9cd317c79ca6dbf04afe23c65f63aefb 404 PIRSF PIRSF000429 1 404 2.1E-112 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS19170 0e9260a3bab4031be6be796182c9c2c0 126 Pfam PF03793 PASTA domain 10 71 1.4E-7 T 16-09-2016 IPR005543 PASTA domain Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 SUPERFAMILY SSF75217 115 267 1.57E-38 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 Gene3D G3DSA:3.30.1330.30 7 103 3.5E-16 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 PANTHER PTHR12029:SF52 1 266 8.4E-146 T 16-09-2016 Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 PANTHER PTHR12029 1 266 8.4E-146 T 16-09-2016 Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 Pfam PF00588 SpoU rRNA Methylase family 121 263 3.5E-33 T 16-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 SUPERFAMILY SSF55315 6 105 8.95E-17 T 16-09-2016 IPR029064 50S ribosomal protein L30e-like Spa2297_RS05940 b046acf030f7673f5fe9c713229889d6 272 Gene3D G3DSA:3.40.1280.10 116 266 1.2E-50 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 SUPERFAMILY SSF100939 2 253 1.9E-44 T 16-09-2016 IPR016194 SPOC-like, C-terminal domain Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 252 30.087 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 SMART SM00559 52 181 8.8E-43 T 16-09-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 PANTHER PTHR41251 1 297 5.9E-107 T 16-09-2016 Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 PIRSF PIRSF006493 1 347 3.8E-72 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 PANTHER PTHR41251:SF1 1 297 5.9E-107 T 16-09-2016 Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 178 9.0E-32 T 16-09-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 254 5.8E-90 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS22430 ccced278e389d20a47590037374f4a7d 347 Gene3D G3DSA:2.40.290.10 4 147 5.2E-10 T 16-09-2016 IPR016194 SPOC-like, C-terminal domain Spa2297_RS04010 06d898808b8341c6f0cd2ff878bae040 117 Pfam PF02641 Uncharacterized ACR, COG1993 12 105 1.4E-35 T 16-09-2016 IPR003793 Domain of unknown function DUF190 Spa2297_RS04010 06d898808b8341c6f0cd2ff878bae040 117 Gene3D G3DSA:3.30.70.120 2 116 4.8E-41 T 16-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spa2297_RS04010 06d898808b8341c6f0cd2ff878bae040 117 PANTHER PTHR35983 3 114 1.6E-40 T 16-09-2016 Spa2297_RS04010 06d898808b8341c6f0cd2ff878bae040 117 SUPERFAMILY SSF54913 9 106 9.34E-31 T 16-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spa2297_RS18205 1f02631c5f819dcd55a9e33f8884fc06 177 Pfam PF13474 SnoaL-like domain 11 153 2.0E-28 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS18205 1f02631c5f819dcd55a9e33f8884fc06 177 PANTHER PTHR34957 50 161 4.9E-59 T 16-09-2016 Spa2297_RS18205 1f02631c5f819dcd55a9e33f8884fc06 177 PANTHER PTHR34957 2 34 4.9E-59 T 16-09-2016 Spa2297_RS18205 1f02631c5f819dcd55a9e33f8884fc06 177 Gene3D G3DSA:3.10.450.50 6 162 5.4E-57 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS18205 1f02631c5f819dcd55a9e33f8884fc06 177 SUPERFAMILY SSF54427 7 153 4.7E-41 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS22250 7bc37757fd8da58dedc93f03b0d046d3 262 PANTHER PTHR10108:SF847 20 185 1.6E-42 T 16-09-2016 Spa2297_RS22250 7bc37757fd8da58dedc93f03b0d046d3 262 SUPERFAMILY SSF53335 22 227 1.96E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22250 7bc37757fd8da58dedc93f03b0d046d3 262 Gene3D G3DSA:3.40.50.150 19 260 2.3E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22250 7bc37757fd8da58dedc93f03b0d046d3 262 Pfam PF13649 Methyltransferase domain 58 157 6.4E-16 T 16-09-2016 Spa2297_RS22250 7bc37757fd8da58dedc93f03b0d046d3 262 PANTHER PTHR10108 20 185 1.6E-42 T 16-09-2016 Spa2297_RS05065 c76536d6b4fe6bce1878cf66c13b71de 157 PANTHER PTHR15160 1 152 1.4E-36 T 16-09-2016 Spa2297_RS05065 c76536d6b4fe6bce1878cf66c13b71de 157 SUPERFAMILY SSF103256 3 136 8.5E-47 T 16-09-2016 IPR003729 Bifunctional nuclease domain GO:0004518 Spa2297_RS05065 c76536d6b4fe6bce1878cf66c13b71de 157 Pfam PF02577 Bifunctional nuclease 6 128 8.9E-46 T 16-09-2016 IPR003729 Bifunctional nuclease domain GO:0004518 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 SUPERFAMILY SSF56194 209 348 5.75E-34 T 16-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Gene3D G3DSA:3.30.465.10 223 239 5.5E-48 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Gene3D G3DSA:3.30.465.10 76 188 5.5E-48 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 343 2.5E-47 T 16-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Gene3D G3DSA:3.30.43.10 8 72 5.9E-23 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 PANTHER PTHR21071:SF6 1 351 4.1E-150 T 16-09-2016 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Gene3D G3DSA:3.90.78.10 240 350 4.7E-45 T 16-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 SUPERFAMILY SSF56176 8 185 1.5E-36 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 76.849 T 16-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 213 347 1.0E-37 T 16-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 PANTHER PTHR21071 1 351 4.1E-150 T 16-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS19585 b8bf56f9ee409240cb5e5a780172a411 351 Pfam PF01565 FAD binding domain 23 141 1.8E-21 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 PANTHER PTHR32243:SF40 33 164 4.6E-103 T 16-09-2016 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 PANTHER PTHR32243 33 164 4.6E-103 T 16-09-2016 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 Gene3D G3DSA:1.10.3720.10 35 316 3.7E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 PANTHER PTHR32243 180 326 4.6E-103 T 16-09-2016 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 316 3.5E-14 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 SUPERFAMILY SSF161098 83 312 3.01E-53 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30950 948cf44921f0e2199ccdb9d8d43d1877 327 PANTHER PTHR32243:SF40 180 326 4.6E-103 T 16-09-2016 Spa2297_RS10200 960e70f6763e84cc4779ea83cc042c94 268 Pfam PF02405 Permease MlaE 52 255 1.2E-59 T 16-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 Spa2297_RS10200 960e70f6763e84cc4779ea83cc042c94 268 PANTHER PTHR30188:SF1 4 268 1.0E-150 T 16-09-2016 Spa2297_RS10200 960e70f6763e84cc4779ea83cc042c94 268 PANTHER PTHR30188 4 268 1.0E-150 T 16-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 PANTHER PTHR10909 1 413 7.7E-188 T 16-09-2016 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 PANTHER PTHR10909:SF207 1 413 7.7E-188 T 16-09-2016 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 Gene3D G3DSA:1.20.140.10 231 393 6.0E-22 T 16-09-2016 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 SUPERFAMILY SSF56645 16 238 3.27E-25 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 Gene3D G3DSA:2.40.110.10 135 230 5.3E-11 T 16-09-2016 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 391 3.5E-18 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS31605 c66a5dd008dc2d754463630eb40f91ff 569 SUPERFAMILY SSF47203 243 398 5.15E-26 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 SUPERFAMILY SSF53098 8 149 2.53E-39 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 Gene3D G3DSA:3.30.420.10 7 150 7.2E-44 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 PANTHER PTHR10642:SF0 3 165 5.0E-40 T 16-09-2016 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 Hamap MF_00042 Ribonuclease H [rnhA]. 6 158 35.334 T 16-09-2016 IPR022892 Ribonuclease H GO:0004523 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 Pfam PF00075 RNase H 8 149 3.2E-28 T 16-09-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 Spa2297_RS02265 52734420c997b666a28151dbdaee4031 235 PANTHER PTHR10642 3 165 5.0E-40 T 16-09-2016 Spa2297_RS20820 b65889ae4c3fc8d9e00caf749df7af7d 145 Pfam PF13772 AIG2-like family 59 140 8.5E-22 T 16-09-2016 Spa2297_RS20820 b65889ae4c3fc8d9e00caf749df7af7d 145 PANTHER PTHR12935 1 145 1.2E-43 T 16-09-2016 IPR017939 Gamma-glutamylcyclotransferase GO:0003839|GO:0006750 KEGG: 00480+2.3.2.4|MetaCyc: PWY-4041 Spa2297_RS20820 b65889ae4c3fc8d9e00caf749df7af7d 145 Gene3D G3DSA:3.10.490.10 1 145 3.4E-46 T 16-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like Spa2297_RS20820 b65889ae4c3fc8d9e00caf749df7af7d 145 SUPERFAMILY SSF110857 1 119 9.68E-14 T 16-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Pfam PF12705 PD-(D/E)XK nuclease superfamily 996 1142 2.3E-9 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:3.40.50.300 651 686 1.7E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:3.40.50.300 725 775 1.7E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:3.40.50.300 338 450 1.7E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 320 3.0E-43 T 16-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 SUPERFAMILY SSF52540 17 486 4.29E-109 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 SUPERFAMILY SSF52540 729 775 4.29E-109 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 SUPERFAMILY SSF52540 541 685 4.29E-109 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:1.10.486.10 451 629 9.8E-23 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:3.40.50.300 19 153 2.0E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Gene3D G3DSA:3.40.50.300 206 325 2.0E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070 629 691 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070 946 1147 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070 7 569 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070 869 909 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070 728 826 0.0 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Pfam PF13361 UvrD-like helicase C-terminal domain 336 487 6.7E-12 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 Pfam PF13361 UvrD-like helicase C-terminal domain 556 747 1.2E-13 T 16-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 SUPERFAMILY SSF52980 997 1133 5.09E-6 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070:SF5 629 691 0.0 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070:SF5 946 1147 0.0 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070:SF5 7 569 0.0 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070:SF5 869 909 0.0 T 16-09-2016 Spa2297_RS21890 59f5e7c90226ff46c3be4700d18104f2 1179 PANTHER PTHR11070:SF5 728 826 0.0 T 16-09-2016 Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 SUPERFAMILY SSF53383 18 402 1.86E-109 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 Pfam PF00155 Aminotransferase class I and II 69 398 1.5E-32 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 Gene3D G3DSA:3.40.640.10 69 286 1.5E-81 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 Gene3D G3DSA:3.90.1150.10 287 401 2.0E-10 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 PANTHER PTHR11751:SF386 25 406 6.6E-173 T 16-09-2016 Spa2297_RS18625 b83174508e9d33127258d9d90f506802 407 PANTHER PTHR11751 25 406 6.6E-173 T 16-09-2016 Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Gene3D G3DSA:3.40.50.1220 4 22 1.2E-40 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Gene3D G3DSA:3.40.50.1220 74 113 1.2E-40 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Gene3D G3DSA:3.40.50.1220 168 239 1.2E-40 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Gene3D G3DSA:3.30.1600.10 23 62 4.6E-21 T 16-09-2016 IPR026591 Sirtuin family, catalytic core small domain Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Gene3D G3DSA:3.30.1600.10 114 161 4.6E-21 T 16-09-2016 IPR026591 Sirtuin family, catalytic core small domain Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 PANTHER PTHR11085 7 241 3.6E-84 T 16-09-2016 IPR003000 Sirtuin family GO:0070403 Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 Pfam PF02146 Sir2 family 12 192 5.3E-44 T 16-09-2016 IPR003000 Sirtuin family GO:0070403 Spa2297_RS26890 3f4718f477bc8cd7d61331168ecd5455 241 SUPERFAMILY SSF52467 5 240 6.07E-73 T 16-09-2016 IPR029035 DHS-like NAD/FAD-binding domain Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 Pfam PF00704 Glycosyl hydrolases family 18 55 256 2.7E-19 T 16-09-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 PANTHER PTHR11177 24 352 6.8E-30 T 16-09-2016 Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 SMART SM00636 53 342 0.0036 T 16-09-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 SUPERFAMILY SSF51445 52 349 6.21E-44 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 PANTHER PTHR11177:SF195 24 352 6.8E-30 T 16-09-2016 Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 Gene3D G3DSA:3.20.20.80 53 349 2.4E-41 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS10555 e142621df4e62799db6341ad5fc370a4 359 ProSitePatterns PS01095 Chitinases family 18 active site. 167 175 - T 16-09-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 111 357 5.5E-92 T 16-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 358 34.948 T 16-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 16-09-2016 IPR000808 Mrp, conserved site GO:0005524 Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 PANTHER PTHR23264:SF19 1 357 1.0E-147 T 16-09-2016 Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 Pfam PF01883 Domain of unknown function DUF59 4 76 2.3E-17 T 16-09-2016 IPR002744 Domain of unknown function DUF59 Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 Gene3D G3DSA:3.40.50.300 101 356 3.2E-89 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 PANTHER PTHR23264 1 357 1.0E-147 T 16-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 SUPERFAMILY SSF117916 1 88 3.6E-24 T 16-09-2016 Spa2297_RS21730 2a9d251ebfc6d54673bcfdda6fd20fbf 377 SUPERFAMILY SSF52540 111 360 1.39E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.0E-33 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 SMART SM00244 22 180 1.9E-62 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PANTHER PTHR10264 17 249 4.6E-95 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 SUPERFAMILY SSF117892 54 187 1.7E-40 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 175 196 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 132 155 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 29 51 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 112 129 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 200 223 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 77 98 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PRINTS PR00721 Stomatin signature 156 174 7.2E-63 T 16-09-2016 IPR001972 Stomatin family GO:0016020 Spa2297_RS25465 7890c618c2bb78044d46dc6d2291f956 258 PANTHER PTHR10264:SF60 17 249 4.6E-95 T 16-09-2016 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 322 337 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 92 103 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 193 215 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 156 171 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 276 287 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 352 363 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 294 321 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 139 155 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00359 B-class P450 signature 343 352 2.0E-51 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 SUPERFAMILY SSF48264 8 402 3.67E-85 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 Pfam PF00067 Cytochrome P450 224 372 1.0E-16 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 Gene3D G3DSA:1.10.630.10 7 402 2.1E-111 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00385 P450 superfamily signature 276 287 5.9E-5 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00385 P450 superfamily signature 239 256 5.9E-5 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00385 P450 superfamily signature 343 352 5.9E-5 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PRINTS PR00385 P450 superfamily signature 352 363 5.9E-5 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS02870 cd75cb565196a343f69dce62163da023 402 PANTHER PTHR11712 18 402 1.5E-84 T 16-09-2016 Spa2297_RS09725 48b4c7ee3c3f971ff807b44cab0fe626 291 PIRSF PIRSF037395 16 280 1.1E-120 T 16-09-2016 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 Spa2297_RS09725 48b4c7ee3c3f971ff807b44cab0fe626 291 Pfam PF12822 Protein of unknown function (DUF3816) 87 256 1.3E-19 T 16-09-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 Spa2297_RS20280 3d4f40862511475b3949fda0e90924bd 788 PANTHER PTHR30634:SF10 2 778 0.0 T 16-09-2016 Spa2297_RS20280 3d4f40862511475b3949fda0e90924bd 788 PANTHER PTHR30634 2 778 0.0 T 16-09-2016 Spa2297_RS30055 9fba0e81224bbb1f20b9a0749b309acc 131 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 3 128 2.1E-50 T 16-09-2016 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative Spa2297_RS30055 9fba0e81224bbb1f20b9a0749b309acc 131 Gene3D G3DSA:2.30.110.10 4 126 1.8E-15 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS30055 9fba0e81224bbb1f20b9a0749b309acc 131 SUPERFAMILY SSF50475 2 126 3.76E-19 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS30055 9fba0e81224bbb1f20b9a0749b309acc 131 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 84 6.1E-6 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.3E-231 T 16-09-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 PANTHER PTHR42307:SF1 1 453 0.0 T 16-09-2016 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 PANTHER PTHR42307 1 453 0.0 T 16-09-2016 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 Pfam PF03136 Pup-ligase protein 4 423 8.4E-157 T 16-09-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.193 T 16-09-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS06355 2a35dfa3738cabfdc9c0e0bc4e7736c5 453 PIRSF PIRSF018077 1 453 4.3E-181 T 16-09-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 Spa2297_RS20075 f9b31e88f8158a595f65dace35a2f905 247 SUPERFAMILY SSF88713 55 240 2.47E-25 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS20075 f9b31e88f8158a595f65dace35a2f905 247 Gene3D G3DSA:3.20.20.370 54 241 1.4E-22 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS20075 f9b31e88f8158a595f65dace35a2f905 247 Pfam PF01522 Polysaccharide deacetylase 64 182 5.0E-18 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 28 397 6.0E-97 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 PANTHER PTHR30341 7 413 3.2E-189 T 16-09-2016 Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 Gene3D G3DSA:1.20.1530.10 23 405 4.0E-134 T 16-09-2016 IPR023171 Na/H antiporter domain Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 23 405 20.638 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 PANTHER PTHR30341:SF0 7 413 3.2E-189 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS17895 deecc83dca9f755a130f68bd20b98f45 475 Pfam PF06965 Na+/H+ antiporter 1 25 399 1.5E-131 T 16-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Spa2297_RS17225 2e0efee809d717a0b5f4faf70fc7ad77 174 Gene3D G3DSA:3.90.420.10 16 95 2.5E-10 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS17225 2e0efee809d717a0b5f4faf70fc7ad77 174 Pfam PF00174 Oxidoreductase molybdopterin binding domain 16 126 2.2E-6 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS17225 2e0efee809d717a0b5f4faf70fc7ad77 174 SUPERFAMILY SSF56524 17 153 3.53E-16 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 SUPERFAMILY SSF46689 219 267 3.32E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 SUPERFAMILY SSF46689 169 217 3.85E-5 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 SUPERFAMILY SSF51215 25 141 1.83E-12 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 Pfam PF12833 Helix-turn-helix domain 190 266 3.3E-19 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 PANTHER PTHR11019:SF75 1 265 1.4E-90 T 16-09-2016 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 SMART SM00342 183 265 2.7E-21 T 16-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 Gene3D G3DSA:1.10.10.60 166 221 6.8E-10 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 Gene3D G3DSA:2.60.120.280 21 129 1.4E-6 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 PANTHER PTHR11019 1 265 1.4E-90 T 16-09-2016 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 Pfam PF02311 AraC-like ligand binding domain 21 143 1.9E-21 T 16-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spa2297_RS15160 f763bc52e75b3c9edfd787754dcbf558 270 Gene3D G3DSA:1.10.10.60 222 267 2.0E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS32085 589412e8498d89459699205994d94af8 113 PANTHER PTHR34389 1 113 7.8E-45 T 16-09-2016 Spa2297_RS32085 589412e8498d89459699205994d94af8 113 SUPERFAMILY SSF54909 8 113 1.98E-27 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS32085 589412e8498d89459699205994d94af8 113 PANTHER PTHR34389:SF3 1 113 7.8E-45 T 16-09-2016 Spa2297_RS32085 589412e8498d89459699205994d94af8 113 Pfam PF05336 Domain of unknown function (DUF718) 9 112 1.9E-31 T 16-09-2016 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UniPathway: UPA00125 Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 Pfam PF00005 ABC transporter 40 172 1.4E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 PANTHER PTHR24220:SF454 22 261 3.8E-136 T 16-09-2016 Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 Gene3D G3DSA:3.40.50.300 21 227 8.3E-65 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 SUPERFAMILY SSF52540 23 237 6.75E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 SMART SM00382 49 222 4.7E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 PANTHER PTHR24220 22 261 3.8E-136 T 16-09-2016 Spa2297_RS25750 01746e2a518b86a34f0dc4e2c71215f3 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS06095 2c2f7ae07b9cc578346a99d30d16bf91 206 PANTHER PTHR23029 22 186 8.7E-17 T 16-09-2016 Spa2297_RS06095 2c2f7ae07b9cc578346a99d30d16bf91 206 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 23 186 2.0E-25 T 16-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 Spa2297_RS06095 2c2f7ae07b9cc578346a99d30d16bf91 206 SUPERFAMILY SSF53254 17 192 4.07E-31 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS06095 2c2f7ae07b9cc578346a99d30d16bf91 206 Gene3D G3DSA:3.40.50.1240 22 186 4.3E-24 T 16-09-2016 IPR029033 Histidine phosphatase superfamily Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 330 5.6E-84 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 Gene3D G3DSA:3.40.718.10 3 330 2.9E-100 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 SMART SM01329 3 337 2.1E-124 T 16-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 PANTHER PTHR11835:SF49 3 337 9.5E-109 T 16-09-2016 Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 SUPERFAMILY SSF53659 2 341 6.14E-96 T 16-09-2016 Spa2297_RS02885 645115b7a0297e3b634983e2ef084007 341 PANTHER PTHR11835 3 337 9.5E-109 T 16-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 Spa2297_RS23465 42c3ee3244c8bb89a3ac8c711da52502 137 SUPERFAMILY SSF103196 2 125 4.84E-32 T 16-09-2016 Spa2297_RS23465 42c3ee3244c8bb89a3ac8c711da52502 137 PANTHER PTHR36222 1 137 3.9E-56 T 16-09-2016 Spa2297_RS23465 42c3ee3244c8bb89a3ac8c711da52502 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.2E-25 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS23465 42c3ee3244c8bb89a3ac8c711da52502 137 Gene3D G3DSA:3.30.450.30 3 123 3.3E-25 T 16-09-2016 Spa2297_RS23465 42c3ee3244c8bb89a3ac8c711da52502 137 SMART SM00960 9 99 3.9E-33 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 18.012 T 16-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 PANTHER PTHR10916 6 66 9.6E-28 T 16-09-2016 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 SUPERFAMILY SSF46561 5 67 3.79E-24 T 16-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 16-09-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 Pfam PF00831 Ribosomal L29 protein 8 64 3.1E-26 T 16-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 PANTHER PTHR10916:SF0 6 66 9.6E-28 T 16-09-2016 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 Gene3D G3DSA:1.10.287.310 6 69 1.5E-31 T 16-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19835 51590c4d70f8f2cd0f8418a1596cd606 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 3.9E-22 T 16-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 Gene3D G3DSA:2.60.200.30 169 289 1.4E-32 T 16-09-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 PANTHER PTHR20275 165 314 2.0E-65 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 PANTHER PTHR20275 3 136 2.0E-65 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 Gene3D G3DSA:3.40.50.10330 3 132 1.8E-26 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 Hamap MF_00361 NAD kinase [nadK]. 4 315 27.574 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 SUPERFAMILY SSF111331 5 133 1.01E-61 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 SUPERFAMILY SSF111331 167 314 1.01E-61 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS00445 ee6d0fd500df891902d0f97798cf8a41 364 Pfam PF01513 ATP-NAD kinase 54 299 4.5E-44 T 16-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 Gene3D G3DSA:3.90.226.10 10 215 2.3E-57 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 PANTHER PTHR11941 2 272 3.3E-180 T 16-09-2016 Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 274 2.0E-49 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 SUPERFAMILY SSF52096 11 275 4.81E-76 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 16-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 Gene3D G3DSA:1.10.12.10 217 275 2.8E-23 T 16-09-2016 IPR014748 Crontonase, C-terminal Spa2297_RS25130 f992cd793ca4af34536c4e6e166bb797 275 PANTHER PTHR11941:SF90 2 272 3.3E-180 T 16-09-2016 Spa2297_RS11410 04493fe210008bed8c0ca766ef6c1520 91 Pfam PF03777 Small secreted domain (DUF320) 23 78 9.5E-30 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS25080 0309e535d7dc59e0a834a9a2754588ad 114 Gene3D G3DSA:1.10.287.1080 7 100 8.0E-21 T 16-09-2016 Spa2297_RS25080 0309e535d7dc59e0a834a9a2754588ad 114 SUPERFAMILY SSF101386 3 110 5.23E-34 T 16-09-2016 Spa2297_RS25080 0309e535d7dc59e0a834a9a2754588ad 114 Pfam PF12643 MazG-like family 37 112 1.0E-9 T 16-09-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12 Spa2297_RS25080 0309e535d7dc59e0a834a9a2754588ad 114 PANTHER PTHR14552 7 113 1.9E-31 T 16-09-2016 Spa2297_RS25080 0309e535d7dc59e0a834a9a2754588ad 114 PIRSF PIRSF029826 1 114 1.7E-40 T 16-09-2016 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 Spa2297_RS02760 1f1dfc6c9b7c28f039de011f47de895c 251 PANTHER PTHR17630 6 241 1.4E-76 T 16-09-2016 Spa2297_RS02760 1f1dfc6c9b7c28f039de011f47de895c 251 PANTHER PTHR17630:SF51 6 241 1.4E-76 T 16-09-2016 Spa2297_RS02760 1f1dfc6c9b7c28f039de011f47de895c 251 Pfam PF01738 Dienelactone hydrolase family 16 239 3.2E-37 T 16-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 Spa2297_RS02760 1f1dfc6c9b7c28f039de011f47de895c 251 SUPERFAMILY SSF53474 1 241 2.63E-41 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02760 1f1dfc6c9b7c28f039de011f47de895c 251 Gene3D G3DSA:3.40.50.1820 4 243 1.1E-42 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS22075 79e544300324a874a6c2eccefef59e82 419 SUPERFAMILY SSF109604 243 407 4.83E-10 T 16-09-2016 Spa2297_RS22075 79e544300324a874a6c2eccefef59e82 419 Gene3D G3DSA:1.10.3210.10 264 370 2.2E-7 T 16-09-2016 IPR006674 HD domain Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Pfam PF03471 Transporter associated domain 362 430 1.1E-18 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Pfam PF01595 Domain of unknown function DUF21 8 200 2.1E-32 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 SUPERFAMILY SSF54631 209 345 1.39E-25 T 16-09-2016 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Pfam PF00571 CBS domain 218 271 0.0047 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Pfam PF00571 CBS domain 291 334 0.0052 T 16-09-2016 IPR000644 CBS domain Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 SMART SM01091 356 433 2.4E-22 T 16-09-2016 IPR005170 Transporter-associated domain Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 PANTHER PTHR22777 4 432 2.9E-266 T 16-09-2016 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 SUPERFAMILY SSF56176 362 437 7.63E-18 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Gene3D G3DSA:3.10.580.10 208 329 1.5E-18 T 16-09-2016 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 Gene3D G3DSA:3.30.465.10 330 431 1.4E-22 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS17110 c4f1fc5b822909dc2ae757df0279c3c6 449 PANTHER PTHR22777:SF5 4 432 2.9E-266 T 16-09-2016 Spa2297_RS07080 97c0cb3c3cc8609e82fc486d75ab6cf6 231 Pfam PF14559 Tetratricopeptide repeat 127 185 2.4E-7 T 16-09-2016 Spa2297_RS07080 97c0cb3c3cc8609e82fc486d75ab6cf6 231 Gene3D G3DSA:1.25.40.10 24 100 2.8E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS07080 97c0cb3c3cc8609e82fc486d75ab6cf6 231 SUPERFAMILY SSF48452 27 183 7.15E-9 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS07080 97c0cb3c3cc8609e82fc486d75ab6cf6 231 Gene3D G3DSA:1.25.40.10 126 197 6.1E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS07080 97c0cb3c3cc8609e82fc486d75ab6cf6 231 Pfam PF13432 Tetratricopeptide repeat 54 98 0.015 T 16-09-2016 Spa2297_RS17910 bde5534de382f72b6a6e0e3f2bcfa912 426 Gene3D G3DSA:3.20.20.370 68 382 5.9E-13 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS17910 bde5534de382f72b6a6e0e3f2bcfa912 426 SUPERFAMILY SSF88713 81 123 5.28E-26 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS17910 bde5534de382f72b6a6e0e3f2bcfa912 426 SUPERFAMILY SSF88713 157 382 5.28E-26 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 PANTHER PTHR24362 5 273 9.1E-78 T 16-09-2016 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 Gene3D G3DSA:3.30.200.20 6 81 1.2E-20 T 16-09-2016 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 SUPERFAMILY SSF56112 7 269 1.6E-65 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 Gene3D G3DSA:1.10.510.10 82 263 7.1E-45 T 16-09-2016 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 SMART SM00220 13 266 1.4E-58 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 PANTHER PTHR24362:SF160 5 273 9.1E-78 T 16-09-2016 Spa2297_RS09570 3fbf2ce80014b1de365b819e9a2676e1 526 Pfam PF00069 Protein kinase domain 15 262 2.5E-44 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 SUPERFAMILY SSF46911 7 75 1.44E-25 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 17 75 1.7E-23 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 1.8E-17 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 1.8E-17 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 1.8E-17 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 1.8E-17 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 74 5.0E-12 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 16-09-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 Gene3D G3DSA:4.10.640.10 12 75 3.1E-29 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 77 20.013 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 Pfam PF01084 Ribosomal protein S18 23 72 5.6E-24 T 16-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS18085 de8b8fbd67183ab8905579146f4a453d 77 PANTHER PTHR13479 2 77 3.7E-26 T 16-09-2016 Spa2297_RS03875 a5808c8bd7399dad04b9a5ac3c9cd1da 247 PANTHER PTHR30269 2 243 2.6E-58 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS03875 a5808c8bd7399dad04b9a5ac3c9cd1da 247 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 1.3E-46 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS03875 a5808c8bd7399dad04b9a5ac3c9cd1da 247 PANTHER PTHR30269:SF14 2 243 2.6E-58 T 16-09-2016 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 ProSitePatterns PS01219 Ammonium transporters signature. 172 197 - T 16-09-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 Gene3D G3DSA:1.10.3430.10 12 398 1.3E-129 T 16-09-2016 IPR029020 Ammonium/urea transporter Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 PANTHER PTHR11730 10 423 1.6E-179 T 16-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 Pfam PF00909 Ammonium Transporter Family 20 417 6.2E-123 T 16-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 PANTHER PTHR11730:SF17 10 423 1.6E-179 T 16-09-2016 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 TIGRFAM TIGR00836 amt: ammonium transporter 17 417 2.9E-131 T 16-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Spa2297_RS23710 bbbc4a50dbf7bf36c1822e6567a90a4f 448 SUPERFAMILY SSF111352 14 398 4.32E-118 T 16-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 Gene3D G3DSA:1.10.357.10 60 201 4.8E-13 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 PANTHER PTHR30055:SF54 1 182 1.4E-51 T 16-09-2016 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 Gene3D G3DSA:1.10.10.60 7 59 3.1E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 6.0E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 6.0E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 SUPERFAMILY SSF46689 7 74 4.49E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 PANTHER PTHR30055 1 182 1.4E-51 T 16-09-2016 Spa2297_RS15220 01ab27311defbc60c2f558b8b2a7a632 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 1.7E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 Gene3D G3DSA:1.10.1740.10 4 96 7.4E-13 T 16-09-2016 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 Pfam PF04542 Sigma-70 region 2 12 76 3.5E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 PANTHER PTHR30173 1 161 8.2E-45 T 16-09-2016 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 SUPERFAMILY SSF88946 4 89 3.92E-13 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 155 6.9E-16 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 PANTHER PTHR30173:SF31 1 161 8.2E-45 T 16-09-2016 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 SUPERFAMILY SSF88659 101 155 3.18E-11 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 Gene3D G3DSA:1.10.10.10 101 156 3.7E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17170 296a0250ad921fc1f038519b2a733a9f 163 Pfam PF08281 Sigma-70, region 4 101 151 1.5E-11 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 Gene3D G3DSA:2.60.120.260 32 156 1.6E-31 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 Pfam PF00754 F5/8 type C domain 38 150 5.3E-27 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 Pfam PF00754 F5/8 type C domain 176 288 1.0E-25 T 16-09-2016 IPR000421 Coagulation factor 5/8 C-terminal domain Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 Gene3D G3DSA:2.60.120.260 167 300 6.5E-30 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 SUPERFAMILY SSF49785 34 155 1.56E-29 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 PANTHER PTHR10066 444 847 7.1E-206 T 16-09-2016 Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 PANTHER PTHR10066:SF12 444 847 7.1E-206 T 16-09-2016 Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 SUPERFAMILY SSF51126 548 733 3.65E-8 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS30860 fb5830757e3af7edc4673f2fdd258f9b 847 SUPERFAMILY SSF49785 176 292 1.21E-28 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 Gene3D G3DSA:1.50.10.10 42 305 2.6E-16 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 PANTHER PTHR12145:SF14 141 353 5.6E-36 T 16-09-2016 Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 PANTHER PTHR12145 141 353 5.6E-36 T 16-09-2016 Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 SUPERFAMILY SSF48208 61 375 4.32E-31 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 Pfam PF03663 Glycosyl hydrolase family 76 41 384 2.0E-41 T 16-09-2016 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 Spa2297_RS00330 71a36c41b8dcbbf4a3efc40932e58872 401 PIRSF PIRSF021505 1 394 7.7E-121 T 16-09-2016 IPR014512 Predicted O-glycosyl hydrolase Spa2297_RS30280 0f4696d300630f2cdbad507d246bb031 175 Pfam PF03259 Roadblock/LC7 domain 9 96 1.2E-17 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS30280 0f4696d300630f2cdbad507d246bb031 175 SUPERFAMILY SSF103196 9 120 2.44E-22 T 16-09-2016 Spa2297_RS30280 0f4696d300630f2cdbad507d246bb031 175 Gene3D G3DSA:3.30.450.30 6 121 2.2E-26 T 16-09-2016 Spa2297_RS30280 0f4696d300630f2cdbad507d246bb031 175 SMART SM00960 8 96 2.4E-17 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 PANTHER PTHR24220:SF559 10 228 1.7E-118 T 16-09-2016 Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 SMART SM00382 33 221 8.4E-19 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 PANTHER PTHR24220 10 228 1.7E-118 T 16-09-2016 Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 SUPERFAMILY SSF52540 8 225 3.3E-63 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 Pfam PF00005 ABC transporter 24 172 5.7E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS21315 89b375100f8e76dc5822237793af6860 229 Gene3D G3DSA:3.40.50.300 7 222 3.9E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 Pfam PF07690 Major Facilitator Superfamily 32 375 5.9E-23 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 PANTHER PTHR23517 3 410 1.0E-136 T 16-09-2016 Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 Gene3D G3DSA:1.20.1250.20 224 406 5.4E-12 T 16-09-2016 Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 Gene3D G3DSA:1.20.1250.20 24 206 2.8E-21 T 16-09-2016 Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 SUPERFAMILY SSF103473 24 407 5.49E-37 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27615 94ee9d9f3cb81d163fb092fbd241e390 411 PANTHER PTHR23517:SF2 3 410 1.0E-136 T 16-09-2016 Spa2297_RS22070 79d4169daf5bd93ce2cadc6c735743d4 448 SMART SM00471 242 377 1.1E-11 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS22070 79d4169daf5bd93ce2cadc6c735743d4 448 Pfam PF01966 HD domain 248 368 8.9E-20 T 16-09-2016 IPR006674 HD domain Spa2297_RS22070 79d4169daf5bd93ce2cadc6c735743d4 448 TIGRFAM TIGR00277 HDIG: HDIG domain 247 336 7.6E-8 T 16-09-2016 IPR006675 HDIG domain Spa2297_RS22070 79d4169daf5bd93ce2cadc6c735743d4 448 SUPERFAMILY SSF109604 231 405 1.65E-39 T 16-09-2016 Spa2297_RS22070 79d4169daf5bd93ce2cadc6c735743d4 448 Gene3D G3DSA:1.10.3210.10 245 404 1.4E-21 T 16-09-2016 IPR006674 HD domain Spa2297_RS04960 7dcaa2d944b323c09c972f2d1b7718ff 155 SUPERFAMILY SSF50475 7 150 1.48E-29 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04960 7dcaa2d944b323c09c972f2d1b7718ff 155 Gene3D G3DSA:2.30.110.10 10 151 1.2E-34 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS04960 7dcaa2d944b323c09c972f2d1b7718ff 155 PANTHER PTHR35176:SF3 3 154 7.4E-52 T 16-09-2016 Spa2297_RS04960 7dcaa2d944b323c09c972f2d1b7718ff 155 PANTHER PTHR35176 3 154 7.4E-52 T 16-09-2016 Spa2297_RS04960 7dcaa2d944b323c09c972f2d1b7718ff 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 100 3.2E-17 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 79 84 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 SMART SM00020 35 272 3.8E-60 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 Gene3D G3DSA:2.40.10.10 36 75 3.6E-11 T 16-09-2016 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 PANTHER PTHR24276 7 269 2.7E-68 T 16-09-2016 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 Gene3D G3DSA:2.40.10.10 76 140 1.3E-12 T 16-09-2016 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 227 238 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 SUPERFAMILY SSF50494 15 269 6.01E-58 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 Gene3D G3DSA:2.40.10.10 141 269 7.6E-37 T 16-09-2016 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 69 84 4.9E-11 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 132 146 4.9E-11 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 226 238 4.9E-11 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS24660 c9061ca10581052ddecd592b05b80904 288 Pfam PF00089 Trypsin 36 269 8.7E-49 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 PANTHER PTHR31438:SF3 1 222 6.0E-105 T 16-09-2016 Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 Pfam PF13523 Acetyltransferase (GNAT) domain 61 207 3.5E-46 T 16-09-2016 Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 SMART SM01006 58 106 1.6E-12 T 16-09-2016 IPR019432 Siderophore biosynthesis protein, conserved domain Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 Gene3D G3DSA:3.40.630.30 55 219 1.3E-48 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 PANTHER PTHR31438 1 222 6.0E-105 T 16-09-2016 Spa2297_RS24560 126c78f3fb8163d68d3900d4cea263dc 223 SUPERFAMILY SSF55729 54 219 3.09E-44 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 PANTHER PTHR30476:SF0 2 162 4.2E-90 T 16-09-2016 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 PANTHER PTHR30476 2 162 4.2E-90 T 16-09-2016 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 9.4E-62 T 16-09-2016 IPR007551 Protein of unknown function DUF520 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.998 T 16-09-2016 IPR007551 Protein of unknown function DUF520 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 SUPERFAMILY SSF89963 5 87 5.89E-29 T 16-09-2016 IPR007551 Protein of unknown function DUF520 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 Gene3D G3DSA:3.30.70.860 97 162 5.8E-30 T 16-09-2016 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 Gene3D G3DSA:3.30.70.990 11 96 7.7E-31 T 16-09-2016 Spa2297_RS19520 2e00cc75e89ca9915824ab1e4a7e1717 162 SUPERFAMILY SSF89963 90 162 3.66E-24 T 16-09-2016 IPR007551 Protein of unknown function DUF520 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 PANTHER PTHR23501 275 486 5.0E-244 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 SUPERFAMILY SSF103473 271 484 1.7E-34 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 SUPERFAMILY SSF103473 29 216 1.7E-34 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 PANTHER PTHR23501:SF91 1 259 5.0E-244 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 PANTHER PTHR23501 1 259 5.0E-244 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 Gene3D G3DSA:1.20.1250.20 44 209 8.1E-22 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 Gene3D G3DSA:1.20.1250.20 291 483 2.1E-5 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 PANTHER PTHR23501:SF91 275 486 5.0E-244 T 16-09-2016 Spa2297_RS12600 c6a78cad744fbdebc5cae72a8ce1bb22 486 Pfam PF07690 Major Facilitator Superfamily 45 429 6.8E-32 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01500 97e089fde9b7f612be859f53fd466a87 178 PANTHER PTHR11080 3 177 2.2E-39 T 16-09-2016 Spa2297_RS01500 97e089fde9b7f612be859f53fd466a87 178 Gene3D G3DSA:3.40.50.850 2 176 2.8E-44 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS01500 97e089fde9b7f612be859f53fd466a87 178 SUPERFAMILY SSF52499 2 176 5.89E-46 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS01500 97e089fde9b7f612be859f53fd466a87 178 Pfam PF00857 Isochorismatase family 4 173 3.4E-33 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS02715 edbd75755c14cf507506772626e350ee 200 Pfam PF01738 Dienelactone hydrolase family 4 191 1.9E-15 T 16-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 Spa2297_RS02715 edbd75755c14cf507506772626e350ee 200 SUPERFAMILY SSF53474 4 190 1.22E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02715 edbd75755c14cf507506772626e350ee 200 Gene3D G3DSA:3.40.50.1820 4 190 1.9E-18 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 SUPERFAMILY SSF50475 24 222 5.58E-46 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 PANTHER PTHR10851 25 222 1.2E-62 T 16-09-2016 Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 Gene3D G3DSA:2.30.110.10 26 222 1.0E-55 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 PIRSF PIRSF000190 2 222 1.3E-58 T 16-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 124 4.3E-19 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS14360 da2a212337961dd1a0997dc19971d7cb 222 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 180 222 8.5E-10 T 16-09-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS13115 2cabd8058a12059eb4a60e8ce32ab71e 124 Pfam PF12005 Protein of unknown function (DUF3499) 4 120 5.4E-47 T 16-09-2016 IPR021888 Protein of unknown function DUF3499 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 SUPERFAMILY SSF54292 20 96 9.7E-25 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 Gene3D G3DSA:1.10.150.120 93 185 1.7E-29 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 24 70 1.2E-7 T 16-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 PANTHER PTHR11908 157 183 6.5E-36 T 16-09-2016 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 Pfam PF01799 [2Fe-2S] binding domain 91 182 3.8E-29 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 SUPERFAMILY SSF47741 103 185 8.77E-27 T 16-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 57 65 - T 16-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 PANTHER PTHR11908 17 140 6.5E-36 T 16-09-2016 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 PANTHER PTHR11908:SF66 157 183 6.5E-36 T 16-09-2016 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 PANTHER PTHR11908:SF66 17 140 6.5E-36 T 16-09-2016 Spa2297_RS30250 98b927f2127a7e55954b0a16faaf8a55 187 Gene3D G3DSA:3.10.20.30 19 92 6.3E-31 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS02190 6161a35f23faf375d0d473e4dc21f4bc 122 PANTHER PTHR35908 1 113 5.9E-35 T 16-09-2016 Spa2297_RS02190 6161a35f23faf375d0d473e4dc21f4bc 122 SUPERFAMILY SSF54593 1 114 1.83E-11 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02190 6161a35f23faf375d0d473e4dc21f4bc 122 PANTHER PTHR35908:SF1 1 113 5.9E-35 T 16-09-2016 Spa2297_RS02190 6161a35f23faf375d0d473e4dc21f4bc 122 Gene3D G3DSA:3.10.180.10 7 114 1.2E-7 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 Pfam PF05787 Bacterial protein of unknown function (DUF839) 60 474 7.6E-85 T 16-09-2016 IPR008557 Protein of unknown function DUF839 Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 PANTHER PTHR35399:SF1 1 486 3.6E-185 T 16-09-2016 Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 PANTHER PTHR35399 1 486 3.6E-185 T 16-09-2016 Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 Gene3D G3DSA:2.130.10.10 319 468 9.8E-7 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 SUPERFAMILY SSF63829 337 474 2.35E-10 T 16-09-2016 Spa2297_RS07605 4d5caaa235710365d3a4f7a35a6cfc20 488 SUPERFAMILY SSF63829 202 274 2.35E-10 T 16-09-2016 Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 PANTHER PTHR11019 4 176 1.3E-69 T 16-09-2016 Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 173 1.8E-44 T 16-09-2016 IPR006286 Peptidase C56, PfpI GO:0016798 Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 Pfam PF01965 DJ-1/PfpI family 1 173 3.3E-49 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 PANTHER PTHR11019:SF115 4 176 1.3E-69 T 16-09-2016 Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 Gene3D G3DSA:3.40.50.880 1 177 7.8E-47 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS27135 9e5414d8d6e9b7e709f1cd3cbcb14bf7 180 SUPERFAMILY SSF52317 1 175 8.1E-39 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.727 T 16-09-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 4.6E-44 T 16-09-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 Gene3D G3DSA:3.40.50.2000 2 187 1.3E-60 T 16-09-2016 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 4.4E-43 T 16-09-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 PANTHER PTHR21015:SF22 3 361 6.8E-115 T 16-09-2016 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 PANTHER PTHR21015 3 361 6.8E-115 T 16-09-2016 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 5.1E-87 T 16-09-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 Gene3D G3DSA:3.40.50.2000 188 343 2.2E-18 T 16-09-2016 Spa2297_RS08525 1f6667f880acda7abc853e2e2f06fb51 364 SUPERFAMILY SSF53756 2 358 2.72E-100 T 16-09-2016 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 PANTHER PTHR13789:SF246 8 384 5.7E-179 T 16-09-2016 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 Gene3D G3DSA:3.50.50.60 281 351 2.1E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 Gene3D G3DSA:3.50.50.60 16 186 2.1E-26 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 PANTHER PTHR13789 8 384 5.7E-179 T 16-09-2016 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 SUPERFAMILY SSF51905 16 180 3.1E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 SUPERFAMILY SSF51905 280 386 3.1E-44 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 Pfam PF01494 FAD binding domain 16 353 5.5E-10 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 6.6E-9 T 16-09-2016 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 6.6E-9 T 16-09-2016 Spa2297_RS31680 d3a27f44e003eb1b7da242b63a91534a 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 6.6E-9 T 16-09-2016 Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 Gene3D G3DSA:3.30.420.10 3 186 1.5E-39 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 SMART SM00479 8 189 1.4E-20 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 PANTHER PTHR30231 1 237 6.1E-93 T 16-09-2016 Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 PANTHER PTHR30231:SF9 1 237 6.1E-93 T 16-09-2016 Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 SUPERFAMILY SSF53098 4 204 3.29E-41 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS05830 0e85ec101b44fcde5f86ef26630aff3e 241 Pfam PF00929 Exonuclease 11 179 1.7E-15 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS11790 1e95334a8c623ba65a362d99b88bb3fc 426 PANTHER PTHR23024 52 123 2.6E-42 T 16-09-2016 Spa2297_RS11790 1e95334a8c623ba65a362d99b88bb3fc 426 PANTHER PTHR23024:SF215 52 123 2.6E-42 T 16-09-2016 Spa2297_RS11790 1e95334a8c623ba65a362d99b88bb3fc 426 SUPERFAMILY SSF51905 9 252 1.14E-18 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS11790 1e95334a8c623ba65a362d99b88bb3fc 426 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 340 3.2E-124 T 16-09-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase Spa2297_RS11790 1e95334a8c623ba65a362d99b88bb3fc 426 Gene3D G3DSA:3.50.50.60 92 224 4.2E-12 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 SUPERFAMILY SSF52540 1 139 1.33E-27 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 SUPERFAMILY SSF57716 144 195 8.55E-8 T 16-09-2016 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 Hamap MF_00124 Thymidine kinase [tdk]. 1 195 27.869 T 16-09-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 Gene3D G3DSA:3.30.60.20 144 194 1.1E-4 T 16-09-2016 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 Pfam PF00265 Thymidine kinase 4 192 8.1E-23 T 16-09-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 PIRSF PIRSF035805 1 205 1.2E-35 T 16-09-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 Spa2297_RS24785 6d4dd36e08aa8206dcedf65678ef0210 216 Gene3D G3DSA:3.40.50.300 2 123 8.2E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Pfam PF07690 Major Facilitator Superfamily 44 437 1.4E-54 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF49464 552 629 1.14E-8 T 16-09-2016 IPR008969 Carboxypeptidase-like, regulatory domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF49452 629 713 3.53E-12 T 16-09-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PANTHER PTHR23501 8 544 8.1E-219 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF49478 719 787 1.88E-10 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:1.20.1250.20 41 221 1.4E-32 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:1.20.1250.20 296 460 6.0E-19 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:1.20.1250.20 497 524 6.0E-19 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:2.60.40.10 721 773 3.1E-10 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:2.60.40.1120 635 715 1.9E-13 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Gene3D G3DSA:2.60.40.1120 553 629 5.7E-7 T 16-09-2016 IPR014766 Carboxypeptidase, regulatory domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF103473 274 446 1.15E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF103473 23 221 1.15E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 SUPERFAMILY SSF103473 491 516 1.15E-73 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PANTHER PTHR23501:SF73 8 544 8.1E-219 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Pfam PF13620 Carboxypeptidase regulatory-like domain 719 795 1.1E-11 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Pfam PF13620 Carboxypeptidase regulatory-like domain 635 713 1.0E-14 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 Pfam PF13620 Carboxypeptidase regulatory-like domain 554 629 2.8E-9 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 153 6.6E-7 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PRINTS PR01036 Tetracycline resistance protein TetB signature 43 67 6.6E-7 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PRINTS PR01036 Tetracycline resistance protein TetB signature 163 187 6.6E-7 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 PRINTS PR01036 Tetracycline resistance protein TetB signature 228 246 6.6E-7 T 16-09-2016 Spa2297_RS26980 6139a4499be5d6b7b89e5701fda51030 799 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 40 448 3.2E-82 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 Gene3D G3DSA:3.20.20.30 4 300 9.6E-63 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 SUPERFAMILY SSF51679 3 300 3.53E-57 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 PANTHER PTHR30011 1 271 4.1E-72 T 16-09-2016 Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 282 2.1E-75 T 16-09-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 Pfam PF00296 Luciferase-like monooxygenase 19 264 1.1E-47 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS05480 751e03297bda33936e7fcf18c8315b44 309 PANTHER PTHR30011:SF5 1 271 4.1E-72 T 16-09-2016 Spa2297_RS01225 25bbad2b994b6f24fceb5b1569a7e3b8 313 PANTHER PTHR30193:SF6 8 313 1.6E-108 T 16-09-2016 Spa2297_RS01225 25bbad2b994b6f24fceb5b1569a7e3b8 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 310 2.6E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01225 25bbad2b994b6f24fceb5b1569a7e3b8 313 SUPERFAMILY SSF161098 77 303 8.9E-61 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01225 25bbad2b994b6f24fceb5b1569a7e3b8 313 PANTHER PTHR30193 8 313 1.6E-108 T 16-09-2016 Spa2297_RS01225 25bbad2b994b6f24fceb5b1569a7e3b8 313 Gene3D G3DSA:1.10.3720.10 84 312 2.0E-62 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 Gene3D G3DSA:2.60.130.10 80 232 1.4E-41 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 PANTHER PTHR33711:SF3 59 251 1.6E-73 T 16-09-2016 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 SMART SM00495 247 293 3.0E-10 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 SUPERFAMILY SSF51055 250 291 4.97E-15 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 PANTHER PTHR33711 59 251 1.6E-73 T 16-09-2016 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 Pfam PF00775 Dioxygenase 87 206 3.8E-16 T 16-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 Pfam PF02839 Carbohydrate binding domain 250 290 3.6E-8 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 Gene3D G3DSA:2.10.10.20 250 292 9.9E-23 T 16-09-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 Spa2297_RS16755 b00f77072f0c96d9125eadba67fab63c 294 SUPERFAMILY SSF49482 80 231 1.06E-43 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 16-09-2016 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 Pfam PF01250 Ribosomal protein S6 3 92 9.3E-29 T 16-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 Gene3D G3DSA:3.30.70.60 1 94 8.1E-35 T 16-09-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 PANTHER PTHR21011 1 92 1.3E-27 T 16-09-2016 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 4.2E-26 T 16-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 SUPERFAMILY SSF54995 1 94 3.01E-32 T 16-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS16440 9c49e9f8f584e8a202a49e83270ac7b2 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.388 T 16-09-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 PANTHER PTHR11732 253 318 2.1E-117 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 SUPERFAMILY SSF51430 1 317 1.26E-73 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 PANTHER PTHR11732:SF185 253 318 2.1E-117 T 16-09-2016 Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 PANTHER PTHR11732:SF185 1 237 2.1E-117 T 16-09-2016 Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 Pfam PF00248 Aldo/keto reductase family 16 315 5.0E-60 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 Gene3D G3DSA:3.20.20.100 1 316 2.0E-70 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS02255 b4bc65e3acda0440087a9d39c8f11095 327 PANTHER PTHR11732 1 237 2.1E-117 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS05315 c132581619bba67106584017089cae1d 223 PANTHER PTHR40078:SF1 13 221 1.4E-61 T 16-09-2016 Spa2297_RS05315 c132581619bba67106584017089cae1d 223 PANTHER PTHR40078 13 221 1.4E-61 T 16-09-2016 Spa2297_RS17240 8d2434c68c336914418d9c6679cc12cf 522 PANTHER PTHR33744 1 507 2.4E-34 T 16-09-2016 Spa2297_RS17240 8d2434c68c336914418d9c6679cc12cf 522 Pfam PF07905 Purine catabolism regulatory protein-like family 6 121 2.4E-18 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS17240 8d2434c68c336914418d9c6679cc12cf 522 Pfam PF13556 PucR C-terminal helix-turn-helix domain 440 497 1.1E-21 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS17240 8d2434c68c336914418d9c6679cc12cf 522 PANTHER PTHR33744:SF3 1 507 2.4E-34 T 16-09-2016 Spa2297_RS19635 33b793c67959fe83374e99db40b8c2a7 176 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 16-09-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19635 33b793c67959fe83374e99db40b8c2a7 176 Pfam PF00466 Ribosomal protein L10 4 98 5.7E-26 T 16-09-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Spa2297_RS19635 33b793c67959fe83374e99db40b8c2a7 176 SUPERFAMILY SSF160369 1 168 1.31E-52 T 16-09-2016 Spa2297_RS19635 33b793c67959fe83374e99db40b8c2a7 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.248 T 16-09-2016 IPR022973 Ribosomal protein L10 Spa2297_RS19635 33b793c67959fe83374e99db40b8c2a7 176 PANTHER PTHR11560 1 176 4.2E-53 T 16-09-2016 Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 PANTHER PTHR34135 1 163 5.4E-36 T 16-09-2016 Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 Gene3D G3DSA:3.20.20.80 2 182 3.6E-39 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 PANTHER PTHR34135:SF2 1 163 5.4E-36 T 16-09-2016 Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 SMART SM00641 2 102 3.9E-33 T 16-09-2016 IPR018077 Glycoside hydrolase, family 25 subgroup Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 Pfam PF01183 Glycosyl hydrolases family 25 5 165 1.0E-39 T 16-09-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 Spa2297_RS23100 360e9acf1c5bef3b8cb0111ba67d1bc7 185 SUPERFAMILY SSF51445 3 182 1.26E-34 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS19460 ac83c87035922a6346f960d38bbab823 322 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 321 22.355 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19460 ac83c87035922a6346f960d38bbab823 322 PANTHER PTHR11432 1 322 9.6E-102 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19460 ac83c87035922a6346f960d38bbab823 322 Pfam PF00146 NADH dehydrogenase 11 314 1.6E-100 T 16-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Spa2297_RS19460 ac83c87035922a6346f960d38bbab823 322 PANTHER PTHR11432:SF3 1 322 9.6E-102 T 16-09-2016 Spa2297_RS24690 feb933546d7acb8a6b19f39c63e69f82 191 PANTHER PTHR38441 63 184 3.5E-40 T 16-09-2016 Spa2297_RS24690 feb933546d7acb8a6b19f39c63e69f82 191 PANTHER PTHR38441:SF1 63 184 3.5E-40 T 16-09-2016 Spa2297_RS24690 feb933546d7acb8a6b19f39c63e69f82 191 Pfam PF04341 Protein of unknown function, DUF485 90 176 5.2E-28 T 16-09-2016 IPR007436 Protein of unknown function DUF485 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 SMART SM00644 302 441 8.9E-45 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 PANTHER PTHR30417 22 679 0.0 T 16-09-2016 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 SUPERFAMILY SSF55846 306 454 1.02E-37 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 PANTHER PTHR30417:SF1 22 679 0.0 T 16-09-2016 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 Gene3D G3DSA:3.40.80.10 303 453 1.2E-36 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 789 851 3.5E-7 T 16-09-2016 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 Gene3D G3DSA:2.115.10.10 691 820 1.1E-13 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 Gene3D G3DSA:2.115.10.10 824 940 2.7E-12 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 312 442 5.7E-21 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS08690 44349398d30971fe9db5617fe5241151 941 SUPERFAMILY SSF69318 666 925 5.75E-18 T 16-09-2016 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 PANTHER PTHR22911:SF54 1 283 1.2E-74 T 16-09-2016 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 SUPERFAMILY SSF103481 201 284 7.06E-9 T 16-09-2016 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 SUPERFAMILY SSF103481 39 133 1.12E-9 T 16-09-2016 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 Pfam PF00892 EamA-like transporter family 145 283 3.2E-9 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 Pfam PF00892 EamA-like transporter family 3 129 4.4E-9 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS04820 20aa1f28edcc76327131ecb47e2631fd 285 PANTHER PTHR22911 1 283 1.2E-74 T 16-09-2016 Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 Gene3D G3DSA:3.30.1440.10 7 183 2.0E-75 T 16-09-2016 IPR022803 Ribosomal protein L5 domain Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 PANTHER PTHR11994 6 184 4.0E-93 T 16-09-2016 Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 PIRSF PIRSF002161 1 185 1.1E-63 T 16-09-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 Pfam PF00281 Ribosomal protein L5 29 85 1.5E-28 T 16-09-2016 IPR031310 Ribosomal protein L5, N-terminal Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 Pfam PF00673 ribosomal L5P family C-terminus 89 182 8.2E-39 T 16-09-2016 IPR031309 Ribosomal protein L5, C-terminal Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 SUPERFAMILY SSF55282 8 183 5.89E-75 T 16-09-2016 IPR022803 Ribosomal protein L5 domain Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 6 184 43.45 T 16-09-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS19855 18f822fc4eefee502dde7564af9803e4 185 ProSitePatterns PS00358 Ribosomal protein L5 signature. 62 78 - T 16-09-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 PRINTS PR01217 Proline rich extensin signature 310 331 5.6E-9 T 16-09-2016 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 PRINTS PR01217 Proline rich extensin signature 350 367 5.6E-9 T 16-09-2016 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 PRINTS PR01217 Proline rich extensin signature 371 396 5.6E-9 T 16-09-2016 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 PRINTS PR01217 Proline rich extensin signature 331 347 5.6E-9 T 16-09-2016 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 Pfam PF13406 Transglycosylase SLT domain 190 231 1.5E-6 T 16-09-2016 IPR031304 Transglycosylase SLT domain 2 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 SUPERFAMILY SSF53955 98 269 3.09E-34 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 Gene3D G3DSA:1.10.530.10 190 255 2.7E-10 T 16-09-2016 Spa2297_RS10145 7d700254f9e946037c45e8b331e07f15 417 Gene3D G3DSA:1.10.530.10 128 154 2.7E-10 T 16-09-2016 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 PANTHER PTHR33695 19 191 5.4E-49 T 16-09-2016 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 PANTHER PTHR33695:SF1 19 191 5.4E-49 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 Pfam PF01252 Signal peptidase (SPase) II 48 185 1.7E-28 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 TIGRFAM TIGR00077 lspA: signal peptidase II 43 185 1.3E-22 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 166 182 6.5E-16 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 86 94 6.5E-16 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 128 143 6.5E-16 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 39 191 14.854 T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS08475 d82411668b31f82336f9bd0ec7e365c0 197 ProSitePatterns PS00855 Signal peptidases II signature. 131 143 - T 16-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 Gene3D G3DSA:1.10.260.40 14 75 2.9E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 SMART SM00530 21 77 3.2E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 Pfam PF13560 Helix-turn-helix domain 18 78 2.0E-15 T 16-09-2016 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 PANTHER PTHR10245:SF20 10 291 2.2E-124 T 16-09-2016 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 SUPERFAMILY SSF47413 14 75 1.89E-10 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00940 412f9505c726cba4f1595f66892250bb 291 PANTHER PTHR10245 10 291 2.2E-124 T 16-09-2016 Spa2297_RS26045 771c5098951a101d2f9edac4141ab9f5 170 Pfam PF02080 TrkA-C domain 99 158 1.5E-6 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS26045 771c5098951a101d2f9edac4141ab9f5 170 SUPERFAMILY SSF116726 89 157 2.22E-7 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS26045 771c5098951a101d2f9edac4141ab9f5 170 Gene3D G3DSA:3.30.70.1450 103 157 9.5E-6 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS15295 9ec0a475a00c277a536ca386c41b64d0 191 PANTHER PTHR15854 2 167 6.0E-98 T 16-09-2016 Spa2297_RS15295 9ec0a475a00c277a536ca386c41b64d0 191 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 1.6E-46 T 16-09-2016 IPR014878 Domain of unknown function DUF1794 Spa2297_RS15295 9ec0a475a00c277a536ca386c41b64d0 191 SUPERFAMILY SSF50814 7 165 1.8E-40 T 16-09-2016 IPR011038 Calycin-like Spa2297_RS15295 9ec0a475a00c277a536ca386c41b64d0 191 PANTHER PTHR15854:SF6 2 167 6.0E-98 T 16-09-2016 Spa2297_RS15295 9ec0a475a00c277a536ca386c41b64d0 191 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 31.434 T 16-09-2016 IPR022939 Uncharacterised protein family UPF0678 Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 SUPERFAMILY SSF53686 28 294 1.57E-43 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 PANTHER PTHR10314 29 338 1.7E-59 T 16-09-2016 Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 PANTHER PTHR10314:SF35 29 338 1.7E-59 T 16-09-2016 Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 281 7.8E-31 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 Gene3D G3DSA:3.40.50.1100 127 293 3.0E-26 T 16-09-2016 Spa2297_RS25010 ea3ecf57e6edc94d5f07fd7477ccb049 341 Gene3D G3DSA:3.40.50.1100 28 126 5.4E-14 T 16-09-2016 Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 Pfam PF01427 D-ala-D-ala dipeptidase 54 203 4.9E-18 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 Gene3D G3DSA:3.30.1380.10 16 202 1.4E-44 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 PANTHER PTHR22935 1 200 1.6E-44 T 16-09-2016 Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 PIRSF PIRSF026671 1 209 2.5E-42 T 16-09-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 PANTHER PTHR22935:SF73 1 200 1.6E-44 T 16-09-2016 Spa2297_RS03320 783ff3ddf46ffc511f9c180b99859bf8 226 SUPERFAMILY SSF55166 16 202 5.49E-41 T 16-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Spa2297_RS30995 24e5eb698aee204c588a0cc4015fc09d 271 Pfam PF04672 S-adenosyl methyltransferase 11 271 9.6E-109 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS30995 24e5eb698aee204c588a0cc4015fc09d 271 PIRSF PIRSF017393 1 271 8.5E-105 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS30995 24e5eb698aee204c588a0cc4015fc09d 271 SUPERFAMILY SSF53335 21 253 1.67E-45 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30995 24e5eb698aee204c588a0cc4015fc09d 271 Gene3D G3DSA:3.40.50.150 7 271 5.9E-106 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS21190 376aa70c80f9c93f21913c039ba52af4 299 Pfam PF00482 Type II secretion system (T2SS), protein F 156 281 1.3E-19 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS21190 376aa70c80f9c93f21913c039ba52af4 299 PANTHER PTHR35007:SF2 1 299 1.9E-86 T 16-09-2016 Spa2297_RS21190 376aa70c80f9c93f21913c039ba52af4 299 PANTHER PTHR35007 1 299 1.9E-86 T 16-09-2016 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 Pfam PF13377 Periplasmic binding protein-like domain 182 344 8.1E-42 T 16-09-2016 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 63 1.2E-13 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 SUPERFAMILY SSF53822 74 347 1.56E-78 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 Gene3D G3DSA:1.10.260.40 19 63 3.1E-16 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 Gene3D G3DSA:3.40.50.2300 188 319 1.1E-54 T 16-09-2016 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 SUPERFAMILY SSF47413 19 66 1.32E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 PANTHER PTHR30146 18 347 1.6E-206 T 16-09-2016 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 PANTHER PTHR30146:SF43 18 347 1.6E-206 T 16-09-2016 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 SMART SM00354 18 84 1.1E-11 T 16-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 Spa2297_RS20045 190e8c02ae8e7f6f4ef1165cbe989843 350 Gene3D G3DSA:3.40.50.2300 66 187 1.3E-27 T 16-09-2016 Spa2297_RS05995 636ca66e34df62f9e310e61cb5786195 165 PANTHER PTHR23091 1 157 2.7E-44 T 16-09-2016 Spa2297_RS05995 636ca66e34df62f9e310e61cb5786195 165 Pfam PF00583 Acetyltransferase (GNAT) family 61 138 2.4E-15 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS05995 636ca66e34df62f9e310e61cb5786195 165 SUPERFAMILY SSF55729 1 143 3.54E-28 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS05995 636ca66e34df62f9e310e61cb5786195 165 PANTHER PTHR23091:SF264 1 157 2.7E-44 T 16-09-2016 Spa2297_RS05995 636ca66e34df62f9e310e61cb5786195 165 Gene3D G3DSA:3.40.630.30 2 159 1.6E-31 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16040 32d21b23f6e085a3864b1a585abc28a9 729 PANTHER PTHR33908 329 674 6.7E-144 T 16-09-2016 Spa2297_RS16040 32d21b23f6e085a3864b1a585abc28a9 729 PANTHER PTHR33908 38 311 6.7E-144 T 16-09-2016 Spa2297_RS16040 32d21b23f6e085a3864b1a585abc28a9 729 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 110 267 8.8E-30 T 16-09-2016 Spa2297_RS16040 32d21b23f6e085a3864b1a585abc28a9 729 PANTHER PTHR33908:SF3 329 674 6.7E-144 T 16-09-2016 Spa2297_RS16040 32d21b23f6e085a3864b1a585abc28a9 729 PANTHER PTHR33908:SF3 38 311 6.7E-144 T 16-09-2016 Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 253 5.4E-60 T 16-09-2016 Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 Gene3D G3DSA:3.40.50.720 11 253 7.4E-79 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PANTHER PTHR24321 11 255 1.9E-59 T 16-09-2016 Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 SUPERFAMILY SSF51735 10 255 4.38E-73 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.0E-37 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PANTHER PTHR24321:SF6 11 255 1.9E-59 T 16-09-2016 Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.7E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.7E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS32080 894c265652f568e9053da2c65b5d9dc3 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.7E-10 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS05715 aed22e4af5cd3eda3b2604bceb5dad24 274 PANTHER PTHR11071:SF165 107 266 1.1E-59 T 16-09-2016 Spa2297_RS05715 aed22e4af5cd3eda3b2604bceb5dad24 274 PANTHER PTHR11071 107 266 1.1E-59 T 16-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 Spa2297_RS05715 aed22e4af5cd3eda3b2604bceb5dad24 274 Gene3D G3DSA:2.40.100.10 112 271 6.1E-36 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05715 aed22e4af5cd3eda3b2604bceb5dad24 274 SUPERFAMILY SSF50891 113 272 1.04E-35 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS05715 aed22e4af5cd3eda3b2604bceb5dad24 274 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 114 270 3.5E-28 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 Pfam PF00202 Aminotransferase class-III 22 116 8.8E-15 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 Pfam PF00202 Aminotransferase class-III 145 322 2.2E-22 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 PANTHER PTHR11986 21 400 4.2E-266 T 16-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 PANTHER PTHR11986:SF83 21 400 4.2E-266 T 16-09-2016 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 Gene3D G3DSA:3.40.640.10 57 297 5.0E-47 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 Gene3D G3DSA:3.90.1150.10 18 56 1.6E-19 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 Gene3D G3DSA:3.90.1150.10 299 393 1.6E-19 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS31715 58911895d2f6d1aa7dcdfbeee80eda65 421 SUPERFAMILY SSF53383 18 392 1.94E-78 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 66 84 - T 16-09-2016 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 Gene3D G3DSA:3.30.350.10 39 144 1.5E-37 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 Pfam PF00720 Subtilisin inhibitor-like 39 130 4.7E-38 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 38 144 32.695 T 16-09-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 43 132 5.0E-39 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 SUPERFAMILY SSF55399 38 144 3.27E-41 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 119 135 2.8E-29 T 16-09-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 102 118 2.8E-29 T 16-09-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 Spa2297_RS29905 abf6fe86fb25b21989f66d1d87cdc590 144 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 40 66 2.8E-29 T 16-09-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 Gene3D G3DSA:1.10.10.10 25 90 7.4E-23 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 PANTHER PTHR11751:SF394 81 410 3.0E-134 T 16-09-2016 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 SUPERFAMILY SSF53383 96 461 4.32E-70 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 Pfam PF00155 Aminotransferase class I and II 125 411 5.5E-16 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 PANTHER PTHR11751 81 410 3.0E-134 T 16-09-2016 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 SUPERFAMILY SSF46785 20 88 2.72E-18 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 84 1.9E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 Gene3D G3DSA:3.90.1150.10 350 446 1.2E-4 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 Gene3D G3DSA:3.40.640.10 142 349 8.7E-39 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 SMART SM00345 25 84 2.9E-16 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 4.8E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS20405 4a2fdc8673915e90c51fbc86f2ca09d9 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 4.8E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PANTHER PTHR24322:SF363 148 180 1.5E-15 T 16-09-2016 Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PANTHER PTHR24322:SF363 10 131 1.5E-15 T 16-09-2016 Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 Pfam PF00106 short chain dehydrogenase 8 186 1.1E-23 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.3E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.3E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.3E-8 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 Gene3D G3DSA:3.40.50.720 2 219 1.3E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PANTHER PTHR24322 10 131 1.5E-15 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 PANTHER PTHR24322 148 180 1.5E-15 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS00785 b7c2581b018bbc8add031830f299eb98 236 SUPERFAMILY SSF51735 2 218 9.06E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02010 274e323eb97d1180c5720b8f55e9feb0 453 SUPERFAMILY SSF56112 142 449 6.12E-21 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS02010 274e323eb97d1180c5720b8f55e9feb0 453 Gene3D G3DSA:3.90.1200.10 251 412 2.1E-8 T 16-09-2016 Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 PIRSF PIRSF000355 3 335 3.3E-97 T 16-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 Gene3D G3DSA:1.10.620.20 16 304 8.1E-96 T 16-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 SUPERFAMILY SSF47240 8 324 1.69E-88 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 PANTHER PTHR23409:SF18 16 337 1.3E-121 T 16-09-2016 Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 PANTHER PTHR23409 16 337 1.3E-121 T 16-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 Spa2297_RS22110 6333b497f0bed4db17193b1a34bcbf61 337 Pfam PF00268 Ribonucleotide reductase, small chain 16 300 3.8E-79 T 16-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 201 4.3E-18 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 Gene3D G3DSA:3.40.50.1110 3 213 1.4E-18 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 SUPERFAMILY SSF52266 63 213 1.16E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 SUPERFAMILY SSF52266 2 26 1.16E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 PANTHER PTHR30383 2 43 1.1E-25 T 16-09-2016 Spa2297_RS14585 f18b908b27d1f6b00f7dd4c55cfee4f4 226 PANTHER PTHR30383 59 222 1.1E-25 T 16-09-2016 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 PANTHER PTHR11953:SF0 3 245 4.5E-87 T 16-09-2016 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.4 T 16-09-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 SUPERFAMILY SSF55666 155 242 1.96E-25 T 16-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 PANTHER PTHR11953 3 245 4.5E-87 T 16-09-2016 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 SUPERFAMILY SSF54211 3 183 1.72E-45 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 16-09-2016 IPR018336 Ribonuclease PH, conserved site Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 Gene3D G3DSA:3.30.230.70 3 240 3.5E-33 T 16-09-2016 IPR027408 PNPase/RNase PH domain Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 1.1E-24 T 16-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 1.4E-116 T 16-09-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 Spa2297_RS12420 0acd5eebb898b8b96c4dd329017e8341 245 Pfam PF03725 3' exoribonuclease family, domain 2 162 226 2.2E-10 T 16-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 Spa2297_RS06650 4eac42eca25e2c3fb2e43702df3f6168 153 Pfam PF01575 MaoC like domain 15 131 3.4E-27 T 16-09-2016 IPR002539 MaoC-like domain Spa2297_RS06650 4eac42eca25e2c3fb2e43702df3f6168 153 SUPERFAMILY SSF54637 11 150 1.77E-40 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS06650 4eac42eca25e2c3fb2e43702df3f6168 153 Gene3D G3DSA:3.10.129.10 13 150 2.5E-38 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS06650 4eac42eca25e2c3fb2e43702df3f6168 153 PANTHER PTHR13078 4 149 9.5E-44 T 16-09-2016 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 SUPERFAMILY SSF55469 4 101 8.57E-8 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 Gene3D G3DSA:3.40.109.10 218 299 6.7E-16 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 Gene3D G3DSA:3.40.109.10 6 72 6.7E-16 T 16-09-2016 IPR000415 Nitroreductase-like GO:0016491 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 PANTHER PTHR23026:SF111 158 298 5.8E-22 T 16-09-2016 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 PANTHER PTHR23026:SF111 6 37 5.8E-22 T 16-09-2016 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 PANTHER PTHR23026 158 298 5.8E-22 T 16-09-2016 Spa2297_RS03960 0d12424852f14c7f13dd7ce685d2291d 313 PANTHER PTHR23026 6 37 5.8E-22 T 16-09-2016 Spa2297_RS11190 8bb9afc44fc7c581c4c12290b0c43cc9 165 PIRSF PIRSF034110 1 160 5.7E-49 T 16-09-2016 IPR009593 Protein of unknown function DUF1203 Spa2297_RS11190 8bb9afc44fc7c581c4c12290b0c43cc9 165 Pfam PF06718 Protein of unknown function (DUF1203) 36 159 1.1E-34 T 16-09-2016 IPR009593 Protein of unknown function DUF1203 Spa2297_RS03230 d3c94f249b657a89ca2f92bcb3bbfdc9 417 Pfam PF07394 Protein of unknown function (DUF1501) 251 397 1.4E-19 T 16-09-2016 IPR010869 Protein of unknown function DUF1501 Spa2297_RS20690 02e78b05f8f8f1e0cdc209f6b1810191 421 PANTHER PTHR32196:SF40 1 183 2.0E-155 T 16-09-2016 Spa2297_RS20690 02e78b05f8f8f1e0cdc209f6b1810191 421 PANTHER PTHR32196 210 382 2.0E-155 T 16-09-2016 Spa2297_RS20690 02e78b05f8f8f1e0cdc209f6b1810191 421 PANTHER PTHR32196 1 183 2.0E-155 T 16-09-2016 Spa2297_RS20690 02e78b05f8f8f1e0cdc209f6b1810191 421 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 347 3.3E-35 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS20690 02e78b05f8f8f1e0cdc209f6b1810191 421 PANTHER PTHR32196:SF40 210 382 2.0E-155 T 16-09-2016 Spa2297_RS30565 090e7dde4825560c6f7d5b37e1f633be 334 SUPERFAMILY SSF75005 81 264 1.57E-17 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS30565 090e7dde4825560c6f7d5b37e1f633be 334 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 6 28 4.3E-5 T 16-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Spa2297_RS30565 090e7dde4825560c6f7d5b37e1f633be 334 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 34 2.3E-4 T 16-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Spa2297_RS30565 090e7dde4825560c6f7d5b37e1f633be 334 Gene3D G3DSA:2.115.10.20 156 323 5.0E-8 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS30565 090e7dde4825560c6f7d5b37e1f633be 334 Gene3D G3DSA:2.115.10.20 81 152 1.9E-6 T 16-09-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain Spa2297_RS04245 bec5a0d002025f50be7190304987d97a 252 Pfam PF09844 Uncharacterized conserved protein (COG2071) 21 234 5.2E-67 T 16-09-2016 IPR018644 Protein of unknown function DUF2071 Spa2297_RS04245 bec5a0d002025f50be7190304987d97a 252 SUPERFAMILY SSF160104 17 176 4.18E-15 T 16-09-2016 Spa2297_RS04245 bec5a0d002025f50be7190304987d97a 252 PANTHER PTHR39186 1 245 1.8E-82 T 16-09-2016 Spa2297_RS04245 bec5a0d002025f50be7190304987d97a 252 PANTHER PTHR39186:SF1 1 245 1.8E-82 T 16-09-2016 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 SUPERFAMILY SSF51905 489 545 2.96E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 SUPERFAMILY SSF51905 6 168 2.96E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 SUPERFAMILY SSF51905 198 315 2.96E-45 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 PANTHER PTHR10668 442 569 1.8E-265 T 16-09-2016 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 PANTHER PTHR10668 7 401 1.8E-265 T 16-09-2016 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Gene3D G3DSA:3.50.50.60 480 547 1.1E-84 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Gene3D G3DSA:3.50.50.60 206 311 1.1E-84 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Gene3D G3DSA:3.50.50.60 446 447 1.1E-84 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Gene3D G3DSA:3.50.50.60 6 128 1.1E-84 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 PANTHER PTHR10668:SF68 442 569 1.8E-265 T 16-09-2016 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 PANTHER PTHR10668:SF68 7 401 1.8E-265 T 16-09-2016 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Pfam PF00732 GMC oxidoreductase 8 288 6.3E-10 T 16-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Spa2297_RS20170 c171a6a819160ffa01def9e4f680510f 596 Pfam PF05199 GMC oxidoreductase 484 541 3.9E-13 T 16-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Spa2297_RS03800 71e52223d982b09969e94aac69aeccb9 263 Gene3D G3DSA:3.20.20.370 46 239 5.4E-42 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS03800 71e52223d982b09969e94aac69aeccb9 263 SUPERFAMILY SSF88713 43 239 2.09E-47 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS03800 71e52223d982b09969e94aac69aeccb9 263 Pfam PF01522 Polysaccharide deacetylase 48 165 3.3E-25 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS03800 71e52223d982b09969e94aac69aeccb9 263 PANTHER PTHR10587 46 240 1.8E-44 T 16-09-2016 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SUPERFAMILY SSF158472 194 243 3.79E-6 T 16-09-2016 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SMART SM00387 360 466 1.4E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SUPERFAMILY SSF47384 230 319 3.92E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SMART SM00304 191 246 1.6E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 PANTHER PTHR24423 185 475 3.3E-63 T 16-09-2016 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 Pfam PF00672 HAMP domain 172 241 2.7E-15 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SUPERFAMILY SSF55874 308 467 1.44E-35 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 Gene3D G3DSA:1.10.287.130 238 314 7.1E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 SMART SM00388 247 318 3.5E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 Gene3D G3DSA:3.30.565.10 329 470 2.2E-34 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 318 1.9E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 6.8E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 6.8E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 6.8E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 6.8E-13 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15410 ab4b74194f0cb9ae2db0be5f9b4dd847 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 463 1.8E-23 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 Gene3D G3DSA:3.40.190.10 179 349 1.7E-28 T 16-09-2016 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 Pfam PF01547 Bacterial extracellular solute-binding protein 76 359 8.8E-33 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 PANTHER PTHR30061:SF1 1 471 2.1E-87 T 16-09-2016 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 PANTHER PTHR30061 1 471 2.1E-87 T 16-09-2016 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 SUPERFAMILY SSF53850 27 468 1.49E-49 T 16-09-2016 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 Gene3D G3DSA:3.40.190.10 57 178 1.4E-20 T 16-09-2016 Spa2297_RS28675 d08ddcafbb19b93d759eb1713e0618bb 471 Gene3D G3DSA:3.40.190.10 350 376 1.4E-20 T 16-09-2016 Spa2297_RS21465 167730d8db0eb128868c939d09dcd226 166 Pfam PF04978 Protein of unknown function (DUF664) 25 162 2.8E-37 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS21465 167730d8db0eb128868c939d09dcd226 166 SUPERFAMILY SSF109854 11 161 7.48E-35 T 16-09-2016 Spa2297_RS21465 167730d8db0eb128868c939d09dcd226 166 Gene3D G3DSA:1.20.120.450 10 166 9.0E-40 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 PANTHER PTHR26402 1 223 2.2E-100 T 16-09-2016 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 SUPERFAMILY SSF46894 131 222 4.54E-28 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 Gene3D G3DSA:1.10.10.10 146 222 1.0E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 SMART SM00862 146 221 7.6E-30 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 Pfam PF00072 Response regulator receiver domain 1 109 6.0E-32 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 Gene3D G3DSA:3.40.50.2300 1 145 2.1E-46 T 16-09-2016 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 PANTHER PTHR26402:SF292 1 223 2.2E-100 T 16-09-2016 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 2.3E-27 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 SMART SM00448 1 109 2.1E-45 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS17145 9320ad6957bcd468e73de83d7da06953 229 SUPERFAMILY SSF52172 1 122 1.42E-44 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS01045 4971c3dbd802d824187b1b1c16c74191 401 PANTHER PTHR38165:SF2 3 401 6.3E-246 T 16-09-2016 Spa2297_RS01045 4971c3dbd802d824187b1b1c16c74191 401 Pfam PF16483 Beta-1,3-glucanase 41 397 3.9E-103 T 16-09-2016 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 Spa2297_RS01045 4971c3dbd802d824187b1b1c16c74191 401 PANTHER PTHR38165 3 401 6.3E-246 T 16-09-2016 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 PANTHER PTHR11712 15 445 1.2E-171 T 16-09-2016 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 257 2.8E-72 T 16-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 382 9.1E-38 T 16-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 Gene3D G3DSA:3.40.47.10 17 270 2.1E-78 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 SMART SM00825 Beta-ketoacyl synthase 17 436 1.4E-160 T 16-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 Gene3D G3DSA:3.40.47.10 271 433 6.1E-51 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 SUPERFAMILY SSF53901 12 126 8.81E-83 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 SUPERFAMILY SSF53901 153 379 8.81E-83 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS23945 ad1c4fd76e34f7317391de12720f6a13 476 PANTHER PTHR11712:SF285 15 445 1.2E-171 T 16-09-2016 Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 SUPERFAMILY SSF51735 9 166 1.65E-28 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 PANTHER PTHR21363:SF0 1 256 1.7E-59 T 16-09-2016 Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 SUPERFAMILY SSF48179 172 256 2.61E-21 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 PANTHER PTHR21363 1 256 1.7E-59 T 16-09-2016 Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 Gene3D G3DSA:3.40.50.720 4 176 6.6E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26605 bb60461c779d7e56e18a381568cd70ea 301 Pfam PF02153 Prephenate dehydrogenase 21 255 6.3E-56 T 16-09-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Spa2297_RS25630 077984de13b3ed9468ee7dd3e2ab5bbc 311 SUPERFAMILY SSF56112 16 265 4.9E-23 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS25630 077984de13b3ed9468ee7dd3e2ab5bbc 311 Gene3D G3DSA:3.90.1200.10 115 250 1.1E-12 T 16-09-2016 Spa2297_RS25630 077984de13b3ed9468ee7dd3e2ab5bbc 311 Pfam PF01636 Phosphotransferase enzyme family 28 252 9.6E-18 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS14645 be85079335bd55dde5dd92e06df97958 463 SUPERFAMILY SSF103473 90 444 3.27E-18 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14645 be85079335bd55dde5dd92e06df97958 463 Gene3D G3DSA:1.20.1250.20 91 236 1.1E-7 T 16-09-2016 Spa2297_RS14645 be85079335bd55dde5dd92e06df97958 463 Pfam PF07690 Major Facilitator Superfamily 88 415 2.4E-13 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01020 bad6cf337ebf79fc977cbe47dfe063d7 330 SUPERFAMILY SSF161098 113 313 1.57E-22 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01020 bad6cf337ebf79fc977cbe47dfe063d7 330 PANTHER PTHR30465:SF53 11 328 5.3E-195 T 16-09-2016 Spa2297_RS01020 bad6cf337ebf79fc977cbe47dfe063d7 330 Gene3D G3DSA:1.10.3720.10 114 322 1.8E-23 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01020 bad6cf337ebf79fc977cbe47dfe063d7 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 327 7.4E-42 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01020 bad6cf337ebf79fc977cbe47dfe063d7 330 PANTHER PTHR30465 11 328 5.3E-195 T 16-09-2016 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 SUPERFAMILY SSF69593 115 344 4.84E-33 T 16-09-2016 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 PANTHER PTHR22753:SF11 77 351 3.9E-156 T 16-09-2016 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 Gene3D G3DSA:3.40.1130.10 114 265 2.4E-5 T 16-09-2016 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 SMART SM00563 140 259 5.4E-17 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 PANTHER PTHR22753 77 351 3.9E-156 T 16-09-2016 Spa2297_RS18555 bf69b8542093fce97cd922e0646e8f15 353 Pfam PF01553 Acyltransferase 125 256 4.5E-16 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 PANTHER PTHR24423 161 431 6.9E-45 T 16-09-2016 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 SMART SM00387 330 433 1.2E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 430 7.2E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 PANTHER PTHR24423:SF477 161 431 6.9E-45 T 16-09-2016 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 SUPERFAMILY SSF47384 205 268 2.35E-7 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 Gene3D G3DSA:3.30.565.10 291 432 1.9E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 SUPERFAMILY SSF55874 292 429 5.63E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 Gene3D G3DSA:1.10.287.130 210 267 1.3E-6 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 270 2.6E-6 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 Pfam PF00672 HAMP domain 149 215 4.6E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS30840 042498a6f6321f0611ccd41417b9fe2a 440 SMART SM00304 167 219 7.0E-9 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 4.1E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 18 29 4.1E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 4.1E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 4.1E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 Gene3D G3DSA:3.40.50.1000 104 221 5.2E-42 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 Gene3D G3DSA:3.40.50.1000 13 32 5.2E-42 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PANTHER PTHR18901:SF21 18 201 1.2E-65 T 16-09-2016 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 199 1.4E-23 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 PANTHER PTHR18901 18 201 1.2E-65 T 16-09-2016 Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 SUPERFAMILY SSF56784 19 203 9.22E-46 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS06430 2bd8763f3cd1e315f400dc224fd54bd1 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 199 1.3E-15 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS06955 e222c272abe4c0046c68bfa83b4c13d0 345 SUPERFAMILY SSF101478 11 227 9.81E-60 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS06955 e222c272abe4c0046c68bfa83b4c13d0 345 SUPERFAMILY SSF101478 260 334 9.81E-60 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS06955 e222c272abe4c0046c68bfa83b4c13d0 345 PANTHER PTHR16222:SF12 11 334 3.9E-69 T 16-09-2016 Spa2297_RS06955 e222c272abe4c0046c68bfa83b4c13d0 345 PANTHER PTHR16222 11 334 3.9E-69 T 16-09-2016 Spa2297_RS06955 e222c272abe4c0046c68bfa83b4c13d0 345 Pfam PF03747 ADP-ribosylglycohydrolase 13 319 4.5E-56 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS31360 9ddc53050081757833e1cdc3013880e0 284 PANTHER PTHR10366 2 278 5.2E-41 T 16-09-2016 Spa2297_RS31360 9ddc53050081757833e1cdc3013880e0 284 SUPERFAMILY SSF51735 4 273 1.04E-45 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31360 9ddc53050081757833e1cdc3013880e0 284 Gene3D G3DSA:3.40.50.720 4 232 1.1E-38 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31360 9ddc53050081757833e1cdc3013880e0 284 Pfam PF13460 NAD(P)H-binding 7 155 1.1E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS30760 b61ca2da11700c52a3d9bf57bcabdc67 40 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 40 14.277 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30760 b61ca2da11700c52a3d9bf57bcabdc67 40 PANTHER PTHR18804 1 40 2.0E-13 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30760 b61ca2da11700c52a3d9bf57bcabdc67 40 Pfam PF00444 Ribosomal protein L36 1 40 1.9E-16 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS30760 b61ca2da11700c52a3d9bf57bcabdc67 40 PANTHER PTHR18804:SF11 1 40 2.0E-13 T 16-09-2016 Spa2297_RS30760 b61ca2da11700c52a3d9bf57bcabdc67 40 SUPERFAMILY SSF57840 1 40 2.35E-11 T 16-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 1.0E-13 T 16-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.656 T 16-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 16-09-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 Pfam PF00468 Ribosomal protein L34 3 45 5.1E-20 T 16-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 PANTHER PTHR14503 3 45 1.7E-15 T 16-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS16565 318bc78174e4f9439ec9dde509a0c5a0 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.1E-19 T 16-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spa2297_RS09275 49e6f58adfbb0e1ed1360665f6c8e5ce 293 Pfam PF10118 Predicted metal-dependent hydrolase 9 266 1.3E-78 T 16-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 Spa2297_RS09275 49e6f58adfbb0e1ed1360665f6c8e5ce 293 PANTHER PTHR39456:SF1 1 289 8.2E-196 T 16-09-2016 Spa2297_RS09275 49e6f58adfbb0e1ed1360665f6c8e5ce 293 PIRSF PIRSF007580 1 286 4.7E-125 T 16-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 Spa2297_RS09275 49e6f58adfbb0e1ed1360665f6c8e5ce 293 PANTHER PTHR39456 1 289 8.2E-196 T 16-09-2016 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 PANTHER PTHR10066:SF58 6 545 5.1E-271 T 16-09-2016 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 PANTHER PTHR10066:SF58 565 594 5.1E-271 T 16-09-2016 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Gene3D G3DSA:2.60.40.320 172 284 1.3E-15 T 16-09-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 SUPERFAMILY SSF49303 184 284 1.32E-9 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Gene3D G3DSA:2.60.120.260 7 171 3.4E-57 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 289 453 8.6E-6 T 16-09-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Pfam PF00703 Glycosyl hydrolases family 2 183 284 1.8E-5 T 16-09-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 PANTHER PTHR10066 6 545 5.1E-271 T 16-09-2016 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 PANTHER PTHR10066 565 594 5.1E-271 T 16-09-2016 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 24 145 6.3E-13 T 16-09-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 SUPERFAMILY SSF51445 288 594 7.25E-55 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 Gene3D G3DSA:3.20.20.80 286 594 1.4E-53 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS01215 5462ad9a01d34947fb0fe829f533ba03 608 SUPERFAMILY SSF49785 6 181 1.06E-48 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 PANTHER PTHR24220 4 323 2.8E-154 T 16-09-2016 Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 Pfam PF00005 ABC transporter 23 181 5.5E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 Gene3D G3DSA:3.40.50.300 2 255 8.4E-76 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 312 1.9E-27 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 SUPERFAMILY SSF52540 2 252 6.23E-70 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 SMART SM00382 31 231 2.4E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 3.9E-22 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21600 86a830d3ab0af30dff12d7333d6e64ca 327 PANTHER PTHR24220:SF535 4 323 2.8E-154 T 16-09-2016 Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 SMART SM01260 46 424 2.4E-13 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 SUPERFAMILY SSF158745 48 412 1.57E-29 T 16-09-2016 Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 PRINTS PR01950 LanC-like protein superfamily signature 95 113 9.1E-6 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 PRINTS PR01950 LanC-like protein superfamily signature 145 160 9.1E-6 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 PRINTS PR01950 LanC-like protein superfamily signature 275 295 9.1E-6 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 Pfam PF05147 Lanthionine synthetase C-like protein 49 228 6.2E-20 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS15120 2047202cf97611c489104796ff582b4b 434 Pfam PF05147 Lanthionine synthetase C-like protein 273 347 7.7E-11 T 16-09-2016 IPR007822 Lanthionine synthetase C-like Spa2297_RS12025 b62985706a02e600f7062e91dc5278ae 401 PANTHER PTHR41775 1 401 9.3E-129 T 16-09-2016 Spa2297_RS12025 b62985706a02e600f7062e91dc5278ae 401 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 55 330 7.1E-59 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS12025 b62985706a02e600f7062e91dc5278ae 401 Gene3D G3DSA:3.40.390.10 192 232 8.8E-5 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS18835 24d9baffcf4e3ef247d2b5dd34a26829 129 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 56 6.6E-11 T 16-09-2016 IPR027379 Cardiolipin synthase N-terminal Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 Gene3D G3DSA:1.10.3470.10 368 689 4.9E-87 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 Gene3D G3DSA:1.10.3470.10 22 349 3.3E-74 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 PANTHER PTHR30472 259 689 1.8E-170 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 SUPERFAMILY SSF81345 360 686 1.44E-72 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 Pfam PF01032 FecCD transport family 32 347 1.4E-68 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 Pfam PF01032 FecCD transport family 379 686 2.6E-82 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 SUPERFAMILY SSF81345 23 347 4.18E-56 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS01720 c86762634e50db0e471cca35014a62a0 689 PANTHER PTHR30472:SF16 259 689 1.8E-170 T 16-09-2016 Spa2297_RS03675 82763aad1e2575185b0da79a0ba57b6c 311 PANTHER PTHR34978 1 309 2.8E-49 T 16-09-2016 Spa2297_RS03675 82763aad1e2575185b0da79a0ba57b6c 311 Pfam PF01435 Peptidase family M48 140 215 3.1E-8 T 16-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spa2297_RS03675 82763aad1e2575185b0da79a0ba57b6c 311 Gene3D G3DSA:3.30.2010.10 134 196 2.3E-8 T 16-09-2016 Spa2297_RS16730 52136d3a6fc4ccb7542fdc2f7b2484a1 478 Pfam PF01098 Cell cycle protein 87 457 5.9E-81 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS16730 52136d3a6fc4ccb7542fdc2f7b2484a1 478 PANTHER PTHR30474:SF3 62 474 5.0E-225 T 16-09-2016 Spa2297_RS16730 52136d3a6fc4ccb7542fdc2f7b2484a1 478 PANTHER PTHR30474 62 474 5.0E-225 T 16-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 Spa2297_RS31015 64b4e01de52a97d85f73b27b83513b2a 367 Pfam PF01594 Domain of unknown function DUF20 25 345 2.1E-56 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS31015 64b4e01de52a97d85f73b27b83513b2a 367 PANTHER PTHR21716 25 362 4.1E-75 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 PANTHER PTHR10434:SF21 14 210 8.9E-50 T 16-09-2016 Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 Gene3D G3DSA:3.40.1130.10 24 208 1.1E-13 T 16-09-2016 Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 Pfam PF01553 Acyltransferase 30 148 2.6E-16 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 SUPERFAMILY SSF69593 19 207 2.88E-32 T 16-09-2016 Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 PANTHER PTHR10434 14 210 8.9E-50 T 16-09-2016 Spa2297_RS06930 525affc31b7101243855488d17a69aaf 215 SMART SM00563 41 151 2.7E-23 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS01940 37f2e5988d688e9faee49f42b21562c6 218 PANTHER PTHR30055:SF73 1 136 1.3E-26 T 16-09-2016 Spa2297_RS01940 37f2e5988d688e9faee49f42b21562c6 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 2.0E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01940 37f2e5988d688e9faee49f42b21562c6 218 PANTHER PTHR30055 1 136 1.3E-26 T 16-09-2016 Spa2297_RS01940 37f2e5988d688e9faee49f42b21562c6 218 Gene3D G3DSA:1.10.357.10 4 208 4.6E-28 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS01940 37f2e5988d688e9faee49f42b21562c6 218 SUPERFAMILY SSF46689 6 86 1.28E-13 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS12690 f4bdb729a1b0967af8cf98346ee5884f 209 Pfam PF14435 SUKH-4 immunity protein 73 198 6.6E-23 T 16-09-2016 IPR025851 SUKH-4 immunity protein Spa2297_RS28575 d3e7ed583aad1c9fdd4441aba8c1945c 359 SUPERFAMILY SSF55486 214 222 7.84E-24 T 16-09-2016 Spa2297_RS28575 d3e7ed583aad1c9fdd4441aba8c1945c 359 SUPERFAMILY SSF55486 22 176 7.84E-24 T 16-09-2016 Spa2297_RS28575 d3e7ed583aad1c9fdd4441aba8c1945c 359 Gene3D G3DSA:3.40.390.10 29 254 2.1E-22 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS11385 f0e40d2dc44ba721e5bfb19b9c7fecef 704 Pfam PF01926 50S ribosome-binding GTPase 227 348 6.5E-7 T 16-09-2016 IPR006073 GTP binding domain GO:0005525 Spa2297_RS11385 f0e40d2dc44ba721e5bfb19b9c7fecef 704 Gene3D G3DSA:3.40.50.300 213 424 3.7E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11385 f0e40d2dc44ba721e5bfb19b9c7fecef 704 SUPERFAMILY SSF52540 218 426 6.24E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24340 1ea26ce1fe1e3ef511d341e416214ece 181 Pfam PF02464 Competence-damaged protein 3 159 7.0E-48 T 16-09-2016 IPR008136 CinA, C-terminal Spa2297_RS24340 1ea26ce1fe1e3ef511d341e416214ece 181 Gene3D G3DSA:3.90.950.20 3 163 3.2E-55 T 16-09-2016 IPR008136 CinA, C-terminal Spa2297_RS24340 1ea26ce1fe1e3ef511d341e416214ece 181 SUPERFAMILY SSF142433 3 162 7.59E-45 T 16-09-2016 IPR008136 CinA, C-terminal Spa2297_RS24340 1ea26ce1fe1e3ef511d341e416214ece 181 PANTHER PTHR13939 5 170 4.9E-63 T 16-09-2016 Spa2297_RS24340 1ea26ce1fe1e3ef511d341e416214ece 181 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 159 9.3E-36 T 16-09-2016 IPR008136 CinA, C-terminal Spa2297_RS31105 3ea053943a55c548348731f4211afc18 572 Pfam PF12708 Pectate lyase superfamily protein 95 180 1.8E-15 T 16-09-2016 IPR024535 Pectate lyase superfamily protein Spa2297_RS31105 3ea053943a55c548348731f4211afc18 572 SUPERFAMILY SSF51126 351 503 1.5E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS31105 3ea053943a55c548348731f4211afc18 572 SUPERFAMILY SSF51126 90 238 1.5E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS31105 3ea053943a55c548348731f4211afc18 572 Gene3D G3DSA:2.160.20.10 353 516 7.1E-38 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS31105 3ea053943a55c548348731f4211afc18 572 Gene3D G3DSA:2.160.20.10 87 215 7.1E-38 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS00240 b0b8a98f66ffb86ad4890f58a22aebb9 137 SUPERFAMILY SSF55874 42 132 1.54E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00240 b0b8a98f66ffb86ad4890f58a22aebb9 137 Pfam PF13581 Histidine kinase-like ATPase domain 19 127 4.2E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS10020 987353aacc787b5f9fc6a313d467191f 271 SUPERFAMILY SSF56601 8 267 1.47E-55 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS10020 987353aacc787b5f9fc6a313d467191f 271 Gene3D G3DSA:3.40.710.10 9 268 7.8E-49 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS10020 987353aacc787b5f9fc6a313d467191f 271 PANTHER PTHR22935:SF57 1 256 8.4E-153 T 16-09-2016 Spa2297_RS10020 987353aacc787b5f9fc6a313d467191f 271 Pfam PF00144 Beta-lactamase 15 263 1.9E-38 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS10020 987353aacc787b5f9fc6a313d467191f 271 PANTHER PTHR22935 1 256 8.4E-153 T 16-09-2016 Spa2297_RS06500 ff2b0dd00cafbdccfdbba81ac59a34f8 328 PANTHER PTHR11732 1 326 8.3E-149 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS06500 ff2b0dd00cafbdccfdbba81ac59a34f8 328 SUPERFAMILY SSF51430 1 317 2.36E-87 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS06500 ff2b0dd00cafbdccfdbba81ac59a34f8 328 Pfam PF00248 Aldo/keto reductase family 15 313 1.5E-58 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS06500 ff2b0dd00cafbdccfdbba81ac59a34f8 328 PANTHER PTHR11732:SF191 1 326 8.3E-149 T 16-09-2016 Spa2297_RS06500 ff2b0dd00cafbdccfdbba81ac59a34f8 328 Gene3D G3DSA:3.20.20.100 9 322 7.5E-88 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 Pfam PF12697 Alpha/beta hydrolase family 126 388 1.4E-23 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992 29 98 5.5E-109 T 16-09-2016 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992 117 266 5.5E-109 T 16-09-2016 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992 290 396 5.5E-109 T 16-09-2016 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 SUPERFAMILY SSF53474 115 395 7.03E-49 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 Gene3D G3DSA:3.40.50.1820 102 396 1.5E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992:SF859 290 396 5.5E-109 T 16-09-2016 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992:SF859 29 98 5.5E-109 T 16-09-2016 Spa2297_RS20010 41feeefda283423f7731b3d0e7b0ba84 419 PANTHER PTHR10992:SF859 117 266 5.5E-109 T 16-09-2016 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 Pfam PF13560 Helix-turn-helix domain 12 92 2.5E-17 T 16-09-2016 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 Gene3D G3DSA:1.10.260.40 7 88 1.3E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 SMART SM00530 16 89 3.9E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 PANTHER PTHR35010:SF2 1 294 3.5E-86 T 16-09-2016 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 PANTHER PTHR35010 1 294 3.5E-86 T 16-09-2016 Spa2297_RS01850 32363f932cacd55a877cc8790e9ef651 304 SUPERFAMILY SSF47413 37 86 1.21E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 Gene3D G3DSA:3.90.25.10 180 315 2.3E-48 T 16-09-2016 Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 4.9E-74 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 PANTHER PTHR10366 2 316 8.8E-142 T 16-09-2016 Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 SUPERFAMILY SSF51735 1 316 5.43E-97 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 316 3.6E-121 T 16-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 PANTHER PTHR10366:SF41 2 316 8.8E-142 T 16-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 Gene3D G3DSA:3.40.50.720 1 179 8.7E-64 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29965 caabcff97ec47bd307ee66ee458ebb82 318 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 SMART SM00563 35 154 3.2E-38 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 PANTHER PTHR10434 1 233 2.2E-93 T 16-09-2016 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 SUPERFAMILY SSF69593 2 217 2.75E-53 T 16-09-2016 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 Gene3D G3DSA:3.40.1130.10 3 206 6.1E-32 T 16-09-2016 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 PANTHER PTHR10434:SF21 1 233 2.2E-93 T 16-09-2016 Spa2297_RS04445 4eabd5185d3ce06c00938c51ed7e0df7 240 Pfam PF01553 Acyltransferase 21 151 1.3E-22 T 16-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 PANTHER PTHR31683:SF12 41 104 4.4E-144 T 16-09-2016 Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 PANTHER PTHR31683 41 104 4.4E-144 T 16-09-2016 Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 SUPERFAMILY SSF51126 151 442 3.88E-67 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 SUPERFAMILY SSF51126 49 115 3.88E-67 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 Gene3D G3DSA:2.160.20.10 43 442 1.3E-103 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 PANTHER PTHR31683 157 379 4.4E-144 T 16-09-2016 Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 PANTHER PTHR31683:SF12 157 379 4.4E-144 T 16-09-2016 Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 Pfam PF00544 Pectate lyase 149 362 4.2E-49 T 16-09-2016 IPR002022 Pectate lyase/Amb allergen Spa2297_RS07500 0e7112839a1329c7fa5199e461b4d26f 443 SMART SM00656 137 368 8.0E-39 T 16-09-2016 IPR002022 Pectate lyase/Amb allergen Spa2297_RS32830 a72a90930916a906703f16d0049ce92a 330 Gene3D G3DSA:3.20.20.100 151 326 7.4E-44 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32830 a72a90930916a906703f16d0049ce92a 330 PANTHER PTHR11732:SF191 152 330 1.4E-113 T 16-09-2016 Spa2297_RS32830 a72a90930916a906703f16d0049ce92a 330 Pfam PF00248 Aldo/keto reductase family 167 318 4.9E-32 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32830 a72a90930916a906703f16d0049ce92a 330 SUPERFAMILY SSF51430 152 326 1.23E-48 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS32830 a72a90930916a906703f16d0049ce92a 330 PANTHER PTHR11732 152 330 1.4E-113 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 PANTHER PTHR30388 171 375 1.4E-143 T 16-09-2016 Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 PANTHER PTHR30388 1 124 1.4E-143 T 16-09-2016 Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 Pfam PF13478 XdhC Rossmann domain 206 348 1.6E-41 T 16-09-2016 IPR027051 XdhC Rossmann domain Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 PANTHER PTHR30388:SF4 1 124 1.4E-143 T 16-09-2016 Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 Pfam PF02625 XdhC and CoxI family 11 78 5.4E-21 T 16-09-2016 IPR003777 XdhC- CoxI Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 Pfam PF02625 XdhC and CoxI family 119 180 3.4E-12 T 16-09-2016 IPR003777 XdhC- CoxI Spa2297_RS03805 e498160dc91eda7c13cd0625f3230626 376 PANTHER PTHR30388:SF4 171 375 1.4E-143 T 16-09-2016 Spa2297_RS27090 7cfa160cd43e23ab603238316768aca0 108 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 19 33 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS27090 7cfa160cd43e23ab603238316768aca0 108 PANTHER PTHR35344:SF1 5 108 5.8E-49 T 16-09-2016 Spa2297_RS27090 7cfa160cd43e23ab603238316768aca0 108 Pfam PF00741 Gas vesicle protein 18 56 3.5E-17 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS27090 7cfa160cd43e23ab603238316768aca0 108 PANTHER PTHR35344 5 108 5.8E-49 T 16-09-2016 Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 Gene3D G3DSA:3.40.50.1820 4 486 5.1E-125 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 178 193 - T 16-09-2016 IPR019826 Carboxylesterase type B, active site Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 PANTHER PTHR11559 1 484 4.5E-136 T 16-09-2016 Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 SUPERFAMILY SSF53474 8 486 5.76E-108 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 PANTHER PTHR11559:SF142 1 484 4.5E-136 T 16-09-2016 Spa2297_RS25890 4c390f1b40bed9c6c54583496209b956 501 Pfam PF00135 Carboxylesterase family 7 459 2.7E-91 T 16-09-2016 IPR002018 Carboxylesterase, type B Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 297 4.4E-94 T 16-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 Gene3D G3DSA:3.40.1190.20 34 297 9.7E-79 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 SUPERFAMILY SSF53613 2 283 3.74E-63 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 PANTHER PTHR10584:SF170 2 296 2.1E-100 T 16-09-2016 Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 Pfam PF00294 pfkB family carbohydrate kinase 14 285 4.1E-44 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 PANTHER PTHR10584 2 296 2.1E-100 T 16-09-2016 Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS14860 41cb44234eb16694ec2a676577a47f7e 310 PIRSF PIRSF000535 1 305 2.5E-82 T 16-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spa2297_RS26450 3683c5b33c92942c46e06d03a5106ccb 131 SUPERFAMILY SSF53933 38 129 1.6E-36 T 16-09-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 Spa2297_RS26450 3683c5b33c92942c46e06d03a5106ccb 131 Pfam PF00545 ribonuclease 46 124 1.6E-28 T 16-09-2016 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 Spa2297_RS26450 3683c5b33c92942c46e06d03a5106ccb 131 Gene3D G3DSA:3.10.450.30 38 128 4.7E-40 T 16-09-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 181 4.8E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 122 138 4.8E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.8E-5 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 48 179 1.7E-14 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 81 173 2.3E-11 T 16-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 Gene3D G3DSA:3.40.50.1000 1 210 3.6E-32 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 SUPERFAMILY SSF56784 1 193 1.22E-36 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12270 c24b38372938cba9bffa4139012cc5c8 220 PANTHER PTHR12725 1 217 7.4E-25 T 16-09-2016 Spa2297_RS06415 351ee5af0ac7b07efa7185d19479227d 329 Pfam PF12705 PD-(D/E)XK nuclease superfamily 52 300 1.4E-37 T 16-09-2016 Spa2297_RS06415 351ee5af0ac7b07efa7185d19479227d 329 SUPERFAMILY SSF52980 78 243 1.82E-10 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 Pfam PF01063 Amino-transferase class IV 74 316 6.2E-30 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 267 - T 16-09-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 360 1.8E-132 T 16-09-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 PIRSF PIRSF006468 5 362 3.0E-133 T 16-09-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 SUPERFAMILY SSF56752 12 359 3.79E-118 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 PANTHER PTHR11825 14 360 6.0E-152 T 16-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 Gene3D G3DSA:3.30.470.10 21 179 3.0E-73 T 16-09-2016 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 Gene3D G3DSA:3.20.10.10 180 348 2.0E-66 T 16-09-2016 Spa2297_RS23380 5b4a826969189df901c75feeb97c8d69 362 PANTHER PTHR11825:SF2 14 360 6.0E-152 T 16-09-2016 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785:SF415 489 508 5.0E-75 T 16-09-2016 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785:SF415 392 421 5.0E-75 T 16-09-2016 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785:SF415 71 372 5.0E-75 T 16-09-2016 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785 71 372 5.0E-75 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 Pfam PF00324 Amino acid permease 44 377 3.5E-10 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785 489 508 5.0E-75 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PANTHER PTHR11785 392 421 5.0E-75 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS06570 d601c3d0ba11c4e7ccdc2972390bf9cf 512 PIRSF PIRSF006060 8 449 2.3E-46 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 PANTHER PTHR11717:SF14 32 129 1.8E-15 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 PANTHER PTHR11717 155 220 1.8E-15 T 16-09-2016 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 PANTHER PTHR11717:SF14 155 220 1.8E-15 T 16-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 33 153 5.5E-15 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 PANTHER PTHR11717 32 129 1.8E-15 T 16-09-2016 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 Gene3D G3DSA:3.40.50.270 182 219 1.8E-31 T 16-09-2016 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 Gene3D G3DSA:3.40.50.270 31 143 1.8E-31 T 16-09-2016 Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 SMART SM00226 31 218 4.2E-7 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 SUPERFAMILY SSF52788 189 217 2.75E-23 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS22650 1fb4a0378bb04e6f2cf7e9ad29aa2d54 226 SUPERFAMILY SSF52788 30 152 2.75E-23 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 55 337 41.643 T 16-09-2016 IPR005337 RapZ-like family GO:0005524 Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 PANTHER PTHR30448:SF0 46 338 1.4E-160 T 16-09-2016 Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 Pfam PF03668 P-loop ATPase protein family 56 338 3.3E-111 T 16-09-2016 IPR005337 RapZ-like family GO:0005524 Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 PANTHER PTHR30448 46 338 1.4E-160 T 16-09-2016 Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 SUPERFAMILY SSF52540 56 208 4.17E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 Gene3D G3DSA:3.40.50.300 50 209 2.4E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07870 23ac18abe172ee87509c17dec7635b15 338 PIRSF PIRSF005052 55 338 1.6E-111 T 16-09-2016 IPR005337 RapZ-like family GO:0005524 Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 PIRSF PIRSF036551 2 280 9.0E-114 T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 Gene3D G3DSA:1.20.141.10 154 280 2.2E-65 T 16-09-2016 Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 Pfam PF01374 Glycosyl hydrolase family 46 59 268 1.9E-99 T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 Gene3D G3DSA:3.30.386.10 40 153 7.8E-58 T 16-09-2016 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 SUPERFAMILY SSF53955 46 279 3.94E-93 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS30305 abd1f0062573d03f73240f6c2145a32a 280 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 65 103 - T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Gene3D G3DSA:1.10.10.10 944 1013 4.7E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 984 996 2.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 954 968 2.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 968 984 2.2E-12 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 PANTHER PTHR16305 883 980 2.1E-71 T 16-09-2016 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 PANTHER PTHR16305 10 456 2.1E-71 T 16-09-2016 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Gene3D G3DSA:1.25.40.10 555 812 2.2E-19 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Gene3D G3DSA:1.25.40.10 864 931 2.2E-19 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SUPERFAMILY SSF46894 946 1014 3.74E-20 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Gene3D G3DSA:3.40.50.300 14 74 2.3E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Gene3D G3DSA:3.40.50.300 131 207 2.3E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SUPERFAMILY SSF48452 557 743 1.56E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SMART SM00421 951 1008 4.1E-26 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Pfam PF00196 Bacterial regulatory proteins, luxR family 954 1008 5.1E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 Pfam PF13191 AAA ATPase domain 14 187 1.7E-31 T 16-09-2016 Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SUPERFAMILY SSF52540 14 76 4.25E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SUPERFAMILY SSF52540 126 260 4.25E-12 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23300 8316d5b1a38490deaa7eaf83f449ebfb 1025 SMART SM00382 35 222 0.0096 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 SUPERFAMILY SSF55103 281 531 8.18E-43 T 16-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 Gene3D G3DSA:3.30.465.10 159 277 2.7E-25 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 SUPERFAMILY SSF56176 40 277 3.36E-50 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 Gene3D G3DSA:3.30.43.10 52 158 1.1E-15 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 PANTHER PTHR11748:SF3 26 530 1.9E-161 T 16-09-2016 IPR025650 Alkyldihydroxyacetonephosphate synthase GO:0008609|GO:0008610 KEGG: 00565+2.5.1.26|UniPathway: UPA00781 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 Pfam PF01565 FAD binding domain 101 240 1.5E-34 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 PANTHER PTHR11748 26 530 1.9E-161 T 16-09-2016 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 Pfam PF02913 FAD linked oxidases, C-terminal domain 277 526 8.4E-51 T 16-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Spa2297_RS30345 54d2ec02ef947d2cbd39fe022b5ccc6b 532 Gene3D G3DSA:1.10.45.10 489 526 1.2E-7 T 16-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Spa2297_RS16190 2b307d0b3077b404784591eb854a6059 216 SUPERFAMILY SSF52833 54 212 9.92E-35 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS16190 2b307d0b3077b404784591eb854a6059 216 Gene3D G3DSA:3.40.30.10 11 213 1.1E-42 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS16190 2b307d0b3077b404784591eb854a6059 216 Pfam PF02630 SCO1/SenC 49 158 2.7E-25 T 16-09-2016 IPR003782 Copper chaperone SCO1/SenC Spa2297_RS16190 2b307d0b3077b404784591eb854a6059 216 PANTHER PTHR12151:SF0 2 212 4.9E-58 T 16-09-2016 Spa2297_RS16190 2b307d0b3077b404784591eb854a6059 216 PANTHER PTHR12151 2 212 4.9E-58 T 16-09-2016 IPR003782 Copper chaperone SCO1/SenC Spa2297_RS31110 671d6ff840c9a99cd89648644d9f3419 363 PANTHER PTHR36845:SF1 23 347 4.6E-68 T 16-09-2016 Spa2297_RS31110 671d6ff840c9a99cd89648644d9f3419 363 SUPERFAMILY SSF48208 19 350 7.48E-102 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS31110 671d6ff840c9a99cd89648644d9f3419 363 Gene3D G3DSA:1.50.10.10 12 349 6.5E-121 T 16-09-2016 IPR012341 Six-hairpin glycosidase GO:0003824 Spa2297_RS31110 671d6ff840c9a99cd89648644d9f3419 363 Pfam PF07470 Glycosyl Hydrolase Family 88 30 322 6.7E-24 T 16-09-2016 IPR010905 Glycosyl hydrolase, family 88 Spa2297_RS31110 671d6ff840c9a99cd89648644d9f3419 363 PANTHER PTHR36845 23 347 4.6E-68 T 16-09-2016 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 SMART SM00191 426 476 19.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 SMART SM00191 35 93 26.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 SMART SM00191 356 414 1.7E-7 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 SMART SM00191 105 166 0.26 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 Gene3D G3DSA:2.130.10.130 241 370 6.1E-15 T 16-09-2016 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 Gene3D G3DSA:2.130.10.130 371 498 4.4E-18 T 16-09-2016 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 Gene3D G3DSA:2.130.10.130 46 178 6.9E-19 T 16-09-2016 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 Pfam PF01839 FG-GAP repeat 361 398 6.4E-9 T 16-09-2016 IPR013517 FG-GAP repeat Reactome: REACT_13552 Spa2297_RS00320 423f58f08b4ab65e881d56e0dd705fd9 499 SUPERFAMILY SSF69318 34 455 5.95E-49 T 16-09-2016 Spa2297_RS31920 1915ad5607f4f046bdea423c79b65868 317 SUPERFAMILY SSF51004 9 308 4.19E-37 T 16-09-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain Spa2297_RS31920 1915ad5607f4f046bdea423c79b65868 317 Gene3D G3DSA:2.130.10.10 242 315 5.0E-4 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS31920 1915ad5607f4f046bdea423c79b65868 317 Gene3D G3DSA:2.130.10.10 6 241 1.3E-17 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS15675 2040ae419c351d5f6654f2c8dcc7d968 259 PANTHER PTHR10204 1 237 9.9E-98 T 16-09-2016 Spa2297_RS15675 2040ae419c351d5f6654f2c8dcc7d968 259 Gene3D G3DSA:3.40.50.360 2 233 3.4E-72 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS15675 2040ae419c351d5f6654f2c8dcc7d968 259 SUPERFAMILY SSF52218 2 238 6.92E-70 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS15675 2040ae419c351d5f6654f2c8dcc7d968 259 PANTHER PTHR10204:SF46 1 237 9.9E-98 T 16-09-2016 Spa2297_RS15675 2040ae419c351d5f6654f2c8dcc7d968 259 Pfam PF02525 Flavodoxin-like fold 2 214 4.7E-57 T 16-09-2016 IPR003680 Flavodoxin-like fold Spa2297_RS04240 851f3cc15382a1be630d4b2a8e5300e6 130 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 7 128 2.7E-36 T 16-09-2016 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 Spa2297_RS04240 851f3cc15382a1be630d4b2a8e5300e6 130 SUPERFAMILY SSF54427 7 125 2.56E-31 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS04240 851f3cc15382a1be630d4b2a8e5300e6 130 Gene3D G3DSA:3.10.450.50 2 128 3.8E-37 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS04240 851f3cc15382a1be630d4b2a8e5300e6 130 Pfam PF14534 Domain of unknown function (DUF4440) 11 118 2.6E-14 T 16-09-2016 IPR027843 Domain of unknown function DUF4440 Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 Pfam PF00571 CBS domain 281 330 2.9E-6 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 Pfam PF00571 CBS domain 220 267 2.8E-5 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 SUPERFAMILY SSF54631 203 340 2.02E-24 T 16-09-2016 Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 Gene3D G3DSA:3.10.580.10 220 330 5.0E-17 T 16-09-2016 Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 PANTHER PTHR22777 3 335 2.5E-122 T 16-09-2016 Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 SMART SM00116 282 330 0.028 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 SMART SM00116 222 270 0.021 T 16-09-2016 IPR000644 CBS domain Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 Pfam PF01595 Domain of unknown function DUF21 8 198 4.1E-38 T 16-09-2016 IPR002550 Domain of unknown function DUF21 Spa2297_RS05395 e772d61ca92a27ce6909372e976ca7ce 371 PANTHER PTHR22777:SF18 3 335 2.5E-122 T 16-09-2016 Spa2297_RS25955 b81f30032323271d4744659809c6e1d8 391 SUPERFAMILY SSF55874 299 386 8.08E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25955 b81f30032323271d4744659809c6e1d8 391 Pfam PF07730 Histidine kinase 187 251 2.5E-16 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS25955 b81f30032323271d4744659809c6e1d8 391 Gene3D G3DSA:3.30.565.10 302 387 3.7E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25955 b81f30032323271d4744659809c6e1d8 391 PANTHER PTHR24421:SF26 54 391 4.3E-84 T 16-09-2016 Spa2297_RS25955 b81f30032323271d4744659809c6e1d8 391 PANTHER PTHR24421 54 391 4.3E-84 T 16-09-2016 Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 SMART SM00226 7 132 3.6E-50 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 PANTHER PTHR11717:SF18 1 134 1.5E-41 T 16-09-2016 Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 Gene3D G3DSA:3.40.50.270 6 131 6.0E-42 T 16-09-2016 Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 129 4.8E-25 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 SUPERFAMILY SSF52788 6 131 1.44E-38 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS04040 ffd121c3f8f3a4b931bcbb68fbcb5ff5 138 PANTHER PTHR11717 1 134 1.5E-41 T 16-09-2016 Spa2297_RS20580 a66c87d68c7dba7e7855f304a22ac8c7 217 PIRSF PIRSF006324 1 217 1.2E-52 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS20580 a66c87d68c7dba7e7855f304a22ac8c7 217 PANTHER PTHR30086:SF15 2 214 8.3E-80 T 16-09-2016 Spa2297_RS20580 a66c87d68c7dba7e7855f304a22ac8c7 217 Pfam PF01810 LysE type translocator 17 214 4.4E-44 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS20580 a66c87d68c7dba7e7855f304a22ac8c7 217 PANTHER PTHR30086 2 214 8.3E-80 T 16-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 Gene3D G3DSA:3.30.428.10 4 117 1.4E-35 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 PANTHER PTHR23089 1 117 3.4E-49 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 SUPERFAMILY SSF54197 6 116 2.17E-32 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 PANTHER PTHR23089:SF2 1 117 3.4E-49 T 16-09-2016 Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 Pfam PF01230 HIT domain 17 110 2.1E-23 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 PRINTS PR00332 Histidine triad family signature 97 107 5.0E-18 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 PRINTS PR00332 Histidine triad family signature 10 26 5.0E-18 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS10730 2108b1aa10cb5df67233ae1cf5d9a1f5 117 PRINTS PR00332 Histidine triad family signature 31 49 5.0E-18 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS11825 5c6b5ddeb980e7d4ce0f0394c876eb28 175 Gene3D G3DSA:3.40.50.620 41 175 2.0E-31 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS11825 5c6b5ddeb980e7d4ce0f0394c876eb28 175 SUPERFAMILY SSF52402 42 175 2.26E-21 T 16-09-2016 Spa2297_RS11825 5c6b5ddeb980e7d4ce0f0394c876eb28 175 Pfam PF00582 Universal stress protein family 42 175 8.0E-22 T 16-09-2016 IPR006016 UspA GO:0006950 Spa2297_RS11825 5c6b5ddeb980e7d4ce0f0394c876eb28 175 PRINTS PR01438 Universal stress protein signature 153 175 1.9E-6 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS11825 5c6b5ddeb980e7d4ce0f0394c876eb28 175 PRINTS PR01438 Universal stress protein signature 39 57 1.9E-6 T 16-09-2016 IPR006015 Universal stress protein A Spa2297_RS11625 4ddfa7f765eea3a45f4c02c90fe8dd2a 294 SUPERFAMILY SSF51658 8 282 6.68E-60 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS11625 4ddfa7f765eea3a45f4c02c90fe8dd2a 294 PANTHER PTHR12110 4 276 6.1E-126 T 16-09-2016 Spa2297_RS11625 4ddfa7f765eea3a45f4c02c90fe8dd2a 294 PANTHER PTHR12110:SF27 4 276 6.1E-126 T 16-09-2016 Spa2297_RS11625 4ddfa7f765eea3a45f4c02c90fe8dd2a 294 Gene3D G3DSA:3.20.20.150 14 279 2.2E-72 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS11625 4ddfa7f765eea3a45f4c02c90fe8dd2a 294 Pfam PF01261 Xylose isomerase-like TIM barrel 29 230 3.3E-32 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS01410 a1fcb6ab478bbbf19823ac04a1834f88 197 PANTHER PTHR11711:SF117 22 192 2.1E-49 T 16-09-2016 Spa2297_RS01410 a1fcb6ab478bbbf19823ac04a1834f88 197 Pfam PF03029 Conserved hypothetical ATP binding protein 26 193 1.2E-22 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS01410 a1fcb6ab478bbbf19823ac04a1834f88 197 Gene3D G3DSA:3.40.50.300 18 194 6.4E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01410 a1fcb6ab478bbbf19823ac04a1834f88 197 PANTHER PTHR11711 22 192 2.1E-49 T 16-09-2016 Spa2297_RS01410 a1fcb6ab478bbbf19823ac04a1834f88 197 SUPERFAMILY SSF52540 20 195 3.36E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27595 72eb74c4591e3b0fe13588a83c1e651d 444 Pfam PF09471 IgA Peptidase M64 83 338 3.7E-78 T 16-09-2016 IPR019026 Peptidase M64, IgA Spa2297_RS27595 72eb74c4591e3b0fe13588a83c1e651d 444 Gene3D G3DSA:3.40.390.10 225 250 1.2E-4 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS27595 72eb74c4591e3b0fe13588a83c1e651d 444 Gene3D G3DSA:3.40.390.10 85 185 1.2E-4 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.141 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 5.5E-19 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 5.5E-19 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 5.5E-19 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 5.5E-19 T 16-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 Gene3D G3DSA:3.90.230.10 4 255 4.6E-74 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 SUPERFAMILY SSF55920 4 253 7.33E-71 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PANTHER PTHR10804 1 253 8.5E-92 T 16-09-2016 Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 Pfam PF00557 Metallopeptidase family M24 11 246 4.7E-45 T 16-09-2016 IPR000994 Peptidase M24, structural domain Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 PANTHER PTHR10804:SF41 1 253 8.5E-92 T 16-09-2016 Spa2297_RS26735 e200a14b0ee5949fb4f1500eadef86ce 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 254 1.1E-76 T 16-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 Spa2297_RS29335 5396610c03959171bc14614eb8c84682 357 SUPERFAMILY SSF51395 1 356 6.28E-107 T 16-09-2016 Spa2297_RS29335 5396610c03959171bc14614eb8c84682 357 PANTHER PTHR22893:SF14 5 357 5.1E-139 T 16-09-2016 Spa2297_RS29335 5396610c03959171bc14614eb8c84682 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 332 2.2E-73 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS29335 5396610c03959171bc14614eb8c84682 357 Gene3D G3DSA:3.20.20.70 3 356 5.8E-115 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS29335 5396610c03959171bc14614eb8c84682 357 PANTHER PTHR22893 5 357 5.1E-139 T 16-09-2016 Spa2297_RS00515 b4724ba2d3f192c07480c12bf03484ea 454 PANTHER PTHR11785 16 443 5.9E-77 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS00515 b4724ba2d3f192c07480c12bf03484ea 454 Pfam PF13520 Amino acid permease 29 411 6.5E-42 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS00515 b4724ba2d3f192c07480c12bf03484ea 454 PIRSF PIRSF006060 2 451 1.8E-78 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS19145 153957a07163009601ca1375c1adbe9d 973 SMART SM01043 816 962 7.4E-4 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS19145 153957a07163009601ca1375c1adbe9d 973 Pfam PF03704 Bacterial transcriptional activator domain 817 930 6.5E-7 T 16-09-2016 IPR005158 Bacterial transcriptional activator domain Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 Gene3D G3DSA:3.40.50.2300 103 214 2.7E-32 T 16-09-2016 Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 PANTHER PTHR32196:SF9 103 361 8.5E-51 T 16-09-2016 Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 PANTHER PTHR32196 103 361 8.5E-51 T 16-09-2016 Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 Pfam PF13407 Periplasmic binding protein domain 103 352 7.0E-51 T 16-09-2016 IPR025997 Periplasmic binding protein Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 Gene3D G3DSA:3.40.50.2300 215 372 3.6E-44 T 16-09-2016 Spa2297_RS32415 af6a0900d62b301dc242ec9950a3e3d6 374 SUPERFAMILY SSF53822 90 372 2.2E-72 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 Pfam PF02342 TerD domain 64 162 2.9E-18 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 PANTHER PTHR32097:SF4 441 578 5.3E-136 T 16-09-2016 Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 PANTHER PTHR32097 441 578 5.3E-136 T 16-09-2016 Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 PANTHER PTHR32097:SF4 1 338 5.3E-136 T 16-09-2016 Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 PANTHER PTHR32097 1 338 5.3E-136 T 16-09-2016 Spa2297_RS07930 caeff106722f804d69a9d275aa5e7283 679 Gene3D G3DSA:2.60.60.30 65 162 2.4E-17 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Gene3D G3DSA:2.40.10.10 199 337 2.2E-29 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 SUPERFAMILY SSF50494 80 335 5.05E-53 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 138 143 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Gene3D G3DSA:2.115.10.10 402 502 1.3E-6 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Gene3D G3DSA:2.115.10.10 503 589 6.5E-13 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Gene3D G3DSA:2.40.10.10 134 198 3.5E-12 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 SMART SM00020 90 333 4.0E-48 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 SUPERFAMILY SSF69318 333 557 1.18E-24 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 287 298 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 128 143 2.9E-10 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 286 298 2.9E-10 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 190 204 2.9E-10 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 PANTHER PTHR24256 87 341 3.5E-48 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Pfam PF00089 Trypsin 91 330 5.7E-41 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Gene3D G3DSA:2.40.10.10 91 133 2.0E-16 T 16-09-2016 Spa2297_RS22620 280ab72404d17791c71b148dc2c7a847 590 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 489 551 7.5E-7 T 16-09-2016 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 16-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 SUPERFAMILY SSF53383 27 372 5.45E-90 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 PANTHER PTHR13693 28 372 2.9E-132 T 16-09-2016 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 Pfam PF00155 Aminotransferase class I and II 31 370 9.3E-53 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 PANTHER PTHR13693:SF53 28 372 2.9E-132 T 16-09-2016 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 Gene3D G3DSA:3.90.1150.10 262 370 8.3E-14 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS04530 e140d7e73cfa2c5a34b048bbe4c090e2 375 Gene3D G3DSA:3.40.640.10 48 261 6.9E-73 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 Gene3D G3DSA:3.20.20.40 55 340 7.0E-98 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 121 137 - T 16-09-2016 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PIRSF PIRSF001100 3 341 8.3E-92 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 Pfam PF01341 Glycosyl hydrolases family 6 69 324 5.2E-81 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PANTHER PTHR34876 5 341 4.2E-114 T 16-09-2016 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 231 241 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 76 95 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 281 301 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 116 129 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 144 159 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 261 274 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 305 319 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 PRINTS PR00733 Glycosyl hydrolase family 6 signature 201 214 5.3E-39 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS12135 507a8b3a5af15af8b00567b9616c9bb3 341 SUPERFAMILY SSF51989 47 340 1.44E-88 T 16-09-2016 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 Spa2297_RS02305 b98d0e462c4b687b9b193c555d4d5dce 194 SUPERFAMILY SSF50346 63 180 6.28E-6 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS02305 b98d0e462c4b687b9b193c555d4d5dce 194 Pfam PF05239 PRC-barrel domain 93 153 3.5E-8 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS02305 b98d0e462c4b687b9b193c555d4d5dce 194 Gene3D G3DSA:2.30.30.240 4 71 2.4E-5 T 16-09-2016 Spa2297_RS04630 de98017197e85e35e8f9e6f6a428d6c3 289 SUPERFAMILY SSF53474 58 249 7.29E-29 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04630 de98017197e85e35e8f9e6f6a428d6c3 289 Gene3D G3DSA:3.40.50.1820 41 288 1.0E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04630 de98017197e85e35e8f9e6f6a428d6c3 289 PANTHER PTHR10992:SF107 51 289 4.4E-18 T 16-09-2016 Spa2297_RS04630 de98017197e85e35e8f9e6f6a428d6c3 289 Pfam PF01674 Lipase (class 2) 61 244 4.9E-11 T 16-09-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 Spa2297_RS04630 de98017197e85e35e8f9e6f6a428d6c3 289 PANTHER PTHR10992 51 289 4.4E-18 T 16-09-2016 Spa2297_RS14435 a246c365da184ef17f6a7384aebac8c1 220 SMART SM00943 28 209 4.4E-37 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS14435 a246c365da184ef17f6a7384aebac8c1 220 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 28 201 1.8E-23 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS05810 b284b007bb56bbd53a300e1d5041a559 183 Gene3D G3DSA:3.30.428.10 41 180 1.6E-38 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS05810 b284b007bb56bbd53a300e1d5041a559 183 Pfam PF01230 HIT domain 56 147 1.2E-10 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS05810 b284b007bb56bbd53a300e1d5041a559 183 PANTHER PTHR23089:SF16 1 180 1.6E-99 T 16-09-2016 Spa2297_RS05810 b284b007bb56bbd53a300e1d5041a559 183 SUPERFAMILY SSF54197 18 172 2.01E-40 T 16-09-2016 IPR011146 HIT-like domain GO:0003824 Spa2297_RS05810 b284b007bb56bbd53a300e1d5041a559 183 PANTHER PTHR23089 1 180 1.6E-99 T 16-09-2016 IPR001310 Histidine triad (HIT) protein Spa2297_RS11800 550b0c523da1cac670e276cb77bda371 589 Pfam PF06276 Ferric iron reductase FhuF-like transporter 410 566 7.6E-39 T 16-09-2016 IPR022770 Ferric iron reductase FhuF domain Spa2297_RS11800 550b0c523da1cac670e276cb77bda371 589 Pfam PF04183 IucA / IucC family 138 388 2.4E-77 T 16-09-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 Spa2297_RS11800 550b0c523da1cac670e276cb77bda371 589 PANTHER PTHR34384:SF5 1 589 8.7E-291 T 16-09-2016 Spa2297_RS11800 550b0c523da1cac670e276cb77bda371 589 PANTHER PTHR34384 1 589 8.7E-291 T 16-09-2016 Spa2297_RS09320 cf3a9063a6d2920e776ecb70ab7961b2 334 PANTHER PTHR32243 27 334 1.2E-115 T 16-09-2016 Spa2297_RS09320 cf3a9063a6d2920e776ecb70ab7961b2 334 SUPERFAMILY SSF161098 89 318 1.44E-57 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS09320 cf3a9063a6d2920e776ecb70ab7961b2 334 PANTHER PTHR32243:SF40 27 334 1.2E-115 T 16-09-2016 Spa2297_RS09320 cf3a9063a6d2920e776ecb70ab7961b2 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 322 4.2E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS09320 cf3a9063a6d2920e776ecb70ab7961b2 334 Gene3D G3DSA:1.10.3720.10 32 323 7.7E-61 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 Pfam PF04185 Phosphoesterase family 44 429 2.7E-112 T 16-09-2016 IPR007312 Phosphoesterase GO:0016788 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 681 1.4E-258 T 16-09-2016 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 PANTHER PTHR31956 4 508 4.4E-198 T 16-09-2016 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 PANTHER PTHR31956:SF1 4 508 4.4E-198 T 16-09-2016 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 Pfam PF05506 Domain of unknown function (DUF756) 598 668 3.2E-17 T 16-09-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 Spa2297_RS27840 10e3499414c8ad4b7a2f791d27ef0480 684 Pfam PF05506 Domain of unknown function (DUF756) 497 583 1.4E-19 T 16-09-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 536 4.2E-58 T 16-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 Pfam PF05681 Fumarate hydratase (Fumerase) 47 324 7.9E-89 T 16-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 74 325 1.9E-33 T 16-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 PANTHER PTHR30389 1 537 0.0 T 16-09-2016 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 Gene3D G3DSA:3.20.130.10 351 536 5.1E-75 T 16-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 16-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 PANTHER PTHR30389:SF0 1 537 0.0 T 16-09-2016 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 Pfam PF05683 Fumarase C-terminus 330 537 2.2E-92 T 16-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 SUPERFAMILY SSF117457 361 536 3.66E-62 T 16-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spa2297_RS21355 1c5fa0c48d6a9e776b1ef315a0c029af 555 PIRSF PIRSF001394 28 550 5.7E-228 T 16-09-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 Spa2297_RS00875 e97f0c05bace371575a67109bc354c31 348 PANTHER PTHR11732 14 346 9.2E-179 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS00875 e97f0c05bace371575a67109bc354c31 348 Gene3D G3DSA:3.20.20.100 14 329 3.8E-81 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS00875 e97f0c05bace371575a67109bc354c31 348 SUPERFAMILY SSF51430 14 329 2.1E-86 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS00875 e97f0c05bace371575a67109bc354c31 348 Pfam PF00248 Aldo/keto reductase family 29 329 5.7E-66 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS00875 e97f0c05bace371575a67109bc354c31 348 PANTHER PTHR11732:SF191 14 346 9.2E-179 T 16-09-2016 Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 PANTHER PTHR11516 39 374 2.4E-121 T 16-09-2016 Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 Pfam PF00676 Dehydrogenase E1 component 66 342 7.7E-74 T 16-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 PANTHER PTHR11516:SF1 39 374 2.4E-121 T 16-09-2016 Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 36 363 4.6E-128 T 16-09-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 Gene3D G3DSA:3.40.50.970 31 363 3.4E-118 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS16810 2801bb295475e3aef38629682e7e14f4 392 SUPERFAMILY SSF52518 45 367 2.32E-94 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 Gene3D G3DSA:1.20.144.10 16 185 3.0E-30 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 Pfam PF01569 PAP2 superfamily 77 185 6.1E-19 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 SMART SM00014 69 183 2.4E-13 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 SUPERFAMILY SSF48317 45 188 1.83E-31 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 PANTHER PTHR14969 44 179 2.6E-30 T 16-09-2016 Spa2297_RS18410 116bfd3102cdccd47dc9516898e37689 226 PANTHER PTHR14969:SF24 44 179 2.6E-30 T 16-09-2016 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 PANTHER PTHR22854 1 262 2.1E-92 T 16-09-2016 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 PANTHER PTHR22854:SF2 1 262 2.1E-92 T 16-09-2016 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 256 3.3E-72 T 16-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 258 32.124 T 16-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 SUPERFAMILY SSF51366 12 258 4.36E-73 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS23970 487f33fed167f63a53a3ba6bbd3ec577 280 Gene3D G3DSA:3.20.20.70 2 258 8.6E-88 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 SUPERFAMILY SSF46689 28 99 3.23E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 Pfam PF01418 Helix-turn-helix domain, rpiR family 27 100 3.0E-13 T 16-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 Gene3D G3DSA:3.40.50.10490 130 288 3.6E-40 T 16-09-2016 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 SUPERFAMILY SSF53697 121 287 5.87E-39 T 16-09-2016 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 PANTHER PTHR30514:SF1 27 290 3.6E-64 T 16-09-2016 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 PANTHER PTHR30514 27 290 3.6E-64 T 16-09-2016 Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 Gene3D G3DSA:1.10.10.10 27 101 2.2E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS14745 0704cf52d55ccfa5adaee3d40be2d00a 314 Pfam PF01380 SIS domain 153 282 1.3E-22 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS16970 ddc4c8ebff1ca40f0e1f0a376d999137 201 Pfam PF05685 Putative restriction endonuclease 32 157 1.5E-13 T 16-09-2016 IPR008538 Domain of unknown function DUF820 Spa2297_RS16970 ddc4c8ebff1ca40f0e1f0a376d999137 201 SUPERFAMILY SSF52980 28 152 3.91E-10 T 16-09-2016 IPR011335 Restriction endonuclease type II-like Spa2297_RS16970 ddc4c8ebff1ca40f0e1f0a376d999137 201 Gene3D G3DSA:3.90.1570.10 33 153 4.5E-12 T 16-09-2016 IPR012296 Nuclease, putative, TT1808 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 SUPERFAMILY SSF56801 41 648 7.46E-126 T 16-09-2016 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Gene3D G3DSA:3.40.50.980 100 274 5.4E-28 T 16-09-2016 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 PANTHER PTHR24095:SF46 6 657 0.0 T 16-09-2016 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Gene3D G3DSA:3.30.300.30 528 618 3.0E-13 T 16-09-2016 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Pfam PF13193 AMP-binding enzyme C-terminal domain 542 617 9.2E-7 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 658 0.0 T 16-09-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 41 97 2.4E-13 T 16-09-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Pfam PF00501 AMP-binding enzyme 102 529 7.1E-47 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 PANTHER PTHR24095 6 657 0.0 T 16-09-2016 Spa2297_RS05135 e71441b7fc65128a3984c18232f22163 658 Gene3D G3DSA:3.40.50.980 275 434 3.3E-15 T 16-09-2016 Spa2297_RS27205 80510c1911e082785613a14271bd14ed 465 PIRSF PIRSF006060 16 464 3.9E-66 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS27205 80510c1911e082785613a14271bd14ed 465 Pfam PF13520 Amino acid permease 35 431 3.8E-49 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS27205 80510c1911e082785613a14271bd14ed 465 PANTHER PTHR11785 3 459 3.3E-168 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS27205 80510c1911e082785613a14271bd14ed 465 PANTHER PTHR11785:SF259 3 459 3.3E-168 T 16-09-2016 Spa2297_RS02785 bbcf9f79604bf44da0c59c6437da3e79 433 Gene3D G3DSA:1.50.10.110 74 424 3.3E-94 T 16-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Spa2297_RS02785 bbcf9f79604bf44da0c59c6437da3e79 433 SUPERFAMILY SSF48230 98 377 8.79E-54 T 16-09-2016 IPR008929 Chondroitin AC/alginate lyase Spa2297_RS02785 bbcf9f79604bf44da0c59c6437da3e79 433 PANTHER PTHR41379:SF1 10 427 4.0E-78 T 16-09-2016 Spa2297_RS02785 bbcf9f79604bf44da0c59c6437da3e79 433 PANTHER PTHR41379 10 427 4.0E-78 T 16-09-2016 Spa2297_RS02785 bbcf9f79604bf44da0c59c6437da3e79 433 Pfam PF05426 Alginate lyase 92 376 2.3E-88 T 16-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Spa2297_RS24125 e547d9b6ab66f115c0004c5202dd30fe 176 Pfam PF00583 Acetyltransferase (GNAT) family 56 149 2.9E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS24125 e547d9b6ab66f115c0004c5202dd30fe 176 SUPERFAMILY SSF55729 2 168 6.62E-18 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24125 e547d9b6ab66f115c0004c5202dd30fe 176 Gene3D G3DSA:3.40.630.30 12 155 5.2E-18 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 Pfam PF00005 ABC transporter 332 473 5.8E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 Pfam PF00005 ABC transporter 20 170 6.1E-23 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 PANTHER PTHR24220 332 411 4.2E-189 T 16-09-2016 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 PANTHER PTHR24220:SF459 332 411 4.2E-189 T 16-09-2016 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 Gene3D G3DSA:3.40.50.300 1 231 4.0E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 SUPERFAMILY SSF52540 307 533 2.41E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 Gene3D G3DSA:3.40.50.300 318 533 6.6E-52 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 SUPERFAMILY SSF52540 2 226 2.73E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 PANTHER PTHR24220 3 286 4.2E-189 T 16-09-2016 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 PANTHER PTHR24220:SF459 3 286 4.2E-189 T 16-09-2016 Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 SMART SM00382 28 219 5.6E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS09720 c99f64a0cbc7e5e16fbc245b6153a4a9 563 SMART SM00382 341 521 1.2E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 SUPERFAMILY SSF52540 453 686 1.11E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 SUPERFAMILY SSF52540 187 266 1.11E-39 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 PANTHER PTHR11070:SF25 405 686 1.6E-198 T 16-09-2016 Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 PANTHER PTHR11070:SF25 93 359 1.6E-198 T 16-09-2016 Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 Pfam PF13245 Part of AAA domain 205 277 3.9E-11 T 16-09-2016 Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 Gene3D G3DSA:3.40.50.300 541 686 5.8E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 PANTHER PTHR11070 405 686 1.6E-198 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 PANTHER PTHR11070 93 359 1.6E-198 T 16-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 Gene3D G3DSA:3.40.50.300 392 540 9.5E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15215 422db62f45421d08d7c6188443206317 690 Gene3D G3DSA:3.40.50.300 194 262 9.5E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21345 575500f02d647518452e480d41bb8e99 234 Gene3D G3DSA:2.40.380.10 22 214 1.4E-73 T 16-09-2016 IPR007295 Domain of unknown function DUF402 Spa2297_RS21345 575500f02d647518452e480d41bb8e99 234 Pfam PF04167 Protein of unknown function (DUF402) 104 168 3.4E-14 T 16-09-2016 IPR007295 Domain of unknown function DUF402 Spa2297_RS21345 575500f02d647518452e480d41bb8e99 234 SUPERFAMILY SSF159234 47 217 1.12E-46 T 16-09-2016 Spa2297_RS11550 7fbcb2b298771f59967cd8ec979a55b1 186 Gene3D G3DSA:3.40.630.30 6 181 8.1E-50 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11550 7fbcb2b298771f59967cd8ec979a55b1 186 PANTHER PTHR13256:SF21 1 185 4.2E-70 T 16-09-2016 Spa2297_RS11550 7fbcb2b298771f59967cd8ec979a55b1 186 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 5.2E-22 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS11550 7fbcb2b298771f59967cd8ec979a55b1 186 SUPERFAMILY SSF55729 6 175 8.58E-45 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11550 7fbcb2b298771f59967cd8ec979a55b1 186 PANTHER PTHR13256 1 185 4.2E-70 T 16-09-2016 Spa2297_RS04145 117095b0300288bfabeee53296c7b7e5 204 PANTHER PTHR11711:SF117 21 190 1.5E-55 T 16-09-2016 Spa2297_RS04145 117095b0300288bfabeee53296c7b7e5 204 Gene3D G3DSA:3.40.50.300 16 190 1.7E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04145 117095b0300288bfabeee53296c7b7e5 204 SUPERFAMILY SSF52540 21 191 1.0E-19 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04145 117095b0300288bfabeee53296c7b7e5 204 PANTHER PTHR11711 21 190 1.5E-55 T 16-09-2016 Spa2297_RS04145 117095b0300288bfabeee53296c7b7e5 204 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 3.0E-26 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS19195 07bcafdbca084c56a007cd5dd160f64c 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.813 T 16-09-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 Spa2297_RS19195 07bcafdbca084c56a007cd5dd160f64c 119 PANTHER PTHR11058:SF5 2 119 2.1E-53 T 16-09-2016 Spa2297_RS19195 07bcafdbca084c56a007cd5dd160f64c 119 PANTHER PTHR11058 2 119 2.1E-53 T 16-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Spa2297_RS19195 07bcafdbca084c56a007cd5dd160f64c 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 1.8E-36 T 16-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Spa2297_RS23065 749da62d479edd8e48a9f8a0116a0f64 408 Gene3D G3DSA:2.40.440.10 252 378 5.5E-16 T 16-09-2016 Spa2297_RS23065 749da62d479edd8e48a9f8a0116a0f64 408 SUPERFAMILY SSF141523 252 377 2.09E-19 T 16-09-2016 Spa2297_RS23065 749da62d479edd8e48a9f8a0116a0f64 408 PANTHER PTHR30582:SF2 7 404 1.0E-127 T 16-09-2016 Spa2297_RS23065 749da62d479edd8e48a9f8a0116a0f64 408 Pfam PF03734 L,D-transpeptidase catalytic domain 252 377 5.1E-9 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS23065 749da62d479edd8e48a9f8a0116a0f64 408 PANTHER PTHR30582 7 404 1.0E-127 T 16-09-2016 Spa2297_RS17830 be53b111e937dd06c1b346d2b963ecf5 112 PANTHER PTHR38839:SF3 6 86 7.5E-37 T 16-09-2016 Spa2297_RS17830 be53b111e937dd06c1b346d2b963ecf5 112 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 15.999 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS17830 be53b111e937dd06c1b346d2b963ecf5 112 Pfam PF02467 Transcription factor WhiB 7 69 8.8E-25 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS17830 be53b111e937dd06c1b346d2b963ecf5 112 PANTHER PTHR38839 6 86 7.5E-37 T 16-09-2016 Spa2297_RS11490 f95a5d4139e1a9aa0076c7f2578d368f 438 Gene3D G3DSA:3.30.470.20 239 319 1.9E-7 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS11490 f95a5d4139e1a9aa0076c7f2578d368f 438 SUPERFAMILY SSF56059 125 320 3.54E-21 T 16-09-2016 Spa2297_RS11490 f95a5d4139e1a9aa0076c7f2578d368f 438 Gene3D G3DSA:3.30.1490.20 122 211 1.4E-5 T 16-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 PANTHER PTHR34989 12 219 4.0E-45 T 16-09-2016 Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 PANTHER PTHR34989:SF1 12 219 4.0E-45 T 16-09-2016 Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 Pfam PF03729 Short repeat of unknown function (DUF308) 165 214 2.8E-7 T 16-09-2016 IPR005325 Protein of unknown function DUF308, membrane Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 Pfam PF03729 Short repeat of unknown function (DUF308) 108 177 4.7E-11 T 16-09-2016 IPR005325 Protein of unknown function DUF308, membrane Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 Pfam PF03729 Short repeat of unknown function (DUF308) 52 121 2.7E-14 T 16-09-2016 IPR005325 Protein of unknown function DUF308, membrane Spa2297_RS15920 80e26cd7e35ea7fcc9fbd18cc6324834 220 SUPERFAMILY SSF103473 25 213 9.55E-5 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 PANTHER PTHR23090:SF7 9 276 6.1E-146 T 16-09-2016 Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 Gene3D G3DSA:3.40.50.620 12 274 1.0E-69 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 SUPERFAMILY SSF52402 11 274 1.83E-74 T 16-09-2016 Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 PANTHER PTHR23090 9 276 6.1E-146 T 16-09-2016 Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 23 276 32.514 T 16-09-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 27 274 1.1E-63 T 16-09-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 Spa2297_RS31030 2a909958b8be68ae9d0062dd55c1eef9 276 Pfam PF02540 NAD synthase 29 273 2.5E-64 T 16-09-2016 IPR022310 NAD/GMP synthase Spa2297_RS19420 7827e81a418cacf9c2ca022bc6d7f9d6 352 Gene3D G3DSA:3.40.50.970 18 253 5.2E-85 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS19420 7827e81a418cacf9c2ca022bc6d7f9d6 352 SUPERFAMILY SSF52518 28 351 7.68E-86 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS19420 7827e81a418cacf9c2ca022bc6d7f9d6 352 PANTHER PTHR18968:SF89 18 327 3.3E-126 T 16-09-2016 Spa2297_RS19420 7827e81a418cacf9c2ca022bc6d7f9d6 352 PANTHER PTHR18968 18 327 3.3E-126 T 16-09-2016 Spa2297_RS19420 7827e81a418cacf9c2ca022bc6d7f9d6 352 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 64 211 7.6E-30 T 16-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 PANTHER PTHR24220:SF336 28 370 1.2E-175 T 16-09-2016 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 Pfam PF00005 ABC transporter 55 205 6.4E-31 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 SUPERFAMILY SSF52540 26 276 1.04E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 346 2.3E-27 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 Gene3D G3DSA:3.40.50.300 25 279 3.3E-80 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 323 1.1E-17 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 SMART SM00382 63 255 2.9E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS21580 1ec6459d788fbe9d0d3dd504740d6b2a 381 PANTHER PTHR24220 28 370 1.2E-175 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 Gene3D G3DSA:3.30.460.20 28 176 1.1E-44 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 SUPERFAMILY SSF143865 31 304 9.55E-64 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 PANTHER PTHR21535 69 371 3.1E-63 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 Pfam PF01544 CorA-like Mg2+ transporter protein 68 362 9.9E-61 T 16-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 SUPERFAMILY SSF144083 307 368 7.06E-19 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 Gene3D G3DSA:1.20.58.340 295 371 8.3E-26 T 16-09-2016 Spa2297_RS21755 fe856e367fab6ddf0caf48290d831c6a 371 Gene3D G3DSA:1.20.58.340 177 293 2.0E-39 T 16-09-2016 Spa2297_RS30520 4060dad3b935834cb5ea1589f672b09c 279 PANTHER PTHR32251 2 273 5.9E-76 T 16-09-2016 Spa2297_RS30520 4060dad3b935834cb5ea1589f672b09c 279 Pfam PF06966 Protein of unknown function (DUF1295) 28 259 2.4E-71 T 16-09-2016 IPR010721 Protein of unknown function DUF1295 Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 37.455 T 16-09-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 SUPERFAMILY SSF51182 17 127 2.26E-17 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 8.0E-64 T 16-09-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 Gene3D G3DSA:2.60.120.10 25 112 7.2E-11 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 PANTHER PTHR39289 1 132 3.7E-57 T 16-09-2016 Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 Pfam PF06339 Ectoine synthase 2 127 5.8E-55 T 16-09-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 Spa2297_RS07445 3b21196af4352746d4eeaa211eb9f6a9 132 PANTHER PTHR39289:SF1 1 132 3.7E-57 T 16-09-2016 Spa2297_RS07020 e0cd8c415948615ef149e3885bda3472 382 Gene3D G3DSA:3.40.50.2000 191 354 1.2E-20 T 16-09-2016 Spa2297_RS07020 e0cd8c415948615ef149e3885bda3472 382 Pfam PF13579 Glycosyl transferase 4-like domain 27 169 1.1E-17 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS07020 e0cd8c415948615ef149e3885bda3472 382 PANTHER PTHR12526 27 380 5.0E-41 T 16-09-2016 Spa2297_RS07020 e0cd8c415948615ef149e3885bda3472 382 SUPERFAMILY SSF53756 27 376 1.74E-55 T 16-09-2016 Spa2297_RS07020 e0cd8c415948615ef149e3885bda3472 382 Pfam PF13692 Glycosyl transferases group 1 203 340 8.3E-22 T 16-09-2016 Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 PANTHER PTHR12862:SF5 4 325 4.0E-99 T 16-09-2016 Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 69 264 4.8E-15 T 16-09-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 SUPERFAMILY SSF53067 122 304 5.36E-37 T 16-09-2016 Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 PANTHER PTHR12862 4 325 4.0E-99 T 16-09-2016 Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 Gene3D G3DSA:3.30.420.40 160 189 2.2E-5 T 16-09-2016 Spa2297_RS03735 832c84482a98eb7d519071f024654b3f 325 Gene3D G3DSA:3.30.420.40 224 286 2.2E-5 T 16-09-2016 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 Gene3D G3DSA:3.30.565.10 318 486 6.9E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 9.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 9.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 441 9.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 9.2E-15 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 331 1.1E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SMART SM00388 264 331 1.8E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SMART SM00387 373 487 3.3E-32 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PANTHER PTHR24423 23 90 1.0E-64 T 16-09-2016 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 PANTHER PTHR24423 198 488 1.0E-64 T 16-09-2016 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 Gene3D G3DSA:1.10.287.130 256 317 5.9E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SUPERFAMILY SSF55874 320 486 5.24E-35 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SMART SM00304 204 256 7.6E-15 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SUPERFAMILY SSF47384 250 331 6.87E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 486 2.0E-19 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 Pfam PF00672 HAMP domain 189 252 2.4E-14 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS02505 a66227dd3d6671dae96d707a534b3088 503 SUPERFAMILY SSF158472 204 253 8.11E-8 T 16-09-2016 Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 SUPERFAMILY SSF51679 4 303 4.19E-67 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 3.6E-90 T 16-09-2016 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 Pfam PF00296 Luciferase-like monooxygenase 8 248 1.2E-53 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 PANTHER PTHR30011 4 251 4.6E-93 T 16-09-2016 Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 PANTHER PTHR30011:SF5 4 251 4.6E-93 T 16-09-2016 Spa2297_RS25090 209f75ed870a48d77afed724e7642994 307 Gene3D G3DSA:3.20.20.30 8 306 1.5E-75 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS20630 74dd7ec7a671cff6249d36f76be1976f 421 Gene3D G3DSA:1.25.40.10 93 137 2.0E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS20630 74dd7ec7a671cff6249d36f76be1976f 421 SUPERFAMILY SSF48452 49 137 7.94E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 PANTHER PTHR11609:SF5 7 172 1.0E-87 T 16-09-2016 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 PANTHER PTHR11609 7 172 1.0E-87 T 16-09-2016 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 11 165 9.6E-65 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 11 162 32.554 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 SMART SM01001 9 158 1.3E-98 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 SUPERFAMILY SSF52255 9 168 1.83E-66 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 PIRSF PIRSF001338 7 169 3.5E-69 T 16-09-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 Gene3D G3DSA:3.40.50.7700 8 166 1.9E-74 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS13255 7ad92bd5062829776ec39b719dac6751 180 Pfam PF00731 AIR carboxylase 11 156 2.2E-66 T 16-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 Spa2297_RS26380 828a3c9f2e9bb038c9812a62c501fbec 421 SUPERFAMILY SSF53300 43 227 7.53E-23 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS26380 828a3c9f2e9bb038c9812a62c501fbec 421 Gene3D G3DSA:3.40.50.410 43 227 5.0E-12 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS26380 828a3c9f2e9bb038c9812a62c501fbec 421 PANTHER PTHR10579 43 220 8.2E-29 T 16-09-2016 Spa2297_RS26380 828a3c9f2e9bb038c9812a62c501fbec 421 Pfam PF13519 von Willebrand factor type A domain 43 159 3.3E-9 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS26380 828a3c9f2e9bb038c9812a62c501fbec 421 SMART SM00327 40 230 1.0E-16 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS28000 42b77e409f011c8b743b3d9e274dcc87 98 PANTHER PTHR37828 1 97 4.8E-31 T 16-09-2016 Spa2297_RS28000 42b77e409f011c8b743b3d9e274dcc87 98 SUPERFAMILY SSF54909 1 83 1.31E-19 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS28000 42b77e409f011c8b743b3d9e274dcc87 98 PANTHER PTHR37828:SF1 1 97 4.8E-31 T 16-09-2016 Spa2297_RS28000 42b77e409f011c8b743b3d9e274dcc87 98 Pfam PF03795 YCII-related domain 1 81 2.5E-18 T 16-09-2016 IPR005545 YCII-related Spa2297_RS28000 42b77e409f011c8b743b3d9e274dcc87 98 Gene3D G3DSA:3.30.70.1060 11 81 2.4E-10 T 16-09-2016 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 SUPERFAMILY SSF48264 5 422 1.44E-100 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00385 P450 superfamily signature 288 299 1.2E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00385 P450 superfamily signature 236 253 1.2E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00385 P450 superfamily signature 362 371 1.2E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00385 P450 superfamily signature 371 382 1.2E-13 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PANTHER PTHR24305 2 423 4.7E-89 T 16-09-2016 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 Gene3D G3DSA:1.10.630.10 6 423 2.2E-107 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 371 394 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 327 351 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 361 371 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 225 242 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 245 271 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 PRINTS PR00463 E-class P450 group I signature 12 31 3.1E-25 T 16-09-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 Spa2297_RS01435 a06b618740e38fe8c981d8df761a9605 431 Pfam PF00067 Cytochrome P450 8 406 7.3E-71 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS31945 e58cf9cb6e2f26c0b7da93af6213f09d 104 Pfam PF05121 Gas vesicle protein K 4 85 2.4E-20 T 16-09-2016 IPR007805 Gas vesicle protein GvpK GO:0031412 Spa2297_RS31945 e58cf9cb6e2f26c0b7da93af6213f09d 104 PANTHER PTHR40137:SF2 6 92 1.4E-13 T 16-09-2016 Spa2297_RS31945 e58cf9cb6e2f26c0b7da93af6213f09d 104 PANTHER PTHR40137 6 92 1.4E-13 T 16-09-2016 Spa2297_RS33780 ea14897368feaa5d950be7754e58cf2d 260 PANTHER PTHR24362 1 254 7.2E-27 T 16-09-2016 Spa2297_RS33780 ea14897368feaa5d950be7754e58cf2d 260 Pfam PF00069 Protein kinase domain 20 74 5.7E-8 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS33780 ea14897368feaa5d950be7754e58cf2d 260 SUPERFAMILY SSF56112 1 109 3.56E-16 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS33780 ea14897368feaa5d950be7754e58cf2d 260 Gene3D G3DSA:1.10.510.10 2 116 2.7E-14 T 16-09-2016 Spa2297_RS33780 ea14897368feaa5d950be7754e58cf2d 260 PANTHER PTHR24362:SF282 1 254 7.2E-27 T 16-09-2016 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 PANTHER PTHR21712 1 154 1.7E-72 T 16-09-2016 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 SMART SM00240 97 148 1.2E-13 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 SUPERFAMILY SSF49879 48 170 2.1E-29 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 PANTHER PTHR21712:SF36 1 154 1.7E-72 T 16-09-2016 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 Pfam PF00498 FHA domain 98 163 1.4E-16 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS16740 0df2beb4e0ac67151645b5f987b14af3 171 Gene3D G3DSA:2.60.200.20 77 170 1.7E-28 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS11325 5c76a86367c5a557f312e3f48eaa1b13 137 Pfam PF01152 Bacterial-like globin 16 132 5.1E-36 T 16-09-2016 IPR001486 Truncated hemoglobin GO:0019825 Spa2297_RS11325 5c76a86367c5a557f312e3f48eaa1b13 137 SUPERFAMILY SSF46458 15 135 1.42E-38 T 16-09-2016 IPR009050 Globin-like Spa2297_RS11325 5c76a86367c5a557f312e3f48eaa1b13 137 Gene3D G3DSA:1.10.490.10 14 135 1.8E-47 T 16-09-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Spa2297_RS11325 5c76a86367c5a557f312e3f48eaa1b13 137 PANTHER PTHR10681 12 122 8.3E-28 T 16-09-2016 Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 Gene3D G3DSA:2.20.25.10 1 44 1.6E-19 T 16-09-2016 Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 PANTHER PTHR33797:SF2 1 137 4.0E-67 T 16-09-2016 Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 PANTHER PTHR33797 1 137 4.0E-67 T 16-09-2016 Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 SUPERFAMILY SSF82784 4 136 8.24E-44 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 135 1.2E-54 T 16-09-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 Pfam PF02566 OsmC-like protein 38 134 4.9E-21 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS12910 2b880a2421ccca928409d92f95b9bb81 137 Gene3D G3DSA:3.30.300.20 45 136 5.3E-37 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS31200 66a8860297cdc3bb2588271efb453002 644 SUPERFAMILY SSF51445 17 332 5.51E-45 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31200 66a8860297cdc3bb2588271efb453002 644 Gene3D G3DSA:3.20.20.80 6 333 4.4E-41 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS31200 66a8860297cdc3bb2588271efb453002 644 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 35 294 1.2E-11 T 16-09-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Spa2297_RS31200 66a8860297cdc3bb2588271efb453002 644 PANTHER PTHR31451 137 347 1.0E-24 T 16-09-2016 Spa2297_RS22765 f91713055976d2978335a37288444ea7 866 SUPERFAMILY SSF52540 100 270 1.17E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22765 f91713055976d2978335a37288444ea7 866 Gene3D G3DSA:3.40.50.300 102 213 1.1E-4 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26685 badc417c1172c17d676c42e4935d557d 141 Pfam PF13279 Thioesterase-like superfamily 18 124 6.2E-9 T 16-09-2016 Spa2297_RS26685 badc417c1172c17d676c42e4935d557d 141 Gene3D G3DSA:3.10.129.10 10 128 1.1E-24 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS26685 badc417c1172c17d676c42e4935d557d 141 SUPERFAMILY SSF54637 10 128 9.13E-22 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS26685 badc417c1172c17d676c42e4935d557d 141 PANTHER PTHR31793 11 128 8.5E-20 T 16-09-2016 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 Gene3D G3DSA:3.40.47.10 277 414 1.5E-36 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 251 1.2E-27 T 16-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 SUPERFAMILY SSF53901 222 414 2.15E-45 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 SUPERFAMILY SSF53901 12 259 2.71E-50 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 Gene3D G3DSA:3.40.47.10 11 267 1.2E-42 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 PANTHER PTHR11712 1 414 5.7E-66 T 16-09-2016 Spa2297_RS22465 7ae520841d363e31564d5fb825629e60 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 374 8.2E-24 T 16-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 342 60.485 T 16-09-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 SUPERFAMILY SSF53901 10 341 7.27E-59 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 1.6E-25 T 16-09-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 PANTHER PTHR18919 36 343 7.0E-201 T 16-09-2016 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 Gene3D G3DSA:3.40.47.10 171 340 1.6E-46 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 341 1.6E-107 T 16-09-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 252 341 4.6E-31 T 16-09-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 PANTHER PTHR18919:SF103 36 343 7.0E-201 T 16-09-2016 Spa2297_RS10040 82d731e60f74d820312023e0617c65de 343 Gene3D G3DSA:3.40.47.10 13 170 6.2E-54 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS09420 954cc7dd7264fb46b9484c6eb7edf335 278 PANTHER PTHR30294 16 278 5.3E-118 T 16-09-2016 Spa2297_RS09420 954cc7dd7264fb46b9484c6eb7edf335 278 PANTHER PTHR30294:SF24 16 278 5.3E-118 T 16-09-2016 Spa2297_RS09420 954cc7dd7264fb46b9484c6eb7edf335 278 Pfam PF01061 ABC-2 type transporter 31 243 2.2E-34 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS09420 954cc7dd7264fb46b9484c6eb7edf335 278 PIRSF PIRSF006648 3 278 2.1E-81 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS08870 32c5538584cbe13be37799a542efd248 133 Gene3D G3DSA:3.40.50.2300 3 131 1.2E-10 T 16-09-2016 Spa2297_RS08870 32c5538584cbe13be37799a542efd248 133 SUPERFAMILY SSF52172 5 131 3.98E-8 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS30170 f033e24541d1af4f526ad088420e676b 377 PANTHER PTHR30482 316 367 8.2E-161 T 16-09-2016 Spa2297_RS30170 f033e24541d1af4f526ad088420e676b 377 PANTHER PTHR30482:SF5 2 300 8.2E-161 T 16-09-2016 Spa2297_RS30170 f033e24541d1af4f526ad088420e676b 377 PANTHER PTHR30482:SF5 316 367 8.2E-161 T 16-09-2016 Spa2297_RS30170 f033e24541d1af4f526ad088420e676b 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 330 1.0E-31 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS30170 f033e24541d1af4f526ad088420e676b 377 PANTHER PTHR30482 2 300 8.2E-161 T 16-09-2016 Spa2297_RS12105 881c4af7d1cf9f0224ce0e64d703af55 201 PANTHER PTHR34823 1 201 3.2E-84 T 16-09-2016 Spa2297_RS12105 881c4af7d1cf9f0224ce0e64d703af55 201 SUPERFAMILY SSF81296 30 201 2.1E-57 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS12105 881c4af7d1cf9f0224ce0e64d703af55 201 PANTHER PTHR34823:SF1 1 201 3.2E-84 T 16-09-2016 Spa2297_RS12105 881c4af7d1cf9f0224ce0e64d703af55 201 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 30 199 3.7E-42 T 16-09-2016 IPR004302 Chitin-binding protein, N-terminal Spa2297_RS12105 881c4af7d1cf9f0224ce0e64d703af55 201 Gene3D G3DSA:2.70.50.50 30 201 3.7E-62 T 16-09-2016 Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 Gene3D G3DSA:3.30.750.24 18 120 1.8E-26 T 16-09-2016 IPR002645 STAS domain Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 Pfam PF13466 STAS domain 29 106 1.1E-14 T 16-09-2016 IPR002645 STAS domain Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 SUPERFAMILY SSF52091 18 119 2.75E-23 T 16-09-2016 IPR002645 STAS domain Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 PANTHER PTHR33495:SF1 1 119 1.4E-51 T 16-09-2016 Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 PANTHER PTHR33495 1 119 1.4E-51 T 16-09-2016 Spa2297_RS30325 567553afedf0f67d813b6444784cdf24 121 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 18 117 8.3E-16 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS02380 3e77fd43228645af81b6bb1e82b0076d 89 PANTHER PTHR33884 1 89 2.8E-33 T 16-09-2016 Spa2297_RS02380 3e77fd43228645af81b6bb1e82b0076d 89 PANTHER PTHR33884:SF1 1 89 2.8E-33 T 16-09-2016 Spa2297_RS14625 a30acc2454a1fda5cca470b8c96171b5 84 Pfam PF10745 Protein of unknown function (DUF2530) 18 78 1.0E-8 T 16-09-2016 IPR019681 Protein of unknown function DUF2530 Spa2297_RS12235 b0c69d3bde0e1192fd3f04c3f182a3b4 182 Pfam PF01638 HxlR-like helix-turn-helix 20 105 1.4E-18 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS12235 b0c69d3bde0e1192fd3f04c3f182a3b4 182 PANTHER PTHR33204:SF9 1 160 2.1E-77 T 16-09-2016 Spa2297_RS12235 b0c69d3bde0e1192fd3f04c3f182a3b4 182 Gene3D G3DSA:1.10.10.10 5 106 2.8E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12235 b0c69d3bde0e1192fd3f04c3f182a3b4 182 SUPERFAMILY SSF46785 6 144 6.82E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS12235 b0c69d3bde0e1192fd3f04c3f182a3b4 182 PANTHER PTHR33204 1 160 2.1E-77 T 16-09-2016 Spa2297_RS22385 cd309e52725c08960dc388c04f7a0a81 217 Gene3D G3DSA:1.10.357.10 6 204 1.5E-32 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS22385 cd309e52725c08960dc388c04f7a0a81 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 69 2.9E-15 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22385 cd309e52725c08960dc388c04f7a0a81 217 PANTHER PTHR30328 1 217 5.0E-34 T 16-09-2016 Spa2297_RS22385 cd309e52725c08960dc388c04f7a0a81 217 SUPERFAMILY SSF46689 10 81 3.49E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS22385 cd309e52725c08960dc388c04f7a0a81 217 PANTHER PTHR30328:SF24 1 217 5.0E-34 T 16-09-2016 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.4E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.4E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 1.4E-10 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SMART SM00304 194 247 1.4E-11 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 PANTHER PTHR24423 188 464 7.0E-55 T 16-09-2016 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 Gene3D G3DSA:3.30.565.10 319 464 1.0E-27 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 464 4.2E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 Gene3D G3DSA:1.10.287.130 238 310 7.3E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SMART SM00387 355 468 1.2E-24 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SUPERFAMILY SSF158472 194 244 1.28E-6 T 16-09-2016 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 310 1.2E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 Pfam PF00672 HAMP domain 175 243 1.3E-15 T 16-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SUPERFAMILY SSF55874 316 464 7.86E-28 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SMART SM00388 248 315 4.5E-11 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS18695 91958f8ecdd3c22c1d61ec4ec6f15df3 483 SUPERFAMILY SSF47384 231 310 4.12E-12 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS13045 d54aa39973d23c6be76dd945c248a391 436 PANTHER PTHR33608:SF3 9 436 3.2E-177 T 16-09-2016 Spa2297_RS13045 d54aa39973d23c6be76dd945c248a391 436 Pfam PF01882 Protein of unknown function DUF58 192 277 3.5E-20 T 16-09-2016 IPR002881 Domain of unknown function DUF58 Spa2297_RS13045 d54aa39973d23c6be76dd945c248a391 436 Pfam PF01345 Domain of unknown function DUF11 27 96 1.5E-11 T 16-09-2016 IPR001434 Domain of unknown function DUF11 Spa2297_RS13045 d54aa39973d23c6be76dd945c248a391 436 PANTHER PTHR33608 9 436 3.2E-177 T 16-09-2016 Spa2297_RS16885 d2b28d3dad6fd0f70871698503d52fc6 414 Pfam PF00676 Dehydrogenase E1 component 92 361 2.0E-77 T 16-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Spa2297_RS16885 d2b28d3dad6fd0f70871698503d52fc6 414 PANTHER PTHR11516 82 410 7.6E-122 T 16-09-2016 Spa2297_RS16885 d2b28d3dad6fd0f70871698503d52fc6 414 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 53 400 1.6E-135 T 16-09-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 Spa2297_RS16885 d2b28d3dad6fd0f70871698503d52fc6 414 SUPERFAMILY SSF52518 79 404 2.78E-98 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS16885 d2b28d3dad6fd0f70871698503d52fc6 414 Gene3D G3DSA:3.40.50.970 24 400 1.0E-130 T 16-09-2016 IPR029061 Thiamin diphosphate-binding fold Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 562 960 2.8E-154 T 16-09-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 PANTHER PTHR30001:SF0 313 1323 0.0 T 16-09-2016 Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 SUPERFAMILY SSF50249 587 670 2.23E-14 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 Gene3D G3DSA:2.40.50.140 580 670 3.4E-28 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 Pfam PF10150 Ribonuclease E/G family 666 935 3.2E-108 T 16-09-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 SMART SM00316 585 664 1.6E-4 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS10970 e9940f48cf451f6a5108be78efb00f94 1324 PANTHER PTHR30001 313 1323 0.0 T 16-09-2016 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 Pfam PF00069 Protein kinase domain 18 268 5.3E-52 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 Gene3D G3DSA:1.10.510.10 88 269 5.1E-51 T 16-09-2016 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 PANTHER PTHR24362:SF160 11 274 1.2E-80 T 16-09-2016 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 SUPERFAMILY SSF56112 14 275 4.72E-71 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 Gene3D G3DSA:3.30.200.20 11 87 5.4E-25 T 16-09-2016 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 PANTHER PTHR24362 11 274 1.2E-80 T 16-09-2016 Spa2297_RS20155 8a6e16623964d7767439f913d9ed79d2 368 SMART SM00220 18 276 5.5E-65 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 SUPERFAMILY SSF52317 2 84 4.91E-27 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 SUPERFAMILY SSF52317 113 196 4.91E-27 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 Gene3D G3DSA:3.40.50.880 1 218 4.3E-56 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 PANTHER PTHR11019:SF131 5 219 1.1E-14 T 16-09-2016 Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 Pfam PF01965 DJ-1/PfpI family 122 195 4.3E-12 T 16-09-2016 IPR002818 DJ-1/PfpI Spa2297_RS29425 8578f871455b6fb23c4583f27c61afbc 229 PANTHER PTHR11019 5 219 1.1E-14 T 16-09-2016 Spa2297_RS01055 e1dce92cdd3a2cf6d0ae32089d60dbff 307 Gene3D G3DSA:1.10.3720.10 36 293 4.1E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01055 e1dce92cdd3a2cf6d0ae32089d60dbff 307 SUPERFAMILY SSF161098 41 307 6.28E-61 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01055 e1dce92cdd3a2cf6d0ae32089d60dbff 307 PANTHER PTHR32243 31 307 1.8E-125 T 16-09-2016 Spa2297_RS01055 e1dce92cdd3a2cf6d0ae32089d60dbff 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 292 3.6E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01055 e1dce92cdd3a2cf6d0ae32089d60dbff 307 PANTHER PTHR32243:SF31 31 307 1.8E-125 T 16-09-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 PANTHER PTHR13832 1 257 2.0E-86 T 16-09-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 SUPERFAMILY SSF81606 4 236 1.7E-66 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 Gene3D G3DSA:3.60.40.10 2 237 2.2E-74 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 PANTHER PTHR13832:SF226 1 257 2.0E-86 T 16-09-2016 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 Pfam PF00481 Protein phosphatase 2C 22 230 2.2E-11 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 SMART SM00331 11 237 1.3E-39 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16735 796329ffc74935eedd3ee8534269c60e 517 SMART SM00332 2 235 5.0E-28 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02580 68c270f2ed7e0ff857e54098a1568056 166 Pfam PF13302 Acetyltransferase (GNAT) domain 16 150 9.9E-20 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS02580 68c270f2ed7e0ff857e54098a1568056 166 SUPERFAMILY SSF55729 11 151 2.75E-26 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02580 68c270f2ed7e0ff857e54098a1568056 166 Gene3D G3DSA:3.40.630.30 8 151 2.6E-30 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS02580 68c270f2ed7e0ff857e54098a1568056 166 PANTHER PTHR13256 7 151 5.0E-21 T 16-09-2016 Spa2297_RS00150 dee5f9d7d24c62a1d8efe0f10ac18c0e 242 Gene3D G3DSA:3.40.50.720 1 195 1.6E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00150 dee5f9d7d24c62a1d8efe0f10ac18c0e 242 PANTHER PTHR14194 1 241 2.3E-119 T 16-09-2016 Spa2297_RS00150 dee5f9d7d24c62a1d8efe0f10ac18c0e 242 SUPERFAMILY SSF51735 1 217 1.34E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS00150 dee5f9d7d24c62a1d8efe0f10ac18c0e 242 PANTHER PTHR14194:SF69 1 241 2.3E-119 T 16-09-2016 Spa2297_RS00150 dee5f9d7d24c62a1d8efe0f10ac18c0e 242 Pfam PF13460 NAD(P)H-binding 7 172 1.7E-13 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS03955 c0606dcc3591238cdc3ebadc014dc2ed 209 Pfam PF07681 DoxX 47 146 1.9E-6 T 16-09-2016 IPR032808 DoxX family Spa2297_RS23180 efde6092e99e104670bd0dab81302574 219 Pfam PF03458 UPF0126 domain 13 87 9.8E-20 T 16-09-2016 IPR005115 Uncharacterised domain UPF0126 Spa2297_RS23180 efde6092e99e104670bd0dab81302574 219 Pfam PF03458 UPF0126 domain 99 173 3.2E-20 T 16-09-2016 IPR005115 Uncharacterised domain UPF0126 Spa2297_RS23180 efde6092e99e104670bd0dab81302574 219 PANTHER PTHR30506 5 219 4.7E-96 T 16-09-2016 Spa2297_RS23180 efde6092e99e104670bd0dab81302574 219 PANTHER PTHR30506:SF3 5 219 4.7E-96 T 16-09-2016 Spa2297_RS15490 abe10ed1f8f3e5a3e74a9db80e088f02 206 SUPERFAMILY SSF109755 41 199 3.66E-5 T 16-09-2016 Spa2297_RS15490 abe10ed1f8f3e5a3e74a9db80e088f02 206 PANTHER PTHR37298 1 206 1.9E-79 T 16-09-2016 Spa2297_RS15490 abe10ed1f8f3e5a3e74a9db80e088f02 206 Pfam PF01865 Protein of unknown function DUF47 7 203 6.7E-30 T 16-09-2016 IPR018445 Putative phosphate transport regulator Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 SMART SM00382 49 235 1.7E-18 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 Gene3D G3DSA:3.40.50.300 20 238 1.8E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 PANTHER PTHR24220:SF559 22 235 1.6E-115 T 16-09-2016 Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 SUPERFAMILY SSF52540 21 239 2.54E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 Pfam PF00005 ABC transporter 40 186 6.9E-33 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29595 c65d93301b1ba703125c0d61c99073c0 263 PANTHER PTHR24220 22 235 1.6E-115 T 16-09-2016 Spa2297_RS03620 329da4c554a836d05e3da29de8fb5c15 190 Pfam PF01841 Transglutaminase-like superfamily 29 104 9.4E-9 T 16-09-2016 IPR002931 Transglutaminase-like Spa2297_RS03620 329da4c554a836d05e3da29de8fb5c15 190 SUPERFAMILY SSF54001 24 136 8.41E-18 T 16-09-2016 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 36 414 1.8E-95 T 16-09-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 Gene3D G3DSA:1.20.1250.20 50 220 1.2E-29 T 16-09-2016 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 91 107 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 Pfam PF07690 Major Facilitator Superfamily 49 387 4.6E-40 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 PANTHER PTHR23502 3 416 1.1E-149 T 16-09-2016 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 SUPERFAMILY SSF103473 19 424 9.68E-62 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 PANTHER PTHR23502:SF19 3 416 1.1E-149 T 16-09-2016 Spa2297_RS09530 5d3bbbd149d05bf0288236d10d352bc3 435 Gene3D G3DSA:1.20.1250.20 236 425 8.3E-7 T 16-09-2016 Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 Gene3D G3DSA:3.40.710.10 144 494 7.2E-86 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 PANTHER PTHR30627 1 494 5.4E-201 T 16-09-2016 Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 Gene3D G3DSA:3.90.1310.10 72 143 7.5E-8 T 16-09-2016 Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 PANTHER PTHR30627:SF3 1 494 5.4E-201 T 16-09-2016 Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 Pfam PF00905 Penicillin binding protein transpeptidase domain 159 490 1.5E-67 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS16075 e1707daaf4d2da7e6a229ad2086af082 495 SUPERFAMILY SSF56601 139 494 3.7E-78 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 SMART SM00347 31 131 9.0E-16 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 Pfam PF12802 MarR family 37 89 2.3E-9 T 16-09-2016 Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 Gene3D G3DSA:1.10.10.10 6 146 4.0E-33 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 PANTHER PTHR33164 4 145 7.3E-53 T 16-09-2016 Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 PANTHER PTHR33164:SF9 4 145 7.3E-53 T 16-09-2016 Spa2297_RS00115 ffd371eb215f9fad2eaad33ac3c09398 153 SUPERFAMILY SSF46785 9 145 4.42E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 PANTHER PTHR20941 2 118 7.2E-35 T 16-09-2016 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 Pfam PF02152 Dihydroneopterin aldolase 5 114 3.4E-35 T 16-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 Gene3D G3DSA:3.30.1130.10 2 118 3.7E-45 T 16-09-2016 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 1.5E-31 T 16-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 115 1.1E-33 T 16-09-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 SMART SM00905 4 116 2.1E-48 T 16-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 Spa2297_RS18200 3d81181f7cf19752748ba9288e067aed 119 SUPERFAMILY SSF55620 2 118 1.28E-36 T 16-09-2016 Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 Gene3D G3DSA:3.20.20.70 2 148 1.3E-31 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 SUPERFAMILY SSF54631 1 143 1.39E-34 T 16-09-2016 Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 SMART SM00116 13 61 4.8E-7 T 16-09-2016 IPR000644 CBS domain Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 SMART SM00116 94 142 3.2E-10 T 16-09-2016 IPR000644 CBS domain Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 Pfam PF00571 CBS domain 90 141 3.3E-15 T 16-09-2016 IPR000644 CBS domain Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 Pfam PF00571 CBS domain 6 60 3.3E-12 T 16-09-2016 IPR000644 CBS domain Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 PIRSF PIRSF036990 4 215 4.9E-70 T 16-09-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 SMART SM00749 150 213 2.4E-7 T 16-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 Pfam PF04972 BON domain 147 205 8.0E-9 T 16-09-2016 IPR007055 BON domain Spa2297_RS01095 cf55fb1f79cd07ccb2adbb57d5643c07 216 PANTHER PTHR11911 5 148 9.0E-32 T 16-09-2016 Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 Pfam PF00294 pfkB family carbohydrate kinase 2 294 3.5E-42 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 237 250 - T 16-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 SUPERFAMILY SSF53613 2 296 1.03E-61 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 PANTHER PTHR10584 2 302 1.8E-77 T 16-09-2016 Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 PANTHER PTHR10584:SF161 2 302 1.8E-77 T 16-09-2016 Spa2297_RS07895 8565eedd1b78e49db3fae97b6de4f5a3 302 Gene3D G3DSA:3.40.1190.20 2 300 1.0E-63 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 181 199 3.1E-8 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 94 110 3.1E-8 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 132 156 3.1E-8 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 301 320 3.1E-8 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 Pfam PF02470 MlaD protein 43 116 2.9E-13 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 296 2.4E-58 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PANTHER PTHR33371 4 318 2.5E-165 T 16-09-2016 Spa2297_RS10185 216ad7803105e5510ea961f1597d10a4 346 PANTHER PTHR33371:SF8 4 318 2.5E-165 T 16-09-2016 Spa2297_RS28530 1a1feb5685683cf710df4939e81994ec 117 SUPERFAMILY SSF51182 15 111 1.43E-13 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS28530 1a1feb5685683cf710df4939e81994ec 117 PANTHER PTHR40943 14 117 1.7E-32 T 16-09-2016 Spa2297_RS28530 1a1feb5685683cf710df4939e81994ec 117 Gene3D G3DSA:2.60.120.10 16 112 2.7E-24 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS28530 1a1feb5685683cf710df4939e81994ec 117 Pfam PF05899 Protein of unknown function (DUF861) 39 110 6.9E-17 T 16-09-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 Spa2297_RS07755 4418693228f7859ad24ba180b96fd51e 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 2.0E-75 T 16-09-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Spa2297_RS07755 4418693228f7859ad24ba180b96fd51e 473 PANTHER PTHR30508 18 473 2.5E-245 T 16-09-2016 Spa2297_RS07755 4418693228f7859ad24ba180b96fd51e 473 PANTHER PTHR30508:SF1 18 473 2.5E-245 T 16-09-2016 Spa2297_RS07755 4418693228f7859ad24ba180b96fd51e 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 2.2E-222 T 16-09-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 Spa2297_RS07755 4418693228f7859ad24ba180b96fd51e 473 SUPERFAMILY SSF101960 39 470 4.05E-142 T 16-09-2016 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 27 257 6.2E-56 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 Gene3D G3DSA:3.40.1180.10 14 258 3.7E-73 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 258 33.663 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 203 220 - T 16-09-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 SUPERFAMILY SSF64005 25 253 8.89E-63 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 PANTHER PTHR10291:SF1 4 258 1.8E-173 T 16-09-2016 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 PANTHER PTHR10291 4 258 1.8E-173 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS16675 335ba1f242f021c6da24caf74cb51fdd 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 34 257 2.8E-63 T 16-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 PANTHER PTHR21581 68 354 2.2E-72 T 16-09-2016 Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 PANTHER PTHR21581:SF1 68 354 2.2E-72 T 16-09-2016 Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 72 310 6.2E-34 T 16-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 SUPERFAMILY SSF56601 75 331 9.75E-43 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 SUPERFAMILY SSF56601 10 35 9.75E-43 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS20465 3d8254da88708d16361f1c7f38c95134 424 Gene3D G3DSA:3.40.710.10 72 332 1.7E-67 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 58 176 9.4E-15 T 16-09-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PANTHER PTHR22600 127 525 1.2E-78 T 16-09-2016 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 Gene3D G3DSA:3.30.379.10 56 165 3.4E-16 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 SUPERFAMILY SSF51445 181 517 5.42E-76 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 Gene3D G3DSA:3.20.20.80 166 520 2.6E-72 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 141 161 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 292 310 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 173 190 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 250 267 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 314 327 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PRINTS PR00738 Glycosyl hydrolase family 20 signature 470 486 3.2E-21 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 SUPERFAMILY SSF55545 51 177 3.66E-17 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 PANTHER PTHR22600:SF0 127 525 1.2E-78 T 16-09-2016 Spa2297_RS20540 212e30e1d8b02cc5dabf489b4fe7f64a 526 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 182 486 3.6E-39 T 16-09-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS28520 e1da7ea8e827a78373be3bc8c267031d 201 PANTHER PTHR31462 2 182 6.9E-15 T 16-09-2016 Spa2297_RS28520 e1da7ea8e827a78373be3bc8c267031d 201 Pfam PF06736 Protein of unknown function (DUF1211) 2 87 1.8E-20 T 16-09-2016 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 361 370 - T 16-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 SUPERFAMILY SSF48264 34 422 2.23E-62 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PANTHER PTHR11712:SF282 1 498 9.9E-148 T 16-09-2016 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 Gene3D G3DSA:1.10.630.10 35 424 1.5E-87 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PANTHER PTHR11712 1 498 9.9E-148 T 16-09-2016 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 182 197 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 216 238 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 165 181 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 119 130 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 312 339 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS06285 1487ee94e7863296d489c5b746748ec8 498 PRINTS PR00359 B-class P450 signature 359 368 4.1E-23 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01520 c123496c073de6685f98473464ea39ac 225 PANTHER PTHR33393:SF4 47 225 8.6E-42 T 16-09-2016 Spa2297_RS01520 c123496c073de6685f98473464ea39ac 225 Pfam PF04203 Sortase family 86 224 7.6E-16 T 16-09-2016 IPR005754 Sortase family Spa2297_RS01520 c123496c073de6685f98473464ea39ac 225 Gene3D G3DSA:2.40.260.10 116 224 3.1E-8 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS01520 c123496c073de6685f98473464ea39ac 225 PANTHER PTHR33393 47 225 8.6E-42 T 16-09-2016 Spa2297_RS01520 c123496c073de6685f98473464ea39ac 225 SUPERFAMILY SSF63817 79 224 8.04E-16 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 SUPERFAMILY SSF48256 7 432 1.96E-160 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 Gene3D G3DSA:1.10.580.10 55 284 4.7E-96 T 16-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 168 181 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 383 397 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 222 237 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 244 272 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 363 379 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PRINTS PR00143 Citrate synthase signature 300 320 3.7E-54 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PANTHER PTHR11739 22 432 3.9E-199 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 426 2.5E-184 T 16-09-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 Pfam PF00285 Citrate synthase, C-terminal domain 49 415 4.4E-134 T 16-09-2016 IPR002020 Citrate synthase GO:0046912 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 ProSitePatterns PS00480 Citrate synthase signature. 307 319 - T 16-09-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 Gene3D G3DSA:1.10.230.10 285 377 1.9E-35 T 16-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain Spa2297_RS11565 f3fea1f5dcef04e78b59c318d317554e 432 PIRSF PIRSF001369 40 432 5.7E-157 T 16-09-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 Gene3D G3DSA:3.30.420.10 21 179 6.4E-45 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 249 314 9.4E-6 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 Pfam PF00929 Exonuclease 25 177 8.0E-24 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 23 179 1.3E-26 T 16-09-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 SMART SM00292 245 323 3.1E-4 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 PANTHER PTHR30231:SF4 8 252 2.1E-57 T 16-09-2016 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 SUPERFAMILY SSF53098 20 182 1.09E-42 T 16-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 Gene3D G3DSA:3.40.50.10190 247 326 1.6E-12 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 PANTHER PTHR30231 8 252 2.1E-57 T 16-09-2016 Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 SUPERFAMILY SSF52113 246 320 2.62E-11 T 16-09-2016 IPR001357 BRCT domain Spa2297_RS07285 ee95e681101c086dab0a78a7337c97ec 330 SMART SM00479 22 186 2.5E-35 T 16-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III Spa2297_RS05080 109120026645159e2923239b741683d9 290 PANTHER PTHR37313 3 290 5.2E-150 T 16-09-2016 Spa2297_RS05080 109120026645159e2923239b741683d9 290 PANTHER PTHR37313:SF3 3 290 5.2E-150 T 16-09-2016 Spa2297_RS05080 109120026645159e2923239b741683d9 290 Pfam PF05949 Bacterial protein of unknown function (DUF881) 153 285 7.3E-39 T 16-09-2016 IPR010273 Protein of unknown function DUF881 Spa2297_RS28835 785f61326af922016cdb11a8a3557c3e 393 SUPERFAMILY SSF103481 37 113 2.75E-5 T 16-09-2016 Spa2297_RS28835 785f61326af922016cdb11a8a3557c3e 393 PANTHER PTHR40761 3 294 1.5E-20 T 16-09-2016 Spa2297_RS28835 785f61326af922016cdb11a8a3557c3e 393 PANTHER PTHR40761:SF1 3 294 1.5E-20 T 16-09-2016 Spa2297_RS15320 1ebf1d5500c12b41ac44cfd0f8db3a13 120 PANTHER PTHR33279 5 120 1.4E-59 T 16-09-2016 Spa2297_RS15320 1ebf1d5500c12b41ac44cfd0f8db3a13 120 SUPERFAMILY SSF75169 3 114 3.2E-20 T 16-09-2016 IPR027396 DsrEFH-like Spa2297_RS15320 1ebf1d5500c12b41ac44cfd0f8db3a13 120 Pfam PF02635 DsrE/DsrF-like family 3 109 9.2E-11 T 16-09-2016 IPR003787 Sulphur relay, DsrE/F-like protein Spa2297_RS15320 1ebf1d5500c12b41ac44cfd0f8db3a13 120 PANTHER PTHR33279:SF2 5 120 1.4E-59 T 16-09-2016 Spa2297_RS15320 1ebf1d5500c12b41ac44cfd0f8db3a13 120 Gene3D G3DSA:3.40.1260.10 3 114 8.4E-18 T 16-09-2016 IPR027396 DsrEFH-like Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 Gene3D G3DSA:3.40.50.300 6 169 3.6E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 Pfam PF01202 Shikimate kinase 13 168 1.3E-43 T 16-09-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PANTHER PTHR21087:SF0 7 169 2.1E-50 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PANTHER PTHR21087 7 169 2.1E-50 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 16-09-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 SUPERFAMILY SSF52540 5 168 1.27E-25 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PRINTS PR01100 Shikimate kinase family signature 31 44 2.7E-17 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PRINTS PR01100 Shikimate kinase family signature 59 67 2.7E-17 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PRINTS PR01100 Shikimate kinase family signature 98 115 2.7E-17 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PRINTS PR01100 Shikimate kinase family signature 7 22 2.7E-17 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 PRINTS PR01100 Shikimate kinase family signature 77 86 2.7E-17 T 16-09-2016 Spa2297_RS05645 44623af9d0cc4669c399ed972d83c205 173 Hamap MF_00109 Shikimate kinase [aroK]. 4 169 26.539 T 16-09-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 Gene3D G3DSA:1.10.260.40 2 60 4.4E-13 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 SUPERFAMILY SSF52540 215 353 4.7E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 SMART SM00530 8 64 1.7E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 Pfam PF05729 NACHT domain 219 349 1.7E-7 T 16-09-2016 Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 Pfam PF13560 Helix-turn-helix domain 4 65 1.7E-14 T 16-09-2016 Spa2297_RS25210 62916e3482ca178193bc1b0a98680c5a 818 SUPERFAMILY SSF47413 4 66 2.28E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 PANTHER PTHR31223 2 174 2.0E-62 T 16-09-2016 Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 PANTHER PTHR31223:SF0 2 174 2.0E-62 T 16-09-2016 Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 Gene3D G3DSA:3.40.50.450 2 174 4.3E-42 T 16-09-2016 Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 Pfam PF03641 Possible lysine decarboxylase 44 171 1.0E-31 T 16-09-2016 IPR031100 LOG family Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 169 1.3E-36 T 16-09-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Spa2297_RS23235 24264ea7560a81a8f78f672752477593 179 SUPERFAMILY SSF102405 1 174 3.51E-41 T 16-09-2016 Spa2297_RS30175 b9b1301c62b1d62ddfde0c00058dce38 426 PANTHER PTHR30483:SF6 42 397 2.3E-67 T 16-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spa2297_RS30175 b9b1301c62b1d62ddfde0c00058dce38 426 SUPERFAMILY SSF53822 56 383 4.04E-53 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS30175 b9b1301c62b1d62ddfde0c00058dce38 426 Gene3D G3DSA:3.40.50.2300 56 251 5.2E-32 T 16-09-2016 Spa2297_RS30175 b9b1301c62b1d62ddfde0c00058dce38 426 PANTHER PTHR30483 42 397 2.3E-67 T 16-09-2016 Spa2297_RS30175 b9b1301c62b1d62ddfde0c00058dce38 426 Pfam PF13458 Periplasmic binding protein 56 397 6.0E-59 T 16-09-2016 IPR028081 Leucine-binding protein domain Spa2297_RS16745 5c1b9652f81ee4422f4d496743b4296a 291 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 207 287 1.2E-13 T 16-09-2016 IPR032030 YscD, cytoplasmic domain Spa2297_RS16745 5c1b9652f81ee4422f4d496743b4296a 291 SUPERFAMILY SSF49879 172 287 1.91E-21 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS16745 5c1b9652f81ee4422f4d496743b4296a 291 SMART SM00240 217 266 9.8E-12 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS16745 5c1b9652f81ee4422f4d496743b4296a 291 Gene3D G3DSA:2.60.200.20 207 287 5.9E-23 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS16745 5c1b9652f81ee4422f4d496743b4296a 291 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 4.1E-42 T 16-09-2016 IPR022128 Protein of unknown function DUF3662 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00412 Epoxide hydrolase signature 261 283 3.7E-11 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00412 Epoxide hydrolase signature 32 50 3.7E-11 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00412 Epoxide hydrolase signature 101 114 3.7E-11 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00412 Epoxide hydrolase signature 52 67 3.7E-11 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 SUPERFAMILY SSF53474 3 285 1.64E-68 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 Pfam PF00561 alpha/beta hydrolase fold 26 178 2.2E-20 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 Gene3D G3DSA:3.40.50.1820 3 284 1.9E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 9.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 9.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 9.4E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PANTHER PTHR10992:SF778 3 286 1.5E-76 T 16-09-2016 Spa2297_RS02820 1dec31d47a40daf8bc3f0999854401e3 286 PANTHER PTHR10992 3 286 1.5E-76 T 16-09-2016 Spa2297_RS31700 9c20ad5e2b764b5aa6fc6b891885658b 378 PANTHER PTHR19328 37 378 6.0E-110 T 16-09-2016 Spa2297_RS31700 9c20ad5e2b764b5aa6fc6b891885658b 378 Gene3D G3DSA:2.120.10.30 37 377 1.0E-94 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS31700 9c20ad5e2b764b5aa6fc6b891885658b 378 SUPERFAMILY SSF50952 47 377 2.48E-30 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS31700 9c20ad5e2b764b5aa6fc6b891885658b 378 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 366 1.6E-44 T 16-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 Pfam PF01494 FAD binding domain 16 178 4.2E-9 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 PANTHER PTHR10617:SF108 1 362 3.6E-109 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 Gene3D G3DSA:3.50.50.60 14 168 2.9E-25 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 SUPERFAMILY SSF51905 15 183 4.5E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 SUPERFAMILY SSF51905 272 360 4.5E-42 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 PANTHER PTHR10617 1 362 3.6E-109 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 Gene3D G3DSA:3.30.9.10 169 319 2.0E-25 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 1.4E-12 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.4E-12 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.4E-12 T 16-09-2016 Spa2297_RS03555 2064ddf5064d554567687a3657bc1f31 410 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 15 310 3.3E-83 T 16-09-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 Spa2297_RS10680 eb088a11eea9aed3df08b49fdeb0cd94 119 Pfam PF04237 YjbR 11 103 1.1E-27 T 16-09-2016 IPR007351 Uncharacterised protein YjbR Spa2297_RS10680 eb088a11eea9aed3df08b49fdeb0cd94 119 SUPERFAMILY SSF142906 3 116 5.36E-40 T 16-09-2016 Spa2297_RS10680 eb088a11eea9aed3df08b49fdeb0cd94 119 PANTHER PTHR35145 3 119 2.5E-41 T 16-09-2016 Spa2297_RS08410 06f0ab6a2c3235f89a8c4e862345a6b3 271 Pfam PF01061 ABC-2 type transporter 46 231 7.5E-12 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 PANTHER PTHR23501:SF69 7 487 1.5E-205 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 Gene3D G3DSA:1.20.1250.20 12 202 4.6E-31 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 434 8.3E-77 T 16-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 2.6E-5 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 2.6E-5 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 172 196 2.6E-5 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 SUPERFAMILY SSF103473 258 484 2.35E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 SUPERFAMILY SSF103473 11 206 2.35E-64 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 92 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 PANTHER PTHR23501 7 487 1.5E-205 T 16-09-2016 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 Pfam PF07690 Major Facilitator Superfamily 26 421 1.9E-48 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS14935 9836922f8b180520bb9365e8a2f82e18 501 Gene3D G3DSA:1.20.1250.20 271 483 2.6E-13 T 16-09-2016 Spa2297_RS10190 2c563ccfcc11e84ba769a077cb7cb773 354 Pfam PF02470 MlaD protein 51 123 4.5E-16 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS10190 2c563ccfcc11e84ba769a077cb7cb773 354 PANTHER PTHR33371 9 326 2.9E-111 T 16-09-2016 Spa2297_RS10190 2c563ccfcc11e84ba769a077cb7cb773 354 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 22 308 3.6E-59 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10190 2c563ccfcc11e84ba769a077cb7cb773 354 PANTHER PTHR33371:SF4 9 326 2.9E-111 T 16-09-2016 Spa2297_RS09355 7de0bff44e7e6c5f573cbb476d3790db 208 PANTHER PTHR36933 6 208 3.0E-42 T 16-09-2016 Spa2297_RS09355 7de0bff44e7e6c5f573cbb476d3790db 208 PANTHER PTHR36933:SF1 6 208 3.0E-42 T 16-09-2016 Spa2297_RS09355 7de0bff44e7e6c5f573cbb476d3790db 208 Pfam PF03713 Domain of unknown function (DUF305) 43 199 8.0E-47 T 16-09-2016 IPR005183 Domain of unknown function DUF305 Spa2297_RS09355 7de0bff44e7e6c5f573cbb476d3790db 208 Gene3D G3DSA:1.20.1260.10 37 202 9.4E-63 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 SUPERFAMILY SSF50475 11 130 1.57E-29 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 PANTHER PTHR35176 10 137 1.2E-44 T 16-09-2016 Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 PANTHER PTHR35176:SF1 10 137 1.2E-44 T 16-09-2016 Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 129 3.5E-28 T 16-09-2016 IPR019920 F420-binding domain, putative Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 Gene3D G3DSA:2.30.110.10 10 131 4.8E-32 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29505 055eb809cff4ba4811ddf5f656913c19 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 3.6E-13 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SUPERFAMILY SSF51126 373 578 2.32E-31 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SUPERFAMILY SSF51126 45 144 2.32E-31 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 PANTHER PTHR36453:SF2 11 625 0.0 T 16-09-2016 Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SMART SM00710 467 489 96.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SMART SM00710 438 466 820.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SMART SM00710 383 405 480.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 SMART SM00710 407 429 62.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 PANTHER PTHR36453 11 625 0.0 T 16-09-2016 Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 Gene3D G3DSA:2.160.20.10 45 151 1.5E-10 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 Gene3D G3DSA:2.160.20.10 372 534 1.5E-13 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS32145 e4f07acf548026b4b35706e296b1f2a7 629 Pfam PF13229 Right handed beta helix region 377 530 2.3E-12 T 16-09-2016 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 461 477 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 130 150 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 172 189 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 479 496 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 308 326 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 201 222 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 330 343 1.4E-47 T 16-09-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 Gene3D G3DSA:3.20.20.80 176 526 1.3E-107 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 47 174 9.4E-22 T 16-09-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 Gene3D G3DSA:3.30.379.10 24 174 5.2E-38 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 SUPERFAMILY SSF55545 40 177 1.83E-38 T 16-09-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PANTHER PTHR22600:SF21 47 532 6.8E-167 T 16-09-2016 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 178 497 2.9E-81 T 16-09-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 PANTHER PTHR22600 47 532 6.8E-167 T 16-09-2016 Spa2297_RS11805 3071d2b0ac01ea87f275adce45c3a68e 533 SUPERFAMILY SSF51445 178 527 1.72E-110 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS29940 3b86b9e71bbf32e1da991ad0116acf6d 268 Pfam PF13437 HlyD family secretion protein 107 193 1.9E-8 T 16-09-2016 Spa2297_RS29940 3b86b9e71bbf32e1da991ad0116acf6d 268 Gene3D G3DSA:2.40.50.100 66 136 2.0E-9 T 16-09-2016 Spa2297_RS29940 3b86b9e71bbf32e1da991ad0116acf6d 268 SUPERFAMILY SSF51230 63 135 1.05E-6 T 16-09-2016 IPR011053 Single hybrid motif Spa2297_RS30910 ff8fa1a61d47f55e239e0129e357de0e 296 Gene3D G3DSA:1.10.3720.10 22 283 1.3E-65 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30910 ff8fa1a61d47f55e239e0129e357de0e 296 PANTHER PTHR32243:SF31 20 296 5.7E-128 T 16-09-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 Spa2297_RS30910 ff8fa1a61d47f55e239e0129e357de0e 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 288 5.6E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30910 ff8fa1a61d47f55e239e0129e357de0e 296 SUPERFAMILY SSF161098 24 296 2.88E-72 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30910 ff8fa1a61d47f55e239e0129e357de0e 296 PANTHER PTHR32243 20 296 5.7E-128 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 SUPERFAMILY SSF56801 39 327 1.57E-106 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 SUPERFAMILY SSF56801 381 640 1.57E-106 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 Pfam PF00501 AMP-binding enzyme 58 511 3.3E-86 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 Gene3D G3DSA:3.40.50.980 53 223 1.6E-30 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 PANTHER PTHR24096 5 640 2.7E-202 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 Gene3D G3DSA:3.40.50.980 378 439 6.3E-29 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 Gene3D G3DSA:3.40.50.980 224 322 6.3E-29 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 PANTHER PTHR24096:SF193 5 640 2.7E-202 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 Gene3D G3DSA:2.30.38.10 440 505 1.6E-14 T 16-09-2016 Spa2297_RS18900 2079a303e8d980191a1004e9bb2541a6 642 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 16-09-2016 IPR020845 AMP-binding, conserved site Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 Gene3D G3DSA:1.20.1260.10 42 275 8.2E-75 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 53 275 3.1E-63 T 16-09-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 PIRSF PIRSF037834 35 275 9.6E-86 T 16-09-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 SUPERFAMILY SSF47240 46 269 1.49E-62 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 PANTHER PTHR30458:SF1 1 275 3.0E-141 T 16-09-2016 Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 Pfam PF05138 Phenylacetic acid catabolic protein 43 275 5.0E-70 T 16-09-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 Spa2297_RS01370 6d3d4e763d608ee8ca9e523ce61a7c30 275 PANTHER PTHR30458 1 275 3.0E-141 T 16-09-2016 Spa2297_RS10465 2fba043f4a1bb70b8bf2dc6407896fd3 209 Pfam PF04203 Sortase family 66 205 1.1E-16 T 16-09-2016 IPR005754 Sortase family Spa2297_RS10465 2fba043f4a1bb70b8bf2dc6407896fd3 209 PANTHER PTHR33393:SF4 33 206 9.1E-49 T 16-09-2016 Spa2297_RS10465 2fba043f4a1bb70b8bf2dc6407896fd3 209 SUPERFAMILY SSF63817 56 206 2.75E-15 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS10465 2fba043f4a1bb70b8bf2dc6407896fd3 209 PANTHER PTHR33393 33 206 9.1E-49 T 16-09-2016 Spa2297_RS10465 2fba043f4a1bb70b8bf2dc6407896fd3 209 Gene3D G3DSA:2.40.260.10 66 187 3.5E-5 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 SUPERFAMILY SSF52540 141 213 2.56E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 SUPERFAMILY SSF52540 272 391 2.56E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 Gene3D G3DSA:3.40.50.300 27 182 2.1E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 SMART SM00487 25 201 9.3E-18 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 Pfam PF04851 Type III restriction enzyme, res subunit 28 179 4.0E-14 T 16-09-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 SUPERFAMILY SSF52540 23 183 7.22E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12595 c1566564c0886a8f5cc538f968c6e5f4 598 Gene3D G3DSA:3.40.50.300 282 393 9.6E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24780 2b9582d40509d0029540ffd1006af2a2 397 PANTHER PTHR10151 16 283 2.3E-28 T 16-09-2016 IPR024873 Ectonucleotide pyrophosphatase/phosphodiesterase family Spa2297_RS24780 2b9582d40509d0029540ffd1006af2a2 397 Gene3D G3DSA:3.40.720.10 33 331 1.6E-45 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS24780 2b9582d40509d0029540ffd1006af2a2 397 SUPERFAMILY SSF53649 54 393 3.93E-62 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS24780 2b9582d40509d0029540ffd1006af2a2 397 PANTHER PTHR10151:SF70 16 283 2.3E-28 T 16-09-2016 Spa2297_RS24780 2b9582d40509d0029540ffd1006af2a2 397 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 59 382 1.8E-45 T 16-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 Gene3D G3DSA:1.10.3300.10 10 192 9.5E-42 T 16-09-2016 IPR023286 ABATE domain Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 Pfam PF07336 Putative stress-induced transcription regulator 17 144 7.0E-21 T 16-09-2016 IPR010852 Putative stress-induced transcription regulator Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 PANTHER PTHR35525:SF3 1 193 5.7E-58 T 16-09-2016 Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 PANTHER PTHR35525 1 193 5.7E-58 T 16-09-2016 Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 Pfam PF11706 CGNR zinc finger 150 192 4.7E-17 T 16-09-2016 IPR021005 Zinc finger, CGNR Spa2297_RS12770 6ddd41d0e7ad4cc2ee6768b4bda0193c 196 SUPERFAMILY SSF160904 11 191 1.57E-37 T 16-09-2016 Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 PANTHER PTHR23417:SF14 60 282 2.5E-65 T 16-09-2016 Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 Gene3D G3DSA:3.40.50.150 110 233 1.1E-9 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 PANTHER PTHR23417 60 282 2.5E-65 T 16-09-2016 Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 67 282 28.291 T 16-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 Pfam PF02390 Putative methyltransferase 108 274 5.4E-50 T 16-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 SUPERFAMILY SSF53335 59 282 1.42E-31 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15635 061e70a927719935e7d6402eefab5c32 295 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 102 282 1.6E-45 T 16-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 Spa2297_RS32155 e98c180b0e72194bfd12926db2f732ec 146 SUPERFAMILY SSF82784 7 143 8.77E-22 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS32155 e98c180b0e72194bfd12926db2f732ec 146 Gene3D G3DSA:3.30.300.20 44 143 4.2E-17 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS32155 e98c180b0e72194bfd12926db2f732ec 146 Pfam PF02566 OsmC-like protein 40 141 1.4E-14 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS32155 e98c180b0e72194bfd12926db2f732ec 146 PANTHER PTHR34352 3 143 2.6E-12 T 16-09-2016 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 SMART SM00882 6 202 2.8E-75 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 Gene3D G3DSA:3.40.810.20 3 210 1.9E-92 T 16-09-2016 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 SUPERFAMILY SSF100950 3 210 6.51E-72 T 16-09-2016 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 PANTHER PTHR13707 2 210 6.4E-127 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 Pfam PF01144 Coenzyme A transferase 7 200 1.9E-43 T 16-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Spa2297_RS27890 aea08879c476bafa3674df6296184c10 226 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 208 9.9E-100 T 16-09-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 PANTHER PTHR23501 10 400 3.5E-198 T 16-09-2016 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 Gene3D G3DSA:1.20.1250.20 16 198 1.3E-26 T 16-09-2016 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 Gene3D G3DSA:1.20.1250.20 216 390 8.7E-13 T 16-09-2016 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 PRINTS PR01035 Tetracycline resistance protein signature 141 163 1.2E-11 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 PRINTS PR01035 Tetracycline resistance protein signature 169 189 1.2E-11 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 PRINTS PR01035 Tetracycline resistance protein signature 27 43 1.2E-11 T 16-09-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 Pfam PF07690 Major Facilitator Superfamily 24 263 1.1E-25 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 SUPERFAMILY SSF103473 14 384 1.7E-51 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS21765 f76a59f3daf3e26b3438ce75d23c20bf 407 PANTHER PTHR23501:SF72 10 400 3.5E-198 T 16-09-2016 Spa2297_RS15060 a132078482bd068b54a8022cbf219c49 244 SUPERFAMILY SSF53448 11 238 7.8E-53 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS15060 a132078482bd068b54a8022cbf219c49 244 PANTHER PTHR22572 12 238 7.7E-89 T 16-09-2016 Spa2297_RS15060 a132078482bd068b54a8022cbf219c49 244 Gene3D G3DSA:3.90.550.10 11 239 8.4E-53 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS15060 a132078482bd068b54a8022cbf219c49 244 PANTHER PTHR22572:SF107 12 238 7.7E-89 T 16-09-2016 Spa2297_RS15060 a132078482bd068b54a8022cbf219c49 244 Pfam PF00483 Nucleotidyl transferase 13 239 1.1E-24 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 SMART SM00347 31 131 5.2E-17 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 PANTHER PTHR33164:SF10 39 155 7.3E-24 T 16-09-2016 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 Pfam PF01047 MarR family 39 96 2.4E-13 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 5.7E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 5.7E-5 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 SUPERFAMILY SSF46785 37 144 2.3E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 PANTHER PTHR33164 39 155 7.3E-24 T 16-09-2016 Spa2297_RS26405 0573f2c42a5416586af8c489168fd35a 161 Gene3D G3DSA:1.10.10.10 25 143 2.5E-26 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1185 22.753 T 16-09-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1183 2.0E-280 T 16-09-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 Gene3D G3DSA:3.40.50.300 2 163 1.4E-87 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 Gene3D G3DSA:3.40.50.300 1032 1180 1.4E-87 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937 2 764 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937 784 957 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937 974 1185 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1176 1.8E-71 T 16-09-2016 IPR003395 RecF/RecN/SMC, N-terminal Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PIRSF PIRSF005719 1 1186 1.7E-258 T 16-09-2016 IPR024704 Structural maintenance of chromosomes protein Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 SMART SM00968 512 623 4.1E-24 T 16-09-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937:SF261 974 1185 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937:SF261 2 764 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 PANTHER PTHR18937:SF261 784 957 0.0 T 16-09-2016 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 SUPERFAMILY SSF75553 494 668 1.7E-25 T 16-09-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 622 1.1E-23 T 16-09-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 SUPERFAMILY SSF52540 2 210 6.59E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23675 45f5cc93fc712604119da663deec1625 1186 SUPERFAMILY SSF52540 1069 1176 6.59E-59 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 SMART SM00220 15 272 3.9E-64 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 16-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 Pfam PF00069 Protein kinase domain 15 264 2.8E-47 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 16-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 SUPERFAMILY SSF56112 9 267 1.24E-69 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 PANTHER PTHR24362:SF247 2 275 8.9E-91 T 16-09-2016 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 Gene3D G3DSA:1.10.510.10 86 266 6.1E-49 T 16-09-2016 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 Gene3D G3DSA:3.30.200.20 8 85 4.7E-23 T 16-09-2016 Spa2297_RS06765 2e8b2a9589392b17d906cb17bc406a50 549 PANTHER PTHR24362 2 275 8.9E-91 T 16-09-2016 Spa2297_RS27460 b42e5d1a50aef5ffbc1dd20fcae2cb42 920 Gene3D G3DSA:3.40.50.300 21 149 5.5E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27460 b42e5d1a50aef5ffbc1dd20fcae2cb42 920 SUPERFAMILY SSF52540 23 223 2.4E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06550 fd9acd3a06320dbf7f90379313f493ea 172 PANTHER PTHR11603 2 164 7.4E-80 T 16-09-2016 Spa2297_RS06550 fd9acd3a06320dbf7f90379313f493ea 172 Pfam PF01202 Shikimate kinase 14 162 3.7E-8 T 16-09-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 Spa2297_RS06550 fd9acd3a06320dbf7f90379313f493ea 172 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 160 5.1E-57 T 16-09-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 Spa2297_RS06550 fd9acd3a06320dbf7f90379313f493ea 172 SUPERFAMILY SSF52540 2 165 9.35E-24 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06550 fd9acd3a06320dbf7f90379313f493ea 172 Gene3D G3DSA:3.40.50.300 3 165 9.3E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS24205 1239740f6e34549b6202e2a8a7d8da6f 354 Gene3D G3DSA:1.10.3720.10 122 346 4.0E-13 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24205 1239740f6e34549b6202e2a8a7d8da6f 354 SUPERFAMILY SSF161098 124 342 1.2E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24205 1239740f6e34549b6202e2a8a7d8da6f 354 PANTHER PTHR30465 19 354 3.5E-200 T 16-09-2016 Spa2297_RS24205 1239740f6e34549b6202e2a8a7d8da6f 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 146 353 5.4E-38 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS24205 1239740f6e34549b6202e2a8a7d8da6f 354 PANTHER PTHR30465:SF53 19 354 3.5E-200 T 16-09-2016 Spa2297_RS17385 e28beefa63b7e23917093d4641437c30 147 SUPERFAMILY SSF48371 15 130 4.03E-8 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS17385 e28beefa63b7e23917093d4641437c30 147 Pfam PF01816 Leucine rich repeat variant 73 98 1.9E-4 T 16-09-2016 IPR004830 Leucine rich repeat variant Spa2297_RS17385 e28beefa63b7e23917093d4641437c30 147 Gene3D G3DSA:1.25.10.10 5 126 8.7E-13 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 Pfam PF13641 Glycosyltransferase like family 2 361 579 1.8E-38 T 16-09-2016 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 Gene3D G3DSA:3.20.20.370 86 287 4.2E-59 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 Pfam PF01522 Polysaccharide deacetylase 89 196 1.4E-32 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 SUPERFAMILY SSF53448 361 612 3.33E-60 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 PANTHER PTHR10859 343 702 1.3E-192 T 16-09-2016 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 PANTHER PTHR10859:SF99 343 702 1.3E-192 T 16-09-2016 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 SUPERFAMILY SSF88713 85 287 2.72E-57 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS12795 97fa4d5676678a4bae9dc5d11e159c5b 734 Gene3D G3DSA:3.90.550.10 361 595 3.1E-47 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS00535 0f95f3c18f8c8ce3ce93e348db2ffff6 177 Gene3D G3DSA:3.40.630.30 2 176 3.2E-51 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS00535 0f95f3c18f8c8ce3ce93e348db2ffff6 177 PANTHER PTHR13256 1 176 3.5E-53 T 16-09-2016 Spa2297_RS00535 0f95f3c18f8c8ce3ce93e348db2ffff6 177 Pfam PF13302 Acetyltransferase (GNAT) domain 8 148 9.7E-37 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS00535 0f95f3c18f8c8ce3ce93e348db2ffff6 177 PANTHER PTHR13256:SF19 1 176 3.5E-53 T 16-09-2016 Spa2297_RS00535 0f95f3c18f8c8ce3ce93e348db2ffff6 177 SUPERFAMILY SSF55729 1 149 1.44E-40 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PANTHER PTHR13789 2 347 1.7E-98 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 Pfam PF01494 FAD binding domain 2 343 4.4E-84 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 Gene3D G3DSA:3.50.50.60 268 350 2.7E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 Gene3D G3DSA:3.50.50.60 2 178 2.7E-60 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 331 5.5E-47 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 PANTHER PTHR13789:SF90 2 347 1.7E-98 T 16-09-2016 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 SUPERFAMILY SSF51905 267 356 2.72E-64 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20585 56fd132fc759df262ba9a1d2236cb906 471 SUPERFAMILY SSF51905 2 173 2.72E-64 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 Gene3D G3DSA:3.60.110.10 238 508 2.0E-35 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 Pfam PF00795 Carbon-nitrogen hydrolase 311 498 1.4E-15 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 PANTHER PTHR23088:SF29 227 522 1.6E-70 T 16-09-2016 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 PANTHER PTHR23088 227 522 1.6E-70 T 16-09-2016 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 SUPERFAMILY SSF56317 240 509 2.35E-41 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 30 514 15.42 T 16-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 Spa2297_RS03370 28761e29dd16555b594de25d3f64f424 537 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 83 477 9.9E-75 T 16-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 16-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 SUPERFAMILY SSF46689 3 70 3.64E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 PANTHER PTHR30328:SF24 1 203 2.2E-62 T 16-09-2016 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 Gene3D G3DSA:1.10.357.10 4 182 5.2E-36 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.9E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.7E-14 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS09285 37990a4e4c29c3bd2d7ce05067f66cfd 221 PANTHER PTHR30328 1 203 2.2E-62 T 16-09-2016 Spa2297_RS23195 cf340044ec4b37e2b7e36d8385f4dc61 286 SUPERFAMILY SSF54637 20 113 4.06E-9 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS23195 cf340044ec4b37e2b7e36d8385f4dc61 286 Pfam PF13622 Thioesterase-like superfamily 39 283 6.0E-41 T 16-09-2016 Spa2297_RS23195 cf340044ec4b37e2b7e36d8385f4dc61 286 SUPERFAMILY SSF54637 140 284 2.93E-9 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683 1118 1412 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683:SF1 1438 1533 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683:SF1 627 944 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SMART SM00382 1054 1217 0.33 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SMART SM00382 720 897 1.4E-4 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SMART SM00382 1349 1514 1.5 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SUPERFAMILY SSF52540 1353 1472 1.08E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 Gene3D G3DSA:3.40.50.300 1041 1205 1.3E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 Gene3D G3DSA:3.40.50.300 712 915 1.8E-29 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SUPERFAMILY SSF52540 710 929 1.04E-30 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 SUPERFAMILY SSF52540 1021 1209 1.74E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683:SF1 1118 1412 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683 1438 1533 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683 627 944 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683 219 609 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 PANTHER PTHR22683:SF1 219 609 1.6E-271 T 16-09-2016 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 Pfam PF01580 FtsK/SpoIIIE family 1036 1211 3.8E-26 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS18930 8d03e4133d21d261c11054fe00c17146 1534 Pfam PF01580 FtsK/SpoIIIE family 697 906 3.6E-32 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS17610 4023c16318dc525cb04d90da5c7fa2cb 313 PANTHER PTHR23024 126 310 9.1E-19 T 16-09-2016 Spa2297_RS17610 4023c16318dc525cb04d90da5c7fa2cb 313 PANTHER PTHR23024 36 101 9.1E-19 T 16-09-2016 Spa2297_RS17610 4023c16318dc525cb04d90da5c7fa2cb 313 SUPERFAMILY SSF53474 13 307 1.43E-37 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17610 4023c16318dc525cb04d90da5c7fa2cb 313 Gene3D G3DSA:3.40.50.1820 22 308 2.7E-42 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS17610 4023c16318dc525cb04d90da5c7fa2cb 313 Pfam PF07859 alpha/beta hydrolase fold 130 290 6.4E-6 T 16-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 Spa2297_RS03475 6137a331980506d06652c335aa5b0d35 216 PANTHER PTHR16557 14 212 9.7E-62 T 16-09-2016 IPR004574 Alkylated DNA repair protein AlkB GO:0006281|GO:0055114 Spa2297_RS03475 6137a331980506d06652c335aa5b0d35 216 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 16 212 7.6E-47 T 16-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like Spa2297_RS03475 6137a331980506d06652c335aa5b0d35 216 Gene3D G3DSA:2.60.120.590 12 212 4.0E-53 T 16-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like Spa2297_RS03475 6137a331980506d06652c335aa5b0d35 216 SUPERFAMILY SSF51197 15 213 2.75E-44 T 16-09-2016 Spa2297_RS23785 fe531df048bc08ba9f2eec8880b3674e 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.4E-52 T 16-09-2016 IPR019592 Protein of unknown function DUF2469 Spa2297_RS24395 99f8698a26a413a1f64e3023183c0d31 387 Pfam PF01594 Domain of unknown function DUF20 14 335 6.0E-81 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS24395 99f8698a26a413a1f64e3023183c0d31 387 PANTHER PTHR21716 3 339 7.5E-63 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS29545 5f4be0aa9f7414ef8b95958058fe2b6f 366 PANTHER PTHR22935 20 345 1.7E-40 T 16-09-2016 Spa2297_RS29545 5f4be0aa9f7414ef8b95958058fe2b6f 366 SUPERFAMILY SSF56601 32 363 3.75E-57 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS29545 5f4be0aa9f7414ef8b95958058fe2b6f 366 Pfam PF00144 Beta-lactamase 40 354 6.0E-50 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS29545 5f4be0aa9f7414ef8b95958058fe2b6f 366 Gene3D G3DSA:3.40.710.10 49 355 1.3E-50 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 22 278 5.4E-50 T 16-09-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 Pfam PF13649 Methyltransferase domain 115 199 8.3E-12 T 16-09-2016 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 PANTHER PTHR18895 6 279 1.4E-91 T 16-09-2016 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 274 1.2E-74 T 16-09-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 Gene3D G3DSA:1.10.8.10 8 83 9.3E-20 T 16-09-2016 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 SUPERFAMILY SSF53335 10 275 3.2E-48 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 43.3 T 16-09-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 PANTHER PTHR18895:SF64 6 279 1.4E-91 T 16-09-2016 Spa2297_RS22640 ceff204aa6c1b61420621b7c3802cdc6 281 Gene3D G3DSA:3.40.50.150 85 278 2.2E-57 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27640 1fc04c9c2791af51ad2fc173945c032f 290 SUPERFAMILY SSF53335 34 165 1.15E-13 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27640 1fc04c9c2791af51ad2fc173945c032f 290 Pfam PF13649 Methyltransferase domain 58 153 4.3E-7 T 16-09-2016 Spa2297_RS27640 1fc04c9c2791af51ad2fc173945c032f 290 Gene3D G3DSA:3.40.50.150 36 170 1.3E-10 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 Gene3D G3DSA:3.40.50.720 380 531 4.5E-29 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 PANTHER PTHR16254 320 545 3.3E-50 T 16-09-2016 Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 Gene3D G3DSA:3.40.50.720 1 136 2.9E-16 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 PANTHER PTHR16254:SF8 320 545 3.3E-50 T 16-09-2016 Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 SUPERFAMILY SSF51735 378 522 1.58E-21 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 Pfam PF02254 TrkA-N domain 80 132 4.4E-8 T 16-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 Pfam PF02254 TrkA-N domain 382 490 3.4E-19 T 16-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spa2297_RS17775 abe675fb4a8a10260d5e91443126d6da 634 SUPERFAMILY SSF51735 81 135 1.26E-9 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 PANTHER PTHR33990 1 160 1.3E-95 T 16-09-2016 Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 PANTHER PTHR33990:SF2 1 160 1.3E-95 T 16-09-2016 Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 SUPERFAMILY SSF54593 6 157 1.25E-50 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 Gene3D G3DSA:3.10.180.10 5 131 2.3E-47 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 PIRSF PIRSF021700 1 159 4.9E-65 T 16-09-2016 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase Spa2297_RS02275 1453640220048ac99c998d9a357fb84f 160 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 119 1.9E-50 T 16-09-2016 IPR028973 3-demethylubiquinone-9 3-methyltransferase Spa2297_RS20920 606e5d92ab9a47d8d51ba6971da88dec 269 Pfam PF13460 NAD(P)H-binding 18 150 7.5E-23 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20920 606e5d92ab9a47d8d51ba6971da88dec 269 PANTHER PTHR14194:SF67 8 240 8.9E-95 T 16-09-2016 Spa2297_RS20920 606e5d92ab9a47d8d51ba6971da88dec 269 SUPERFAMILY SSF51735 13 222 5.83E-42 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS20920 606e5d92ab9a47d8d51ba6971da88dec 269 PANTHER PTHR14194 8 240 8.9E-95 T 16-09-2016 Spa2297_RS20920 606e5d92ab9a47d8d51ba6971da88dec 269 Gene3D G3DSA:3.40.50.720 8 212 2.8E-36 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27905 26ce090e664c82de38c3d23d6d76bd15 332 SUPERFAMILY SSF159774 60 330 5.75E-74 T 16-09-2016 IPR023158 YerB-like domain Spa2297_RS27905 26ce090e664c82de38c3d23d6d76bd15 332 Gene3D G3DSA:3.50.90.10 61 329 2.6E-69 T 16-09-2016 IPR023158 YerB-like domain Spa2297_RS27905 26ce090e664c82de38c3d23d6d76bd15 332 Pfam PF11258 Protein of unknown function (DUF3048) 62 326 1.0E-57 T 16-09-2016 IPR021416 Protein of unknown function DUF3048 Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 6.0E-17 T 16-09-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 PANTHER PTHR20863 4 80 2.1E-14 T 16-09-2016 Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 Gene3D G3DSA:1.10.1200.10 3 81 4.3E-25 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 SUPERFAMILY SSF47336 2 81 7.07E-22 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.07 T 16-09-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 Spa2297_RS10045 882ac7185ebdf991169a50c22fa930b9 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 1.1E-15 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS01590 b81cacfd8c64fd3652d9bc0f45c479c1 227 Pfam PF01955 Adenosylcobinamide amidohydrolase 39 219 1.1E-47 T 16-09-2016 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ Spa2297_RS01590 b81cacfd8c64fd3652d9bc0f45c479c1 227 PANTHER PTHR35336:SF2 24 224 2.3E-60 T 16-09-2016 Spa2297_RS01590 b81cacfd8c64fd3652d9bc0f45c479c1 227 PANTHER PTHR35336 24 224 2.3E-60 T 16-09-2016 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 Gene3D G3DSA:3.40.80.10 225 371 6.9E-42 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 239 358 8.3E-23 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 PANTHER PTHR30417:SF1 95 370 1.3E-67 T 16-09-2016 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 SMART SM00644 229 357 7.0E-40 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 Gene3D G3DSA:1.10.530.10 46 164 2.4E-8 T 16-09-2016 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 SUPERFAMILY SSF53955 47 158 4.69E-7 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 PANTHER PTHR30417 95 370 1.3E-67 T 16-09-2016 Spa2297_RS31255 646c92a021ffd7e5bbc26403b2a181e7 458 SUPERFAMILY SSF55846 228 371 6.15E-40 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS31230 164cbc57b0c60deb401791f3f61f205a 275 SUPERFAMILY SSF81606 72 267 5.75E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31230 164cbc57b0c60deb401791f3f61f205a 275 SMART SM00331 56 269 6.6E-32 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31230 164cbc57b0c60deb401791f3f61f205a 275 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 82 267 1.5E-44 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31230 164cbc57b0c60deb401791f3f61f205a 275 PANTHER PTHR21021:SF19 15 275 1.2E-52 T 16-09-2016 Spa2297_RS31230 164cbc57b0c60deb401791f3f61f205a 275 PANTHER PTHR21021 15 275 1.2E-52 T 16-09-2016 Spa2297_RS04515 df47c4c71073d6dec43d8247735af477 160 PANTHER PTHR24421:SF22 16 152 5.6E-26 T 16-09-2016 Spa2297_RS04515 df47c4c71073d6dec43d8247735af477 160 Pfam PF13581 Histidine kinase-like ATPase domain 11 131 6.9E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04515 df47c4c71073d6dec43d8247735af477 160 SUPERFAMILY SSF55874 30 137 1.37E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04515 df47c4c71073d6dec43d8247735af477 160 Gene3D G3DSA:3.30.565.10 37 138 7.2E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS04515 df47c4c71073d6dec43d8247735af477 160 PANTHER PTHR24421 16 152 5.6E-26 T 16-09-2016 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 15 199 2.3E-50 T 16-09-2016 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 Pfam PF00775 Dioxygenase 44 122 7.6E-7 T 16-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 Gene3D G3DSA:2.60.130.10 12 199 2.5E-56 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 PANTHER PTHR33711:SF2 1 201 2.4E-66 T 16-09-2016 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 SUPERFAMILY SSF49482 12 199 3.01E-42 T 16-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Spa2297_RS27880 884edd12ea2a21bdfbfbe395369b2459 201 PANTHER PTHR33711 1 201 2.4E-66 T 16-09-2016 Spa2297_RS18810 6e3f06009dc0e495fdc9b7371ab49d83 374 Pfam PF01578 Cytochrome C assembly protein 143 356 4.6E-45 T 16-09-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Spa2297_RS18810 6e3f06009dc0e495fdc9b7371ab49d83 374 PANTHER PTHR30071 110 369 2.6E-79 T 16-09-2016 Spa2297_RS18810 6e3f06009dc0e495fdc9b7371ab49d83 374 PANTHER PTHR30071:SF5 110 369 2.6E-79 T 16-09-2016 Spa2297_RS18810 6e3f06009dc0e495fdc9b7371ab49d83 374 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 120 362 1.2E-77 T 16-09-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 SUPERFAMILY SSF53720 13 499 2.09E-162 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 PANTHER PTHR11699:SF97 1 507 0.0 T 16-09-2016 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 Pfam PF00171 Aldehyde dehydrogenase family 35 494 7.9E-162 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 Gene3D G3DSA:3.40.605.10 19 270 2.3E-91 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 PANTHER PTHR11699 1 507 0.0 T 16-09-2016 Spa2297_RS04230 947a39a7b403f852ca3ca0c6487d69c0 507 Gene3D G3DSA:3.40.309.10 271 470 7.2E-59 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS30350 99c4e37daf34ea137c7a7e5e12164f89 295 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 292 3.9E-35 T 16-09-2016 IPR005218 Diacylglycerol/lipid kinase Spa2297_RS30350 99c4e37daf34ea137c7a7e5e12164f89 295 PANTHER PTHR12358 2 293 2.1E-50 T 16-09-2016 Spa2297_RS30350 99c4e37daf34ea137c7a7e5e12164f89 295 SUPERFAMILY SSF111331 1 292 5.01E-62 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS30350 99c4e37daf34ea137c7a7e5e12164f89 295 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 124 4.2E-24 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS30350 99c4e37daf34ea137c7a7e5e12164f89 295 SMART SM00046 3 133 5.1E-4 T 16-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spa2297_RS00575 9c90d1e6cb6415864df0a4b98b16bda7 1209 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 57 1202 0.0 T 16-09-2016 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 Spa2297_RS00575 9c90d1e6cb6415864df0a4b98b16bda7 1209 PANTHER PTHR23304:SF96 59 1208 0.0 T 16-09-2016 Spa2297_RS00575 9c90d1e6cb6415864df0a4b98b16bda7 1209 Pfam PF02514 CobN/Magnesium Chelatase 112 1188 0.0 T 16-09-2016 IPR003672 CobN/magnesium chelatase GO:0009058 Spa2297_RS00575 9c90d1e6cb6415864df0a4b98b16bda7 1209 PANTHER PTHR23304 59 1208 0.0 T 16-09-2016 Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 PANTHER PTHR11935 1 207 3.6E-116 T 16-09-2016 Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 SMART SM00849 24 188 2.4E-40 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 PANTHER PTHR11935:SF82 1 207 3.6E-116 T 16-09-2016 Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 Gene3D G3DSA:3.60.15.10 9 207 6.8E-49 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 SUPERFAMILY SSF56281 11 201 1.44E-50 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS30015 80ad3793ebf9410c59594fd8329c5bf9 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 1.1E-27 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS04700 e01b6557e97d5f0116576abdcdc74c3f 377 SUPERFAMILY SSF56645 18 223 6.41E-29 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS04700 e01b6557e97d5f0116576abdcdc74c3f 377 SUPERFAMILY SSF47203 261 368 4.54E-6 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04700 e01b6557e97d5f0116576abdcdc74c3f 377 Gene3D G3DSA:1.10.540.10 38 93 2.5E-6 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04700 e01b6557e97d5f0116576abdcdc74c3f 377 Gene3D G3DSA:1.20.140.10 216 349 7.1E-4 T 16-09-2016 Spa2297_RS04700 e01b6557e97d5f0116576abdcdc74c3f 377 Gene3D G3DSA:2.40.110.10 128 215 7.7E-14 T 16-09-2016 Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 SUPERFAMILY SSF51735 3 216 1.18E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 201 0.0012 T 16-09-2016 Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 16-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PANTHER PTHR24322:SF330 6 180 1.9E-43 T 16-09-2016 Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.3E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.3E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.3E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.3E-18 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 Pfam PF00106 short chain dehydrogenase 5 189 2.4E-39 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 PANTHER PTHR24322 6 180 1.9E-43 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS23240 63e53cfe0ef772809bd7987461a73e05 229 Gene3D G3DSA:3.40.50.720 5 216 4.2E-52 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 PANTHER PTHR23024:SF24 34 306 2.1E-95 T 16-09-2016 Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 144 159 - T 16-09-2016 IPR019826 Carboxylesterase type B, active site Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 151 163 - T 16-09-2016 IPR033140 Lipase, GDXG, putative serine active site Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 Pfam PF07859 alpha/beta hydrolase fold 79 285 2.3E-77 T 16-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 Gene3D G3DSA:3.40.50.1820 2 309 6.2E-106 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 PANTHER PTHR23024 34 306 2.1E-95 T 16-09-2016 Spa2297_RS26655 b84aacf5121176cc4b4e86f44a81db7f 316 SUPERFAMILY SSF53474 38 307 1.5E-79 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 Pfam PF00579 tRNA synthetases class I (W and Y) 3 287 2.2E-79 T 16-09-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PANTHER PTHR10055:SF10 6 336 4.5E-177 T 16-09-2016 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 6 332 8.2E-107 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 Gene3D G3DSA:1.10.240.10 215 308 2.7E-16 T 16-09-2016 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PANTHER PTHR10055 6 336 4.5E-177 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 SUPERFAMILY SSF52374 6 332 9.38E-99 T 16-09-2016 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 24 - T 16-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 5 333 42.37 T 16-09-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 6.7E-27 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 146 167 6.7E-27 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 6.7E-27 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 199 209 6.7E-27 T 16-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 Spa2297_RS20425 723b8ec03ed1050ed513745eb22ff2fd 337 Gene3D G3DSA:3.40.50.620 4 214 3.6E-90 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 478 498 - T 16-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 PANTHER PTHR11819 282 560 1.8E-179 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 PANTHER PTHR11819:SF159 282 560 1.8E-179 T 16-09-2016 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 Pfam PF00474 Sodium:solute symporter family 308 496 7.8E-12 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 Pfam PF00474 Sodium:solute symporter family 34 198 7.1E-20 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 PANTHER PTHR11819:SF159 1 227 1.8E-179 T 16-09-2016 Spa2297_RS04405 9798ee22e362aad16bcd1eb9b2e5e362 571 PANTHER PTHR11819 1 227 1.8E-179 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS29465 f895c91d833559f09b389aab51ab2795 266 Pfam PF13622 Thioesterase-like superfamily 29 262 3.0E-26 T 16-09-2016 Spa2297_RS29465 f895c91d833559f09b389aab51ab2795 266 SUPERFAMILY SSF54637 131 264 5.14E-7 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 PANTHER PTHR10245:SF20 4 287 7.6E-121 T 16-09-2016 Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 SUPERFAMILY SSF47413 14 73 3.1E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 SMART SM00530 18 73 7.0E-9 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 Gene3D G3DSA:1.10.260.40 13 73 6.9E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 Pfam PF13560 Helix-turn-helix domain 15 74 1.1E-11 T 16-09-2016 Spa2297_RS27235 36565eac8455bdcc7cf6b72f2e85c2ae 287 PANTHER PTHR10245 4 287 7.6E-121 T 16-09-2016 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 SUPERFAMILY SSF51905 15 138 8.26E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 SUPERFAMILY SSF51905 195 325 8.26E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Gene3D G3DSA:3.30.9.10 270 370 6.4E-4 T 16-09-2016 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Gene3D G3DSA:3.30.9.10 139 192 6.4E-4 T 16-09-2016 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Gene3D G3DSA:3.50.50.60 34 135 3.9E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Gene3D G3DSA:3.50.50.60 193 269 3.9E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Gene3D G3DSA:3.50.50.60 373 424 3.9E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 Pfam PF01266 FAD dependent oxidoreductase 45 409 7.1E-46 T 16-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 PANTHER PTHR13847:SF196 4 466 2.9E-151 T 16-09-2016 Spa2297_RS24030 9c88de7582456792067cfdd4c53d276f 475 PANTHER PTHR13847 4 466 2.9E-151 T 16-09-2016 Spa2297_RS23080 f8ed38e389eb1770d01a3d0f01740e0e 167 SUPERFAMILY SSF55874 77 158 2.06E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23080 f8ed38e389eb1770d01a3d0f01740e0e 167 Gene3D G3DSA:3.30.565.10 78 161 5.0E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS23080 f8ed38e389eb1770d01a3d0f01740e0e 167 Pfam PF13581 Histidine kinase-like ATPase domain 47 156 3.2E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 Gene3D G3DSA:3.50.50.60 211 284 1.5E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 Gene3D G3DSA:3.50.50.60 12 103 1.5E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 Gene3D G3DSA:3.50.50.60 154 155 1.5E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 Pfam PF01593 Flavin containing amine oxidoreductase 19 287 2.6E-27 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 PANTHER PTHR10742 10 422 1.5E-120 T 16-09-2016 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 PANTHER PTHR10742:SF275 10 422 1.5E-120 T 16-09-2016 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 SUPERFAMILY SSF51905 11 310 3.21E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30500 76b6c3b6af44c1432cf679f13bc5f479 426 SUPERFAMILY SSF51905 391 422 3.21E-48 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 Gene3D G3DSA:1.10.287.860 160 207 2.8E-14 T 16-09-2016 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 SMART SM00954 49 177 8.9E-20 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 Gene3D G3DSA:3.30.460.10 15 156 2.2E-24 T 16-09-2016 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 PANTHER PTHR41773 7 310 1.3E-13 T 16-09-2016 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 Pfam PF04607 Region found in RelA / SpoT proteins 49 175 2.0E-25 T 16-09-2016 IPR007685 RelA/SpoT GO:0015969 Spa2297_RS07645 a4f3b34464c3870e1cbe055fe196d2ff 352 SUPERFAMILY SSF81301 25 205 4.25E-37 T 16-09-2016 Spa2297_RS00830 1ed4b7950d376c86537c503e49b06a47 298 Gene3D G3DSA:3.40.630.30 151 280 1.2E-13 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS00830 1ed4b7950d376c86537c503e49b06a47 298 SUPERFAMILY SSF55729 151 283 4.95E-15 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS00830 1ed4b7950d376c86537c503e49b06a47 298 Pfam PF00583 Acetyltransferase (GNAT) family 200 273 4.6E-6 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 Pfam PF01048 Phosphorylase superfamily 9 251 6.0E-41 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 SUPERFAMILY SSF53167 8 269 2.82E-82 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 Gene3D G3DSA:3.40.50.1580 6 270 9.2E-83 T 16-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 PANTHER PTHR11904 1 264 8.5E-114 T 16-09-2016 IPR001369 PNP/MTAP phosphorylase Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 7 275 42.111 T 16-09-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 9 254 1.9E-87 T 16-09-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Spa2297_RS13880 3cadebf96f29372a600edc988d650f95 280 PANTHER PTHR11904:SF1 1 264 8.5E-114 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 SUPERFAMILY SSF51905 274 368 1.51E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 SUPERFAMILY SSF51905 6 170 1.51E-46 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 Gene3D G3DSA:3.50.50.60 275 350 9.1E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 Gene3D G3DSA:3.50.50.60 5 175 9.1E-36 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PANTHER PTHR13789:SF174 4 362 1.7E-123 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 Pfam PF01494 FAD binding domain 6 342 1.1E-13 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PANTHER PTHR13789 4 362 1.7E-123 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.1E-19 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 6.1E-19 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 6.1E-19 T 16-09-2016 Spa2297_RS30690 0c760053442ba01c779cb8259b497f5d 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 6.1E-19 T 16-09-2016 Spa2297_RS02980 a6d8613fdfcdba4cf21df88869e506f4 360 SUPERFAMILY SSF53697 39 354 9.03E-43 T 16-09-2016 Spa2297_RS02980 a6d8613fdfcdba4cf21df88869e506f4 360 Gene3D G3DSA:3.40.50.10490 201 337 1.9E-9 T 16-09-2016 Spa2297_RS02980 a6d8613fdfcdba4cf21df88869e506f4 360 PANTHER PTHR10937 43 335 1.3E-22 T 16-09-2016 Spa2297_RS02980 a6d8613fdfcdba4cf21df88869e506f4 360 Pfam PF01380 SIS domain 43 173 4.2E-11 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS02980 a6d8613fdfcdba4cf21df88869e506f4 360 Gene3D G3DSA:3.40.50.10490 37 200 1.7E-19 T 16-09-2016 Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 SUPERFAMILY SSF56300 92 350 3.99E-36 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 Gene3D G3DSA:3.60.21.10 90 355 8.2E-35 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 PANTHER PTHR24032 81 179 5.9E-16 T 16-09-2016 Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 PRINTS PR00114 Serine/threonine phosphatase family signature 94 121 5.7E-5 T 16-09-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 PRINTS PR00114 Serine/threonine phosphatase family signature 131 158 5.7E-5 T 16-09-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 Spa2297_RS16315 2a405d936faf0b39f996ad3810a7c8f3 363 Pfam PF00149 Calcineurin-like phosphoesterase 95 310 5.2E-11 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 PANTHER PTHR41251 2 306 1.6E-77 T 16-09-2016 Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 258 1.6E-85 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 SUPERFAMILY SSF100939 2 256 6.87E-48 T 16-09-2016 IPR016194 SPOC-like, C-terminal domain Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 256 33.216 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 PIRSF PIRSF006493 1 291 1.4E-110 T 16-09-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 SMART SM00559 53 183 3.4E-45 T 16-09-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 Gene3D G3DSA:2.40.290.10 6 148 2.6E-8 T 16-09-2016 IPR016194 SPOC-like, C-terminal domain Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 PANTHER PTHR41251:SF1 2 306 1.6E-77 T 16-09-2016 Spa2297_RS30645 c93462801c94e175c4d55c7546376caf 342 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 173 6.7E-35 T 16-09-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 Pfam PF07690 Major Facilitator Superfamily 210 386 8.5E-10 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 Gene3D G3DSA:1.20.1250.20 204 379 7.9E-17 T 16-09-2016 Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 Gene3D G3DSA:1.20.1250.20 9 172 4.8E-7 T 16-09-2016 Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 SUPERFAMILY SSF103473 5 380 1.18E-30 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 PANTHER PTHR23514 3 408 8.9E-150 T 16-09-2016 Spa2297_RS18530 7aa5f7d4424ac6aa78d3c561c7103519 408 PANTHER PTHR23514:SF13 3 408 8.9E-150 T 16-09-2016 Spa2297_RS13140 5f8306bafcdecdc428b53c20f0e04a09 172 Gene3D G3DSA:2.60.120.10 46 151 5.8E-18 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS13140 5f8306bafcdecdc428b53c20f0e04a09 172 Pfam PF05995 Cysteine dioxygenase type I 19 149 4.9E-23 T 16-09-2016 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|UniPathway: UPA00012 Spa2297_RS13140 5f8306bafcdecdc428b53c20f0e04a09 172 SUPERFAMILY SSF51182 19 149 3.85E-32 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS13140 5f8306bafcdecdc428b53c20f0e04a09 172 PANTHER PTHR12918 12 155 1.6E-32 T 16-09-2016 Spa2297_RS25880 83301780f2ae547e0261fd27f7e2846e 223 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 205 2.5E-40 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS25880 83301780f2ae547e0261fd27f7e2846e 223 Gene3D G3DSA:1.10.3630.10 6 220 2.8E-33 T 16-09-2016 Spa2297_RS17765 69ae313f241c36e750efb6c0fe387c47 280 Pfam PF02104 SURF1 family 23 227 2.1E-20 T 16-09-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 PANTHER PTHR30429 4 275 6.6E-136 T 16-09-2016 IPR004872 Lipoprotein NlpA family Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 Pfam PF03180 NLPA lipoprotein 38 274 4.7E-93 T 16-09-2016 IPR004872 Lipoprotein NlpA family Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 Gene3D G3DSA:3.40.190.10 37 166 9.7E-50 T 16-09-2016 Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 PIRSF PIRSF002854 2 275 1.2E-103 T 16-09-2016 IPR004872 Lipoprotein NlpA family Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 PANTHER PTHR30429:SF0 4 275 6.6E-136 T 16-09-2016 Spa2297_RS05965 837c5b8c4fec64b05a44e2e519107ab9 275 SUPERFAMILY SSF53850 38 275 5.16E-81 T 16-09-2016 Spa2297_RS13675 aedf406b579f536984129c78e59e57dc 499 SUPERFAMILY SSF50998 90 420 1.96E-12 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS13675 aedf406b579f536984129c78e59e57dc 499 Pfam PF13360 PQQ-like domain 114 234 1.6E-8 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS12810 c218509ebb1fe09abbf12d4b6a18f5bf 434 PANTHER PTHR23542:SF1 42 433 1.9E-145 T 16-09-2016 Spa2297_RS12810 c218509ebb1fe09abbf12d4b6a18f5bf 434 Gene3D G3DSA:1.20.1250.20 54 235 8.0E-8 T 16-09-2016 Spa2297_RS12810 c218509ebb1fe09abbf12d4b6a18f5bf 434 PANTHER PTHR23542 42 433 1.9E-145 T 16-09-2016 Spa2297_RS12810 c218509ebb1fe09abbf12d4b6a18f5bf 434 Gene3D G3DSA:1.20.1250.20 247 429 1.7E-6 T 16-09-2016 Spa2297_RS12810 c218509ebb1fe09abbf12d4b6a18f5bf 434 SUPERFAMILY SSF103473 49 431 7.85E-24 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27175 05ce2fb7062a83669b42fcf669669db3 428 PANTHER PTHR11751 49 201 2.6E-15 T 16-09-2016 Spa2297_RS27175 05ce2fb7062a83669b42fcf669669db3 428 SUPERFAMILY SSF53383 13 368 3.73E-35 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS27175 05ce2fb7062a83669b42fcf669669db3 428 Pfam PF00155 Aminotransferase class I and II 68 217 4.4E-9 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS27175 05ce2fb7062a83669b42fcf669669db3 428 Gene3D G3DSA:3.40.640.10 52 275 3.3E-19 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 2.5E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 Gene3D G3DSA:1.10.10.60 5 58 1.9E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 PANTHER PTHR30328:SF7 8 194 5.0E-34 T 16-09-2016 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 SUPERFAMILY SSF48498 84 194 1.03E-16 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 PANTHER PTHR30328 8 194 5.0E-34 T 16-09-2016 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 SUPERFAMILY SSF46689 4 85 4.72E-14 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00005 785fbe4017fb3f3909def952a4eada61 205 Gene3D G3DSA:1.10.357.10 59 188 1.9E-20 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 SUPERFAMILY SSF50998 233 510 1.96E-17 T 16-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 SMART SM00564 467 503 0.17 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 SMART SM00564 320 400 78.0 T 16-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 Pfam PF13360 PQQ-like domain 204 348 1.6E-6 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 Pfam PF13360 PQQ-like domain 381 513 1.3E-7 T 16-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat Spa2297_RS13680 980f3619adf3833b6c84f5c66d0bc0d0 598 Gene3D G3DSA:2.140.10.10 381 544 4.2E-15 T 16-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 Gene3D G3DSA:3.40.190.10 140 263 3.1E-20 T 16-09-2016 Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 SUPERFAMILY SSF53850 38 277 1.47E-34 T 16-09-2016 Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 Pfam PF09084 NMT1/THI5 like 126 277 9.3E-18 T 16-09-2016 IPR015168 SsuA/THI5-like Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 SUPERFAMILY SSF160387 371 453 8.37E-10 T 16-09-2016 Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 PANTHER PTHR30024:SF4 8 408 1.2E-61 T 16-09-2016 Spa2297_RS19290 840e448ca03df0481bdbd5e3b9465c3a 455 PANTHER PTHR30024 8 408 1.2E-61 T 16-09-2016 Spa2297_RS14885 a1d4ba287ffa5bfc3594bc3fa260decd 145 Gene3D G3DSA:3.30.160.200 13 112 9.4E-29 T 16-09-2016 Spa2297_RS14885 a1d4ba287ffa5bfc3594bc3fa260decd 145 SUPERFAMILY SSF75620 14 106 9.02E-14 T 16-09-2016 Spa2297_RS14885 a1d4ba287ffa5bfc3594bc3fa260decd 145 PANTHER PTHR11075 13 140 2.5E-34 T 16-09-2016 Spa2297_RS14885 a1d4ba287ffa5bfc3594bc3fa260decd 145 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 27 43 - T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS14885 a1d4ba287ffa5bfc3594bc3fa260decd 145 Pfam PF00472 RF-1 domain 13 138 1.4E-23 T 16-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 Pfam PF00348 Polyprenyl synthetase 97 330 6.9E-57 T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 SUPERFAMILY SSF48576 78 385 1.04E-70 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 PANTHER PTHR12001:SF23 14 386 1.1E-130 T 16-09-2016 Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 PANTHER PTHR12001 14 386 1.1E-130 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 Gene3D G3DSA:1.10.600.10 50 385 2.0E-81 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS22220 4c540317603ee970b0bba2713703375a 386 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 137 151 - T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.0E-7 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 4.0E-7 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 4.0E-7 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.0E-7 T 16-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 Gene3D G3DSA:3.30.70.1450 147 217 3.4E-11 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 SUPERFAMILY SSF116726 133 216 8.76E-13 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 Gene3D G3DSA:3.40.50.720 1 132 2.8E-30 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 PANTHER PTHR16254 1 159 4.7E-25 T 16-09-2016 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 Pfam PF02254 TrkA-N domain 3 118 2.2E-24 T 16-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 SUPERFAMILY SSF51735 1 145 1.06E-27 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS24895 35cd93557289f063c100eec80c4f0b8c 225 Pfam PF02080 TrkA-C domain 149 216 2.8E-10 T 16-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 PANTHER PTHR26402:SF578 1 225 4.2E-92 T 16-09-2016 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 Gene3D G3DSA:3.40.50.2300 1 115 1.4E-32 T 16-09-2016 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 PANTHER PTHR26402 1 225 4.2E-92 T 16-09-2016 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 Gene3D G3DSA:1.10.10.10 123 224 1.0E-32 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 218 3.4E-22 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 SUPERFAMILY SSF52172 1 164 5.13E-35 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 SMART SM00862 145 220 8.6E-24 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 Pfam PF00072 Response regulator receiver domain 1 106 2.9E-24 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS11885 2c43c833f875a52cf9f3b12367a1b497 241 SMART SM00448 1 107 4.2E-30 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS00410 6fda90292c4385901d4d93127d3539fa 226 Gene3D G3DSA:1.25.10.10 16 191 7.8E-18 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS00410 6fda90292c4385901d4d93127d3539fa 226 SUPERFAMILY SSF48371 16 190 5.76E-16 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS00410 6fda90292c4385901d4d93127d3539fa 226 Pfam PF13646 HEAT repeats 67 127 4.8E-7 T 16-09-2016 Spa2297_RS08440 d78ac702b31789e3a591f5bbb8db6a57 266 PANTHER PTHR13887:SF14 16 262 6.1E-18 T 16-09-2016 Spa2297_RS08440 d78ac702b31789e3a591f5bbb8db6a57 266 PANTHER PTHR13887 16 262 6.1E-18 T 16-09-2016 Spa2297_RS08440 d78ac702b31789e3a591f5bbb8db6a57 266 Pfam PF13462 Thioredoxin 82 261 5.3E-42 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS08440 d78ac702b31789e3a591f5bbb8db6a57 266 Gene3D G3DSA:3.40.30.10 83 262 1.7E-20 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS08440 d78ac702b31789e3a591f5bbb8db6a57 266 SUPERFAMILY SSF52833 80 260 1.55E-15 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 PANTHER PTHR21021 352 662 1.5E-53 T 16-09-2016 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 PANTHER PTHR21021:SF19 352 662 1.5E-53 T 16-09-2016 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Pfam PF08448 PAS fold 106 216 1.8E-12 T 16-09-2016 IPR013656 PAS fold-4 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SMART SM00331 426 653 2.4E-31 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SUPERFAMILY SSF55785 7 85 2.62E-11 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Pfam PF00989 PAS fold 7 84 3.8E-5 T 16-09-2016 IPR013767 PAS fold GO:0006355 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 47 2.1E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 104 221 9.2E-6 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Pfam PF01590 GAF domain 312 397 1.2E-4 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SMART SM00091 4 60 32.0 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SMART SM00091 97 163 0.0074 T 16-09-2016 IPR000014 PAS domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SUPERFAMILY SSF81606 444 652 1.96E-6 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Gene3D G3DSA:3.30.450.20 99 213 5.4E-13 T 16-09-2016 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Gene3D G3DSA:3.30.450.40 226 405 1.1E-27 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 456 653 4.7E-52 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Gene3D G3DSA:3.30.450.20 6 43 1.6E-7 T 16-09-2016 Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SUPERFAMILY SSF55781 294 409 3.92E-11 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 Pfam PF13581 Histidine kinase-like ATPase domain 668 773 7.1E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01925 7d3bcfdd0371d5fbd53cc0f45e334a76 782 SUPERFAMILY SSF55785 102 204 1.45E-10 T 16-09-2016 IPR000014 PAS domain Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 Pfam PF13527 Acetyltransferase (GNAT) domain 17 141 2.5E-32 T 16-09-2016 Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 Gene3D G3DSA:3.30.1050.10 300 408 2.0E-25 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 Gene3D G3DSA:3.40.630.30 23 137 5.0E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 SUPERFAMILY SSF55729 17 314 4.79E-54 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 Gene3D G3DSA:3.40.630.30 138 294 3.3E-13 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 Pfam PF13530 Sterol carrier protein domain 191 417 3.5E-48 T 16-09-2016 IPR025559 Enhanced intracellular survival protein domain Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 PANTHER PTHR37817:SF1 5 420 1.9E-88 T 16-09-2016 Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 PANTHER PTHR37817 5 420 1.9E-88 T 16-09-2016 Spa2297_RS11115 46d185df84462f63c6dc1a7892a45552 420 SUPERFAMILY SSF55718 316 420 2.24E-24 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS13245 d09ec06dbbd02b2850c954987009c764 379 SUPERFAMILY SSF51556 46 364 4.76E-59 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS13245 d09ec06dbbd02b2850c954987009c764 379 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 53 354 8.3E-77 T 16-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 Spa2297_RS13245 d09ec06dbbd02b2850c954987009c764 379 Gene3D G3DSA:3.20.20.140 45 373 7.1E-82 T 16-09-2016 Spa2297_RS13245 d09ec06dbbd02b2850c954987009c764 379 PANTHER PTHR10443:SF26 24 364 1.9E-205 T 16-09-2016 Spa2297_RS13245 d09ec06dbbd02b2850c954987009c764 379 PANTHER PTHR10443 24 364 1.9E-205 T 16-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 PANTHER PTHR23542 2 419 1.8E-148 T 16-09-2016 Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 PANTHER PTHR23542:SF1 2 419 1.8E-148 T 16-09-2016 Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 Gene3D G3DSA:1.20.1250.20 207 381 2.3E-9 T 16-09-2016 Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 Pfam PF07690 Major Facilitator Superfamily 19 331 2.9E-16 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 SUPERFAMILY SSF103473 12 386 5.1E-31 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS06360 30bb98b65bdaef57f96a6f56eb0cedfc 419 Gene3D G3DSA:1.20.1250.20 16 199 1.6E-12 T 16-09-2016 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 Gene3D G3DSA:3.50.50.60 3 168 8.6E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 Gene3D G3DSA:3.50.50.60 280 362 8.6E-10 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 3.4E-5 T 16-09-2016 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 3.4E-5 T 16-09-2016 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 SUPERFAMILY SSF51905 2 163 3.11E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS22370 36d2d334dadccb04ae642121ea8c9b70 421 SUPERFAMILY SSF51905 288 363 3.11E-17 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS27570 2281a2d43edc64df6a03c59c027afd05 465 SUPERFAMILY SSF53300 301 428 6.01E-14 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS27570 2281a2d43edc64df6a03c59c027afd05 465 PANTHER PTHR30634 179 399 7.3E-25 T 16-09-2016 Spa2297_RS27570 2281a2d43edc64df6a03c59c027afd05 465 PANTHER PTHR30634:SF7 179 399 7.3E-25 T 16-09-2016 Spa2297_RS27570 2281a2d43edc64df6a03c59c027afd05 465 Pfam PF05762 VWA domain containing CoxE-like protein 243 448 6.4E-27 T 16-09-2016 IPR008912 Uncharacterised protein family CoxE-like Spa2297_RS25430 221de4c48e38fda385e8c4ecdbe2cd7e 265 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 9 241 3.2E-41 T 16-09-2016 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 PANTHER PTHR23508:SF1 2 430 5.6E-140 T 16-09-2016 Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 Gene3D G3DSA:1.20.1250.20 229 410 6.6E-15 T 16-09-2016 Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 Gene3D G3DSA:1.20.1250.20 3 210 8.2E-20 T 16-09-2016 Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 PANTHER PTHR23508 2 430 5.6E-140 T 16-09-2016 Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 SUPERFAMILY SSF103473 2 410 5.62E-59 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS17310 871534151a352a1e7b28a8c0a7807941 437 Pfam PF07690 Major Facilitator Superfamily 46 375 1.6E-26 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS03665 877178262c8971dff1e7be6a9dbe4c9a 542 Pfam PF13515 Fusaric acid resistance protein-like 306 430 7.2E-21 T 16-09-2016 Spa2297_RS03665 877178262c8971dff1e7be6a9dbe4c9a 542 PANTHER PTHR30509 296 496 3.2E-15 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 486 3.0E-22 T 16-09-2016 IPR025110 AMP-binding enzyme C-terminal domain Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Gene3D G3DSA:3.40.50.980 9 171 1.3E-37 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 SUPERFAMILY SSF56801 7 498 5.76E-147 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Gene3D G3DSA:3.30.300.30 399 495 4.5E-28 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Pfam PF00501 AMP-binding enzyme 14 404 1.7E-97 T 16-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Gene3D G3DSA:2.30.38.10 323 397 1.6E-26 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 PANTHER PTHR24096 8 496 3.9E-271 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 Gene3D G3DSA:3.40.50.980 172 316 8.5E-36 T 16-09-2016 Spa2297_RS02455 2a3c45e7da94e15640003503b21e2889 499 PANTHER PTHR24096:SF229 8 496 3.9E-271 T 16-09-2016 Spa2297_RS16605 36d3d4563625efb56960fbccaf346e30 179 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 59 177 8.7E-42 T 16-09-2016 IPR021949 Domain of unknown function DUF3566. transmembrane Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 Pfam PF00166 Chaperonin 10 Kd subunit 16 102 1.3E-18 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 PRINTS PR00297 10kDa chaperonin signature 90 103 2.5E-8 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 PRINTS PR00297 10kDa chaperonin signature 17 32 2.5E-8 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 PRINTS PR00297 10kDa chaperonin signature 69 81 2.5E-8 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 PRINTS PR00297 10kDa chaperonin signature 43 64 2.5E-8 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 PANTHER PTHR10772 17 113 6.6E-22 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 SUPERFAMILY SSF50129 16 103 2.2E-17 T 16-09-2016 IPR011032 GroES-like Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 Gene3D G3DSA:2.30.33.40 17 102 7.7E-19 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS12390 cc7e98aa9de2e0f489cf3a0bee7a674c 118 SMART SM00883 16 103 6.7E-25 T 16-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spa2297_RS19360 83058eeacb3562fc93d9c73cbc18bede 163 SUPERFAMILY SSF53955 37 159 2.93E-16 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS19360 83058eeacb3562fc93d9c73cbc18bede 163 Pfam PF01464 Transglycosylase SLT domain 88 159 2.1E-8 T 16-09-2016 IPR008258 Transglycosylase SLT domain 1 Spa2297_RS19360 83058eeacb3562fc93d9c73cbc18bede 163 Gene3D G3DSA:1.10.530.10 74 163 1.2E-10 T 16-09-2016 Spa2297_RS08715 ede75b60b6fc8d92ef21e9db0b6e94f3 413 Pfam PF07730 Histidine kinase 190 236 5.3E-6 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS08715 ede75b60b6fc8d92ef21e9db0b6e94f3 413 SUPERFAMILY SSF55874 291 398 1.18E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08715 ede75b60b6fc8d92ef21e9db0b6e94f3 413 Gene3D G3DSA:3.30.565.10 273 399 4.0E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS08715 ede75b60b6fc8d92ef21e9db0b6e94f3 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 399 4.9E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 SUPERFAMILY SSF64288 81 259 7.38E-43 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 93 4.9E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 SMART SM00345 35 93 2.4E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 SUPERFAMILY SSF46785 30 97 1.12E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 Gene3D G3DSA:3.40.1410.10 91 255 2.9E-41 T 16-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 Pfam PF07702 UTRA domain 116 252 4.0E-35 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 3.6E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 3.6E-7 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 Gene3D G3DSA:1.10.10.10 33 90 2.4E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 SMART SM00866 114 253 2.6E-31 T 16-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 PANTHER PTHR11751 33 95 7.0E-13 T 16-09-2016 Spa2297_RS19300 b9e65d3ca35e2f71916fb5e5e6360e01 262 PANTHER PTHR11751 141 165 7.0E-13 T 16-09-2016 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 425 43.432 T 16-09-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 PANTHER PTHR11647 1 427 1.8E-183 T 16-09-2016 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 Gene3D G3DSA:3.20.20.140 65 407 6.1E-104 T 16-09-2016 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 16-09-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 Pfam PF01979 Amidohydrolase family 47 420 1.2E-18 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 PANTHER PTHR11647:SF70 1 427 1.8E-183 T 16-09-2016 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 SUPERFAMILY SSF51338 367 427 1.28E-21 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 SUPERFAMILY SSF51338 1 50 1.28E-21 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 SUPERFAMILY SSF51556 51 361 1.2E-100 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 Gene3D G3DSA:2.30.40.10 3 64 6.3E-19 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS05600 051da0f031250373344aef4b74a155b2 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 5.9E-128 T 16-09-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 Gene3D G3DSA:3.40.50.1400 166 310 1.6E-46 T 16-09-2016 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 PANTHER PTHR11108 7 358 5.8E-90 T 16-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 Pfam PF00762 Ferrochelatase 11 329 1.5E-93 T 16-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 Gene3D G3DSA:3.40.50.1400 8 165 2.8E-40 T 16-09-2016 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 Hamap MF_00323 Ferrochelatase [hemH]. 9 330 30.94 T 16-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 Spa2297_RS24820 0c928972c5f7fe546131bf6ef83c10a2 375 SUPERFAMILY SSF53800 9 335 1.8E-81 T 16-09-2016 Spa2297_RS15805 c3f67fd137b605d9fb633c9e7097ed1b 105 Pfam PF11774 Lsr2 2 104 1.6E-36 T 16-09-2016 IPR024412 Lsr2 Spa2297_RS15805 c3f67fd137b605d9fb633c9e7097ed1b 105 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 101 4.0E-52 T 16-09-2016 IPR024412 Lsr2 Spa2297_RS09955 1d4f174c12a8f6a067b1daf7f0b2aa31 191 Gene3D G3DSA:2.60.60.30 18 183 7.6E-71 T 16-09-2016 Spa2297_RS09955 1d4f174c12a8f6a067b1daf7f0b2aa31 191 Pfam PF02342 TerD domain 1 186 2.9E-80 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS09955 1d4f174c12a8f6a067b1daf7f0b2aa31 191 PANTHER PTHR32097 1 190 9.2E-94 T 16-09-2016 Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 Pfam PF12706 Beta-lactamase superfamily domain 115 314 8.6E-50 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 PANTHER PTHR15032 30 387 7.6E-115 T 16-09-2016 Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 SUPERFAMILY SSF56281 201 350 1.44E-33 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 SUPERFAMILY SSF56281 97 174 1.44E-33 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 PANTHER PTHR15032:SF4 30 387 7.6E-115 T 16-09-2016 Spa2297_RS28235 7063d28fcceaae11af6925727631573a 397 Gene3D G3DSA:3.60.15.10 88 364 4.8E-101 T 16-09-2016 IPR001279 Metallo-beta-lactamase Spa2297_RS18545 53180ed2a57c33e42d90486776960fe4 81 SUPERFAMILY SSF46955 25 74 2.56E-5 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS18545 53180ed2a57c33e42d90486776960fe4 81 Gene3D G3DSA:1.10.10.10 25 73 4.0E-4 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18545 53180ed2a57c33e42d90486776960fe4 81 PANTHER PTHR38431 16 81 9.9E-34 T 16-09-2016 Spa2297_RS18545 53180ed2a57c33e42d90486776960fe4 81 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 25 72 5.8E-21 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS18545 53180ed2a57c33e42d90486776960fe4 81 Pfam PF12728 Helix-turn-helix domain 25 73 6.9E-14 T 16-09-2016 Spa2297_RS05795 7f8bf2832561accdad0d70343ff19410 222 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS05795 7f8bf2832561accdad0d70343ff19410 222 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 1.8E-10 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS28105 0cf515b3c1eee75b6e0dd44194c00c4c 150 SUPERFAMILY SSF55874 40 145 4.02E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28105 0cf515b3c1eee75b6e0dd44194c00c4c 150 Pfam PF13581 Histidine kinase-like ATPase domain 24 122 7.6E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28105 0cf515b3c1eee75b6e0dd44194c00c4c 150 Gene3D G3DSA:3.30.565.10 23 147 4.3E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 Pfam PF01380 SIS domain 152 279 1.3E-26 T 16-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 PANTHER PTHR30514:SF1 21 287 1.1E-67 T 16-09-2016 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 PANTHER PTHR30514 21 287 1.1E-67 T 16-09-2016 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 SUPERFAMILY SSF53697 120 301 1.21E-41 T 16-09-2016 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 SUPERFAMILY SSF46689 21 94 3.4E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 Gene3D G3DSA:3.40.50.10490 120 285 1.1E-39 T 16-09-2016 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 Pfam PF01418 Helix-turn-helix domain, rpiR family 22 94 6.3E-15 T 16-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spa2297_RS00860 b78543492310392f975a150dc3a55cbb 311 Gene3D G3DSA:1.10.10.10 20 95 1.4E-24 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS28790 5e1ccd8690afb5ce2a289d78c5e846a4 144 Pfam PF00296 Luciferase-like monooxygenase 2 83 3.4E-5 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28790 5e1ccd8690afb5ce2a289d78c5e846a4 144 Gene3D G3DSA:3.20.20.30 2 119 9.2E-15 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS28790 5e1ccd8690afb5ce2a289d78c5e846a4 144 SUPERFAMILY SSF51679 1 118 5.1E-15 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS07330 2ab5aaccb6614ac45c76ec34d4aa9ad8 156 Pfam PF03780 Asp23 family, cell envelope-related function 31 142 1.1E-31 T 16-09-2016 IPR005531 Alkaline shock protein Asp23 Spa2297_RS07330 2ab5aaccb6614ac45c76ec34d4aa9ad8 156 PANTHER PTHR34297 21 150 4.4E-46 T 16-09-2016 Spa2297_RS07330 2ab5aaccb6614ac45c76ec34d4aa9ad8 156 PANTHER PTHR34297:SF1 21 150 4.4E-46 T 16-09-2016 Spa2297_RS15540 3d11ffbf0caf93c5275b828db06f33f5 470 SUPERFAMILY SSF52540 40 424 1.08E-34 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15540 3d11ffbf0caf93c5275b828db06f33f5 470 Pfam PF12846 AAA-like domain 69 349 2.7E-15 T 16-09-2016 Spa2297_RS15540 3d11ffbf0caf93c5275b828db06f33f5 470 Gene3D G3DSA:3.40.50.300 251 375 8.9E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS15540 3d11ffbf0caf93c5275b828db06f33f5 470 Gene3D G3DSA:3.40.50.300 73 155 8.9E-13 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 Pfam PF04542 Sigma-70 region 2 20 84 4.6E-18 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 PANTHER PTHR30173:SF16 2 175 2.3E-62 T 16-09-2016 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 173 6.7E-25 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 Gene3D G3DSA:1.10.1740.10 2 112 1.3E-22 T 16-09-2016 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 Gene3D G3DSA:1.10.10.10 113 175 5.3E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 Pfam PF04545 Sigma-70, region 4 123 172 4.1E-13 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 PANTHER PTHR30173 2 175 2.3E-62 T 16-09-2016 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 SUPERFAMILY SSF88946 3 86 3.73E-21 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00660 9323144d8b7384c97871b1570aec4687 178 SUPERFAMILY SSF88659 110 175 4.11E-16 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 244 4.2E-88 T 16-09-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 Gene3D G3DSA:3.40.1010.10 2 110 6.7E-35 T 16-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 16-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 PANTHER PTHR21091:SF17 1 212 4.6E-57 T 16-09-2016 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 SUPERFAMILY SSF53790 2 233 3.93E-62 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 Gene3D G3DSA:3.30.950.10 111 232 4.1E-32 T 16-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 16-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 PANTHER PTHR21091 1 212 4.6E-57 T 16-09-2016 Spa2297_RS00610 488a9c868d751a0166f45e1562d537a0 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 3.9E-40 T 16-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 PANTHER PTHR30589:SF0 1 280 6.7E-120 T 16-09-2016 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 16-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 255 5.5E-65 T 16-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 PANTHER PTHR30589 1 280 6.7E-120 T 16-09-2016 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 15.751 T 16-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 Spa2297_RS08285 ae59e6fa9047d325e0499d3c109dba2f 338 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 12 255 3.9E-41 T 16-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 SUPERFAMILY SSF46785 22 163 2.82E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 SMART SM00347 48 148 1.5E-18 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 Gene3D G3DSA:1.10.10.10 24 162 9.2E-30 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 Pfam PF01047 MarR family 58 112 1.4E-11 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS22340 577ec76e5a3ece911ec58f02a7ee666a 164 PANTHER PTHR33164 3 164 2.5E-23 T 16-09-2016 Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 Pfam PF05576 PS-10 peptidase S37 27 474 0.0 T 16-09-2016 IPR008761 Peptidase S37, tripeptidyl aminopeptidase Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 Gene3D G3DSA:3.40.50.1820 322 418 2.2E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 Gene3D G3DSA:3.40.50.1820 62 252 2.2E-11 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 SUPERFAMILY SSF53474 69 217 5.17E-12 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 SUPERFAMILY SSF53474 337 436 5.17E-12 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11680 74d82788db45f24a9f4e7f8b79000365 474 PANTHER PTHR11010 1 219 1.7E-29 T 16-09-2016 Spa2297_RS09520 41fb3999b22f0a733839d55a18b34c93 334 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 50 322 1.5E-114 T 16-09-2016 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- Spa2297_RS09520 41fb3999b22f0a733839d55a18b34c93 334 Gene3D G3DSA:3.40.50.150 75 178 1.0E-7 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09520 41fb3999b22f0a733839d55a18b34c93 334 SUPERFAMILY SSF53335 55 211 9.65E-13 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09520 41fb3999b22f0a733839d55a18b34c93 334 PANTHER PTHR13184 2 322 1.2E-45 T 16-09-2016 Spa2297_RS09925 18378d2947e2ce320214f1bf6658e88e 270 Gene3D G3DSA:3.40.50.1000 4 99 2.9E-8 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09925 18378d2947e2ce320214f1bf6658e88e 270 Gene3D G3DSA:3.40.50.1000 180 232 2.9E-8 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09925 18378d2947e2ce320214f1bf6658e88e 270 SUPERFAMILY SSF56784 4 244 1.96E-13 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS09925 18378d2947e2ce320214f1bf6658e88e 270 PIRSF PIRSF030802 1 243 9.0E-16 T 16-09-2016 IPR024197 Uncharacterised conserved protein UCP030802 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 PANTHER PTHR12318:SF0 2 282 5.0E-71 T 16-09-2016 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 SUPERFAMILY SSF55811 109 120 1.38E-16 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 SUPERFAMILY SSF55811 28 81 1.38E-16 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 SUPERFAMILY SSF55811 165 231 1.38E-16 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 PANTHER PTHR12318 2 282 5.0E-71 T 16-09-2016 Spa2297_RS17855 30fe92defe5148858b675c39658a7eb8 305 Gene3D G3DSA:3.90.79.10 27 220 1.0E-17 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS03135 4536ef62d299e49a710cc607840df8b5 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 19.575 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS03135 4536ef62d299e49a710cc607840df8b5 124 PANTHER PTHR28259 1 123 7.6E-42 T 16-09-2016 Spa2297_RS03135 4536ef62d299e49a710cc607840df8b5 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 4.6E-25 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS03135 4536ef62d299e49a710cc607840df8b5 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 119 6.4E-30 T 16-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spa2297_RS08450 dec01dc30cb1f4f894e7ba70dd6946b2 198 PANTHER PTHR22946 1 189 2.3E-39 T 16-09-2016 Spa2297_RS08450 dec01dc30cb1f4f894e7ba70dd6946b2 198 SUPERFAMILY SSF53474 3 187 6.4E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08450 dec01dc30cb1f4f894e7ba70dd6946b2 198 Pfam PF01738 Dienelactone hydrolase family 3 187 3.6E-18 T 16-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 Spa2297_RS08450 dec01dc30cb1f4f894e7ba70dd6946b2 198 Gene3D G3DSA:3.40.50.1820 3 187 4.4E-21 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 SMART SM00028 83 116 0.011 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 SMART SM00028 49 82 83.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 Gene3D G3DSA:1.25.40.10 19 116 3.5E-17 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 Pfam PF14559 Tetratricopeptide repeat 25 82 5.8E-6 T 16-09-2016 Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 SUPERFAMILY SSF48452 15 121 3.8E-17 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS08090 9d4cace6e4104356b43befc35f508c6b 126 Pfam PF07719 Tetratricopeptide repeat 83 115 6.1E-7 T 16-09-2016 IPR013105 Tetratricopeptide repeat 2 Spa2297_RS21515 ddba336c3b13d10f608d473d91402b42 136 Pfam PF13581 Histidine kinase-like ATPase domain 16 130 7.7E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS21515 ddba336c3b13d10f608d473d91402b42 136 SUPERFAMILY SSF55874 38 135 3.51E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS20610 1724cf84816727aaeb71d329c953629c 363 Pfam PF01757 Acyltransferase family 27 349 2.4E-29 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS24400 5117997b6d0ce501f69ae27bbc0ea9e4 176 Gene3D G3DSA:2.40.33.20 1 176 6.1E-65 T 16-09-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like Spa2297_RS24400 5117997b6d0ce501f69ae27bbc0ea9e4 176 PANTHER PTHR36930:SF1 18 175 3.9E-37 T 16-09-2016 Spa2297_RS24400 5117997b6d0ce501f69ae27bbc0ea9e4 176 Pfam PF03473 MOSC domain 54 162 1.6E-5 T 16-09-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Spa2297_RS24400 5117997b6d0ce501f69ae27bbc0ea9e4 176 PANTHER PTHR36930 18 175 3.9E-37 T 16-09-2016 Spa2297_RS24400 5117997b6d0ce501f69ae27bbc0ea9e4 176 SUPERFAMILY SSF50800 4 166 1.05E-38 T 16-09-2016 IPR011037 Pyruvate kinase-like, insert domain Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 Pfam PF12146 Serine aminopeptidase, S33 25 251 3.7E-59 T 16-09-2016 IPR022742 Serine aminopeptidase, S33 Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 Gene3D G3DSA:3.40.50.1820 17 264 1.3E-47 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 PANTHER PTHR11614 5 264 4.8E-62 T 16-09-2016 Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 4.3E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 4.3E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.3E-8 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS28390 cf32d2d78530a04d9ff19f8f474e34d8 269 SUPERFAMILY SSF53474 6 266 2.3E-40 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS12050 2ca4ae1d996517eaefda375a751b18bc 243 PANTHER PTHR40267 1 243 4.5E-83 T 16-09-2016 Spa2297_RS12050 2ca4ae1d996517eaefda375a751b18bc 243 Pfam PF01177 Asp/Glu/Hydantoin racemase 55 217 4.1E-9 T 16-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 Pfam PF09423 PhoD-like phosphatase 135 460 3.8E-14 T 16-09-2016 IPR018946 Alkaline phosphatase D-related Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 PANTHER PTHR37031:SF2 6 531 1.8E-149 T 16-09-2016 Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 SUPERFAMILY SSF56300 292 358 1.07E-11 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 SUPERFAMILY SSF56300 391 454 1.07E-11 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 SUPERFAMILY SSF56300 93 256 1.07E-11 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 Gene3D G3DSA:3.60.21.10 124 250 5.0E-5 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 Gene3D G3DSA:3.60.21.10 294 337 5.0E-5 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS09860 ac25136cffff9dfa05e4958f45b3dfa5 546 PANTHER PTHR37031 6 531 1.8E-149 T 16-09-2016 Spa2297_RS16545 de62225f116aaacd3a70f80afaa6c1f6 307 PANTHER PTHR13696 3 290 1.8E-92 T 16-09-2016 Spa2297_RS16545 de62225f116aaacd3a70f80afaa6c1f6 307 Pfam PF13614 AAA domain 30 206 4.0E-57 T 16-09-2016 IPR025669 AAA domain Spa2297_RS16545 de62225f116aaacd3a70f80afaa6c1f6 307 Gene3D G3DSA:3.40.50.300 32 279 3.8E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS16545 de62225f116aaacd3a70f80afaa6c1f6 307 PANTHER PTHR13696:SF52 3 290 1.8E-92 T 16-09-2016 Spa2297_RS16545 de62225f116aaacd3a70f80afaa6c1f6 307 SUPERFAMILY SSF52540 30 278 7.24E-64 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05280 89a7283884c18c5af2d9a21f070e6697 385 SUPERFAMILY SSF53756 5 369 2.48E-58 T 16-09-2016 Spa2297_RS05280 89a7283884c18c5af2d9a21f070e6697 385 Gene3D G3DSA:3.40.50.2000 200 353 7.0E-25 T 16-09-2016 Spa2297_RS05280 89a7283884c18c5af2d9a21f070e6697 385 PANTHER PTHR12526 18 369 8.8E-38 T 16-09-2016 Spa2297_RS05280 89a7283884c18c5af2d9a21f070e6697 385 Pfam PF00534 Glycosyl transferases group 1 200 353 4.6E-25 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS05280 89a7283884c18c5af2d9a21f070e6697 385 Pfam PF13439 Glycosyltransferase Family 4 18 182 3.3E-14 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS16535 220203cfd9270d08153c4efd8848b958 205 Pfam PF00583 Acetyltransferase (GNAT) family 65 139 1.5E-9 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS16535 220203cfd9270d08153c4efd8848b958 205 SUPERFAMILY SSF55729 5 140 3.71E-13 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16535 220203cfd9270d08153c4efd8848b958 205 Gene3D G3DSA:3.40.630.30 42 135 2.4E-11 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30630 e3056e568c89c821632c71d0f80229bb 391 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 177 276 1.1E-13 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS30630 e3056e568c89c821632c71d0f80229bb 391 SUPERFAMILY SSF52266 171 379 1.55E-25 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS30630 e3056e568c89c821632c71d0f80229bb 391 Gene3D G3DSA:3.40.50.1110 158 378 1.3E-9 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS23640 705f28f144cc59bec93ed8e3d40f311d 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 19.072 T 16-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Spa2297_RS23640 705f28f144cc59bec93ed8e3d40f311d 57 Pfam PF01783 Ribosomal L32p protein family 2 56 2.1E-25 T 16-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Spa2297_RS23640 705f28f144cc59bec93ed8e3d40f311d 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 5.2E-26 T 16-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Spa2297_RS23640 705f28f144cc59bec93ed8e3d40f311d 57 SUPERFAMILY SSF57829 2 56 5.19E-21 T 16-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spa2297_RS06950 6aece5821f31b3d672e9db9b0cc8c8de 238 Pfam PF10127 Predicted nucleotidyltransferase 10 218 4.3E-41 T 16-09-2016 IPR018775 Nucleotidyltransferase, predicted Spa2297_RS06950 6aece5821f31b3d672e9db9b0cc8c8de 238 PANTHER PTHR34817 12 230 9.8E-90 T 16-09-2016 Spa2297_RS06950 6aece5821f31b3d672e9db9b0cc8c8de 238 PANTHER PTHR34817:SF2 12 230 9.8E-90 T 16-09-2016 Spa2297_RS09960 63604dbf62e97f5200e87868f2de29b1 191 Gene3D G3DSA:2.60.60.30 18 185 2.0E-75 T 16-09-2016 Spa2297_RS09960 63604dbf62e97f5200e87868f2de29b1 191 PANTHER PTHR32097 2 191 1.5E-97 T 16-09-2016 Spa2297_RS09960 63604dbf62e97f5200e87868f2de29b1 191 Pfam PF02342 TerD domain 3 187 7.7E-87 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS19510 3c6566fc1e86332076b9fdc1c12cf704 414 Pfam PF13520 Amino acid permease 14 386 5.3E-36 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS19510 3c6566fc1e86332076b9fdc1c12cf704 414 PANTHER PTHR11785:SF366 6 414 1.4E-98 T 16-09-2016 Spa2297_RS19510 3c6566fc1e86332076b9fdc1c12cf704 414 PIRSF PIRSF006060 2 407 1.4E-65 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS19510 3c6566fc1e86332076b9fdc1c12cf704 414 PANTHER PTHR11785 6 414 1.4E-98 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS04640 059f8a7663f16797f690d2d0ec4854f2 215 PANTHER PTHR35569 2 215 5.3E-84 T 16-09-2016 Spa2297_RS04640 059f8a7663f16797f690d2d0ec4854f2 215 SUPERFAMILY SSF109604 60 167 1.06E-9 T 16-09-2016 Spa2297_RS04640 059f8a7663f16797f690d2d0ec4854f2 215 PANTHER PTHR35569:SF4 2 215 5.3E-84 T 16-09-2016 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 SUPERFAMILY SSF53850 22 453 2.3E-78 T 16-09-2016 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 Gene3D G3DSA:3.40.190.10 32 155 1.1E-38 T 16-09-2016 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 Gene3D G3DSA:3.40.190.10 336 401 1.1E-38 T 16-09-2016 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 PANTHER PTHR30061:SF1 6 454 8.8E-82 T 16-09-2016 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 Pfam PF01547 Bacterial extracellular solute-binding protein 48 365 7.6E-36 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS22960 df4acf3322f69a0e8447d3600e63a2ad 456 PANTHER PTHR30061 6 454 8.8E-82 T 16-09-2016 Spa2297_RS26800 7a527a7b308cc11718003e54c7c250d5 167 SUPERFAMILY SSF74853 57 152 1.09E-12 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS26800 7a527a7b308cc11718003e54c7c250d5 167 Gene3D G3DSA:2.60.40.1260 31 153 1.0E-9 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS26800 7a527a7b308cc11718003e54c7c250d5 167 Pfam PF00932 Lamin Tail Domain 33 151 4.6E-15 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS30125 08dfdcaf67012612b32b69bfbb407955 300 Pfam PF00583 Acetyltransferase (GNAT) family 221 283 2.4E-7 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS30125 08dfdcaf67012612b32b69bfbb407955 300 SUPERFAMILY SSF55729 171 293 1.13E-14 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS30125 08dfdcaf67012612b32b69bfbb407955 300 Gene3D G3DSA:3.40.630.30 171 292 1.0E-12 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 Gene3D G3DSA:3.90.180.10 5 160 1.8E-6 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 Pfam PF00107 Zinc-binding dehydrogenase 169 269 2.8E-21 T 16-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 SMART SM00829 9 346 0.0029 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 PANTHER PTHR11695 13 49 1.0E-72 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 PANTHER PTHR11695 68 337 1.0E-72 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 SUPERFAMILY SSF51735 136 293 3.94E-32 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 PANTHER PTHR11695:SF5 68 337 1.0E-72 T 16-09-2016 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 SUPERFAMILY SSF50129 4 167 1.41E-11 T 16-09-2016 IPR011032 GroES-like Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 PANTHER PTHR11695:SF5 13 49 1.0E-72 T 16-09-2016 Spa2297_RS01300 013a7115d48947113e7c79de41060a9c 348 Gene3D G3DSA:3.40.50.720 161 269 1.7E-31 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 PANTHER PTHR11911 294 515 1.9E-45 T 16-09-2016 Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 Pfam PF02163 Peptidase family M50 275 325 2.5E-7 T 16-09-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 Pfam PF00571 CBS domain 397 439 0.0036 T 16-09-2016 IPR000644 CBS domain Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 Gene3D G3DSA:3.10.580.10 396 513 4.2E-12 T 16-09-2016 Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 SUPERFAMILY SSF54631 396 513 6.57E-12 T 16-09-2016 Spa2297_RS06410 20d9892823e3bf355722f88ab62e7199 519 PANTHER PTHR11911:SF77 294 515 1.9E-45 T 16-09-2016 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 Pfam PF00005 ABC transporter 45 207 6.2E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 Gene3D G3DSA:3.40.50.300 24 280 2.7E-74 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 SUPERFAMILY SSF52540 25 278 4.38E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 PANTHER PTHR24220:SF535 26 353 1.8E-156 T 16-09-2016 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 SMART SM00382 53 257 7.1E-13 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 320 2.2E-19 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 PANTHER PTHR24220 26 353 1.8E-156 T 16-09-2016 Spa2297_RS23170 f7c6b92795d7481330d72fde5d116dea 365 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 258 348 8.1E-24 T 16-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 SUPERFAMILY SSF53383 2 210 6.07E-35 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 PANTHER PTHR30244:SF13 2 90 5.6E-25 T 16-09-2016 Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 Gene3D G3DSA:3.40.640.10 1 90 2.0E-23 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 Gene3D G3DSA:3.90.1150.10 100 212 3.4E-22 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 2 90 1.5E-28 T 16-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 100 208 2.0E-12 T 16-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spa2297_RS24295 42b7a4ea03c5a8378de8d7f3b3fa2357 220 PANTHER PTHR30244 2 90 5.6E-25 T 16-09-2016 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 Gene3D G3DSA:3.30.110.70 17 118 4.5E-33 T 16-09-2016 IPR002765 Uncharacterised protein family UPF0145 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 PANTHER PTHR34068:SF2 14 121 2.1E-33 T 16-09-2016 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 Pfam PF01906 Putative heavy-metal-binding 16 118 2.0E-34 T 16-09-2016 IPR002765 Uncharacterised protein family UPF0145 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 SUPERFAMILY SSF117782 17 118 1.44E-32 T 16-09-2016 IPR002765 Uncharacterised protein family UPF0145 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 PANTHER PTHR34068 14 121 2.1E-33 T 16-09-2016 Spa2297_RS18140 d090ad568d5c7bc89bcba0f32d1826dc 121 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 16 118 22.693 T 16-09-2016 IPR002765 Uncharacterised protein family UPF0145 Spa2297_RS06185 2c9650b6242bf51eafd56050f3bff2d5 239 Pfam PF13354 Beta-lactamase enzyme family 64 178 4.6E-6 T 16-09-2016 Spa2297_RS06185 2c9650b6242bf51eafd56050f3bff2d5 239 SUPERFAMILY SSF56601 9 213 8.45E-23 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS06185 2c9650b6242bf51eafd56050f3bff2d5 239 Gene3D G3DSA:3.40.710.10 9 50 9.4E-5 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS06185 2c9650b6242bf51eafd56050f3bff2d5 239 Gene3D G3DSA:3.40.710.10 62 225 1.2E-19 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PANTHER PTHR22939 16 265 3.2E-75 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PANTHER PTHR22939 295 359 3.2E-75 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 Gene3D G3DSA:2.40.10.10 144 221 7.6E-30 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 Pfam PF13365 Trypsin-like peptidase domain 150 323 7.5E-30 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 Gene3D G3DSA:2.40.10.10 294 361 2.6E-37 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 Gene3D G3DSA:2.40.10.10 222 255 2.6E-37 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PANTHER PTHR22939:SF79 16 265 3.2E-75 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PANTHER PTHR22939:SF79 295 359 3.2E-75 T 16-09-2016 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PRINTS PR00834 HtrA/DegQ protease family signature 294 311 4.7E-27 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PRINTS PR00834 HtrA/DegQ protease family signature 159 171 4.7E-27 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PRINTS PR00834 HtrA/DegQ protease family signature 316 333 4.7E-27 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 PRINTS PR00834 HtrA/DegQ protease family signature 180 200 4.7E-27 T 16-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 SUPERFAMILY SSF50494 126 253 8.79E-53 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS15400 fef0a27b83a6f6610b122f79d7346549 364 SUPERFAMILY SSF50494 292 360 8.79E-53 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 PANTHER PTHR11374:SF18 3 447 4.9E-213 T 16-09-2016 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 425 1.2E-125 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 302 1.3E-29 T 16-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 PIRSF PIRSF000124 3 444 2.4E-117 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 429 2.6E-26 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 SUPERFAMILY SSF51735 4 196 2.02E-46 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 SUPERFAMILY SSF52413 321 439 3.66E-34 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 191 6.8E-57 T 16-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 SMART SM00984 328 429 2.2E-44 T 16-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 SUPERFAMILY SSF48179 210 306 2.72E-26 T 16-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 PIRSF PIRSF500134 3 447 1.5E-154 T 16-09-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Gene3D G3DSA:3.40.50.720 240 445 3.4E-66 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Gene3D G3DSA:3.40.50.720 4 212 1.6E-69 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 Gene3D G3DSA:1.20.5.100 213 238 1.0E-15 T 16-09-2016 Spa2297_RS13225 0e0fa3bbe127db1073011df0ca4c69c7 447 PANTHER PTHR11374 3 447 4.9E-213 T 16-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Spa2297_RS27925 5de4856b9cdb6322e0f6faeed81bdaca 729 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 117 131 - T 16-09-2016 IPR028871 Blue (type 1) copper protein, binding site Spa2297_RS27925 5de4856b9cdb6322e0f6faeed81bdaca 729 Pfam PF06439 Domain of Unknown Function (DUF1080) 521 727 1.9E-27 T 16-09-2016 IPR010496 Domain of unknown function DUF1080 Spa2297_RS27925 5de4856b9cdb6322e0f6faeed81bdaca 729 SUPERFAMILY SSF49503 33 138 1.0E-12 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS27925 5de4856b9cdb6322e0f6faeed81bdaca 729 Gene3D G3DSA:2.60.40.420 27 138 2.2E-12 T 16-09-2016 IPR008972 Cupredoxin Spa2297_RS27925 5de4856b9cdb6322e0f6faeed81bdaca 729 Gene3D G3DSA:2.60.40.670 262 333 9.1E-4 T 16-09-2016 IPR000601 PKD domain Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Pfam PF01593 Flavin containing amine oxidoreductase 32 459 4.4E-48 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 PANTHER PTHR10742:SF279 21 476 7.2E-234 T 16-09-2016 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 PANTHER PTHR10742 21 476 7.2E-234 T 16-09-2016 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 26 460 2.2E-138 T 16-09-2016 IPR017830 Squalene-associated FAD-dependent desaturase Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 SUPERFAMILY SSF51905 19 328 3.63E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 SUPERFAMILY SSF51905 420 462 3.63E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Gene3D G3DSA:3.50.50.60 229 299 3.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Gene3D G3DSA:3.50.50.60 406 460 3.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Gene3D G3DSA:3.50.50.60 172 188 3.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Gene3D G3DSA:3.50.50.60 24 99 3.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS28165 60f2ef52976dcdb6ff4ed08c5d444a21 478 Gene3D G3DSA:3.50.50.60 370 371 3.3E-31 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 Pfam PF13560 Helix-turn-helix domain 36 90 1.1E-10 T 16-09-2016 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 Gene3D G3DSA:1.10.260.40 34 87 3.7E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 SMART SM00530 38 93 5.3E-5 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 SUPERFAMILY SSF47413 33 87 4.44E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 PANTHER PTHR10245:SF7 6 289 2.3E-32 T 16-09-2016 Spa2297_RS16980 aa0d916f582e5fb2dc7d9e171f58b4bb 291 PANTHER PTHR10245 6 289 2.3E-32 T 16-09-2016 Spa2297_RS02325 993b7dd924965bb65579a0bac81f0ddb 128 Gene3D G3DSA:3.10.450.50 8 123 6.5E-16 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS02325 993b7dd924965bb65579a0bac81f0ddb 128 SUPERFAMILY SSF54427 10 122 2.77E-30 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS02325 993b7dd924965bb65579a0bac81f0ddb 128 Pfam PF12680 SnoaL-like domain 14 116 3.5E-13 T 16-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 PANTHER PTHR21343 1 485 5.0E-202 T 16-09-2016 Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 PANTHER PTHR21343:SF1 1 485 5.0E-202 T 16-09-2016 Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 431 5.0E-43 T 16-09-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 Gene3D G3DSA:3.40.50.300 5 237 2.4E-41 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 Gene3D G3DSA:3.40.50.880 262 444 1.1E-37 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 488 173.883 T 16-09-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 226 9.4E-26 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 SUPERFAMILY SSF52317 274 407 5.02E-35 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 SUPERFAMILY SSF52317 193 239 5.02E-35 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 SUPERFAMILY SSF52540 1 241 3.99E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07385 19222534ba1267da87cfa916b4eb2549 502 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 479 5.1E-135 T 16-09-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Pfam PF13234 rRNA-processing arch domain 495 596 9.2E-6 T 16-09-2016 IPR025696 rRNA-processing arch domain Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SUPERFAMILY SSF52540 46 187 6.86E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SUPERFAMILY SSF52540 265 317 6.86E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SUPERFAMILY SSF52540 359 453 6.86E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Gene3D G3DSA:3.40.50.300 31 217 3.1E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Pfam PF00270 DEAD/DEAH box helicase 38 186 6.8E-19 T 16-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Pfam PF08148 DSHCT (NUC185) domain 759 929 2.0E-36 T 16-09-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SMART SM01142 756 934 1.8E-59 T 16-09-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Gene3D G3DSA:3.40.50.300 362 449 2.0E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 Gene3D G3DSA:3.40.50.300 287 320 2.0E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SMART SM00490 350 439 2.9E-12 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS06310 373ef500cff689bc30904639658ad613 935 SMART SM00487 32 217 1.0E-31 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PANTHER PTHR10992 9 258 2.8E-47 T 16-09-2016 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PANTHER PTHR10992:SF771 9 258 2.8E-47 T 16-09-2016 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 SUPERFAMILY SSF53474 8 256 1.37E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 Gene3D G3DSA:3.40.50.1820 9 256 8.2E-59 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 Pfam PF12697 Alpha/beta hydrolase family 21 249 3.2E-22 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 2.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 2.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 2.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 2.3E-12 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00412 Epoxide hydrolase signature 233 255 1.2E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00412 Epoxide hydrolase signature 87 100 1.2E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS11975 4bdf48e5a43b8bea506f42edc533b948 267 PRINTS PR00412 Epoxide hydrolase signature 44 59 1.2E-7 T 16-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 SMART SM00346 15 105 5.4E-18 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 Pfam PF09339 IclR helix-turn-helix domain 19 66 9.5E-15 T 16-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 SUPERFAMILY SSF55781 73 260 4.71E-43 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 PANTHER PTHR30136 19 271 3.0E-87 T 16-09-2016 Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 PANTHER PTHR30136:SF14 19 271 3.0E-87 T 16-09-2016 Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 SUPERFAMILY SSF46785 19 88 3.37E-17 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 Gene3D G3DSA:3.30.450.40 87 264 1.2E-48 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 Pfam PF01614 Bacterial transcriptional regulator 133 257 6.6E-27 T 16-09-2016 IPR014757 Transcription regulator IclR, C-terminal Spa2297_RS01030 2be8bf1203db70d3d4d37106a5cac874 278 Gene3D G3DSA:1.10.10.10 19 86 2.9E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 SUPERFAMILY SSF46689 21 100 1.75E-15 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 PANTHER PTHR30055 18 205 4.0E-64 T 16-09-2016 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 SUPERFAMILY SSF48498 99 203 4.13E-13 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 Gene3D G3DSA:1.10.357.10 22 204 6.1E-40 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 PANTHER PTHR30055:SF19 18 205 4.0E-64 T 16-09-2016 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 3.4E-10 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 3.4E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS31365 7b199771a6b1629e7f389986ac7e3b6f 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 3.4E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS08755 965f38b4452b8a55dc4d3dd7453fffd0 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 142 1.1E-16 T 16-09-2016 IPR019587 Polyketide cyclase/dehydrase Spa2297_RS08755 965f38b4452b8a55dc4d3dd7453fffd0 146 PANTHER PTHR39683 1 146 5.8E-82 T 16-09-2016 Spa2297_RS08755 965f38b4452b8a55dc4d3dd7453fffd0 146 Gene3D G3DSA:3.30.530.20 4 142 5.8E-18 T 16-09-2016 IPR023393 START-like domain Spa2297_RS08755 965f38b4452b8a55dc4d3dd7453fffd0 146 PANTHER PTHR39683:SF1 1 146 5.8E-82 T 16-09-2016 Spa2297_RS08755 965f38b4452b8a55dc4d3dd7453fffd0 146 SUPERFAMILY SSF55961 1 143 1.24E-31 T 16-09-2016 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 PANTHER PTHR10245:SF20 15 274 4.9E-26 T 16-09-2016 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 Gene3D G3DSA:1.10.260.40 14 65 9.0E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 PANTHER PTHR10245 15 274 4.9E-26 T 16-09-2016 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 Pfam PF13560 Helix-turn-helix domain 17 72 2.4E-10 T 16-09-2016 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 SMART SM00530 21 76 1.3E-4 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS15305 d001d3e66bcdf77baef32ea089a84c1d 279 SUPERFAMILY SSF47413 15 72 3.49E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS30060 c588398287469c26cd264586321869a5 137 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 30 56 3.8E-5 T 16-09-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal Spa2297_RS30060 c588398287469c26cd264586321869a5 137 PANTHER PTHR34075:SF2 23 136 5.9E-32 T 16-09-2016 Spa2297_RS30060 c588398287469c26cd264586321869a5 137 PANTHER PTHR34075 23 136 5.9E-32 T 16-09-2016 Spa2297_RS30060 c588398287469c26cd264586321869a5 137 SUPERFAMILY SSF50249 29 117 5.65E-11 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 SUPERFAMILY SSF51735 120 247 5.69E-30 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 Pfam PF13602 Zinc-binding dehydrogenase 190 326 1.0E-23 T 16-09-2016 Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 PANTHER PTHR11695 15 337 7.0E-87 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 PANTHER PTHR11695:SF294 15 337 7.0E-87 T 16-09-2016 Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 SMART SM00829 10 326 5.2E-15 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 SUPERFAMILY SSF50129 1 157 3.04E-34 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 Gene3D G3DSA:3.40.50.720 155 244 4.1E-14 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 Gene3D G3DSA:3.90.180.10 1 154 1.5E-41 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31470 c81c2cf4f86cd86ef5d6bf11cf2ec060 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 95 3.6E-5 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PRINTS PR00046 Major sigma-70 factor signature 60 73 4.2E-5 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PRINTS PR00046 Major sigma-70 factor signature 146 158 4.2E-5 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PRINTS PR00046 Major sigma-70 factor signature 163 178 4.2E-5 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PRINTS PR00046 Major sigma-70 factor signature 178 189 4.2E-5 T 16-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 Pfam PF04542 Sigma-70 region 2 31 102 6.1E-10 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 Pfam PF04545 Sigma-70, region 4 142 191 7.7E-12 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 Gene3D G3DSA:1.10.1740.10 16 129 2.2E-15 T 16-09-2016 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 190 2.0E-22 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 SUPERFAMILY SSF88659 120 193 2.06E-14 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PANTHER PTHR30173:SF3 2 195 3.4E-79 T 16-09-2016 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 PANTHER PTHR30173 2 195 3.4E-79 T 16-09-2016 Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 Gene3D G3DSA:1.10.10.10 137 193 1.2E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS20115 f1ab740dacebd0ba67f1557b444a8f67 195 SUPERFAMILY SSF88946 12 119 8.24E-16 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS07550 9aa91e7c4e2afc65bb0dd6739d52d031 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 201 5.6E-28 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS07550 9aa91e7c4e2afc65bb0dd6739d52d031 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 144 8.9E-16 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS07550 9aa91e7c4e2afc65bb0dd6739d52d031 211 SUPERFAMILY SSF109854 18 150 2.32E-19 T 16-09-2016 Spa2297_RS07550 9aa91e7c4e2afc65bb0dd6739d52d031 211 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 22 201 3.2E-57 T 16-09-2016 IPR017520 Conserved hypothetical protein CHP03086 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 5 442 35.96 T 16-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Gene3D G3DSA:1.20.1640.10 252 433 2.5E-23 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Gene3D G3DSA:1.20.1640.10 572 738 7.4E-19 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PANTHER PTHR30081:SF1 4 115 5.5E-110 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 SUPERFAMILY SSF82866 570 738 1.83E-28 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PANTHER PTHR30081 141 461 5.5E-110 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 33 426 5.9E-113 T 16-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Pfam PF02355 Protein export membrane protein 554 736 1.5E-62 T 16-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Pfam PF02355 Protein export membrane protein 259 426 7.0E-13 T 16-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 SUPERFAMILY SSF82866 235 429 6.28E-34 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 461 739 25.665 T 16-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PANTHER PTHR30081:SF1 141 461 5.5E-110 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 177 420 1.2E-63 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PANTHER PTHR30081 4 115 5.5E-110 T 16-09-2016 Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PRINTS PR01755 Bacterial translocase SecF protein signature 644 662 1.7E-20 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PRINTS PR01755 Bacterial translocase SecF protein signature 676 691 1.7E-20 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PRINTS PR01755 Bacterial translocase SecF protein signature 487 502 1.7E-20 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 PRINTS PR01755 Bacterial translocase SecF protein signature 596 610 1.7E-20 T 16-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Pfam PF07549 SecD/SecF GG Motif 485 504 2.7E-4 T 16-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 Pfam PF07549 SecD/SecF GG Motif 27 47 2.0E-5 T 16-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Spa2297_RS26115 17fe8bec5388ef5b1efcb31e6a6526f9 768 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 488 728 7.0E-62 T 16-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 1.7E-5 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 SUPERFAMILY SSF46689 25 85 4.67E-8 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 SUPERFAMILY SSF48498 117 211 2.45E-5 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 PANTHER PTHR30055:SF2 13 211 2.3E-36 T 16-09-2016 Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 PANTHER PTHR30055 13 211 2.3E-36 T 16-09-2016 Spa2297_RS04900 be852d981b55bd492e1156775bb597ba 212 Gene3D G3DSA:1.10.357.10 29 211 4.3E-33 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 Pfam PF00171 Aldehyde dehydrogenase family 19 473 1.7E-162 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 Gene3D G3DSA:3.40.309.10 265 453 4.8E-63 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 PANTHER PTHR11699:SF109 1 474 0.0 T 16-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 Gene3D G3DSA:3.40.605.10 8 264 5.2E-90 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 PANTHER PTHR11699 1 474 0.0 T 16-09-2016 Spa2297_RS23895 48168d0f0f1f347d9a32f7f865c7e7d7 479 SUPERFAMILY SSF53720 5 475 1.13E-158 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 PANTHER PTHR21343:SF6 8 244 3.0E-166 T 16-09-2016 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 PANTHER PTHR21343:SF6 293 485 3.0E-166 T 16-09-2016 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 SUPERFAMILY SSF52540 12 204 4.32E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 10 474 42.851 T 16-09-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 PANTHER PTHR21343 8 244 3.0E-166 T 16-09-2016 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Gene3D G3DSA:3.40.50.880 289 484 1.3E-30 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Gene3D G3DSA:3.40.50.300 59 201 1.3E-17 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Gene3D G3DSA:3.40.50.300 11 53 1.4E-5 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 13 200 8.7E-26 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 PANTHER PTHR21343 293 485 3.0E-166 T 16-09-2016 Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 SUPERFAMILY SSF52317 287 482 2.46E-31 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS07400 a2a61f1e39efd16631dc563905b7622b 487 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 291 473 2.8E-24 T 16-09-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 Spa2297_RS16155 105aa3ce4a7200fbf5649bb56ee1cb01 208 Gene3D G3DSA:3.40.50.10440 59 156 3.4E-4 T 16-09-2016 Spa2297_RS06865 229489de413383859dcd339ff590744e 389 SUPERFAMILY SSF51679 14 385 1.06E-85 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06865 229489de413383859dcd339ff590744e 389 PANTHER PTHR30011 14 386 1.1E-87 T 16-09-2016 Spa2297_RS06865 229489de413383859dcd339ff590744e 389 PANTHER PTHR30011:SF18 14 386 1.1E-87 T 16-09-2016 Spa2297_RS06865 229489de413383859dcd339ff590744e 389 Pfam PF00296 Luciferase-like monooxygenase 29 334 1.0E-43 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS06865 229489de413383859dcd339ff590744e 389 Gene3D G3DSA:3.20.20.30 15 385 6.3E-98 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 6.4E-160 T 16-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 Pfam PF02463 RecF/RecN/SMC N terminal domain 12 525 8.0E-18 T 16-09-2016 IPR003395 RecF/RecN/SMC, N-terminal Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 PANTHER PTHR11059 1 572 2.3E-156 T 16-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 Gene3D G3DSA:3.40.50.300 444 531 5.4E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 PIRSF PIRSF003128 1 571 2.5E-156 T 16-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 SUPERFAMILY SSF52540 2 216 1.83E-51 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 SUPERFAMILY SSF52540 4 46 1.15E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 SUPERFAMILY SSF52540 341 520 1.15E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07030 13d755e2d02f529496f9f59e3ad25514 572 Gene3D G3DSA:3.40.50.300 2 205 9.4E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01290 18b29e561120ba6cefcedce63420788a 463 SUPERFAMILY SSF48208 32 447 2.89E-69 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS01290 18b29e561120ba6cefcedce63420788a 463 Pfam PF01204 Trehalase 259 409 1.7E-4 T 16-09-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 Spa2297_RS18660 8ce17fb281577d8a18d5b3cbedf44b7d 397 PANTHER PTHR11118 11 397 5.7E-186 T 16-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Spa2297_RS18660 8ce17fb281577d8a18d5b3cbedf44b7d 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 5.9E-128 T 16-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Spa2297_RS18660 8ce17fb281577d8a18d5b3cbedf44b7d 397 SUPERFAMILY SSF103365 11 397 1.44E-127 T 16-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Spa2297_RS18660 8ce17fb281577d8a18d5b3cbedf44b7d 397 PANTHER PTHR11118:SF3 11 397 5.7E-186 T 16-09-2016 Spa2297_RS06035 6917d7aa38088f8f6967b500ffb7964c 195 Gene3D G3DSA:2.30.110.10 3 110 1.4E-14 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS06035 6917d7aa38088f8f6967b500ffb7964c 195 PANTHER PTHR39336 2 193 2.9E-89 T 16-09-2016 Spa2297_RS06035 6917d7aa38088f8f6967b500ffb7964c 195 PANTHER PTHR39336:SF2 2 193 2.9E-89 T 16-09-2016 Spa2297_RS06035 6917d7aa38088f8f6967b500ffb7964c 195 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 1.4E-11 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS06035 6917d7aa38088f8f6967b500ffb7964c 195 SUPERFAMILY SSF50475 8 114 2.88E-10 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 PANTHER PTHR10314:SF126 19 365 6.7E-200 T 16-09-2016 Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 Gene3D G3DSA:3.40.50.1100 66 162 1.2E-22 T 16-09-2016 Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 SUPERFAMILY SSF53686 42 355 3.14E-69 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 49 334 6.3E-46 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 Gene3D G3DSA:3.40.50.1100 163 354 3.8E-33 T 16-09-2016 Spa2297_RS03430 273741f9aac7c53306aa737b3f696577 374 PANTHER PTHR10314 19 365 6.7E-200 T 16-09-2016 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 39 93 1.1E-22 T 16-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 Gene3D G3DSA:1.20.5.1030 35 92 2.4E-22 T 16-09-2016 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 Hamap MF_00422 Protein translocase subunit SecE [secE]. 35 90 13.301 T 16-09-2016 IPR022943 Preprotein translocase subunit SecE Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 40 88 3.4E-19 T 16-09-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 PANTHER PTHR33910:SF1 23 93 3.8E-19 T 16-09-2016 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 40 68 - T 16-09-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Spa2297_RS19605 2405ed1d5c838ba25ac0c4043a3de8ca 93 PANTHER PTHR33910 23 93 3.8E-19 T 16-09-2016 Spa2297_RS18815 50cf1e5a47dc30d3c1c79f9c13e68978 469 SUPERFAMILY SSF52777 34 212 9.34E-20 T 16-09-2016 Spa2297_RS18815 50cf1e5a47dc30d3c1c79f9c13e68978 469 Pfam PF00668 Condensation domain 66 337 4.6E-10 T 16-09-2016 IPR001242 Condensation domain Spa2297_RS18815 50cf1e5a47dc30d3c1c79f9c13e68978 469 SUPERFAMILY SSF52777 234 463 8.78E-16 T 16-09-2016 Spa2297_RS13770 22b1fbaa29b2605d9463318c2ca601e3 167 SUPERFAMILY SSF55826 30 163 7.46E-37 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS13770 22b1fbaa29b2605d9463318c2ca601e3 167 Gene3D G3DSA:3.90.960.10 29 164 2.8E-46 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS13770 22b1fbaa29b2605d9463318c2ca601e3 167 Pfam PF04073 Aminoacyl-tRNA editing domain 35 152 1.1E-30 T 16-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spa2297_RS13770 22b1fbaa29b2605d9463318c2ca601e3 167 PANTHER PTHR30411 13 166 1.4E-50 T 16-09-2016 Spa2297_RS13770 22b1fbaa29b2605d9463318c2ca601e3 167 PANTHER PTHR30411:SF1 13 166 1.4E-50 T 16-09-2016 Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 171 330 2.5E-9 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 SUPERFAMILY SSF52540 168 393 4.39E-23 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 Gene3D G3DSA:3.40.50.300 167 395 3.6E-22 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 87 392 1.9E-96 T 16-09-2016 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 PANTHER PTHR13696:SF64 109 395 8.8E-84 T 16-09-2016 Spa2297_RS17930 c6844cffb3e32281c98c538bf7349639 403 PANTHER PTHR13696 109 395 8.8E-84 T 16-09-2016 Spa2297_RS11545 56a73d501ede06d985579e188a313fae 63 SUPERFAMILY SSF46955 6 57 1.79E-7 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS11545 56a73d501ede06d985579e188a313fae 63 Gene3D G3DSA:1.10.1660.10 8 47 2.4E-5 T 16-09-2016 Spa2297_RS11545 56a73d501ede06d985579e188a313fae 63 Pfam PF13411 MerR HTH family regulatory protein 9 46 7.9E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS18615 0159f06f68a644f4b4b23693de44a67d 238 Pfam PF14016 Protein of unknown function (DUF4232) 108 229 8.7E-25 T 16-09-2016 IPR025326 Protein of unknown function DUF4232 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 SMART SM00347 51 154 2.6E-20 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 Pfam PF12802 MarR family 56 117 2.3E-11 T 16-09-2016 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 PANTHER PTHR33164 4 178 9.5E-35 T 16-09-2016 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 2.8E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 2.8E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 2.8E-7 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 SUPERFAMILY SSF46785 20 167 7.46E-34 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 Gene3D G3DSA:1.10.10.10 19 168 7.9E-38 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS11935 77912615c9e0604342f22d5f922f2d39 182 PANTHER PTHR33164:SF4 4 178 9.5E-35 T 16-09-2016 Spa2297_RS10885 d82fd8e6ab74ecfe9d29ab211222b410 573 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 482 569 4.0E-10 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS10885 d82fd8e6ab74ecfe9d29ab211222b410 573 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 286 401 3.0E-7 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 SUPERFAMILY SSF47473 2 167 4.49E-27 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 Gene3D G3DSA:1.10.238.10 5 164 6.8E-27 T 16-09-2016 IPR011992 EF-hand domain pair Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 SMART SM00054 60 88 5.1 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 SMART SM00054 9 37 0.02 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 SMART SM00054 103 131 23.0 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 SMART SM00054 137 165 61.0 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 Pfam PF13499 EF-hand domain pair 8 83 1.2E-7 T 16-09-2016 IPR002048 EF-hand domain GO:0005509 Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 ProSitePatterns PS00018 EF-hand calcium-binding domain. 69 81 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 ProSitePatterns PS00018 EF-hand calcium-binding domain. 18 30 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS14390 d363f8f3607e111e78c9214ac5ba55ab 170 ProSitePatterns PS00018 EF-hand calcium-binding domain. 146 158 - T 16-09-2016 IPR018247 EF-Hand 1, calcium-binding site Spa2297_RS08980 e1203ed40b2c105a4bab107c2df628a9 239 Pfam PF13489 Methyltransferase domain 88 199 1.5E-11 T 16-09-2016 Spa2297_RS08980 e1203ed40b2c105a4bab107c2df628a9 239 PANTHER PTHR10108:SF921 12 195 1.6E-46 T 16-09-2016 Spa2297_RS08980 e1203ed40b2c105a4bab107c2df628a9 239 Gene3D G3DSA:3.40.50.150 84 201 1.3E-12 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08980 e1203ed40b2c105a4bab107c2df628a9 239 PANTHER PTHR10108 12 195 1.6E-46 T 16-09-2016 Spa2297_RS08980 e1203ed40b2c105a4bab107c2df628a9 239 SUPERFAMILY SSF53335 84 206 1.91E-16 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS22950 f3b9dcd6de372261655fcafcc7630300 282 PANTHER PTHR32243:SF42 6 282 2.4E-130 T 16-09-2016 Spa2297_RS22950 f3b9dcd6de372261655fcafcc7630300 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 270 1.7E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22950 f3b9dcd6de372261655fcafcc7630300 282 SUPERFAMILY SSF161098 11 278 1.13E-59 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22950 f3b9dcd6de372261655fcafcc7630300 282 Gene3D G3DSA:1.10.3720.10 11 267 9.6E-55 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS22950 f3b9dcd6de372261655fcafcc7630300 282 PANTHER PTHR32243 6 282 2.4E-130 T 16-09-2016 Spa2297_RS30140 f7fc5cb1b821a133e47709c52aa37a7c 305 Gene3D G3DSA:3.40.50.1820 48 298 1.6E-68 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30140 f7fc5cb1b821a133e47709c52aa37a7c 305 SUPERFAMILY SSF53474 49 294 8.73E-47 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30140 f7fc5cb1b821a133e47709c52aa37a7c 305 PANTHER PTHR10272 72 254 5.9E-24 T 16-09-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 Spa2297_RS09620 c7a8bbb66e0423ea756a43bf27064373 196 Pfam PF02591 C4-type zinc ribbon domain 155 188 1.1E-9 T 16-09-2016 IPR003743 C4-type zinc ribbon domain Spa2297_RS09620 c7a8bbb66e0423ea756a43bf27064373 196 PANTHER PTHR39082 2 196 2.1E-57 T 16-09-2016 Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 Gene3D G3DSA:3.30.110.40 345 416 2.4E-20 T 16-09-2016 IPR001455 TusA-like domain Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 349 373 - T 16-09-2016 IPR001455 TusA-like domain Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 Pfam PF01206 Sulfurtransferase TusA 348 415 1.2E-14 T 16-09-2016 IPR001455 TusA-like domain Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 Gene3D G3DSA:3.40.640.10 3 200 2.2E-47 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 Pfam PF00266 Aminotransferase class-V 4 316 3.9E-39 T 16-09-2016 IPR000192 Aminotransferase class V domain Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 PANTHER PTHR11601 2 329 1.4E-84 T 16-09-2016 Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 SUPERFAMILY SSF64307 345 416 1.29E-17 T 16-09-2016 IPR001455 TusA-like domain Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 SUPERFAMILY SSF53383 2 324 7.29E-68 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS08895 d8949a4ba64f2def6aeaab6b3b74ed92 418 Gene3D G3DSA:3.90.1150.10 201 321 3.1E-33 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 SUPERFAMILY SSF46955 1 115 5.13E-27 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 PANTHER PTHR30204:SF4 1 120 1.2E-47 T 16-09-2016 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 Gene3D G3DSA:1.10.1660.10 1 54 8.2E-22 T 16-09-2016 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 SMART SM00422 1 69 8.2E-21 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 Gene3D G3DSA:1.10.1660.10 55 115 4.6E-11 T 16-09-2016 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.0E-17 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-12 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.4E-12 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-12 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS00915 51494c2345b917812b60f5079b01d9ff 126 PANTHER PTHR30204 1 120 1.2E-47 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953:SF28 60 223 2.5E-122 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 Gene3D G3DSA:3.60.21.10 191 526 4.5E-9 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 Pfam PF09423 PhoD-like phosphatase 183 522 6.8E-98 T 16-09-2016 IPR018946 Alkaline phosphatase D-related Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953 60 223 2.5E-122 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953 248 353 2.5E-122 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953 374 407 2.5E-122 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 73 169 7.8E-30 T 16-09-2016 IPR032093 Phospholipase D, N-terminal Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 SUPERFAMILY SSF56300 177 524 6.16E-25 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953:SF28 248 353 2.5E-122 T 16-09-2016 Spa2297_RS29555 95a08334b9009c149a0dea73b365e30e 554 PANTHER PTHR22953:SF28 374 407 2.5E-122 T 16-09-2016 Spa2297_RS30440 200ce6960620c70ecc8c8e0b9409b79e 689 PANTHER PTHR32208 263 489 8.4E-66 T 16-09-2016 Spa2297_RS30440 200ce6960620c70ecc8c8e0b9409b79e 689 PANTHER PTHR32208:SF28 263 489 8.4E-66 T 16-09-2016 Spa2297_RS30440 200ce6960620c70ecc8c8e0b9409b79e 689 Pfam PF09362 Domain of unknown function (DUF1996) 228 454 1.2E-27 T 16-09-2016 IPR018535 Domain of unknown function DUF1996 Spa2297_RS04385 4e7852e60ea68a6a5e4aa315470ab8d4 242 Gene3D G3DSA:3.40.50.880 23 213 7.3E-19 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS04385 4e7852e60ea68a6a5e4aa315470ab8d4 242 PANTHER PTHR21343 5 241 1.4E-104 T 16-09-2016 Spa2297_RS04385 4e7852e60ea68a6a5e4aa315470ab8d4 242 PANTHER PTHR21343:SF9 5 241 1.4E-104 T 16-09-2016 Spa2297_RS04385 4e7852e60ea68a6a5e4aa315470ab8d4 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 202 2.1E-36 T 16-09-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 Spa2297_RS04385 4e7852e60ea68a6a5e4aa315470ab8d4 242 SUPERFAMILY SSF52317 23 214 2.21E-19 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 SUPERFAMILY SSF53807 56 346 1.26E-50 T 16-09-2016 Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 PANTHER PTHR30532 11 348 5.3E-132 T 16-09-2016 Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 PANTHER PTHR30532:SF7 11 348 5.3E-132 T 16-09-2016 Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 Pfam PF01497 Periplasmic binding protein 111 319 4.0E-27 T 16-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 Gene3D G3DSA:3.40.50.1980 54 190 6.8E-28 T 16-09-2016 Spa2297_RS31085 243940b43bf979238cc68a061e7e8842 351 Gene3D G3DSA:3.40.50.1980 191 347 3.3E-18 T 16-09-2016 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 SUPERFAMILY SSF50022 64 156 2.62E-27 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 PRINTS PR00162 Rieske 2Fe-2S subunit signature 117 129 6.4E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 PRINTS PR00162 Rieske 2Fe-2S subunit signature 130 142 6.4E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 108 6.4E-9 T 16-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 Gene3D G3DSA:2.102.10.10 16 156 4.3E-28 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 Pfam PF00355 Rieske [2Fe-2S] domain 66 144 8.4E-17 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS04955 a8034934a3eb7937c0352959f9b15e33 158 PANTHER PTHR10134 66 154 6.0E-22 T 16-09-2016 IPR014349 Rieske iron-sulphur protein GO:0016679|GO:0055114 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 429 450 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 703 720 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 306 325 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 405 429 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 325 341 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PRINTS PR01806 Virulence factor MviN signature 647 666 1.1E-16 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206:SF90 246 257 3.5E-16 T 16-09-2016 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206:SF90 503 735 3.5E-16 T 16-09-2016 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206:SF90 793 805 3.5E-16 T 16-09-2016 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 Pfam PF03023 MviN-like protein 301 778 5.4E-133 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 276 803 4.8E-155 T 16-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206 246 257 3.5E-16 T 16-09-2016 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206 503 735 3.5E-16 T 16-09-2016 Spa2297_RS16505 90fd9cb386b4ef7905aaa7638c92ef19 812 PANTHER PTHR11206 793 805 3.5E-16 T 16-09-2016 Spa2297_RS04235 72a1a787b58224f04c4fcdcd6d5a963e 404 SUPERFAMILY SSF56300 168 400 3.94E-35 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS04235 72a1a787b58224f04c4fcdcd6d5a963e 404 Pfam PF00149 Calcineurin-like phosphoesterase 174 341 2.9E-9 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS04235 72a1a787b58224f04c4fcdcd6d5a963e 404 PANTHER PTHR31302 127 402 1.1E-69 T 16-09-2016 Spa2297_RS04235 72a1a787b58224f04c4fcdcd6d5a963e 404 PANTHER PTHR31302:SF7 127 402 1.1E-69 T 16-09-2016 Spa2297_RS04235 72a1a787b58224f04c4fcdcd6d5a963e 404 Gene3D G3DSA:3.60.21.10 173 352 3.5E-23 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS11895 8af4f9c73585e3680dc9d99dadce67f4 289 PANTHER PTHR12176:SF22 4 257 2.0E-140 T 16-09-2016 Spa2297_RS11895 8af4f9c73585e3680dc9d99dadce67f4 289 SUPERFAMILY SSF53335 17 246 6.88E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS11895 8af4f9c73585e3680dc9d99dadce67f4 289 Gene3D G3DSA:3.40.50.150 24 277 1.8E-65 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS11895 8af4f9c73585e3680dc9d99dadce67f4 289 PANTHER PTHR12176 4 257 2.0E-140 T 16-09-2016 Spa2297_RS16195 4bdd73dff2cea21dddf4fff094949b9c 168 Pfam PF04314 Protein of unknown function (DUF461) 52 147 1.8E-26 T 16-09-2016 IPR007410 DR1885-like metal-binding protein Spa2297_RS16195 4bdd73dff2cea21dddf4fff094949b9c 168 PANTHER PTHR36302:SF1 4 168 1.4E-33 T 16-09-2016 Spa2297_RS16195 4bdd73dff2cea21dddf4fff094949b9c 168 Gene3D G3DSA:3.40.190.10 9 64 8.4E-4 T 16-09-2016 Spa2297_RS16195 4bdd73dff2cea21dddf4fff094949b9c 168 SUPERFAMILY SSF110087 43 154 1.83E-30 T 16-09-2016 IPR007410 DR1885-like metal-binding protein Spa2297_RS16195 4bdd73dff2cea21dddf4fff094949b9c 168 PANTHER PTHR36302 4 168 1.4E-33 T 16-09-2016 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 SUPERFAMILY SSF46894 125 225 5.95E-32 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 Gene3D G3DSA:3.40.50.2300 3 121 6.3E-40 T 16-09-2016 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 PANTHER PTHR26402 2 226 4.9E-177 T 16-09-2016 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 Pfam PF00072 Response regulator receiver domain 4 113 7.3E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 7.0E-28 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 SMART SM00862 148 224 2.2E-30 T 16-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 Gene3D G3DSA:1.10.10.10 128 225 1.1E-36 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 SUPERFAMILY SSF52172 3 124 5.98E-41 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 PANTHER PTHR26402:SF459 2 226 4.9E-177 T 16-09-2016 Spa2297_RS15100 fba9043086e9155f14414dfc33ed9a4b 226 SMART SM00448 2 112 1.2E-44 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS13195 9d00d26b52df3ffa838bcedb9c1385eb 546 PANTHER PTHR33392:SF7 53 544 1.0E-213 T 16-09-2016 Spa2297_RS13195 9d00d26b52df3ffa838bcedb9c1385eb 546 PANTHER PTHR33392 53 544 1.0E-213 T 16-09-2016 Spa2297_RS13195 9d00d26b52df3ffa838bcedb9c1385eb 546 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 415 507 6.3E-13 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS13195 9d00d26b52df3ffa838bcedb9c1385eb 546 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 146 307 1.6E-39 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13195 9d00d26b52df3ffa838bcedb9c1385eb 546 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 146 307 3.0E-41 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS22495 52b49fa429eccd5c05ae70eca58c423e 185 Pfam PF01872 RibD C-terminal domain 3 179 1.0E-24 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS22495 52b49fa429eccd5c05ae70eca58c423e 185 PANTHER PTHR38011:SF2 2 185 6.2E-46 T 16-09-2016 Spa2297_RS22495 52b49fa429eccd5c05ae70eca58c423e 185 PANTHER PTHR38011 2 185 6.2E-46 T 16-09-2016 Spa2297_RS22495 52b49fa429eccd5c05ae70eca58c423e 185 SUPERFAMILY SSF53597 5 184 6.54E-30 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS22495 52b49fa429eccd5c05ae70eca58c423e 185 Gene3D G3DSA:3.40.430.10 11 183 1.8E-28 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 Gene3D G3DSA:2.30.40.10 325 362 7.9E-7 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 PANTHER PTHR11271:SF42 6 362 2.4E-140 T 16-09-2016 Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 SUPERFAMILY SSF51556 52 326 1.13E-60 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 Pfam PF01979 Amidohydrolase family 49 362 7.3E-16 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 PANTHER PTHR11271 6 362 2.4E-140 T 16-09-2016 Spa2297_RS07425 a8e8bebf680000d3faff925f2bcd88a5 363 Gene3D G3DSA:3.20.20.140 53 324 3.7E-62 T 16-09-2016 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 Pfam PF07995 Glucose / Sorbosone dehydrogenase 310 578 9.3E-26 T 16-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 SUPERFAMILY SSF52317 11 239 6.64E-37 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 SUPERFAMILY SSF50952 267 591 2.62E-18 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 SUPERFAMILY SSF50952 656 750 2.62E-18 T 16-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 Gene3D G3DSA:2.120.10.30 243 773 2.9E-86 T 16-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 PANTHER PTHR19328 311 585 1.4E-63 T 16-09-2016 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 PANTHER PTHR19328 629 749 1.4E-63 T 16-09-2016 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 PANTHER PTHR19328 270 289 1.4E-63 T 16-09-2016 Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 Pfam PF06283 Trehalose utilisation 13 235 9.6E-72 T 16-09-2016 IPR029010 ThuA-like domain Spa2297_RS27930 f10e930f2bf7642bb48bea37c983c000 781 Gene3D G3DSA:3.40.50.880 46 242 3.6E-29 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 PANTHER PTHR30007:SF4 1 259 5.2E-72 T 16-09-2016 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 Gene3D G3DSA:3.20.20.140 155 253 2.4E-36 T 16-09-2016 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 Gene3D G3DSA:3.20.20.140 2 85 2.4E-36 T 16-09-2016 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 PANTHER PTHR30007 1 259 5.2E-72 T 16-09-2016 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 Pfam PF02811 PHP domain 4 141 6.6E-8 T 16-09-2016 IPR004013 PHP domain GO:0003824 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 SUPERFAMILY SSF89550 2 80 2.16E-43 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 SUPERFAMILY SSF89550 163 253 2.16E-43 T 16-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Spa2297_RS21775 37ef988a70be5144b00c091dd734079f 285 SMART SM00481 3 67 5.3E-14 T 16-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 Spa2297_RS17520 1a6f546d7214958f53fc38d10bec48a4 291 SUPERFAMILY SSF46894 208 279 4.76E-9 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS17520 1a6f546d7214958f53fc38d10bec48a4 291 Gene3D G3DSA:3.30.870.10 72 203 1.3E-4 T 16-09-2016 Spa2297_RS17520 1a6f546d7214958f53fc38d10bec48a4 291 SMART SM00421 215 272 3.2E-4 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS17520 1a6f546d7214958f53fc38d10bec48a4 291 Gene3D G3DSA:1.10.10.10 214 278 1.2E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS17520 1a6f546d7214958f53fc38d10bec48a4 291 SUPERFAMILY SSF56024 73 205 7.46E-7 T 16-09-2016 Spa2297_RS22375 c7e7bb005f4b396f06ab229ac5460387 387 Gene3D G3DSA:3.90.1720.10 227 345 4.7E-36 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS22375 c7e7bb005f4b396f06ab229ac5460387 387 PANTHER PTHR21666 237 334 2.1E-27 T 16-09-2016 Spa2297_RS22375 c7e7bb005f4b396f06ab229ac5460387 387 PANTHER PTHR21666 29 37 2.1E-27 T 16-09-2016 Spa2297_RS22375 c7e7bb005f4b396f06ab229ac5460387 387 SUPERFAMILY SSF54001 230 345 5.4E-31 T 16-09-2016 Spa2297_RS22375 c7e7bb005f4b396f06ab229ac5460387 387 Pfam PF00877 NlpC/P60 family 246 335 7.6E-20 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS20235 a2b86db1522d6e8cd6fcf899be9aa377 334 Pfam PF03595 Voltage-dependent anion channel 17 311 3.3E-16 T 16-09-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Spa2297_RS26160 d6e8d5382e43e92fa49157afb36bd475 560 Pfam PF13556 PucR C-terminal helix-turn-helix domain 501 558 4.4E-21 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS26160 d6e8d5382e43e92fa49157afb36bd475 560 PANTHER PTHR33744 1 559 2.7E-151 T 16-09-2016 Spa2297_RS26160 d6e8d5382e43e92fa49157afb36bd475 560 PANTHER PTHR33744:SF3 1 559 2.7E-151 T 16-09-2016 Spa2297_RS26160 d6e8d5382e43e92fa49157afb36bd475 560 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 4.7E-26 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 PIRSF PIRSF017388 1 248 1.1E-79 T 16-09-2016 IPR012354 Esterase/lipase GO:0052689 Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 Pfam PF12146 Serine aminopeptidase, S33 19 229 2.7E-20 T 16-09-2016 IPR022742 Serine aminopeptidase, S33 Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 PANTHER PTHR11614 19 267 1.6E-36 T 16-09-2016 Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 Gene3D G3DSA:3.40.50.1820 12 245 8.3E-52 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 SUPERFAMILY SSF53474 17 121 1.91E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS08725 61877d05748c0972032631ca03a8c872 267 SUPERFAMILY SSF53474 174 245 1.91E-36 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26025 dbb999af7615436de4236a6df34c3e5f 178 PANTHER PTHR32097 1 164 1.7E-35 T 16-09-2016 Spa2297_RS26025 dbb999af7615436de4236a6df34c3e5f 178 Pfam PF02342 TerD domain 5 164 3.5E-15 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS26025 dbb999af7615436de4236a6df34c3e5f 178 Gene3D G3DSA:2.60.60.30 7 166 1.3E-37 T 16-09-2016 Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 Pfam PF00092 von Willebrand factor type A domain 169 339 2.1E-24 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 PANTHER PTHR10166:SF15 114 410 3.7E-88 T 16-09-2016 Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 SMART SM00327 166 343 5.8E-29 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 Pfam PF12034 Domain of unknown function (DUF3520) 351 406 1.5E-23 T 16-09-2016 IPR021908 Protein of unknown function DUF3520 Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 SUPERFAMILY SSF53300 163 341 1.7E-37 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 Pfam PF12450 von Willebrand factor 76 139 7.9E-18 T 16-09-2016 IPR022156 Uncharacterised protein YfbK, N-terminal Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 Gene3D G3DSA:3.40.50.410 164 340 3.0E-28 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11520 4bb5740b1dba004da376929848ea701e 515 PANTHER PTHR10166 114 410 3.7E-88 T 16-09-2016 Spa2297_RS14735 d084b02b6555862e62f0591adcd3c813 99 Pfam PF13223 Protein of unknown function (DUF4031) 3 76 1.3E-32 T 16-09-2016 IPR025109 Domain of unknown function DUF4031 Spa2297_RS03145 8ebf806fc2aba3d4b1bc5660581178c1 95 Pfam PF12840 Helix-turn-helix domain 6 71 1.4E-7 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03145 8ebf806fc2aba3d4b1bc5660581178c1 95 PANTHER PTHR33154:SF7 1 94 8.9E-36 T 16-09-2016 Spa2297_RS03145 8ebf806fc2aba3d4b1bc5660581178c1 95 PANTHER PTHR33154 1 94 8.9E-36 T 16-09-2016 Spa2297_RS03145 8ebf806fc2aba3d4b1bc5660581178c1 95 SUPERFAMILY SSF46785 6 91 2.49E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03145 8ebf806fc2aba3d4b1bc5660581178c1 95 Gene3D G3DSA:1.10.10.10 6 93 3.1E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS19335 0acdbaaaa40a365497e51c0db7786cc2 382 Pfam PF02156 Glycosyl hydrolase family 26 215 283 3.2E-6 T 16-09-2016 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 Spa2297_RS19335 0acdbaaaa40a365497e51c0db7786cc2 382 Gene3D G3DSA:3.20.20.80 87 348 7.4E-31 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS19335 0acdbaaaa40a365497e51c0db7786cc2 382 SUPERFAMILY SSF51445 102 352 1.91E-27 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 16-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 PANTHER PTHR11751 22 408 7.3E-154 T 16-09-2016 Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 Gene3D G3DSA:3.40.640.10 52 282 9.6E-77 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 SUPERFAMILY SSF53383 12 405 3.67E-114 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 PANTHER PTHR11751:SF306 22 408 7.3E-154 T 16-09-2016 Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 Pfam PF00155 Aminotransferase class I and II 40 396 1.7E-75 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS19595 d827c5fb22b95812ce032905d8cb4962 408 Gene3D G3DSA:3.90.1150.10 283 405 1.8E-37 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02620 9dd5824bc0eb01c274619b689c7d1a43 129 Pfam PF13581 Histidine kinase-like ATPase domain 16 124 1.1E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02620 9dd5824bc0eb01c274619b689c7d1a43 129 SUPERFAMILY SSF55874 35 121 3.87E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02620 9dd5824bc0eb01c274619b689c7d1a43 129 Gene3D G3DSA:3.30.565.10 40 115 4.5E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11420 d9c2aeb58d0919608627651c9faeb5fd 168 Pfam PF06236 Tyrosinase co-factor MelC1 53 148 2.9E-32 T 16-09-2016 IPR010928 Tyrosinase co-factor MelC1 GO:0005507|GO:0042438 Spa2297_RS10080 1f6c0c18acb4e0c80cc69ca37d42db01 274 PANTHER PTHR37468 1 268 5.9E-91 T 16-09-2016 Spa2297_RS10080 1f6c0c18acb4e0c80cc69ca37d42db01 274 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 11 231 7.8E-32 T 16-09-2016 Spa2297_RS28315 ecb63dbd8c0a16d769a4c318947e9c50 191 Pfam PF01590 GAF domain 40 174 2.3E-12 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28315 ecb63dbd8c0a16d769a4c318947e9c50 191 SMART SM00065 36 185 0.0045 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS28315 ecb63dbd8c0a16d769a4c318947e9c50 191 Gene3D G3DSA:3.30.450.40 36 183 2.1E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS28315 ecb63dbd8c0a16d769a4c318947e9c50 191 SUPERFAMILY SSF55781 38 183 1.88E-20 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS26225 e5b65a47b460b36675170b971591d253 168 Pfam PF03780 Asp23 family, cell envelope-related function 42 152 7.1E-31 T 16-09-2016 IPR005531 Alkaline shock protein Asp23 Spa2297_RS26225 e5b65a47b460b36675170b971591d253 168 PANTHER PTHR34297:SF1 41 161 6.0E-39 T 16-09-2016 Spa2297_RS26225 e5b65a47b460b36675170b971591d253 168 PANTHER PTHR34297 41 161 6.0E-39 T 16-09-2016 Spa2297_RS01345 05ceaed5307ffbfaf2e67f00e23de485 310 Pfam PF01636 Phosphotransferase enzyme family 36 260 7.4E-35 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS01345 05ceaed5307ffbfaf2e67f00e23de485 310 PANTHER PTHR21310 5 302 1.0E-66 T 16-09-2016 Spa2297_RS01345 05ceaed5307ffbfaf2e67f00e23de485 310 SUPERFAMILY SSF56112 21 271 1.98E-48 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS01345 05ceaed5307ffbfaf2e67f00e23de485 310 Gene3D G3DSA:3.90.1200.10 107 271 3.1E-31 T 16-09-2016 Spa2297_RS01345 05ceaed5307ffbfaf2e67f00e23de485 310 PANTHER PTHR21310:SF14 5 302 1.0E-66 T 16-09-2016 Spa2297_RS02935 a2d4885e4b6f21439817c5be8423eb7d 318 SUPERFAMILY SSF51679 6 314 8.37E-78 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02935 a2d4885e4b6f21439817c5be8423eb7d 318 PANTHER PTHR30011 1 256 8.2E-58 T 16-09-2016 Spa2297_RS02935 a2d4885e4b6f21439817c5be8423eb7d 318 Pfam PF00296 Luciferase-like monooxygenase 10 256 3.3E-55 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS02935 a2d4885e4b6f21439817c5be8423eb7d 318 Gene3D G3DSA:3.20.20.30 6 314 2.3E-83 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS08050 b6ae6b505ea882ece7f6467f4b44fc72 137 Pfam PF01042 Endoribonuclease L-PSP 15 131 1.3E-16 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS08050 b6ae6b505ea882ece7f6467f4b44fc72 137 PANTHER PTHR11803 3 132 1.8E-49 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS08050 b6ae6b505ea882ece7f6467f4b44fc72 137 PANTHER PTHR11803:SF9 3 132 1.8E-49 T 16-09-2016 Spa2297_RS08050 b6ae6b505ea882ece7f6467f4b44fc72 137 SUPERFAMILY SSF55298 8 133 5.03E-23 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS08050 b6ae6b505ea882ece7f6467f4b44fc72 137 Gene3D G3DSA:3.30.1330.40 5 132 3.3E-24 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 PANTHER PTHR10489 47 272 6.3E-17 T 16-09-2016 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 SUPERFAMILY SSF49265 138 326 9.84E-16 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 SMART SM00060 233 319 43.0 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 SMART SM00060 46 119 2.7E-6 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 SMART SM00060 139 215 1.1E-8 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 SUPERFAMILY SSF49265 44 133 1.59E-13 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 Gene3D G3DSA:2.60.40.10 138 221 2.1E-17 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 Gene3D G3DSA:2.60.40.10 46 127 9.0E-13 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 Gene3D G3DSA:2.60.40.10 234 327 6.9E-7 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 Pfam PF00041 Fibronectin type III domain 142 211 6.7E-8 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS03030 014db0429224ada5cd18637b367445c7 333 Pfam PF00041 Fibronectin type III domain 49 122 9.6E-6 T 16-09-2016 IPR003961 Fibronectin type III GO:0005515 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 PANTHER PTHR30294 1 253 1.5E-32 T 16-09-2016 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 Pfam PF01061 ABC-2 type transporter 5 218 2.8E-32 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 103 128 4.9E-7 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 23 44 4.9E-7 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 4.9E-7 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS02635 ae51a8a091c277498b41fa5cecf0efbf 255 PIRSF PIRSF006648 1 255 9.9E-46 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 Gene3D G3DSA:1.10.3720.10 118 339 1.1E-29 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 PANTHER PTHR30465:SF69 29 343 1.6E-201 T 16-09-2016 Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 36 81 1.9E-9 T 16-09-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 SUPERFAMILY SSF161098 123 327 2.88E-28 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 146 342 7.1E-30 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS21560 3684edc43aa5af78a7c1cc3d6dfa5351 343 PANTHER PTHR30465 29 343 1.6E-201 T 16-09-2016 Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 SMART SM00387 294 384 2.4E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 Gene3D G3DSA:3.30.565.10 264 384 6.4E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 PANTHER PTHR24421 54 384 1.1E-69 T 16-09-2016 Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 PANTHER PTHR24421:SF26 54 384 1.1E-69 T 16-09-2016 Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 Pfam PF07730 Histidine kinase 194 260 8.0E-14 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS24680 4eabb61ad6c5dd997b79790e5e03a9ec 384 SUPERFAMILY SSF55874 262 383 1.02E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 Gene3D G3DSA:3.30.70.640 17 169 1.2E-64 T 16-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 SUPERFAMILY SSF55040 25 167 8.89E-57 T 16-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 16 170 36.339 T 16-09-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type UniPathway: UPA00344 Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 18 164 6.3E-63 T 16-09-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 UniPathway: UPA00344 Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 Pfam PF01967 MoaC family 29 162 3.3E-52 T 16-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 Spa2297_RS13845 04bf7649a1651dc8fd951ab2612bae6d 170 PANTHER PTHR22960 15 170 9.4E-95 T 16-09-2016 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 6.6E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.6E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.6E-8 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 SMART SM00422 1 69 2.3E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 SUPERFAMILY SSF46955 1 108 3.19E-25 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 Pfam PF13411 MerR HTH family regulatory protein 1 67 7.4E-15 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 Gene3D G3DSA:1.10.1660.10 1 110 4.2E-28 T 16-09-2016 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 PANTHER PTHR30204:SF4 1 108 5.0E-32 T 16-09-2016 Spa2297_RS31155 7368adb30effe727f1cb75b58d40f158 125 PANTHER PTHR30204 1 108 5.0E-32 T 16-09-2016 Spa2297_RS09980 65c4a751be9f07f5a401f63623a3fc72 102 PANTHER PTHR40040 1 102 4.5E-21 T 16-09-2016 Spa2297_RS22505 23e616bbd8631e427595c256ddc3f4b8 197 Pfam PF04978 Protein of unknown function (DUF664) 10 159 9.2E-43 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS22505 23e616bbd8631e427595c256ddc3f4b8 197 Gene3D G3DSA:1.20.120.450 9 162 1.9E-30 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS22505 23e616bbd8631e427595c256ddc3f4b8 197 SUPERFAMILY SSF109854 6 158 5.8E-35 T 16-09-2016 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 52 347 9.1E-62 T 16-09-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 Gene3D G3DSA:3.40.190.10 135 268 1.5E-18 T 16-09-2016 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 SUPERFAMILY SSF53850 51 282 6.04E-39 T 16-09-2016 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 PANTHER PTHR30024:SF1 50 343 1.7E-52 T 16-09-2016 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 Pfam PF13379 NMT1-like family 50 285 1.1E-29 T 16-09-2016 Spa2297_RS25755 a8695f794c3b9f6219ba41c4a4e9c0b8 367 PANTHER PTHR30024 50 343 1.7E-52 T 16-09-2016 Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 PANTHER PTHR24421:SF26 71 420 1.5E-93 T 16-09-2016 Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 SMART SM00387 322 418 8.7E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 Pfam PF07730 Histidine kinase 211 276 5.9E-19 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 PANTHER PTHR24421 71 420 1.5E-93 T 16-09-2016 Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 SUPERFAMILY SSF55874 303 415 1.39E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15555 cfc5710e846c7a5567de6078b4f40f70 420 Gene3D G3DSA:3.30.565.10 307 415 8.1E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14890 b35ab853f8aa36abc8de722fae17cf61 191 Pfam PF02342 TerD domain 1 187 6.8E-84 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS14890 b35ab853f8aa36abc8de722fae17cf61 191 PANTHER PTHR32097 1 191 3.3E-93 T 16-09-2016 Spa2297_RS14890 b35ab853f8aa36abc8de722fae17cf61 191 Gene3D G3DSA:2.60.60.30 18 185 2.6E-73 T 16-09-2016 Spa2297_RS00185 644e1931285bb1fb3393476f12c5ab6b 194 Gene3D G3DSA:1.25.40.10 17 172 3.8E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00185 644e1931285bb1fb3393476f12c5ab6b 194 Pfam PF13374 Tetratricopeptide repeat 95 134 2.0E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS00185 644e1931285bb1fb3393476f12c5ab6b 194 Pfam PF13424 Tetratricopeptide repeat 18 84 3.2E-7 T 16-09-2016 Spa2297_RS00185 644e1931285bb1fb3393476f12c5ab6b 194 SUPERFAMILY SSF48452 48 171 8.63E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 16-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 Pfam PF01227 GTP cyclohydrolase I 22 198 3.5E-76 T 16-09-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 SUPERFAMILY SSF55620 14 198 2.22E-76 T 16-09-2016 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 198 2.5E-72 T 16-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 199 41.953 T 16-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 16-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 Gene3D G3DSA:1.10.286.10 16 67 2.9E-24 T 16-09-2016 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 PANTHER PTHR11109 15 201 1.5E-110 T 16-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 Spa2297_RS18185 929a9037ebe1a0219661b57a84a69dfe 201 Gene3D G3DSA:3.30.1130.10 70 199 2.1E-59 T 16-09-2016 Spa2297_RS26320 88c597c987e693bb37638d56f904b592 169 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 12 165 8.1E-60 T 16-09-2016 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 Spa2297_RS26320 88c597c987e693bb37638d56f904b592 169 Pfam PF09349 OHCU decarboxylase 13 161 9.9E-35 T 16-09-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 Spa2297_RS26320 88c597c987e693bb37638d56f904b592 169 Gene3D G3DSA:1.10.3330.10 15 166 1.9E-43 T 16-09-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 Spa2297_RS26320 88c597c987e693bb37638d56f904b592 169 SUPERFAMILY SSF158694 8 165 1.31E-40 T 16-09-2016 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PANTHER PTHR10992 3 257 2.6E-73 T 16-09-2016 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 Gene3D G3DSA:3.40.50.1820 5 256 7.6E-57 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 Pfam PF02627 Carboxymuconolactone decarboxylase family 347 429 3.4E-23 T 16-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PANTHER PTHR10992:SF818 3 257 2.6E-73 T 16-09-2016 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 SUPERFAMILY SSF53474 5 255 2.01E-58 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 Gene3D G3DSA:1.20.1290.10 333 437 8.2E-26 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 SUPERFAMILY SSF69118 316 435 1.18E-34 T 16-09-2016 IPR029032 AhpD-like Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 7.2E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.2E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 7.2E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 7.2E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS26700 c522b88ca734f27a35e3500e5ff68e9d 440 Pfam PF12697 Alpha/beta hydrolase family 28 249 1.6E-13 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS31665 533d665524198129a87b1530cd55a01e 340 Gene3D G3DSA:1.10.3470.10 3 334 1.2E-96 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS31665 533d665524198129a87b1530cd55a01e 340 Pfam PF01032 FecCD transport family 12 332 1.1E-86 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31665 533d665524198129a87b1530cd55a01e 340 PANTHER PTHR30472 1 338 2.4E-121 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS31665 533d665524198129a87b1530cd55a01e 340 SUPERFAMILY SSF81345 3 332 1.57E-72 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS31665 533d665524198129a87b1530cd55a01e 340 PANTHER PTHR30472:SF32 1 338 2.4E-121 T 16-09-2016 Spa2297_RS29315 b908b6060ea8cd58821b5440ea761d26 251 Pfam PF02585 GlcNAc-PI de-N-acetylase 42 166 1.3E-22 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS29315 b908b6060ea8cd58821b5440ea761d26 251 Gene3D G3DSA:3.40.50.10320 39 235 6.8E-44 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS29315 b908b6060ea8cd58821b5440ea761d26 251 PANTHER PTHR12993 20 197 1.4E-22 T 16-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Spa2297_RS29315 b908b6060ea8cd58821b5440ea761d26 251 SUPERFAMILY SSF102588 38 248 1.83E-41 T 16-09-2016 IPR024078 Putative deacetylase LmbE-like domain Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 29 198 5.2E-35 T 16-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 SUPERFAMILY SSF52540 21 223 1.04E-35 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 Gene3D G3DSA:3.40.50.300 25 214 6.1E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 PANTHER PTHR31715 15 225 4.6E-112 T 16-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 PIRSF PIRSF005624 7 225 2.6E-46 T 16-09-2016 Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 27 217 1.5E-80 T 16-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 Spa2297_RS04465 34febef60fa10b2ae9fbe48e631e03e7 225 Hamap MF_01389 Urease accessory protein UreG [ureG]. 25 223 43.046 T 16-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 Spa2297_RS14925 dadf15c9a0c2e336997da662c5a7c749 230 SUPERFAMILY SSF141571 45 218 3.04E-37 T 16-09-2016 Spa2297_RS14925 dadf15c9a0c2e336997da662c5a7c749 230 PANTHER PTHR14136 40 189 7.1E-21 T 16-09-2016 Spa2297_RS14925 dadf15c9a0c2e336997da662c5a7c749 230 Pfam PF00805 Pentapeptide repeats (8 copies) 155 188 4.1E-4 T 16-09-2016 IPR001646 Pentapeptide repeat Spa2297_RS14925 dadf15c9a0c2e336997da662c5a7c749 230 Pfam PF13599 Pentapeptide repeats (9 copies) 59 134 9.3E-10 T 16-09-2016 IPR001646 Pentapeptide repeat Spa2297_RS00715 89c152a5881403b260b6b66fee8443a8 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 273 2.8E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00715 89c152a5881403b260b6b66fee8443a8 284 SUPERFAMILY SSF161098 19 284 2.62E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS00715 89c152a5881403b260b6b66fee8443a8 284 PANTHER PTHR32243 7 284 1.3E-95 T 16-09-2016 Spa2297_RS00715 89c152a5881403b260b6b66fee8443a8 284 PANTHER PTHR32243:SF31 7 284 1.3E-95 T 16-09-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 Spa2297_RS00715 89c152a5881403b260b6b66fee8443a8 284 Gene3D G3DSA:1.10.3720.10 19 270 4.0E-53 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS16785 a30925377c6ac8aaffe109e62d131244 253 SUPERFAMILY SSF75217 100 244 1.1E-29 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS16785 a30925377c6ac8aaffe109e62d131244 253 PANTHER PTHR12029 18 243 2.7E-31 T 16-09-2016 Spa2297_RS16785 a30925377c6ac8aaffe109e62d131244 253 Pfam PF00588 SpoU rRNA Methylase family 111 241 1.2E-24 T 16-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spa2297_RS16785 a30925377c6ac8aaffe109e62d131244 253 Gene3D G3DSA:3.40.1280.10 109 244 4.2E-28 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 345 365 - T 16-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 Pfam PF00860 Permease family 15 398 3.2E-92 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 428 3.7E-107 T 16-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 TIGRFAM TIGR03173 pbuX: xanthine permease 19 430 1.7E-157 T 16-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 PANTHER PTHR11119:SF3 4 431 1.4E-109 T 16-09-2016 Spa2297_RS26345 43b0f1f83639b2242486677bbda126c8 468 PANTHER PTHR11119 4 431 1.4E-109 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS25330 e6ee4127f59e339512021981bc4915a0 464 SUPERFAMILY SSF52266 4 213 5.72E-37 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS25330 e6ee4127f59e339512021981bc4915a0 464 PANTHER PTHR31321:SF29 117 208 2.6E-18 T 16-09-2016 Spa2297_RS25330 e6ee4127f59e339512021981bc4915a0 464 Gene3D G3DSA:3.40.50.1110 4 212 2.6E-49 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS25330 e6ee4127f59e339512021981bc4915a0 464 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 186 1.9E-9 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS25330 e6ee4127f59e339512021981bc4915a0 464 PANTHER PTHR31321 117 208 2.6E-18 T 16-09-2016 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 326 3.2E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 SUPERFAMILY SSF161098 197 335 2.35E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 SUPERFAMILY SSF161098 36 168 2.35E-60 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 Gene3D G3DSA:1.10.3720.10 92 334 7.6E-64 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 PANTHER PTHR32243:SF40 203 339 1.1E-94 T 16-09-2016 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 PANTHER PTHR32243:SF40 31 172 1.1E-94 T 16-09-2016 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 PANTHER PTHR32243 203 339 1.1E-94 T 16-09-2016 Spa2297_RS01310 748e1a4279138b8ebd4463f6606095af 339 PANTHER PTHR32243 31 172 1.1E-94 T 16-09-2016 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 Pfam PF00072 Response regulator receiver domain 7 118 3.8E-27 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 PANTHER PTHR26402:SF570 4 224 2.0E-85 T 16-09-2016 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 PANTHER PTHR26402 4 224 2.0E-85 T 16-09-2016 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 SMART SM00448 4 117 5.4E-28 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 SMART SM00421 155 212 4.6E-18 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 Gene3D G3DSA:1.10.10.10 125 219 1.6E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 SUPERFAMILY SSF46894 148 218 1.73E-18 T 16-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 9.7E-13 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 SUPERFAMILY SSF52172 4 136 6.26E-32 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.1E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.1E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.1E-10 T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 16-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spa2297_RS26475 6ad821855ac2e634320217afc7c27767 233 Gene3D G3DSA:3.40.50.2300 2 124 8.8E-35 T 16-09-2016 Spa2297_RS20070 d5801c8c8096ed13971c131d8867503f 303 PANTHER PTHR10587 116 303 2.7E-32 T 16-09-2016 Spa2297_RS20070 d5801c8c8096ed13971c131d8867503f 303 Gene3D G3DSA:3.20.20.370 107 303 3.2E-41 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS20070 d5801c8c8096ed13971c131d8867503f 303 SUPERFAMILY SSF88713 109 302 1.2E-40 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS20070 d5801c8c8096ed13971c131d8867503f 303 PANTHER PTHR10587:SF71 116 303 2.7E-32 T 16-09-2016 Spa2297_RS20070 d5801c8c8096ed13971c131d8867503f 303 Pfam PF01522 Polysaccharide deacetylase 117 236 3.2E-27 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS26155 11ec37f97f75445a21cea27f32b86d8a 262 Gene3D G3DSA:1.25.40.10 59 238 5.5E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 Gene3D G3DSA:2.60.120.10 85 187 5.6E-12 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 SUPERFAMILY SSF47413 11 78 9.85E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 SMART SM00530 18 73 3.2E-15 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 SUPERFAMILY SSF51182 69 189 1.62E-18 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 PANTHER PTHR10245 4 192 9.1E-76 T 16-09-2016 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 Pfam PF01381 Helix-turn-helix 19 71 2.0E-13 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 Gene3D G3DSA:1.10.260.40 12 81 2.4E-19 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS28335 b57921bd07dc017f49043118ede1ceb5 192 PANTHER PTHR10245:SF21 4 192 9.1E-76 T 16-09-2016 Spa2297_RS14000 ab7fef8774b2a2b4af0e4848d572c9a4 149 Gene3D G3DSA:1.10.20.10 1 149 2.2E-70 T 16-09-2016 IPR009072 Histone-fold GO:0046982 Spa2297_RS14000 ab7fef8774b2a2b4af0e4848d572c9a4 149 SUPERFAMILY SSF47113 2 149 1.34E-56 T 16-09-2016 IPR009072 Histone-fold GO:0046982 Spa2297_RS14000 ab7fef8774b2a2b4af0e4848d572c9a4 149 Pfam PF09123 Domain of unknown function (DUF1931) 9 146 7.4E-60 T 16-09-2016 IPR015207 Protein of unknown function DUF1931 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 SUPERFAMILY SSF51726 15 351 3.31E-108 T 16-09-2016 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 Gene3D G3DSA:3.20.20.210 15 351 1.9E-145 T 16-09-2016 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 PANTHER PTHR21091 17 350 4.7E-128 T 16-09-2016 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 17 351 9.5E-131 T 16-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 PANTHER PTHR21091:SF2 17 350 4.7E-128 T 16-09-2016 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 33 42 - T 16-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 17 353 47.673 T 16-09-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 150 166 - T 16-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS25360 607122b5f9d9cdbee1134b329a3a20f5 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 20 350 1.1E-122 T 16-09-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 Pfam PF07398 MDMPI C-terminal domain 148 225 3.2E-7 T 16-09-2016 IPR010872 MDMPI C-terminal Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 Gene3D G3DSA:1.20.120.450 10 136 5.2E-5 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 SUPERFAMILY SSF55718 148 227 2.71E-17 T 16-09-2016 IPR003033 SCP2 sterol-binding domain Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 140 2.4E-22 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 SUPERFAMILY SSF109854 1 146 4.81E-40 T 16-09-2016 Spa2297_RS07905 32129c578a0135b0bf8afe3592b4baee 228 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 209 3.1E-37 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 SMART SM00642 211 622 3.3E-8 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 SUPERFAMILY SSF81296 41 187 8.0E-39 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 Pfam PF00128 Alpha amylase, catalytic domain 243 347 9.1E-7 T 16-09-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 Gene3D G3DSA:2.60.40.1180 642 754 3.2E-23 T 16-09-2016 IPR013780 Glycosyl hydrolase, all-beta Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 SUPERFAMILY SSF51445 190 523 3.73E-131 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 SUPERFAMILY SSF51445 552 630 3.73E-131 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 PANTHER PTHR10357:SF74 652 754 0.0 T 16-09-2016 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 42 753 0.0 T 16-09-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 SUPERFAMILY SSF51011 643 754 3.52E-18 T 16-09-2016 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 PANTHER PTHR10357 652 754 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 PANTHER PTHR10357:SF74 26 633 0.0 T 16-09-2016 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 46 140 4.1E-18 T 16-09-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 Gene3D G3DSA:3.20.20.80 206 631 4.5E-122 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 PANTHER PTHR10357 26 633 0.0 T 16-09-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 Spa2297_RS23060 4badc3e203b2bf17bd675906397d6f52 755 Gene3D G3DSA:2.60.40.10 41 205 1.5E-49 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS21200 1e892bacd4671bc60f57ef2646014128 198 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 19 57 4.2E-8 T 16-09-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Spa2297_RS25700 749f8b62398bfe0ac7dc79370a34f3f3 287 Pfam PF01636 Phosphotransferase enzyme family 35 235 1.2E-13 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS25700 749f8b62398bfe0ac7dc79370a34f3f3 287 SUPERFAMILY SSF56112 3 258 1.2E-31 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS25700 749f8b62398bfe0ac7dc79370a34f3f3 287 Gene3D G3DSA:3.90.1200.10 93 271 1.8E-12 T 16-09-2016 Spa2297_RS06575 c315796bb7aaa8a9cab9c4465deacfa9 314 Gene3D G3DSA:1.25.40.10 81 170 1.9E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS06575 c315796bb7aaa8a9cab9c4465deacfa9 314 Gene3D G3DSA:1.25.40.10 15 25 1.9E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS24635 7f341ab7460fdca839c2572d7758d91c 544 Pfam PF13830 Domain of unknown function (DUF4192) 44 388 1.3E-91 T 16-09-2016 IPR025447 Protein of unknown function DUF4192 Spa2297_RS27030 f89f412307048e339f9baea9dc0b5388 653 Pfam PF17128 Domain of unknown function (DUF5107) 58 347 3.6E-36 T 16-09-2016 IPR033396 Domain of unknown function DUF5107 Spa2297_RS27030 f89f412307048e339f9baea9dc0b5388 653 SUPERFAMILY SSF74650 71 196 1.63E-5 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS27030 f89f412307048e339f9baea9dc0b5388 653 Gene3D G3DSA:1.25.40.10 471 616 4.8E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 Gene3D G3DSA:1.10.8.60 123 199 7.6E-8 T 16-09-2016 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 Pfam PF06144 DNA polymerase III, delta subunit 3 166 1.7E-10 T 16-09-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 Gene3D G3DSA:3.40.50.300 3 92 7.6E-9 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 Gene3D G3DSA:1.20.272.20 200 309 3.5E-4 T 16-09-2016 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 SUPERFAMILY SSF48019 190 308 2.04E-14 T 16-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 1 306 4.7E-33 T 16-09-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 Spa2297_RS10805 b33cbad960026cfaa1efb092a8d4b8ca 316 PANTHER PTHR34388 1 316 1.5E-68 T 16-09-2016 Spa2297_RS16070 002eae8be7e290eb885e28fafb04e998 134 PANTHER PTHR33204:SF7 10 120 1.8E-59 T 16-09-2016 Spa2297_RS16070 002eae8be7e290eb885e28fafb04e998 134 SUPERFAMILY SSF46785 7 117 4.09E-29 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16070 002eae8be7e290eb885e28fafb04e998 134 Pfam PF01638 HxlR-like helix-turn-helix 19 104 2.0E-25 T 16-09-2016 IPR002577 Helix-turn-helix, HxlR type Spa2297_RS16070 002eae8be7e290eb885e28fafb04e998 134 PANTHER PTHR33204 10 120 1.8E-59 T 16-09-2016 Spa2297_RS16070 002eae8be7e290eb885e28fafb04e998 134 Gene3D G3DSA:1.10.10.10 7 116 1.2E-39 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS16650 38730846a9d123c1decf03f547e178f5 182 Gene3D G3DSA:1.10.260.40 25 62 4.5E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS16650 38730846a9d123c1decf03f547e178f5 182 SUPERFAMILY SSF47413 22 65 2.84E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 PANTHER PTHR37418:SF2 4 90 1.5E-159 T 16-09-2016 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 PANTHER PTHR37418 4 90 1.5E-159 T 16-09-2016 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 Gene3D G3DSA:3.20.20.70 5 295 1.1E-116 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 Pfam PF05853 beta-keto acid cleavage enzyme 7 293 1.1E-102 T 16-09-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 PANTHER PTHR37418 108 296 1.5E-159 T 16-09-2016 Spa2297_RS03250 73e6a3a1de02bc74fe9d610217080ae7 297 PANTHER PTHR37418:SF2 108 296 1.5E-159 T 16-09-2016 Spa2297_RS17405 c3b1afb05365749ecd3bf522ab80f0d7 451 SUPERFAMILY SSF52540 153 368 7.17E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17405 c3b1afb05365749ecd3bf522ab80f0d7 451 PANTHER PTHR22683:SF41 7 405 2.7E-146 T 16-09-2016 Spa2297_RS17405 c3b1afb05365749ecd3bf522ab80f0d7 451 Gene3D G3DSA:3.40.50.300 157 362 2.0E-14 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS17405 c3b1afb05365749ecd3bf522ab80f0d7 451 PANTHER PTHR22683 7 405 2.7E-146 T 16-09-2016 Spa2297_RS17405 c3b1afb05365749ecd3bf522ab80f0d7 451 Pfam PF01580 FtsK/SpoIIIE family 140 278 5.8E-30 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS28060 e4b9cd52d86e78b47f042cfd6f8bf292 427 SMART SM00631 45 263 1.9E-4 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS28060 e4b9cd52d86e78b47f042cfd6f8bf292 427 SUPERFAMILY SSF53187 51 246 3.11E-39 T 16-09-2016 Spa2297_RS28060 e4b9cd52d86e78b47f042cfd6f8bf292 427 Pfam PF00246 Zinc carboxypeptidase 53 229 7.1E-20 T 16-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Spa2297_RS28060 e4b9cd52d86e78b47f042cfd6f8bf292 427 Gene3D G3DSA:3.40.630.10 42 317 2.0E-35 T 16-09-2016 Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 PANTHER PTHR30595:SF4 1 344 1.8E-113 T 16-09-2016 Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 Gene3D G3DSA:1.10.10.10 6 66 1.9E-13 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 Pfam PF13280 WYL domain 145 337 9.5E-32 T 16-09-2016 IPR026881 WYL domain Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 Pfam PF08279 HTH domain 7 62 5.3E-9 T 16-09-2016 IPR013196 Helix-turn-helix, type 11 Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 SUPERFAMILY SSF46785 7 62 2.9E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18825 31150d7fffd30d971db316dfb9e3ead9 348 PANTHER PTHR30595 1 344 1.8E-113 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 PANTHER PTHR30061:SF14 7 436 9.2E-124 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 PANTHER PTHR30061 7 436 9.2E-124 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 Gene3D G3DSA:3.40.190.10 43 151 3.7E-32 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 Gene3D G3DSA:3.40.190.10 320 352 3.7E-32 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 Pfam PF01547 Bacterial extracellular solute-binding protein 52 333 1.2E-32 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 SUPERFAMILY SSF53850 42 425 5.98E-61 T 16-09-2016 Spa2297_RS30375 45118c8e2718a8fa55493866b638d71a 443 Gene3D G3DSA:3.40.190.10 152 319 5.4E-32 T 16-09-2016 Spa2297_RS05415 2761fd376a93e5807ae30980e673c211 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 12 89 1.0E-10 T 16-09-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 Spa2297_RS05415 2761fd376a93e5807ae30980e673c211 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.678 T 16-09-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 Spa2297_RS05415 2761fd376a93e5807ae30980e673c211 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 1.3E-24 T 16-09-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 Spa2297_RS05415 2761fd376a93e5807ae30980e673c211 90 PANTHER PTHR21256 5 90 1.2E-28 T 16-09-2016 Spa2297_RS05415 2761fd376a93e5807ae30980e673c211 90 SUPERFAMILY SSF101386 5 90 5.23E-21 T 16-09-2016 Spa2297_RS19305 e934dc45704f738f82e629956dd975c4 312 PANTHER PTHR22726:SF7 24 258 3.9E-57 T 16-09-2016 Spa2297_RS19305 e934dc45704f738f82e629956dd975c4 312 PANTHER PTHR22726 24 258 3.9E-57 T 16-09-2016 Spa2297_RS19305 e934dc45704f738f82e629956dd975c4 312 Gene3D G3DSA:3.30.2010.10 120 198 8.6E-11 T 16-09-2016 Spa2297_RS19305 e934dc45704f738f82e629956dd975c4 312 Pfam PF01435 Peptidase family M48 139 199 1.2E-7 T 16-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PANTHER PTHR13789 2 402 2.8E-69 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 1.0E-17 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.0E-17 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 1.0E-17 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.0E-17 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 Gene3D G3DSA:3.50.50.60 1 182 1.3E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 Gene3D G3DSA:3.50.50.60 280 353 1.3E-33 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 Pfam PF01494 FAD binding domain 2 348 1.7E-17 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 PANTHER PTHR13789:SF241 2 402 2.8E-69 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 SUPERFAMILY SSF54373 183 284 6.28E-12 T 16-09-2016 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 SUPERFAMILY SSF51905 280 364 1.2E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS23925 95696ad71e40a3cc706d4138d469d568 429 SUPERFAMILY SSF51905 1 177 1.2E-51 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 Pfam PF02608 Basic membrane protein 47 316 4.1E-57 T 16-09-2016 IPR003760 Basic membrane lipoprotein GO:0005886 Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 SUPERFAMILY SSF53822 51 296 5.18E-15 T 16-09-2016 IPR028082 Periplasmic binding protein-like I Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 Gene3D G3DSA:3.40.50.2300 168 253 3.9E-5 T 16-09-2016 Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 PANTHER PTHR34296:SF2 14 346 7.5E-126 T 16-09-2016 Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 PANTHER PTHR34296 14 346 7.5E-126 T 16-09-2016 Spa2297_RS20670 5f5ce40d23f723662f910bc50bcaa4d0 346 Gene3D G3DSA:3.40.50.2300 36 167 1.1E-48 T 16-09-2016 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 Pfam PF01374 Glycosyl hydrolase family 46 82 291 3.9E-94 T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 Gene3D G3DSA:1.20.141.10 177 301 1.5E-59 T 16-09-2016 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 PIRSF PIRSF036551 11 303 1.2E-104 T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 88 123 - T 16-09-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 Gene3D G3DSA:3.30.386.10 68 176 4.3E-50 T 16-09-2016 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 Spa2297_RS08235 7ca1005ad33f598c0de28c2f5378ac35 303 SUPERFAMILY SSF53955 68 301 2.36E-89 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 Gene3D G3DSA:3.40.190.10 206 323 4.8E-27 T 16-09-2016 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 PIRSF PIRSF002741 7 543 8.0E-62 T 16-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 464 2.2E-45 T 16-09-2016 IPR000914 Solute-binding protein family 5 domain Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 PANTHER PTHR30290 10 541 1.4E-120 T 16-09-2016 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 Gene3D G3DSA:3.90.76.10 50 205 5.1E-32 T 16-09-2016 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 Gene3D G3DSA:3.10.105.10 324 515 7.3E-38 T 16-09-2016 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 PANTHER PTHR30290:SF10 10 541 1.4E-120 T 16-09-2016 Spa2297_RS21585 57ee74ba243512a4cb9966a6aef5d750 544 SUPERFAMILY SSF53850 37 542 4.81E-90 T 16-09-2016 Spa2297_RS27100 8f72ed3103f1cf821e048acd1bad6c3c 60 PANTHER PTHR35344 1 58 2.4E-31 T 16-09-2016 Spa2297_RS27100 8f72ed3103f1cf821e048acd1bad6c3c 60 Pfam PF00741 Gas vesicle protein 10 48 4.0E-14 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS27100 8f72ed3103f1cf821e048acd1bad6c3c 60 PANTHER PTHR35344:SF2 1 58 2.4E-31 T 16-09-2016 Spa2297_RS23205 94761412a57bf4852236d1f0c0d8a76d 91 PANTHER PTHR40040 1 91 1.1E-18 T 16-09-2016 Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 SUPERFAMILY SSF53686 5 304 2.49E-75 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 Gene3D G3DSA:3.40.50.1100 70 312 2.3E-60 T 16-09-2016 Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 301 6.1E-69 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 PANTHER PTHR10314:SF17 2 316 2.2E-93 T 16-09-2016 Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 16-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Spa2297_RS02225 b0c3844bffe00988437f8bee86868f22 319 PANTHER PTHR10314 2 316 2.2E-93 T 16-09-2016 Spa2297_RS22120 d57e549036f26f0d8be342a572c8a527 168 PANTHER PTHR23091 1 168 1.2E-32 T 16-09-2016 Spa2297_RS22120 d57e549036f26f0d8be342a572c8a527 168 PANTHER PTHR23091:SF276 1 168 1.2E-32 T 16-09-2016 Spa2297_RS22120 d57e549036f26f0d8be342a572c8a527 168 SUPERFAMILY SSF55729 1 148 2.57E-28 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22120 d57e549036f26f0d8be342a572c8a527 168 Gene3D G3DSA:3.40.630.30 1 151 3.4E-27 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22120 d57e549036f26f0d8be342a572c8a527 168 Pfam PF00583 Acetyltransferase (GNAT) family 60 143 1.9E-14 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 PANTHER PTHR11922:SF5 10 353 2.4E-101 T 16-09-2016 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 36.036 T 16-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 Gene3D G3DSA:3.40.1030.10 86 353 2.5E-106 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 SUPERFAMILY SSF47648 17 83 4.06E-20 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 80 1.1E-18 T 16-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 Gene3D G3DSA:1.20.970.10 16 80 2.4E-24 T 16-09-2016 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 SUPERFAMILY SSF52418 87 353 4.71E-86 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 Pfam PF00591 Glycosyl transferase family, a/b domain 88 341 5.1E-84 T 16-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 21 350 4.1E-111 T 16-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 Spa2297_RS08845 9d5cee62365017e411c05ce48b568300 354 PANTHER PTHR11922 10 353 2.4E-101 T 16-09-2016 Spa2297_RS16390 7fc509f1a4f964ef15b15ce158cb1db1 139 Pfam PF03928 Haem-degrading 9 135 6.8E-30 T 16-09-2016 IPR005624 Haem-degrading Spa2297_RS16390 7fc509f1a4f964ef15b15ce158cb1db1 139 PANTHER PTHR34309 1 138 5.4E-38 T 16-09-2016 Spa2297_RS16390 7fc509f1a4f964ef15b15ce158cb1db1 139 PANTHER PTHR34309:SF1 1 138 5.4E-38 T 16-09-2016 Spa2297_RS16390 7fc509f1a4f964ef15b15ce158cb1db1 139 SUPERFAMILY SSF143744 6 138 9.81E-36 T 16-09-2016 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 Pfam PF13411 MerR HTH family regulatory protein 7 73 1.8E-20 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 PANTHER PTHR30204 1 85 4.1E-45 T 16-09-2016 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 SMART SM00422 7 75 1.6E-16 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 SUPERFAMILY SSF46955 7 78 1.19E-18 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 Gene3D G3DSA:1.10.1660.10 7 79 2.1E-20 T 16-09-2016 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 2.1E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 2.1E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 2.1E-5 T 16-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spa2297_RS13810 c80cfdfbd4e637a26469bb1dd3eacf93 215 PANTHER PTHR30204:SF13 1 85 4.1E-45 T 16-09-2016 Spa2297_RS09740 ca1cc11a863e02eb67fba06bc73526ac 188 PANTHER PTHR11080 7 184 9.9E-50 T 16-09-2016 Spa2297_RS09740 ca1cc11a863e02eb67fba06bc73526ac 188 PANTHER PTHR11080:SF17 7 184 9.9E-50 T 16-09-2016 Spa2297_RS09740 ca1cc11a863e02eb67fba06bc73526ac 188 Gene3D G3DSA:3.40.50.850 10 185 4.1E-42 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS09740 ca1cc11a863e02eb67fba06bc73526ac 188 SUPERFAMILY SSF52499 13 185 1.05E-42 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS09740 ca1cc11a863e02eb67fba06bc73526ac 188 Pfam PF00857 Isochorismatase family 18 182 7.8E-31 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS20430 cbcf9efa6c4d7bf2495e953672297b08 192 Gene3D G3DSA:3.90.1140.10 8 175 2.9E-26 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS20430 cbcf9efa6c4d7bf2495e953672297b08 192 Pfam PF13563 2'-5' RNA ligase superfamily 13 157 3.2E-22 T 16-09-2016 Spa2297_RS20430 cbcf9efa6c4d7bf2495e953672297b08 192 SUPERFAMILY SSF55144 6 173 6.02E-32 T 16-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase Spa2297_RS20430 cbcf9efa6c4d7bf2495e953672297b08 192 PANTHER PTHR40037 2 178 5.6E-54 T 16-09-2016 Spa2297_RS20430 cbcf9efa6c4d7bf2495e953672297b08 192 PANTHER PTHR40037:SF1 2 178 5.6E-54 T 16-09-2016 Spa2297_RS13945 2e1564edd5b6657de8327ca4f34870e1 172 Pfam PF13420 Acetyltransferase (GNAT) domain 15 167 2.9E-20 T 16-09-2016 Spa2297_RS13945 2e1564edd5b6657de8327ca4f34870e1 172 PANTHER PTHR23091:SF187 10 172 6.2E-26 T 16-09-2016 Spa2297_RS13945 2e1564edd5b6657de8327ca4f34870e1 172 PANTHER PTHR23091 10 172 6.2E-26 T 16-09-2016 Spa2297_RS13945 2e1564edd5b6657de8327ca4f34870e1 172 Gene3D G3DSA:3.40.630.30 7 172 5.4E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS13945 2e1564edd5b6657de8327ca4f34870e1 172 SUPERFAMILY SSF55729 10 172 8.41E-30 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS29880 410f67e8e9f281510c7104f15d7db942 222 Pfam PF14016 Protein of unknown function (DUF4232) 87 214 2.5E-33 T 16-09-2016 IPR025326 Protein of unknown function DUF4232 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 Pfam PF01547 Bacterial extracellular solute-binding protein 45 334 3.9E-41 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 Gene3D G3DSA:3.40.190.10 163 352 6.4E-38 T 16-09-2016 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 Gene3D G3DSA:3.40.190.10 31 162 9.6E-16 T 16-09-2016 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 SUPERFAMILY SSF53850 28 406 1.6E-63 T 16-09-2016 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 PANTHER PTHR30061:SF24 2 418 3.9E-109 T 16-09-2016 Spa2297_RS29065 3b666e3bfb7fc0776808548196c5cd59 422 PANTHER PTHR30061 2 418 3.9E-109 T 16-09-2016 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 76 4.3E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 SUPERFAMILY SSF46689 20 104 1.55E-17 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 1.3E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.3E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 Gene3D G3DSA:1.10.357.10 21 202 5.0E-38 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 SUPERFAMILY SSF48498 99 201 4.08E-9 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 PANTHER PTHR30055:SF19 17 180 2.1E-53 T 16-09-2016 Spa2297_RS20930 708fd82b573dcdcd11347d7978424c3a 203 PANTHER PTHR30055 17 180 2.1E-53 T 16-09-2016 Spa2297_RS09940 89c49c48c9e24366a77299a7265b6739 271 PANTHER PTHR32097 1 231 3.9E-76 T 16-09-2016 Spa2297_RS09940 89c49c48c9e24366a77299a7265b6739 271 PANTHER PTHR32097:SF4 1 231 3.9E-76 T 16-09-2016 Spa2297_RS09940 89c49c48c9e24366a77299a7265b6739 271 Pfam PF02342 TerD domain 1 174 3.6E-46 T 16-09-2016 IPR003325 TerD domain GO:0006950 Spa2297_RS09940 89c49c48c9e24366a77299a7265b6739 271 Gene3D G3DSA:2.60.60.30 16 172 1.6E-31 T 16-09-2016 Spa2297_RS29660 bbe80e721e1970b63924172e245accea 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 323 4.2E-41 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS29660 bbe80e721e1970b63924172e245accea 346 PANTHER PTHR32196:SF29 1 345 1.2E-170 T 16-09-2016 Spa2297_RS29660 bbe80e721e1970b63924172e245accea 346 PANTHER PTHR32196 1 345 1.2E-170 T 16-09-2016 Spa2297_RS19320 beaf82a48d0aa8af852cb2bddf4f554a 539 Pfam PF01943 Polysaccharide biosynthesis protein 31 230 2.4E-5 T 16-09-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 SUPERFAMILY SSF52833 41 146 9.77E-34 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 Gene3D G3DSA:3.40.30.10 45 142 1.7E-29 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 PANTHER PTHR10438 29 143 7.0E-34 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 PANTHER PTHR10438:SF281 29 143 7.0E-34 T 16-09-2016 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 PRINTS PR00421 Thioredoxin family signature 59 67 6.7E-6 T 16-09-2016 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 PRINTS PR00421 Thioredoxin family signature 67 76 6.7E-6 T 16-09-2016 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 PRINTS PR00421 Thioredoxin family signature 107 118 6.7E-6 T 16-09-2016 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 Pfam PF00085 Thioredoxin 45 141 6.1E-26 T 16-09-2016 IPR013766 Thioredoxin domain GO:0045454 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 ProSitePatterns PS00194 Thioredoxin family active site. 60 78 - T 16-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 Spa2297_RS14045 2966179529f46013117d9046acdf854b 156 TIGRFAM TIGR01068 thioredoxin: thioredoxin 46 142 1.2E-31 T 16-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 PANTHER PTHR32282:SF10 1 748 0.0 T 16-09-2016 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:3.40.50.300 5 52 1.2E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:3.40.50.300 458 512 1.9E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:3.40.50.300 634 749 1.9E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:3.40.50.300 328 444 1.2E-50 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:1.10.8.280 148 261 2.8E-7 T 16-09-2016 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 PANTHER PTHR32282 1 748 0.0 T 16-09-2016 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:1.20.1580.10 516 633 3.2E-36 T 16-09-2016 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 SUPERFAMILY SSF52540 260 432 4.27E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 SUPERFAMILY SSF52540 5 113 4.27E-31 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Pfam PF00005 ABC transporter 468 670 7.7E-11 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 SUPERFAMILY SSF52540 461 722 2.11E-37 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 SMART SM00382 477 750 0.0014 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 SMART SM00382 24 415 5.7 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:1.20.1580.10 262 327 4.5E-28 T 16-09-2016 Spa2297_RS27970 d61cdbe8d0691fc6ff78b95d19386de4 752 Gene3D G3DSA:1.20.1580.10 94 143 4.5E-28 T 16-09-2016 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 PANTHER PTHR10192 19 448 5.7E-174 T 16-09-2016 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Gene3D G3DSA:3.40.980.10 201 378 1.8E-60 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 SMART SM00852 219 365 1.5E-43 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 SUPERFAMILY SSF63882 22 215 3.14E-50 T 16-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 216 361 1.8E-33 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Gene3D G3DSA:2.170.190.11 65 169 4.5E-33 T 16-09-2016 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Pfam PF03453 MoeA N-terminal region (domain I and II) 24 206 2.4E-34 T 16-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Gene3D G3DSA:2.40.340.10 379 447 1.5E-21 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Pfam PF00994 Probable molybdopterin binding domain 220 364 1.0E-30 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Pfam PF03454 MoeA C-terminal region (domain IV) 384 447 1.3E-18 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 PANTHER PTHR10192:SF12 19 448 5.7E-174 T 16-09-2016 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 SUPERFAMILY SSF53218 215 370 5.89E-39 T 16-09-2016 IPR001453 MoaB/Mog domain Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 SUPERFAMILY SSF63867 382 447 4.32E-16 T 16-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 Spa2297_RS13850 ac0191f8c2ead9303abe72fa9fa8f501 448 Gene3D G3DSA:3.90.105.10 170 200 1.1E-18 T 16-09-2016 Spa2297_RS27645 a08e83185973d048f2096e5e4429f6da 381 PANTHER PTHR40277 17 364 4.6E-59 T 16-09-2016 Spa2297_RS27645 a08e83185973d048f2096e5e4429f6da 381 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 38 316 6.8E-30 T 16-09-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Spa2297_RS13515 b375da6acfa4e449d562dd4ac85244ac 536 PANTHER PTHR11819:SF13 9 524 3.3E-110 T 16-09-2016 Spa2297_RS13515 b375da6acfa4e449d562dd4ac85244ac 536 Pfam PF00474 Sodium:solute symporter family 40 454 1.1E-45 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS13515 b375da6acfa4e449d562dd4ac85244ac 536 PANTHER PTHR11819 9 524 3.3E-110 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 Pfam PF07730 Histidine kinase 203 270 4.0E-18 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 SUPERFAMILY SSF55874 284 404 3.41E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PIRSF PIRSF037434 1 412 3.2E-139 T 16-09-2016 IPR017205 Signal transduction histidine kinase, ChrS Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PANTHER PTHR24421:SF24 78 420 6.6E-150 T 16-09-2016 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PANTHER PTHR24421 78 420 6.6E-150 T 16-09-2016 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 6.1E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 6.1E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 6.1E-5 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS14900 5a46fc1d075e562bb6b396dad45a9b16 420 Gene3D G3DSA:3.30.565.10 284 405 7.3E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS29390 fa271f8f6a41d3fbb8f17c0b54a0c0fb 368 SUPERFAMILY SSF81606 157 359 1.57E-7 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29390 fa271f8f6a41d3fbb8f17c0b54a0c0fb 368 SMART SM00331 143 362 5.3E-33 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29390 fa271f8f6a41d3fbb8f17c0b54a0c0fb 368 PANTHER PTHR21021 111 368 1.0E-31 T 16-09-2016 Spa2297_RS29390 fa271f8f6a41d3fbb8f17c0b54a0c0fb 368 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 361 6.9E-41 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29390 fa271f8f6a41d3fbb8f17c0b54a0c0fb 368 PANTHER PTHR21021:SF19 111 368 1.0E-31 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 PANTHER PTHR21535 33 331 4.7E-55 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 Gene3D G3DSA:1.20.58.340 255 331 3.8E-27 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 SUPERFAMILY SSF144083 266 328 1.44E-19 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 SUPERFAMILY SSF143865 3 264 8.11E-64 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 33 331 3.8E-62 T 16-09-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 Gene3D G3DSA:1.20.58.340 134 253 1.1E-35 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 Gene3D G3DSA:3.30.460.20 2 133 4.8E-42 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 PANTHER PTHR21535:SF33 33 331 4.7E-55 T 16-09-2016 Spa2297_RS06485 0d7e1b99ef5ef8de662d384a6cf0f673 331 Pfam PF01544 CorA-like Mg2+ transporter protein 32 327 4.4E-64 T 16-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spa2297_RS23905 7dc0bceed64c9341e81f7e91f22d5e37 239 PANTHER PTHR23344:SF20 11 229 1.2E-51 T 16-09-2016 Spa2297_RS23905 7dc0bceed64c9341e81f7e91f22d5e37 239 Gene3D G3DSA:3.20.20.190 5 229 1.0E-45 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS23905 7dc0bceed64c9341e81f7e91f22d5e37 239 SUPERFAMILY SSF51695 11 230 2.28E-46 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS23905 7dc0bceed64c9341e81f7e91f22d5e37 239 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 223 1.2E-30 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS23905 7dc0bceed64c9341e81f7e91f22d5e37 239 PANTHER PTHR23344 11 229 1.2E-51 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS18095 f2a9c70721637c2d3ac0b7fa3171812a 166 SUPERFAMILY SSF55874 52 141 4.6E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18095 f2a9c70721637c2d3ac0b7fa3171812a 166 Pfam PF13581 Histidine kinase-like ATPase domain 27 136 2.0E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 Gene3D G3DSA:1.10.1740.10 4 109 4.4E-24 T 16-09-2016 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 SUPERFAMILY SSF88659 119 179 4.58E-13 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 Pfam PF04542 Sigma-70 region 2 26 90 3.8E-12 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 179 2.6E-21 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 PANTHER PTHR30173 3 180 1.2E-63 T 16-09-2016 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 SUPERFAMILY SSF88946 4 98 4.91E-21 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 Pfam PF08281 Sigma-70, region 4 125 175 1.7E-12 T 16-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 PANTHER PTHR30173:SF16 3 180 1.2E-63 T 16-09-2016 Spa2297_RS15445 3c2c50e02a6cc4d2e0a3abe77b706078 180 Gene3D G3DSA:1.10.10.10 122 179 1.5E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS21325 a39cd5d451c1bc1d386a6bb49ba0a483 99 SUPERFAMILY SSF47598 27 75 6.12E-9 T 16-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 Spa2297_RS21325 a39cd5d451c1bc1d386a6bb49ba0a483 99 Gene3D G3DSA:1.10.1220.10 29 71 1.3E-5 T 16-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 PANTHER PTHR11751:SF10 88 462 1.1E-103 T 16-09-2016 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 SUPERFAMILY SSF46785 21 84 1.05E-15 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 Pfam PF00155 Aminotransferase class I and II 121 403 1.0E-17 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 PANTHER PTHR11751 88 462 1.1E-103 T 16-09-2016 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 Gene3D G3DSA:3.40.640.10 139 352 8.6E-49 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 82 1.1E-13 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 Gene3D G3DSA:1.10.10.10 23 84 5.5E-20 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 SMART SM00345 23 82 7.1E-11 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 SUPERFAMILY SSF53383 101 463 5.72E-77 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 6.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS04715 f2420c9314da802d9f681645b8fed8f5 464 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 6.3E-6 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS06775 fc6cdcaef2444153781a168e2b6d1dc0 294 Gene3D G3DSA:3.90.550.10 36 233 4.7E-18 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS06775 fc6cdcaef2444153781a168e2b6d1dc0 294 Pfam PF00535 Glycosyl transferase family 2 38 158 2.1E-21 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS06775 fc6cdcaef2444153781a168e2b6d1dc0 294 SUPERFAMILY SSF53448 34 252 3.73E-40 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS06775 fc6cdcaef2444153781a168e2b6d1dc0 294 PANTHER PTHR10859 18 264 7.7E-53 T 16-09-2016 Spa2297_RS30195 2962b32f752b4e2979ba4a523e4f6eb4 193 Pfam PF13581 Histidine kinase-like ATPase domain 75 184 8.0E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30195 2962b32f752b4e2979ba4a523e4f6eb4 193 Gene3D G3DSA:3.30.565.10 91 188 2.2E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS30195 2962b32f752b4e2979ba4a523e4f6eb4 193 SUPERFAMILY SSF55874 91 187 2.88E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 Pfam PF07690 Major Facilitator Superfamily 17 332 1.5E-21 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 PANTHER PTHR23514:SF13 1 391 2.2E-131 T 16-09-2016 Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 Gene3D G3DSA:1.20.1250.20 15 179 3.9E-16 T 16-09-2016 Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 Gene3D G3DSA:1.20.1250.20 219 392 3.5E-10 T 16-09-2016 Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 PANTHER PTHR23514 1 391 2.2E-131 T 16-09-2016 Spa2297_RS25395 7f569970eb41cd7e92c605df060146ee 403 SUPERFAMILY SSF103473 13 391 1.19E-37 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS11665 b9c913c083fe4156833bf6d1858e69e4 172 SUPERFAMILY SSF47598 109 161 4.13E-11 T 16-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 Spa2297_RS11665 b9c913c083fe4156833bf6d1858e69e4 172 Gene3D G3DSA:1.10.1220.10 111 152 2.7E-9 T 16-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Spa2297_RS11665 b9c913c083fe4156833bf6d1858e69e4 172 Pfam PF05534 HicB family 113 143 8.4E-5 T 16-09-2016 IPR008651 Uncharacterised protein family HicB Spa2297_RS05430 7bec1500f10741769e95ed6e8b7ca111 214 Pfam PF04973 Nicotinamide mononucleotide transporter 18 198 1.1E-43 T 16-09-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 Spa2297_RS05430 7bec1500f10741769e95ed6e8b7ca111 214 PANTHER PTHR36122:SF1 2 213 8.1E-94 T 16-09-2016 Spa2297_RS05430 7bec1500f10741769e95ed6e8b7ca111 214 PANTHER PTHR36122 2 213 8.1E-94 T 16-09-2016 Spa2297_RS14365 2773d0c181b341b6f9903edfe6634c45 203 PANTHER PTHR13256 11 194 2.2E-50 T 16-09-2016 Spa2297_RS14365 2773d0c181b341b6f9903edfe6634c45 203 Gene3D G3DSA:3.40.630.30 12 191 6.0E-37 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14365 2773d0c181b341b6f9903edfe6634c45 203 SUPERFAMILY SSF55729 18 190 1.92E-32 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS14365 2773d0c181b341b6f9903edfe6634c45 203 PANTHER PTHR13256:SF21 11 194 2.2E-50 T 16-09-2016 Spa2297_RS14365 2773d0c181b341b6f9903edfe6634c45 203 Pfam PF13302 Acetyltransferase (GNAT) domain 21 163 9.8E-19 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS03125 5ba13bf6903759c241c64c21f1d6d0cf 347 PANTHER PTHR19353:SF34 6 341 3.2E-136 T 16-09-2016 Spa2297_RS03125 5ba13bf6903759c241c64c21f1d6d0cf 347 PIRSF PIRSF015921 3 347 8.3E-73 T 16-09-2016 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 Spa2297_RS03125 5ba13bf6903759c241c64c21f1d6d0cf 347 Pfam PF00487 Fatty acid desaturase 65 323 1.0E-38 T 16-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 Spa2297_RS03125 5ba13bf6903759c241c64c21f1d6d0cf 347 PANTHER PTHR19353 6 341 3.2E-136 T 16-09-2016 Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 Pfam PF13229 Right handed beta helix region 158 309 1.9E-12 T 16-09-2016 Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SUPERFAMILY SSF51126 53 304 4.0E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SUPERFAMILY SSF51126 338 360 4.0E-27 T 16-09-2016 IPR011050 Pectin lyase fold/virulence factor Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 Gene3D G3DSA:2.160.20.10 53 357 1.4E-20 T 16-09-2016 IPR012334 Pectin lyase fold Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 207 242 1400.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 338 359 200.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 290 327 1000.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 159 181 230.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 243 265 13.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 267 289 2100.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00710 132 157 6200.0 T 16-09-2016 IPR006626 Parallel beta-helix repeat Spa2297_RS31775 395d327be9375575fc75a7212b1230bd 506 SMART SM00722 158 312 0.0027 T 16-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain Spa2297_RS29840 548195be8ab87bb6483819005b2bba91 131 PANTHER PTHR35908:SF2 2 131 1.7E-67 T 16-09-2016 Spa2297_RS29840 548195be8ab87bb6483819005b2bba91 131 PANTHER PTHR35908 2 131 1.7E-67 T 16-09-2016 Spa2297_RS29840 548195be8ab87bb6483819005b2bba91 131 SUPERFAMILY SSF54593 8 120 7.98E-12 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS29840 548195be8ab87bb6483819005b2bba91 131 Gene3D G3DSA:3.10.180.10 8 119 6.4E-12 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS01610 9536f8840dd2873dc9e2e0dd2bfd2aaa 143 Gene3D G3DSA:2.60.120.10 36 121 1.7E-7 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS01610 9536f8840dd2873dc9e2e0dd2bfd2aaa 143 SUPERFAMILY SSF51182 43 123 9.58E-11 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 Gene3D G3DSA:1.10.10.10 80 139 4.0E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 Gene3D G3DSA:1.10.1740.10 2 77 1.4E-10 T 16-09-2016 Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 PANTHER PTHR30173 1 145 4.2E-17 T 16-09-2016 Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 Pfam PF04542 Sigma-70 region 2 2 57 2.7E-11 T 16-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 138 2.0E-12 T 16-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 SUPERFAMILY SSF88659 65 140 6.87E-6 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS04650 1293fdf974c60ee17103303f8b666617 149 SUPERFAMILY SSF88946 2 70 5.49E-11 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS07630 37c691c3b201b0e8232e2c68b6eb0f6d 139 PANTHER PTHR41553:SF1 1 139 1.4E-45 T 16-09-2016 Spa2297_RS07630 37c691c3b201b0e8232e2c68b6eb0f6d 139 PANTHER PTHR41553 1 139 1.4E-45 T 16-09-2016 Spa2297_RS07630 37c691c3b201b0e8232e2c68b6eb0f6d 139 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 18 133 3.3E-34 T 16-09-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III Spa2297_RS07630 37c691c3b201b0e8232e2c68b6eb0f6d 139 Gene3D G3DSA:1.20.1250.20 42 113 3.1E-4 T 16-09-2016 Spa2297_RS06200 862d856c0911ed841fe470ad15bfefb5 400 Gene3D G3DSA:3.20.20.10 115 275 1.8E-5 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS06200 862d856c0911ed841fe470ad15bfefb5 400 SUPERFAMILY SSF51419 26 272 1.41E-19 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS06200 862d856c0911ed841fe470ad15bfefb5 400 Pfam PF01168 Alanine racemase, N-terminal domain 25 273 6.5E-15 T 16-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS09265 8aa1e3a121c6e93bf86bde5b1d4e916d 169 Gene3D G3DSA:1.25.40.10 40 147 2.1E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09265 8aa1e3a121c6e93bf86bde5b1d4e916d 169 SUPERFAMILY SSF48452 37 148 4.09E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS09265 8aa1e3a121c6e93bf86bde5b1d4e916d 169 Pfam PF12688 Tetratrico peptide repeat 45 164 1.3E-53 T 16-09-2016 Spa2297_RS08335 a112cd7e5871c2367773f3a6e3373e8b 211 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 131 1.8E-6 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS08335 a112cd7e5871c2367773f3a6e3373e8b 211 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 8.3E-38 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS08335 a112cd7e5871c2367773f3a6e3373e8b 211 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 2.4E-80 T 16-09-2016 IPR017519 Conserved hypothetical protein CHP03085 Spa2297_RS08335 a112cd7e5871c2367773f3a6e3373e8b 211 SUPERFAMILY SSF109854 13 114 5.04E-7 T 16-09-2016 Spa2297_RS24085 ce1b49b4a27d6ef6d37e77ce77a99186 382 Pfam PF09594 Protein of unknown function (DUF2029) 158 335 1.9E-7 T 16-09-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 Spa2297_RS16090 bfca752f840e18a8f1d19a977c57ff72 162 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 71 144 7.0E-9 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS16090 bfca752f840e18a8f1d19a977c57ff72 162 SUPERFAMILY SSF55399 49 153 3.92E-28 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS16090 bfca752f840e18a8f1d19a977c57ff72 162 Pfam PF00720 Subtilisin inhibitor-like 54 133 2.5E-11 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS16090 bfca752f840e18a8f1d19a977c57ff72 162 Gene3D G3DSA:3.30.350.10 52 152 6.6E-33 T 16-09-2016 IPR023549 Subtilisin inhibitor GO:0004867 Spa2297_RS24465 b7997c53236fd476b39875d18de787ef 150 SUPERFAMILY SSF101386 45 95 4.49E-9 T 16-09-2016 Spa2297_RS24465 b7997c53236fd476b39875d18de787ef 150 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 17 99 6.0E-23 T 16-09-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 Spa2297_RS24465 b7997c53236fd476b39875d18de787ef 150 Gene3D G3DSA:1.10.3420.10 10 136 1.4E-38 T 16-09-2016 IPR023292 NTP pyrophosphohydrolase-like domain Spa2297_RS24135 0f94d0dd49885d3b73f6055d0a2c55e8 302 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 41 287 2.0E-76 T 16-09-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 Spa2297_RS24135 0f94d0dd49885d3b73f6055d0a2c55e8 302 SUPERFAMILY SSF56112 45 276 2.14E-8 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 PANTHER PTHR32125 22 174 2.2E-31 T 16-09-2016 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 SUPERFAMILY SSF69765 20 174 5.36E-49 T 16-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 55 70 - T 16-09-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 22 172 4.6E-43 T 16-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 Pfam PF02542 YgbB family 22 171 2.9E-45 T 16-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 Gene3D G3DSA:3.30.1330.50 20 173 3.0E-53 T 16-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS15080 b94278a0d0f9cf3a2ff6b6ac8158a102 177 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 20 173 30.595 T 16-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 Spa2297_RS27860 37b2ea362e9afb3b5cfc8bf6ba6011e8 349 Pfam PF10708 Protein of unknown function (DUF2510) 7 43 4.1E-9 T 16-09-2016 IPR018929 Domain of unknown function DUF2510 Spa2297_RS21935 266aa2f53a9fad43054d0cf5d6f76088 198 Pfam PF01863 Protein of unknown function DUF45 105 180 4.8E-23 T 16-09-2016 IPR002725 Protein of unknown function DUF45 Spa2297_RS21935 266aa2f53a9fad43054d0cf5d6f76088 198 PANTHER PTHR30399:SF3 37 198 1.7E-49 T 16-09-2016 Spa2297_RS21935 266aa2f53a9fad43054d0cf5d6f76088 198 PANTHER PTHR30399 37 198 1.7E-49 T 16-09-2016 Spa2297_RS12275 7b6f7eba95e30c5993a5410bd8d02bab 424 Gene3D G3DSA:1.10.260.40 9 78 3.1E-4 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18250 afc2aab5754ffc0e059d1b1b097f75d6 401 PANTHER PTHR24421 50 399 2.7E-91 T 16-09-2016 Spa2297_RS18250 afc2aab5754ffc0e059d1b1b097f75d6 401 Gene3D G3DSA:3.30.565.10 302 399 2.1E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18250 afc2aab5754ffc0e059d1b1b097f75d6 401 SUPERFAMILY SSF55874 274 397 2.87E-17 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18250 afc2aab5754ffc0e059d1b1b097f75d6 401 Pfam PF07730 Histidine kinase 190 255 7.4E-21 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS18250 afc2aab5754ffc0e059d1b1b097f75d6 401 PANTHER PTHR24421:SF26 50 399 2.7E-91 T 16-09-2016 Spa2297_RS32675 44ab0a712c19763f5b35477b24c6e709 276 Gene3D G3DSA:2.120.10.10 18 253 8.6E-17 T 16-09-2016 IPR011040 Sialidases Spa2297_RS32675 44ab0a712c19763f5b35477b24c6e709 276 PANTHER PTHR38792 3 267 1.8E-23 T 16-09-2016 Spa2297_RS32675 44ab0a712c19763f5b35477b24c6e709 276 SUPERFAMILY SSF50939 18 232 1.5E-16 T 16-09-2016 IPR011040 Sialidases Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 1.1E-57 T 16-09-2016 IPR000037 SsrA-binding protein GO:0003723 Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 1.0E-68 T 16-09-2016 IPR000037 SsrA-binding protein GO:0003723 Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 SUPERFAMILY SSF74982 3 133 1.16E-52 T 16-09-2016 IPR023620 Small protein B Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 16-09-2016 IPR020081 SsrA-binding protein, conserved site Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 PANTHER PTHR30308 1 156 1.5E-80 T 16-09-2016 Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 Pfam PF01668 SmpB protein 9 72 3.4E-30 T 16-09-2016 IPR000037 SsrA-binding protein GO:0003723 Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 PANTHER PTHR30308:SF2 1 156 1.5E-80 T 16-09-2016 Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 Gene3D G3DSA:2.40.280.10 8 128 1.6E-52 T 16-09-2016 IPR023620 Small protein B Spa2297_RS12820 b2f442ce9b69f25af5699dff47c30fdb 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 73.163 T 16-09-2016 IPR000037 SsrA-binding protein GO:0003723 Spa2297_RS34380 65a4d6de3bb41b0e5a2a62ce981e2a57 72 PANTHER PTHR37489:SF2 3 72 5.1E-18 T 16-09-2016 Spa2297_RS34380 65a4d6de3bb41b0e5a2a62ce981e2a57 72 Pfam PF12006 Protein of unknown function (DUF3500) 15 70 5.3E-9 T 16-09-2016 IPR021889 Protein of unknown function DUF3500 Spa2297_RS34380 65a4d6de3bb41b0e5a2a62ce981e2a57 72 PANTHER PTHR37489 3 72 5.1E-18 T 16-09-2016 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 PANTHER PTHR21021 282 576 1.2E-62 T 16-09-2016 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 Gene3D G3DSA:3.30.450.40 196 334 1.8E-14 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 SUPERFAMILY SSF81606 372 562 3.66E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 PANTHER PTHR21021:SF19 282 576 1.2E-62 T 16-09-2016 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 383 572 1.7E-49 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 SMART SM00331 354 573 1.7E-32 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02080 c507f347d1f8fe221c4af7bdaa3945f4 577 SUPERFAMILY SSF55781 228 338 5.67E-9 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS15640 8937a0d79d70b760827cb3753155d545 469 Pfam PF13367 Protease prsW family 84 282 1.6E-48 T 16-09-2016 IPR026898 Protease PrsW GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS15640 8937a0d79d70b760827cb3753155d545 469 PANTHER PTHR36844 4 425 3.5E-59 T 16-09-2016 Spa2297_RS11595 43711c86804c779e4310fd55bc89b5c3 175 Pfam PF06353 Protein of unknown function (DUF1062) 29 158 7.4E-36 T 16-09-2016 IPR009412 Protein of unknown function DUF1062 Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 SMART SM00854 46 295 1.7E-75 T 16-09-2016 IPR019079 Capsule synthesis protein, CapA Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 46 293 8.6E-65 T 16-09-2016 IPR019079 Capsule synthesis protein, CapA Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 PANTHER PTHR33393:SF2 3 303 3.7E-56 T 16-09-2016 Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 Gene3D G3DSA:3.60.21.10 102 290 3.0E-16 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 PANTHER PTHR33393 3 303 3.7E-56 T 16-09-2016 Spa2297_RS28950 657341f765f037aebd2c107b95bdf250 384 SUPERFAMILY SSF56300 46 350 2.33E-32 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 56 165 1.2E-23 T 16-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 SUPERFAMILY SSF56770 35 176 4.97E-61 T 16-09-2016 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 PANTHER PTHR11995 19 180 2.3E-96 T 16-09-2016 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 Gene3D G3DSA:3.40.50.700 39 171 2.4E-36 T 16-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 6 170 40.137 T 16-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 PANTHER PTHR11995:SF14 19 180 2.3E-96 T 16-09-2016 Spa2297_RS19450 85ef510eedfb78c975d12a84dd38191f 259 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 35 171 5.5E-66 T 16-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Spa2297_RS27630 3c05b79b04d8640fbf8210bca016f976 132 PANTHER PTHR12589 1 130 4.4E-74 T 16-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Spa2297_RS27630 3c05b79b04d8640fbf8210bca016f976 132 Gene3D G3DSA:3.30.479.10 2 130 1.4E-41 T 16-09-2016 Spa2297_RS27630 3c05b79b04d8640fbf8210bca016f976 132 PANTHER PTHR12589:SF4 1 130 4.4E-74 T 16-09-2016 Spa2297_RS27630 3c05b79b04d8640fbf8210bca016f976 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 4.4E-21 T 16-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Spa2297_RS27630 3c05b79b04d8640fbf8210bca016f976 132 SUPERFAMILY SSF55620 2 129 1.17E-27 T 16-09-2016 Spa2297_RS12550 10f3828de7710e49a0833c4d8b9e9529 294 Gene3D G3DSA:1.10.3720.10 64 282 1.5E-29 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12550 10f3828de7710e49a0833c4d8b9e9529 294 PANTHER PTHR30177:SF4 10 292 6.2E-126 T 16-09-2016 Spa2297_RS12550 10f3828de7710e49a0833c4d8b9e9529 294 SUPERFAMILY SSF161098 91 277 2.09E-35 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12550 10f3828de7710e49a0833c4d8b9e9529 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 280 7.6E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12550 10f3828de7710e49a0833c4d8b9e9529 294 PANTHER PTHR30177 10 292 6.2E-126 T 16-09-2016 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 PANTHER PTHR10668:SF83 22 536 5.9E-145 T 16-09-2016 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 PANTHER PTHR10668 22 536 5.9E-145 T 16-09-2016 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 Pfam PF01593 Flavin containing amine oxidoreductase 36 321 1.3E-11 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 SUPERFAMILY SSF51905 22 336 9.88E-34 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 Gene3D G3DSA:3.50.50.60 23 91 4.1E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS02465 d8750d980ce1543b438b886960d16fac 536 Gene3D G3DSA:3.50.50.60 226 316 4.1E-30 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS03310 4e376cf79f742e79a41e06f8a6cb77ee 153 Pfam PF00932 Lamin Tail Domain 31 145 5.0E-15 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS03310 4e376cf79f742e79a41e06f8a6cb77ee 153 SUPERFAMILY SSF74853 29 140 2.88E-16 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS03310 4e376cf79f742e79a41e06f8a6cb77ee 153 Gene3D G3DSA:2.60.40.1260 35 139 5.5E-13 T 16-09-2016 IPR001322 Lamin Tail Domain Spa2297_RS20250 05298005ce6c3f4c9d7be27db56f1d65 548 SUPERFAMILY SSF51261 418 540 1.52E-40 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS20250 05298005ce6c3f4c9d7be27db56f1d65 548 Gene3D G3DSA:2.70.70.10 396 541 1.1E-40 T 16-09-2016 Spa2297_RS20250 05298005ce6c3f4c9d7be27db56f1d65 548 Pfam PF01551 Peptidase family M23 442 536 4.9E-28 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS20250 05298005ce6c3f4c9d7be27db56f1d65 548 PANTHER PTHR21666 381 546 5.0E-39 T 16-09-2016 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PANTHER PTHR10353 9 451 1.7E-198 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 TIGRFAM TIGR03356 BGL: beta-galactosidase 9 437 2.8E-186 T 16-09-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 Gene3D G3DSA:3.20.20.80 8 448 6.8E-156 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 12 26 - T 16-09-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 SUPERFAMILY SSF51445 8 445 6.95E-158 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PANTHER PTHR10353:SF36 9 451 1.7E-198 T 16-09-2016 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 286 300 1.0E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 381 1.0E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 408 1.0E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 349 357 1.0E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 427 1.0E-20 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS27545 e8aae491cd6964cba5b43d2ade384e91 452 Pfam PF00232 Glycosyl hydrolase family 1 7 444 1.2E-152 T 16-09-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spa2297_RS02795 82b80760072770efe1fff7634d55929f 155 PANTHER PTHR34310:SF2 3 155 8.4E-70 T 16-09-2016 Spa2297_RS02795 82b80760072770efe1fff7634d55929f 155 Pfam PF04248 Domain of unknown function (DUF427) 21 113 8.8E-35 T 16-09-2016 IPR007361 Domain of unknown function DUF427 Spa2297_RS02795 82b80760072770efe1fff7634d55929f 155 PANTHER PTHR34310 3 155 8.4E-70 T 16-09-2016 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 192 37.158 T 16-09-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 190 2.1E-81 T 16-09-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 16-09-2016 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 Pfam PF01174 SNO glutamine amidotransferase family 9 193 1.8E-58 T 16-09-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 Gene3D G3DSA:3.40.50.880 4 199 1.1E-77 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 PANTHER PTHR31559:SF0 1 198 5.1E-92 T 16-09-2016 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 PIRSF PIRSF005639 1 197 1.1E-73 T 16-09-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 PANTHER PTHR31559 1 198 5.1E-92 T 16-09-2016 Spa2297_RS05770 19afca3980927d1f20fbda1cc7f02fd4 201 SUPERFAMILY SSF52317 6 194 9.67E-53 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS12295 7700d5632a358b72cea10150f24f1bc7 538 Gene3D G3DSA:3.30.565.10 251 360 4.1E-7 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS12295 7700d5632a358b72cea10150f24f1bc7 538 SUPERFAMILY SSF55874 248 358 3.3E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS00120 c709d67c49fb4ffa5b887699ce077ade 122 Gene3D G3DSA:3.10.180.10 7 119 1.2E-19 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00120 c709d67c49fb4ffa5b887699ce077ade 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 3.9E-10 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS00120 c709d67c49fb4ffa5b887699ce077ade 122 SUPERFAMILY SSF54593 1 119 6.18E-23 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS31595 468500360146820634306c59b7e7992a 303 SUPERFAMILY SSF89392 68 280 3.69E-12 T 16-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 SUPERFAMILY SSF53067 2 103 1.21E-23 T 16-09-2016 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 Gene3D G3DSA:3.30.420.40 2 126 1.4E-37 T 16-09-2016 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 SUPERFAMILY SSF53067 107 199 1.81E-12 T 16-09-2016 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 201 5.2E-57 T 16-09-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 PANTHER PTHR11735 1 143 1.9E-40 T 16-09-2016 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 Pfam PF00814 Glycoprotease family 32 145 1.7E-30 T 16-09-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 Spa2297_RS20025 486583463c3e2c76b10b8ddedbe84658 217 PANTHER PTHR11735:SF11 1 143 1.9E-40 T 16-09-2016 Spa2297_RS11810 f7fd31f7e8e75cdf9f7ece897e0e165b 293 Pfam PF14472 Domain of unknown function (DUF4429) 11 105 1.5E-17 T 16-09-2016 IPR027860 Domain of unknown function DUF4429 Spa2297_RS11810 f7fd31f7e8e75cdf9f7ece897e0e165b 293 Pfam PF14472 Domain of unknown function (DUF4429) 139 225 1.4E-22 T 16-09-2016 IPR027860 Domain of unknown function DUF4429 Spa2297_RS11810 f7fd31f7e8e75cdf9f7ece897e0e165b 293 Pfam PF09851 Short C-terminal domain 264 290 2.2E-6 T 16-09-2016 IPR018649 SHOCT domain Spa2297_RS05700 43313e553500d791adcba8f6c98c777a 220 PANTHER PTHR34573:SF2 1 220 5.8E-64 T 16-09-2016 Spa2297_RS05700 43313e553500d791adcba8f6c98c777a 220 PANTHER PTHR34573 1 220 5.8E-64 T 16-09-2016 Spa2297_RS05700 43313e553500d791adcba8f6c98c777a 220 SMART SM00756 30 175 1.1E-55 T 16-09-2016 IPR012932 Vitamin K epoxide reductase Spa2297_RS05700 43313e553500d791adcba8f6c98c777a 220 Pfam PF07884 Vitamin K epoxide reductase family 36 171 7.9E-27 T 16-09-2016 IPR012932 Vitamin K epoxide reductase Spa2297_RS18325 8b3d84071afa52eeaf0b928f4fd27d0d 111 Pfam PF11774 Lsr2 2 109 7.0E-40 T 16-09-2016 IPR024412 Lsr2 Spa2297_RS18325 8b3d84071afa52eeaf0b928f4fd27d0d 111 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 6.0E-39 T 16-09-2016 IPR024412 Lsr2 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 PANTHER PTHR11647 1 461 1.1E-209 T 16-09-2016 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 Gene3D G3DSA:2.30.40.10 4 74 1.1E-27 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 PANTHER PTHR11647:SF1 1 461 1.1E-209 T 16-09-2016 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 Pfam PF01979 Amidohydrolase family 56 441 1.3E-26 T 16-09-2016 IPR006680 Amidohydrolase-related GO:0016787 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 459 1.0E-170 T 16-09-2016 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: REACT_18266 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 Gene3D G3DSA:2.30.40.10 383 457 2.7E-14 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 Gene3D G3DSA:3.20.20.140 75 382 2.9E-116 T 16-09-2016 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 SUPERFAMILY SSF51338 5 71 5.4E-9 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 SUPERFAMILY SSF51556 60 388 1.16E-106 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS26770 9191e4604d0d1676b495f610cab1b003 467 SUPERFAMILY SSF51338 364 462 7.14E-33 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 409 431 4.6E-35 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 SUPERFAMILY SSF52540 289 359 1.39E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 SUPERFAMILY SSF52540 392 510 1.39E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 SUPERFAMILY SSF52540 144 342 1.77E-32 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 539 2.4E-47 T 16-09-2016 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 SMART SM00490 422 499 2.1E-12 T 16-09-2016 IPR001650 Helicase, C-terminal Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 Gene3D G3DSA:3.40.50.300 180 342 2.3E-28 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 PANTHER PTHR11274 4 544 1.3E-187 T 16-09-2016 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 Pfam PF04851 Type III restriction enzyme, res subunit 181 325 1.6E-13 T 16-09-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 Pfam PF13625 Helicase conserved C-terminal domain 5 133 4.2E-46 T 16-09-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 Gene3D G3DSA:3.40.50.300 381 528 3.5E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS14695 a5350f72d25eb7484f7469b2dc8ad236 548 SMART SM00487 177 352 2.2E-21 T 16-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spa2297_RS28405 999ee89f739626463278a9b771922e5e 265 PANTHER PTHR30269 9 264 6.2E-143 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS28405 999ee89f739626463278a9b771922e5e 265 PANTHER PTHR30269:SF24 9 264 6.2E-143 T 16-09-2016 Spa2297_RS28405 999ee89f739626463278a9b771922e5e 265 Pfam PF01925 Sulfite exporter TauE/SafE 17 261 6.3E-27 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS14710 fedde1c1825828c55c300d74a0bb7bcb 229 SUPERFAMILY SSF110395 6 228 2.48E-46 T 16-09-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Spa2297_RS14710 fedde1c1825828c55c300d74a0bb7bcb 229 Gene3D G3DSA:3.20.20.380 5 210 4.0E-49 T 16-09-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Spa2297_RS14710 fedde1c1825828c55c300d74a0bb7bcb 229 PANTHER PTHR12598:SF0 1 211 5.5E-54 T 16-09-2016 Spa2297_RS14710 fedde1c1825828c55c300d74a0bb7bcb 229 Pfam PF03932 CutC family 6 202 1.7E-25 T 16-09-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Spa2297_RS14710 fedde1c1825828c55c300d74a0bb7bcb 229 PANTHER PTHR12598 1 211 5.5E-54 T 16-09-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 SUPERFAMILY SSF46689 26 110 4.59E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 84 7.6E-13 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 PANTHER PTHR30055:SF49 20 227 6.5E-65 T 16-09-2016 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 Gene3D G3DSA:1.10.357.10 28 213 2.1E-43 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 7.8E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 7.8E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 PANTHER PTHR30055 20 227 6.5E-65 T 16-09-2016 Spa2297_RS13965 f9f4f1ace7b906509143a9ac3395b473 231 SUPERFAMILY SSF48498 104 212 1.15E-30 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 Pfam PF13692 Glycosyl transferases group 1 312 469 1.8E-22 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 SUPERFAMILY SSF53756 193 501 1.75E-54 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 SUPERFAMILY SSF53756 2 89 1.75E-54 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 PANTHER PTHR12526 2 42 2.4E-43 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 PANTHER PTHR12526 160 514 2.4E-43 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 Gene3D G3DSA:3.40.50.2000 306 482 2.1E-18 T 16-09-2016 Spa2297_RS21840 e8d3803db983d426539973b8a526ea09 571 Pfam PF11997 Domain of unknown function (DUF3492) 2 284 1.8E-28 T 16-09-2016 IPR022622 Domain of unknown function DUF3492 Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 SUPERFAMILY SSF50129 1 147 2.43E-32 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 Pfam PF13602 Zinc-binding dehydrogenase 195 299 7.8E-15 T 16-09-2016 Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 SMART SM00829 10 299 1.1E-13 T 16-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 PANTHER PTHR11695:SF294 15 301 3.8E-66 T 16-09-2016 Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 Gene3D G3DSA:3.90.180.10 1 185 5.6E-48 T 16-09-2016 IPR011032 GroES-like Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 PANTHER PTHR11695 15 301 3.8E-66 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 SUPERFAMILY SSF51735 114 298 1.67E-22 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS31910 3cae963b2714507ab26bfdaf95857658 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 4.5E-10 T 16-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spa2297_RS30340 8fa32fc98f6e35fbfbe3cfe749f5c761 205 Gene3D G3DSA:1.10.357.10 4 199 1.2E-28 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS30340 8fa32fc98f6e35fbfbe3cfe749f5c761 205 PANTHER PTHR30055 3 201 9.3E-76 T 16-09-2016 Spa2297_RS30340 8fa32fc98f6e35fbfbe3cfe749f5c761 205 PANTHER PTHR30055:SF64 3 201 9.3E-76 T 16-09-2016 Spa2297_RS30340 8fa32fc98f6e35fbfbe3cfe749f5c761 205 SUPERFAMILY SSF46689 17 71 5.99E-12 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS30340 8fa32fc98f6e35fbfbe3cfe749f5c761 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 5.0E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 SUPERFAMILY SSF53335 166 298 6.72E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 234 240 - T 16-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 Pfam PF05175 Methyltransferase small domain 165 281 5.8E-12 T 16-09-2016 IPR007848 Methyltransferase small domain GO:0008168 Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 PANTHER PTHR18895 169 350 4.7E-42 T 16-09-2016 Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 PANTHER PTHR18895:SF64 169 350 4.7E-42 T 16-09-2016 Spa2297_RS17985 32341599c9e6ca47bd55115308146c8c 504 Gene3D G3DSA:3.40.50.150 153 307 4.9E-27 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PANTHER PTHR19370 14 239 1.2E-62 T 16-09-2016 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 122 141 9.6E-7 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 63 77 9.6E-7 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 206 214 9.6E-7 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PRINTS PR00409 Phthalate dioxygenase reductase family signature 100 114 9.6E-7 T 16-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 SUPERFAMILY SSF52343 113 238 8.91E-24 T 16-09-2016 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 Gene3D G3DSA:3.40.50.80 116 239 1.5E-18 T 16-09-2016 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 Pfam PF00970 Oxidoreductase FAD-binding domain 18 112 1.2E-13 T 16-09-2016 IPR008333 Oxidoreductase, FAD-binding domain Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 PANTHER PTHR19370:SF123 14 239 1.2E-62 T 16-09-2016 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 SUPERFAMILY SSF63380 14 116 5.48E-27 T 16-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 Spa2297_RS03080 76f17dc7702575be0f9e1059447f6ec7 239 Gene3D G3DSA:2.40.30.10 15 109 2.9E-23 T 16-09-2016 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 PANTHER PTHR33164 14 130 1.2E-20 T 16-09-2016 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 109 - T 16-09-2016 IPR023187 Transcriptional regulator MarR-type, conserved site Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 3.6E-8 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 3.6E-8 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 3.6E-8 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 Pfam PF12802 MarR family 36 100 2.5E-13 T 16-09-2016 Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 Gene3D G3DSA:1.10.10.10 14 129 2.0E-31 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 SUPERFAMILY SSF46785 14 129 8.24E-27 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS03535 b4bc7130f1871fc776fb8be2a3b01927 130 SMART SM00347 30 130 1.0E-17 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 Pfam PF01061 ABC-2 type transporter 13 226 4.9E-28 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PIRSF PIRSF006648 2 261 1.5E-65 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 107 132 1.9E-6 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 64 86 1.9E-6 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 1.9E-6 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 203 1.9E-6 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PANTHER PTHR30294:SF24 3 262 1.8E-109 T 16-09-2016 Spa2297_RS14180 2544c034127b7434f6268dd73050f706 262 PANTHER PTHR30294 3 262 1.8E-109 T 16-09-2016 Spa2297_RS11465 09992016d923907e29a6b305706bbef9 229 Gene3D G3DSA:3.20.20.370 52 189 1.2E-28 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS11465 09992016d923907e29a6b305706bbef9 229 Pfam PF01522 Polysaccharide deacetylase 49 183 3.4E-28 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS11465 09992016d923907e29a6b305706bbef9 229 PANTHER PTHR34216 1 226 4.3E-65 T 16-09-2016 Spa2297_RS11465 09992016d923907e29a6b305706bbef9 229 SUPERFAMILY SSF88713 13 185 8.9E-38 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 PANTHER PTHR12526 2 80 3.5E-58 T 16-09-2016 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 PANTHER PTHR12526 108 417 3.5E-58 T 16-09-2016 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 Pfam PF00534 Glycosyl transferases group 1 200 354 2.7E-40 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 Gene3D G3DSA:3.40.50.2000 200 356 1.9E-23 T 16-09-2016 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 SUPERFAMILY SSF53756 90 376 7.85E-66 T 16-09-2016 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 SUPERFAMILY SSF53756 2 59 7.85E-66 T 16-09-2016 Spa2297_RS10950 f03ae87e9b3dc60c4b86720d2e17a0ab 679 Pfam PF13439 Glycosyltransferase Family 4 13 192 2.6E-7 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS13175 4aa9de29d4d2d2ef4252b59339833a61 380 PANTHER PTHR33392:SF7 8 350 1.9E-128 T 16-09-2016 Spa2297_RS13175 4aa9de29d4d2d2ef4252b59339833a61 380 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 108 263 2.2E-46 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13175 4aa9de29d4d2d2ef4252b59339833a61 380 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 108 263 1.3E-44 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13175 4aa9de29d4d2d2ef4252b59339833a61 380 PANTHER PTHR33392 8 350 1.9E-128 T 16-09-2016 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 PRINTS PR01399 Enterobactin synthetase component D signature 146 162 1.1E-26 T 16-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 PRINTS PR01399 Enterobactin synthetase component D signature 39 59 1.1E-26 T 16-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 PRINTS PR01399 Enterobactin synthetase component D signature 69 87 1.1E-26 T 16-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 SUPERFAMILY SSF56214 102 222 6.63E-14 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 Gene3D G3DSA:3.90.470.20 119 199 2.5E-5 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 103 178 2.4E-10 T 16-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 Spa2297_RS27740 c41a6b863bba4c03f56af98cee8db5f1 226 PANTHER PTHR38096 4 225 8.0E-69 T 16-09-2016 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 Gene3D G3DSA:1.10.260.40 3 81 5.1E-14 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 SMART SM00530 6 82 1.1E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 PANTHER PTHR35010:SF2 1 292 4.1E-83 T 16-09-2016 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 PANTHER PTHR35010 1 292 4.1E-83 T 16-09-2016 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 Pfam PF13560 Helix-turn-helix domain 30 85 1.2E-13 T 16-09-2016 Spa2297_RS03265 67f07bdd7221146ae472f9b71e3b8086 295 SUPERFAMILY SSF47413 30 79 9.78E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 Gene3D G3DSA:3.40.50.300 190 396 1.2E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 Gene3D G3DSA:3.30.450.90 84 182 1.3E-14 T 16-09-2016 Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 Pfam PF00437 Type II/IV secretion system protein 89 371 2.3E-44 T 16-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 PANTHER PTHR30258 35 403 7.5E-87 T 16-09-2016 Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 SUPERFAMILY SSF52540 67 373 9.11E-40 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS19035 7d502a0e53ee1166ced1e2fab01d86e1 435 PANTHER PTHR30258:SF3 35 403 7.5E-87 T 16-09-2016 Spa2297_RS07950 a574bbcb6159fb878be4b1c3e223701f 297 PANTHER PTHR23344 26 290 4.5E-80 T 16-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 Spa2297_RS07950 a574bbcb6159fb878be4b1c3e223701f 297 SUPERFAMILY SSF51695 34 287 5.23E-69 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS07950 a574bbcb6159fb878be4b1c3e223701f 297 Gene3D G3DSA:3.20.20.190 18 289 1.4E-75 T 16-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 Spa2297_RS07950 a574bbcb6159fb878be4b1c3e223701f 297 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 40 282 3.1E-41 T 16-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spa2297_RS07950 a574bbcb6159fb878be4b1c3e223701f 297 PANTHER PTHR23344:SF20 26 290 4.5E-80 T 16-09-2016 Spa2297_RS07765 a168b854c1c6ec8d24d43c55ec4433f9 262 SUPERFAMILY SSF110710 9 258 9.42E-86 T 16-09-2016 Spa2297_RS07765 a168b854c1c6ec8d24d43c55ec4433f9 262 PANTHER PTHR11104 1 261 5.6E-91 T 16-09-2016 Spa2297_RS07765 a168b854c1c6ec8d24d43c55ec4433f9 262 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 32 255 1.2E-73 T 16-09-2016 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 PANTHER PTHR11732:SF136 20 307 1.1E-124 T 16-09-2016 Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 SUPERFAMILY SSF51430 27 307 2.49E-56 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 Pfam PF00248 Aldo/keto reductase family 32 306 2.9E-42 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 Gene3D G3DSA:3.20.20.100 27 309 2.0E-55 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 PRINTS PR00069 Aldo-keto reductase signature 57 81 1.7E-9 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 PRINTS PR00069 Aldo-keto reductase signature 241 265 1.7E-9 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 PRINTS PR00069 Aldo-keto reductase signature 167 184 1.7E-9 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS31370 84451cc2847f2472e7dd5e65b24f712c 317 PANTHER PTHR11732 20 307 1.1E-124 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS03120 a51cac8170a4123ff08a78444e730ae2 393 PANTHER PTHR21581:SF1 70 335 3.4E-63 T 16-09-2016 Spa2297_RS03120 a51cac8170a4123ff08a78444e730ae2 393 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 70 299 6.2E-30 T 16-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Spa2297_RS03120 a51cac8170a4123ff08a78444e730ae2 393 PANTHER PTHR21581 70 335 3.4E-63 T 16-09-2016 Spa2297_RS03120 a51cac8170a4123ff08a78444e730ae2 393 SUPERFAMILY SSF56601 63 319 1.11E-48 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS03120 a51cac8170a4123ff08a78444e730ae2 393 Gene3D G3DSA:3.40.710.10 69 320 7.7E-63 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS07780 2f0d8247520ad4da50c0c72111640202 336 PANTHER PTHR35457:SF1 8 331 6.8E-65 T 16-09-2016 Spa2297_RS07780 2f0d8247520ad4da50c0c72111640202 336 PANTHER PTHR35457 8 331 6.8E-65 T 16-09-2016 Spa2297_RS07780 2f0d8247520ad4da50c0c72111640202 336 Pfam PF02628 Cytochrome oxidase assembly protein 84 304 3.4E-10 T 16-09-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 Spa2297_RS07780 2f0d8247520ad4da50c0c72111640202 336 Pfam PF02628 Cytochrome oxidase assembly protein 36 78 1.7E-10 T 16-09-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 Spa2297_RS22810 26c6cf060cc1354cbdb39d560cf3fe7e 310 PANTHER PTHR23242:SF11 1 307 1.3E-92 T 16-09-2016 Spa2297_RS22810 26c6cf060cc1354cbdb39d560cf3fe7e 310 Gene3D G3DSA:1.20.1170.10 25 126 4.9E-4 T 16-09-2016 Spa2297_RS22810 26c6cf060cc1354cbdb39d560cf3fe7e 310 PANTHER PTHR23242 1 307 1.3E-92 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 402 1.6E-52 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 SUPERFAMILY SSF56645 5 234 1.44E-57 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 PANTHER PTHR10909:SF121 249 408 1.8E-124 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 PANTHER PTHR10909:SF121 1 232 1.8E-124 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 6.9E-15 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 SUPERFAMILY SSF47203 258 406 2.74E-54 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.2E-24 T 16-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Gene3D G3DSA:2.40.110.10 125 222 8.2E-36 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 16-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Gene3D G3DSA:1.10.540.10 4 115 1.3E-24 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 Gene3D G3DSA:1.20.140.10 223 404 8.8E-66 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 PANTHER PTHR10909 249 408 1.8E-124 T 16-09-2016 Spa2297_RS04365 44e6019c4a1e910993ec0cb29f2d1dc4 408 PANTHER PTHR10909 1 232 1.8E-124 T 16-09-2016 Spa2297_RS09870 563f152953f0079bcd95cc44de4b3620 212 PANTHER PTHR30353 16 204 3.3E-26 T 16-09-2016 IPR032818 DedA family Spa2297_RS09870 563f152953f0079bcd95cc44de4b3620 212 Pfam PF09335 SNARE associated Golgi protein 49 171 4.0E-10 T 16-09-2016 IPR032816 SNARE associated Golgi protein Spa2297_RS10165 5bc359bee8bb4f843515490e4d96479b 171 Gene3D G3DSA:3.10.450.50 110 164 7.6E-4 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS20710 fd66728c3505a4c5ed7591dc770fc780 306 Pfam PF03547 Membrane transport protein 8 133 1.0E-10 T 16-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 Spa2297_RS20710 fd66728c3505a4c5ed7591dc770fc780 306 Pfam PF03547 Membrane transport protein 159 298 3.6E-15 T 16-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 Spa2297_RS20710 fd66728c3505a4c5ed7591dc770fc780 306 PANTHER PTHR36838 1 305 2.5E-28 T 16-09-2016 Spa2297_RS17560 60734e99339ee728a9c2715fad455cf4 312 SUPERFAMILY SSF55961 1 138 1.4E-14 T 16-09-2016 Spa2297_RS17560 60734e99339ee728a9c2715fad455cf4 312 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 139 2.7E-8 T 16-09-2016 IPR010419 Carbon monoxide dehydrogenase subunit G Spa2297_RS17560 60734e99339ee728a9c2715fad455cf4 312 Gene3D G3DSA:3.30.530.20 1 140 3.0E-20 T 16-09-2016 IPR023393 START-like domain Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SUPERFAMILY SSF69318 65 350 9.02E-28 T 16-09-2016 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SUPERFAMILY SSF69318 373 492 1.29E-12 T 16-09-2016 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 Gene3D G3DSA:2.130.10.130 66 208 3.5E-16 T 16-09-2016 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 Gene3D G3DSA:2.130.10.130 373 491 6.5E-15 T 16-09-2016 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 Pfam PF01839 FG-GAP repeat 438 463 1.2E-7 T 16-09-2016 IPR013517 FG-GAP repeat Reactome: REACT_13552 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 Pfam PF01839 FG-GAP repeat 374 405 1.4E-7 T 16-09-2016 IPR013517 FG-GAP repeat Reactome: REACT_13552 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SMART SM00191 124 175 16.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SMART SM00191 301 356 59.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SMART SM00191 366 427 28.0 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS14545 5a3290799e0d019f56764ac9c2dc065b 509 SMART SM00191 434 488 1.0E-7 T 16-09-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 Pfam PF00005 ABC transporter 41 199 8.5E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 SUPERFAMILY SSF52540 20 271 2.25E-67 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 SMART SM00382 49 249 7.5E-15 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 PANTHER PTHR24220:SF442 22 279 7.1E-130 T 16-09-2016 Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 Gene3D G3DSA:3.40.50.300 19 273 1.7E-72 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS01010 55e9415be1f69d1690e9a70f6d1e5eee 281 PANTHER PTHR24220 22 279 7.1E-130 T 16-09-2016 Spa2297_RS21265 76f3d4a6ab5a8825bf9f7158041e97cf 290 Pfam PF00296 Luciferase-like monooxygenase 13 223 2.4E-39 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS21265 76f3d4a6ab5a8825bf9f7158041e97cf 290 PANTHER PTHR30137 3 290 1.0E-50 T 16-09-2016 Spa2297_RS21265 76f3d4a6ab5a8825bf9f7158041e97cf 290 SUPERFAMILY SSF51679 5 289 7.72E-50 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS21265 76f3d4a6ab5a8825bf9f7158041e97cf 290 PANTHER PTHR30137:SF8 3 290 1.0E-50 T 16-09-2016 Spa2297_RS21265 76f3d4a6ab5a8825bf9f7158041e97cf 290 Gene3D G3DSA:3.20.20.30 10 289 9.6E-51 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS34020 e36e1606ce909b40d86e7f6c0372909e 190 PANTHER PTHR36151:SF3 1 190 2.4E-49 T 16-09-2016 Spa2297_RS34020 e36e1606ce909b40d86e7f6c0372909e 190 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 1 165 4.4E-30 T 16-09-2016 IPR018713 Domain of unknown function DUF2236 Spa2297_RS34020 e36e1606ce909b40d86e7f6c0372909e 190 PANTHER PTHR36151 1 190 2.4E-49 T 16-09-2016 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 Gene3D G3DSA:3.30.565.10 208 379 2.3E-45 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PANTHER PTHR24423:SF394 91 379 6.7E-85 T 16-09-2016 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 Gene3D G3DSA:1.10.287.130 147 207 2.5E-14 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 SMART SM00387 266 382 4.5E-37 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 SMART SM00388 155 221 3.2E-15 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PANTHER PTHR24423 91 379 6.7E-85 T 16-09-2016 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 SUPERFAMILY SSF55874 211 379 9.17E-44 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 4.3E-21 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 4.3E-21 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 4.3E-21 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 4.3E-21 T 16-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 9.1E-13 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 SUPERFAMILY SSF47384 138 221 1.24E-16 T 16-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spa2297_RS15105 c1e675f47c8226971f43b96bafd2966e 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 380 1.3E-21 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16265 47eda4a07e77605e5eda1b799e3b7a6d 301 PANTHER PTHR30011:SF14 16 247 5.6E-69 T 16-09-2016 Spa2297_RS16265 47eda4a07e77605e5eda1b799e3b7a6d 301 Pfam PF00296 Luciferase-like monooxygenase 24 238 2.3E-45 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS16265 47eda4a07e77605e5eda1b799e3b7a6d 301 Gene3D G3DSA:3.20.20.30 22 294 5.4E-61 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS16265 47eda4a07e77605e5eda1b799e3b7a6d 301 PANTHER PTHR30011 16 247 5.6E-69 T 16-09-2016 Spa2297_RS16265 47eda4a07e77605e5eda1b799e3b7a6d 301 SUPERFAMILY SSF51679 20 276 4.84E-54 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS03590 7bf7f9f6b4ccd9d0fb7676e7efa1c2bf 432 SUPERFAMILY SSF51621 101 345 3.24E-14 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS03590 7bf7f9f6b4ccd9d0fb7676e7efa1c2bf 432 PANTHER PTHR32308 97 428 2.5E-80 T 16-09-2016 IPR011206 Citrate lyase beta subunit-like Spa2297_RS03590 7bf7f9f6b4ccd9d0fb7676e7efa1c2bf 432 Gene3D G3DSA:3.20.20.60 112 304 1.1E-13 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS03590 7bf7f9f6b4ccd9d0fb7676e7efa1c2bf 432 PANTHER PTHR32308:SF0 97 428 2.5E-80 T 16-09-2016 Spa2297_RS03590 7bf7f9f6b4ccd9d0fb7676e7efa1c2bf 432 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 187 296 2.1E-7 T 16-09-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Spa2297_RS25120 98edc58717bc9190f26da6a9377818a3 480 PIRSF PIRSF006060 12 476 1.7E-90 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS25120 98edc58717bc9190f26da6a9377818a3 480 PANTHER PTHR11785 15 479 2.5E-284 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS25120 98edc58717bc9190f26da6a9377818a3 480 PANTHER PTHR11785:SF328 15 479 2.5E-284 T 16-09-2016 Spa2297_RS25120 98edc58717bc9190f26da6a9377818a3 480 Pfam PF13520 Amino acid permease 30 430 1.6E-53 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS14715 a340318dce5106ae415c79cd2c09be8e 227 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 106 5.0E-9 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS14715 a340318dce5106ae415c79cd2c09be8e 227 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 23 204 7.4E-25 T 16-09-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type Spa2297_RS14715 a340318dce5106ae415c79cd2c09be8e 227 SUPERFAMILY SSF109854 19 138 2.38E-10 T 16-09-2016 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 SUPERFAMILY SSF103481 181 282 1.57E-14 T 16-09-2016 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 SUPERFAMILY SSF103481 48 138 1.22E-11 T 16-09-2016 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 Pfam PF00892 EamA-like transporter family 145 277 7.0E-22 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 Pfam PF00892 EamA-like transporter family 9 135 4.5E-11 T 16-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 PANTHER PTHR32322 1 278 1.3E-62 T 16-09-2016 Spa2297_RS11210 aa4fffd2eb3e8fa1100871684bd1a630 319 PANTHER PTHR32322:SF2 1 278 1.3E-62 T 16-09-2016 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 SUPERFAMILY SSF50494 41 241 2.28E-35 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 112 126 8.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 194 206 8.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 67 82 8.5E-8 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 Pfam PF00089 Trypsin 49 236 2.7E-26 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 SMART SM00020 42 236 3.9E-14 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 Gene3D G3DSA:2.40.10.10 53 120 5.1E-12 T 16-09-2016 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 Gene3D G3DSA:2.40.10.10 121 239 5.1E-18 T 16-09-2016 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 PANTHER PTHR24260 16 240 3.0E-135 T 16-09-2016 Spa2297_RS01440 3d5b2634b27071c0123938f3095e7cee 242 PANTHER PTHR24260:SF50 16 240 3.0E-135 T 16-09-2016 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 SUPERFAMILY SSF103473 25 454 3.27E-71 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 PANTHER PTHR23511 27 455 1.5E-131 T 16-09-2016 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 16-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 PRINTS PR00171 Sugar transporter signature 386 398 5.3E-7 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 PRINTS PR00171 Sugar transporter signature 129 148 5.3E-7 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 PRINTS PR00171 Sugar transporter signature 46 56 5.3E-7 T 16-09-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 Pfam PF00083 Sugar (and other) transporter 71 454 1.9E-50 T 16-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 PANTHER PTHR23511:SF10 27 455 1.5E-131 T 16-09-2016 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 Gene3D G3DSA:1.20.1250.20 41 219 1.5E-27 T 16-09-2016 Spa2297_RS00500 26d8f40a0b32fc35ccdfb81de52aa590 456 Gene3D G3DSA:1.20.1250.20 271 451 1.5E-16 T 16-09-2016 Spa2297_RS22125 30fd89ad38d99a6fe0a10fc025f17fc3 536 Pfam PF00474 Sodium:solute symporter family 44 406 1.1E-18 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS22125 30fd89ad38d99a6fe0a10fc025f17fc3 536 PANTHER PTHR11819:SF2 6 529 2.5E-228 T 16-09-2016 Spa2297_RS22125 30fd89ad38d99a6fe0a10fc025f17fc3 536 PANTHER PTHR11819 6 529 2.5E-228 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 SUPERFAMILY SSF52540 252 499 5.1E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 PANTHER PTHR24220 7 395 3.5E-213 T 16-09-2016 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 PANTHER PTHR24220:SF392 7 395 3.5E-213 T 16-09-2016 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 Gene3D G3DSA:3.40.50.300 3 228 9.4E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 SMART SM00382 30 220 1.0E-9 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 SMART SM00382 293 496 0.0022 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 Gene3D G3DSA:3.40.50.300 258 505 1.7E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 Pfam PF00005 ABC transporter 285 440 5.4E-17 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 Pfam PF00005 ABC transporter 21 172 2.4E-27 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS10125 9f50f432ee58b0fcdc7f03781c35dc02 519 SUPERFAMILY SSF52540 4 228 1.28E-54 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29055 0a7da3e7eac9c94ab4c9afb4f564e211 163 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 6 109 1.6E-6 T 16-09-2016 IPR005519 Acid phosphatase, class B-like Spa2297_RS29055 0a7da3e7eac9c94ab4c9afb4f564e211 163 SUPERFAMILY SSF56784 5 146 4.56E-20 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS29055 0a7da3e7eac9c94ab4c9afb4f564e211 163 Gene3D G3DSA:3.40.50.1000 8 141 1.2E-16 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS04525 6e044254f8e21c8932723995ebf43ed7 76 Pfam PF04149 Domain of unknown function (DUF397) 18 74 5.2E-20 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS12540 c046d6c067009db86bda15965ff62bb5 215 SUPERFAMILY SSF161098 13 198 1.83E-29 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12540 c046d6c067009db86bda15965ff62bb5 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 206 5.0E-19 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12540 c046d6c067009db86bda15965ff62bb5 215 Gene3D G3DSA:1.10.3720.10 12 203 1.9E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS12540 c046d6c067009db86bda15965ff62bb5 215 PANTHER PTHR30177 1 214 5.9E-171 T 16-09-2016 Spa2297_RS12540 c046d6c067009db86bda15965ff62bb5 215 PANTHER PTHR30177:SF13 1 214 5.9E-171 T 16-09-2016 Spa2297_RS32590 5bc0eef07640e5dea7390e96abe666d2 273 Pfam PF01032 FecCD transport family 71 271 9.0E-46 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS32590 5bc0eef07640e5dea7390e96abe666d2 273 PANTHER PTHR30472 53 273 9.6E-84 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS32590 5bc0eef07640e5dea7390e96abe666d2 273 Gene3D G3DSA:1.10.3470.10 64 272 9.5E-54 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS32590 5bc0eef07640e5dea7390e96abe666d2 273 PANTHER PTHR30472:SF32 53 273 9.6E-84 T 16-09-2016 Spa2297_RS32590 5bc0eef07640e5dea7390e96abe666d2 273 SUPERFAMILY SSF81345 62 269 1.7E-38 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS17600 a11583fe8755657f73efc67895c3bf3c 271 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 9 271 37.123 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS17600 a11583fe8755657f73efc67895c3bf3c 271 PANTHER PTHR10138 1 271 2.4E-83 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS17600 a11583fe8755657f73efc67895c3bf3c 271 PANTHER PTHR10138:SF0 1 271 2.4E-83 T 16-09-2016 Spa2297_RS17600 a11583fe8755657f73efc67895c3bf3c 271 SUPERFAMILY SSF140959 15 270 4.05E-79 T 16-09-2016 Spa2297_RS17600 a11583fe8755657f73efc67895c3bf3c 271 Pfam PF03301 Tryptophan 2,3-dioxygenase 1 271 1.2E-87 T 16-09-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 65 4.5E-11 T 16-09-2016 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 PANTHER PTHR10668 6 72 4.0E-14 T 16-09-2016 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 256 4.7E-5 T 16-09-2016 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.7E-5 T 16-09-2016 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 SUPERFAMILY SSF51905 310 378 1.94E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 SUPERFAMILY SSF51905 1 225 1.94E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 Gene3D G3DSA:3.40.50.720 4 75 1.1E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 Gene3D G3DSA:3.40.50.720 164 226 1.1E-20 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 347 354 9.5E-6 T 16-09-2016 Spa2297_RS14930 6580ceb1d20ce0c880841a89dd3c3b54 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.5E-6 T 16-09-2016 Spa2297_RS05100 5bc7b9b58cc5fc9a88d835ed1ff2294b 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS05100 5bc7b9b58cc5fc9a88d835ed1ff2294b 202 PANTHER PTHR14269 5 189 7.7E-33 T 16-09-2016 Spa2297_RS05100 5bc7b9b58cc5fc9a88d835ed1ff2294b 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 8.4E-15 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS05100 5bc7b9b58cc5fc9a88d835ed1ff2294b 202 PIRSF PIRSF000847 11 202 2.7E-43 T 16-09-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 Gene3D G3DSA:3.90.420.10 74 294 2.1E-67 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 SUPERFAMILY SSF81296 326 417 7.7E-24 T 16-09-2016 IPR014756 Immunoglobulin E-set Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PANTHER PTHR19372 77 413 7.3E-71 T 16-09-2016 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 SUPERFAMILY SSF56524 71 294 1.96E-58 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 327 410 2.7E-9 T 16-09-2016 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 Gene3D G3DSA:2.60.40.650 317 417 5.9E-23 T 16-09-2016 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 Pfam PF00174 Oxidoreductase molybdopterin binding domain 102 283 1.3E-49 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 246 259 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 341 353 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 229 245 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 173 188 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 386 398 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 262 275 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS31180 65d3b1c633e5bfa9570335f069fe65ff 419 PRINTS PR00407 Eukaryotic molybdopterin domain signature 90 106 3.1E-25 T 16-09-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 3.0E-34 T 16-09-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 21.971 T 16-09-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 SUPERFAMILY SSF82697 3 81 3.14E-25 T 16-09-2016 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 Gene3D G3DSA:3.30.1280.10 3 81 1.1E-32 T 16-09-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 8.4E-28 T 16-09-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 80 2.3E-20 T 16-09-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 Spa2297_RS15800 1e97f279a2111a280bb163443c1d92c5 90 PANTHER PTHR34696 1 85 8.5E-34 T 16-09-2016 Spa2297_RS16115 a776a637159e5958d0a4c9dff3ce7270 291 SMART SM00943 16 200 2.6E-42 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS16115 a776a637159e5958d0a4c9dff3ce7270 291 SUPERFAMILY SSF56747 13 210 3.33E-36 T 16-09-2016 Spa2297_RS16115 a776a637159e5958d0a4c9dff3ce7270 291 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 16 197 1.1E-42 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS16115 a776a637159e5958d0a4c9dff3ce7270 291 SMART SM00942 227 289 4.0E-9 T 16-09-2016 IPR014820 Primase, C-terminal 1 Spa2297_RS02880 f33070feedcfe72568c249ed6d98ca06 354 Pfam PF13649 Methyltransferase domain 176 271 1.6E-15 T 16-09-2016 Spa2297_RS02880 f33070feedcfe72568c249ed6d98ca06 354 SUPERFAMILY SSF53335 163 339 4.84E-27 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02880 f33070feedcfe72568c249ed6d98ca06 354 Gene3D G3DSA:3.40.50.150 173 342 4.6E-27 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS02880 f33070feedcfe72568c249ed6d98ca06 354 PANTHER PTHR10108 175 270 8.3E-15 T 16-09-2016 Spa2297_RS23950 e04a621ce0733071a0e23625b047b233 369 Pfam PF08933 Domain of unknown function (DUF1864) 61 352 9.3E-38 T 16-09-2016 IPR015029 Protein of unknown function DUF1864 KEGG: 00053+4.1.1.-|KEGG: 00230+4.1.1.-|KEGG: 00261+4.1.1.-|KEGG: 00350+4.1.1.-|KEGG: 00351+4.1.1.-|KEGG: 00360+4.1.1.-|KEGG: 00362+4.1.1.-|KEGG: 00380+4.1.1.-|KEGG: 00620+4.1.1.-|KEGG: 00621+4.1.1.-|KEGG: 00622+4.1.1.-|KEGG: 00624+4.1.1.-|KEGG: 00625+4.1.1.-|KEGG: 00626+4.1.1.-|KEGG: 00940+4.1.1.-|UniPathway: UPA00628 Spa2297_RS23950 e04a621ce0733071a0e23625b047b233 369 SUPERFAMILY SSF140959 59 351 6.08E-23 T 16-09-2016 Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 SUPERFAMILY SSF53448 10 291 5.84E-64 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 9.1E-104 T 16-09-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 PANTHER PTHR22572 10 293 7.8E-100 T 16-09-2016 Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 Pfam PF00483 Nucleotidyl transferase 10 274 4.4E-27 T 16-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 Gene3D G3DSA:3.90.550.10 10 282 3.7E-75 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS13855 b93a39d65e008af019bf1529dd2069c3 300 PANTHER PTHR22572:SF14 10 293 7.8E-100 T 16-09-2016 Spa2297_RS25580 783563038bc0847fe1284b2e6579bcba 119 PANTHER PTHR36221 5 119 6.2E-39 T 16-09-2016 Spa2297_RS25580 783563038bc0847fe1284b2e6579bcba 119 SUPERFAMILY SSF46785 42 96 8.85E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25580 783563038bc0847fe1284b2e6579bcba 119 Gene3D G3DSA:1.10.10.10 52 93 4.6E-4 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25580 783563038bc0847fe1284b2e6579bcba 119 Pfam PF05331 Protein of unknown function (DUF742) 8 119 2.1E-38 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 33 193 3.0E-14 T 16-09-2016 IPR005137 Photosystem I BtpA, assembly Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 Gene3D G3DSA:3.20.20.70 40 244 1.2E-7 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 SUPERFAMILY SSF51366 16 262 1.41E-9 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 11 264 3.7E-46 T 16-09-2016 IPR005137 Photosystem I BtpA, assembly Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 Pfam PF03437 BtpA family 10 264 7.2E-44 T 16-09-2016 IPR005137 Photosystem I BtpA, assembly Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 PIRSF PIRSF005956 1 269 2.9E-70 T 16-09-2016 IPR005137 Photosystem I BtpA, assembly Spa2297_RS02975 51bfa6b0740fd4ffda8a65d60e86d665 269 PANTHER PTHR21381 1 269 3.8E-48 T 16-09-2016 IPR005137 Photosystem I BtpA, assembly Spa2297_RS27040 ccbdf1be628ddf09862bb7bd1a373eb7 169 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 16 95 1.8E-7 T 16-09-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 SUPERFAMILY SSF53335 9 237 2.56E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 PANTHER PTHR10108:SF705 19 169 9.8E-28 T 16-09-2016 Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 PANTHER PTHR10108:SF705 187 213 9.8E-28 T 16-09-2016 Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 Gene3D G3DSA:3.40.50.150 19 213 5.2E-35 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 PANTHER PTHR10108 187 213 9.8E-28 T 16-09-2016 Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 Pfam PF13649 Methyltransferase domain 60 153 1.3E-22 T 16-09-2016 Spa2297_RS03100 2a5b044e882f69f7d179aca2d3827ab7 241 PANTHER PTHR10108 19 169 9.8E-28 T 16-09-2016 Spa2297_RS26790 5196af19782e017164dd50dcafb15590 354 Gene3D G3DSA:3.90.1550.10 90 350 4.9E-68 T 16-09-2016 Spa2297_RS26790 5196af19782e017164dd50dcafb15590 354 Pfam PF03099 Biotin/lipoate A/B protein ligase family 159 266 6.5E-6 T 16-09-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 Spa2297_RS26790 5196af19782e017164dd50dcafb15590 354 SUPERFAMILY SSF55681 96 350 1.92E-67 T 16-09-2016 Spa2297_RS26790 5196af19782e017164dd50dcafb15590 354 PANTHER PTHR12561 66 350 2.4E-104 T 16-09-2016 Spa2297_RS26790 5196af19782e017164dd50dcafb15590 354 PANTHER PTHR12561:SF7 66 350 2.4E-104 T 16-09-2016 Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 PANTHER PTHR30055 4 159 1.1E-52 T 16-09-2016 Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 PANTHER PTHR30055:SF78 4 159 1.1E-52 T 16-09-2016 Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 SUPERFAMILY SSF48498 88 212 8.67E-32 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 SUPERFAMILY SSF46689 9 83 8.03E-18 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 7.5E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS14720 4615eb2b9f225e53d85c1357893478a5 215 Gene3D G3DSA:1.10.357.10 1 196 2.0E-47 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS00895 9341d1162c7d259365581509ff1d43f1 441 PANTHER PTHR31310:SF7 11 362 1.9E-81 T 16-09-2016 Spa2297_RS00895 9341d1162c7d259365581509ff1d43f1 441 Pfam PF14378 PAP2 superfamily 165 349 9.6E-20 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS00895 9341d1162c7d259365581509ff1d43f1 441 PANTHER PTHR31310 11 362 1.9E-81 T 16-09-2016 Spa2297_RS08460 0e62700d9fb1923d536ad628ef4e18c0 528 PANTHER PTHR10110:SF86 4 498 2.1E-109 T 16-09-2016 Spa2297_RS08460 0e62700d9fb1923d536ad628ef4e18c0 528 PANTHER PTHR10110 4 498 2.1E-109 T 16-09-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 Spa2297_RS08460 0e62700d9fb1923d536ad628ef4e18c0 528 Pfam PF00999 Sodium/hydrogen exchanger family 9 404 5.5E-58 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS08460 0e62700d9fb1923d536ad628ef4e18c0 528 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 15 525 2.9E-98 T 16-09-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 Spa2297_RS15225 431b3eba6a0b80ea15ff5551548a66d7 370 Gene3D G3DSA:3.90.1200.10 177 282 8.3E-16 T 16-09-2016 Spa2297_RS15225 431b3eba6a0b80ea15ff5551548a66d7 370 Pfam PF01636 Phosphotransferase enzyme family 28 256 8.6E-20 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS15225 431b3eba6a0b80ea15ff5551548a66d7 370 SUPERFAMILY SSF56112 46 261 1.96E-19 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS15355 87faaecc076520f335b6d58f93f94042 91 Pfam PF11298 Protein of unknown function (DUF3099) 3 60 1.6E-6 T 16-09-2016 IPR021449 Protein of unknown function DUF3099 Spa2297_RS21400 20abb2ea4a69a2d42c25bb18c9e63d20 70 Pfam PF14117 Domain of unknown function (DUF4287) 7 63 1.6E-29 T 16-09-2016 IPR025629 Protein of unknown function DUF4287 Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 Gene3D G3DSA:3.20.20.100 2 324 1.4E-105 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 Pfam PF00248 Aldo/keto reductase family 16 324 1.6E-57 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 PANTHER PTHR11732:SF12 170 324 5.9E-112 T 16-09-2016 Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 PANTHER PTHR11732:SF12 1 154 5.9E-112 T 16-09-2016 Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 PANTHER PTHR11732 170 324 5.9E-112 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 PANTHER PTHR11732 1 154 5.9E-112 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS23315 cd649fc9aa8125e81a59f554c15e709d 332 SUPERFAMILY SSF51430 2 324 6.94E-84 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS12830 67a234a1393e8db3a970345ee283a33c 305 PIRSF PIRSF003097 1 305 6.3E-77 T 16-09-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 Spa2297_RS12830 67a234a1393e8db3a970345ee283a33c 305 Pfam PF02687 FtsX-like permease family 184 304 2.9E-12 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS12830 67a234a1393e8db3a970345ee283a33c 305 PANTHER PTHR30489 49 305 4.1E-36 T 16-09-2016 Spa2297_RS09685 4be09fedd4fdb08e1e6a6588f4a6e7d6 362 SUPERFAMILY SSF48208 43 340 3.74E-39 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS09685 4be09fedd4fdb08e1e6a6588f4a6e7d6 362 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 137 153 2.1 T 16-09-2016 IPR001330 PFTB repeat GO:0003824 Spa2297_RS09685 4be09fedd4fdb08e1e6a6588f4a6e7d6 362 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 75 90 0.0039 T 16-09-2016 IPR001330 PFTB repeat GO:0003824 Spa2297_RS09685 4be09fedd4fdb08e1e6a6588f4a6e7d6 362 Gene3D G3DSA:1.50.10.20 27 210 5.8E-16 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 Gene3D G3DSA:3.30.43.10 4 112 2.6E-18 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 Pfam PF01565 FAD binding domain 56 195 1.0E-34 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 Pfam PF02913 FAD linked oxidases, C-terminal domain 233 480 2.0E-24 T 16-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 SUPERFAMILY SSF55103 242 484 5.23E-28 T 16-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 PANTHER PTHR11748:SF3 11 485 9.6E-117 T 16-09-2016 IPR025650 Alkyldihydroxyacetonephosphate synthase GO:0008609|GO:0008610 KEGG: 00565+2.5.1.26|UniPathway: UPA00781 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 SUPERFAMILY SSF56176 6 230 6.54E-49 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 Gene3D G3DSA:3.30.465.10 113 230 2.8E-29 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 PANTHER PTHR11748 11 485 9.6E-117 T 16-09-2016 Spa2297_RS31555 e3af638e816d3d92ce3648adcbc61cba 487 Gene3D G3DSA:1.10.45.10 444 480 8.8E-5 T 16-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Spa2297_RS02605 e8f21f1319419ddb5e66a395182a3340 353 SUPERFAMILY SSF52242 95 210 8.32E-18 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS02605 e8f21f1319419ddb5e66a395182a3340 353 Gene3D G3DSA:3.40.50.280 95 207 2.2E-18 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS02605 e8f21f1319419ddb5e66a395182a3340 353 Pfam PF02607 B12 binding domain 12 85 1.9E-10 T 16-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spa2297_RS02605 e8f21f1319419ddb5e66a395182a3340 353 Pfam PF02310 B12 binding domain 96 209 8.3E-17 T 16-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Spa2297_RS24065 6cde2143e09722eb1cb62879e7c978d6 543 Pfam PF07905 Purine catabolism regulatory protein-like family 9 126 1.3E-32 T 16-09-2016 IPR012914 Purine catabolism PurC-like domain Spa2297_RS24065 6cde2143e09722eb1cb62879e7c978d6 543 PANTHER PTHR33744 2 540 5.7E-166 T 16-09-2016 Spa2297_RS24065 6cde2143e09722eb1cb62879e7c978d6 543 Pfam PF13556 PucR C-terminal helix-turn-helix domain 481 539 8.3E-23 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS24065 6cde2143e09722eb1cb62879e7c978d6 543 PANTHER PTHR33744:SF3 2 540 5.7E-166 T 16-09-2016 Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 2.8E-11 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 PANTHER PTHR24567:SF32 1 134 1.5E-23 T 16-09-2016 Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 Gene3D G3DSA:2.60.120.10 4 135 7.4E-18 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 SMART SM00100 7 128 1.2E-7 T 16-09-2016 IPR000595 Cyclic nucleotide-binding domain Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 PANTHER PTHR24567 1 134 1.5E-23 T 16-09-2016 Spa2297_RS02130 ea7cbddd057ae8792ff5fb110683d0d9 151 SUPERFAMILY SSF51206 3 132 1.22E-21 T 16-09-2016 IPR018490 Cyclic nucleotide-binding-like Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 SUPERFAMILY SSF52540 4 234 8.45E-43 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 PANTHER PTHR24220 5 245 4.0E-126 T 16-09-2016 Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 PANTHER PTHR24220:SF85 5 245 4.0E-126 T 16-09-2016 Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 Gene3D G3DSA:3.40.50.300 3 235 1.7E-47 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 Pfam PF00005 ABC transporter 23 174 7.5E-22 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 SMART SM00382 32 226 2.2E-5 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS07740 49423830fb618132ee9b5e846807f4ff 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.0E-104 T 16-09-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 PANTHER PTHR35010:SF1 1 291 1.0E-155 T 16-09-2016 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 Pfam PF13560 Helix-turn-helix domain 11 90 2.4E-15 T 16-09-2016 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 SUPERFAMILY SSF47413 35 86 1.85E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 PANTHER PTHR35010 1 291 1.0E-155 T 16-09-2016 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 SMART SM00530 15 87 3.3E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS19740 ef67799b0e4231aa20750355690c9553 305 Gene3D G3DSA:1.10.260.40 10 86 3.5E-17 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS19045 84cac8f1c2bb43c338940e62ef9e8c8a 306 Gene3D G3DSA:1.20.1250.20 103 160 1.0E-4 T 16-09-2016 Spa2297_RS19045 84cac8f1c2bb43c338940e62ef9e8c8a 306 Pfam PF00482 Type II secretion system (T2SS), protein F 171 297 1.1E-9 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 Gene3D G3DSA:3.40.1190.10 47 284 6.3E-36 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 4.9E-22 T 16-09-2016 IPR013564 Domain of unknown function DUF1727 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 PANTHER PTHR23135 40 412 5.2E-155 T 16-09-2016 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 PANTHER PTHR23135:SF7 40 412 5.2E-155 T 16-09-2016 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 Pfam PF08245 Mur ligase middle domain 65 265 1.1E-11 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 SUPERFAMILY SSF53623 50 196 9.68E-28 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS04380 3c79ff086d2e8b1a17201a6e94655941 412 SUPERFAMILY SSF53623 226 279 9.68E-28 T 16-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 SUPERFAMILY SSF50331 66 129 8.02E-17 T 16-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 66 128 3.4E-16 T 16-09-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 49 3.8E-9 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 PANTHER PTHR30432 1 130 1.0E-28 T 16-09-2016 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 Gene3D G3DSA:1.10.1660.10 4 48 1.8E-7 T 16-09-2016 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 Gene3D G3DSA:2.40.50.100 66 128 4.5E-22 T 16-09-2016 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 Pfam PF12728 Helix-turn-helix domain 4 49 9.8E-11 T 16-09-2016 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 Pfam PF03459 TOBE domain 66 128 3.3E-17 T 16-09-2016 IPR005116 Transport-associated OB, type 1 Spa2297_RS17250 5f971038a4edd3096ecce64951da3370 131 SUPERFAMILY SSF46955 4 53 2.11E-10 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS19500 b9473164a964b0deaeeaf4e8c13e486f 138 PIRSF PIRSF028777 1 130 2.6E-51 T 16-09-2016 IPR031308 Uncharacterised conserved protein UCP028777 Spa2297_RS19500 b9473164a964b0deaeeaf4e8c13e486f 138 PANTHER PTHR31503 3 121 2.7E-42 T 16-09-2016 Spa2297_RS19500 b9473164a964b0deaeeaf4e8c13e486f 138 Pfam PF03733 Inner membrane component domain 4 53 1.8E-17 T 16-09-2016 IPR005185 Inner membrane component domain Spa2297_RS19500 b9473164a964b0deaeeaf4e8c13e486f 138 Pfam PF03733 Inner membrane component domain 68 118 1.6E-17 T 16-09-2016 IPR005185 Inner membrane component domain Spa2297_RS21060 5bffa9d74073e654ff29f801f58f6bb9 244 Pfam PF01927 Mut7-C RNAse domain 90 231 5.8E-41 T 16-09-2016 IPR002782 Mut7-C RNAse domain Spa2297_RS21060 5bffa9d74073e654ff29f801f58f6bb9 244 PANTHER PTHR12124 71 238 6.2E-15 T 16-09-2016 Spa2297_RS21060 5bffa9d74073e654ff29f801f58f6bb9 244 PANTHER PTHR12124:SF44 71 238 6.2E-15 T 16-09-2016 Spa2297_RS21060 5bffa9d74073e654ff29f801f58f6bb9 244 Pfam PF14451 Mut7-C ubiquitin 4 82 2.9E-23 T 16-09-2016 IPR027798 Ubiquitin Mut7-C domain Spa2297_RS27555 11190c2168b8c11273a1db4a7a293025 272 Gene3D G3DSA:3.40.50.150 9 270 6.6E-109 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27555 11190c2168b8c11273a1db4a7a293025 272 PIRSF PIRSF017393 1 271 2.4E-112 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS27555 11190c2168b8c11273a1db4a7a293025 272 SUPERFAMILY SSF53335 21 256 5.26E-41 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27555 11190c2168b8c11273a1db4a7a293025 272 Pfam PF04672 S-adenosyl methyltransferase 11 270 1.1E-109 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS11495 6de13186edc5a3c6675ed5eb4331093d 253 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 218 248 8.9E-5 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS11495 6de13186edc5a3c6675ed5eb4331093d 253 Pfam PF03777 Small secreted domain (DUF320) 99 153 1.4E-24 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS11495 6de13186edc5a3c6675ed5eb4331093d 253 Pfam PF03777 Small secreted domain (DUF320) 16 71 5.5E-26 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS21040 4bb3ba40105b1cd661379d1cdeb0406b 133 Pfam PF14267 Domain of unknown function (DUF4357) 90 123 1.5E-9 T 16-09-2016 IPR025579 Domain of unknown function DUF4357 Spa2297_RS01355 66f4d0eaa74a8316aedf66c5d2635166 405 Pfam PF05426 Alginate lyase 114 335 5.5E-10 T 16-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Spa2297_RS01355 66f4d0eaa74a8316aedf66c5d2635166 405 Gene3D G3DSA:1.50.10.110 91 387 4.2E-35 T 16-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Spa2297_RS01355 66f4d0eaa74a8316aedf66c5d2635166 405 SUPERFAMILY SSF48230 286 348 8.51E-45 T 16-09-2016 IPR008929 Chondroitin AC/alginate lyase Spa2297_RS01355 66f4d0eaa74a8316aedf66c5d2635166 405 SUPERFAMILY SSF48230 46 256 8.51E-45 T 16-09-2016 IPR008929 Chondroitin AC/alginate lyase Spa2297_RS18445 fae3c8fc60d158138c43368cda4d490d 281 Pfam PF01261 Xylose isomerase-like TIM barrel 31 218 7.2E-19 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS18445 fae3c8fc60d158138c43368cda4d490d 281 PANTHER PTHR12110 8 270 2.6E-76 T 16-09-2016 Spa2297_RS18445 fae3c8fc60d158138c43368cda4d490d 281 Gene3D G3DSA:3.20.20.150 10 267 1.3E-48 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS18445 fae3c8fc60d158138c43368cda4d490d 281 SUPERFAMILY SSF51658 8 270 7.07E-48 T 16-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain Spa2297_RS18445 fae3c8fc60d158138c43368cda4d490d 281 PANTHER PTHR12110:SF17 8 270 2.6E-76 T 16-09-2016 Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 SUPERFAMILY SSF54631 1 144 3.77E-33 T 16-09-2016 Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 PANTHER PTHR11911 86 144 2.6E-30 T 16-09-2016 Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 PANTHER PTHR11911 5 64 2.6E-30 T 16-09-2016 Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 PIRSF PIRSF036990 4 219 1.4E-50 T 16-09-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 SMART SM00116 13 61 6.3E-4 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 SMART SM00116 95 143 1.6E-11 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 Pfam PF04972 BON domain 146 211 4.4E-11 T 16-09-2016 IPR007055 BON domain Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 Pfam PF00571 CBS domain 6 61 1.0E-9 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 Pfam PF00571 CBS domain 89 142 1.3E-15 T 16-09-2016 IPR000644 CBS domain Spa2297_RS03990 13aa6f73854d07cc1239a4757185746e 223 Gene3D G3DSA:3.10.580.10 5 143 3.0E-31 T 16-09-2016 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 Pfam PF02277 Phosphoribosyltransferase 13 344 3.2E-98 T 16-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 Gene3D G3DSA:3.40.50.10210 73 335 8.9E-85 T 16-09-2016 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 344 2.4E-101 T 16-09-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 Gene3D G3DSA:1.10.1610.10 6 72 2.1E-15 T 16-09-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 PANTHER PTHR21712 13 340 4.8E-194 T 16-09-2016 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 SUPERFAMILY SSF52733 7 344 2.88E-85 T 16-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 Spa2297_RS08985 300fee6d15caef296a0b32b07d9f616f 357 PANTHER PTHR21712:SF33 13 340 4.8E-194 T 16-09-2016 Spa2297_RS11630 ff2fec2b58a18f61cf6ed878e714e0ff 386 Gene3D G3DSA:3.20.20.70 55 331 7.9E-9 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS11630 ff2fec2b58a18f61cf6ed878e714e0ff 386 Pfam PF06187 Protein of unknown function (DUF993) 3 384 4.2E-185 T 16-09-2016 IPR009334 Protein of unknown function DUF993 Spa2297_RS11630 ff2fec2b58a18f61cf6ed878e714e0ff 386 SUPERFAMILY SSF51569 53 333 8.16E-16 T 16-09-2016 Spa2297_RS25935 380d200518f0edd5f59662158bdfcb60 157 Pfam PF00072 Response regulator receiver domain 16 128 1.5E-17 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS25935 380d200518f0edd5f59662158bdfcb60 157 Gene3D G3DSA:3.40.50.2300 12 138 1.2E-26 T 16-09-2016 Spa2297_RS25935 380d200518f0edd5f59662158bdfcb60 157 PANTHER PTHR26402 14 135 5.2E-21 T 16-09-2016 Spa2297_RS25935 380d200518f0edd5f59662158bdfcb60 157 SUPERFAMILY SSF52172 13 138 3.7E-25 T 16-09-2016 IPR011006 CheY-like superfamily Spa2297_RS25935 380d200518f0edd5f59662158bdfcb60 157 SMART SM00448 14 131 1.7E-18 T 16-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 PANTHER PTHR13794 1 419 2.4E-193 T 16-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 Pfam PF13378 Enolase C-terminal domain-like 182 391 5.5E-48 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 141 5.2E-8 T 16-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 SMART SM00922 178 272 2.9E-17 T 16-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 Gene3D G3DSA:3.30.390.10 3 143 1.8E-36 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 PANTHER PTHR13794:SF56 1 419 2.4E-193 T 16-09-2016 Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 SUPERFAMILY SSF54826 5 141 3.37E-24 T 16-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 SUPERFAMILY SSF51604 141 396 4.24E-67 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS10710 8e3a5524bf9c407d1b69450d2889ac2a 431 Gene3D G3DSA:3.20.20.120 144 385 8.2E-71 T 16-09-2016 IPR029065 Enolase C-terminal domain-like Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.839 T 16-09-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.7E-29 T 16-09-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 3.5E-38 T 16-09-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 SMART SM00316 5 73 3.8E-5 T 16-09-2016 IPR022967 RNA-binding domain, S1 Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 PANTHER PTHR33370 1 73 4.0E-47 T 16-09-2016 Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 SUPERFAMILY SSF50249 4 72 9.3E-28 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS19910 ffd3dec81afb81d0a38d164adb6bf337 73 Gene3D G3DSA:2.40.50.140 2 73 1.5E-39 T 16-09-2016 IPR012340 Nucleic acid-binding, OB-fold Spa2297_RS05680 9e2df98227465b9f0ac1876f3691f584 146 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 7.2E-11 T 16-09-2016 IPR009293 Uncharacterised protein family UPF0478 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 Gene3D G3DSA:3.90.1150.10 413 516 2.4E-4 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 PANTHER PTHR11751 450 513 8.7E-33 T 16-09-2016 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 PANTHER PTHR11751 143 425 8.7E-33 T 16-09-2016 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 Gene3D G3DSA:3.40.640.10 154 378 1.2E-37 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 Pfam PF00155 Aminotransferase class I and II 133 513 1.1E-23 T 16-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 SUPERFAMILY SSF53383 418 515 1.04E-47 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS02970 70e263817e5284d5ddd12e15683ad906 522 SUPERFAMILY SSF53383 133 383 1.04E-47 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS06240 05dfc91506444a3772d7ef364cd351ff 384 PANTHER PTHR31686 15 384 5.7E-254 T 16-09-2016 Spa2297_RS06240 05dfc91506444a3772d7ef364cd351ff 384 PANTHER PTHR31686:SF2 15 384 5.7E-254 T 16-09-2016 Spa2297_RS06240 05dfc91506444a3772d7ef364cd351ff 384 Pfam PF03595 Voltage-dependent anion channel 22 357 1.0E-62 T 16-09-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PANTHER PTHR30294:SF14 12 307 1.1E-73 T 16-09-2016 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PANTHER PTHR30294 12 307 1.1E-73 T 16-09-2016 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PRINTS PR00164 ABC-2 type transport system membrane protein signature 180 204 1.4E-5 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PRINTS PR00164 ABC-2 type transport system membrane protein signature 104 126 1.4E-5 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PRINTS PR00164 ABC-2 type transport system membrane protein signature 217 236 1.4E-5 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 PRINTS PR00164 ABC-2 type transport system membrane protein signature 73 94 1.4E-5 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS12930 91f9b61e9fb40010a3f62def290def2a 308 Pfam PF01061 ABC-2 type transporter 62 266 4.9E-17 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS29185 a459e754def1e4ed5a16d87a451b4bd8 473 Pfam PF03929 PepSY-associated TM region 33 399 2.6E-55 T 16-09-2016 IPR005625 PepSY-associated TM protein Spa2297_RS29185 a459e754def1e4ed5a16d87a451b4bd8 473 PANTHER PTHR34219:SF1 24 460 1.0E-114 T 16-09-2016 Spa2297_RS29185 a459e754def1e4ed5a16d87a451b4bd8 473 PANTHER PTHR34219 24 460 1.0E-114 T 16-09-2016 Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 PANTHER PTHR22762 146 751 1.3E-194 T 16-09-2016 Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 Pfam PF01055 Glycosyl hydrolases family 31 269 709 1.9E-112 T 16-09-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 SUPERFAMILY SSF51011 625 704 8.63E-20 T 16-09-2016 Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 SUPERFAMILY SSF51445 280 623 6.74E-71 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 SUPERFAMILY SSF74650 88 238 7.22E-8 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS05140 f1ba9af753199deae4f92a98b1f0eeff 789 PANTHER PTHR22762:SF7 146 751 1.3E-194 T 16-09-2016 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 SUPERFAMILY SSF55486 42 167 9.11E-20 T 16-09-2016 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 43 168 4.7E-30 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 50 167 1.0E-54 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 Gene3D G3DSA:3.40.390.10 43 172 2.8E-26 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 132 156 3.5E-21 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 159 173 3.5E-21 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 48 74 3.5E-21 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS31695 a73f8c36b798dc51511ba4fbd94c50b7 187 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 107 131 3.5E-21 T 16-09-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 Spa2297_RS04150 a34cb586491240e15347c8eca9ce3c6d 137 PANTHER PTHR36221 1 137 1.4E-38 T 16-09-2016 Spa2297_RS04150 a34cb586491240e15347c8eca9ce3c6d 137 Pfam PF05331 Protein of unknown function (DUF742) 21 137 7.7E-39 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 SUPERFAMILY SSF53901 267 387 5.32E-43 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 PIRSF PIRSF000429 1 389 2.4E-120 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Gene3D G3DSA:3.40.47.10 189 271 6.1E-66 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Gene3D G3DSA:3.40.47.10 4 126 6.1E-66 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Pfam PF00108 Thiolase, N-terminal domain 5 258 5.8E-63 T 16-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 PANTHER PTHR18919 1 389 8.8E-222 T 16-09-2016 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Pfam PF02803 Thiolase, C-terminal domain 267 387 4.1E-45 T 16-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 SUPERFAMILY SSF53901 1 263 6.51E-71 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Gene3D G3DSA:3.40.47.10 151 188 3.7E-58 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 Gene3D G3DSA:3.40.47.10 273 387 3.7E-58 T 16-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 16-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 387 2.7E-142 T 16-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 Spa2297_RS04865 b27f665d8994493d219b04e335483f98 389 PANTHER PTHR18919:SF71 1 389 8.8E-222 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737 313 407 1.2E-108 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737 3 90 1.2E-108 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 42.125 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 3.0E-48 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737:SF13 313 407 1.2E-108 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737:SF13 3 90 1.2E-108 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737:SF13 151 291 1.2E-108 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 Gene3D G3DSA:3.75.10.10 2 66 1.7E-126 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 Gene3D G3DSA:3.75.10.10 151 407 1.7E-126 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PANTHER PTHR12737 151 291 1.2E-108 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 PIRSF PIRSF006356 1 407 1.6E-151 T 16-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 SUPERFAMILY SSF55909 2 407 1.45E-125 T 16-09-2016 Spa2297_RS25110 27ef9feebf1e87463ed03bbd9d38d529 407 Pfam PF02274 Amidinotransferase 17 404 1.4E-88 T 16-09-2016 Spa2297_RS11350 dc48d1c0c285eb18ee3724a525b0c85f 136 PANTHER PTHR31793 2 133 3.0E-32 T 16-09-2016 Spa2297_RS11350 dc48d1c0c285eb18ee3724a525b0c85f 136 Gene3D G3DSA:3.10.129.10 2 128 1.1E-43 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS11350 dc48d1c0c285eb18ee3724a525b0c85f 136 Pfam PF03061 Thioesterase superfamily 17 94 2.3E-15 T 16-09-2016 IPR006683 Thioesterase domain Spa2297_RS11350 dc48d1c0c285eb18ee3724a525b0c85f 136 PANTHER PTHR31793:SF1 2 133 3.0E-32 T 16-09-2016 Spa2297_RS11350 dc48d1c0c285eb18ee3724a525b0c85f 136 SUPERFAMILY SSF54637 2 126 4.64E-32 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS13210 754fac2469ce7eb6c5f4e9ca43f81243 397 PANTHER PTHR33392:SF6 15 395 3.1E-119 T 16-09-2016 Spa2297_RS13210 754fac2469ce7eb6c5f4e9ca43f81243 397 PANTHER PTHR33392 15 395 3.1E-119 T 16-09-2016 Spa2297_RS13210 754fac2469ce7eb6c5f4e9ca43f81243 397 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 154 309 4.5E-45 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13210 754fac2469ce7eb6c5f4e9ca43f81243 397 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 154 309 3.5E-41 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS23460 52925f2860ca0acdb0476a847e5d72e5 190 PANTHER PTHR36221 57 190 5.4E-42 T 16-09-2016 Spa2297_RS23460 52925f2860ca0acdb0476a847e5d72e5 190 Pfam PF05331 Protein of unknown function (DUF742) 78 190 8.7E-42 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS23840 9fafa612cbdf9500be0a0d57613a8a03 375 PANTHER PTHR13773:SF0 2 372 4.8E-205 T 16-09-2016 Spa2297_RS23840 9fafa612cbdf9500be0a0d57613a8a03 375 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 329 355 - T 16-09-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 Spa2297_RS23840 9fafa612cbdf9500be0a0d57613a8a03 375 PANTHER PTHR13773 2 372 4.8E-205 T 16-09-2016 Spa2297_RS23840 9fafa612cbdf9500be0a0d57613a8a03 375 Pfam PF01148 Cytidylyltransferase family 116 371 6.2E-63 T 16-09-2016 Spa2297_RS28910 aea65c6d88fdf4c05a4f7737cc0f7ddd 424 Gene3D G3DSA:3.20.20.80 18 316 6.1E-22 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS28910 aea65c6d88fdf4c05a4f7737cc0f7ddd 424 SUPERFAMILY SSF51445 16 328 1.3E-32 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 Pfam PF07969 Amidohydrolase family 76 424 2.4E-21 T 16-09-2016 IPR013108 Amidohydrolase 3 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 SUPERFAMILY SSF51338 51 87 7.81E-8 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 SUPERFAMILY SSF51338 386 430 7.81E-8 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 PANTHER PTHR32027 74 431 1.6E-71 T 16-09-2016 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 SUPERFAMILY SSF51556 89 395 1.32E-63 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 PANTHER PTHR32027:SF9 74 431 1.6E-71 T 16-09-2016 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 Gene3D G3DSA:3.20.20.140 97 384 1.5E-90 T 16-09-2016 Spa2297_RS31530 80887d6aa56b639e46f54005538ea66d 431 Gene3D G3DSA:2.30.40.10 55 96 2.2E-6 T 16-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 Pfam PF00149 Calcineurin-like phosphoesterase 87 312 3.2E-5 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 SUPERFAMILY SSF56300 86 182 1.4E-26 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 SUPERFAMILY SSF56300 212 348 1.4E-26 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 Gene3D G3DSA:3.60.21.10 83 161 6.5E-27 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 Gene3D G3DSA:3.60.21.10 451 481 6.5E-27 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01905 a8067c4fa75bdf1a7197ebcbc185b919 500 Gene3D G3DSA:3.60.21.10 207 349 6.5E-27 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 300 1.3E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 198 212 1.3E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 326 340 1.3E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 262 282 1.3E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 302 325 1.3E-39 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 PIRSF PIRSF001134 1 364 6.5E-125 T 16-09-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 311 322 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Gene3D G3DSA:3.30.300.50 99 166 1.4E-5 T 16-09-2016 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Pfam PF02983 Alpha-lytic protease prodomain 100 153 6.0E-14 T 16-09-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 200 205 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 SUPERFAMILY SSF50494 180 354 6.78E-34 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Pfam PF00089 Trypsin 196 347 2.1E-9 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Gene3D G3DSA:2.40.10.10 257 348 1.2E-30 T 16-09-2016 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Gene3D G3DSA:2.40.10.10 173 246 1.6E-21 T 16-09-2016 Spa2297_RS30045 9f0546593fd44976c36fe6459485d609 446 Gene3D G3DSA:3.30.300.50 63 98 5.0E-4 T 16-09-2016 Spa2297_RS03455 a6cd28acf660d42d6cca637e349e64dc 195 Pfam PF16157 Domain of unknown function (DUF4865) 2 182 6.1E-65 T 16-09-2016 IPR032349 Protein of unknown function DUF4865 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 SMART SM00382 70 267 2.5E-20 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 Pfam PF00005 ABC transporter 62 209 2.7E-34 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 PANTHER PTHR24220:SF374 58 322 7.2E-151 T 16-09-2016 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 PANTHER PTHR24220:SF374 22 32 7.2E-151 T 16-09-2016 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 SUPERFAMILY SSF52540 57 286 2.82E-77 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 Gene3D G3DSA:3.40.50.300 56 282 3.8E-81 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 54 348 1.5E-108 T 16-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 PANTHER PTHR24220 58 322 7.2E-151 T 16-09-2016 Spa2297_RS20375 25dea883ad0c675a0c8f66d43a6ea571 404 PANTHER PTHR24220 22 32 7.2E-151 T 16-09-2016 Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 Gene3D G3DSA:3.30.565.10 252 397 1.9E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 SUPERFAMILY SSF55874 279 395 3.93E-13 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 394 2.8E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 PANTHER PTHR24423 179 518 4.5E-56 T 16-09-2016 Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 PANTHER PTHR24423 89 100 4.5E-56 T 16-09-2016 Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 PANTHER PTHR24423:SF523 179 518 4.5E-56 T 16-09-2016 Spa2297_RS28295 dfd0448436acd267008760f92aaa7823 646 PANTHER PTHR24423:SF523 89 100 4.5E-56 T 16-09-2016 Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 240 341 3.3E-14 T 16-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 SUPERFAMILY SSF53927 237 357 2.68E-25 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 Gene3D G3DSA:3.40.140.10 237 353 1.7E-20 T 16-09-2016 Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 Gene3D G3DSA:3.40.430.10 10 227 1.5E-53 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 SUPERFAMILY SSF53597 11 226 1.83E-43 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS15665 307033af69a8aa30a1dd559596a308db 386 Pfam PF01872 RibD C-terminal domain 12 221 1.4E-41 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 Pfam PF13432 Tetratricopeptide repeat 237 293 2.5E-7 T 16-09-2016 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 Pfam PF13432 Tetratricopeptide repeat 105 157 0.016 T 16-09-2016 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SUPERFAMILY SSF48452 231 441 7.82E-16 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SUPERFAMILY SSF81901 94 299 1.86E-11 T 16-09-2016 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SMART SM00028 126 159 300.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SMART SM00028 265 298 24.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SMART SM00028 407 440 15.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 SMART SM00028 231 264 0.11 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 Gene3D G3DSA:1.25.40.10 64 218 1.3E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 Gene3D G3DSA:1.25.40.10 226 442 2.9E-18 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 PANTHER PTHR23083 412 438 5.6E-18 T 16-09-2016 Spa2297_RS12525 95dc7f3c9449fd8486ea55ea5df27703 465 PANTHER PTHR23083 77 343 5.6E-18 T 16-09-2016 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 SUPERFAMILY SSF50182 161 218 6.54E-10 T 16-09-2016 IPR010920 LSM domain Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 SUPERFAMILY SSF82861 95 159 1.31E-9 T 16-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 PANTHER PTHR30460 27 348 7.5E-99 T 16-09-2016 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 Gene3D G3DSA:2.30.30.60 176 220 2.1E-10 T 16-09-2016 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 SUPERFAMILY SSF82689 225 318 1.23E-9 T 16-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 Gene3D G3DSA:3.30.70.100 232 316 1.8E-5 T 16-09-2016 Spa2297_RS11245 0256100a418f7902becd09f78bfb432a 366 Pfam PF00924 Mechanosensitive ion channel 119 318 3.7E-35 T 16-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Spa2297_RS05050 3017e8e1c5b9d63983687c86195f3966 125 Gene3D G3DSA:2.30.30.240 9 46 2.5E-4 T 16-09-2016 Spa2297_RS05050 3017e8e1c5b9d63983687c86195f3966 125 Pfam PF05239 PRC-barrel domain 8 64 7.7E-10 T 16-09-2016 IPR027275 PRC-barrel domain Spa2297_RS05050 3017e8e1c5b9d63983687c86195f3966 125 SUPERFAMILY SSF50346 5 106 7.33E-24 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 PANTHER PTHR22604 4 329 7.4E-109 T 16-09-2016 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 SUPERFAMILY SSF55347 130 295 2.45E-40 T 16-09-2016 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 PANTHER PTHR22604:SF105 4 329 7.4E-109 T 16-09-2016 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 122 5.6E-24 T 16-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 200 2.9E-6 T 16-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 SUPERFAMILY SSF51735 3 157 5.78E-53 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 Gene3D G3DSA:3.30.360.10 146 331 1.6E-51 T 16-09-2016 Spa2297_RS09535 2b38990976f0fb1126a33a3c705c6165 338 Gene3D G3DSA:3.40.50.720 3 145 1.6E-49 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 Pfam PF03717 Penicillin-binding Protein dimerisation domain 42 210 4.1E-17 T 16-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 SUPERFAMILY SSF56601 231 582 1.52E-86 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 PANTHER PTHR30627:SF1 1 595 1.2E-200 T 16-09-2016 Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 SUPERFAMILY SSF56519 39 230 1.7E-34 T 16-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 Gene3D G3DSA:3.40.710.10 238 576 1.5E-90 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 Gene3D G3DSA:3.90.1310.10 149 237 2.6E-25 T 16-09-2016 Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 PANTHER PTHR30627 1 595 1.2E-200 T 16-09-2016 Spa2297_RS08555 f4b91c9f683c2da671c5577cef52d089 595 Pfam PF00905 Penicillin binding protein transpeptidase domain 256 571 4.4E-73 T 16-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spa2297_RS04165 561b73cd738dbadcb87d8f6e0c872244 257 Pfam PF03707 Bacterial signalling protein N terminal repeat 55 112 1.3E-15 T 16-09-2016 IPR005330 MHYT domain Spa2297_RS04165 561b73cd738dbadcb87d8f6e0c872244 257 Pfam PF03707 Bacterial signalling protein N terminal repeat 119 174 1.8E-18 T 16-09-2016 IPR005330 MHYT domain Spa2297_RS04165 561b73cd738dbadcb87d8f6e0c872244 257 PANTHER PTHR35152 10 255 3.5E-58 T 16-09-2016 Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 PANTHER PTHR22748 2 267 8.0E-93 T 16-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 258 1.0E-26 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 264 2.3E-73 T 16-09-2016 Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 Gene3D G3DSA:3.60.10.10 2 266 3.1E-90 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 SUPERFAMILY SSF56219 2 266 2.62E-73 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS13815 38dea2efcd3a1bd9a28f9bd9bc34d604 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 265 8.9E-75 T 16-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Spa2297_RS06280 dd2c52fdb4d6fd2e7d3b444071fcabbb 323 Pfam PF00849 RNA pseudouridylate synthase 103 257 9.6E-14 T 16-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS06280 dd2c52fdb4d6fd2e7d3b444071fcabbb 323 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 142 156 - T 16-09-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS06280 dd2c52fdb4d6fd2e7d3b444071fcabbb 323 PANTHER PTHR11079 1 310 1.1E-149 T 16-09-2016 Spa2297_RS06280 dd2c52fdb4d6fd2e7d3b444071fcabbb 323 PANTHER PTHR11079:SF61 1 310 1.1E-149 T 16-09-2016 Spa2297_RS06280 dd2c52fdb4d6fd2e7d3b444071fcabbb 323 SUPERFAMILY SSF55120 95 308 1.01E-44 T 16-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 354 1.2E-26 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 112 3.3E-16 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 Gene3D G3DSA:1.20.140.10 218 356 2.2E-32 T 16-09-2016 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 SUPERFAMILY SSF47203 218 355 8.54E-32 T 16-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 SUPERFAMILY SSF56645 11 170 1.55E-18 T 16-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 Gene3D G3DSA:1.10.540.10 11 111 1.9E-17 T 16-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 PANTHER PTHR10909 9 355 5.6E-106 T 16-09-2016 Spa2297_RS04315 3ed812c3bd06415c60a5b840c1e3bb8a 362 PANTHER PTHR10909:SF302 9 355 5.6E-106 T 16-09-2016 Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 Gene3D G3DSA:2.30.110.10 6 134 4.2E-27 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 129 3.4E-31 T 16-09-2016 IPR019920 F420-binding domain, putative Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 PANTHER PTHR35176 1 136 6.9E-39 T 16-09-2016 Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 PANTHER PTHR35176:SF3 1 136 6.9E-39 T 16-09-2016 Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 SUPERFAMILY SSF50475 6 132 8.01E-27 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS29105 b5acb74a296dca8ca0583378c2e4b7ea 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 93 2.9E-11 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 PANTHER PTHR35344:SF3 3 126 6.8E-76 T 16-09-2016 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 51 64 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 Pfam PF00741 Gas vesicle protein 18 55 1.7E-12 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 18 32 - T 16-09-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 5 92 30.035 T 16-09-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 Spa2297_RS27065 ce5dbf61fa48d315c8d5156718be6e23 145 PANTHER PTHR35344 3 126 6.8E-76 T 16-09-2016 Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 PANTHER PTHR11732 4 95 1.6E-98 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 PANTHER PTHR11732:SF241 4 95 1.6E-98 T 16-09-2016 Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 Pfam PF00248 Aldo/keto reductase family 18 317 1.9E-44 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 PANTHER PTHR11732 111 329 1.6E-98 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 PANTHER PTHR11732:SF241 111 329 1.6E-98 T 16-09-2016 Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 SUPERFAMILY SSF51430 7 315 1.57E-61 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS31645 7cf16dda0b7fd02a94768092de587436 331 Gene3D G3DSA:3.20.20.100 7 314 1.3E-52 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS07240 7a704dafcbcbc1ad2718c0359c4cd36d 93 Pfam PF04226 Transglycosylase associated protein 33 79 5.3E-9 T 16-09-2016 IPR007341 Transglycosylase-associated protein GO:0016021 Spa2297_RS07240 7a704dafcbcbc1ad2718c0359c4cd36d 93 PANTHER PTHR33884 1 90 4.6E-32 T 16-09-2016 Spa2297_RS07240 7a704dafcbcbc1ad2718c0359c4cd36d 93 PANTHER PTHR33884:SF1 1 90 4.6E-32 T 16-09-2016 Spa2297_RS15015 128b12d4d9a9851ca67963d8069b2653 239 Gene3D G3DSA:3.10.350.10 184 233 1.8E-4 T 16-09-2016 IPR018392 LysM domain Spa2297_RS17285 2080dfc914a858a42645378b1caab3cc 342 PANTHER PTHR40053 1 310 1.0E-98 T 16-09-2016 Spa2297_RS17285 2080dfc914a858a42645378b1caab3cc 342 Pfam PF07070 SpoOM protein 3 217 2.0E-75 T 16-09-2016 IPR009776 Sporulation stage 0, protein M Spa2297_RS26630 b4fd66358e0cf1eb049f5d4ce5577718 87 SUPERFAMILY SSF47336 4 81 7.77E-10 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS26630 b4fd66358e0cf1eb049f5d4ce5577718 87 Gene3D G3DSA:1.10.1200.10 12 80 5.1E-11 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS03550 68ca5ec4651520ca3ec2d390892298c2 414 PANTHER PTHR24421 75 412 5.1E-104 T 16-09-2016 Spa2297_RS03550 68ca5ec4651520ca3ec2d390892298c2 414 Pfam PF07730 Histidine kinase 209 274 4.2E-21 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS03550 68ca5ec4651520ca3ec2d390892298c2 414 SUPERFAMILY SSF55874 293 403 3.44E-16 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS03550 68ca5ec4651520ca3ec2d390892298c2 414 PANTHER PTHR24421:SF26 75 412 5.1E-104 T 16-09-2016 Spa2297_RS03550 68ca5ec4651520ca3ec2d390892298c2 414 Gene3D G3DSA:3.30.565.10 291 411 1.6E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS07820 982400cd440957f15223695b9734d82c 246 SUPERFAMILY SSF100950 1 241 2.98E-61 T 16-09-2016 Spa2297_RS07820 982400cd440957f15223695b9734d82c 246 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 1 226 1.8E-72 T 16-09-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 Spa2297_RS07820 982400cd440957f15223695b9734d82c 246 PANTHER PTHR11054 1 241 2.7E-74 T 16-09-2016 Spa2297_RS07820 982400cd440957f15223695b9734d82c 246 Gene3D G3DSA:3.40.50.1360 3 236 4.7E-74 T 16-09-2016 Spa2297_RS07820 982400cd440957f15223695b9734d82c 246 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 1 236 1.0E-80 T 16-09-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31|UniPathway: UPA00115 Spa2297_RS01340 e6f6be5bfe503db6823adb6d709a3f4f 191 SUPERFAMILY SSF158682 56 190 8.63E-24 T 16-09-2016 IPR029024 TerB-like Spa2297_RS01340 e6f6be5bfe503db6823adb6d709a3f4f 191 Pfam PF05099 Tellurite resistance protein TerB 57 189 5.5E-31 T 16-09-2016 IPR007791 Co-chaperone DjlA, N-terminal Spa2297_RS01340 e6f6be5bfe503db6823adb6d709a3f4f 191 Gene3D G3DSA:1.10.3680.10 55 189 1.4E-24 T 16-09-2016 IPR029024 TerB-like Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 PANTHER PTHR24220 14 386 4.6E-189 T 16-09-2016 Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 Gene3D G3DSA:3.40.50.300 261 493 1.6E-48 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 SMART SM00382 37 225 2.4E-10 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 SMART SM00382 286 480 2.5E-6 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 PANTHER PTHR24220:SF308 14 386 4.6E-189 T 16-09-2016 Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 Gene3D G3DSA:3.40.50.300 10 243 7.8E-60 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 Pfam PF00005 ABC transporter 28 178 3.4E-28 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 Pfam PF00005 ABC transporter 278 431 2.3E-20 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 SUPERFAMILY SSF52540 11 236 8.3E-58 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29655 8c098a3098341827a3eecfdbd764085b 505 SUPERFAMILY SSF52540 275 484 1.45E-45 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 Gene3D G3DSA:1.10.10.10 5 73 8.9E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 SUPERFAMILY SSF48008 103 228 7.06E-24 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 SMART SM00345 13 71 1.2E-8 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 SMART SM00895 104 225 2.7E-23 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 PANTHER PTHR11751 102 120 7.4E-17 T 16-09-2016 Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 PANTHER PTHR11751 12 78 7.4E-17 T 16-09-2016 Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 SUPERFAMILY SSF46785 3 75 2.93E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 4.9E-12 T 16-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 Pfam PF07729 FCD domain 105 224 5.1E-24 T 16-09-2016 IPR011711 GntR, C-terminal Spa2297_RS29430 bc23dd793f96c66cce35c52d0ab8132c 237 Gene3D G3DSA:1.20.120.530 102 229 2.0E-24 T 16-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.2E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.2E-6 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.0E-11 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 SUPERFAMILY SSF46689 4 81 1.13E-16 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 Gene3D G3DSA:1.10.357.10 9 176 1.5E-29 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 SUPERFAMILY SSF48498 94 175 4.67E-5 T 16-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 PANTHER PTHR30055:SF91 1 177 1.0E-78 T 16-09-2016 Spa2297_RS01165 0bb6a4617f988637a52d2635a09a253f 185 PANTHER PTHR30055 1 177 1.0E-78 T 16-09-2016 Spa2297_RS15880 734eea01719513da4e7f197d9b7b6155 188 PANTHER PTHR34820 30 188 6.5E-63 T 16-09-2016 Spa2297_RS15880 734eea01719513da4e7f197d9b7b6155 188 PANTHER PTHR34820:SF2 30 188 6.5E-63 T 16-09-2016 Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 Gene3D G3DSA:1.10.150.240 26 77 5.5E-4 T 16-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 Gene3D G3DSA:3.40.50.1000 78 215 3.4E-15 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 PANTHER PTHR18901 7 222 3.6E-73 T 16-09-2016 Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 SUPERFAMILY SSF56784 8 215 2.47E-29 T 16-09-2016 IPR023214 HAD-like domain Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 180 9.5E-10 T 16-09-2016 Spa2297_RS12960 196d8f3be1df19fe6ff84865b21bf355 223 PANTHER PTHR18901:SF40 7 222 3.6E-73 T 16-09-2016 Spa2297_RS21495 8263a0af96a2da0a3e3de5d7d9f3ce99 399 Pfam PF13845 Septum formation 142 249 1.9E-10 T 16-09-2016 IPR026004 Septum formation-related domain Spa2297_RS21495 8263a0af96a2da0a3e3de5d7d9f3ce99 399 Pfam PF13828 Domain of unknown function (DUF4190) 57 112 1.0E-16 T 16-09-2016 IPR025241 Domain of unknown function DUF4190 Spa2297_RS14995 f208f9af4d32c5aed21028040f76d0ca 148 PANTHER PTHR38009:SF1 1 148 2.8E-37 T 16-09-2016 Spa2297_RS14995 f208f9af4d32c5aed21028040f76d0ca 148 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 147 1.4E-37 T 16-09-2016 IPR011747 Conserved hypothetical protein CHP02241 Spa2297_RS14995 f208f9af4d32c5aed21028040f76d0ca 148 Pfam PF06841 T4-like virus tail tube protein gp19 11 145 5.9E-28 T 16-09-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 Spa2297_RS14995 f208f9af4d32c5aed21028040f76d0ca 148 PANTHER PTHR38009 1 148 2.8E-37 T 16-09-2016 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 Gene3D G3DSA:3.30.465.10 120 233 6.1E-7 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 PANTHER PTHR11748:SF33 37 526 2.6E-100 T 16-09-2016 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 Pfam PF01565 FAD binding domain 61 195 5.2E-24 T 16-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 SUPERFAMILY SSF56176 41 233 5.14E-37 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 PANTHER PTHR11748 37 526 2.6E-100 T 16-09-2016 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 Pfam PF08031 Berberine and berberine like 474 527 3.5E-16 T 16-09-2016 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 Spa2297_RS23965 d94d54c4d690dc3801ad0fabff2e4b60 534 Gene3D G3DSA:3.30.43.10 60 117 1.2E-11 T 16-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 Gene3D G3DSA:1.20.1200.10 16 187 6.1E-54 T 16-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 1.0E-93 T 16-09-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 PANTHER PTHR12213 1 185 1.4E-67 T 16-09-2016 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 1.2E-51 T 16-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 SUPERFAMILY SSF89028 6 185 2.75E-54 T 16-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 Spa2297_RS22735 8a38d15aa6ddcd97c0091126a9ac1b81 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 182 1.1E-47 T 16-09-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 Spa2297_RS23085 2ff40291968259a8705cbf092969ac68 211 SUPERFAMILY SSF56399 82 211 8.63E-35 T 16-09-2016 Spa2297_RS23085 2ff40291968259a8705cbf092969ac68 211 Gene3D G3DSA:3.90.210.10 84 209 3.5E-24 T 16-09-2016 Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 Gene3D G3DSA:3.10.180.10 85 155 2.5E-7 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 PANTHER PTHR35908 7 39 3.2E-40 T 16-09-2016 Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 PANTHER PTHR35908 73 156 3.2E-40 T 16-09-2016 Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 SUPERFAMILY SSF54593 68 155 9.13E-6 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 SUPERFAMILY SSF54593 25 41 9.13E-6 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 PANTHER PTHR35908:SF1 7 39 3.2E-40 T 16-09-2016 Spa2297_RS19405 17f6c541753589e164e5846c82c460ed 156 PANTHER PTHR35908:SF1 73 156 3.2E-40 T 16-09-2016 Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 Gene3D G3DSA:3.40.50.270 7 132 1.5E-40 T 16-09-2016 Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 PANTHER PTHR11717 2 138 8.5E-40 T 16-09-2016 Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 SMART SM00226 8 133 1.6E-43 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 SUPERFAMILY SSF52788 8 132 1.02E-36 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 130 4.2E-23 T 16-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily Spa2297_RS14080 9fcef7bf01d1070d8ce61fa23e9945d7 140 PANTHER PTHR11717:SF18 2 138 8.5E-40 T 16-09-2016 Spa2297_RS11930 59f43b35785a57ab212fc38a3da0f153 451 Pfam PF13245 Part of AAA domain 30 95 1.1E-10 T 16-09-2016 Spa2297_RS11930 59f43b35785a57ab212fc38a3da0f153 451 Gene3D G3DSA:3.40.50.300 21 236 3.2E-18 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11930 59f43b35785a57ab212fc38a3da0f153 451 SUPERFAMILY SSF52540 29 403 1.36E-26 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS23745 2ba747c0238e2c064cfe3335b783b10f 79 PANTHER PTHR34654 1 79 3.2E-26 T 16-09-2016 Spa2297_RS23745 2ba747c0238e2c064cfe3335b783b10f 79 Pfam PF13083 KH domain 3 65 2.3E-19 T 16-09-2016 Spa2297_RS23745 2ba747c0238e2c064cfe3335b783b10f 79 SUPERFAMILY SSF54814 16 62 1.96E-8 T 16-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 Spa2297_RS23745 2ba747c0238e2c064cfe3335b783b10f 79 Hamap MF_00088 UPF0109 protein . 2 73 21.613 T 16-09-2016 IPR020627 Uncharacterised protein family UPF0109 Spa2297_RS23745 2ba747c0238e2c064cfe3335b783b10f 79 Gene3D G3DSA:3.30.300.120 5 63 9.8E-6 T 16-09-2016 Spa2297_RS23870 4eaaf49aea837caa32ad0919d0e3a14c 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 125 4.9E-7 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS23870 4eaaf49aea837caa32ad0919d0e3a14c 135 SUPERFAMILY SSF54593 4 131 1.79E-21 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS23870 4eaaf49aea837caa32ad0919d0e3a14c 135 PANTHER PTHR36503:SF2 2 134 4.4E-68 T 16-09-2016 Spa2297_RS23870 4eaaf49aea837caa32ad0919d0e3a14c 135 Gene3D G3DSA:3.10.180.10 3 131 6.1E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS23870 4eaaf49aea837caa32ad0919d0e3a14c 135 PANTHER PTHR36503 2 134 4.4E-68 T 16-09-2016 Spa2297_RS20240 a74f8eac2b9f6df5b031dfb49b8ebdf9 398 PANTHER PTHR21666 260 387 3.0E-36 T 16-09-2016 Spa2297_RS20240 a74f8eac2b9f6df5b031dfb49b8ebdf9 398 Gene3D G3DSA:3.90.1720.10 280 384 2.0E-42 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS20240 a74f8eac2b9f6df5b031dfb49b8ebdf9 398 SUPERFAMILY SSF54001 278 384 5.4E-40 T 16-09-2016 Spa2297_RS20240 a74f8eac2b9f6df5b031dfb49b8ebdf9 398 Pfam PF00877 NlpC/P60 family 295 380 1.9E-24 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 Pfam PF13439 Glycosyltransferase Family 4 20 199 3.9E-38 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 Gene3D G3DSA:3.40.50.2000 184 376 6.7E-30 T 16-09-2016 Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 PANTHER PTHR12526:SF374 1 395 2.0E-75 T 16-09-2016 Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 SUPERFAMILY SSF53756 19 395 2.46E-85 T 16-09-2016 Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 Pfam PF00534 Glycosyl transferases group 1 230 376 1.4E-32 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS26205 fc21819b1ec64965e2388bbf057d30ad 395 PANTHER PTHR12526 1 395 2.0E-75 T 16-09-2016 Spa2297_RS25250 7c58c63bd933fea4e03117d6b3c9623a 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 300 3.7E-16 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25250 7c58c63bd933fea4e03117d6b3c9623a 308 SUPERFAMILY SSF161098 51 294 4.06E-50 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25250 7c58c63bd933fea4e03117d6b3c9623a 308 Gene3D G3DSA:1.10.3720.10 57 304 2.0E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS25250 7c58c63bd933fea4e03117d6b3c9623a 308 PANTHER PTHR30193:SF15 7 305 1.4E-81 T 16-09-2016 Spa2297_RS25250 7c58c63bd933fea4e03117d6b3c9623a 308 PANTHER PTHR30193 7 305 1.4E-81 T 16-09-2016 Spa2297_RS02695 fb8d8b930d4774ecca3a9e080861cdde 78 SUPERFAMILY SSF47336 5 74 2.02E-7 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02695 fb8d8b930d4774ecca3a9e080861cdde 78 Gene3D G3DSA:1.10.1200.10 4 72 1.4E-6 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS27085 c66f75c6a163552f6e8d7dabfd83d80f 394 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 138 255 8.8E-13 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS27085 c66f75c6a163552f6e8d7dabfd83d80f 394 PANTHER PTHR33824:SF2 1 296 9.7E-137 T 16-09-2016 Spa2297_RS27085 c66f75c6a163552f6e8d7dabfd83d80f 394 SUPERFAMILY SSF55961 136 251 6.65E-15 T 16-09-2016 Spa2297_RS27085 c66f75c6a163552f6e8d7dabfd83d80f 394 PANTHER PTHR33824 1 296 9.7E-137 T 16-09-2016 Spa2297_RS13900 1013e772626a86da00eedf92e4156379 344 SUPERFAMILY SSF56266 3 336 2.62E-71 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS13900 1013e772626a86da00eedf92e4156379 344 PANTHER PTHR36512:SF3 3 344 1.7E-146 T 16-09-2016 Spa2297_RS13900 1013e772626a86da00eedf92e4156379 344 Pfam PF03576 Peptidase family S58 4 333 8.7E-72 T 16-09-2016 IPR005321 Peptidase S58, DmpA Spa2297_RS13900 1013e772626a86da00eedf92e4156379 344 PANTHER PTHR36512 3 344 1.7E-146 T 16-09-2016 Spa2297_RS13900 1013e772626a86da00eedf92e4156379 344 Gene3D G3DSA:3.60.70.12 4 334 9.6E-89 T 16-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 Spa2297_RS27625 53a7f0a70f3f1475ad9ae1be41a0587a 330 PANTHER PTHR11695 18 314 4.4E-17 T 16-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 Spa2297_RS27625 53a7f0a70f3f1475ad9ae1be41a0587a 330 Gene3D G3DSA:3.90.180.10 6 147 3.4E-10 T 16-09-2016 IPR011032 GroES-like Spa2297_RS27625 53a7f0a70f3f1475ad9ae1be41a0587a 330 SUPERFAMILY SSF51735 121 268 8.74E-19 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27625 53a7f0a70f3f1475ad9ae1be41a0587a 330 Gene3D G3DSA:3.40.50.720 148 257 1.2E-12 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS27625 53a7f0a70f3f1475ad9ae1be41a0587a 330 SUPERFAMILY SSF50129 5 155 1.57E-16 T 16-09-2016 IPR011032 GroES-like Spa2297_RS30490 68811cbe0d38eb8ea1777e44458682a4 89 PANTHER PTHR33884 1 88 1.7E-23 T 16-09-2016 Spa2297_RS30490 68811cbe0d38eb8ea1777e44458682a4 89 Pfam PF04226 Transglycosylase associated protein 33 83 9.7E-10 T 16-09-2016 IPR007341 Transglycosylase-associated protein GO:0016021 Spa2297_RS22875 91d405023cf2f5e52a24f5e10f7067a9 114 Pfam PF12823 Domain of unknown function (DUF3817) 9 95 1.3E-21 T 16-09-2016 IPR023845 Domain of unknown function DUF3817, transmembrane Spa2297_RS22875 91d405023cf2f5e52a24f5e10f7067a9 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 93 2.8E-22 T 16-09-2016 IPR023845 Domain of unknown function DUF3817, transmembrane Spa2297_RS22875 91d405023cf2f5e52a24f5e10f7067a9 114 PANTHER PTHR40077 2 112 3.5E-33 T 16-09-2016 Spa2297_RS27475 627f624a6587b219a084eafbfe3d280e 620 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 19 421 5.4E-112 T 16-09-2016 IPR026337 HEXXH motif domain Spa2297_RS12005 97f9f39dc96b8187160a98c953a222af 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 6.0E-9 T 16-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spa2297_RS12005 97f9f39dc96b8187160a98c953a222af 121 PIRSF PIRSF039020 1 121 3.2E-43 T 16-09-2016 IPR026275 Glyoxalase/bleomycin resistance protein/dioxygenase Spa2297_RS12005 97f9f39dc96b8187160a98c953a222af 121 SUPERFAMILY SSF54593 8 118 2.34E-21 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS12005 97f9f39dc96b8187160a98c953a222af 121 Gene3D G3DSA:3.10.180.10 7 117 2.6E-21 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 PANTHER PTHR30061:SF1 1 437 2.5E-64 T 16-09-2016 Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 PANTHER PTHR30061 1 437 2.5E-64 T 16-09-2016 Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 SUPERFAMILY SSF53850 43 428 1.99E-50 T 16-09-2016 Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 Gene3D G3DSA:3.40.190.10 59 173 2.5E-9 T 16-09-2016 Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 Pfam PF01547 Bacterial extracellular solute-binding protein 55 347 2.0E-46 T 16-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 Spa2297_RS00345 690511e9e9cdfa9360b29df5d68d0678 437 Gene3D G3DSA:3.40.190.10 174 352 3.2E-27 T 16-09-2016 Spa2297_RS02150 6f3eca417adda54e5e00be4166fa3ca8 84 PANTHER PTHR38839:SF3 3 77 1.5E-30 T 16-09-2016 Spa2297_RS02150 6f3eca417adda54e5e00be4166fa3ca8 84 Pfam PF02467 Transcription factor WhiB 4 72 2.8E-26 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS02150 6f3eca417adda54e5e00be4166fa3ca8 84 PANTHER PTHR38839 3 77 1.5E-30 T 16-09-2016 Spa2297_RS02150 6f3eca417adda54e5e00be4166fa3ca8 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 2 80 14.588 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS16150 b16bdf06a5f37e9b3d66da9987ad7ec2 329 SUPERFAMILY SSF103642 32 51 9.48E-7 T 16-09-2016 Spa2297_RS16150 b16bdf06a5f37e9b3d66da9987ad7ec2 329 Gene3D G3DSA:3.10.450.50 24 51 7.2E-8 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS16150 b16bdf06a5f37e9b3d66da9987ad7ec2 329 Pfam PF02810 SEC-C motif 35 51 5.5E-8 T 16-09-2016 IPR004027 SEC-C motif Spa2297_RS12445 ffa2f2746c3901aafaa0dd42b9473ca7 154 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 57 150 1.8E-8 T 16-09-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 Spa2297_RS12445 ffa2f2746c3901aafaa0dd42b9473ca7 154 SUPERFAMILY SSF50118 53 151 6.76E-10 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS12445 ffa2f2746c3901aafaa0dd42b9473ca7 154 Gene3D G3DSA:2.30.30.110 53 151 2.4E-4 T 16-09-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 PANTHER PTHR12176:SF22 125 435 3.2E-33 T 16-09-2016 Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 SUPERFAMILY SSF103473 26 204 2.62E-6 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 Gene3D G3DSA:3.40.50.150 232 500 1.1E-68 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 SUPERFAMILY SSF53335 232 456 6.54E-27 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 Gene3D G3DSA:1.20.1250.20 40 202 3.3E-5 T 16-09-2016 Spa2297_RS17320 d4965f1b8d03329204d519c6542632fc 512 PANTHER PTHR12176 125 435 3.2E-33 T 16-09-2016 Spa2297_RS05085 854c4369438e9aa189a42c6246f7b019 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 8.1E-35 T 16-09-2016 IPR009709 Protein of unknown function DUF1290 Spa2297_RS05085 854c4369438e9aa189a42c6246f7b019 110 PIRSF PIRSF018579 1 110 4.5E-47 T 16-09-2016 IPR009709 Protein of unknown function DUF1290 Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 Pfam PF01551 Peptidase family M23 171 242 2.2E-16 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 Gene3D G3DSA:2.70.70.10 66 243 3.2E-25 T 16-09-2016 Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 SUPERFAMILY SSF51261 133 148 1.83E-20 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 SUPERFAMILY SSF51261 179 243 1.83E-20 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 PANTHER PTHR21666 183 274 1.1E-14 T 16-09-2016 Spa2297_RS15780 0b374800bfc45155bb88b5b49c2600e3 278 PANTHER PTHR21666 134 152 1.1E-14 T 16-09-2016 Spa2297_RS09165 5690f366e4df83d3c05e6707f9f7faff 709 SUPERFAMILY SSF52540 345 549 2.89E-11 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS09165 5690f366e4df83d3c05e6707f9f7faff 709 Pfam PF01580 FtsK/SpoIIIE family 365 487 2.2E-6 T 16-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spa2297_RS09165 5690f366e4df83d3c05e6707f9f7faff 709 Gene3D G3DSA:3.40.50.300 368 541 1.5E-7 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS21930 5d2f8f473bb2adb784f270e8e2cf318f 467 PANTHER PTHR10566 1 449 6.6E-275 T 16-09-2016 Spa2297_RS21930 5d2f8f473bb2adb784f270e8e2cf318f 467 SUPERFAMILY SSF56112 195 312 3.37E-20 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS21930 5d2f8f473bb2adb784f270e8e2cf318f 467 SUPERFAMILY SSF56112 95 158 3.37E-20 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS21930 5d2f8f473bb2adb784f270e8e2cf318f 467 PANTHER PTHR10566:SF64 1 449 6.6E-275 T 16-09-2016 Spa2297_RS21930 5d2f8f473bb2adb784f270e8e2cf318f 467 Pfam PF03109 ABC1 family 113 227 6.2E-30 T 16-09-2016 IPR004147 UbiB domain Spa2297_RS20620 c1399ba4128cbfb7e2fcbb8e4b606128 321 PANTHER PTHR22916 2 266 1.9E-40 T 16-09-2016 Spa2297_RS20620 c1399ba4128cbfb7e2fcbb8e4b606128 321 Gene3D G3DSA:3.90.550.10 2 200 1.5E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20620 c1399ba4128cbfb7e2fcbb8e4b606128 321 PANTHER PTHR22916:SF23 2 266 1.9E-40 T 16-09-2016 Spa2297_RS20620 c1399ba4128cbfb7e2fcbb8e4b606128 321 SUPERFAMILY SSF53448 2 228 3.02E-45 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20620 c1399ba4128cbfb7e2fcbb8e4b606128 321 Pfam PF00535 Glycosyl transferase family 2 5 125 3.0E-31 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS21780 78cfeaa412084c088037afd27323bb4e 201 Pfam PF01914 MarC family integral membrane protein 5 197 6.0E-47 T 16-09-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Spa2297_RS21780 78cfeaa412084c088037afd27323bb4e 201 PANTHER PTHR33508 1 199 3.7E-72 T 16-09-2016 Spa2297_RS21780 78cfeaa412084c088037afd27323bb4e 201 PANTHER PTHR33508:SF1 1 199 3.7E-72 T 16-09-2016 Spa2297_RS21780 78cfeaa412084c088037afd27323bb4e 201 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 194 2.2E-44 T 16-09-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 PIRSF PIRSF000412 1 413 2.7E-156 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 Gene3D G3DSA:3.40.640.10 37 282 2.7E-105 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 SUPERFAMILY SSF53383 4 416 3.71E-171 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 Gene3D G3DSA:3.90.1150.10 283 416 6.7E-46 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 PANTHER PTHR11680 3 415 5.8E-242 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 Pfam PF00464 Serine hydroxymethyltransferase 9 388 4.6E-162 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 50.034 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS23125 6579ebdb21c21068546b39248dbcc496 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 16-09-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 SUPERFAMILY SSF55486 213 404 1.17E-15 T 16-09-2016 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 PIRSF PIRSF007519 1 779 1.4E-238 T 16-09-2016 IPR012300 Peptidase M6, InhA Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 PANTHER PTHR22935:SF71 153 489 2.5E-230 T 16-09-2016 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 Pfam PF05547 Immune inhibitor A peptidase M6 101 773 3.1E-269 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 PANTHER PTHR22935 153 489 2.5E-230 T 16-09-2016 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 153 456 3.7E-83 T 16-09-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 Gene3D G3DSA:3.40.390.10 221 263 5.1E-26 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS12495 790b715078c9b4d0aba855f5ef30c76e 781 Gene3D G3DSA:3.40.390.10 326 404 5.1E-26 T 16-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 Spa2297_RS00020 ca2cbf8e40a0f2ca68216bc9f819fe1d 299 SUPERFAMILY SSF111331 68 211 8.83E-14 T 16-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain Spa2297_RS00020 ca2cbf8e40a0f2ca68216bc9f819fe1d 299 Gene3D G3DSA:3.40.50.10330 66 161 8.5E-5 T 16-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS00020 ca2cbf8e40a0f2ca68216bc9f819fe1d 299 Gene3D G3DSA:2.60.200.30 162 211 2.1E-7 T 16-09-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 Spa2297_RS06520 5015bbe61ed6579ca37c1a77bc91d718 286 Pfam PF03777 Small secreted domain (DUF320) 102 156 5.6E-25 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS06520 5015bbe61ed6579ca37c1a77bc91d718 286 Pfam PF03777 Small secreted domain (DUF320) 24 79 8.3E-28 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS25025 2f227dba72d688a66f30ff86ba8afd5e 192 Gene3D G3DSA:1.10.357.10 4 168 2.3E-24 T 16-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 Spa2297_RS25025 2f227dba72d688a66f30ff86ba8afd5e 192 SUPERFAMILY SSF46689 5 64 4.99E-11 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS25025 2f227dba72d688a66f30ff86ba8afd5e 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 51 2.0E-8 T 16-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spa2297_RS22880 489b839d588b46a0b5c3de51e1110ff2 97 SUPERFAMILY SSF89957 1 95 1.44E-29 T 16-09-2016 IPR029756 MTH1187/YkoF-like Spa2297_RS22880 489b839d588b46a0b5c3de51e1110ff2 97 PANTHER PTHR33777 1 97 1.2E-30 T 16-09-2016 Spa2297_RS22880 489b839d588b46a0b5c3de51e1110ff2 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 1.5E-18 T 16-09-2016 IPR002767 Thiamine-binding protein Spa2297_RS22880 489b839d588b46a0b5c3de51e1110ff2 97 Gene3D G3DSA:3.30.70.930 1 92 1.3E-34 T 16-09-2016 IPR029756 MTH1187/YkoF-like Spa2297_RS22880 489b839d588b46a0b5c3de51e1110ff2 97 Pfam PF01910 Thiamine-binding protein 3 92 1.3E-29 T 16-09-2016 IPR002767 Thiamine-binding protein Spa2297_RS10155 3d2ed383750d1b55eb92241a51fb670b 182 PANTHER PTHR37042 4 175 1.2E-39 T 16-09-2016 Spa2297_RS10155 3d2ed383750d1b55eb92241a51fb670b 182 SUPERFAMILY SSF54427 70 171 3.83E-5 T 16-09-2016 IPR032710 NTF2-like domain Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 PANTHER PTHR38444:SF1 1 71 2.4E-35 T 16-09-2016 Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 SMART SM00923 3 53 4.0E-30 T 16-09-2016 IPR005153 MbtH-like protein Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 Gene3D G3DSA:3.90.820.10 10 69 3.4E-28 T 16-09-2016 Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 PANTHER PTHR38444 1 71 2.4E-35 T 16-09-2016 Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 Pfam PF03621 MbtH-like protein 2 52 4.4E-27 T 16-09-2016 IPR005153 MbtH-like protein Spa2297_RS00520 b9dc110c03afa2b7f81dfdf403b56c80 72 SUPERFAMILY SSF160582 2 67 1.44E-28 T 16-09-2016 Spa2297_RS16405 812b2ba799ed48f157648e766d5ffe37 150 Pfam PF00583 Acetyltransferase (GNAT) family 58 139 5.3E-15 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS16405 812b2ba799ed48f157648e766d5ffe37 150 Gene3D G3DSA:3.40.630.30 2 149 3.4E-45 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16405 812b2ba799ed48f157648e766d5ffe37 150 PANTHER PTHR23091 1 139 3.3E-22 T 16-09-2016 Spa2297_RS16405 812b2ba799ed48f157648e766d5ffe37 150 SUPERFAMILY SSF55729 1 144 1.4E-29 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS12685 91b1dc9287bad18c46910fead489b885 221 Gene3D G3DSA:3.40.50.620 18 152 7.3E-41 T 16-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spa2297_RS12685 91b1dc9287bad18c46910fead489b885 221 PANTHER PTHR30336:SF5 2 221 1.2E-79 T 16-09-2016 Spa2297_RS12685 91b1dc9287bad18c46910fead489b885 221 PANTHER PTHR30336 2 221 1.2E-79 T 16-09-2016 Spa2297_RS12685 91b1dc9287bad18c46910fead489b885 221 Pfam PF02698 DUF218 domain 32 151 6.1E-20 T 16-09-2016 IPR003848 Domain of unknown function DUF218 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 SUPERFAMILY SSF53474 110 156 1.14E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 SUPERFAMILY SSF53474 199 471 1.14E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 Gene3D G3DSA:3.40.50.1820 202 308 1.4E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 Gene3D G3DSA:3.40.50.1820 357 499 1.4E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 Gene3D G3DSA:3.40.50.1820 75 158 1.4E-53 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992 204 292 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992 41 157 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992 385 501 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992:SF878 204 292 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992:SF878 41 157 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 PANTHER PTHR10992:SF878 385 501 2.3E-64 T 16-09-2016 Spa2297_RS21865 8c361e582a723c5f282a8d7f987800b3 512 Pfam PF08386 TAP-like protein 406 511 4.4E-33 T 16-09-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 Pfam PF00171 Aldehyde dehydrogenase family 34 477 6.9E-166 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 Gene3D G3DSA:3.40.605.10 22 271 1.1E-99 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 PANTHER PTHR11699:SF46 3 478 3.1E-224 T 16-09-2016 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 SUPERFAMILY SSF53720 20 477 1.31E-164 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 PANTHER PTHR11699 3 478 3.1E-224 T 16-09-2016 Spa2297_RS20795 56a040f22f1902c0b439c27b5a031ac7 478 Gene3D G3DSA:3.40.309.10 272 456 1.4E-63 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS17790 57ecbba41360dc054025ed3cbe645eb8 103 Pfam PF17032 zinc-ribbon family 19 75 2.4E-9 T 16-09-2016 IPR031493 Zinc-ribbon 15 Spa2297_RS10445 6ddeed421b9f9deabca97f9b58fed438 139 Gene3D G3DSA:3.10.490.10 7 136 1.7E-27 T 16-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like Spa2297_RS10445 6ddeed421b9f9deabca97f9b58fed438 139 SUPERFAMILY SSF110857 6 124 1.83E-24 T 16-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like Spa2297_RS10445 6ddeed421b9f9deabca97f9b58fed438 139 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 8 136 4.4E-24 T 16-09-2016 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like Spa2297_RS30925 cad9d8036f9294d5468475c5f42cf16d 276 PANTHER PTHR35273:SF2 1 276 3.6E-73 T 16-09-2016 Spa2297_RS30925 cad9d8036f9294d5468475c5f42cf16d 276 SUPERFAMILY SSF51445 51 251 3.37E-21 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS30925 cad9d8036f9294d5468475c5f42cf16d 276 PANTHER PTHR35273 1 276 3.6E-73 T 16-09-2016 Spa2297_RS30925 cad9d8036f9294d5468475c5f42cf16d 276 Pfam PF03537 Glycoside-hydrolase family GH114 51 263 2.3E-52 T 16-09-2016 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain Spa2297_RS14640 32e849f0bdfc137d7cb5e40c0053de6e 307 Pfam PF11228 Protein of unknown function (DUF3027) 36 261 6.4E-83 T 16-09-2016 IPR021391 Protein of unknown function DUF3027 Spa2297_RS09485 9a5a3fc66a79e3cea6a92114a6a2a2e3 475 Pfam PF04213 Htaa 238 386 5.1E-44 T 16-09-2016 IPR007331 Htaa Spa2297_RS09485 9a5a3fc66a79e3cea6a92114a6a2a2e3 475 Pfam PF04213 Htaa 35 201 6.5E-52 T 16-09-2016 IPR007331 Htaa Spa2297_RS17845 9d1c1be1a9b4e3a27f89cc382dceae8d 155 SUPERFAMILY SSF55298 1 152 6.75E-57 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS17845 9d1c1be1a9b4e3a27f89cc382dceae8d 155 Gene3D G3DSA:3.30.1330.40 1 152 4.7E-68 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS17845 9d1c1be1a9b4e3a27f89cc382dceae8d 155 PANTHER PTHR11803 1 152 1.2E-51 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS17845 9d1c1be1a9b4e3a27f89cc382dceae8d 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 151 6.4E-33 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS17845 9d1c1be1a9b4e3a27f89cc382dceae8d 155 PANTHER PTHR11803:SF2 1 152 1.2E-51 T 16-09-2016 Spa2297_RS02730 f312cbde63534b4819d020a6a3f4329e 291 Pfam PF00535 Glycosyl transferase family 2 11 136 6.3E-8 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS02730 f312cbde63534b4819d020a6a3f4329e 291 Gene3D G3DSA:3.90.550.10 14 202 1.3E-21 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS02730 f312cbde63534b4819d020a6a3f4329e 291 PANTHER PTHR22916 15 257 5.9E-23 T 16-09-2016 Spa2297_RS02730 f312cbde63534b4819d020a6a3f4329e 291 SUPERFAMILY SSF53448 10 219 3.46E-32 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS00640 09646624a93e36750f87d3eb6e467b00 368 PANTHER PTHR30472:SF32 18 363 1.8E-163 T 16-09-2016 Spa2297_RS00640 09646624a93e36750f87d3eb6e467b00 368 Gene3D G3DSA:1.10.3470.10 29 361 5.9E-107 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS00640 09646624a93e36750f87d3eb6e467b00 368 SUPERFAMILY SSF81345 27 357 2.75E-81 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS00640 09646624a93e36750f87d3eb6e467b00 368 Pfam PF01032 FecCD transport family 36 357 3.9E-92 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS00640 09646624a93e36750f87d3eb6e467b00 368 PANTHER PTHR30472 18 363 1.8E-163 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS17625 68e952572dac0d5f318e58998b218aac 452 SUPERFAMILY SSF55874 314 429 2.37E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17625 68e952572dac0d5f318e58998b218aac 452 PANTHER PTHR24421 118 445 1.2E-109 T 16-09-2016 Spa2297_RS17625 68e952572dac0d5f318e58998b218aac 452 PANTHER PTHR24421:SF26 118 445 1.2E-109 T 16-09-2016 Spa2297_RS17625 68e952572dac0d5f318e58998b218aac 452 Pfam PF07730 Histidine kinase 221 285 6.8E-21 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS08580 3ef1bf0ab9084934d500257581ed0bef 453 Pfam PF01882 Protein of unknown function DUF58 220 298 2.8E-20 T 16-09-2016 IPR002881 Domain of unknown function DUF58 Spa2297_RS08580 3ef1bf0ab9084934d500257581ed0bef 453 PANTHER PTHR34351:SF1 12 425 2.6E-119 T 16-09-2016 Spa2297_RS08580 3ef1bf0ab9084934d500257581ed0bef 453 PANTHER PTHR34351 12 425 2.6E-119 T 16-09-2016 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 176 201 - T 16-09-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 PANTHER PTHR31480 15 316 6.0E-142 T 16-09-2016 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 26 298 1.1E-96 T 16-09-2016 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 141 156 - T 16-09-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 SUPERFAMILY SSF48576 18 306 4.53E-75 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 PANTHER PTHR31480:SF5 15 316 6.0E-142 T 16-09-2016 Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 Gene3D G3DSA:1.10.600.10 16 313 2.8E-83 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28160 868e5838ba7f7e0ce2a88d1c12d8c6c3 316 Pfam PF00494 Squalene/phytoene synthase 28 289 7.6E-74 T 16-09-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 75 182 8.1E-28 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 SUPERFAMILY SSF55486 71 353 1.65E-80 T 16-09-2016 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 185 353 1.5E-49 T 16-09-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 173 189 1.6E-28 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 194 205 1.6E-28 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 137 157 1.6E-28 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 275 291 1.6E-28 T 16-09-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 Gene3D G3DSA:3.10.170.10 70 186 2.5E-43 T 16-09-2016 IPR013856 Peptidase M4 domain GO:0004222 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 PANTHER PTHR33794 8 356 3.8E-139 T 16-09-2016 Spa2297_RS10650 f9fa44b2417d02c39f66d5cfef19099e 356 Gene3D G3DSA:1.10.390.10 187 353 4.9E-50 T 16-09-2016 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 SMART SM00220 18 292 2.5E-33 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 Pfam PF00069 Protein kinase domain 19 289 3.0E-33 T 16-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 Gene3D G3DSA:3.30.200.20 17 148 2.5E-16 T 16-09-2016 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 Gene3D G3DSA:1.10.530.10 365 515 7.0E-11 T 16-09-2016 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 PANTHER PTHR24362 1 309 2.5E-50 T 16-09-2016 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 Gene3D G3DSA:1.10.510.10 149 289 2.6E-31 T 16-09-2016 Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 SUPERFAMILY SSF56112 12 289 2.16E-45 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 SUPERFAMILY SSF53955 364 518 2.81E-15 T 16-09-2016 IPR023346 Lysozyme-like domain Spa2297_RS20330 45d52b3fbe7ec2abbae0f931ed0690c2 521 PANTHER PTHR24362:SF0 1 309 2.5E-50 T 16-09-2016 Spa2297_RS20355 34ba6004b953119aec2162527fb3bce4 457 Pfam PF10901 Protein of unknown function (DUF2690) 354 445 5.1E-26 T 16-09-2016 IPR021224 Protein of unknown function DUF2690 Spa2297_RS20355 34ba6004b953119aec2162527fb3bce4 457 SMART SM00530 15 70 1.8E-4 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS20355 34ba6004b953119aec2162527fb3bce4 457 Pfam PF13560 Helix-turn-helix domain 12 67 9.4E-9 T 16-09-2016 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 Pfam PF00171 Aldehyde dehydrogenase family 22 495 4.9E-158 T 16-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 Gene3D G3DSA:3.40.309.10 270 470 1.5E-64 T 16-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 Gene3D G3DSA:3.40.605.10 17 269 1.0E-85 T 16-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 SUPERFAMILY SSF53720 15 499 1.13E-155 T 16-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 PANTHER PTHR11699:SF164 13 507 1.7E-276 T 16-09-2016 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 16-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 16-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 Spa2297_RS20365 aa99e9631a51b58055ec4505c8666a2a 509 PANTHER PTHR11699 13 507 1.7E-276 T 16-09-2016 Spa2297_RS31395 64d5e4b47fe4fe4c85daf60154c26aba 557 PANTHER PTHR30569 24 502 1.8E-77 T 16-09-2016 IPR030191 Cytosine permease GO:0015209|GO:0016021 Spa2297_RS28970 6b2434570ef9474c4c5d0647694a2ebc 221 PANTHER PTHR33393 5 219 5.8E-64 T 16-09-2016 Spa2297_RS28970 6b2434570ef9474c4c5d0647694a2ebc 221 PANTHER PTHR33393:SF4 5 219 5.8E-64 T 16-09-2016 Spa2297_RS28970 6b2434570ef9474c4c5d0647694a2ebc 221 Pfam PF04203 Sortase family 79 217 5.1E-16 T 16-09-2016 IPR005754 Sortase family Spa2297_RS28970 6b2434570ef9474c4c5d0647694a2ebc 221 Gene3D G3DSA:2.40.260.10 78 198 3.1E-7 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS28970 6b2434570ef9474c4c5d0647694a2ebc 221 SUPERFAMILY SSF63817 70 213 2.49E-15 T 16-09-2016 IPR023365 Sortase domain Spa2297_RS20460 b56c16eb44e53cfd8f5db0b2ab5d88af 325 PIRSF PIRSF035875 23 301 5.5E-26 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS20460 b56c16eb44e53cfd8f5db0b2ab5d88af 325 PANTHER PTHR30213:SF1 1 296 1.5E-69 T 16-09-2016 Spa2297_RS20460 b56c16eb44e53cfd8f5db0b2ab5d88af 325 Pfam PF03631 Virulence factor BrkB 44 292 3.3E-48 T 16-09-2016 IPR017039 Virulence factor BrkB Spa2297_RS20460 b56c16eb44e53cfd8f5db0b2ab5d88af 325 PANTHER PTHR30213 1 296 1.5E-69 T 16-09-2016 Spa2297_RS29785 646c968d988411821e02e907c9651053 227 Pfam PF14014 Protein of unknown function (DUF4230) 67 223 3.1E-31 T 16-09-2016 IPR025324 Protein of unknown function DUF4230 Spa2297_RS04460 801c7019c5663645085a670ac117a043 258 Pfam PF01774 UreD urease accessory protein 51 245 8.4E-24 T 16-09-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 Spa2297_RS04460 801c7019c5663645085a670ac117a043 258 Hamap MF_01384 Urease accessory protein UreD [ureD]. 12 256 19.77 T 16-09-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 Spa2297_RS26150 28ce1052038a78984a49ac3e29d5a9e0 214 PANTHER PTHR42305 1 211 1.2E-48 T 16-09-2016 Spa2297_RS06475 7273fe21155a00dc17bce6c6936f0bbe 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 3.1E-68 T 16-09-2016 IPR021441 Protein of unknown function DUF3090 Spa2297_RS06475 7273fe21155a00dc17bce6c6936f0bbe 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 1.4E-79 T 16-09-2016 IPR021441 Protein of unknown function DUF3090 Spa2297_RS31340 961efac07197d89e2e00bebb9f86d92d 108 SUPERFAMILY SSF52091 10 101 2.16E-15 T 16-09-2016 IPR002645 STAS domain Spa2297_RS31340 961efac07197d89e2e00bebb9f86d92d 108 Pfam PF13466 STAS domain 12 89 3.0E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS31340 961efac07197d89e2e00bebb9f86d92d 108 Gene3D G3DSA:3.30.750.24 9 103 4.4E-20 T 16-09-2016 IPR002645 STAS domain Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 PANTHER PTHR11773 1 961 0.0 T 16-09-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 SUPERFAMILY SSF53383 478 890 3.39E-98 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 SUPERFAMILY SSF53383 932 955 3.39E-98 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 953 0.0 T 16-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 SUPERFAMILY SSF53383 20 439 2.24E-104 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 959 25.655 T 16-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 Pfam PF02347 Glycine cleavage system P-protein 454 736 5.8E-12 T 16-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 Pfam PF02347 Glycine cleavage system P-protein 20 445 3.0E-179 T 16-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 PANTHER PTHR11773:SF1 1 961 0.0 T 16-09-2016 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 Gene3D G3DSA:3.40.640.10 94 310 4.9E-18 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS05045 f6116707a762fbf04d815813e48437ec 961 Gene3D G3DSA:3.40.640.10 505 741 3.5E-39 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PRINTS PR00069 Aldo-keto reductase signature 144 161 3.3E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PRINTS PR00069 Aldo-keto reductase signature 47 71 3.3E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PRINTS PR00069 Aldo-keto reductase signature 113 131 3.3E-6 T 16-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 SUPERFAMILY SSF51430 1 319 5.89E-107 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PANTHER PTHR11732 240 321 5.4E-141 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PANTHER PTHR11732 1 219 5.4E-141 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 Pfam PF00248 Aldo/keto reductase family 15 312 7.4E-79 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 Gene3D G3DSA:3.20.20.100 9 320 2.3E-107 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PANTHER PTHR11732:SF150 240 321 5.4E-141 T 16-09-2016 Spa2297_RS29875 86c919e8618ef57c1188d50736796977 322 PANTHER PTHR11732:SF150 1 219 5.4E-141 T 16-09-2016 Spa2297_RS19345 14251cc2ecc552efe3ed5b4c71971678 429 Gene3D G3DSA:3.90.550.10 94 318 6.8E-40 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS19345 14251cc2ecc552efe3ed5b4c71971678 429 PANTHER PTHR22916 39 230 1.5E-34 T 16-09-2016 Spa2297_RS19345 14251cc2ecc552efe3ed5b4c71971678 429 PANTHER PTHR22916 248 317 1.5E-34 T 16-09-2016 Spa2297_RS19345 14251cc2ecc552efe3ed5b4c71971678 429 SUPERFAMILY SSF53448 84 329 8.63E-46 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS19345 14251cc2ecc552efe3ed5b4c71971678 429 Pfam PF13641 Glycosyltransferase like family 2 92 322 6.3E-25 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 PANTHER PTHR30061:SF25 1 423 2.8E-176 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 Gene3D G3DSA:3.40.190.10 150 355 2.7E-44 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 Pfam PF13416 Bacterial extracellular solute-binding protein 54 363 1.0E-49 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 SUPERFAMILY SSF53850 19 417 2.08E-81 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 PANTHER PTHR30061 1 423 2.8E-176 T 16-09-2016 Spa2297_RS09325 a65473cbaf15593c38dc46d6df16c933 423 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 144 161 - T 16-09-2016 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 Spa2297_RS24495 9ce45fc0c9feb89b94e63e6b1816c66c 240 SUPERFAMILY SSF53213 9 239 3.79E-5 T 16-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Spa2297_RS26195 c96436593c7a80580c804e0bdba3ecb9 146 Gene3D G3DSA:3.30.530.20 4 131 1.0E-8 T 16-09-2016 IPR023393 START-like domain Spa2297_RS26195 c96436593c7a80580c804e0bdba3ecb9 146 SUPERFAMILY SSF55961 3 140 3.52E-14 T 16-09-2016 Spa2297_RS20640 88c12676710a092f4405a6196df72148 324 Gene3D G3DSA:3.90.550.10 2 203 5.2E-45 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS20640 88c12676710a092f4405a6196df72148 324 PANTHER PTHR22916:SF23 2 317 5.7E-59 T 16-09-2016 Spa2297_RS20640 88c12676710a092f4405a6196df72148 324 Pfam PF00535 Glycosyl transferase family 2 5 126 2.5E-32 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS20640 88c12676710a092f4405a6196df72148 324 PANTHER PTHR22916 2 317 5.7E-59 T 16-09-2016 Spa2297_RS20640 88c12676710a092f4405a6196df72148 324 SUPERFAMILY SSF53448 2 231 6.83E-48 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS33245 c393ab98974ce76088cf382b6248fdc8 214 PANTHER PTHR30472:SF16 54 214 1.3E-40 T 16-09-2016 Spa2297_RS33245 c393ab98974ce76088cf382b6248fdc8 214 Pfam PF01032 FecCD transport family 2 142 8.1E-30 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS33245 c393ab98974ce76088cf382b6248fdc8 214 SUPERFAMILY SSF81345 2 142 5.62E-25 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS33245 c393ab98974ce76088cf382b6248fdc8 214 Gene3D G3DSA:1.10.3470.10 1 144 6.6E-33 T 16-09-2016 IPR029022 ABC transporter, BtuC-like Spa2297_RS33245 c393ab98974ce76088cf382b6248fdc8 214 PANTHER PTHR30472 54 214 1.3E-40 T 16-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 Gene3D G3DSA:3.50.50.60 6 220 1.5E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 Gene3D G3DSA:3.50.50.60 321 489 2.4E-21 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 173 197 4.0E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 4.0E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 142 4.0E-5 T 16-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 SUPERFAMILY SSF51905 282 482 4.66E-22 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 PANTHER PTHR23023 8 493 8.3E-258 T 16-09-2016 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 Pfam PF00743 Flavin-binding monooxygenase-like 12 216 4.7E-18 T 16-09-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 SUPERFAMILY SSF51905 10 229 3.59E-59 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS13805 932a666743dc84f89db4bc6d43116f4a 511 PANTHER PTHR23023:SF132 8 493 8.3E-258 T 16-09-2016 Spa2297_RS17180 95d2a35820d96ce6e981bbc06523e348 117 Pfam PF06108 Protein of unknown function (DUF952) 6 102 3.5E-17 T 16-09-2016 IPR009297 Protein of unknown function DUF952 Spa2297_RS17180 95d2a35820d96ce6e981bbc06523e348 117 SUPERFAMILY SSF56399 1 112 4.03E-16 T 16-09-2016 Spa2297_RS27105 89c2e0a1deaa6cddd3bce36057c36c8f 75 PANTHER PTHR40137:SF1 1 74 1.4E-44 T 16-09-2016 Spa2297_RS27105 89c2e0a1deaa6cddd3bce36057c36c8f 75 PANTHER PTHR40137 1 74 1.4E-44 T 16-09-2016 Spa2297_RS27105 89c2e0a1deaa6cddd3bce36057c36c8f 75 Pfam PF05121 Gas vesicle protein K 2 72 3.7E-31 T 16-09-2016 IPR007805 Gas vesicle protein GvpK GO:0031412 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 SUPERFAMILY SSF53067 2 124 3.04E-24 T 16-09-2016 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 Gene3D G3DSA:3.30.420.150 123 305 1.3E-41 T 16-09-2016 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 Pfam PF02541 Ppx/GppA phosphatase family 17 303 1.4E-49 T 16-09-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 PANTHER PTHR30005 1 322 1.9E-83 T 16-09-2016 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 Gene3D G3DSA:3.30.420.40 1 122 1.0E-27 T 16-09-2016 Spa2297_RS29925 ab2b647642c50d2d889778830aab3bf5 336 SUPERFAMILY SSF53067 129 305 6.04E-32 T 16-09-2016 Spa2297_RS21955 f11f6b39d4ef243ca2bcdd6a610d1593 171 Gene3D G3DSA:3.90.79.10 43 166 2.7E-18 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS21955 f11f6b39d4ef243ca2bcdd6a610d1593 171 Pfam PF00293 NUDIX domain 43 154 3.8E-11 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS21955 f11f6b39d4ef243ca2bcdd6a610d1593 171 SUPERFAMILY SSF55811 17 166 6.91E-21 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06490 2a3bb3df786ac029ca38fa5d38e4ef75 262 Gene3D G3DSA:1.20.1260.10 48 163 1.6E-4 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS06490 2a3bb3df786ac029ca38fa5d38e4ef75 262 SUPERFAMILY SSF47240 15 171 4.27E-6 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS17920 bc7368d4c0a1e1ca18727746080d1e1b 274 Gene3D G3DSA:1.10.3290.10 151 251 2.5E-5 T 16-09-2016 IPR003812 Fido domain Spa2297_RS17920 bc7368d4c0a1e1ca18727746080d1e1b 274 SUPERFAMILY SSF140931 109 251 4.84E-6 T 16-09-2016 IPR003812 Fido domain Spa2297_RS18215 052ad5cc238d7c11f32333f0e75ad485 599 PANTHER PTHR34697 1 594 8.8E-164 T 16-09-2016 Spa2297_RS18215 052ad5cc238d7c11f32333f0e75ad485 599 PANTHER PTHR34697:SF2 1 594 8.8E-164 T 16-09-2016 Spa2297_RS18215 052ad5cc238d7c11f32333f0e75ad485 599 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 245 551 6.7E-107 T 16-09-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal Spa2297_RS18215 052ad5cc238d7c11f32333f0e75ad485 599 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 22 221 9.4E-13 T 16-09-2016 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 PANTHER PTHR30345 1 155 1.0E-61 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 Pfam PF02502 Ribose/Galactose Isomerase 3 142 2.8E-45 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.0E-52 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 Gene3D G3DSA:3.40.1400.10 1 149 2.0E-54 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 2.3E-74 T 16-09-2016 IPR011860 Ribose 5-phosphate isomerase GO:0004751 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 SUPERFAMILY SSF89623 1 151 4.19E-52 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS11125 39e7feee83dd656f9b86bc30c27cb7f8 161 PIRSF PIRSF005384 1 149 5.8E-50 T 16-09-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 Spa2297_RS31335 eb69a6a7dcd1ade2ba845548dd8df12e 118 SUPERFAMILY SSF55874 31 118 1.08E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS31870 0254feb3811c2f730af1d77c3a48d35e 441 PANTHER PTHR21021 110 413 6.1E-38 T 16-09-2016 Spa2297_RS31870 0254feb3811c2f730af1d77c3a48d35e 441 PANTHER PTHR21021:SF22 110 413 6.1E-38 T 16-09-2016 Spa2297_RS31870 0254feb3811c2f730af1d77c3a48d35e 441 SUPERFAMILY SSF81606 201 402 1.7E-11 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31870 0254feb3811c2f730af1d77c3a48d35e 441 SMART SM00331 187 404 1.5E-18 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS31870 0254feb3811c2f730af1d77c3a48d35e 441 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 216 404 3.0E-35 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS12310 8e0190386782f3072849468935d121b9 213 Gene3D G3DSA:3.40.50.300 19 124 1.3E-10 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12310 8e0190386782f3072849468935d121b9 213 PANTHER PTHR11711 23 212 2.4E-44 T 16-09-2016 Spa2297_RS12310 8e0190386782f3072849468935d121b9 213 SUPERFAMILY SSF52540 22 193 6.68E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS12310 8e0190386782f3072849468935d121b9 213 PANTHER PTHR11711:SF117 23 212 2.4E-44 T 16-09-2016 Spa2297_RS12310 8e0190386782f3072849468935d121b9 213 Pfam PF03029 Conserved hypothetical ATP binding protein 26 193 2.7E-18 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS00085 3b87636cbc7bc8c1e575c74830c3eacf 466 SMART SM00530 23 79 0.0014 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS00085 3b87636cbc7bc8c1e575c74830c3eacf 466 Gene3D G3DSA:1.10.260.40 18 80 2.5E-5 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS00085 3b87636cbc7bc8c1e575c74830c3eacf 466 Pfam PF13560 Helix-turn-helix domain 19 82 6.4E-11 T 16-09-2016 Spa2297_RS00085 3b87636cbc7bc8c1e575c74830c3eacf 466 SUPERFAMILY SSF47413 23 90 1.93E-6 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS02850 cb2c937eae4818d1ee9e1c627fdaf37b 92 SUPERFAMILY SSF47336 3 80 1.44E-13 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02850 cb2c937eae4818d1ee9e1c627fdaf37b 92 Gene3D G3DSA:1.10.1200.10 2 76 1.7E-16 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS02850 cb2c937eae4818d1ee9e1c627fdaf37b 92 Pfam PF00550 Phosphopantetheine attachment site 8 73 1.4E-9 T 16-09-2016 IPR009081 Phosphopantetheine binding ACP domain Spa2297_RS29920 ebea9053096f45222adfea7b207ebc63 343 Gene3D G3DSA:1.20.910.10 101 323 4.1E-57 T 16-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 Spa2297_RS29920 ebea9053096f45222adfea7b207ebc63 343 SMART SM01236 163 268 4.9E-35 T 16-09-2016 Spa2297_RS29920 ebea9053096f45222adfea7b207ebc63 343 Pfam PF14518 Iron-containing redox enzyme 131 302 8.0E-43 T 16-09-2016 IPR028201 PqqC-like protein Spa2297_RS29920 ebea9053096f45222adfea7b207ebc63 343 SUPERFAMILY SSF48613 127 294 2.22E-9 T 16-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 Spa2297_RS30070 a6ed4c5dc9a8baa7e76b800ebe0b66a7 292 SUPERFAMILY SSF56059 106 262 6.03E-7 T 16-09-2016 Spa2297_RS25315 5a1421da03889250859754e1a734189f 540 PANTHER PTHR24045 41 382 1.0E-28 T 16-09-2016 Spa2297_RS25315 5a1421da03889250859754e1a734189f 540 Pfam PF11380 Stealth protein CR2, conserved region 2 290 371 3.1E-8 T 16-09-2016 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 KEGG: 00563+2.7.-.- Spa2297_RS28300 bf8c2efc62a9a6fff4aa327d7dee5972 144 Gene3D G3DSA:3.30.450.30 8 128 1.8E-19 T 16-09-2016 Spa2297_RS28300 bf8c2efc62a9a6fff4aa327d7dee5972 144 PANTHER PTHR36222 2 143 2.3E-51 T 16-09-2016 Spa2297_RS28300 bf8c2efc62a9a6fff4aa327d7dee5972 144 SUPERFAMILY SSF103196 8 133 3.4E-24 T 16-09-2016 Spa2297_RS28300 bf8c2efc62a9a6fff4aa327d7dee5972 144 SMART SM00960 14 104 1.5E-22 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS28300 bf8c2efc62a9a6fff4aa327d7dee5972 144 Pfam PF03259 Roadblock/LC7 domain 13 104 1.7E-23 T 16-09-2016 IPR004942 Roadblock/LAMTOR2 domain Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 Gene3D G3DSA:3.30.70.100 219 308 2.6E-9 T 16-09-2016 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 Pfam PF00924 Mechanosensitive ion channel 111 310 9.5E-40 T 16-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 SUPERFAMILY SSF82861 93 151 4.97E-13 T 16-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 SUPERFAMILY SSF82689 216 320 1.57E-21 T 16-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 Gene3D G3DSA:2.30.30.60 168 211 3.6E-9 T 16-09-2016 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 SUPERFAMILY SSF50182 153 210 6.87E-10 T 16-09-2016 IPR010920 LSM domain Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 PANTHER PTHR30460 94 324 1.5E-100 T 16-09-2016 Spa2297_RS29515 e233847bc8c3b98674ae61789dbd2c86 333 PANTHER PTHR30460 16 73 1.5E-100 T 16-09-2016 Spa2297_RS18790 46460798f8c9b7ac1d63dfc752541512 420 Gene3D G3DSA:3.20.20.370 72 379 5.8E-11 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS18790 46460798f8c9b7ac1d63dfc752541512 420 SUPERFAMILY SSF88713 147 379 4.45E-27 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS18790 46460798f8c9b7ac1d63dfc752541512 420 SUPERFAMILY SSF88713 71 117 4.45E-27 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 Pfam PF00464 Serine hydroxymethyltransferase 23 391 1.2E-130 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 PANTHER PTHR11680 21 419 8.9E-172 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 20 420 45.148 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 PIRSF PIRSF000412 14 415 3.8E-140 T 16-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 Gene3D G3DSA:3.40.640.10 50 296 8.6E-95 T 16-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 Gene3D G3DSA:3.90.1150.10 297 419 8.2E-31 T 16-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 SUPERFAMILY SSF53383 18 420 2.64E-145 T 16-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase Spa2297_RS22655 4d9268788ee706d28aa57bcfd24faf3a 421 PANTHER PTHR11680:SF0 21 419 8.9E-172 T 16-09-2016 Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 Gene3D G3DSA:3.10.180.10 38 103 6.1E-14 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 Gene3D G3DSA:3.10.180.10 2 28 4.3E-5 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 SUPERFAMILY SSF54593 3 103 1.75E-16 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 PANTHER PTHR36503 1 115 2.2E-38 T 16-09-2016 Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 Gene3D G3DSA:3.10.180.10 120 186 3.2E-5 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS17200 be1bac360b0895d879b73f0941d08862 204 PANTHER PTHR36503:SF1 1 115 2.2E-38 T 16-09-2016 Spa2297_RS00055 c7a1969db4efc20e061b3e0e98d99d1e 173 SUPERFAMILY SSF51182 17 156 5.03E-25 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS00055 c7a1969db4efc20e061b3e0e98d99d1e 173 PANTHER PTHR36440:SF1 1 169 5.2E-23 T 16-09-2016 Spa2297_RS00055 c7a1969db4efc20e061b3e0e98d99d1e 173 Pfam PF07883 Cupin domain 54 119 2.3E-15 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS00055 c7a1969db4efc20e061b3e0e98d99d1e 173 PANTHER PTHR36440 1 169 5.2E-23 T 16-09-2016 Spa2297_RS00055 c7a1969db4efc20e061b3e0e98d99d1e 173 Gene3D G3DSA:2.60.120.10 31 169 5.2E-31 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS10205 a3eae4a827e7abacd3c894166e98fb94 254 PANTHER PTHR30188:SF4 2 253 1.1E-93 T 16-09-2016 Spa2297_RS10205 a3eae4a827e7abacd3c894166e98fb94 254 Pfam PF02405 Permease MlaE 33 243 5.3E-67 T 16-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 Spa2297_RS10205 a3eae4a827e7abacd3c894166e98fb94 254 PANTHER PTHR30188 2 253 1.1E-93 T 16-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 Spa2297_RS00475 8865aa37f3cca4200f22595fbccbe869 373 SUPERFAMILY SSF54001 257 367 4.9E-34 T 16-09-2016 Spa2297_RS00475 8865aa37f3cca4200f22595fbccbe869 373 Gene3D G3DSA:3.90.1720.10 258 361 1.3E-35 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS00475 8865aa37f3cca4200f22595fbccbe869 373 Pfam PF00877 NlpC/P60 family 272 355 8.5E-20 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS00475 8865aa37f3cca4200f22595fbccbe869 373 PANTHER PTHR21666 257 355 3.1E-28 T 16-09-2016 Spa2297_RS00565 29ffbadd49c27cccb712579edd814013 196 Pfam PF06197 Protein of unknown function (DUF998) 15 186 5.9E-32 T 16-09-2016 IPR009339 Protein of unknown function DUF998 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 66 444 1.0E-89 T 16-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 SUPERFAMILY SSF56317 220 478 9.03E-42 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 PANTHER PTHR38686 3 502 9.9E-89 T 16-09-2016 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 Gene3D G3DSA:3.60.110.10 215 477 1.3E-32 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 11 483 16.417 T 16-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 Spa2297_RS04885 d7ece2ab2fe9f32c707ee66c30094912 524 Pfam PF00795 Carbon-nitrogen hydrolase 221 456 2.8E-22 T 16-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 Spa2297_RS03980 d48c43a6da8be13d673c486c799d1084 191 PANTHER PTHR39624 1 190 1.9E-94 T 16-09-2016 Spa2297_RS03980 d48c43a6da8be13d673c486c799d1084 191 SUPERFAMILY SSF82784 61 177 4.06E-25 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS03980 d48c43a6da8be13d673c486c799d1084 191 Gene3D G3DSA:3.30.300.20 61 177 6.8E-24 T 16-09-2016 IPR015946 K homology domain-like, alpha/beta Spa2297_RS03980 d48c43a6da8be13d673c486c799d1084 191 PANTHER PTHR39624:SF1 1 190 1.9E-94 T 16-09-2016 Spa2297_RS03980 d48c43a6da8be13d673c486c799d1084 191 Pfam PF02566 OsmC-like protein 81 174 1.5E-15 T 16-09-2016 IPR003718 OsmC/Ohr family Spa2297_RS16165 66b6de06aa4591f254be1b830dfbbba3 477 PANTHER PTHR21021 235 477 1.2E-33 T 16-09-2016 Spa2297_RS16165 66b6de06aa4591f254be1b830dfbbba3 477 PANTHER PTHR21021 156 173 1.2E-33 T 16-09-2016 Spa2297_RS16165 66b6de06aa4591f254be1b830dfbbba3 477 SMART SM00331 257 476 6.7E-17 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS16165 66b6de06aa4591f254be1b830dfbbba3 477 Gene3D G3DSA:3.30.450.40 67 193 0.001 T 16-09-2016 IPR029016 GAF domain-like Spa2297_RS16165 66b6de06aa4591f254be1b830dfbbba3 477 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 284 476 2.6E-37 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS25165 2869e93351e13cb5d5dd81843aa057cb 275 PANTHER PTHR10992 4 273 3.5E-32 T 16-09-2016 Spa2297_RS25165 2869e93351e13cb5d5dd81843aa057cb 275 SUPERFAMILY SSF53474 4 273 1.05E-40 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS25165 2869e93351e13cb5d5dd81843aa057cb 275 Gene3D G3DSA:3.40.50.1820 5 272 2.2E-41 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS04395 ca96a2d6fc0a5d6e2b92961740fc0699 316 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 38 280 2.4E-80 T 16-09-2016 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related Spa2297_RS09255 46b4eb61badc5a29d804ee45c008c47a 504 PANTHER PTHR32208:SF28 293 498 8.7E-56 T 16-09-2016 Spa2297_RS09255 46b4eb61badc5a29d804ee45c008c47a 504 Pfam PF09362 Domain of unknown function (DUF1996) 252 483 1.4E-29 T 16-09-2016 IPR018535 Domain of unknown function DUF1996 Spa2297_RS09255 46b4eb61badc5a29d804ee45c008c47a 504 PANTHER PTHR32208 293 498 8.7E-56 T 16-09-2016 Spa2297_RS01975 6443962d88ecf6e231fe02d9e6f5e42f 110 Pfam PF03861 ANTAR domain 23 75 4.8E-14 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS01975 6443962d88ecf6e231fe02d9e6f5e42f 110 Gene3D G3DSA:1.10.10.10 23 77 7.9E-9 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS01975 6443962d88ecf6e231fe02d9e6f5e42f 110 SMART SM01012 20 75 2.2E-13 T 16-09-2016 IPR005561 ANTAR domain GO:0003723 Spa2297_RS01975 6443962d88ecf6e231fe02d9e6f5e42f 110 PIRSF PIRSF010636 8 109 4.7E-41 T 16-09-2016 IPR024189 ANTAR transcription anti-termination regulator Spa2297_RS15645 1b2d87fdf0d6f1502487db2bbedcbe8c 314 Gene3D G3DSA:3.20.20.100 5 312 3.4E-82 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS15645 1b2d87fdf0d6f1502487db2bbedcbe8c 314 SUPERFAMILY SSF51430 5 312 7.07E-84 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS15645 1b2d87fdf0d6f1502487db2bbedcbe8c 314 PANTHER PTHR11732 2 312 1.4E-180 T 16-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta Spa2297_RS15645 1b2d87fdf0d6f1502487db2bbedcbe8c 314 Pfam PF00248 Aldo/keto reductase family 16 312 5.8E-65 T 16-09-2016 IPR023210 NADP-dependent oxidoreductase domain Spa2297_RS15645 1b2d87fdf0d6f1502487db2bbedcbe8c 314 PANTHER PTHR11732:SF132 2 312 1.4E-180 T 16-09-2016 Spa2297_RS04745 700823918d8fbcb06a6a78caacd8a11f 67 Gene3D G3DSA:3.40.50.720 1 64 3.8E-4 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS04850 b916c705c838ff863473b5c846d0f960 281 Gene3D G3DSA:3.40.50.150 11 266 2.1E-66 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04850 b916c705c838ff863473b5c846d0f960 281 SUPERFAMILY SSF53335 13 236 3.99E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS04850 b916c705c838ff863473b5c846d0f960 281 PANTHER PTHR12176:SF22 17 247 1.5E-132 T 16-09-2016 Spa2297_RS04850 b916c705c838ff863473b5c846d0f960 281 PANTHER PTHR12176 17 247 1.5E-132 T 16-09-2016 Spa2297_RS14785 3d55fdbbc64429be42f60fb651f84b53 87 Pfam PF04149 Domain of unknown function (DUF397) 8 26 4.6E-6 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS14785 3d55fdbbc64429be42f60fb651f84b53 87 Pfam PF04149 Domain of unknown function (DUF397) 26 80 4.6E-22 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS28815 b3c5cc19a06282157911510da568b029 114 Gene3D G3DSA:3.40.630.30 3 90 9.8E-19 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28815 b3c5cc19a06282157911510da568b029 114 SUPERFAMILY SSF55729 4 94 7.8E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28815 b3c5cc19a06282157911510da568b029 114 Pfam PF14542 GCN5-related N-acetyl-transferase 18 90 1.3E-17 T 16-09-2016 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase Spa2297_RS28815 b3c5cc19a06282157911510da568b029 114 PANTHER PTHR31435 3 100 1.4E-20 T 16-09-2016 Spa2297_RS08170 cacf4b9c84f93c23938bd42576f696cb 608 PANTHER PTHR30482 253 606 3.3E-134 T 16-09-2016 Spa2297_RS08170 cacf4b9c84f93c23938bd42576f696cb 608 PANTHER PTHR30482:SF10 253 606 3.3E-134 T 16-09-2016 Spa2297_RS08170 cacf4b9c84f93c23938bd42576f696cb 608 Pfam PF02653 Branched-chain amino acid transport system / permease component 290 576 3.2E-41 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS05960 cd2d9b5e5a0c1f4ffb9e54ee22d57cf9 212 PANTHER PTHR13256 6 211 9.8E-65 T 16-09-2016 Spa2297_RS05960 cd2d9b5e5a0c1f4ffb9e54ee22d57cf9 212 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 1.3E-27 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS05960 cd2d9b5e5a0c1f4ffb9e54ee22d57cf9 212 PANTHER PTHR13256:SF21 6 211 9.8E-65 T 16-09-2016 Spa2297_RS05960 cd2d9b5e5a0c1f4ffb9e54ee22d57cf9 212 SUPERFAMILY SSF55729 6 175 1.16E-36 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS05960 cd2d9b5e5a0c1f4ffb9e54ee22d57cf9 212 Gene3D G3DSA:3.40.630.30 8 193 1.1E-47 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS22480 7813ba0a35314eb8c6ac03863ba035d3 398 Gene3D G3DSA:3.30.70.900 30 119 1.2E-14 T 16-09-2016 Spa2297_RS22480 7813ba0a35314eb8c6ac03863ba035d3 398 SUPERFAMILY SSF54909 29 119 9.39E-19 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS22480 7813ba0a35314eb8c6ac03863ba035d3 398 Pfam PF04486 SchA/CurD like domain 147 258 3.0E-46 T 16-09-2016 IPR007575 SchA/CurD-like domain Spa2297_RS22480 7813ba0a35314eb8c6ac03863ba035d3 398 Pfam PF03992 Antibiotic biosynthesis monooxygenase 29 103 5.2E-15 T 16-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain Spa2297_RS13525 30f49c2035202dcb03c6aaa1d58c1d22 871 Pfam PF14435 SUKH-4 immunity protein 689 865 4.9E-40 T 16-09-2016 IPR025851 SUKH-4 immunity protein Spa2297_RS13525 30f49c2035202dcb03c6aaa1d58c1d22 871 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 553 652 8.9E-32 T 16-09-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like Spa2297_RS25650 8464b4a35a40a98851d7b811cb6ba679 402 Gene3D G3DSA:3.30.470.20 101 393 9.0E-35 T 16-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 Spa2297_RS25650 8464b4a35a40a98851d7b811cb6ba679 402 Pfam PF13535 ATP-grasp domain 142 283 7.5E-15 T 16-09-2016 Spa2297_RS25650 8464b4a35a40a98851d7b811cb6ba679 402 SUPERFAMILY SSF56059 102 314 1.27E-37 T 16-09-2016 Spa2297_RS25650 8464b4a35a40a98851d7b811cb6ba679 402 PANTHER PTHR23132 83 286 5.9E-22 T 16-09-2016 Spa2297_RS22800 2930e37631192b8e0243de01629a631d 256 Pfam PF12679 ABC-2 family transporter protein 67 255 8.8E-8 T 16-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 16-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 PANTHER PTHR11941:SF28 2 260 9.5E-67 T 16-09-2016 Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 SUPERFAMILY SSF52096 14 259 2.9E-57 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 PANTHER PTHR11941 2 260 9.5E-67 T 16-09-2016 Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 Gene3D G3DSA:3.90.226.10 15 248 6.6E-55 T 16-09-2016 IPR029045 ClpP/crotonase-like domain Spa2297_RS07340 74504bba68e15620c0aa7f684b71dd7f 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 253 4.5E-34 T 16-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 Pfam PF01494 FAD binding domain 2 334 2.6E-92 T 16-09-2016 IPR002938 FAD-binding domain GO:0071949 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 Gene3D G3DSA:3.50.50.60 2 169 1.2E-57 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 Gene3D G3DSA:3.50.50.60 257 341 1.2E-57 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PANTHER PTHR13789 2 416 1.3E-138 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PANTHER PTHR13789:SF90 2 416 1.3E-138 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 SUPERFAMILY SSF51905 256 353 2.99E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 SUPERFAMILY SSF51905 2 164 2.99E-65 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 4.8E-47 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 4.8E-47 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 4.8E-47 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 4.8E-47 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 4.8E-47 T 16-09-2016 Spa2297_RS00880 bb258f27f583e4ebf26a0bdc19b31dd1 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 4.8E-47 T 16-09-2016 Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 Gene3D G3DSA:3.90.950.10 7 194 2.2E-60 T 16-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 Hamap MF_00528 Septum formation protein Maf [maf]. 8 197 28.206 T 16-09-2016 IPR003697 Maf-like protein GO:0005737 Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 Pfam PF02545 Maf-like protein 8 192 1.7E-46 T 16-09-2016 IPR003697 Maf-like protein GO:0005737 Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 190 2.0E-45 T 16-09-2016 IPR003697 Maf-like protein GO:0005737 Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 PIRSF PIRSF006305 1 199 1.8E-44 T 16-09-2016 IPR003697 Maf-like protein GO:0005737 Spa2297_RS20845 691407c322ce208443a6d4572fe79fd1 206 SUPERFAMILY SSF52972 7 192 4.58E-54 T 16-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like Spa2297_RS27350 3d690d097557dd7ae212f20ed5999b8b 339 PANTHER PTHR32196 6 335 1.4E-159 T 16-09-2016 Spa2297_RS27350 3d690d097557dd7ae212f20ed5999b8b 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 329 3.3E-44 T 16-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 Spa2297_RS27350 3d690d097557dd7ae212f20ed5999b8b 339 PANTHER PTHR32196:SF34 6 335 1.4E-159 T 16-09-2016 Spa2297_RS24390 2393b6ec186b6e511f68abc4bbf10056 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 2.3E-30 T 16-09-2016 IPR021408 Protein of unknown function DUF3046 Spa2297_RS13365 f0b1e7e0f36e4305ea6c721bb7c9ad10 340 SUPERFAMILY SSF52266 71 269 7.94E-27 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS13365 f0b1e7e0f36e4305ea6c721bb7c9ad10 340 Gene3D G3DSA:3.40.50.1110 71 267 1.2E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS13365 f0b1e7e0f36e4305ea6c721bb7c9ad10 340 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 77 255 1.4E-20 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS23685 2fbf2258047cc817d5a0b54c47c836e9 406 Gene3D G3DSA:2.115.10.10 153 372 5.4E-34 T 16-09-2016 IPR023294 Tachylectin 2 Spa2297_RS23685 2fbf2258047cc817d5a0b54c47c836e9 406 Pfam PF03995 Peptidase inhibitor family I36 31 93 1.5E-16 T 16-09-2016 Spa2297_RS23685 2fbf2258047cc817d5a0b54c47c836e9 406 SUPERFAMILY SSF69318 137 391 1.5E-32 T 16-09-2016 Spa2297_RS23685 2fbf2258047cc817d5a0b54c47c836e9 406 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 195 257 4.8E-7 T 16-09-2016 Spa2297_RS23685 2fbf2258047cc817d5a0b54c47c836e9 406 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 299 360 2.4E-9 T 16-09-2016 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 SUPERFAMILY SSF54768 33 99 1.46E-21 T 16-09-2016 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 Gene3D G3DSA:3.30.230.10 101 181 1.8E-32 T 16-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 Gene3D G3DSA:3.30.160.20 34 95 2.1E-28 T 16-09-2016 IPR014720 Double-stranded RNA-binding domain Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 32 186 1.2E-67 T 16-09-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 16-09-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 5.1E-29 T 16-09-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 SUPERFAMILY SSF54211 102 181 9.1E-25 T 16-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 5.2E-27 T 16-09-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 186 34.523 T 16-09-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19880 bad3fc24e96fd9a0959b26df6052991a 201 PANTHER PTHR13718 36 187 3.4E-69 T 16-09-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 PANTHER PTHR12001:SF47 20 336 7.3E-98 T 16-09-2016 Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 SUPERFAMILY SSF48576 20 334 8.8E-79 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 PANTHER PTHR12001 20 336 7.3E-98 T 16-09-2016 IPR017446 Polyprenyl synthetase-related Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 Pfam PF00348 Polyprenyl synthetase 42 284 3.1E-56 T 16-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 Spa2297_RS19365 e5a9cf9133aad07263c1fab16577e9de 336 Gene3D G3DSA:1.10.600.10 17 334 4.3E-86 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS00985 8d60b20d595f8f85e546a0ab985ac9c3 135 Pfam PF01042 Endoribonuclease L-PSP 14 127 1.6E-25 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS00985 8d60b20d595f8f85e546a0ab985ac9c3 135 Gene3D G3DSA:3.30.1330.40 7 129 1.5E-35 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS00985 8d60b20d595f8f85e546a0ab985ac9c3 135 SUPERFAMILY SSF55298 8 129 3.3E-34 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS00985 8d60b20d595f8f85e546a0ab985ac9c3 135 PANTHER PTHR11803 7 129 2.1E-39 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS04495 b4a8a88a8d8addaef4588404b92e6fc3 125 Gene3D G3DSA:3.10.180.10 5 122 5.6E-22 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS04495 b4a8a88a8d8addaef4588404b92e6fc3 125 SUPERFAMILY SSF54593 1 123 3.99E-14 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS04495 b4a8a88a8d8addaef4588404b92e6fc3 125 PANTHER PTHR33993 2 125 2.3E-13 T 16-09-2016 Spa2297_RS04495 b4a8a88a8d8addaef4588404b92e6fc3 125 PANTHER PTHR33993:SF3 2 125 2.3E-13 T 16-09-2016 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 Pfam PF00962 Adenosine/AMP deaminase 10 334 5.2E-94 T 16-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 281 287 - T 16-09-2016 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: REACT_1698 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 PANTHER PTHR11409 7 340 3.8E-170 T 16-09-2016 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 SUPERFAMILY SSF51556 8 340 2.12E-69 T 16-09-2016 IPR032466 Metal-dependent hydrolase Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 336 3.7E-114 T 16-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 PANTHER PTHR11409:SF36 7 340 3.8E-170 T 16-09-2016 Spa2297_RS19590 988e647195ac6279c1dbeb46c8b98c25 343 Gene3D G3DSA:3.20.20.140 8 340 3.2E-83 T 16-09-2016 Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 PIRSF PIRSF015244 1 424 5.7E-214 T 16-09-2016 IPR012353 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 SUPERFAMILY SSF53187 83 343 5.91E-36 T 16-09-2016 Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 Pfam PF09940 Domain of unknown function (DUF2172) 59 150 6.3E-39 T 16-09-2016 IPR032610 Domain of unknown function DUF2172 Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 Pfam PF16221 winged helix-turn-helix 348 423 1.4E-31 T 16-09-2016 IPR032622 UCP01524, winged helix-turn-helix domain Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 Pfam PF16254 Domain of unknown function (DUF4910) 9 346 1.5E-114 T 16-09-2016 IPR032589 Domain of unknown function DUF4910 Spa2297_RS31740 6cad6d8d9700336b866eee61d05188fd 424 Gene3D G3DSA:3.40.630.10 183 344 1.6E-10 T 16-09-2016 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PANTHER PTHR11786 5 275 1.7E-58 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 Gene3D G3DSA:3.30.2140.10 1 86 2.1E-54 T 16-09-2016 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 Gene3D G3DSA:3.30.2140.10 200 280 2.1E-54 T 16-09-2016 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 SUPERFAMILY SSF54001 2 278 1.53E-67 T 16-09-2016 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PRINTS PR01543 Arylamine N-acetyltransferase signature 22 45 5.7E-15 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PRINTS PR01543 Arylamine N-acetyltransferase signature 188 210 5.7E-15 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PRINTS PR01543 Arylamine N-acetyltransferase signature 46 69 5.7E-15 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PRINTS PR01543 Arylamine N-acetyltransferase signature 265 278 5.7E-15 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 PRINTS PR01543 Arylamine N-acetyltransferase signature 70 92 5.7E-15 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS10820 80b166b64993aa5e9016dc53b587a3f6 291 Pfam PF00797 N-acetyltransferase 24 274 1.0E-66 T 16-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 SUPERFAMILY SSF52540 9 283 4.65E-44 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 Gene3D G3DSA:1.10.8.300 201 307 1.1E-36 T 16-09-2016 Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 Gene3D G3DSA:3.40.50.300 25 185 7.0E-42 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 PIRSF PIRSF002849 2 313 6.4E-130 T 16-09-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 168 5.4E-65 T 16-09-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spa2297_RS08575 14a4692769aaf4eb50fcbd1dec32e84f 337 PANTHER PTHR11603 4 311 1.7E-131 T 16-09-2016 Spa2297_RS23635 40bd94b90c4df20a621a4b1850d0d335 217 Pfam PF02620 Uncharacterized ACR, COG1399 69 189 2.2E-32 T 16-09-2016 IPR003772 Protein of unknown function DUF177 Spa2297_RS23635 40bd94b90c4df20a621a4b1850d0d335 217 PANTHER PTHR34374 1 201 5.9E-61 T 16-09-2016 Spa2297_RS31880 370cee245747c117cfc9a53315b484f8 251 SUPERFAMILY SSF51366 11 219 1.93E-6 T 16-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 Spa2297_RS31880 370cee245747c117cfc9a53315b484f8 251 PIRSF PIRSF015957 1 245 8.8E-117 T 16-09-2016 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5423|MetaCyc: PWY-7410 Spa2297_RS31880 370cee245747c117cfc9a53315b484f8 251 Pfam PF04476 Putative methanogenic enzyme for methanofuran 3 232 4.1E-80 T 16-09-2016 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5423|MetaCyc: PWY-7410 Spa2297_RS06815 049a7ea1cd9427cd476b0b3b932e0649 209 Pfam PF08241 Methyltransferase domain 59 152 2.1E-22 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS06815 049a7ea1cd9427cd476b0b3b932e0649 209 SUPERFAMILY SSF53335 19 163 6.08E-38 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS06815 049a7ea1cd9427cd476b0b3b932e0649 209 Gene3D G3DSA:3.40.50.150 39 160 9.9E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS06815 049a7ea1cd9427cd476b0b3b932e0649 209 PANTHER PTHR10108 19 159 1.2E-31 T 16-09-2016 Spa2297_RS06815 049a7ea1cd9427cd476b0b3b932e0649 209 PANTHER PTHR10108:SF721 19 159 1.2E-31 T 16-09-2016 Spa2297_RS25860 b467416f1dfb162b68456481c6cf26ef 297 Pfam PF12698 ABC-2 family transporter protein 73 266 2.8E-20 T 16-09-2016 Spa2297_RS25860 b467416f1dfb162b68456481c6cf26ef 297 PANTHER PTHR30294 29 283 7.7E-26 T 16-09-2016 Spa2297_RS25860 b467416f1dfb162b68456481c6cf26ef 297 PIRSF PIRSF006648 1 277 2.6E-21 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS30560 e9d8ecad524e89103c3729216d5f1d0c 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 413 3.4E-8 T 16-09-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Spa2297_RS31575 174d6fe24cb2bc1845085d8bb1d3bcf2 439 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 16-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS31575 174d6fe24cb2bc1845085d8bb1d3bcf2 439 PANTHER PTHR11119 1 420 4.0E-67 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS31575 174d6fe24cb2bc1845085d8bb1d3bcf2 439 Pfam PF00860 Permease family 10 387 2.5E-59 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 SMART SM00530 10 82 4.1E-7 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 PANTHER PTHR35010 5 281 1.3E-51 T 16-09-2016 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 PANTHER PTHR35010:SF2 5 281 1.3E-51 T 16-09-2016 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 SUPERFAMILY SSF47413 30 78 1.48E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 Gene3D G3DSA:1.10.260.40 3 78 8.9E-20 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS29290 a38f8759d51464e352f0a4655f151e91 285 Pfam PF13560 Helix-turn-helix domain 6 83 4.0E-13 T 16-09-2016 Spa2297_RS22155 9e41266b6712fc236004dc7e09f538b9 496 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 40 329 1.2E-74 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS22155 9e41266b6712fc236004dc7e09f538b9 496 Gene3D G3DSA:3.20.20.300 19 335 5.2E-93 T 16-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spa2297_RS22155 9e41266b6712fc236004dc7e09f538b9 496 PANTHER PTHR30480 8 359 2.2E-119 T 16-09-2016 Spa2297_RS22155 9e41266b6712fc236004dc7e09f538b9 496 PANTHER PTHR30480:SF2 8 359 2.2E-119 T 16-09-2016 Spa2297_RS22155 9e41266b6712fc236004dc7e09f538b9 496 SUPERFAMILY SSF51445 20 333 2.0E-79 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 1.1E-46 T 16-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 182 3.0E-72 T 16-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 176 2.4E-55 T 16-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 PANTHER PTHR21047 7 179 2.7E-56 T 16-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 Gene3D G3DSA:2.60.120.10 8 179 7.1E-62 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS31720 f1fdbc5af632214eaea9373327bbb14c 183 SUPERFAMILY SSF51182 8 178 2.39E-57 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 SMART SM00062 21 251 4.1E-38 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 SUPERFAMILY SSF53850 19 248 9.19E-44 T 16-09-2016 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 PANTHER PTHR18966 23 245 9.6E-77 T 16-09-2016 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 247 3.1E-43 T 16-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 Gene3D G3DSA:3.40.190.10 99 192 1.4E-11 T 16-09-2016 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 Gene3D G3DSA:3.40.190.10 210 247 8.3E-25 T 16-09-2016 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 Gene3D G3DSA:3.40.190.10 20 98 8.3E-25 T 16-09-2016 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 11 263 1.6E-82 T 16-09-2016 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 Spa2297_RS12075 7888b7a46fd85811bf73ac47a45fa397 265 PANTHER PTHR18966:SF216 23 245 9.6E-77 T 16-09-2016 Spa2297_RS03935 810f034f9b94d1ca8737ca3703df4cda 146 SUPERFAMILY SSF50475 9 132 8.29E-21 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS03935 810f034f9b94d1ca8737ca3703df4cda 146 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 131 2.7E-25 T 16-09-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Spa2297_RS03935 810f034f9b94d1ca8737ca3703df4cda 146 Gene3D G3DSA:2.30.110.10 3 137 2.0E-38 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS31290 68d9c7d0c8d82da93d6fd0a30820fa01 239 PANTHER PTHR41293 1 237 7.6E-115 T 16-09-2016 Spa2297_RS31290 68d9c7d0c8d82da93d6fd0a30820fa01 239 Pfam PF06149 Protein of unknown function (DUF969) 1 219 3.5E-85 T 16-09-2016 IPR010374 Protein of unknown function DUF969 Spa2297_RS31290 68d9c7d0c8d82da93d6fd0a30820fa01 239 PANTHER PTHR41293:SF1 1 237 7.6E-115 T 16-09-2016 Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 Pfam PF12802 MarR family 111 162 1.6E-12 T 16-09-2016 Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 Gene3D G3DSA:1.10.10.10 5 40 8.3E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 PANTHER PTHR10948 1 235 1.2E-35 T 16-09-2016 Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 SMART SM00418 104 182 0.009 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 SUPERFAMILY SSF46785 87 171 3.6E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 Gene3D G3DSA:1.10.10.10 87 166 1.1E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS25015 0b0e58f8d3233ef9d191f2a5a9dd0f3b 250 Pfam PF13936 Helix-turn-helix domain 5 45 1.8E-13 T 16-09-2016 IPR025246 Transposase IS30-like HTH domain Spa2297_RS05330 e8a6d91ec8de54fc9e0ad7ce3237199f 124 Pfam PF13397 RNA polymerase-binding protein 4 107 6.5E-42 T 16-09-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 Spa2297_RS05330 e8a6d91ec8de54fc9e0ad7ce3237199f 124 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 1 110 28.559 T 16-09-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 Spa2297_RS25125 51c66bace7cd9c3c847d100d167107bd 161 Gene3D G3DSA:3.30.565.10 53 153 1.2E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25125 51c66bace7cd9c3c847d100d167107bd 161 Pfam PF13581 Histidine kinase-like ATPase domain 35 148 5.3E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25125 51c66bace7cd9c3c847d100d167107bd 161 SUPERFAMILY SSF55874 54 151 7.34E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS22475 20925d966c724e85dc9248045a9198be 146 Gene3D G3DSA:2.60.120.10 21 117 3.3E-23 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS22475 20925d966c724e85dc9248045a9198be 146 SUPERFAMILY SSF51182 20 130 1.26E-25 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS22475 20925d966c724e85dc9248045a9198be 146 PIRSF PIRSF016602 1 145 2.9E-59 T 16-09-2016 IPR016672 Polyketide biosynthesis protein CurC, predicted Spa2297_RS22475 20925d966c724e85dc9248045a9198be 146 Pfam PF07883 Cupin domain 42 108 1.8E-18 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS17970 45a69c6268e9ae7028ec016e1bb0eb46 143 PANTHER PTHR35526:SF1 1 142 5.2E-38 T 16-09-2016 Spa2297_RS17970 45a69c6268e9ae7028ec016e1bb0eb46 143 Pfam PF13581 Histidine kinase-like ATPase domain 8 133 1.6E-30 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS17970 45a69c6268e9ae7028ec016e1bb0eb46 143 PANTHER PTHR35526 1 142 5.2E-38 T 16-09-2016 Spa2297_RS30525 6d346a277bb255e6dfb666614b0a378a 250 PANTHER PTHR37461 1 250 8.6E-53 T 16-09-2016 Spa2297_RS30525 6d346a277bb255e6dfb666614b0a378a 250 Pfam PF13490 Putative zinc-finger 11 36 3.0E-6 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS30525 6d346a277bb255e6dfb666614b0a378a 250 Pfam PF10099 Anti-sigma-K factor rskA 58 245 8.8E-33 T 16-09-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 Spa2297_RS30525 6d346a277bb255e6dfb666614b0a378a 250 PANTHER PTHR37461:SF1 1 250 8.6E-53 T 16-09-2016 Spa2297_RS25195 54816e5a48144716751d41aef85b431e 382 Gene3D G3DSA:3.40.710.10 54 367 6.9E-72 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS25195 54816e5a48144716751d41aef85b431e 382 PANTHER PTHR22935 68 367 3.9E-56 T 16-09-2016 Spa2297_RS25195 54816e5a48144716751d41aef85b431e 382 PANTHER PTHR22935:SF69 68 367 3.9E-56 T 16-09-2016 Spa2297_RS25195 54816e5a48144716751d41aef85b431e 382 Pfam PF00144 Beta-lactamase 51 350 1.4E-52 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS25195 54816e5a48144716751d41aef85b431e 382 SUPERFAMILY SSF56601 50 358 1.71E-67 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS08960 6f5035a75e1419380f1b2d541dc33050 234 PANTHER PTHR10108 7 125 2.6E-21 T 16-09-2016 Spa2297_RS08960 6f5035a75e1419380f1b2d541dc33050 234 Pfam PF08241 Methyltransferase domain 22 122 8.9E-20 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS08960 6f5035a75e1419380f1b2d541dc33050 234 Gene3D G3DSA:3.40.50.150 9 137 1.6E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08960 6f5035a75e1419380f1b2d541dc33050 234 SUPERFAMILY SSF53335 7 192 1.05E-31 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08960 6f5035a75e1419380f1b2d541dc33050 234 PANTHER PTHR10108:SF705 7 125 2.6E-21 T 16-09-2016 Spa2297_RS02995 d74ff8a0efd4b3650befc302af35302b 229 SUPERFAMILY SSF102522 5 118 1.07E-7 T 16-09-2016 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal Spa2297_RS02995 d74ff8a0efd4b3650befc302af35302b 229 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 5 139 2.1E-13 T 16-09-2016 IPR002747 SAM-dependent chlorinase/fluorinase Spa2297_RS02995 d74ff8a0efd4b3650befc302af35302b 229 Gene3D G3DSA:2.40.30.90 116 185 1.3E-4 T 16-09-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 16-09-2016 IPR030659 SecY conserved site Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 Pfam PF00344 SecY translocase 73 418 5.6E-113 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 429 1.3E-139 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.6E-102 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 Gene3D G3DSA:1.10.3370.10 2 435 3.0E-150 T 16-09-2016 IPR023201 SecY subunit domain Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PIRSF PIRSF004557 1 435 4.1E-121 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PANTHER PTHR10906 1 435 2.5E-183 T 16-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 PANTHER PTHR10906:SF2 1 435 2.5E-183 T 16-09-2016 Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 28.604 T 16-09-2016 IPR026593 Protein translocase subunit SecY Spa2297_RS25545 0aa5d0aa053963c61f234520de2ea818 435 SUPERFAMILY SSF103491 2 424 2.09E-120 T 16-09-2016 IPR023201 SecY subunit domain Spa2297_RS12155 c206ec9b25acf967c21ae7cc2368a7df 313 Gene3D G3DSA:3.40.720.10 1 115 6.0E-19 T 16-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 Spa2297_RS12155 c206ec9b25acf967c21ae7cc2368a7df 313 SUPERFAMILY SSF53649 1 114 8.9E-20 T 16-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 Spa2297_RS12155 c206ec9b25acf967c21ae7cc2368a7df 313 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 1 182 1.6E-8 T 16-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Spa2297_RS01835 6d1eaa125e9c84b6dde8b8e0cb551b6e 177 PANTHER PTHR33452:SF1 1 162 1.1E-39 T 16-09-2016 Spa2297_RS01835 6d1eaa125e9c84b6dde8b8e0cb551b6e 177 PANTHER PTHR33452 1 162 1.1E-39 T 16-09-2016 Spa2297_RS01835 6d1eaa125e9c84b6dde8b8e0cb551b6e 177 Pfam PF07681 DoxX 5 96 3.5E-20 T 16-09-2016 IPR032808 DoxX family Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 PANTHER PTHR10108:SF730 247 257 2.3E-20 T 16-09-2016 Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 Gene3D G3DSA:3.40.50.150 22 162 1.6E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 SUPERFAMILY SSF53335 23 178 6.05E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 Pfam PF08241 Methyltransferase domain 61 150 2.6E-15 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 PANTHER PTHR10108 25 162 2.3E-20 T 16-09-2016 Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 PANTHER PTHR10108 247 257 2.3E-20 T 16-09-2016 Spa2297_RS18475 95545acb3289986aa8881554074f1d69 268 PANTHER PTHR10108:SF730 25 162 2.3E-20 T 16-09-2016 Spa2297_RS20195 19d38a6c44a4cfd47f588cf355e37f07 431 Gene3D G3DSA:2.60.40.10 324 422 3.6E-5 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS00440 0646b812d2dad7e26243b645e3d38289 290 PANTHER PTHR14859 48 277 3.2E-27 T 16-09-2016 IPR027317 PGAP2-interacting protein Spa2297_RS00440 0646b812d2dad7e26243b645e3d38289 290 SUPERFAMILY SSF56219 48 274 2.49E-29 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS00440 0646b812d2dad7e26243b645e3d38289 290 PANTHER PTHR14859:SF0 48 277 3.2E-27 T 16-09-2016 Spa2297_RS00440 0646b812d2dad7e26243b645e3d38289 290 Gene3D G3DSA:3.60.10.10 48 215 8.5E-10 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS00440 0646b812d2dad7e26243b645e3d38289 290 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 50 269 1.2E-16 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 SUPERFAMILY SSF54593 152 264 4.16E-18 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 Gene3D G3DSA:3.10.180.10 23 136 1.2E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 Gene3D G3DSA:3.10.180.10 150 265 8.2E-28 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 SUPERFAMILY SSF54593 23 135 7.2E-14 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 PANTHER PTHR33993:SF3 2 269 1.4E-115 T 16-09-2016 Spa2297_RS24790 052b92c8d612c19d839d4cce02cf1c0b 279 PANTHER PTHR33993 2 269 1.4E-115 T 16-09-2016 Spa2297_RS02965 78b3ade23cf63d4b73d477d18e8e57e8 279 Gene3D G3DSA:3.60.130.10 104 278 2.7E-17 T 16-09-2016 Spa2297_RS02965 78b3ade23cf63d4b73d477d18e8e57e8 279 SUPERFAMILY SSF51197 66 278 1.83E-18 T 16-09-2016 Spa2297_RS02965 78b3ade23cf63d4b73d477d18e8e57e8 279 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 60 276 1.2E-9 T 16-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 Spa2297_RS30710 cacfb8adc22f9c6b41befcc048e5cbc0 118 Pfam PF05331 Protein of unknown function (DUF742) 8 118 5.9E-41 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS30710 cacfb8adc22f9c6b41befcc048e5cbc0 118 PANTHER PTHR36221 9 118 1.0E-39 T 16-09-2016 Spa2297_RS26575 c42657878498364d4891b7b2d6b5d4a3 313 SUPERFAMILY SSF52151 130 238 9.42E-9 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS26575 c42657878498364d4891b7b2d6b5d4a3 313 SUPERFAMILY SSF52151 15 86 9.42E-9 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 Gene3D G3DSA:3.40.50.150 18 262 1.7E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 PANTHER PTHR11579:SF0 5 53 5.4E-26 T 16-09-2016 Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 PANTHER PTHR11579:SF0 96 227 5.4E-26 T 16-09-2016 Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 SUPERFAMILY SSF53335 89 230 1.82E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 SUPERFAMILY SSF53335 10 47 1.82E-24 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 126 228 1.6E-16 T 16-09-2016 Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 PANTHER PTHR11579 5 53 5.4E-26 T 16-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Spa2297_RS12285 047627a561985e82d33010db5dd0fca1 400 PANTHER PTHR11579 96 227 5.4E-26 T 16-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Spa2297_RS26245 cd61bd4b63993e3f7e4161adc00a9ee2 368 PANTHER PTHR38479:SF2 8 368 2.3E-125 T 16-09-2016 Spa2297_RS26245 cd61bd4b63993e3f7e4161adc00a9ee2 368 Pfam PF06224 Winged helix DNA-binding domain 39 351 5.4E-71 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS26245 cd61bd4b63993e3f7e4161adc00a9ee2 368 PANTHER PTHR38479 8 368 2.3E-125 T 16-09-2016 Spa2297_RS29150 0e01cb911830a75c7fc45862a6c58740 316 PANTHER PTHR30238:SF0 2 316 1.7E-162 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS29150 0e01cb911830a75c7fc45862a6c58740 316 PANTHER PTHR30238 2 316 1.7E-162 T 16-09-2016 Spa2297_RS29150 0e01cb911830a75c7fc45862a6c58740 316 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 311 3.4E-115 T 16-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Spa2297_RS29150 0e01cb911830a75c7fc45862a6c58740 316 Pfam PF03741 Integral membrane protein TerC family 68 274 1.3E-55 T 16-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 Spa2297_RS14265 f2e8e6915e557f910ee5c1b4b0b214fb 94 PANTHER PTHR40040 9 90 1.1E-13 T 16-09-2016 Spa2297_RS14265 f2e8e6915e557f910ee5c1b4b0b214fb 94 Pfam PF13828 Domain of unknown function (DUF4190) 18 78 1.0E-10 T 16-09-2016 IPR025241 Domain of unknown function DUF4190 Spa2297_RS29155 542ec269c6ce60e5d6394fa3a2d644f4 187 Pfam PF03358 NADPH-dependent FMN reductase 4 149 1.2E-36 T 16-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spa2297_RS29155 542ec269c6ce60e5d6394fa3a2d644f4 187 SUPERFAMILY SSF52218 4 177 8.93E-43 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS29155 542ec269c6ce60e5d6394fa3a2d644f4 187 PANTHER PTHR30543:SF6 1 183 1.0E-68 T 16-09-2016 Spa2297_RS29155 542ec269c6ce60e5d6394fa3a2d644f4 187 Gene3D G3DSA:3.40.50.360 3 178 4.1E-49 T 16-09-2016 IPR029039 Flavoprotein-like domain Spa2297_RS29155 542ec269c6ce60e5d6394fa3a2d644f4 187 PANTHER PTHR30543 1 183 1.0E-68 T 16-09-2016 Spa2297_RS11730 5574630e8d410f8e8f3b285f50cbb8c0 263 Pfam PF15698 Phosphatase 12 261 7.9E-110 T 16-09-2016 IPR031423 Uncharacterised phosphatase SCO2771 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- Spa2297_RS21065 afe8362cce34e9d648e41f67d4a58645 234 Pfam PF03006 Haemolysin-III related 29 226 3.2E-45 T 16-09-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 Spa2297_RS21065 afe8362cce34e9d648e41f67d4a58645 234 PANTHER PTHR20855:SF3 37 229 1.5E-45 T 16-09-2016 IPR005744 Hly-III GO:0016021|GO:0019835 Spa2297_RS21065 afe8362cce34e9d648e41f67d4a58645 234 PANTHER PTHR20855 37 229 1.5E-45 T 16-09-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 Spa2297_RS16630 70642e6c3e02d0bc990e023428d37ae8 262 PANTHER PTHR22916 4 250 1.6E-27 T 16-09-2016 Spa2297_RS16630 70642e6c3e02d0bc990e023428d37ae8 262 Gene3D G3DSA:3.90.550.10 7 224 4.1E-26 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16630 70642e6c3e02d0bc990e023428d37ae8 262 SUPERFAMILY SSF53448 3 202 6.65E-26 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS16630 70642e6c3e02d0bc990e023428d37ae8 262 Pfam PF00535 Glycosyl transferase family 2 8 114 3.0E-9 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 12 197 1.2E-44 T 16-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 PANTHER PTHR23407:SF1 3 204 2.4E-47 T 16-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 12 197 2.2E-36 T 16-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 SUPERFAMILY SSF100950 11 203 1.13E-41 T 16-09-2016 Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 PIRSF PIRSF006806 9 200 7.4E-31 T 16-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 Gene3D G3DSA:3.40.50.10420 11 203 1.2E-49 T 16-09-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain Spa2297_RS13860 56a4416fa250071e99f4111c7c2bfc30 204 PANTHER PTHR23407 3 204 2.4E-47 T 16-09-2016 Spa2297_RS12455 dba13eff7e6a1990f86f2036d1b1d9a5 92 PANTHER PTHR14986 1 90 5.3E-28 T 16-09-2016 Spa2297_RS12455 dba13eff7e6a1990f86f2036d1b1d9a5 92 Gene3D G3DSA:3.10.20.30 3 88 2.1E-29 T 16-09-2016 IPR012675 Beta-grasp domain Spa2297_RS12455 dba13eff7e6a1990f86f2036d1b1d9a5 92 Pfam PF02597 ThiS family 5 90 3.6E-19 T 16-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Spa2297_RS12455 dba13eff7e6a1990f86f2036d1b1d9a5 92 SUPERFAMILY SSF54285 1 90 5.89E-25 T 16-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Spa2297_RS09855 4e7b370a62de1bdf8f36098638701921 214 PANTHER PTHR24094:SF14 12 214 5.4E-93 T 16-09-2016 Spa2297_RS09855 4e7b370a62de1bdf8f36098638701921 214 Pfam PF07510 Protein of unknown function (DUF1524) 114 207 2.4E-7 T 16-09-2016 IPR011089 Domain of unknown function DUF1524 Spa2297_RS09855 4e7b370a62de1bdf8f36098638701921 214 PANTHER PTHR24094 12 214 5.4E-93 T 16-09-2016 Spa2297_RS17340 889580ddead3dcf3d1420092cd2c91b3 243 Gene3D G3DSA:3.90.1580.10 91 195 5.0E-17 T 16-09-2016 IPR005532 Sulfatase-modifying factor enzyme Spa2297_RS17340 889580ddead3dcf3d1420092cd2c91b3 243 Gene3D G3DSA:3.90.1580.10 22 64 9.8E-4 T 16-09-2016 IPR005532 Sulfatase-modifying factor enzyme Spa2297_RS17340 889580ddead3dcf3d1420092cd2c91b3 243 SUPERFAMILY SSF56436 24 188 4.0E-21 T 16-09-2016 IPR016187 C-type lectin fold Spa2297_RS17340 889580ddead3dcf3d1420092cd2c91b3 243 Pfam PF03781 Sulfatase-modifying factor enzyme 1 91 182 7.4E-9 T 16-09-2016 IPR005532 Sulfatase-modifying factor enzyme Spa2297_RS26200 233802ba97ff9ccae265191266269bbf 344 Pfam PF00535 Glycosyl transferase family 2 16 126 3.1E-13 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS26200 233802ba97ff9ccae265191266269bbf 344 PANTHER PTHR22916 16 205 8.6E-21 T 16-09-2016 Spa2297_RS26200 233802ba97ff9ccae265191266269bbf 344 SUPERFAMILY SSF53448 15 209 2.16E-30 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS26200 233802ba97ff9ccae265191266269bbf 344 Gene3D G3DSA:3.90.550.10 16 204 4.1E-22 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS18190 1bbe5cb128d0e2140f1f768f5b5a1c31 162 Pfam PF11377 Protein of unknown function (DUF3180) 9 149 1.5E-35 T 16-09-2016 IPR021517 Protein of unknown function DUF3180 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 Gene3D G3DSA:3.20.20.30 20 358 6.7E-94 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 21 359 5.6E-130 T 16-09-2016 IPR019949 Luciferase family oxidoreductase, group 1 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 PANTHER PTHR30137 13 359 1.4E-139 T 16-09-2016 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 PANTHER PTHR30137:SF2 13 359 1.4E-139 T 16-09-2016 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 Pfam PF00296 Luciferase-like monooxygenase 23 333 3.0E-41 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS12015 e30cdafe9b71c41fdbaa77f51d2c6a72 365 SUPERFAMILY SSF51679 20 358 1.41E-79 T 16-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Spa2297_RS32760 22403e19f1d4d5b35e95d1fd838d3bec 153 Pfam PF05834 Lycopene cyclase protein 1 152 6.5E-52 T 16-09-2016 Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 Pfam PF07690 Major Facilitator Superfamily 9 331 3.3E-40 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 PANTHER PTHR23501 1 402 5.1E-161 T 16-09-2016 Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 PANTHER PTHR23501:SF4 1 402 5.1E-161 T 16-09-2016 Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 SUPERFAMILY SSF103473 3 378 2.49E-55 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 Gene3D G3DSA:1.20.1250.20 5 187 8.6E-29 T 16-09-2016 Spa2297_RS01125 6d7e65dd7d50a0a8566a5580e8366268 403 Gene3D G3DSA:1.20.1250.20 193 378 8.0E-15 T 16-09-2016 Spa2297_RS05465 61b9c7407e7afe5588a637588dfa2635 468 Pfam PF00860 Permease family 36 405 1.8E-69 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS05465 61b9c7407e7afe5588a637588dfa2635 468 PANTHER PTHR11119:SF49 1 433 4.1E-156 T 16-09-2016 Spa2297_RS05465 61b9c7407e7afe5588a637588dfa2635 468 PANTHER PTHR11119 1 433 4.1E-156 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS29060 c7d6ea1a2aa34a2c67680769006a4a61 71 PANTHER PTHR39324:SF1 1 71 4.7E-28 T 16-09-2016 Spa2297_RS29060 c7d6ea1a2aa34a2c67680769006a4a61 71 SUPERFAMILY SSF89807 3 68 5.36E-25 T 16-09-2016 IPR009923 Dodecin Spa2297_RS29060 c7d6ea1a2aa34a2c67680769006a4a61 71 Gene3D G3DSA:3.30.1660.10 2 69 1.2E-36 T 16-09-2016 IPR025543 Dodecin-like Spa2297_RS29060 c7d6ea1a2aa34a2c67680769006a4a61 71 Pfam PF07311 Dodecin 5 68 1.4E-28 T 16-09-2016 IPR009923 Dodecin Spa2297_RS29060 c7d6ea1a2aa34a2c67680769006a4a61 71 PANTHER PTHR39324 1 71 4.7E-28 T 16-09-2016 Spa2297_RS08355 14737d6ec375511e46391b1a1304e3a1 131 SUPERFAMILY SSF55298 6 128 3.46E-23 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS08355 14737d6ec375511e46391b1a1304e3a1 131 Gene3D G3DSA:3.30.1330.40 6 128 4.0E-29 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS08355 14737d6ec375511e46391b1a1304e3a1 131 Pfam PF01042 Endoribonuclease L-PSP 21 124 1.9E-13 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS08355 14737d6ec375511e46391b1a1304e3a1 131 PANTHER PTHR11803:SF7 7 127 1.3E-46 T 16-09-2016 Spa2297_RS08355 14737d6ec375511e46391b1a1304e3a1 131 PANTHER PTHR11803 7 127 1.3E-46 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS11100 d78fb0a63472144ba76c9653c6f52963 390 Pfam PF01757 Acyltransferase family 32 334 4.1E-18 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS11100 d78fb0a63472144ba76c9653c6f52963 390 PANTHER PTHR37312 15 368 2.4E-86 T 16-09-2016 Spa2297_RS19340 b045e3bd07f81835e50d9f9cd1f36429 258 PANTHER PTHR34216:SF3 1 222 6.6E-49 T 16-09-2016 Spa2297_RS19340 b045e3bd07f81835e50d9f9cd1f36429 258 SUPERFAMILY SSF88713 16 190 3.52E-33 T 16-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spa2297_RS19340 b045e3bd07f81835e50d9f9cd1f36429 258 PANTHER PTHR34216 1 222 6.6E-49 T 16-09-2016 Spa2297_RS19340 b045e3bd07f81835e50d9f9cd1f36429 258 Gene3D G3DSA:3.20.20.370 31 187 1.1E-24 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS19340 b045e3bd07f81835e50d9f9cd1f36429 258 Pfam PF01522 Polysaccharide deacetylase 54 185 1.4E-24 T 16-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 SUPERFAMILY SSF103473 31 443 1.57E-52 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 Pfam PF07690 Major Facilitator Superfamily 56 347 2.8E-35 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 PANTHER PTHR11360 34 441 1.2E-77 T 16-09-2016 Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 Gene3D G3DSA:1.20.1250.20 37 226 1.2E-21 T 16-09-2016 Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 Gene3D G3DSA:1.20.1250.20 263 444 3.7E-21 T 16-09-2016 Spa2297_RS27415 e33ff7e1f310de9961ca38b96b7ca03c 459 PANTHER PTHR11360:SF3 34 441 1.2E-77 T 16-09-2016 Spa2297_RS29260 5e3d644250083907e1d296ea25a0bcf6 338 Pfam PF13354 Beta-lactamase enzyme family 167 300 1.8E-5 T 16-09-2016 Spa2297_RS29260 5e3d644250083907e1d296ea25a0bcf6 338 SUPERFAMILY SSF56601 111 309 5.22E-26 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS29260 5e3d644250083907e1d296ea25a0bcf6 338 Gene3D G3DSA:3.40.710.10 111 327 3.7E-18 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 Gene3D G3DSA:3.40.630.30 138 278 7.6E-19 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 SUPERFAMILY SSF55729 8 277 1.6E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 Pfam PF13312 Domain of unknown function (DUF4081) 48 153 4.1E-43 T 16-09-2016 IPR025289 Domain of unknown function DUF4081 Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 Pfam PF00583 Acetyltransferase (GNAT) family 209 272 1.2E-8 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 PIRSF PIRSF021603 1 282 6.6E-139 T 16-09-2016 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 PANTHER PTHR23091:SF122 111 278 5.7E-46 T 16-09-2016 Spa2297_RS24120 abd5bd18822c2780da08856b56504e3f 282 PANTHER PTHR23091 111 278 5.7E-46 T 16-09-2016 Spa2297_RS00015 1dfb1ab00e08f98b071e63058faabd22 336 SUPERFAMILY SSF117892 55 186 5.89E-5 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS00015 1dfb1ab00e08f98b071e63058faabd22 336 Pfam PF01145 SPFH domain / Band 7 family 26 197 4.6E-17 T 16-09-2016 IPR001107 Band 7 domain Spa2297_RS20500 94778490eea7cf31d33215f5b4a3d862 154 Pfam PF05154 TM2 domain 88 136 1.5E-18 T 16-09-2016 IPR007829 TM2 domain Spa2297_RS00390 cefb2a04302ad42572aed8f4a1bf2e7e 224 Pfam PF14016 Protein of unknown function (DUF4232) 89 217 1.8E-20 T 16-09-2016 IPR025326 Protein of unknown function DUF4232 Spa2297_RS33375 0d0cc5f5c5afaa936c281e402ad8ffee 199 PANTHER PTHR10283 1 196 4.4E-49 T 16-09-2016 Spa2297_RS33375 0d0cc5f5c5afaa936c281e402ad8ffee 199 PRINTS PR00758 Arsenical pump membrane protein signature 101 124 1.6E-6 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS33375 0d0cc5f5c5afaa936c281e402ad8ffee 199 PRINTS PR00758 Arsenical pump membrane protein signature 28 52 1.6E-6 T 16-09-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spa2297_RS33375 0d0cc5f5c5afaa936c281e402ad8ffee 199 PANTHER PTHR10283:SF21 1 196 4.4E-49 T 16-09-2016 Spa2297_RS33375 0d0cc5f5c5afaa936c281e402ad8ffee 199 Pfam PF03600 Citrate transporter 1 149 3.9E-8 T 16-09-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Spa2297_RS09890 1fa4677318a19ed292485089ff743bfd 216 Gene3D G3DSA:1.20.1260.10 58 214 8.2E-58 T 16-09-2016 IPR012347 Ferritin-related Spa2297_RS09890 1fa4677318a19ed292485089ff743bfd 216 PANTHER PTHR36933 1 215 3.5E-37 T 16-09-2016 Spa2297_RS09890 1fa4677318a19ed292485089ff743bfd 216 Pfam PF03713 Domain of unknown function (DUF305) 63 213 4.5E-52 T 16-09-2016 IPR005183 Domain of unknown function DUF305 Spa2297_RS09890 1fa4677318a19ed292485089ff743bfd 216 PANTHER PTHR36933:SF1 1 215 3.5E-37 T 16-09-2016 Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 PANTHER PTHR33495:SF2 4 124 2.9E-33 T 16-09-2016 Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 5 112 3.2E-16 T 16-09-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 SUPERFAMILY SSF52091 10 116 4.12E-19 T 16-09-2016 IPR002645 STAS domain Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 Pfam PF13466 STAS domain 18 82 4.4E-11 T 16-09-2016 IPR002645 STAS domain Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 Gene3D G3DSA:3.30.750.24 6 118 1.3E-33 T 16-09-2016 IPR002645 STAS domain Spa2297_RS14395 079760126c3bad3d7828cb5b40d33bbc 126 PANTHER PTHR33495 4 124 2.9E-33 T 16-09-2016 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 PIRSF PIRSF001265 21 751 3.5E-261 T 16-09-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 31 744 7.7E-199 T 16-09-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 PANTHER PTHR31998:SF0 14 745 0.0 T 16-09-2016 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 PANTHER PTHR31998 14 745 0.0 T 16-09-2016 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 Pfam PF03030 Inorganic H+ pyrophosphatase 38 739 2.5E-235 T 16-09-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 Spa2297_RS17975 1ebac3f4a30c5e6deb377d6eaf1dd233 801 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 744 24.319 T 16-09-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 Spa2297_RS31585 e98e9f15a7fe9df7a6710743d3e9ed48 236 Pfam PF01925 Sulfite exporter TauE/SafE 10 231 4.7E-19 T 16-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 Spa2297_RS33110 a77634ee55380800ee4dd71285856817 236 PANTHER PTHR24095:SF175 164 236 1.4E-37 T 16-09-2016 Spa2297_RS33110 a77634ee55380800ee4dd71285856817 236 SUPERFAMILY SSF56801 108 226 8.85E-10 T 16-09-2016 Spa2297_RS33110 a77634ee55380800ee4dd71285856817 236 PANTHER PTHR24095 164 236 1.4E-37 T 16-09-2016 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 SUPERFAMILY SSF48403 13 136 7.46E-25 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 Gene3D G3DSA:1.25.40.20 13 138 1.6E-27 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 Pfam PF12796 Ankyrin repeats (3 copies) 16 105 1.3E-11 T 16-09-2016 IPR020683 Ankyrin repeat-containing domain Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 PRINTS PR01415 Ankyrin repeat signature 92 106 3.3E-6 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 PRINTS PR01415 Ankyrin repeat signature 42 57 3.3E-6 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 PANTHER PTHR24193 12 136 2.4E-26 T 16-09-2016 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 SMART SM00248 111 140 0.34 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 SMART SM00248 76 105 0.039 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS28430 024c122ff9febf0d5bc38a831700ebe8 140 SMART SM00248 41 70 7.0 T 16-09-2016 IPR002110 Ankyrin repeat GO:0005515 Spa2297_RS19695 7f5bc273f55660a0a77308bd3944b792 428 PANTHER PTHR24421:SF19 215 426 2.9E-109 T 16-09-2016 Spa2297_RS19695 7f5bc273f55660a0a77308bd3944b792 428 PANTHER PTHR24421 215 426 2.9E-109 T 16-09-2016 Spa2297_RS19695 7f5bc273f55660a0a77308bd3944b792 428 Pfam PF13796 Putative sensor 27 206 1.9E-31 T 16-09-2016 IPR025828 Putative sensor domain Spa2297_RS19695 7f5bc273f55660a0a77308bd3944b792 428 Pfam PF07730 Histidine kinase 235 300 9.0E-16 T 16-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spa2297_RS19695 7f5bc273f55660a0a77308bd3944b792 428 SUPERFAMILY SSF55874 317 420 1.17E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 Pfam PF13672 Protein phosphatase 2C 215 471 3.3E-22 T 16-09-2016 Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 PRINTS PR01217 Proline rich extensin signature 133 158 1.5E-9 T 16-09-2016 Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 PRINTS PR01217 Proline rich extensin signature 87 103 1.5E-9 T 16-09-2016 Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 PRINTS PR01217 Proline rich extensin signature 66 87 1.5E-9 T 16-09-2016 Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 PRINTS PR01217 Proline rich extensin signature 108 125 1.5E-9 T 16-09-2016 Spa2297_RS26085 c457f012d6a0ad412c851a2a531fdd3b 493 PRINTS PR01217 Proline rich extensin signature 50 62 1.5E-9 T 16-09-2016 Spa2297_RS16160 a57e0ffe46eda2ecc48a9de3bf0092f7 221 SMART SM00943 26 197 2.1E-29 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS16160 a57e0ffe46eda2ecc48a9de3bf0092f7 221 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 26 189 6.8E-19 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS02425 a039bd35565e4eb0118992e7b35f9236 381 PANTHER PTHR21310 62 375 1.6E-66 T 16-09-2016 Spa2297_RS02425 a039bd35565e4eb0118992e7b35f9236 381 Pfam PF01636 Phosphotransferase enzyme family 96 306 3.6E-17 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS02425 a039bd35565e4eb0118992e7b35f9236 381 Gene3D G3DSA:3.90.1200.10 178 298 4.7E-12 T 16-09-2016 Spa2297_RS02425 a039bd35565e4eb0118992e7b35f9236 381 PANTHER PTHR21310:SF14 62 375 1.6E-66 T 16-09-2016 Spa2297_RS02425 a039bd35565e4eb0118992e7b35f9236 381 SUPERFAMILY SSF56112 90 317 3.64E-26 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS03210 cb1ca4176ffbdba838d8034299f18196 318 Gene3D G3DSA:1.10.3720.10 32 301 3.2E-51 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS03210 cb1ca4176ffbdba838d8034299f18196 318 PANTHER PTHR30193:SF27 6 316 1.4E-204 T 16-09-2016 Spa2297_RS03210 cb1ca4176ffbdba838d8034299f18196 318 PANTHER PTHR30193 6 316 1.4E-204 T 16-09-2016 Spa2297_RS03210 cb1ca4176ffbdba838d8034299f18196 318 SUPERFAMILY SSF161098 32 313 7.59E-47 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS03210 cb1ca4176ffbdba838d8034299f18196 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 301 8.5E-18 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS05840 8e904b4e946b687b1272a82c0b15599c 152 Gene3D G3DSA:3.30.530.20 5 147 1.8E-16 T 16-09-2016 IPR023393 START-like domain Spa2297_RS05840 8e904b4e946b687b1272a82c0b15599c 152 SUPERFAMILY SSF55961 13 145 7.0E-18 T 16-09-2016 Spa2297_RS05840 8e904b4e946b687b1272a82c0b15599c 152 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 14 125 3.4E-9 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS01400 9c31c3846257a459130303718411a257 375 Pfam PF11991 Tryptophan dimethylallyltransferase 20 311 4.8E-11 T 16-09-2016 IPR017795 Aromatic prenyltransferase, DMATS type GO:0009820|GO:0050364 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 PIRSF PIRSF015601 4 248 3.3E-47 T 16-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 SUPERFAMILY SSF75217 78 248 5.23E-45 T 16-09-2016 IPR029028 Alpha/beta knot methyltransferases Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 Pfam PF04452 RNA methyltransferase 22 241 1.1E-61 T 16-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 SUPERFAMILY SSF88697 15 67 1.99E-9 T 16-09-2016 IPR015947 PUA-like domain Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 21 243 4.3E-32 T 16-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 PANTHER PTHR30027 1 249 3.8E-70 T 16-09-2016 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 PANTHER PTHR30027:SF3 1 249 3.8E-70 T 16-09-2016 Spa2297_RS10745 8ca538255a9ffa7780e3411f3628c517 249 Gene3D G3DSA:3.40.1280.10 5 248 3.2E-68 T 16-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 Gene3D G3DSA:3.60.21.10 149 250 1.4E-11 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 Gene3D G3DSA:3.60.21.10 46 116 1.4E-11 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 SUPERFAMILY SSF56300 41 302 4.52E-24 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 PANTHER PTHR31302 1 119 3.3E-57 T 16-09-2016 Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 PANTHER PTHR31302 149 309 3.3E-57 T 16-09-2016 Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 PANTHER PTHR31302:SF6 149 309 3.3E-57 T 16-09-2016 Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 PANTHER PTHR31302:SF6 1 119 3.3E-57 T 16-09-2016 Spa2297_RS17815 ca634a6ced04541cceeb4f908e8e0f58 310 Pfam PF00149 Calcineurin-like phosphoesterase 47 164 1.5E-5 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS09825 e13ffab3d8f89294cec38e36dd6ea18e 179 Gene3D G3DSA:3.40.630.30 3 161 1.3E-13 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09825 e13ffab3d8f89294cec38e36dd6ea18e 179 SUPERFAMILY SSF55729 10 169 1.38E-14 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16145 1d8c8831592610920eab152f29c19169 212 Gene3D G3DSA:3.30.565.10 53 169 3.4E-5 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16145 1d8c8831592610920eab152f29c19169 212 SUPERFAMILY SSF55874 74 170 2.54E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16145 1d8c8831592610920eab152f29c19169 212 Pfam PF13581 Histidine kinase-like ATPase domain 50 166 1.2E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS25800 93daa4f29a932c21d4943039b6faff20 429 Pfam PF01590 GAF domain 113 216 8.0E-6 T 16-09-2016 IPR003018 GAF domain GO:0005515 Spa2297_RS16380 3b1617089893571b032adc955710664a 160 PANTHER PTHR22769 7 115 6.9E-15 T 16-09-2016 Spa2297_RS16380 3b1617089893571b032adc955710664a 160 SUPERFAMILY SSF55811 2 113 1.18E-19 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS16380 3b1617089893571b032adc955710664a 160 Gene3D G3DSA:3.90.79.10 3 113 2.1E-19 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS16380 3b1617089893571b032adc955710664a 160 Pfam PF00293 NUDIX domain 9 95 1.6E-12 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS13215 28ff0c35027c2f6558ad145bde79dd05 188 Pfam PF03061 Thioesterase superfamily 43 113 1.0E-20 T 16-09-2016 IPR006683 Thioesterase domain Spa2297_RS13215 28ff0c35027c2f6558ad145bde79dd05 188 Gene3D G3DSA:3.10.129.10 23 174 4.9E-55 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS13215 28ff0c35027c2f6558ad145bde79dd05 188 SUPERFAMILY SSF54637 23 176 7.04E-45 T 16-09-2016 IPR029069 HotDog domain Spa2297_RS13215 28ff0c35027c2f6558ad145bde79dd05 188 PANTHER PTHR11049 14 185 5.7E-70 T 16-09-2016 Spa2297_RS11105 96531341565f251fa992f6994dc1c73f 177 Pfam PF13328 HD domain 26 93 2.5E-9 T 16-09-2016 IPR003607 HD/PDEase domain Spa2297_RS11105 96531341565f251fa992f6994dc1c73f 177 PANTHER PTHR21262 27 130 3.5E-16 T 16-09-2016 Spa2297_RS11105 96531341565f251fa992f6994dc1c73f 177 SUPERFAMILY SSF109604 22 158 4.92E-24 T 16-09-2016 Spa2297_RS23430 4e5e06a15eb1a69e3433d8423ed2018e 183 Gene3D G3DSA:3.40.50.850 2 136 5.5E-47 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS23430 4e5e06a15eb1a69e3433d8423ed2018e 183 PANTHER PTHR11080 1 135 1.3E-38 T 16-09-2016 Spa2297_RS23430 4e5e06a15eb1a69e3433d8423ed2018e 183 Pfam PF00857 Isochorismatase family 5 139 6.4E-42 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS23430 4e5e06a15eb1a69e3433d8423ed2018e 183 SUPERFAMILY SSF52499 2 136 1.57E-48 T 16-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 Spa2297_RS30545 61748f31b06599931fd65de8d84f1873 532 Pfam PF12831 FAD dependent oxidoreductase 6 510 9.7E-113 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30545 61748f31b06599931fd65de8d84f1873 532 SUPERFAMILY SSF51905 458 503 6.08E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30545 61748f31b06599931fd65de8d84f1873 532 SUPERFAMILY SSF51905 4 192 6.08E-23 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30545 61748f31b06599931fd65de8d84f1873 532 Gene3D G3DSA:3.50.50.60 5 239 1.2E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS30545 61748f31b06599931fd65de8d84f1873 532 Gene3D G3DSA:3.50.50.60 440 504 1.2E-19 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS20225 82db6001af75d5cddab649b287c7b5a2 351 SUPERFAMILY SSF54001 234 350 8.83E-43 T 16-09-2016 Spa2297_RS20225 82db6001af75d5cddab649b287c7b5a2 351 Pfam PF00877 NlpC/P60 family 251 341 2.2E-26 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS20225 82db6001af75d5cddab649b287c7b5a2 351 Gene3D G3DSA:3.90.1720.10 233 350 8.2E-45 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS20225 82db6001af75d5cddab649b287c7b5a2 351 PANTHER PTHR21666 124 133 6.0E-38 T 16-09-2016 Spa2297_RS20225 82db6001af75d5cddab649b287c7b5a2 351 PANTHER PTHR21666 242 351 6.0E-38 T 16-09-2016 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 7.1E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 7.1E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 7.1E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 7.1E-9 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PANTHER PTHR33164:SF1 1 160 4.8E-48 T 16-09-2016 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 Pfam PF12802 MarR family 39 99 2.1E-13 T 16-09-2016 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 SMART SM00347 33 136 7.1E-15 T 16-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 SUPERFAMILY SSF46785 4 150 6.93E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 Gene3D G3DSA:1.10.10.10 2 152 2.5E-35 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS13955 37615dfad70cbb8052fc7cccefa7d194 163 PANTHER PTHR33164 1 160 4.8E-48 T 16-09-2016 Spa2297_RS03155 424ee291c35615f9be065bafb13061dd 133 Pfam PF07179 SseB protein N-terminal domain 15 127 3.7E-15 T 16-09-2016 IPR009839 SseB protein N-terminal domain Spa2297_RS19350 352353db06655127847d98997c3d19c9 361 Pfam PF13480 Acetyltransferase (GNAT) domain 160 299 1.3E-39 T 16-09-2016 Spa2297_RS19350 352353db06655127847d98997c3d19c9 361 SUPERFAMILY SSF55729 165 318 5.09E-20 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS00080 fbb225d63031e0b1fcef51ff05281708 86 Gene3D G3DSA:4.10.520.10 2 69 1.7E-5 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS00080 fbb225d63031e0b1fcef51ff05281708 86 SUPERFAMILY SSF47729 3 72 3.09E-5 T 16-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 Spa2297_RS08880 d4063ea167ec7a55013695c422d0a0f1 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 129 2.3E-53 T 16-09-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Spa2297_RS08880 d4063ea167ec7a55013695c422d0a0f1 132 PIRSF PIRSF017385 1 131 6.2E-50 T 16-09-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Spa2297_RS24800 d2cfa83d4bc421372ba19485cd7beab9 352 Pfam PF11268 Protein of unknown function (DUF3071) 1 168 6.8E-55 T 16-09-2016 IPR021421 Protein of unknown function DUF3071 Spa2297_RS29330 424ec6e0542e6c0354eb75bc741e23c4 232 Pfam PF14219 Domain of unknown function (DUF4328) 58 216 3.9E-41 T 16-09-2016 IPR025565 Domain of unknown function DUF4328 Spa2297_RS16230 31975177eb5e5fdbce768ecb3a2a9ce7 239 Pfam PF12679 ABC-2 family transporter protein 52 168 7.4E-11 T 16-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 39 218 4.1E-48 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 PANTHER PTHR10672:SF17 16 260 3.4E-128 T 16-09-2016 Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 Gene3D G3DSA:3.40.225.10 32 243 1.0E-64 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 PANTHER PTHR10672 16 260 3.4E-128 T 16-09-2016 Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 SUPERFAMILY SSF53639 30 249 2.35E-68 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS20190 246961223d615b557653d015c48f0f76 267 SMART SM01007 38 218 1.7E-57 T 16-09-2016 IPR001303 Class II aldolase/adducin N-terminal Spa2297_RS01250 c0f2ab25ca5bc28389069a44c1e6cad9 241 PANTHER PTHR28047 1 232 4.3E-80 T 16-09-2016 Spa2297_RS01250 c0f2ab25ca5bc28389069a44c1e6cad9 241 PANTHER PTHR28047:SF1 1 232 4.3E-80 T 16-09-2016 Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.2E-64 T 16-09-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 Gene3D G3DSA:1.10.455.10 8 156 3.5E-60 T 16-09-2016 IPR023798 Ribosomal protein S7 domain Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.9E-59 T 16-09-2016 IPR023798 Ribosomal protein S7 domain Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 PIRSF PIRSF002122 7 156 1.5E-55 T 16-09-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.671 T 16-09-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 SUPERFAMILY SSF47973 1 149 3.66E-57 T 16-09-2016 IPR023798 Ribosomal protein S7 domain Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 16-09-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Spa2297_RS19670 ee64cb09aaad64a9c40834cb18126495 156 PANTHER PTHR11205 1 156 3.2E-85 T 16-09-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 Spa2297_RS17335 dd138670b6a3a61799860f8b21b77aa4 132 Gene3D G3DSA:3.40.50.1010 6 116 9.0E-4 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS17335 dd138670b6a3a61799860f8b21b77aa4 132 SUPERFAMILY SSF88723 6 119 1.18E-10 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS25305 0d590373e65d0900acf70d5daa731bbe 366 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 265 1.4E-47 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS25305 0d590373e65d0900acf70d5daa731bbe 366 PANTHER PTHR33392 9 357 9.9E-133 T 16-09-2016 Spa2297_RS25305 0d590373e65d0900acf70d5daa731bbe 366 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 108 265 2.1E-59 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS25305 0d590373e65d0900acf70d5daa731bbe 366 PANTHER PTHR33392:SF7 9 357 9.9E-133 T 16-09-2016 Spa2297_RS25945 9cc630e3a435f28ddfaf33cd1b8df95f 302 Gene3D G3DSA:3.20.20.330 2 300 5.5E-90 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS25945 9cc630e3a435f28ddfaf33cd1b8df95f 302 Pfam PF02574 Homocysteine S-methyltransferase 15 298 9.4E-67 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS25945 9cc630e3a435f28ddfaf33cd1b8df95f 302 PANTHER PTHR21091:SF123 8 300 1.9E-87 T 16-09-2016 Spa2297_RS25945 9cc630e3a435f28ddfaf33cd1b8df95f 302 SUPERFAMILY SSF82282 9 299 1.02E-79 T 16-09-2016 IPR003726 Homocysteine-binding domain Spa2297_RS25945 9cc630e3a435f28ddfaf33cd1b8df95f 302 PANTHER PTHR21091 8 300 1.9E-87 T 16-09-2016 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 Gene3D G3DSA:2.60.120.260 387 555 4.9E-13 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 SUPERFAMILY SSF49785 385 562 1.42E-11 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 72 336 9.5E-57 T 16-09-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 Gene3D G3DSA:3.40.50.1820 279 386 2.0E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 Gene3D G3DSA:3.40.50.1820 44 220 2.0E-55 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 374 549 4.2E-9 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 PANTHER PTHR11731 46 253 5.6E-86 T 16-09-2016 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 68 611 3.1E-160 T 16-09-2016 IPR005674 CocE/Serine esterase GO:0016787 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 SMART SM00939 359 587 9.2E-17 T 16-09-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 PANTHER PTHR11731:SF123 46 253 5.6E-86 T 16-09-2016 Spa2297_RS31050 5728e08f64b9f444e3e45ce005216488 621 SUPERFAMILY SSF53474 65 369 3.66E-43 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS09880 f4b15910b81daa93f9c2a1fccc08f4d1 210 Pfam PF13302 Acetyltransferase (GNAT) domain 47 182 9.6E-14 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS09880 f4b15910b81daa93f9c2a1fccc08f4d1 210 Gene3D G3DSA:3.40.630.30 45 203 9.3E-22 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09880 f4b15910b81daa93f9c2a1fccc08f4d1 210 SUPERFAMILY SSF55729 46 187 3.9E-19 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS09065 c53a4ef6f9428ef245ec86a7102ce093 488 Gene3D G3DSA:1.25.40.10 269 448 2.8E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS32020 9c04c509fce781f5a1c96ca45e149d0d 185 Pfam PF06912 Protein of unknown function (DUF1275) 2 171 4.0E-18 T 16-09-2016 IPR010699 Protein of unknown function DUF1275 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 PANTHER PTHR33154 1 126 2.2E-26 T 16-09-2016 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 SMART SM00418 36 114 1.0E-18 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 SUPERFAMILY SSF46785 26 114 6.3E-22 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 Pfam PF01022 Bacterial regulatory protein, arsR family 43 89 1.5E-10 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.0E-11 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 1.0E-11 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 85 100 1.0E-11 T 16-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spa2297_RS04800 85cf35d9590fe9c5bb155bd29c4d12cf 127 Gene3D G3DSA:1.10.10.10 24 119 6.9E-28 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS10620 5ca724172e15943f627d1de269f51d6c 305 SUPERFAMILY SSF52540 6 152 3.14E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS10620 5ca724172e15943f627d1de269f51d6c 305 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 144 4.5E-8 T 16-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spa2297_RS10620 5ca724172e15943f627d1de269f51d6c 305 Gene3D G3DSA:3.40.50.300 6 152 1.7E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS02170 ddea475af2af94ad5a2d1713c64863cc 209 SUPERFAMILY SSF51197 32 204 7.55E-42 T 16-09-2016 Spa2297_RS02170 ddea475af2af94ad5a2d1713c64863cc 209 Gene3D G3DSA:2.60.120.590 84 204 3.9E-17 T 16-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like Spa2297_RS02170 ddea475af2af94ad5a2d1713c64863cc 209 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 83 204 9.6E-14 T 16-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like Spa2297_RS02170 ddea475af2af94ad5a2d1713c64863cc 209 PANTHER PTHR31212:SF4 9 204 5.6E-61 T 16-09-2016 Spa2297_RS02170 ddea475af2af94ad5a2d1713c64863cc 209 PANTHER PTHR31212 9 204 5.6E-61 T 16-09-2016 IPR032854 Alkylated DNA repair protein alkB homologue 3 GO:0006281|GO:0006307|GO:0035552|GO:0051213 KEGG: 00260+1.14.11.-|KEGG: 00361+1.14.11.-|KEGG: 00904+1.14.11.- Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 PANTHER PTHR24220:SF364 254 281 2.6E-137 T 16-09-2016 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 PANTHER PTHR24220:SF364 3 237 2.6E-137 T 16-09-2016 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 SUPERFAMILY SSF52540 6 236 2.41E-56 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 16-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 Pfam PF00005 ABC transporter 30 172 1.7E-29 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 Gene3D G3DSA:3.40.50.300 4 238 3.0E-66 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 PANTHER PTHR24220 254 281 2.6E-137 T 16-09-2016 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 PANTHER PTHR24220 3 237 2.6E-137 T 16-09-2016 Spa2297_RS08415 2936e8dcee76c2054c4629d747d26522 324 SMART SM00382 38 222 1.6E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS09035 c9825048f0c7576f58324ab1ac63f873 173 Pfam PF14024 Protein of unknown function (DUF4240) 1 128 4.2E-44 T 16-09-2016 IPR025334 Domain of unknown function (DUF4240 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 SUPERFAMILY SSF50494 27 253 9.95E-64 T 16-09-2016 IPR009003 Peptidase S1, PA clan Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 73 78 - T 16-09-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 210 221 - T 16-09-2016 IPR033116 Serine proteases, trypsin family, serine active site Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 Gene3D G3DSA:2.40.10.10 36 70 1.6E-13 T 16-09-2016 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 PANTHER PTHR24276 4 253 1.3E-85 T 16-09-2016 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 SMART SM00020 35 255 1.3E-68 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 8.6E-13 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 209 221 8.6E-13 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 63 78 8.6E-13 T 16-09-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 Gene3D G3DSA:2.40.10.10 71 255 2.2E-54 T 16-09-2016 Spa2297_RS26250 15a864b392cb91e40e4f4e375a2e9456 261 Pfam PF00089 Trypsin 36 253 1.8E-54 T 16-09-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 Spa2297_RS30435 be58dc55440e89ac98c0d232b7b6b921 218 PANTHER PTHR10108:SF705 28 206 1.4E-22 T 16-09-2016 Spa2297_RS30435 be58dc55440e89ac98c0d232b7b6b921 218 Pfam PF08241 Methyltransferase domain 49 143 1.1E-19 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS30435 be58dc55440e89ac98c0d232b7b6b921 218 PANTHER PTHR10108 28 206 1.4E-22 T 16-09-2016 Spa2297_RS30435 be58dc55440e89ac98c0d232b7b6b921 218 SUPERFAMILY SSF53335 4 211 4.42E-36 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS30435 be58dc55440e89ac98c0d232b7b6b921 218 Gene3D G3DSA:3.40.50.150 6 185 2.1E-37 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS09200 49adb9e3bf6ce187d48dc19c016dd87a 71 Gene3D G3DSA:1.10.10.10 10 64 6.5E-4 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09200 49adb9e3bf6ce187d48dc19c016dd87a 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 58 1.6E-9 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS09200 49adb9e3bf6ce187d48dc19c016dd87a 71 Pfam PF12728 Helix-turn-helix domain 9 59 2.0E-9 T 16-09-2016 Spa2297_RS27450 c16031546cb944200c7d411f432f4b15 443 Pfam PF10011 Predicted membrane protein (DUF2254) 27 396 2.9E-97 T 16-09-2016 IPR018723 Protein of unknown function DUF2254, membrane Spa2297_RS24695 7202b842f9f7a2d102def31358bb0853 530 PANTHER PTHR11819 6 524 3.9E-244 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS24695 7202b842f9f7a2d102def31358bb0853 530 Pfam PF00474 Sodium:solute symporter family 38 453 3.8E-82 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS24695 7202b842f9f7a2d102def31358bb0853 530 PANTHER PTHR11819:SF13 6 524 3.9E-244 T 16-09-2016 Spa2297_RS20805 d0def7fcd8086e42ba90b09d281c74f9 228 Pfam PF10756 Bacterial PH domain 77 148 2.9E-8 T 16-09-2016 IPR019692 Protein of unknown function DUF2581 Spa2297_RS11310 0df881fb25d1318a6a85f4816cf707bd 448 SUPERFAMILY SSF53300 59 237 2.86E-21 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11310 0df881fb25d1318a6a85f4816cf707bd 448 SMART SM00327 60 237 2.9E-12 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11310 0df881fb25d1318a6a85f4816cf707bd 448 Pfam PF13768 von Willebrand factor type A domain 62 221 1.2E-10 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS11310 0df881fb25d1318a6a85f4816cf707bd 448 Gene3D G3DSA:3.40.50.410 63 229 2.5E-11 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS13070 6c220bd090cabdfacd72c5cb4f736191 335 Pfam PF01944 Stage II sporulation protein M 109 283 8.4E-37 T 16-09-2016 IPR002798 Stage II sporulation protein M-like Spa2297_RS13070 6c220bd090cabdfacd72c5cb4f736191 335 PANTHER PTHR35337 1 335 9.2E-56 T 16-09-2016 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 SUPERFAMILY SSF53187 92 309 1.19E-31 T 16-09-2016 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 Gene3D G3DSA:3.40.630.40 92 309 9.6E-35 T 16-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 PANTHER PTHR30404 128 311 3.2E-35 T 16-09-2016 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 PANTHER PTHR30404 89 105 3.2E-35 T 16-09-2016 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 SMART SM00646 178 306 2.2E-12 T 16-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 Spa2297_RS09670 71db9ed4196e1ceb53542d3772e87493 311 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 95 306 5.0E-33 T 16-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 Spa2297_RS09755 b4475964a631b0cfe5c22946d54f8e9b 697 Pfam PF09594 Protein of unknown function (DUF2029) 82 320 1.1E-32 T 16-09-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 Spa2297_RS09755 b4475964a631b0cfe5c22946d54f8e9b 697 PANTHER PTHR31310 283 665 1.0E-244 T 16-09-2016 Spa2297_RS09755 b4475964a631b0cfe5c22946d54f8e9b 697 PANTHER PTHR31310:SF6 283 665 1.0E-244 T 16-09-2016 Spa2297_RS09755 b4475964a631b0cfe5c22946d54f8e9b 697 Pfam PF14378 PAP2 superfamily 472 653 2.3E-46 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS19625 d9173da4eefc3af8bc7c49e0e451d52b 281 SUPERFAMILY SSF89392 171 259 9.42E-7 T 16-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spa2297_RS23005 80233209ffb8c3a77789f5a62ebac759 462 SUPERFAMILY SSF56112 170 452 6.94E-18 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS23005 80233209ffb8c3a77789f5a62ebac759 462 Gene3D G3DSA:3.90.1200.10 251 356 1.6E-4 T 16-09-2016 Spa2297_RS16590 7cc9a10a7dae324ec29a679ceb88917a 187 Hamap MF_00630 UPF0232 protein . 1 173 31.223 T 16-09-2016 IPR023007 Uncharacterised protein family UPF0232, actinobacteria Spa2297_RS16590 7cc9a10a7dae324ec29a679ceb88917a 187 Pfam PF05258 Protein of unknown function (DUF721) 70 158 1.3E-24 T 16-09-2016 IPR007922 Protein of unknown function DUF721/UPF0232 Spa2297_RS16590 7cc9a10a7dae324ec29a679ceb88917a 187 PANTHER PTHR36456 54 186 2.5E-34 T 16-09-2016 Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 Gene3D G3DSA:3.30.70.1230 189 374 8.2E-20 T 16-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 190 315 2.7E-13 T 16-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 SUPERFAMILY SSF55073 349 375 2.35E-30 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 SUPERFAMILY SSF55073 188 322 2.35E-30 T 16-09-2016 IPR029787 Nucleotide cyclase Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 Pfam PF16701 Adenylate cyclase regulatory domain 40 152 4.0E-8 T 16-09-2016 IPR032026 Adenylate cyclase regulatory domain Spa2297_RS20860 53f749a2b408b388ea0d3b51986aac2d 381 SMART SM00044 75 323 0.002 T 16-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spa2297_RS02725 2612b12fc9314414fdc4b0dac8c8b264 322 PANTHER PTHR37489 5 321 1.4E-130 T 16-09-2016 Spa2297_RS02725 2612b12fc9314414fdc4b0dac8c8b264 322 PANTHER PTHR37489:SF2 5 321 1.4E-130 T 16-09-2016 Spa2297_RS02725 2612b12fc9314414fdc4b0dac8c8b264 322 Pfam PF12006 Protein of unknown function (DUF3500) 9 309 2.3E-75 T 16-09-2016 IPR021889 Protein of unknown function DUF3500 Spa2297_RS14245 4b810777047cae2e00e05fb2cdd66ced 527 Pfam PF00474 Sodium:solute symporter family 33 418 6.8E-26 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS14245 4b810777047cae2e00e05fb2cdd66ced 527 PANTHER PTHR11819 2 502 1.8E-224 T 16-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS14245 4b810777047cae2e00e05fb2cdd66ced 527 PANTHER PTHR11819:SF141 2 502 1.8E-224 T 16-09-2016 Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 SUPERFAMILY SSF56112 86 248 1.93E-13 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 SUPERFAMILY SSF49785 442 546 1.11E-6 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 PANTHER PTHR24362:SF160 64 287 2.9E-13 T 16-09-2016 Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 Gene3D G3DSA:2.60.120.260 438 546 3.2E-7 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 Gene3D G3DSA:1.10.510.10 123 207 7.6E-8 T 16-09-2016 Spa2297_RS16510 4fa8465aac00f9ed70d3c2cceb37fdb2 564 PANTHER PTHR24362 64 287 2.9E-13 T 16-09-2016 Spa2297_RS29845 401326da2beaff707c7c9c85ae32a855 99 Pfam PF14019 Protein of unknown function (DUF4235) 13 89 9.2E-27 T 16-09-2016 IPR025329 Protein of unknown function DUF4235 Spa2297_RS01955 6d5bc0e9d70988d1e934eb76df90de5a 258 PANTHER PTHR33657:SF6 1 258 1.6E-121 T 16-09-2016 Spa2297_RS01955 6d5bc0e9d70988d1e934eb76df90de5a 258 Pfam PF05630 Necrosis inducing protein (NPP1) 47 247 3.5E-63 T 16-09-2016 IPR008701 Necrosis inducing protein Spa2297_RS01955 6d5bc0e9d70988d1e934eb76df90de5a 258 PANTHER PTHR33657 1 258 1.6E-121 T 16-09-2016 Spa2297_RS01955 6d5bc0e9d70988d1e934eb76df90de5a 258 PIRSF PIRSF029958 10 258 1.4E-111 T 16-09-2016 IPR008701 Necrosis inducing protein Spa2297_RS12245 c9789838e527bcad16d76a7fab569ab5 340 Gene3D G3DSA:1.25.40.10 197 219 7.0E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12245 c9789838e527bcad16d76a7fab569ab5 340 Gene3D G3DSA:1.25.40.10 101 134 7.0E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12245 c9789838e527bcad16d76a7fab569ab5 340 Gene3D G3DSA:1.25.40.10 18 60 7.0E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12245 c9789838e527bcad16d76a7fab569ab5 340 SUPERFAMILY SSF48452 19 130 5.52E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS12245 c9789838e527bcad16d76a7fab569ab5 340 Pfam PF02810 SEC-C motif 324 338 1.4E-6 T 16-09-2016 IPR004027 SEC-C motif Spa2297_RS22540 057bcd3886b91516720c22c05bde8e69 70 Pfam PF04149 Domain of unknown function (DUF397) 13 62 4.0E-20 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS18710 b2ff7ac0b1d6e50357637437650e263d 242 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 69 199 1.5E-25 T 16-09-2016 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain Spa2297_RS21415 b641e84dae5622710057e2f5e1c72eb7 458 PANTHER PTHR11785 13 454 3.4E-203 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS21415 b641e84dae5622710057e2f5e1c72eb7 458 Pfam PF00324 Amino acid permease 45 389 4.7E-33 T 16-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 Spa2297_RS21415 b641e84dae5622710057e2f5e1c72eb7 458 PIRSF PIRSF006060 5 457 9.3E-53 T 16-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 Spa2297_RS21415 b641e84dae5622710057e2f5e1c72eb7 458 PANTHER PTHR11785:SF197 13 454 3.4E-203 T 16-09-2016 Spa2297_RS27380 da87cb814723518628c84d938607b5ec 306 Pfam PF01040 UbiA prenyltransferase family 15 162 7.6E-21 T 16-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 Spa2297_RS27380 da87cb814723518628c84d938607b5ec 306 PANTHER PTHR11048 1 159 2.3E-20 T 16-09-2016 Spa2297_RS13180 adce5b8561724d165d57160e03428114 564 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 164 326 1.7E-44 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13180 adce5b8561724d165d57160e03428114 564 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 164 326 1.1E-37 T 16-09-2016 IPR004474 Cell envelope-related transcriptional attenuator domain Spa2297_RS13180 adce5b8561724d165d57160e03428114 564 PANTHER PTHR33392 25 558 3.6E-204 T 16-09-2016 Spa2297_RS13180 adce5b8561724d165d57160e03428114 564 PANTHER PTHR33392:SF7 25 558 3.6E-204 T 16-09-2016 Spa2297_RS13180 adce5b8561724d165d57160e03428114 564 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 441 534 5.8E-10 T 16-09-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spa2297_RS03780 1938fa8fff2b0153b20b2576fb7f3d09 129 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 4 118 1.3E-26 T 16-09-2016 IPR018727 Protein of unknown function DUF2267 Spa2297_RS09510 db9a4cb1b6702fc382e26ca142519abc 243 SMART SM00943 37 216 2.6E-38 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS09510 db9a4cb1b6702fc382e26ca142519abc 243 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 39 211 3.4E-25 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS24245 d1f7aaa5553125d8659f06814e8fdef5 151 Gene3D G3DSA:1.25.40.10 109 144 4.9E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS24245 d1f7aaa5553125d8659f06814e8fdef5 151 SUPERFAMILY SSF48452 95 145 2.11E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS05385 e1f79a8bd827c4cff481f2ee93d98397 206 SUPERFAMILY SSF52540 19 166 1.9E-16 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS05385 e1f79a8bd827c4cff481f2ee93d98397 206 Gene3D G3DSA:3.40.50.300 16 170 1.1E-20 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS03160 98e48047c44b62eb556abc2d064164f0 156 Gene3D G3DSA:3.30.530.20 3 151 5.1E-30 T 16-09-2016 IPR023393 START-like domain Spa2297_RS03160 98e48047c44b62eb556abc2d064164f0 156 SUPERFAMILY SSF55961 3 150 9.37E-31 T 16-09-2016 Spa2297_RS03160 98e48047c44b62eb556abc2d064164f0 156 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 12 150 1.5E-20 T 16-09-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 Spa2297_RS12070 d2a2f84d5fa95adff8ac17f4e2cae5d2 164 SUPERFAMILY SSF50891 7 149 6.45E-12 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS12070 d2a2f84d5fa95adff8ac17f4e2cae5d2 164 Pfam PF12903 Protein of unknown function (DUF3830) 8 163 2.2E-63 T 16-09-2016 IPR024532 Protein of unknown function DUF3830 Spa2297_RS05520 817741dba8325d8ae32bdb469f3f9580 347 SUPERFAMILY SSF100950 84 329 2.65E-56 T 16-09-2016 Spa2297_RS05520 817741dba8325d8ae32bdb469f3f9580 347 Pfam PF04198 Putative sugar-binding domain 81 329 6.3E-69 T 16-09-2016 IPR007324 Sugar-binding domain, putative GO:0030246 Spa2297_RS05520 817741dba8325d8ae32bdb469f3f9580 347 PANTHER PTHR34294:SF5 12 335 7.8E-133 T 16-09-2016 Spa2297_RS05520 817741dba8325d8ae32bdb469f3f9580 347 PANTHER PTHR34294 12 335 7.8E-133 T 16-09-2016 Spa2297_RS05520 817741dba8325d8ae32bdb469f3f9580 347 Gene3D G3DSA:3.40.50.1360 74 329 1.1E-69 T 16-09-2016 Spa2297_RS16680 807be7efe99502f8dc978ded8e631dd2 233 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 215 5.0E-86 T 16-09-2016 Spa2297_RS30495 84bfc3f6fb323374738d4bfa0ac2fdbe 217 SUPERFAMILY SSF53474 18 208 4.53E-24 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS30495 84bfc3f6fb323374738d4bfa0ac2fdbe 217 Pfam PF00326 Prolyl oligopeptidase family 145 201 6.9E-6 T 16-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Spa2297_RS30495 84bfc3f6fb323374738d4bfa0ac2fdbe 217 Pfam PF12697 Alpha/beta hydrolase family 25 139 1.9E-10 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS30495 84bfc3f6fb323374738d4bfa0ac2fdbe 217 Gene3D G3DSA:3.40.50.1820 21 203 1.4E-24 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03295 3b48f0e3fd052c218f8986d12f11f8d8 392 SUPERFAMILY SSF56601 47 368 3.35E-80 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS03295 3b48f0e3fd052c218f8986d12f11f8d8 392 PANTHER PTHR22935 46 350 6.1E-66 T 16-09-2016 Spa2297_RS03295 3b48f0e3fd052c218f8986d12f11f8d8 392 Pfam PF00144 Beta-lactamase 50 384 1.4E-60 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS03295 3b48f0e3fd052c218f8986d12f11f8d8 392 Gene3D G3DSA:3.40.710.10 56 351 4.2E-78 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS28120 706342e872ac1e80df4f5e98eac2d914 607 Pfam PF01066 CDP-alcohol phosphatidyltransferase 196 262 1.6E-8 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS28120 706342e872ac1e80df4f5e98eac2d914 607 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 240 262 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS22490 ac7cf4e8ba44a26d2337701b446b87fc 284 Gene3D G3DSA:3.40.1090.10 42 203 8.5E-8 T 16-09-2016 Spa2297_RS22490 ac7cf4e8ba44a26d2337701b446b87fc 284 SUPERFAMILY SSF52151 7 109 8.37E-32 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS22490 ac7cf4e8ba44a26d2337701b446b87fc 284 SUPERFAMILY SSF52151 139 211 8.37E-32 T 16-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 Spa2297_RS22490 ac7cf4e8ba44a26d2337701b446b87fc 284 Pfam PF01734 Patatin-like phospholipase 12 201 2.2E-17 T 16-09-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 Spa2297_RS22490 ac7cf4e8ba44a26d2337701b446b87fc 284 PANTHER PTHR14226 8 210 5.7E-25 T 16-09-2016 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 SUPERFAMILY SSF48264 11 401 1.01E-53 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PANTHER PTHR11712:SF234 4 401 1.3E-168 T 16-09-2016 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PANTHER PTHR11712 4 401 1.3E-168 T 16-09-2016 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 Gene3D G3DSA:1.10.630.10 8 402 4.5E-82 T 16-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PRINTS PR00359 B-class P450 signature 337 346 1.7E-17 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PRINTS PR00359 B-class P450 signature 290 317 1.7E-17 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PRINTS PR00359 B-class P450 signature 143 159 1.7E-17 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS01650 a5161d7feaec5973444a3e55ffdec576 410 PRINTS PR00359 B-class P450 signature 194 216 1.7E-17 T 16-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Spa2297_RS26895 ff3839860bfaba3379752791b77418cf 164 Pfam PF00293 NUDIX domain 19 132 9.3E-16 T 16-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 Spa2297_RS26895 ff3839860bfaba3379752791b77418cf 164 Gene3D G3DSA:3.90.79.10 16 144 1.1E-21 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS26895 ff3839860bfaba3379752791b77418cf 164 SUPERFAMILY SSF55811 17 143 8.26E-22 T 16-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 Spa2297_RS06895 05279bc3a8e77f5b25265a6e0cbb71b3 399 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 91 211 8.6E-8 T 16-09-2016 Spa2297_RS06895 05279bc3a8e77f5b25265a6e0cbb71b3 399 PANTHER PTHR12468:SF3 47 218 1.2E-94 T 16-09-2016 Spa2297_RS06895 05279bc3a8e77f5b25265a6e0cbb71b3 399 PANTHER PTHR12468 47 218 1.2E-94 T 16-09-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 Spa2297_RS28935 d2868a73a54954b1a5cedfa3d80d4d08 216 Pfam PF13490 Putative zinc-finger 9 37 2.2E-7 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS06040 7e6b14f0fb40a82313fd6fa75e9a4ee9 238 Pfam PF03734 L,D-transpeptidase catalytic domain 82 219 4.9E-5 T 16-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 Spa2297_RS06040 7e6b14f0fb40a82313fd6fa75e9a4ee9 238 PANTHER PTHR38589:SF1 1 238 7.3E-61 T 16-09-2016 Spa2297_RS06040 7e6b14f0fb40a82313fd6fa75e9a4ee9 238 PANTHER PTHR38589 1 238 7.3E-61 T 16-09-2016 Spa2297_RS11030 14291e79a7d5e6361260693a462e2121 342 Pfam PF04085 rod shape-determining protein MreC 131 270 2.4E-34 T 16-09-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 Spa2297_RS11030 14291e79a7d5e6361260693a462e2121 342 PANTHER PTHR34138 1 342 1.1E-59 T 16-09-2016 Spa2297_RS11030 14291e79a7d5e6361260693a462e2121 342 PANTHER PTHR34138:SF1 1 342 1.1E-59 T 16-09-2016 Spa2297_RS29365 51173f3d3578669dbe96ac08df81932b 127 Pfam PF04134 Protein of unknown function, DUF393 7 115 2.6E-20 T 16-09-2016 IPR007263 Protein of unknown function DUF393 Spa2297_RS12035 11a377b23cff47fc5a606c6e8b9daeae 199 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 19 125 1.3E-5 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS29385 6957954a8d1ebc86c153445e08c5ffc8 378 SUPERFAMILY SSF81606 182 370 4.97E-8 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29385 6957954a8d1ebc86c153445e08c5ffc8 378 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 179 371 2.3E-36 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS29385 6957954a8d1ebc86c153445e08c5ffc8 378 PANTHER PTHR21021 1 16 2.4E-26 T 16-09-2016 Spa2297_RS29385 6957954a8d1ebc86c153445e08c5ffc8 378 PANTHER PTHR21021 126 377 2.4E-26 T 16-09-2016 Spa2297_RS29385 6957954a8d1ebc86c153445e08c5ffc8 378 SMART SM00331 151 371 6.1E-54 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS24380 86fc7cb5ea6c712eecc25fca4186ecd9 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 98 5.6E-12 T 16-09-2016 IPR008407 Branched-chain amino acid transport, AzlD Spa2297_RS27540 1696b0be36f4f57361b5bedb233360fb 279 PANTHER PTHR32243 1 279 2.8E-117 T 16-09-2016 Spa2297_RS27540 1696b0be36f4f57361b5bedb233360fb 279 PANTHER PTHR32243:SF18 1 279 2.8E-117 T 16-09-2016 Spa2297_RS27540 1696b0be36f4f57361b5bedb233360fb 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 273 7.4E-21 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27540 1696b0be36f4f57361b5bedb233360fb 279 Gene3D G3DSA:1.10.3720.10 8 267 1.3E-67 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS27540 1696b0be36f4f57361b5bedb233360fb 279 SUPERFAMILY SSF161098 6 279 3.74E-70 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS30150 6ebf69c232e91fcb59260bc803a73cff 420 PANTHER PTHR33744:SF4 90 419 3.1E-60 T 16-09-2016 Spa2297_RS30150 6ebf69c232e91fcb59260bc803a73cff 420 Pfam PF13556 PucR C-terminal helix-turn-helix domain 356 413 7.7E-21 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS30150 6ebf69c232e91fcb59260bc803a73cff 420 PANTHER PTHR33744 90 419 3.1E-60 T 16-09-2016 Spa2297_RS03275 5ac4850b83a5f26321d58e83085f1f8e 136 PANTHER PTHR33570 1 132 1.4E-36 T 16-09-2016 Spa2297_RS03275 5ac4850b83a5f26321d58e83085f1f8e 136 Gene3D G3DSA:2.60.120.10 9 130 2.9E-27 T 16-09-2016 IPR014710 RmlC-like jelly roll fold Spa2297_RS03275 5ac4850b83a5f26321d58e83085f1f8e 136 SUPERFAMILY SSF51182 8 132 1.36E-26 T 16-09-2016 IPR011051 RmlC-like cupin domain Spa2297_RS03275 5ac4850b83a5f26321d58e83085f1f8e 136 Pfam PF07883 Cupin domain 39 102 2.9E-11 T 16-09-2016 IPR013096 Cupin 2, conserved barrel Spa2297_RS03275 5ac4850b83a5f26321d58e83085f1f8e 136 PANTHER PTHR33570:SF5 1 132 1.4E-36 T 16-09-2016 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 PIRSF PIRSF004532 17 337 7.4E-146 T 16-09-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 PANTHER PTHR30447:SF0 11 340 1.6E-184 T 16-09-2016 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 2.5E-117 T 16-09-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 SUPERFAMILY SSF56655 17 329 3.26E-112 T 16-09-2016 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 PANTHER PTHR30447 11 340 1.6E-184 T 16-09-2016 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 3.4E-143 T 16-09-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 Gene3D G3DSA:3.30.540.10 17 189 5.3E-65 T 16-09-2016 Spa2297_RS21370 33d2643c2953f170c43f0a40d3340840 343 Gene3D G3DSA:3.30.540.10 190 337 1.1E-44 T 16-09-2016 Spa2297_RS25290 20412e069cb36c2c2bfb72265c962199 140 Gene3D G3DSA:3.40.50.1010 76 132 4.9E-4 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS28735 d65bcf9f591ed6f6f22735be1860b981 412 SUPERFAMILY SSF50969 157 405 5.65E-6 T 16-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 PANTHER PTHR30346 2 214 7.5E-48 T 16-09-2016 Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 Gene3D G3DSA:3.40.190.10 23 101 7.1E-11 T 16-09-2016 Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 PANTHER PTHR30346:SF0 2 214 7.5E-48 T 16-09-2016 Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 SUPERFAMILY SSF53850 6 196 9.31E-19 T 16-09-2016 Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 Pfam PF03466 LysR substrate binding domain 23 194 1.4E-19 T 16-09-2016 IPR005119 LysR, substrate-binding Spa2297_RS03770 057fcd632218db3926af358dccb5b185 267 Gene3D G3DSA:3.40.190.10 132 169 2.1E-4 T 16-09-2016 Spa2297_RS22210 e71979c0d2a571a9ecd6935eaa4a835f 192 Gene3D G3DSA:3.40.80.10 26 189 9.4E-17 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS22210 e71979c0d2a571a9ecd6935eaa4a835f 192 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 35 175 2.5E-16 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS22210 e71979c0d2a571a9ecd6935eaa4a835f 192 SUPERFAMILY SSF55846 15 188 6.15E-25 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS22210 e71979c0d2a571a9ecd6935eaa4a835f 192 SMART SM00644 23 176 2.3E-26 T 16-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Spa2297_RS28900 93a2c407614e86dac3faa123f7b0a23b 300 PANTHER PTHR30193 7 300 1.5E-137 T 16-09-2016 Spa2297_RS28900 93a2c407614e86dac3faa123f7b0a23b 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 293 4.9E-13 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28900 93a2c407614e86dac3faa123f7b0a23b 300 SUPERFAMILY SSF161098 61 290 4.32E-56 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28900 93a2c407614e86dac3faa123f7b0a23b 300 Gene3D G3DSA:1.10.3720.10 67 298 9.3E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS28900 93a2c407614e86dac3faa123f7b0a23b 300 PANTHER PTHR30193:SF2 7 300 1.5E-137 T 16-09-2016 Spa2297_RS01995 3fcf6fff56694fa4147c32f9c8b9df1e 90 Pfam PF17196 Protein of unknown function (DUF5133) 1 65 5.6E-24 T 16-09-2016 IPR033457 Protein of unknown function DUF5133 Spa2297_RS12985 b5e957254b256473f4b187e8620daf88 400 PANTHER PTHR30528 8 400 5.5E-128 T 16-09-2016 Spa2297_RS12985 b5e957254b256473f4b187e8620daf88 400 Pfam PF06224 Winged helix DNA-binding domain 40 371 3.5E-61 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS13510 2c78ed1fa10275f4a9b6bc850eb6959b 153 Pfam PF04341 Protein of unknown function, DUF485 56 141 8.9E-19 T 16-09-2016 IPR007436 Protein of unknown function DUF485 Spa2297_RS31010 76b5970ba94224de260d8558aa29d8c3 217 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 148 8.6E-22 T 16-09-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 Spa2297_RS31010 76b5970ba94224de260d8558aa29d8c3 217 Gene3D G3DSA:1.20.120.450 2 58 2.0E-7 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS31010 76b5970ba94224de260d8558aa29d8c3 217 SUPERFAMILY SSF109854 2 152 1.07E-12 T 16-09-2016 Spa2297_RS08270 9af8d99a16575199bf4cf4f2cc605c8d 460 Pfam PF03747 ADP-ribosylglycohydrolase 111 420 5.5E-60 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS08270 9af8d99a16575199bf4cf4f2cc605c8d 460 SUPERFAMILY SSF101478 108 428 1.96E-43 T 16-09-2016 IPR005502 ADP-ribosylation/Crystallin J1 Spa2297_RS28145 910069bf733b040ceb3be8bb473d2d0e 309 Pfam PF01061 ABC-2 type transporter 61 267 5.2E-17 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS28145 910069bf733b040ceb3be8bb473d2d0e 309 PANTHER PTHR30294 2 308 9.6E-91 T 16-09-2016 Spa2297_RS28145 910069bf733b040ceb3be8bb473d2d0e 309 PANTHER PTHR30294:SF14 2 308 9.6E-91 T 16-09-2016 Spa2297_RS27505 8825d23abcf1ac64b32b19d4b77a08dd 358 PANTHER PTHR32208:SF28 142 343 1.9E-48 T 16-09-2016 Spa2297_RS27505 8825d23abcf1ac64b32b19d4b77a08dd 358 PANTHER PTHR32208 142 343 1.9E-48 T 16-09-2016 Spa2297_RS27505 8825d23abcf1ac64b32b19d4b77a08dd 358 Pfam PF09362 Domain of unknown function (DUF1996) 101 316 4.9E-47 T 16-09-2016 IPR018535 Domain of unknown function DUF1996 Spa2297_RS06205 08d008c97cd96def1ac103949ecc6373 334 Pfam PF10708 Protein of unknown function (DUF2510) 5 34 4.2E-11 T 16-09-2016 IPR018929 Domain of unknown function DUF2510 Spa2297_RS17205 869295be0fd59f3de6e0f49b45cf1f14 430 PANTHER PTHR31310:SF7 1 360 2.1E-80 T 16-09-2016 Spa2297_RS17205 869295be0fd59f3de6e0f49b45cf1f14 430 PANTHER PTHR31310 1 360 2.1E-80 T 16-09-2016 Spa2297_RS17205 869295be0fd59f3de6e0f49b45cf1f14 430 Pfam PF14378 PAP2 superfamily 155 341 2.9E-20 T 16-09-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 Spa2297_RS07145 fb33972d43b57d4e042cd875248665b1 81 Pfam PF03777 Small secreted domain (DUF320) 25 80 3.6E-26 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS08320 fbec94f6398fe98bd63e305c6ccabe68 213 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 22 212 2.7E-60 T 16-09-2016 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein Spa2297_RS08320 fbec94f6398fe98bd63e305c6ccabe68 213 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 30 211 6.4E-53 T 16-09-2016 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp Spa2297_RS31150 44a671d4f1f7bee091576484569bc7f0 313 SUPERFAMILY SSF53474 9 253 7.27E-26 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31150 44a671d4f1f7bee091576484569bc7f0 313 Gene3D G3DSA:3.40.50.1820 18 283 4.4E-25 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS31150 44a671d4f1f7bee091576484569bc7f0 313 PANTHER PTHR10272 30 283 7.1E-20 T 16-09-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 Spa2297_RS31150 44a671d4f1f7bee091576484569bc7f0 313 Pfam PF07224 Chlorophyllase 35 146 5.9E-7 T 16-09-2016 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164|UniPathway: UPA00674 Spa2297_RS33950 2a9df7a80364f79fa39c633c779456ec 146 Pfam PF01636 Phosphotransferase enzyme family 13 89 1.0E-10 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS33950 2a9df7a80364f79fa39c633c779456ec 146 Gene3D G3DSA:3.90.1200.10 6 83 2.9E-11 T 16-09-2016 Spa2297_RS33950 2a9df7a80364f79fa39c633c779456ec 146 SUPERFAMILY SSF56112 3 99 6.27E-14 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS24500 e50a4f0e08a80fdae83e6c7123e74eff 97 Pfam PF14013 MT0933-like antitoxin protein 16 63 3.6E-15 T 16-09-2016 IPR028037 Antitoxin Rv0909/MT0933 Spa2297_RS02490 addea92360c643698466ceb171249c67 125 Pfam PF03860 Domain of Unknown Function (DUF326) 100 120 7.0E-6 T 16-09-2016 IPR005560 Protein of unknown function DUF326 Spa2297_RS02490 addea92360c643698466ceb171249c67 125 PANTHER PTHR37310 1 125 3.8E-29 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 SUPERFAMILY SSF53850 34 425 5.44E-52 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 Gene3D G3DSA:3.40.190.10 33 165 7.0E-15 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 PANTHER PTHR30061 6 425 5.4E-87 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 PANTHER PTHR30061:SF28 6 425 5.4E-87 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 Gene3D G3DSA:3.40.190.10 166 355 1.5E-24 T 16-09-2016 Spa2297_RS00725 0413d8e42fbd47a16e17c95f8ab98ef5 426 Pfam PF13416 Bacterial extracellular solute-binding protein 51 356 1.7E-28 T 16-09-2016 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 Pfam PF08241 Methyltransferase domain 81 173 2.1E-18 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 PANTHER PTHR10108:SF779 200 259 2.9E-31 T 16-09-2016 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 PANTHER PTHR10108:SF779 33 183 2.9E-31 T 16-09-2016 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 PANTHER PTHR10108 200 259 2.9E-31 T 16-09-2016 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 PANTHER PTHR10108 33 183 2.9E-31 T 16-09-2016 Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 Gene3D G3DSA:3.40.50.150 31 259 1.2E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS08110 e93e3e19006c158b7d7e7aed48e22e0a 274 SUPERFAMILY SSF53335 29 254 2.92E-34 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 PANTHER PTHR24322 12 193 2.1E-44 T 16-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 PIRSF PIRSF000094 2 259 6.7E-78 T 16-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 3.8E-64 T 16-09-2016 Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 PANTHER PTHR24322:SF317 12 193 2.1E-44 T 16-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 Gene3D G3DSA:3.40.50.720 4 257 9.4E-57 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26560 78f9d4d126046d4387e48656e3d3b4fe 259 SUPERFAMILY SSF51735 7 257 6.94E-50 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 PANTHER PTHR22748 1 259 1.4E-119 T 16-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 2.5E-81 T 16-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 PANTHER PTHR22748:SF7 1 259 1.4E-119 T 16-09-2016 Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 2.8E-21 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 SUPERFAMILY SSF56219 1 258 1.31E-69 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 8.7E-59 T 16-09-2016 Spa2297_RS26710 70859e6ad88e09523c8c370163622d5b 259 Gene3D G3DSA:3.60.10.10 1 258 9.6E-77 T 16-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase Spa2297_RS31940 4ef9f16c027fc1e4beed4b7ffe3e0283 270 PANTHER PTHR36852:SF1 23 270 5.3E-20 T 16-09-2016 Spa2297_RS31940 4ef9f16c027fc1e4beed4b7ffe3e0283 270 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 6 257 3.1E-43 T 16-09-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 Spa2297_RS31940 4ef9f16c027fc1e4beed4b7ffe3e0283 270 PANTHER PTHR36852 23 270 5.3E-20 T 16-09-2016 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.2E-24 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 1.2E-24 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 1.2E-24 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 1.2E-24 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 1.2E-24 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 SUPERFAMILY SSF50891 6 170 4.82E-57 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PANTHER PTHR11071 7 168 2.8E-67 T 16-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 Gene3D G3DSA:2.40.100.10 6 171 6.7E-58 T 16-09-2016 IPR029000 Cyclophilin-like domain Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 170 8.9E-43 T 16-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 PIRSF PIRSF001467 2 176 1.9E-52 T 16-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 Spa2297_RS16685 7c5e4c4bb88550301b8d5bf8d0a9d61c 177 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 16-09-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Spa2297_RS27845 2533b181a5fd4b597db076d1943a1719 322 PANTHER PTHR40761 3 292 2.9E-18 T 16-09-2016 Spa2297_RS27845 2533b181a5fd4b597db076d1943a1719 322 PANTHER PTHR40761:SF1 3 292 2.9E-18 T 16-09-2016 Spa2297_RS05380 19d88007bcfaf00fb42653c89fc80315 463 Pfam PF13529 Peptidase_C39 like family 250 401 6.3E-27 T 16-09-2016 Spa2297_RS13135 2894b66d8bd1b2cfba60111fc21300c5 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 6 86 15.991 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS13135 2894b66d8bd1b2cfba60111fc21300c5 87 PANTHER PTHR38839 1 85 1.7E-60 T 16-09-2016 Spa2297_RS13135 2894b66d8bd1b2cfba60111fc21300c5 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 16-09-2016 IPR003482 Transcription factor WhiB Spa2297_RS13135 2894b66d8bd1b2cfba60111fc21300c5 87 PANTHER PTHR38839:SF4 1 85 1.7E-60 T 16-09-2016 Spa2297_RS12055 f7e6408d1d6cc44dc92f31192040705c 281 Pfam PF01177 Asp/Glu/Hydantoin racemase 62 227 1.1E-6 T 16-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 Spa2297_RS12055 f7e6408d1d6cc44dc92f31192040705c 281 PIRSF PIRSF015736 8 247 4.7E-63 T 16-09-2016 IPR026286 Maleate isomerase/Arylmalonate decarboxylase Spa2297_RS12055 f7e6408d1d6cc44dc92f31192040705c 281 PANTHER PTHR40267 8 252 9.9E-83 T 16-09-2016 Spa2297_RS25470 6a7309b6c7550f0e3817424454743085 493 PANTHER PTHR11814 7 480 2.5E-187 T 16-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 Spa2297_RS25470 6a7309b6c7550f0e3817424454743085 493 PANTHER PTHR11814:SF123 7 480 2.5E-187 T 16-09-2016 Spa2297_RS25470 6a7309b6c7550f0e3817424454743085 493 Pfam PF00916 Sulfate permease family 10 377 2.4E-57 T 16-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Spa2297_RS00130 3df2ac44be31fd032e5ba35befa70342 241 SUPERFAMILY SSF56524 64 230 7.85E-49 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS00130 3df2ac44be31fd032e5ba35befa70342 241 Pfam PF00174 Oxidoreductase molybdopterin binding domain 72 218 5.3E-36 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS00130 3df2ac44be31fd032e5ba35befa70342 241 PANTHER PTHR19372 73 224 8.3E-46 T 16-09-2016 Spa2297_RS00130 3df2ac44be31fd032e5ba35befa70342 241 Gene3D G3DSA:3.90.420.10 70 228 2.0E-47 T 16-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Spa2297_RS04200 76cdf24cb47289c4b9a330c38a709a2b 422 PANTHER PTHR38133 1 422 9.6E-104 T 16-09-2016 Spa2297_RS04200 76cdf24cb47289c4b9a330c38a709a2b 422 PANTHER PTHR38133:SF1 1 422 9.6E-104 T 16-09-2016 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 Gene3D G3DSA:3.50.50.60 372 411 7.0E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 Gene3D G3DSA:3.50.50.60 208 278 7.0E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 Gene3D G3DSA:3.50.50.60 10 47 7.0E-32 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 SUPERFAMILY SSF51905 9 285 8.63E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 SUPERFAMILY SSF51905 370 410 8.63E-53 T 16-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 PANTHER PTHR10742:SF287 12 411 1.3E-47 T 16-09-2016 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 PANTHER PTHR10742 12 411 1.3E-47 T 16-09-2016 Spa2297_RS00790 356138e1a85e20c5c6eac2f304d1ad25 415 Pfam PF01593 Flavin containing amine oxidoreductase 18 409 2.1E-42 T 16-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spa2297_RS20970 4b140a38a9456c222e4adec793a573ee 168 Pfam PF04545 Sigma-70, region 4 102 145 1.2E-9 T 16-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20970 4b140a38a9456c222e4adec793a573ee 168 SUPERFAMILY SSF88659 102 148 4.45E-10 T 16-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS20970 4b140a38a9456c222e4adec793a573ee 168 Gene3D G3DSA:1.10.10.10 102 148 1.1E-8 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS00740 a1850cc3f5cc4c13ccf22534fccfbb19 188 Pfam PF14325 Domain of unknown function (DUF4383) 18 132 2.6E-10 T 16-09-2016 IPR025492 Protein of unknown function DUF4383 Spa2297_RS14050 df9ff85cbd1e8292490ffbe71a3b66ed 164 Pfam PF00011 Hsp20/alpha crystallin family 58 155 1.4E-23 T 16-09-2016 IPR002068 Alpha crystallin/Hsp20 domain Spa2297_RS14050 df9ff85cbd1e8292490ffbe71a3b66ed 164 Gene3D G3DSA:2.60.40.790 22 156 1.8E-35 T 16-09-2016 IPR008978 HSP20-like chaperone Spa2297_RS14050 df9ff85cbd1e8292490ffbe71a3b66ed 164 PANTHER PTHR11527 16 163 1.8E-31 T 16-09-2016 IPR031107 Small heat shock protein HSP20 Spa2297_RS14050 df9ff85cbd1e8292490ffbe71a3b66ed 164 SUPERFAMILY SSF49764 27 156 5.1E-33 T 16-09-2016 IPR008978 HSP20-like chaperone Spa2297_RS18575 1176bedea2b4c5936ff1215d68e31ee2 110 Gene3D G3DSA:3.40.30.10 32 107 1.8E-25 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS18575 1176bedea2b4c5936ff1215d68e31ee2 110 SUPERFAMILY SSF52833 28 107 4.16E-17 T 16-09-2016 IPR012336 Thioredoxin-like fold Spa2297_RS18575 1176bedea2b4c5936ff1215d68e31ee2 110 Pfam PF05768 Glutaredoxin-like domain (DUF836) 33 105 6.7E-18 T 16-09-2016 IPR008554 Glutaredoxin-like Spa2297_RS25640 d9c46f0a69e0203f3fa470a57528f6b5 361 Pfam PF06626 Protein of unknown function (DUF1152) 4 292 5.7E-49 T 16-09-2016 IPR010581 Protein of unknown function DUF1152 Spa2297_RS14355 0c8cef5d07cb4f0ceeafc38942df7fe9 141 Gene3D G3DSA:2.30.110.10 4 136 1.1E-18 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14355 0c8cef5d07cb4f0ceeafc38942df7fe9 141 SUPERFAMILY SSF50475 1 138 1.36E-20 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS14355 0c8cef5d07cb4f0ceeafc38942df7fe9 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 85 3.0E-6 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS08125 7e3e9840a5bad68e9bceddf6df612efc 282 Pfam PF13803 Domain of unknown function (DUF4184) 1 256 4.9E-50 T 16-09-2016 IPR025238 Protein of unknown function DUF4184 Spa2297_RS00935 4dff2160fbd1ecd47c9b453db7032f97 72 Pfam PF04149 Domain of unknown function (DUF397) 12 64 1.1E-15 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS11555 dd776ae192e68e5bc14563c6dcb530c1 79 SUPERFAMILY SSF55008 8 75 3.14E-14 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS11555 dd776ae192e68e5bc14563c6dcb530c1 79 Gene3D G3DSA:3.30.70.100 12 75 1.6E-17 T 16-09-2016 Spa2297_RS11555 dd776ae192e68e5bc14563c6dcb530c1 79 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 47 - T 16-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Spa2297_RS11555 dd776ae192e68e5bc14563c6dcb530c1 79 Pfam PF00403 Heavy-metal-associated domain 14 74 1.3E-11 T 16-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spa2297_RS22365 915d7b2b1eef220f310903e0075e8d49 185 PANTHER PTHR11711 38 175 5.7E-42 T 16-09-2016 Spa2297_RS22365 915d7b2b1eef220f310903e0075e8d49 185 Gene3D G3DSA:3.40.50.300 36 141 1.9E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22365 915d7b2b1eef220f310903e0075e8d49 185 PANTHER PTHR11711:SF117 38 175 5.7E-42 T 16-09-2016 Spa2297_RS22365 915d7b2b1eef220f310903e0075e8d49 185 SUPERFAMILY SSF52540 37 180 8.6E-15 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS22365 915d7b2b1eef220f310903e0075e8d49 185 Pfam PF03029 Conserved hypothetical ATP binding protein 78 181 2.7E-13 T 16-09-2016 IPR004130 GPN-loop GTPase Spa2297_RS02100 9625eb2aa7ed0d10e73c7cba574d498a 277 Pfam PF06724 Domain of Unknown Function (DUF1206) 113 181 1.2E-15 T 16-09-2016 IPR009597 Domain of unknown function DUF1206 Spa2297_RS02100 9625eb2aa7ed0d10e73c7cba574d498a 277 Pfam PF06724 Domain of Unknown Function (DUF1206) 29 96 1.2E-22 T 16-09-2016 IPR009597 Domain of unknown function DUF1206 Spa2297_RS02100 9625eb2aa7ed0d10e73c7cba574d498a 277 Pfam PF06724 Domain of Unknown Function (DUF1206) 207 275 1.3E-17 T 16-09-2016 IPR009597 Domain of unknown function DUF1206 Spa2297_RS32025 7b1d7359f6ed0095211068a11a117d86 355 Pfam PF14486 Domain of unknown function (DUF4432) 37 351 1.2E-91 T 16-09-2016 IPR027839 Protein of unknown function DUF4432 Spa2297_RS32025 7b1d7359f6ed0095211068a11a117d86 355 SUPERFAMILY SSF74650 119 352 4.39E-7 T 16-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 Spa2297_RS02070 599186edfa980c9b763da1abcd51ed88 146 SUPERFAMILY SSF55874 29 133 1.2E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02070 599186edfa980c9b763da1abcd51ed88 146 Gene3D G3DSA:3.30.565.10 22 135 7.0E-12 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02070 599186edfa980c9b763da1abcd51ed88 146 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 133 8.5E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS16760 3f043d759afb2c4d2d44cf93c87be797 490 PANTHER PTHR39441 29 489 3.4E-156 T 16-09-2016 Spa2297_RS16760 3f043d759afb2c4d2d44cf93c87be797 490 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 87 477 3.2E-134 T 16-09-2016 IPR018721 Protein of unknown function DUF2252 Spa2297_RS08795 ecf14d2648931ade714217b4c493c830 447 Pfam PF05991 YacP-like NYN domain 328 445 5.5E-17 T 16-09-2016 IPR010298 Protein of unknown function DUF901 Spa2297_RS00730 25d16d66ae773b9ee5294c045a08d8f7 412 SUPERFAMILY SSF51445 146 376 1.13E-25 T 16-09-2016 IPR017853 Glycoside hydrolase superfamily Spa2297_RS00730 25d16d66ae773b9ee5294c045a08d8f7 412 Gene3D G3DSA:3.20.20.80 158 370 1.1E-27 T 16-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 Spa2297_RS26180 83f48d09e0ade17c9ba568f1d8a3e5f0 485 Pfam PF00860 Permease family 45 437 1.2E-34 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS26180 83f48d09e0ade17c9ba568f1d8a3e5f0 485 PANTHER PTHR11119 25 465 5.0E-115 T 16-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 Spa2297_RS26180 83f48d09e0ade17c9ba568f1d8a3e5f0 485 PANTHER PTHR11119:SF9 25 465 5.0E-115 T 16-09-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 Spa2297_RS07120 0c16055366c3751682d51a7659ecac3b 168 SMART SM00507 71 120 2.3E-12 T 16-09-2016 IPR003615 HNH nuclease Spa2297_RS07120 0c16055366c3751682d51a7659ecac3b 168 PANTHER PTHR33877 1 162 3.7E-60 T 16-09-2016 Spa2297_RS07120 0c16055366c3751682d51a7659ecac3b 168 Pfam PF14279 HNH endonuclease 84 134 2.5E-10 T 16-09-2016 IPR029471 HNH endonuclease 5 Spa2297_RS04255 cbabd05244cd5874622f31d3a126287d 284 Pfam PF13569 Domain of unknown function (DUF4132) 25 202 1.6E-28 T 16-09-2016 IPR025406 Domain of unknown function DUF4132 Spa2297_RS26000 e482882cf69fb6785242cbf751b5d279 439 SUPERFAMILY SSF102114 164 411 6.28E-8 T 16-09-2016 Spa2297_RS08420 a3d31d271863572688ddfac3eca1a2ae 406 Gene3D G3DSA:3.40.50.1010 3 172 4.8E-16 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS08420 a3d31d271863572688ddfac3eca1a2ae 406 Pfam PF01936 NYN domain 32 166 5.8E-11 T 16-09-2016 IPR021139 NYN domain, limkain-b1-type Spa2297_RS29295 5e073ff1038356b1723f14fbe1c66dbb 266 PANTHER PTHR14239 3 195 2.1E-36 T 16-09-2016 Spa2297_RS29295 5e073ff1038356b1723f14fbe1c66dbb 266 SUPERFAMILY SSF51735 4 197 9.74E-34 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29295 5e073ff1038356b1723f14fbe1c66dbb 266 Gene3D G3DSA:3.40.50.720 4 194 2.7E-43 T 16-09-2016 IPR016040 NAD(P)-binding domain Spa2297_RS29295 5e073ff1038356b1723f14fbe1c66dbb 266 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 1.7E-13 T 16-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 PANTHER PTHR12526:SF355 2 386 6.6E-224 T 16-09-2016 Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 Pfam PF13439 Glycosyltransferase Family 4 15 177 2.4E-28 T 16-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 Gene3D G3DSA:3.40.50.2000 163 362 1.3E-50 T 16-09-2016 Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 384 7.7E-198 T 16-09-2016 IPR011875 Glycogen synthase, corynebacterial KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00934 Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 SUPERFAMILY SSF53756 9 385 1.73E-84 T 16-09-2016 Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 Pfam PF00534 Glycosyl transferases group 1 193 362 8.7E-32 T 16-09-2016 IPR001296 Glycosyl transferase, family 1 Spa2297_RS28845 5386d5bb85f3c0a18ea036a16c6c597a 387 PANTHER PTHR12526 2 386 6.6E-224 T 16-09-2016 Spa2297_RS10195 3793448abce7024fd3152203042ffc08 418 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 148 406 6.6E-74 T 16-09-2016 IPR024516 Mammalian cell entry, C-terminal Spa2297_RS10195 3793448abce7024fd3152203042ffc08 418 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 301 1.2E-61 T 16-09-2016 IPR005693 Virulence factor Mce protein Spa2297_RS10195 3793448abce7024fd3152203042ffc08 418 PANTHER PTHR33371 3 413 6.1E-167 T 16-09-2016 Spa2297_RS10195 3793448abce7024fd3152203042ffc08 418 PANTHER PTHR33371:SF7 3 413 6.1E-167 T 16-09-2016 Spa2297_RS10195 3793448abce7024fd3152203042ffc08 418 Pfam PF02470 MlaD protein 42 118 7.1E-13 T 16-09-2016 IPR003399 Mce/MlaD Spa2297_RS00605 eb3d2cd7da337baec82f6b277e8cdb6a 117 SUPERFAMILY SSF54593 15 113 2.15E-18 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS00605 eb3d2cd7da337baec82f6b277e8cdb6a 117 Gene3D G3DSA:3.10.180.10 10 113 1.5E-27 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS23705 525589204566c9e823094befe2bd9335 498 Gene3D G3DSA:1.25.40.10 241 459 3.8E-4 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS23705 525589204566c9e823094befe2bd9335 498 SUPERFAMILY SSF48452 419 452 3.49E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS23705 525589204566c9e823094befe2bd9335 498 SUPERFAMILY SSF48452 238 359 3.49E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS15360 59233b3e296b61bde7fed4c2cceeba44 95 Gene3D G3DSA:2.60.40.10 19 84 2.7E-6 T 16-09-2016 IPR013783 Immunoglobulin-like fold Spa2297_RS15360 59233b3e296b61bde7fed4c2cceeba44 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 5.9E-36 T 16-09-2016 IPR010814 Protein of unknown function DUF1416 Spa2297_RS01780 cf277117353b2d6c90c5afdaa4786f15 145 Gene3D G3DSA:1.20.120.620 25 122 2.0E-4 T 16-09-2016 Spa2297_RS24385 41068b3fbe1ffd7713641a7782fee8b5 317 Gene3D G3DSA:1.50.10.20 162 183 7.0E-5 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS24385 41068b3fbe1ffd7713641a7782fee8b5 317 Gene3D G3DSA:1.50.10.20 59 121 7.0E-5 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS24385 41068b3fbe1ffd7713641a7782fee8b5 317 Gene3D G3DSA:1.50.10.20 257 283 7.0E-5 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS24385 41068b3fbe1ffd7713641a7782fee8b5 317 SUPERFAMILY SSF48239 257 313 1.73E-10 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS24385 41068b3fbe1ffd7713641a7782fee8b5 317 SUPERFAMILY SSF48239 56 159 1.73E-10 T 16-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spa2297_RS15300 abda6a95d639f8d2a522f9c2c4da3cf5 97 Pfam PF04149 Domain of unknown function (DUF397) 10 27 4.5E-8 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS15300 abda6a95d639f8d2a522f9c2c4da3cf5 97 Pfam PF04149 Domain of unknown function (DUF397) 35 89 1.3E-21 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS13075 ac44282b691ed93bf83842c0068466df 307 PANTHER PTHR38480:SF1 1 307 1.7E-77 T 16-09-2016 Spa2297_RS13075 ac44282b691ed93bf83842c0068466df 307 Pfam PF06271 RDD family 18 144 2.3E-19 T 16-09-2016 IPR010432 RDD Spa2297_RS13075 ac44282b691ed93bf83842c0068466df 307 PANTHER PTHR38480 1 307 1.7E-77 T 16-09-2016 Spa2297_RS00200 74213f187162a5cdfac626676d8a7eac 110 SUPERFAMILY SSF50346 9 107 5.23E-17 T 16-09-2016 IPR011033 PRC-barrel-like Spa2297_RS02290 942dc58c19f7ff90a3a60272a8d511fc 142 SMART SM00530 51 106 6.6E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS02290 942dc58c19f7ff90a3a60272a8d511fc 142 Pfam PF01381 Helix-turn-helix 55 106 5.8E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS02290 942dc58c19f7ff90a3a60272a8d511fc 142 SUPERFAMILY SSF47413 40 110 3.56E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS02290 942dc58c19f7ff90a3a60272a8d511fc 142 Gene3D G3DSA:1.10.260.40 48 111 3.0E-11 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS20735 636a469b45a754bb4159700b60bac624 253 SUPERFAMILY SSF53474 18 214 9.91E-22 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS20735 636a469b45a754bb4159700b60bac624 253 Pfam PF12697 Alpha/beta hydrolase family 28 182 3.2E-6 T 16-09-2016 IPR000073 Alpha/beta hydrolase fold-1 Spa2297_RS20735 636a469b45a754bb4159700b60bac624 253 Gene3D G3DSA:3.40.50.1820 51 213 1.5E-16 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS01365 f08827245f625663f7373809e02bc1e7 169 Pfam PF01883 Domain of unknown function DUF59 16 73 4.2E-10 T 16-09-2016 IPR002744 Domain of unknown function DUF59 Spa2297_RS01365 f08827245f625663f7373809e02bc1e7 169 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 169 7.1E-65 T 16-09-2016 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UniPathway: UPA00930 Spa2297_RS01365 f08827245f625663f7373809e02bc1e7 169 SUPERFAMILY SSF117916 10 101 1.8E-21 T 16-09-2016 Spa2297_RS14385 c346ddd526a34ec63f78e3adeeb1e2e1 161 Pfam PF13581 Histidine kinase-like ATPase domain 7 123 1.7E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02155 a13abd1dba6ee8cf7df12084cfd30fd1 117 PANTHER PTHR36849:SF1 1 114 5.6E-52 T 16-09-2016 Spa2297_RS02155 a13abd1dba6ee8cf7df12084cfd30fd1 117 Pfam PF04343 Protein of unknown function, DUF488 5 114 4.4E-29 T 16-09-2016 IPR007438 Protein of unknown function DUF488 Spa2297_RS02155 a13abd1dba6ee8cf7df12084cfd30fd1 117 PANTHER PTHR36849 1 114 5.6E-52 T 16-09-2016 Spa2297_RS14865 c723c6225506c59832619e90be8cc4fa 325 Pfam PF16990 Carbohydrate binding module (family 35) 202 306 1.5E-7 T 16-09-2016 IPR005084 Carbohydrate binding module family 6 GO:0030246 Spa2297_RS14865 c723c6225506c59832619e90be8cc4fa 325 Gene3D G3DSA:2.60.120.260 205 323 1.7E-13 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS14865 c723c6225506c59832619e90be8cc4fa 325 SUPERFAMILY SSF49785 188 322 2.21E-13 T 16-09-2016 IPR008979 Galactose-binding domain-like Spa2297_RS17460 d6fe7a021f316bb255613fd7cef9b2fe 335 Pfam PF04893 Yip1 domain 170 326 2.6E-13 T 16-09-2016 IPR006977 Yip1 domain GO:0016020 Spa2297_RS25790 f8bc364f6714b9d969a51501d3451073 190 SUPERFAMILY SSF55729 47 171 6.15E-18 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25790 f8bc364f6714b9d969a51501d3451073 190 Gene3D G3DSA:3.40.630.30 54 172 7.3E-16 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS25790 f8bc364f6714b9d969a51501d3451073 190 Pfam PF13508 Acetyltransferase (GNAT) domain 76 166 3.1E-6 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS14580 4f6496a62752c289b2b4ed0a2f71f364 325 SUPERFAMILY SSF75011 45 265 1.83E-14 T 16-09-2016 Spa2297_RS14580 4f6496a62752c289b2b4ed0a2f71f364 325 Gene3D G3DSA:2.130.10.10 56 264 1.9E-10 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS18935 8c8080d4fea88d8ac6fdd23f05fb70cc 99 Gene3D G3DSA:1.10.287.1060 8 95 1.5E-7 T 16-09-2016 Spa2297_RS18935 8c8080d4fea88d8ac6fdd23f05fb70cc 99 SUPERFAMILY SSF140453 8 97 6.28E-9 T 16-09-2016 IPR010310 Type VII secretion system ESAT-6-like Spa2297_RS18935 8c8080d4fea88d8ac6fdd23f05fb70cc 99 Pfam PF06013 Proteins of 100 residues with WXG 7 91 5.9E-12 T 16-09-2016 IPR010310 Type VII secretion system ESAT-6-like Spa2297_RS12625 5e2fd64b16befa179d22edc4091728be 379 Pfam PF12307 Protein of unknown function (DUF3631) 173 360 1.8E-70 T 16-09-2016 IPR022081 Domain of unknown function DUF3631 Spa2297_RS32620 82e9469201e9cbf303c6270b1e6ea132 64 SUPERFAMILY SSF53686 9 64 1.92E-6 T 16-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spa2297_RS32620 82e9469201e9cbf303c6270b1e6ea132 64 Gene3D G3DSA:3.40.50.1100 17 56 7.2E-7 T 16-09-2016 Spa2297_RS03690 3114e952ee7bdccc7cbbcc24b02f5f17 500 SUPERFAMILY SSF75011 174 468 5.49E-6 T 16-09-2016 Spa2297_RS06640 1023344ff86bcbda6d5e3003795230e6 245 PANTHER PTHR37418:SF1 1 243 9.8E-114 T 16-09-2016 Spa2297_RS06640 1023344ff86bcbda6d5e3003795230e6 245 PANTHER PTHR37418 1 243 9.8E-114 T 16-09-2016 Spa2297_RS06640 1023344ff86bcbda6d5e3003795230e6 245 Gene3D G3DSA:3.20.20.70 2 233 9.0E-36 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS06640 1023344ff86bcbda6d5e3003795230e6 245 Pfam PF05853 beta-keto acid cleavage enzyme 3 232 9.4E-20 T 16-09-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 Spa2297_RS17955 58aeaae6e1b677fbffb8092c39bbccb0 112 Pfam PF07811 TadE-like protein 1 41 1.9E-6 T 16-09-2016 IPR012495 TadE-like Spa2297_RS32105 d326d1613b43457244a16ca0cf490f40 491 SUPERFAMILY SSF48208 243 388 8.96E-7 T 16-09-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 Spa2297_RS28005 35d0c2ecb2df5ce1da014fa9311d140d 233 PANTHER PTHR28511 1 231 1.6E-70 T 16-09-2016 Spa2297_RS28005 35d0c2ecb2df5ce1da014fa9311d140d 233 Pfam PF04493 Endonuclease V 28 219 5.8E-64 T 16-09-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 Spa2297_RS28005 35d0c2ecb2df5ce1da014fa9311d140d 233 Hamap MF_00801 Endonuclease V [nfi]. 15 229 32.743 T 16-09-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 Spa2297_RS28005 35d0c2ecb2df5ce1da014fa9311d140d 233 PANTHER PTHR28511:SF1 1 231 1.6E-70 T 16-09-2016 Spa2297_RS20755 bed8d43fed451a384ab2e68ff346f356 183 Pfam PF04892 VanZ like family 24 143 5.5E-16 T 16-09-2016 IPR006976 VanZ-like Spa2297_RS20755 bed8d43fed451a384ab2e68ff346f356 183 PANTHER PTHR36834 1 182 1.8E-29 T 16-09-2016 Spa2297_RS12585 a15c6c1b75706edc15f8548b771a5423 61 Pfam PF04149 Domain of unknown function (DUF397) 7 58 8.3E-23 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS19040 0cbd0c0480df344d037eaca9deaf6864 347 Pfam PF00482 Type II secretion system (T2SS), protein F 128 250 2.5E-10 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS03345 f1a8f1ee6233ac58e2a2f1701cbdc9f5 178 SUPERFAMILY SSF49695 111 177 1.71E-5 T 16-09-2016 IPR011024 Gamma-crystallin-related Spa2297_RS03345 f1a8f1ee6233ac58e2a2f1701cbdc9f5 178 Gene3D G3DSA:2.60.20.10 71 177 1.3E-9 T 16-09-2016 Spa2297_RS06595 7df8938533222ff14e68a2208e07a2c4 105 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 8 42 6.0E-10 T 16-09-2016 IPR020264 Uncharacterised protein family YidG Spa2297_RS06595 7df8938533222ff14e68a2208e07a2c4 105 Pfam PF02656 Domain of unknown function (DUF202) 8 69 2.0E-12 T 16-09-2016 IPR003807 Domain of unknown function DUF202 Spa2297_RS22455 8b77502ea4e818f3f5e279544812754f 159 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 135 4.5E-14 T 16-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain Spa2297_RS22455 8b77502ea4e818f3f5e279544812754f 159 Gene3D G3DSA:3.30.530.20 4 149 2.4E-21 T 16-09-2016 IPR023393 START-like domain Spa2297_RS22455 8b77502ea4e818f3f5e279544812754f 159 SUPERFAMILY SSF55961 1 151 2.49E-40 T 16-09-2016 Spa2297_RS23630 fa21033191991018ba21395f8fbd7e64 372 Gene3D G3DSA:1.20.5.620 60 115 5.5E-4 T 16-09-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain Spa2297_RS27600 24490f53c8008294a30a016dd7a404ea 178 PANTHER PTHR13947 19 153 3.6E-20 T 16-09-2016 Spa2297_RS27600 24490f53c8008294a30a016dd7a404ea 178 Pfam PF00583 Acetyltransferase (GNAT) family 66 153 3.7E-12 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS27600 24490f53c8008294a30a016dd7a404ea 178 Gene3D G3DSA:3.40.630.30 3 153 5.5E-24 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS27600 24490f53c8008294a30a016dd7a404ea 178 SUPERFAMILY SSF55729 7 169 7.62E-25 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS16860 61b9494256602f1dc9a8b80ddec50c4f 179 Pfam PF10759 Protein of unknown function (DUF2587) 31 166 8.2E-77 T 16-09-2016 IPR019695 Bacterial proteasome activator GO:0061136 Spa2297_RS31795 e8fa0a16d95bd6d95d46ab950dd43108 507 Pfam PF02706 Chain length determinant protein 16 139 2.3E-10 T 16-09-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 Spa2297_RS10695 2e03049c34e3f6e23214bd350ba62447 117 SUPERFAMILY SSF53927 12 111 9.4E-11 T 16-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 Spa2297_RS10695 2e03049c34e3f6e23214bd350ba62447 117 Gene3D G3DSA:3.40.140.10 14 83 3.7E-7 T 16-09-2016 Spa2297_RS33745 0b53fe16aee8c4e104c896094be79fc4 80 PANTHER PTHR24423 12 80 7.9E-15 T 16-09-2016 Spa2297_RS33745 0b53fe16aee8c4e104c896094be79fc4 80 PANTHER PTHR24423:SF555 12 80 7.9E-15 T 16-09-2016 Spa2297_RS21115 d84464d351fae965e433e4c2406c282a 349 PANTHER PTHR10584 1 343 9.0E-111 T 16-09-2016 Spa2297_RS21115 d84464d351fae965e433e4c2406c282a 349 SUPERFAMILY SSF53613 15 312 1.87E-67 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS21115 d84464d351fae965e433e4c2406c282a 349 Pfam PF00294 pfkB family carbohydrate kinase 16 307 2.2E-45 T 16-09-2016 IPR011611 Carbohydrate kinase PfkB Spa2297_RS21115 d84464d351fae965e433e4c2406c282a 349 Gene3D G3DSA:3.40.1190.20 12 319 7.1E-97 T 16-09-2016 IPR029056 Ribokinase-like Spa2297_RS21115 d84464d351fae965e433e4c2406c282a 349 PANTHER PTHR10584:SF186 1 343 9.0E-111 T 16-09-2016 Spa2297_RS27965 c179ec2ad008e8fffe7597524e5e3922 258 SUPERFAMILY SSF55909 3 254 1.37E-53 T 16-09-2016 Spa2297_RS27965 c179ec2ad008e8fffe7597524e5e3922 258 Pfam PF02274 Amidinotransferase 28 148 4.7E-10 T 16-09-2016 Spa2297_RS27965 c179ec2ad008e8fffe7597524e5e3922 258 PANTHER PTHR12737:SF9 1 257 1.5E-74 T 16-09-2016 Spa2297_RS27965 c179ec2ad008e8fffe7597524e5e3922 258 Gene3D G3DSA:3.75.10.10 4 253 7.1E-66 T 16-09-2016 Spa2297_RS27965 c179ec2ad008e8fffe7597524e5e3922 258 PANTHER PTHR12737 1 257 1.5E-74 T 16-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 Spa2297_RS27920 c3c8c3dd18188fc7e9ae5e7d4402e61a 346 SUPERFAMILY SSF56747 130 197 4.58E-5 T 16-09-2016 Spa2297_RS27920 c3c8c3dd18188fc7e9ae5e7d4402e61a 346 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 259 2.2E-71 T 16-09-2016 IPR014145 DNA ligase D, polymerase domain Spa2297_RS27920 c3c8c3dd18188fc7e9ae5e7d4402e61a 346 Pfam PF01896 DNA primase small subunit 135 256 9.5E-10 T 16-09-2016 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Spa2297_RS27920 c3c8c3dd18188fc7e9ae5e7d4402e61a 346 PANTHER PTHR10459:SF36 47 341 1.1E-182 T 16-09-2016 Spa2297_RS27920 c3c8c3dd18188fc7e9ae5e7d4402e61a 346 PANTHER PTHR10459 47 341 1.1E-182 T 16-09-2016 Spa2297_RS09360 eecb7dd35f94288b7770ed80596492dc 221 Pfam PF11303 Protein of unknown function (DUF3105) 91 213 1.4E-43 T 16-09-2016 IPR021454 Protein of unknown function DUF3105 Spa2297_RS27260 8b17526bbf453d808e5dccb77f4d9bc4 308 Pfam PF13649 Methyltransferase domain 68 165 1.7E-9 T 16-09-2016 Spa2297_RS27260 8b17526bbf453d808e5dccb77f4d9bc4 308 Gene3D G3DSA:3.40.50.150 48 236 5.3E-23 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27260 8b17526bbf453d808e5dccb77f4d9bc4 308 PANTHER PTHR10108:SF855 52 169 2.6E-14 T 16-09-2016 Spa2297_RS27260 8b17526bbf453d808e5dccb77f4d9bc4 308 SUPERFAMILY SSF53335 33 235 4.6E-29 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS27260 8b17526bbf453d808e5dccb77f4d9bc4 308 PANTHER PTHR10108 52 169 2.6E-14 T 16-09-2016 Spa2297_RS00385 1e2fb5247063cfb2daed07650074919a 276 Gene3D G3DSA:3.90.1200.10 112 218 5.6E-10 T 16-09-2016 Spa2297_RS00385 1e2fb5247063cfb2daed07650074919a 276 SUPERFAMILY SSF56112 44 254 5.83E-27 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS00385 1e2fb5247063cfb2daed07650074919a 276 Pfam PF01636 Phosphotransferase enzyme family 45 220 2.8E-15 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 SMART SM00530 18 73 8.3E-11 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 Pfam PF13560 Helix-turn-helix domain 16 76 2.2E-13 T 16-09-2016 Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 PANTHER PTHR10245 14 196 1.4E-73 T 16-09-2016 Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 Gene3D G3DSA:1.10.260.40 16 72 1.8E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 PANTHER PTHR10245:SF17 14 196 1.4E-73 T 16-09-2016 Spa2297_RS27240 1f50f9bd2049a1b733072d2597c2392d 275 SUPERFAMILY SSF47413 10 72 1.21E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS18365 bd866fb11f6f3b2c66b6c563688684c3 134 SUPERFAMILY SSF55874 26 112 3.18E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18365 bd866fb11f6f3b2c66b6c563688684c3 134 Pfam PF13581 Histidine kinase-like ATPase domain 6 112 8.7E-10 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS18365 bd866fb11f6f3b2c66b6c563688684c3 134 Gene3D G3DSA:3.30.565.10 26 112 4.8E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS13735 7000e3e95814fcebee8d495f2620aac9 125 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 27 119 3.8E-27 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS08030 0ae60b1f6539e34b7fcc3c8b10a061c9 229 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 227 2.1E-87 T 16-09-2016 IPR010296 Protein of unknown function DUF899, thioredoxin-like Spa2297_RS12670 301fd3226223411bff43b4dd9e8f3f7d 300 Pfam PF10935 Protein of unknown function (DUF2637) 12 92 2.1E-8 T 16-09-2016 IPR021235 Protein of unknown function DUF2637 Spa2297_RS01815 93a43c41983dab58862cadb283583acb 243 SUPERFAMILY SSF81301 44 179 1.11E-16 T 16-09-2016 Spa2297_RS01815 93a43c41983dab58862cadb283583acb 243 Pfam PF14907 Uncharacterised nucleotidyltransferase 43 215 7.9E-8 T 16-09-2016 Spa2297_RS19115 7118e4fa8149da1dc3c57e6e69ed2d6b 63 Pfam PF04149 Domain of unknown function (DUF397) 6 59 1.6E-19 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS17540 cfcd21c65781b43dcaffdd9e49c99285 178 Pfam PF10722 Putative bacterial sensory transduction regulator 31 156 1.3E-17 T 16-09-2016 IPR019660 Putative sensory transduction regulator YbjN Spa2297_RS15705 c067dea82ad62f2afa513727025d1256 523 PANTHER PTHR31302:SF7 186 442 1.3E-49 T 16-09-2016 Spa2297_RS15705 c067dea82ad62f2afa513727025d1256 523 Pfam PF00149 Calcineurin-like phosphoesterase 267 434 7.1E-13 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS15705 c067dea82ad62f2afa513727025d1256 523 SUPERFAMILY SSF56300 266 479 8.65E-27 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS15705 c067dea82ad62f2afa513727025d1256 523 PANTHER PTHR31302 186 442 1.3E-49 T 16-09-2016 Spa2297_RS15705 c067dea82ad62f2afa513727025d1256 523 Gene3D G3DSA:3.60.21.10 266 455 2.4E-19 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS29735 b9517c09ff4137e9d72d1f6297e26ba0 164 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 162 1.1E-62 T 16-09-2016 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 SUPERFAMILY SSF81923 81 179 1.44E-10 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 Gene3D G3DSA:1.10.1780.10 1 45 4.8E-39 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 Gene3D G3DSA:1.10.1780.10 80 180 4.8E-39 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 SUPERFAMILY SSF81923 3 55 3.66E-8 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 133 178 1.9E-6 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS22285 19c27b61597e1470cefe91ea608addf7 192 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 54 0.0058 T 16-09-2016 IPR004176 Clp, N-terminal GO:0019538 Spa2297_RS10245 c75b52eb8e71f161769bd50b22e14f93 217 PANTHER PTHR38847 10 216 3.5E-166 T 16-09-2016 Spa2297_RS10245 c75b52eb8e71f161769bd50b22e14f93 217 Pfam PF14273 Domain of unknown function (DUF4360) 36 214 6.9E-70 T 16-09-2016 IPR025649 Protein of unknown function DUF4360 Spa2297_RS10245 c75b52eb8e71f161769bd50b22e14f93 217 PANTHER PTHR38847:SF2 10 216 3.5E-166 T 16-09-2016 Spa2297_RS24890 fa91675b4236b72d5f428f9de76771f3 264 Pfam PF11361 Protein of unknown function (DUF3159) 28 213 2.4E-55 T 16-09-2016 IPR016566 Uncharacterised conserved protein UCP010219 Spa2297_RS24890 fa91675b4236b72d5f428f9de76771f3 264 PIRSF PIRSF010219 1 228 9.1E-86 T 16-09-2016 IPR016566 Uncharacterised conserved protein UCP010219 Spa2297_RS19060 cede964251eac739cabd81ea54d9299f 145 Pfam PF07811 TadE-like protein 20 62 4.4E-9 T 16-09-2016 IPR012495 TadE-like Spa2297_RS07675 89f4caff1394ade360014e40203260b3 63 Pfam PF05122 Mobile element transfer protein 12 61 3.2E-30 T 16-09-2016 IPR007806 Mobile element transfer Spa2297_RS15770 59a905b7da3df873db90055d7ea898b0 262 PANTHER PTHR35535 15 260 3.1E-91 T 16-09-2016 Spa2297_RS15770 59a905b7da3df873db90055d7ea898b0 262 PANTHER PTHR35535:SF2 15 260 3.1E-91 T 16-09-2016 Spa2297_RS15770 59a905b7da3df873db90055d7ea898b0 262 Pfam PF03724 META domain 157 256 3.7E-25 T 16-09-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ Spa2297_RS15770 59a905b7da3df873db90055d7ea898b0 262 Pfam PF03724 META domain 44 149 7.0E-22 T 16-09-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ Spa2297_RS13540 8740ab94876ee1329514200eead969ad 164 Pfam PF14433 SUKH-3 immunity protein 11 155 2.9E-50 T 16-09-2016 IPR025850 SUKH-3 immunity protein Spa2297_RS11025 5298ab11ac2b31ef9f4c255f544002b5 223 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 156 6.6E-20 T 16-09-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Spa2297_RS11025 5298ab11ac2b31ef9f4c255f544002b5 223 Pfam PF04093 rod shape-determining protein MreD 3 153 3.1E-6 T 16-09-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Spa2297_RS15950 c6ac483325aa7bd10787019464372b4a 180 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 178 3.1E-26 T 16-09-2016 IPR023869 tRNA adenosine deaminase-associated protein, putative Spa2297_RS01415 f59f5885b2381bc95e655a60f643d2ff 125 Pfam PF05331 Protein of unknown function (DUF742) 10 123 1.5E-36 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS01415 f59f5885b2381bc95e655a60f643d2ff 125 PANTHER PTHR36221 1 123 4.5E-36 T 16-09-2016 Spa2297_RS00095 d04c88f01c781afcdad8aa0f51786280 711 Pfam PF13515 Fusaric acid resistance protein-like 391 513 1.4E-7 T 16-09-2016 Spa2297_RS02800 8cf98f46dfaaf3590df7e9242a6c2444 269 PANTHER PTHR30294 23 263 1.3E-18 T 16-09-2016 Spa2297_RS02800 8cf98f46dfaaf3590df7e9242a6c2444 269 PIRSF PIRSF006648 1 267 1.8E-39 T 16-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 Spa2297_RS02800 8cf98f46dfaaf3590df7e9242a6c2444 269 Pfam PF01061 ABC-2 type transporter 35 230 6.8E-15 T 16-09-2016 IPR013525 ABC-2 type transporter GO:0016020 Spa2297_RS26870 766f606b73f0adfbd31190592d53fd33 238 PANTHER PTHR24220 3 211 9.8E-57 T 16-09-2016 Spa2297_RS26870 766f606b73f0adfbd31190592d53fd33 238 SUPERFAMILY SSF52540 2 211 3.96E-46 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26870 766f606b73f0adfbd31190592d53fd33 238 SMART SM00382 27 217 5.5E-11 T 16-09-2016 IPR003593 AAA+ ATPase domain Spa2297_RS26870 766f606b73f0adfbd31190592d53fd33 238 Gene3D G3DSA:3.40.50.300 1 211 5.4E-53 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS26870 766f606b73f0adfbd31190592d53fd33 238 Pfam PF00005 ABC transporter 19 168 2.2E-25 T 16-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spa2297_RS28995 27ebca009d3cc6ddc6a66d49f2a9b289 315 Pfam PF03640 Secreted repeat of unknown function 142 182 4.1E-15 T 16-09-2016 IPR005297 Lipoprotein repeat Spa2297_RS28995 27ebca009d3cc6ddc6a66d49f2a9b289 315 Pfam PF03640 Secreted repeat of unknown function 263 304 4.2E-14 T 16-09-2016 IPR005297 Lipoprotein repeat Spa2297_RS28995 27ebca009d3cc6ddc6a66d49f2a9b289 315 Pfam PF03640 Secreted repeat of unknown function 80 123 5.7E-14 T 16-09-2016 IPR005297 Lipoprotein repeat Spa2297_RS28995 27ebca009d3cc6ddc6a66d49f2a9b289 315 Pfam PF03640 Secreted repeat of unknown function 203 244 1.2E-15 T 16-09-2016 IPR005297 Lipoprotein repeat Spa2297_RS28995 27ebca009d3cc6ddc6a66d49f2a9b289 315 PANTHER PTHR39335 1 315 7.8E-112 T 16-09-2016 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 SUPERFAMILY SSF111337 7 346 3.4E-71 T 16-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 PANTHER PTHR30307:SF0 6 347 3.4E-113 T 16-09-2016 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 Pfam PF02547 Queuosine biosynthesis protein 7 345 4.3E-73 T 16-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 PANTHER PTHR30307 6 347 3.4E-113 T 16-09-2016 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 Gene3D G3DSA:3.40.1780.10 7 63 5.3E-65 T 16-09-2016 Spa2297_RS07165 46f90ed7c019fb5bc1f0ff99d9fbb22d 347 Gene3D G3DSA:3.40.1780.10 190 346 5.3E-65 T 16-09-2016 Spa2297_RS27095 5cc798e583925b9e03ef76575ce1423a 262 PANTHER PTHR36852 1 249 2.4E-126 T 16-09-2016 Spa2297_RS27095 5cc798e583925b9e03ef76575ce1423a 262 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 5 249 1.7E-65 T 16-09-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 Spa2297_RS27095 5cc798e583925b9e03ef76575ce1423a 262 PANTHER PTHR36852:SF2 1 249 2.4E-126 T 16-09-2016 Spa2297_RS18800 9405476d51ad9678853fbdee38af2fcc 256 PANTHER PTHR31272:SF4 8 247 1.2E-94 T 16-09-2016 Spa2297_RS18800 9405476d51ad9678853fbdee38af2fcc 256 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 28 235 2.5E-51 T 16-09-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Spa2297_RS18800 9405476d51ad9678853fbdee38af2fcc 256 PANTHER PTHR31272 8 247 1.2E-94 T 16-09-2016 Spa2297_RS20885 bc0d234d599111d5835e34aafb049cf3 101 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 64 93 0.0024 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS31730 84db0e523b2fe1559dbd516481980bda 315 Gene3D G3DSA:3.90.550.10 5 217 3.6E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS31730 84db0e523b2fe1559dbd516481980bda 315 Pfam PF00535 Glycosyl transferase family 2 8 120 1.9E-27 T 16-09-2016 IPR001173 Glycosyltransferase 2-like Spa2297_RS31730 84db0e523b2fe1559dbd516481980bda 315 PANTHER PTHR22916 1 308 3.3E-178 T 16-09-2016 Spa2297_RS31730 84db0e523b2fe1559dbd516481980bda 315 SUPERFAMILY SSF53448 5 218 1.22E-43 T 16-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases Spa2297_RS31730 84db0e523b2fe1559dbd516481980bda 315 PANTHER PTHR22916:SF12 1 308 3.3E-178 T 16-09-2016 Spa2297_RS10000 d9c67dc38432dc1888cb4de38cfed24b 287 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 1.2E-16 T 16-09-2016 IPR027860 Domain of unknown function DUF4429 Spa2297_RS10000 d9c67dc38432dc1888cb4de38cfed24b 287 Pfam PF14472 Domain of unknown function (DUF4429) 140 229 3.0E-39 T 16-09-2016 IPR027860 Domain of unknown function DUF4429 Spa2297_RS10000 d9c67dc38432dc1888cb4de38cfed24b 287 Pfam PF09851 Short C-terminal domain 257 284 1.2E-6 T 16-09-2016 IPR018649 SHOCT domain Spa2297_RS22080 3f6fb8cce67f685e649f61aba8bd1c7e 326 SUPERFAMILY SSF48452 19 110 1.52E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS22080 3f6fb8cce67f685e649f61aba8bd1c7e 326 Gene3D G3DSA:1.25.40.10 21 110 1.2E-10 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS02755 4f1540208f3d57af52bb51cf75e469f8 76 Pfam PF01320 Colicin immunity protein / pyocin immunity protein 7 67 5.5E-5 T 16-09-2016 IPR023802 Colicin/pyocin immunity protein domain GO:0015643 Spa2297_RS02755 4f1540208f3d57af52bb51cf75e469f8 76 Gene3D G3DSA:1.10.1200.20 5 74 6.8E-10 T 16-09-2016 IPR023802 Colicin/pyocin immunity protein domain GO:0015643 Spa2297_RS06795 4b529bf41c870c612c96a85117fce50e 244 Gene3D G3DSA:3.20.20.410 2 238 2.6E-73 T 16-09-2016 IPR002763 Protein of unknown function DUF72 Spa2297_RS06795 4b529bf41c870c612c96a85117fce50e 244 Pfam PF01904 Protein of unknown function DUF72 20 237 5.2E-57 T 16-09-2016 IPR002763 Protein of unknown function DUF72 Spa2297_RS06795 4b529bf41c870c612c96a85117fce50e 244 PANTHER PTHR30348 1 238 9.9E-73 T 16-09-2016 Spa2297_RS06795 4b529bf41c870c612c96a85117fce50e 244 SUPERFAMILY SSF117396 1 238 1.07E-73 T 16-09-2016 IPR002763 Protein of unknown function DUF72 Spa2297_RS19380 52af7669b9716b4948885859c5dee774 297 Pfam PF12679 ABC-2 family transporter protein 94 241 2.0E-9 T 16-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 Spa2297_RS10595 f45f93943f4ae419282e82645c8735e0 240 SUPERFAMILY SSF53474 114 239 2.08E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10595 f45f93943f4ae419282e82645c8735e0 240 SUPERFAMILY SSF53474 21 85 2.08E-19 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS10595 f45f93943f4ae419282e82645c8735e0 240 Gene3D G3DSA:3.40.50.1820 21 240 4.5E-20 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS13030 5935a6d24ba00235d2102aaef6be58b0 231 Pfam PF13559 Domain of unknown function (DUF4129) 132 201 5.7E-16 T 16-09-2016 IPR025403 Domain of unknown function DUF4129 Spa2297_RS19110 6ec1950c86cda850162793f0ac94e8a0 530 SUPERFAMILY SSF158414 20 82 7.32E-5 T 16-09-2016 IPR029013 HP0062-like domain Spa2297_RS21175 1dbad5f50c494d7bc2e83075c815f817 128 Pfam PF07811 TadE-like protein 21 63 1.2E-7 T 16-09-2016 IPR012495 TadE-like Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 Gene3D G3DSA:3.90.1720.10 102 200 9.9E-12 T 16-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 SUPERFAMILY SSF47090 347 420 1.18E-10 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 SUPERFAMILY SSF47090 251 324 2.82E-5 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 Gene3D G3DSA:1.10.101.10 351 419 1.5E-10 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 Gene3D G3DSA:1.10.101.10 256 324 1.5E-4 T 16-09-2016 IPR002477 Peptidoglycan binding-like Spa2297_RS12115 8f682ea28ab5091c95064a5c9d46d409 421 SUPERFAMILY SSF54001 100 197 3.27E-8 T 16-09-2016 Spa2297_RS15155 c9dcbd56a3862d732be4187ede7bb3a2 147 SUPERFAMILY SSF102462 13 147 5.23E-45 T 16-09-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 Spa2297_RS15155 c9dcbd56a3862d732be4187ede7bb3a2 147 Gene3D G3DSA:3.40.1490.10 13 147 5.0E-65 T 16-09-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 Spa2297_RS15155 c9dcbd56a3862d732be4187ede7bb3a2 147 Pfam PF09391 Protein of unknown function (DUF2000) 16 146 1.1E-43 T 16-09-2016 IPR018988 Protein of unknown function DUF2000 Spa2297_RS16455 aa77b961e6ab9f2dafe699365458bbbc 343 Pfam PF01168 Alanine racemase, N-terminal domain 7 153 8.4E-14 T 16-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 Spa2297_RS16455 aa77b961e6ab9f2dafe699365458bbbc 343 SUPERFAMILY SSF51419 9 176 3.36E-15 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS16455 aa77b961e6ab9f2dafe699365458bbbc 343 Gene3D G3DSA:3.20.20.10 26 172 3.4E-13 T 16-09-2016 IPR029066 PLP-binding barrel Spa2297_RS29835 efa22e2fd4b0f739df72c97d4943e816 343 Gene3D G3DSA:1.10.600.10 3 315 3.7E-80 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS29835 efa22e2fd4b0f739df72c97d4943e816 343 SUPERFAMILY SSF48576 4 316 8.63E-59 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS28840 9fda26c682ccef26699068e00efd9cf5 258 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 222 241 1.4E-7 T 16-09-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 Spa2297_RS28840 9fda26c682ccef26699068e00efd9cf5 258 Pfam PF06276 Ferric iron reductase FhuF-like transporter 123 207 5.5E-6 T 16-09-2016 IPR022770 Ferric iron reductase FhuF domain Spa2297_RS25410 c583dc5794e3f326a25af309e68eb720 313 Pfam PF14257 Domain of unknown function (DUF4349) 25 284 1.5E-77 T 16-09-2016 IPR025645 Domain of unknown function DUF4349 Spa2297_RS08955 819652ebfc88315c4c7a5e2b0815a612 181 Pfam PF11241 Protein of unknown function (DUF3043) 13 179 5.0E-64 T 16-09-2016 IPR021403 Protein of unknown function DUF3043 Spa2297_RS00435 042627f8c0691c5aae99936fe8fd6e42 264 PIRSF PIRSF017393 2 264 1.0E-88 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS00435 042627f8c0691c5aae99936fe8fd6e42 264 SUPERFAMILY SSF53335 12 242 1.95E-44 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00435 042627f8c0691c5aae99936fe8fd6e42 264 Gene3D G3DSA:3.40.50.150 5 263 1.1E-100 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00435 042627f8c0691c5aae99936fe8fd6e42 264 Pfam PF04672 S-adenosyl methyltransferase 4 263 4.2E-104 T 16-09-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type Spa2297_RS31855 e78074e522af9da89fefc6a6f310bca6 73 Pfam PF11272 Protein of unknown function (DUF3072) 8 59 3.0E-24 T 16-09-2016 IPR021425 Protein of unknown function DUF3072 Spa2297_RS22190 409a04f026bc08bdab307770c7ff6991 137 PANTHER PTHR35526 1 137 1.3E-40 T 16-09-2016 Spa2297_RS22190 409a04f026bc08bdab307770c7ff6991 137 PANTHER PTHR35526:SF1 1 137 1.3E-40 T 16-09-2016 Spa2297_RS05825 d1ce2890cb5ec23e2846059178444126 188 Pfam PF14280 Domain of unknown function (DUF4365) 34 181 9.8E-25 T 16-09-2016 IPR025375 Domain of unknown function DUF4365 Spa2297_RS03995 99e0cf979118ba8f8a37d3d78d6c0820 193 PANTHER PTHR42305 1 193 5.7E-55 T 16-09-2016 Spa2297_RS30610 abe2705e17f9d4453676b9b7bf16ebf1 264 Pfam PF03965 Penicillinase repressor 186 252 7.6E-5 T 16-09-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 Spa2297_RS30610 abe2705e17f9d4453676b9b7bf16ebf1 264 Gene3D G3DSA:1.10.10.10 186 246 1.2E-5 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS02090 b863fbcae36e0bcf6d4df1f091441043 748 Pfam PF04632 Fusaric acid resistance protein family 420 691 2.4E-17 T 16-09-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 Spa2297_RS23110 1f0b705215cdeb077576bc99ab4761a3 1211 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 33 229 9.0E-4 T 16-09-2016 Spa2297_RS05615 b9aeb4af6ce3911d32ff0fce091a62c3 167 SUPERFAMILY SSF47413 4 74 4.74E-9 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS05615 b9aeb4af6ce3911d32ff0fce091a62c3 167 Gene3D G3DSA:1.10.260.40 3 75 4.7E-12 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS05615 b9aeb4af6ce3911d32ff0fce091a62c3 167 Pfam PF01381 Helix-turn-helix 13 69 1.3E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS05615 b9aeb4af6ce3911d32ff0fce091a62c3 167 SMART SM00530 12 69 2.1E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS04060 8d0178b85e814798dae2cb0f3a9a9573 140 PANTHER PTHR30615 3 140 5.5E-39 T 16-09-2016 Spa2297_RS04060 8d0178b85e814798dae2cb0f3a9a9573 140 PIRSF PIRSF004681 4 140 2.2E-28 T 16-09-2016 IPR001602 Uncharacterised protein family UPF0047 Spa2297_RS04060 8d0178b85e814798dae2cb0f3a9a9573 140 Pfam PF01894 Uncharacterised protein family UPF0047 22 136 6.1E-24 T 16-09-2016 IPR001602 Uncharacterised protein family UPF0047 Spa2297_RS04060 8d0178b85e814798dae2cb0f3a9a9573 140 Gene3D G3DSA:2.60.120.460 6 140 7.4E-32 T 16-09-2016 IPR001602 Uncharacterised protein family UPF0047 Spa2297_RS04060 8d0178b85e814798dae2cb0f3a9a9573 140 SUPERFAMILY SSF111038 6 140 4.58E-32 T 16-09-2016 IPR001602 Uncharacterised protein family UPF0047 Spa2297_RS00465 e5fcb61a385174528af41b10d9eb9ea8 291 PANTHER PTHR10108 83 277 4.9E-16 T 16-09-2016 Spa2297_RS00465 e5fcb61a385174528af41b10d9eb9ea8 291 SUPERFAMILY SSF53335 18 288 7.41E-30 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00465 e5fcb61a385174528af41b10d9eb9ea8 291 Pfam PF08241 Methyltransferase domain 101 197 3.2E-9 T 16-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 Spa2297_RS00465 e5fcb61a385174528af41b10d9eb9ea8 291 Gene3D G3DSA:3.40.50.150 16 274 8.4E-32 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS15530 72b3c6c3ae539a7cdb44931b93788516 445 PANTHER PTHR22574:SF14 247 443 6.1E-61 T 16-09-2016 Spa2297_RS15530 72b3c6c3ae539a7cdb44931b93788516 445 PANTHER PTHR22574 247 443 6.1E-61 T 16-09-2016 Spa2297_RS29560 3c259320a9388e87a5dc84754c50f714 269 Pfam PF13649 Methyltransferase domain 103 202 1.9E-11 T 16-09-2016 Spa2297_RS29560 3c259320a9388e87a5dc84754c50f714 269 SUPERFAMILY SSF53335 89 248 2.54E-20 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS29560 3c259320a9388e87a5dc84754c50f714 269 Gene3D G3DSA:3.40.50.150 88 250 9.4E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS00950 dd9da0041f12ea3937fcaf410b267c36 397 PANTHER PTHR38165 1 397 1.1E-254 T 16-09-2016 Spa2297_RS00950 dd9da0041f12ea3937fcaf410b267c36 397 PANTHER PTHR38165:SF2 1 397 1.1E-254 T 16-09-2016 Spa2297_RS00950 dd9da0041f12ea3937fcaf410b267c36 397 Pfam PF16483 Beta-1,3-glucanase 36 393 1.4E-104 T 16-09-2016 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 Spa2297_RS18350 efa51cdb5b4648dcc45f4ab6b4d24399 225 PANTHER PTHR21666 89 224 2.0E-38 T 16-09-2016 Spa2297_RS18350 efa51cdb5b4648dcc45f4ab6b4d24399 225 Gene3D G3DSA:2.70.70.10 63 219 5.6E-45 T 16-09-2016 Spa2297_RS18350 efa51cdb5b4648dcc45f4ab6b4d24399 225 SUPERFAMILY SSF51261 65 218 2.22E-45 T 16-09-2016 IPR011055 Duplicated hybrid motif Spa2297_RS18350 efa51cdb5b4648dcc45f4ab6b4d24399 225 Pfam PF01551 Peptidase family M23 112 214 1.1E-30 T 16-09-2016 IPR016047 Peptidase M23 Spa2297_RS03670 53471e325c4089effd773eb8e2465406 181 Pfam PF17197 Domain of unknown function (DUF5134) 33 181 5.1E-35 T 16-09-2016 IPR033458 Protein of unknown function DUF5134 Spa2297_RS02240 6c234ea0a54a363fe54f5a8b8f4d5d74 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 126 2.4E-26 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS10975 ffe16768b539cb4095284cf2a096b888 258 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 194 4.7E-48 T 16-09-2016 IPR018768 Domain of unknown function DUF2344 Spa2297_RS10975 ffe16768b539cb4095284cf2a096b888 258 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 218 2.5E-53 T 16-09-2016 IPR018768 Domain of unknown function DUF2344 Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 201 1.0E-5 T 16-09-2016 IPR000014 PAS domain Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 SUPERFAMILY SSF55785 91 194 6.46E-11 T 16-09-2016 IPR000014 PAS domain Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 Pfam PF08447 PAS fold 104 186 1.3E-9 T 16-09-2016 IPR013655 PAS fold-3 GO:0005515 Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 Gene3D G3DSA:3.30.450.20 90 194 1.4E-12 T 16-09-2016 Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 276 371 6.8E-9 T 16-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 Spa2297_RS02415 b4fb0bffef59916408d99b8c3e29188c 442 SMART SM00086 154 196 0.0028 T 16-09-2016 IPR001610 PAC motif Spa2297_RS22200 dc66f64181d17d5fb58dce52ba7df883 530 PANTHER PTHR10110:SF86 21 461 6.5E-107 T 16-09-2016 Spa2297_RS22200 dc66f64181d17d5fb58dce52ba7df883 530 PANTHER PTHR10110 21 461 6.5E-107 T 16-09-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 Spa2297_RS22200 dc66f64181d17d5fb58dce52ba7df883 530 Pfam PF00999 Sodium/hydrogen exchanger family 8 402 2.7E-60 T 16-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spa2297_RS22200 dc66f64181d17d5fb58dce52ba7df883 530 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 523 3.0E-104 T 16-09-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 Spa2297_RS11525 e8e8ee6f60f175e2353c57558cf56444 293 Pfam PF12679 ABC-2 family transporter protein 31 291 2.4E-10 T 16-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 Spa2297_RS24945 f9ab6518a773fdbd2de7c43e03477eef 250 Pfam PF13676 TIR domain 4 122 3.1E-14 T 16-09-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 Spa2297_RS24945 f9ab6518a773fdbd2de7c43e03477eef 250 SUPERFAMILY SSF52200 3 102 6.02E-8 T 16-09-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 Spa2297_RS24945 f9ab6518a773fdbd2de7c43e03477eef 250 Gene3D G3DSA:3.40.50.10140 4 106 6.7E-4 T 16-09-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 Spa2297_RS29015 c2c0ad4c778c71f394ee72200f815d25 223 SUPERFAMILY SSF81343 4 222 2.45E-52 T 16-09-2016 Spa2297_RS29015 c2c0ad4c778c71f394ee72200f815d25 223 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 8 222 9.6E-79 T 16-09-2016 IPR011138 Succinate dehydrogenase cytochrome b558 subunit UniPathway: UPA00223 Spa2297_RS29015 c2c0ad4c778c71f394ee72200f815d25 223 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 108 208 1.9E-6 T 16-09-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 Spa2297_RS29015 c2c0ad4c778c71f394ee72200f815d25 223 Gene3D G3DSA:1.20.950.10 16 215 3.1E-14 T 16-09-2016 Spa2297_RS01205 8287afb4507202b66a6554d87966af35 280 PANTHER PTHR11907 1 276 6.1E-95 T 16-09-2016 Spa2297_RS01205 8287afb4507202b66a6554d87966af35 280 PANTHER PTHR11907:SF1 1 276 6.1E-95 T 16-09-2016 Spa2297_RS01205 8287afb4507202b66a6554d87966af35 280 Gene3D G3DSA:3.60.20.10 1 267 5.4E-63 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS01205 8287afb4507202b66a6554d87966af35 280 SUPERFAMILY SSF56235 2 266 2.14E-30 T 16-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal Spa2297_RS01205 8287afb4507202b66a6554d87966af35 280 Pfam PF13230 Glutamine amidotransferases class-II 29 263 1.8E-15 T 16-09-2016 IPR026869 Putative glutamine amidotransferase type 2 Spa2297_RS17950 c34ba5cda314e9569c5d1f0a19c51530 75 Pfam PF14029 Protein of unknown function (DUF4244) 22 72 3.4E-24 T 16-09-2016 IPR025338 Protein of unknown function DUF4244 Spa2297_RS30605 3ed68583db3accdb8ce36c5f423ada3f 287 PANTHER PTHR40761:SF1 2 286 4.1E-91 T 16-09-2016 Spa2297_RS30605 3ed68583db3accdb8ce36c5f423ada3f 287 PANTHER PTHR40761 2 286 4.1E-91 T 16-09-2016 Spa2297_RS20505 56f53353408a8a1ecd2798adbd1f62fc 134 Pfam PF10825 Protein of unknown function (DUF2752) 47 95 3.3E-17 T 16-09-2016 IPR021215 Protein of unknown function DUF2752 Spa2297_RS08230 8464d95864b4cf66705d7183044ce438 240 Pfam PF10138 vWA found in TerF C terminus 36 238 6.8E-66 T 16-09-2016 IPR019303 vWA found in TerF C terminus Spa2297_RS08230 8464d95864b4cf66705d7183044ce438 240 Gene3D G3DSA:3.40.50.410 39 183 7.9E-6 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS08230 8464d95864b4cf66705d7183044ce438 240 SUPERFAMILY SSF53300 37 192 3.56E-14 T 16-09-2016 IPR002035 von Willebrand factor, type A Spa2297_RS03725 1be9b2411085d6f0b8d7bfb47f98e866 387 SUPERFAMILY SSF110296 27 384 2.09E-58 T 16-09-2016 Spa2297_RS03725 1be9b2411085d6f0b8d7bfb47f98e866 387 Gene3D G3DSA:2.130.10.10 29 383 1.6E-81 T 16-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 Gene3D G3DSA:3.60.21.10 2 237 4.9E-26 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 PIRSF PIRSF008292 1 238 1.5E-102 T 16-09-2016 IPR016538 Uncharacterised conserved protein UCP008292 Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 SUPERFAMILY SSF56300 2 227 1.76E-30 T 16-09-2016 IPR029052 Metallo-dependent phosphatase-like Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 PANTHER PTHR31302 1 129 6.5E-22 T 16-09-2016 Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 PANTHER PTHR31302 188 223 6.5E-22 T 16-09-2016 Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 PANTHER PTHR31302 154 172 6.5E-22 T 16-09-2016 Spa2297_RS01825 d3faabdc8bff9577bcb7520c058f2bf2 241 Pfam PF00149 Calcineurin-like phosphoesterase 2 207 2.3E-11 T 16-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 Spa2297_RS00910 88a0c7d71154c5213e3b26403a423fcf 357 SUPERFAMILY SSF51395 2 354 8.8E-104 T 16-09-2016 Spa2297_RS00910 88a0c7d71154c5213e3b26403a423fcf 357 PANTHER PTHR22893 2 354 3.2E-139 T 16-09-2016 Spa2297_RS00910 88a0c7d71154c5213e3b26403a423fcf 357 Gene3D G3DSA:3.20.20.70 2 352 5.6E-111 T 16-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 Spa2297_RS00910 88a0c7d71154c5213e3b26403a423fcf 357 PANTHER PTHR22893:SF14 2 354 3.2E-139 T 16-09-2016 Spa2297_RS00910 88a0c7d71154c5213e3b26403a423fcf 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 330 1.5E-70 T 16-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Spa2297_RS21785 b597cfc1ede680b94621068ecc04f276 297 Pfam PF01936 NYN domain 34 180 1.1E-9 T 16-09-2016 IPR021139 NYN domain, limkain-b1-type Spa2297_RS21785 b597cfc1ede680b94621068ecc04f276 297 Gene3D G3DSA:3.40.50.1010 28 176 7.6E-16 T 16-09-2016 IPR029060 PIN domain-like Spa2297_RS15495 76aa18f88861a13e65571e9ff4f52fc0 128 PANTHER PTHR33677:SF3 22 127 7.8E-41 T 16-09-2016 Spa2297_RS15495 76aa18f88861a13e65571e9ff4f52fc0 128 Pfam PF02583 Metal-sensitive transcriptional repressor 43 123 3.9E-30 T 16-09-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Spa2297_RS15495 76aa18f88861a13e65571e9ff4f52fc0 128 PANTHER PTHR33677 22 127 7.8E-41 T 16-09-2016 Spa2297_RS08520 2ae9bbee2f7e7e7335d20a5a88933da4 264 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 27 262 18.526 T 16-09-2016 IPR026579 Cell division protein FtsQ GO:0000917 Spa2297_RS08520 2ae9bbee2f7e7e7335d20a5a88933da4 264 PANTHER PTHR37820 1 261 2.4E-66 T 16-09-2016 Spa2297_RS08520 2ae9bbee2f7e7e7335d20a5a88933da4 264 Pfam PF08478 POTRA domain, FtsQ-type 58 126 1.1E-18 T 16-09-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type Spa2297_RS13025 26bdce3c3bb73f84735db6f2973b9891 450 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 293 370 1.8E-8 T 16-09-2016 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain Spa2297_RS31125 051e46cc4e0f55c87d7b45fb14c53f0d 239 Pfam PF12867 DinB superfamily 17 221 6.8E-9 T 16-09-2016 IPR024775 DinB-like domain Spa2297_RS31125 051e46cc4e0f55c87d7b45fb14c53f0d 239 SUPERFAMILY SSF109854 7 133 1.86E-10 T 16-09-2016 Spa2297_RS31125 051e46cc4e0f55c87d7b45fb14c53f0d 239 SUPERFAMILY SSF109854 122 231 2.2E-5 T 16-09-2016 Spa2297_RS04785 403e3629fd626bffe684056310b711a7 242 Gene3D G3DSA:1.20.120.640 153 207 3.7E-4 T 16-09-2016 Spa2297_RS13470 edab4e7e75965a2d6bb28182cd44a44e 215 SUPERFAMILY SSF109998 32 159 1.73E-16 T 16-09-2016 IPR027304 Trigger factor/SurA domain Spa2297_RS13470 edab4e7e75965a2d6bb28182cd44a44e 215 Pfam PF13624 SurA N-terminal domain 27 153 3.9E-11 T 16-09-2016 Spa2297_RS16990 f88199894d4415162e7023ab6b3546d1 121 PANTHER PTHR35796 1 121 5.3E-46 T 16-09-2016 Spa2297_RS16990 f88199894d4415162e7023ab6b3546d1 121 Gene3D G3DSA:2.30.29.50 3 100 1.4E-42 T 16-09-2016 IPR012544 Bacterial Pleckstrin homology domain Spa2297_RS16990 f88199894d4415162e7023ab6b3546d1 121 SUPERFAMILY SSF50729 3 120 1.72E-43 T 16-09-2016 IPR011993 PH domain-like Spa2297_RS16990 f88199894d4415162e7023ab6b3546d1 121 Pfam PF08000 Bacterial PH domain 3 118 1.2E-47 T 16-09-2016 IPR012544 Bacterial Pleckstrin homology domain Spa2297_RS21815 ea33e858bb78b2cec6b6c9620c7ad0d6 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 2.4E-29 T 16-09-2016 IPR021456 Protein of unknown function DUF3107 Spa2297_RS24995 4596652bfec1ff52caf2683c429a151c 248 SUPERFAMILY SSF53335 35 215 4.85E-28 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS24995 4596652bfec1ff52caf2683c429a151c 248 Gene3D G3DSA:3.40.50.150 35 217 7.9E-18 T 16-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spa2297_RS03415 16c540abdfc08b8ffadbb0aaca72a57c 793 SUPERFAMILY SSF53474 549 682 5.6E-9 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS22030 27baf76f6ab1d535e8b87686bba18b2e 107 PANTHER PTHR30561 1 103 1.0E-65 T 16-09-2016 Spa2297_RS22030 27baf76f6ab1d535e8b87686bba18b2e 107 SUPERFAMILY SSF103481 6 105 1.96E-17 T 16-09-2016 Spa2297_RS22030 27baf76f6ab1d535e8b87686bba18b2e 107 PANTHER PTHR30561:SF10 1 103 1.0E-65 T 16-09-2016 Spa2297_RS22030 27baf76f6ab1d535e8b87686bba18b2e 107 Pfam PF00893 Small Multidrug Resistance protein 1 92 9.7E-24 T 16-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 Spa2297_RS01180 23ef11e75beefc28c9dfd394c7851cb2 290 SUPERFAMILY SSF52266 35 288 9.83E-63 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS01180 23ef11e75beefc28c9dfd394c7851cb2 290 PANTHER PTHR37981:SF3 1 289 4.3E-149 T 16-09-2016 Spa2297_RS01180 23ef11e75beefc28c9dfd394c7851cb2 290 PANTHER PTHR37981 1 289 4.3E-149 T 16-09-2016 Spa2297_RS01180 23ef11e75beefc28c9dfd394c7851cb2 290 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 39 277 1.1E-27 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS01180 23ef11e75beefc28c9dfd394c7851cb2 290 Gene3D G3DSA:3.40.50.1110 32 287 1.9E-65 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS28255 986439c929069284be0d6795ba37e03a 186 Pfam PF03729 Short repeat of unknown function (DUF308) 94 148 1.0E-5 T 16-09-2016 IPR005325 Protein of unknown function DUF308, membrane Spa2297_RS21985 1b9934e6fe428aa8eaa659a1eedd076f 964 Pfam PF03699 Uncharacterised protein family (UPF0182) 13 800 2.6E-284 T 16-09-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 Spa2297_RS21985 1b9934e6fe428aa8eaa659a1eedd076f 964 PANTHER PTHR39344 1 941 0.0 T 16-09-2016 Spa2297_RS21985 1b9934e6fe428aa8eaa659a1eedd076f 964 Hamap MF_01600 UPF0182 protein . 3 875 18.421 T 16-09-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 Spa2297_RS16945 94151965864ed9fb4f08e663a70513e4 156 Pfam PF07179 SseB protein N-terminal domain 42 144 2.0E-7 T 16-09-2016 IPR009839 SseB protein N-terminal domain Spa2297_RS25530 e692a1b00565db7f30102840f75b5cf6 97 SUPERFAMILY SSF54909 3 94 1.34E-25 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS25530 e692a1b00565db7f30102840f75b5cf6 97 Pfam PF02426 Muconolactone delta-isomerase 3 92 4.5E-30 T 16-09-2016 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185|UniPathway: UPA00157 Spa2297_RS21375 e6109b3f8092ec4105fe2fd4a35c0f82 177 Pfam PF14030 Protein of unknown function (DUF4245) 8 174 8.6E-49 T 16-09-2016 IPR025339 Protein of unknown function DUF4245 Spa2297_RS23450 bc3d7948428b82ba9bb4af004ed6ad6c 65 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 4 64 9.8E-16 T 16-09-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit Spa2297_RS12790 6c85413f99aa585d45ae812d10e39e62 392 Pfam PF01757 Acyltransferase family 15 356 5.3E-20 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS10230 ba84dada6d2f880bbe20943a2e66fa4a 402 Pfam PF13556 PucR C-terminal helix-turn-helix domain 335 392 5.2E-12 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS14510 0f44a8d7de445725dc64bb74e36dd1ee 556 PANTHER PTHR13943:SF41 40 544 5.1E-292 T 16-09-2016 Spa2297_RS14510 0f44a8d7de445725dc64bb74e36dd1ee 556 PANTHER PTHR13943 40 544 5.1E-292 T 16-09-2016 Spa2297_RS14510 0f44a8d7de445725dc64bb74e36dd1ee 556 Pfam PF07287 Protein of unknown function (DUF1446) 6 328 9.0E-124 T 16-09-2016 IPR010839 Protein of unknown function DUF1446 Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 PANTHER PTHR31155:SF5 18 323 3.9E-124 T 16-09-2016 Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 Gene3D G3DSA:1.10.620.20 15 311 4.3E-97 T 16-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 PANTHER PTHR31155 18 323 3.9E-124 T 16-09-2016 Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 PIRSF PIRSF000346 4 322 7.1E-90 T 16-09-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 SUPERFAMILY SSF47240 13 307 2.15E-75 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS26585 923c3f30566daec9aa4367d8bfc0d84e 323 Pfam PF03405 Fatty acid desaturase 17 311 6.8E-69 T 16-09-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 Gene3D G3DSA:1.20.1250.20 220 433 1.6E-20 T 16-09-2016 Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 Gene3D G3DSA:1.20.1250.20 10 204 3.9E-20 T 16-09-2016 Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 PANTHER PTHR11360:SF135 8 444 1.8E-153 T 16-09-2016 Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 PANTHER PTHR11360 8 444 1.8E-153 T 16-09-2016 Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 SUPERFAMILY SSF103473 4 426 3.14E-52 T 16-09-2016 IPR020846 Major facilitator superfamily domain Spa2297_RS27325 ad125acfdf6c5509cfd87b2e30e2946f 446 Pfam PF07690 Major Facilitator Superfamily 26 375 1.1E-32 T 16-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spa2297_RS12620 aa4b748a647d8c5a480530e2deac98a1 77 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 21 68 1.0E-9 T 16-09-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spa2297_RS12620 aa4b748a647d8c5a480530e2deac98a1 77 Pfam PF12728 Helix-turn-helix domain 21 70 1.5E-7 T 16-09-2016 Spa2297_RS09605 235f1ff25a83c22e0ea1788b653f3fc6 260 PANTHER PTHR30283:SF3 2 260 1.6E-83 T 16-09-2016 Spa2297_RS09605 235f1ff25a83c22e0ea1788b653f3fc6 260 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 257 21.914 T 16-09-2016 IPR005583 Peroxide stress protein YaaA Spa2297_RS09605 235f1ff25a83c22e0ea1788b653f3fc6 260 PANTHER PTHR30283 2 260 1.6E-83 T 16-09-2016 Spa2297_RS09605 235f1ff25a83c22e0ea1788b653f3fc6 260 Pfam PF03883 Protein of unknown function (DUF328) 2 241 5.9E-41 T 16-09-2016 IPR005583 Peroxide stress protein YaaA Spa2297_RS06755 ca1752c91461fa6bdc240b1f0582c0aa 264 Pfam PF10099 Anti-sigma-K factor rskA 66 254 3.6E-33 T 16-09-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 Spa2297_RS06755 ca1752c91461fa6bdc240b1f0582c0aa 264 PANTHER PTHR37461:SF1 5 262 1.5E-41 T 16-09-2016 Spa2297_RS06755 ca1752c91461fa6bdc240b1f0582c0aa 264 PANTHER PTHR37461 5 262 1.5E-41 T 16-09-2016 Spa2297_RS03860 13ad1cc7c0a08eab5bce20285d4f38d6 243 Gene3D G3DSA:3.40.50.1820 20 242 1.4E-29 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03860 13ad1cc7c0a08eab5bce20285d4f38d6 243 SUPERFAMILY SSF53474 119 243 6.3E-28 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS03860 13ad1cc7c0a08eab5bce20285d4f38d6 243 SUPERFAMILY SSF53474 21 86 6.3E-28 T 16-09-2016 IPR029058 Alpha/Beta hydrolase fold Spa2297_RS06905 b1b58778a229c82266968f23fd6db139 71 Pfam PF11720 Peptidase inhibitor I78 family 32 67 3.7E-7 T 16-09-2016 IPR021719 Proteinase inhibitor I78 Spa2297_RS24355 e5d7b8d5acd96052d4e8b286e51d4594 161 PANTHER PTHR36929 1 161 3.3E-43 T 16-09-2016 Spa2297_RS24355 e5d7b8d5acd96052d4e8b286e51d4594 161 Gene3D G3DSA:3.30.530.20 6 160 3.6E-37 T 16-09-2016 IPR023393 START-like domain Spa2297_RS24355 e5d7b8d5acd96052d4e8b286e51d4594 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 159 4.3E-25 T 16-09-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 Spa2297_RS24355 e5d7b8d5acd96052d4e8b286e51d4594 161 SUPERFAMILY SSF55961 14 160 1.57E-36 T 16-09-2016 Spa2297_RS24355 e5d7b8d5acd96052d4e8b286e51d4594 161 PANTHER PTHR36929:SF1 1 161 3.3E-43 T 16-09-2016 Spa2297_RS26855 fbe108bee2030e16fd3906e38789ec4e 322 PANTHER PTHR30465 1 319 1.3E-122 T 16-09-2016 Spa2297_RS26855 fbe108bee2030e16fd3906e38789ec4e 322 Gene3D G3DSA:1.10.3720.10 90 315 7.7E-12 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26855 fbe108bee2030e16fd3906e38789ec4e 322 SUPERFAMILY SSF161098 94 301 6.54E-9 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS26855 fbe108bee2030e16fd3906e38789ec4e 322 PANTHER PTHR30465:SF24 1 319 1.3E-122 T 16-09-2016 Spa2297_RS26855 fbe108bee2030e16fd3906e38789ec4e 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 318 1.0E-35 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS13520 6d2d7d21a5d6b645af5315154a5c8cc2 296 PANTHER PTHR23242 1 286 1.4E-67 T 16-09-2016 Spa2297_RS13520 6d2d7d21a5d6b645af5315154a5c8cc2 296 PANTHER PTHR23242:SF11 1 286 1.4E-67 T 16-09-2016 Spa2297_RS29910 90ea244eed61e10a7395fad35a5545f4 81 SMART SM00704 29 73 1.9E-13 T 16-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Spa2297_RS29910 90ea244eed61e10a7395fad35a5545f4 81 Pfam PF09360 Iron-binding zinc finger CDGSH type 24 68 2.1E-15 T 16-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 Spa2297_RS16340 e655f294ac81294287d2d4b63c7058a6 145 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 1.1E-32 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS23360 843501907e36c8f4fd0e16168fe4f528 397 Gene3D G3DSA:1.10.10.60 333 371 7.0E-7 T 16-09-2016 IPR009057 Homeodomain-like GO:0003677 Spa2297_RS23360 843501907e36c8f4fd0e16168fe4f528 397 PANTHER PTHR33744:SF5 13 397 7.7E-108 T 16-09-2016 Spa2297_RS23360 843501907e36c8f4fd0e16168fe4f528 397 Pfam PF13556 PucR C-terminal helix-turn-helix domain 336 394 1.1E-21 T 16-09-2016 IPR025736 PucR C-terminal helix-turn-helix domain Spa2297_RS23360 843501907e36c8f4fd0e16168fe4f528 397 PANTHER PTHR33744 13 397 7.7E-108 T 16-09-2016 Spa2297_RS03205 c70843f42e3473b91685b1b19bb81e92 272 SUPERFAMILY SSF161098 3 267 3.64E-58 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS03205 c70843f42e3473b91685b1b19bb81e92 272 PANTHER PTHR32243 1 272 2.2E-179 T 16-09-2016 Spa2297_RS03205 c70843f42e3473b91685b1b19bb81e92 272 PANTHER PTHR32243:SF33 1 272 2.2E-179 T 16-09-2016 Spa2297_RS03205 c70843f42e3473b91685b1b19bb81e92 272 Gene3D G3DSA:1.10.3720.10 4 260 1.9E-52 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS03205 c70843f42e3473b91685b1b19bb81e92 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 263 1.1E-15 T 16-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 Spa2297_RS08250 d696c38f6157dd159849c67b6e795ee4 243 Pfam PF01988 VIT family 28 235 1.2E-62 T 16-09-2016 IPR008217 Ccc1 family Spa2297_RS08250 d696c38f6157dd159849c67b6e795ee4 243 PANTHER PTHR31851 1 243 2.5E-69 T 16-09-2016 Spa2297_RS30740 4e31052fa38638964e12442471eff1e5 317 Pfam PF06675 Protein of unknown function (DUF1177) 41 311 9.5E-132 T 16-09-2016 IPR009561 Protein of unknown function DUF1177 Spa2297_RS17525 efe810957828843d750efd7fec69198f 111 SUPERFAMILY SSF50022 6 87 7.17E-14 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS17525 efe810957828843d750efd7fec69198f 111 Gene3D G3DSA:2.102.10.10 20 61 3.9E-6 T 16-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Spa2297_RS17525 efe810957828843d750efd7fec69198f 111 PANTHER PTHR21266 4 70 3.0E-13 T 16-09-2016 Spa2297_RS25605 c917303c69fb6e1a10a30c5289edb019 394 PANTHER PTHR12260 1 391 9.3E-116 T 16-09-2016 Spa2297_RS25605 c917303c69fb6e1a10a30c5289edb019 394 PANTHER PTHR12260:SF6 1 391 9.3E-116 T 16-09-2016 Spa2297_RS25605 c917303c69fb6e1a10a30c5289edb019 394 Pfam PF01937 Protein of unknown function DUF89 25 369 3.2E-79 T 16-09-2016 IPR002791 Domain of unknown function DUF89 Spa2297_RS25605 c917303c69fb6e1a10a30c5289edb019 394 SUPERFAMILY SSF111321 67 369 7.85E-42 T 16-09-2016 IPR002791 Domain of unknown function DUF89 Spa2297_RS10060 287c12581b34479407a880f394b51fed 307 SUPERFAMILY SSF52266 233 301 7.0E-27 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS10060 287c12581b34479407a880f394b51fed 307 SUPERFAMILY SSF52266 67 204 7.0E-27 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS10060 287c12581b34479407a880f394b51fed 307 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 70 292 4.8E-20 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS10060 287c12581b34479407a880f394b51fed 307 Gene3D G3DSA:3.40.50.1110 239 302 1.3E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS10060 287c12581b34479407a880f394b51fed 307 Gene3D G3DSA:3.40.50.1110 67 203 1.3E-22 T 16-09-2016 IPR013830 SGNH hydrolase-type esterase domain Spa2297_RS30445 0f190607b72b9ca2e3351be2a1fd8c79 546 SUPERFAMILY SSF48452 363 519 3.0E-13 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30445 0f190607b72b9ca2e3351be2a1fd8c79 546 Gene3D G3DSA:1.25.40.10 363 519 9.0E-12 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30445 0f190607b72b9ca2e3351be2a1fd8c79 546 Gene3D G3DSA:1.25.40.10 20 64 7.2E-6 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS30445 0f190607b72b9ca2e3351be2a1fd8c79 546 SMART SM00028 414 447 70.0 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS30445 0f190607b72b9ca2e3351be2a1fd8c79 546 SMART SM00028 20 53 0.22 T 16-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 Spa2297_RS14540 1c330ab17322740952716967326e613e 187 Pfam PF04978 Protein of unknown function (DUF664) 26 182 6.7E-47 T 16-09-2016 IPR007061 Protein of unknown function DUF664 Spa2297_RS14540 1c330ab17322740952716967326e613e 187 SUPERFAMILY SSF109854 14 181 1.25E-39 T 16-09-2016 Spa2297_RS14540 1c330ab17322740952716967326e613e 187 Gene3D G3DSA:1.20.120.450 11 184 8.3E-43 T 16-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase Spa2297_RS00625 141c9fcd66b87a90ef132a57ea734a87 236 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 214 233 4.7E-8 T 16-09-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 Spa2297_RS09155 b6c50e8b8877fc6c088004d87b54f39b 66 Gene3D G3DSA:1.10.1660.10 8 55 4.6E-7 T 16-09-2016 Spa2297_RS09155 b6c50e8b8877fc6c088004d87b54f39b 66 SUPERFAMILY SSF46955 9 58 3.43E-10 T 16-09-2016 IPR009061 Putative DNA-binding domain Spa2297_RS09155 b6c50e8b8877fc6c088004d87b54f39b 66 Pfam PF12728 Helix-turn-helix domain 10 56 2.2E-8 T 16-09-2016 Spa2297_RS17730 4e087140f5e8134aa14eceb0bd1614b8 219 Pfam PF16702 Domain of unknown function (DUF5063) 13 173 7.8E-44 T 16-09-2016 IPR032025 Protein of unknown function DUF5063 Spa2297_RS15930 498a827f16bb63663ecf9660f7662c7e 98 PIRSF PIRSF006909 1 98 1.6E-58 T 16-09-2016 IPR014447 Uncharacterised conserved protein UCP006909 Spa2297_RS19970 76c154e4d96ec007d8e9a1d23b8c1d45 313 TIGRFAM TIGR00271 TIGR00271: uncharacterized hydrophobic domain 112 295 1.2E-61 T 16-09-2016 Spa2297_RS19970 76c154e4d96ec007d8e9a1d23b8c1d45 313 PANTHER PTHR20992 1 308 4.9E-68 T 16-09-2016 Spa2297_RS19970 76c154e4d96ec007d8e9a1d23b8c1d45 313 Pfam PF04087 Domain of unknown function (DUF389) 145 289 2.3E-27 T 16-09-2016 IPR005240 Protein of unknown function DUF389 Spa2297_RS00550 7f3e82e2a9e4a3b77b93b5b42ba88376 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 93 2.4E-10 T 16-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 Spa2297_RS00550 7f3e82e2a9e4a3b77b93b5b42ba88376 142 SUPERFAMILY SSF50475 7 110 8.42E-21 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS00550 7f3e82e2a9e4a3b77b93b5b42ba88376 142 Gene3D G3DSA:2.30.110.10 9 137 5.1E-21 T 16-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 Spa2297_RS20510 bf0612dd22ce0901dd3edaf22281b459 88 Pfam PF05154 TM2 domain 22 70 1.6E-18 T 16-09-2016 IPR007829 TM2 domain Spa2297_RS05010 bb01c23fad48aa6c144339f2ab1a87ed 123 Pfam PF10823 Protein of unknown function (DUF2568) 19 109 4.7E-24 T 16-09-2016 IPR021214 Protein of unknown function DUF2568 Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 PIRSF PIRSF006221 23 284 2.2E-56 T 16-09-2016 IPR016477 Fructosamine/Ketosamine-3-kinase Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 Gene3D G3DSA:3.90.1200.10 91 264 1.2E-15 T 16-09-2016 Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 PANTHER PTHR12149:SF8 35 279 4.6E-35 T 16-09-2016 Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 PANTHER PTHR12149 35 279 4.6E-35 T 16-09-2016 Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 Pfam PF03881 Fructosamine kinase 46 278 1.4E-39 T 16-09-2016 IPR016477 Fructosamine/Ketosamine-3-kinase Spa2297_RS01875 9d565109efcde846257c5ae6ae4f16b4 285 SUPERFAMILY SSF56112 24 274 8.85E-39 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS04275 c051c562c95435920e3c3b4a191e494e 639 Pfam PF04434 SWIM zinc finger 48 92 4.0E-4 T 16-09-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 Pfam PF00144 Beta-lactamase 19 393 2.6E-65 T 16-09-2016 IPR001466 Beta-lactamase-related Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 PANTHER PTHR10566 100 205 5.4E-62 T 16-09-2016 Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 SUPERFAMILY SSF56601 8 397 6.82E-60 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 Gene3D G3DSA:3.40.710.10 6 225 6.8E-71 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 Gene3D G3DSA:3.40.710.10 259 401 6.8E-71 T 16-09-2016 IPR012338 Beta-lactamase/transpeptidase-like Spa2297_RS13755 2f3a29661a3e007292e9043e5069beba 411 PANTHER PTHR10566:SF94 100 205 5.4E-62 T 16-09-2016 Spa2297_RS17550 4089a4b8ec8d980d3233ff96214bd99e 178 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 167 1.0E-88 T 16-09-2016 IPR024486 Protein of unknown function DUF2617 Spa2297_RS17550 4089a4b8ec8d980d3233ff96214bd99e 178 Pfam PF10936 Protein of unknown function DUF2617 3 164 2.9E-63 T 16-09-2016 IPR024486 Protein of unknown function DUF2617 Spa2297_RS28805 9b9e61b0f3f39641636723badbb5813a 190 SUPERFAMILY SSF55729 15 164 2.66E-18 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28805 9b9e61b0f3f39641636723badbb5813a 190 Gene3D G3DSA:3.40.630.30 16 163 3.2E-17 T 16-09-2016 IPR016181 Acyl-CoA N-acyltransferase Spa2297_RS28805 9b9e61b0f3f39641636723badbb5813a 190 Pfam PF00583 Acetyltransferase (GNAT) family 62 160 7.9E-10 T 16-09-2016 IPR000182 GNAT domain GO:0008080 Spa2297_RS18430 68e5fdec3d8671b9de8acaa47d381cf7 588 SUPERFAMILY SSF88946 25 115 3.3E-5 T 16-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spa2297_RS18430 68e5fdec3d8671b9de8acaa47d381cf7 588 Gene3D G3DSA:2.60.40.360 429 510 1.9E-4 T 16-09-2016 IPR008962 PapD-like Spa2297_RS18430 68e5fdec3d8671b9de8acaa47d381cf7 588 Gene3D G3DSA:1.10.1740.10 25 134 9.2E-7 T 16-09-2016 Spa2297_RS26675 e2bc20190825648c8dcc12e5f31ee4f0 324 Gene3D G3DSA:1.10.620.20 99 203 1.3E-6 T 16-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 Spa2297_RS26675 e2bc20190825648c8dcc12e5f31ee4f0 324 SUPERFAMILY SSF47240 99 219 2.61E-14 T 16-09-2016 IPR009078 Ferritin-like superfamily Spa2297_RS02375 bfe54fdc11f02cdc9cdadfce23864e80 146 Pfam PF03779 SPW repeat 37 84 2.4E-17 T 16-09-2016 IPR005530 SPW repeat Spa2297_RS02375 bfe54fdc11f02cdc9cdadfce23864e80 146 Pfam PF03779 SPW repeat 92 138 4.4E-18 T 16-09-2016 IPR005530 SPW repeat Spa2297_RS31995 60d4b47d622ef393d5c7cbe119374442 459 Gene3D G3DSA:3.30.2010.10 146 190 7.2E-4 T 16-09-2016 Spa2297_RS25540 3e546c34223ed39fd96088af1d971cc2 180 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 16 107 3.2E-9 T 16-09-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 Spa2297_RS31705 f35c8eb6810ff7e1b01bba42bf56228d 182 Gene3D G3DSA:3.40.430.10 28 181 1.2E-21 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS31705 f35c8eb6810ff7e1b01bba42bf56228d 182 Pfam PF01872 RibD C-terminal domain 25 173 3.3E-14 T 16-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spa2297_RS31705 f35c8eb6810ff7e1b01bba42bf56228d 182 PANTHER PTHR38011:SF2 2 182 1.4E-32 T 16-09-2016 Spa2297_RS31705 f35c8eb6810ff7e1b01bba42bf56228d 182 SUPERFAMILY SSF53597 3 180 2.09E-25 T 16-09-2016 IPR024072 Dihydrofolate reductase-like domain Spa2297_RS31705 f35c8eb6810ff7e1b01bba42bf56228d 182 PANTHER PTHR38011 2 182 1.4E-32 T 16-09-2016 Spa2297_RS08310 3d61db2639a486fb1362f0e946adb020 150 Pfam PF10825 Protein of unknown function (DUF2752) 56 104 2.1E-16 T 16-09-2016 IPR021215 Protein of unknown function DUF2752 Spa2297_RS12575 7520b583f2e89bb547e51e1b46712854 156 Pfam PF13581 Histidine kinase-like ATPase domain 22 134 1.6E-9 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS12575 7520b583f2e89bb547e51e1b46712854 156 SUPERFAMILY SSF55874 33 139 8.65E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS15030 7183c650f81a98676dca7fdd8082153c 652 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 614 3.4E-219 T 16-09-2016 IPR011749 Conserved hypothetical protein CHP02243 Spa2297_RS15030 7183c650f81a98676dca7fdd8082153c 652 Pfam PF04865 Baseplate J-like protein 398 572 3.3E-11 T 16-09-2016 IPR006949 Baseplate protein J-like Spa2297_RS29635 4b28685b50358afaa3c2dae426e3ddc6 251 Pfam PF02754 Cysteine-rich domain 3 83 8.7E-15 T 16-09-2016 IPR004017 Cysteine-rich domain Spa2297_RS29635 4b28685b50358afaa3c2dae426e3ddc6 251 Pfam PF02754 Cysteine-rich domain 138 222 2.8E-17 T 16-09-2016 IPR004017 Cysteine-rich domain Spa2297_RS29635 4b28685b50358afaa3c2dae426e3ddc6 251 PANTHER PTHR30296 2 251 9.6E-127 T 16-09-2016 Spa2297_RS29635 4b28685b50358afaa3c2dae426e3ddc6 251 PANTHER PTHR30296:SF0 2 251 9.6E-127 T 16-09-2016 Spa2297_RS27985 034271d14b126d094f2ef6eb1355313d 138 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 1.4E-30 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS29775 084460d9162d23a35a79bf1a023a3c9a 165 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 162 3.9E-62 T 16-09-2016 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger Spa2297_RS18725 0643a4e19b014fe2bc9e1fe8bf8b3063 150 Pfam PF14342 Domain of unknown function (DUF4396) 9 141 9.2E-41 T 16-09-2016 IPR025509 Domain of unknown function DUF4396 Spa2297_RS24375 77c1c0ccb2212a0822a48f9cea06e931 253 PANTHER PTHR34979 1 243 1.6E-53 T 16-09-2016 Spa2297_RS24375 77c1c0ccb2212a0822a48f9cea06e931 253 Pfam PF03591 AzlC protein 28 164 3.3E-27 T 16-09-2016 IPR011606 Branched-chain amino acid transport, permease Spa2297_RS26100 105f12a23f01429c4e8be7d4399f9513 349 Pfam PF10935 Protein of unknown function (DUF2637) 69 217 4.1E-24 T 16-09-2016 IPR021235 Protein of unknown function DUF2637 Spa2297_RS08950 0effd2f58d4a7076857b5a93805e33ee 258 Pfam PF04012 PspA/IM30 family 2 222 6.1E-28 T 16-09-2016 IPR007157 PspA/IM30 Spa2297_RS08950 0effd2f58d4a7076857b5a93805e33ee 258 PANTHER PTHR31088 2 258 3.0E-79 T 16-09-2016 Spa2297_RS08950 0effd2f58d4a7076857b5a93805e33ee 258 PANTHER PTHR31088:SF0 2 258 3.0E-79 T 16-09-2016 Spa2297_RS18090 4feed023964ff727b70cdc8f82cf8830 89 Pfam PF04149 Domain of unknown function (DUF397) 26 79 3.7E-18 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS19515 1ba88cdf660f43b508d6095a21e70f2d 88 PANTHER PTHR33884 1 88 1.1E-22 T 16-09-2016 Spa2297_RS19515 1ba88cdf660f43b508d6095a21e70f2d 88 Pfam PF04226 Transglycosylase associated protein 33 83 3.5E-8 T 16-09-2016 IPR007341 Transglycosylase-associated protein GO:0016021 Spa2297_RS27620 4362c091266119d235400224142d319a 256 Pfam PF01066 CDP-alcohol phosphatidyltransferase 73 140 1.1E-8 T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS27620 4362c091266119d235400224142d319a 256 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 118 140 - T 16-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spa2297_RS01335 44909e27190f00cf9c388d0ccce6e8ab 131 Pfam PF04138 GtrA-like protein 9 125 2.4E-9 T 16-09-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 Spa2297_RS17940 a0d33941ce620eb28268e2469cdddc82 290 Pfam PF00482 Type II secretion system (T2SS), protein F 121 243 7.3E-10 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS12515 5012b1f52a7967b3e58d7eff01d605f4 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 24 121 3.7E-35 T 16-09-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 Spa2297_RS21680 30db93d42cfa924c0f3e289a6af4a062 119 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 53 82 1.3E-7 T 16-09-2016 IPR019933 DivIVA domain Spa2297_RS14220 aa334ace1f269ea07c6267308cf41b39 63 Pfam PF04149 Domain of unknown function (DUF397) 10 62 2.2E-21 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS07245 ca850612f379b1fa02d985e0366103e3 136 Pfam PF11298 Protein of unknown function (DUF3099) 13 81 1.3E-23 T 16-09-2016 IPR021449 Protein of unknown function DUF3099 Spa2297_RS18645 0e36a9705c8c41b2c884dce551fa0adb 428 PANTHER PTHR23242 1 328 2.6E-48 T 16-09-2016 Spa2297_RS18645 0e36a9705c8c41b2c884dce551fa0adb 428 Pfam PF10935 Protein of unknown function (DUF2637) 17 171 2.2E-43 T 16-09-2016 IPR021235 Protein of unknown function DUF2637 Spa2297_RS23150 10b760494764532588b398d3fdc7d60c 265 Pfam PF14581 SseB protein C-terminal domain 137 241 8.2E-19 T 16-09-2016 IPR027945 SseB protein, C-terminal Spa2297_RS23480 78624e094a6bc5a6934d8bd3c38a630e 132 PANTHER PTHR36221 1 132 2.8E-42 T 16-09-2016 Spa2297_RS23480 78624e094a6bc5a6934d8bd3c38a630e 132 Pfam PF05331 Protein of unknown function (DUF742) 20 132 5.3E-39 T 16-09-2016 IPR007995 Protein of unknown function DUF742 Spa2297_RS14055 beaf0ab1833de500b9a0cc54ebb33436 142 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 17 138 1.3E-30 T 16-09-2016 IPR018727 Protein of unknown function DUF2267 Spa2297_RS11440 3e4f4d947cfc6ffa472341df1a2d3983 79 Pfam PF03777 Small secreted domain (DUF320) 23 78 3.1E-30 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS23700 7a868c0600634bd8a4fd8e8bcb63fa03 223 SMART SM00943 32 211 4.1E-32 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS23700 7a868c0600634bd8a4fd8e8bcb63fa03 223 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 40 203 1.8E-13 T 16-09-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal Spa2297_RS29470 bbe5bbf6e544cce4b4ea471a90fedae6 76 Pfam PF11160 Protein of unknown function (DUF2945) 14 74 6.2E-25 T 16-09-2016 IPR021331 Protein of unknown function DUF2945 Spa2297_RS14165 f396ec32cca619387d42bd8493a6f889 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 7.7E-11 T 16-09-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 Spa2297_RS14165 f396ec32cca619387d42bd8493a6f889 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 1.4E-9 T 16-09-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 Spa2297_RS13235 b1e951d3268c38d5383592e41e17b6bd 123 SUPERFAMILY SSF54593 6 122 8.06E-19 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS13235 b1e951d3268c38d5383592e41e17b6bd 123 PANTHER PTHR35908 2 123 2.1E-60 T 16-09-2016 Spa2297_RS13235 b1e951d3268c38d5383592e41e17b6bd 123 PANTHER PTHR35908:SF2 2 123 2.1E-60 T 16-09-2016 Spa2297_RS13235 b1e951d3268c38d5383592e41e17b6bd 123 Gene3D G3DSA:3.10.180.10 9 121 1.1E-15 T 16-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spa2297_RS30745 e206d62fd24a36cf83f1811c0c9e65aa 471 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 37 389 1.7E-19 T 16-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 Spa2297_RS30745 e206d62fd24a36cf83f1811c0c9e65aa 471 PANTHER PTHR30569 21 462 3.0E-110 T 16-09-2016 IPR030191 Cytosine permease GO:0015209|GO:0016021 Spa2297_RS20350 d3844afb163f45397ee289a1c230f14d 176 Pfam PF11222 Protein of unknown function (DUF3017) 84 153 7.7E-20 T 16-09-2016 IPR021385 Protein of unknown function DUF3017 Spa2297_RS18605 9d99f089c35efbad4952628e0a93361e 152 Gene3D G3DSA:1.10.10.10 12 146 2.5E-16 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS18605 9d99f089c35efbad4952628e0a93361e 152 SUPERFAMILY SSF46785 5 144 6.26E-14 T 16-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain Spa2297_RS09140 c5e74690686fffc182b4347007c2d958 568 Pfam PF06048 Domain of unknown function (DUF927) 31 300 1.1E-40 T 16-09-2016 IPR009270 Domain of unknown function DUF927 Spa2297_RS19445 d29d036627eab708748c0f541baee95f 138 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 38 137 1.2E-29 T 16-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Spa2297_RS19445 d29d036627eab708748c0f541baee95f 138 PANTHER PTHR11058:SF9 12 138 1.9E-41 T 16-09-2016 Spa2297_RS19445 d29d036627eab708748c0f541baee95f 138 PANTHER PTHR11058 12 138 1.9E-41 T 16-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Spa2297_RS08040 783fc769341438427339cba593fc4d13 602 Pfam PF13515 Fusaric acid resistance protein-like 350 466 1.9E-15 T 16-09-2016 Spa2297_RS18650 83ca5ca1a0f8e9e8c09d21ab19ecd888 284 Pfam PF12079 Protein of unknown function (DUF3558) 42 154 1.4E-10 T 16-09-2016 IPR024520 Protein of unknown function DUF3558 Spa2297_RS15455 1177680c1881b9046b9f292d6424b9d9 383 SMART SM00880 28 369 1.1E-7 T 16-09-2016 IPR007899 CHAD domain Spa2297_RS15455 1177680c1881b9046b9f292d6424b9d9 383 Pfam PF05235 CHAD domain 45 333 1.8E-25 T 16-09-2016 IPR007899 CHAD domain Spa2297_RS29945 bb7f3af3e622e8d61ca4a690ab900f75 71 Gene3D G3DSA:2.40.30.20 7 51 1.9E-5 T 16-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 Spa2297_RS31515 b41c1708e5cda369727a213f0f74604b 248 Pfam PF08894 Protein of unknown function (DUF1838) 22 244 8.5E-78 T 16-09-2016 IPR014990 Protein of unknown function DUF1838 Spa2297_RS02450 021be4a41725d4ba264b6600d255cf7d 80 Pfam PF04149 Domain of unknown function (DUF397) 24 73 1.6E-10 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS20200 9b139115e50d1e1e1790cc42ce0e6510 176 Pfam PF07681 DoxX 27 129 4.6E-22 T 16-09-2016 IPR032808 DoxX family Spa2297_RS20200 9b139115e50d1e1e1790cc42ce0e6510 176 PANTHER PTHR39157 4 172 6.0E-54 T 16-09-2016 Spa2297_RS13385 91dbf3ff323a0dd2c5ff8ba8a52e6758 76 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 8.2E-24 T 16-09-2016 IPR025629 Protein of unknown function DUF4287 Spa2297_RS15195 f42bc188218cfa4d2090b5b950f98b03 113 Pfam PF10724 Protein of unknown function (DUF2516) 9 92 6.4E-30 T 16-09-2016 IPR019662 Protein of unknown function DUF2516 Spa2297_RS13350 c6745604bbd80f6eb8dda8e9ddf10138 152 SUPERFAMILY SSF52799 52 142 5.71E-16 T 16-09-2016 IPR029021 Protein-tyrosine phosphatase-like Spa2297_RS13350 c6745604bbd80f6eb8dda8e9ddf10138 152 Gene3D G3DSA:3.90.190.10 55 142 5.6E-13 T 16-09-2016 IPR029021 Protein-tyrosine phosphatase-like Spa2297_RS01935 837787cdd28db67467411030c5683635 126 Pfam PF13564 DoxX-like family 9 96 6.3E-6 T 16-09-2016 IPR032808 DoxX family Spa2297_RS01935 837787cdd28db67467411030c5683635 126 PANTHER PTHR36974 2 126 2.9E-36 T 16-09-2016 Spa2297_RS15130 ffda4c927cd8391fc181bd6f871aeeeb 89 Pfam PF08922 Domain of unknown function (DUF1905) 5 83 3.0E-26 T 16-09-2016 IPR015018 Protein of unknown function DUF1905 Spa2297_RS15130 ffda4c927cd8391fc181bd6f871aeeeb 89 Gene3D G3DSA:2.40.30.100 3 86 2.1E-32 T 16-09-2016 Spa2297_RS15130 ffda4c927cd8391fc181bd6f871aeeeb 89 SUPERFAMILY SSF141694 3 85 2.01E-26 T 16-09-2016 Spa2297_RS13535 f6510ca06458d3e1eb40d00f419fb430 176 Pfam PF14431 YwqJ-like deaminase 38 166 1.5E-20 T 16-09-2016 IPR025968 YwqJ-like deaminase Spa2297_RS25355 a65e2afcde4dfe69931a4adf6fac2c90 211 Pfam PF11452 Protein of unknown function (DUF3000) 19 193 3.9E-70 T 16-09-2016 IPR021555 Protein of unknown function DUF3000 Spa2297_RS17795 2b9cef7b7f9e9a9939fe3f33482976a5 96 Pfam PF11239 Protein of unknown function (DUF3040) 5 75 7.0E-11 T 16-09-2016 IPR021401 Protein of unknown function DUF3040 Spa2297_RS16985 c107ae433fd55535dc3c18ca4c699d68 66 Pfam PF04149 Domain of unknown function (DUF397) 10 62 1.0E-18 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS06525 a224794e7b611e7aa47e7eda610fabc0 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 5.5E-30 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS12360 3cad4fadfeb29aa89d38ed3f5ccdbdeb 264 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 1.9E-23 T 16-09-2016 IPR012551 Protein of unknown function DUF1707 Spa2297_RS12360 3cad4fadfeb29aa89d38ed3f5ccdbdeb 264 PANTHER PTHR40763 4 262 1.7E-131 T 16-09-2016 Spa2297_RS12360 3cad4fadfeb29aa89d38ed3f5ccdbdeb 264 PANTHER PTHR40763:SF1 4 262 1.7E-131 T 16-09-2016 Spa2297_RS24220 5cfd23c78907c29b758e225e8155b0b4 97 Pfam PF04149 Domain of unknown function (DUF397) 30 80 3.8E-9 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS24045 894057cc0b1124465cdbe3d113a2b04a 229 Gene3D G3DSA:1.20.144.10 23 205 2.1E-21 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS24045 894057cc0b1124465cdbe3d113a2b04a 229 SUPERFAMILY SSF48317 16 206 2.49E-21 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS24045 894057cc0b1124465cdbe3d113a2b04a 229 Pfam PF01569 PAP2 superfamily 125 204 8.8E-12 T 16-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spa2297_RS06135 dd13a708819694d4504330957f99b187 446 SUPERFAMILY SSF48452 213 318 1.61E-5 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS06135 dd13a708819694d4504330957f99b187 446 Gene3D G3DSA:1.25.40.10 225 418 4.1E-8 T 16-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 Spa2297_RS31430 9c3f04cf03285ae5d99a47c6bb7d2c33 307 Pfam PF14100 Methane oxygenase PmoA 18 302 1.1E-77 T 16-09-2016 IPR029475 Methane oxygenase PmoA Spa2297_RS17595 c1472d5e8e88f2a28ea94f874d3c8185 137 PIRSF PIRSF017349 1 137 1.7E-71 T 16-09-2016 IPR014487 Protein of unknown function DUF3151 Spa2297_RS17595 c1472d5e8e88f2a28ea94f874d3c8185 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 2.7E-59 T 16-09-2016 IPR014487 Protein of unknown function DUF3151 Spa2297_RS16955 eece00d8632f99039ba58c49a22d3481 356 PANTHER PTHR21716 18 356 3.6E-70 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS16955 eece00d8632f99039ba58c49a22d3481 356 Pfam PF01594 Domain of unknown function DUF20 17 333 2.9E-55 T 16-09-2016 IPR002549 Transmembrane protein TqsA-like Spa2297_RS10055 fcfcb05abe807166a71a8e459d595339 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 2.1E-73 T 16-09-2016 IPR021491 Protein of unknown function DUF3145 Spa2297_RS29375 7956120697d5207e3ecb4838c28d170b 127 Gene3D G3DSA:3.40.50.10400 8 113 8.5E-4 T 16-09-2016 IPR027269 Hypothetical PA1492 domain Spa2297_RS24590 9d111691622d962a014178b7bf7fbf8d 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 2.3E-29 T 16-09-2016 IPR032555 Domain of unknown function DUF4937 Spa2297_RS24590 9d111691622d962a014178b7bf7fbf8d 201 SUPERFAMILY SSF54909 16 80 8.72E-6 T 16-09-2016 IPR011008 Dimeric alpha-beta barrel Spa2297_RS26020 589c126cde8028753523c43a97815c9a 234 Pfam PF14342 Domain of unknown function (DUF4396) 89 231 9.1E-40 T 16-09-2016 IPR025509 Domain of unknown function DUF4396 Spa2297_RS09875 40ece01a343e9b1337b199b1204d084c 75 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 72 1.6E-27 T 16-09-2016 IPR018735 Protein of unknown function DUF2277 Spa2297_RS00805 525679e0d8c84ded92f7f79d4e1d2bd8 274 Pfam PF14344 Domain of unknown function (DUF4397) 39 153 5.9E-24 T 16-09-2016 IPR025510 Domain of unknown function DUF4397 Spa2297_RS25295 51e013a5c469d728fe2ed4055e0f0e85 340 SUPERFAMILY SSF89372 5 277 3.14E-24 T 16-09-2016 Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 Gene3D G3DSA:1.25.10.10 54 98 3.2E-14 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 Gene3D G3DSA:1.25.10.10 131 194 3.2E-14 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 SUPERFAMILY SSF48371 51 183 4.03E-10 T 16-09-2016 IPR016024 Armadillo-type fold GO:0005488 Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 SMART SM00567 E-Z type HEAT repeats 51 80 19.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 SMART SM00567 E-Z type HEAT repeats 151 180 2.1 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 SMART SM00567 E-Z type HEAT repeats 112 143 720.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 SMART SM00567 E-Z type HEAT repeats 82 111 150.0 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS26950 c7e487cbab41b61ccad86a5ede722e48 197 Pfam PF03130 PBS lyase HEAT-like repeat 154 178 0.0032 T 16-09-2016 IPR004155 PBS lyase HEAT-like repeat Spa2297_RS09215 30dd8bac6b7da860aed5e5d5fe2684d8 394 PANTHER PTHR38479:SF2 4 390 1.6E-118 T 16-09-2016 Spa2297_RS09215 30dd8bac6b7da860aed5e5d5fe2684d8 394 Pfam PF06224 Winged helix DNA-binding domain 39 374 2.9E-58 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS09215 30dd8bac6b7da860aed5e5d5fe2684d8 394 PANTHER PTHR38479 4 390 1.6E-118 T 16-09-2016 Spa2297_RS30680 37535729f028f20e38e675085ce90321 240 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 133 2.7E-10 T 16-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spa2297_RS30680 37535729f028f20e38e675085ce90321 240 SUPERFAMILY SSF56176 4 134 9.35E-15 T 16-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 Spa2297_RS30680 37535729f028f20e38e675085ce90321 240 Gene3D G3DSA:3.30.465.10 66 135 1.6E-8 T 16-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 Spa2297_RS09770 a1c08423a57a2a2f2822b4ceb4b204ad 135 Pfam PF09350 Domain of unknown function (DUF1992) 14 80 1.9E-19 T 16-09-2016 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain Spa2297_RS27075 5a385252e8e183320e8baadc61f34798 87 Pfam PF05120 Gas vesicle protein G 7 82 4.4E-29 T 16-09-2016 IPR007804 Gas vesicle protein GvpG Spa2297_RS20390 db87a651801eeb80c674c4b9578fed0b 240 PANTHER PTHR21631:SF18 5 217 2.7E-58 T 16-09-2016 Spa2297_RS20390 db87a651801eeb80c674c4b9578fed0b 240 Gene3D G3DSA:3.20.20.60 4 220 5.2E-56 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS20390 db87a651801eeb80c674c4b9578fed0b 240 SUPERFAMILY SSF51621 4 239 3.14E-50 T 16-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 Spa2297_RS20390 db87a651801eeb80c674c4b9578fed0b 240 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 238 8.5E-63 T 16-09-2016 Spa2297_RS20390 db87a651801eeb80c674c4b9578fed0b 240 PANTHER PTHR21631 5 217 2.7E-58 T 16-09-2016 Spa2297_RS27500 7ea0d9be243f6a89e942150bea5bb1a3 609 PANTHER PTHR10066:SF12 205 609 2.5E-202 T 16-09-2016 Spa2297_RS27500 7ea0d9be243f6a89e942150bea5bb1a3 609 PANTHER PTHR10066 205 609 2.5E-202 T 16-09-2016 Spa2297_RS17740 15fd4e2802173ecff55acd18b6509d19 61 Pfam PF04149 Domain of unknown function (DUF397) 6 58 1.4E-21 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS08780 3c5ae850918ee32083decd49cd5597da 386 SUPERFAMILY SSF55486 177 383 1.9E-5 T 16-09-2016 Spa2297_RS14125 5481a1ae839fe6f84f852cdddb5ef6b2 163 Pfam PF11188 Protein of unknown function (DUF2975) 39 163 6.7E-26 T 16-09-2016 IPR021354 Protein of unknown function DUF2975 Spa2297_RS11345 c05e44b479470f31c7bfd9b871c9abfd 227 PIRSF PIRSF012637 1 225 3.2E-67 T 16-09-2016 IPR016601 Uncharacterised conserved protein UCP012637 Spa2297_RS04115 646db2655626e57365df919b79d743db 264 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 257 9.6E-37 T 16-09-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase Spa2297_RS14980 072df6e13eaed1d661a3bec54e24aeec 216 Pfam PF13699 Domain of unknown function (DUF4157) 89 161 7.7E-17 T 16-09-2016 IPR025295 Domain of unknown function DUF4157 Spa2297_RS02300 d3458dd19e84a4032f11ec1499220b25 151 SUPERFAMILY SSF55874 64 148 5.27E-6 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS11500 820cffc4ad3f6ee04aa77b2bd657bd25 75 Pfam PF03777 Small secreted domain (DUF320) 19 74 1.9E-30 T 16-09-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species Spa2297_RS16065 d594ebe55cab75e34d98ed1fed732ec8 212 Pfam PF10977 Protein of unknown function (DUF2797) 8 186 3.3E-31 T 16-09-2016 IPR021246 Protein of unknown function DUF2797 Spa2297_RS32060 6748c3b4d08671e5abd96e9842470b2c 221 SUPERFAMILY SSF52317 5 220 8.93E-33 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS32060 6748c3b4d08671e5abd96e9842470b2c 221 Pfam PF06283 Trehalose utilisation 5 218 6.4E-35 T 16-09-2016 IPR029010 ThuA-like domain Spa2297_RS32060 6748c3b4d08671e5abd96e9842470b2c 221 Gene3D G3DSA:3.40.50.880 3 220 8.7E-40 T 16-09-2016 IPR029062 Class I glutamine amidotransferase-like Spa2297_RS10075 ba07e61e30f5ceb2a46117b49a2ce78b 429 SUPERFAMILY SSF53182 173 313 2.35E-26 T 16-09-2016 Spa2297_RS10075 ba07e61e30f5ceb2a46117b49a2ce78b 429 SUPERFAMILY SSF53182 341 421 2.35E-26 T 16-09-2016 Spa2297_RS10075 ba07e61e30f5ceb2a46117b49a2ce78b 429 Gene3D G3DSA:3.40.630.20 174 397 2.2E-10 T 16-09-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like Spa2297_RS21085 1487d5fafa53923c2e485648d68f77e5 406 PANTHER PTHR38432 40 400 1.6E-71 T 16-09-2016 Spa2297_RS21085 1487d5fafa53923c2e485648d68f77e5 406 Pfam PF05816 Toxic anion resistance protein (TelA) 75 390 4.4E-84 T 16-09-2016 IPR008863 Toxic anion resistance Spa2297_RS21085 1487d5fafa53923c2e485648d68f77e5 406 PANTHER PTHR38432:SF1 40 400 1.6E-71 T 16-09-2016 Spa2297_RS28385 d53a82c4c75e4f00d35259a44c5c7809 110 PANTHER PTHR40630 3 110 1.1E-40 T 16-09-2016 Spa2297_RS28385 d53a82c4c75e4f00d35259a44c5c7809 110 Pfam PF11338 Protein of unknown function (DUF3140) 13 101 5.8E-26 T 16-09-2016 IPR021487 Protein of unknown function DUF3140 Spa2297_RS09970 8cc71ba96c05f3fc8546d63fc0ebdf96 145 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 2.2E-54 T 16-09-2016 IPR021412 Protein of unknown function DUF3052 Spa2297_RS16185 9636d732aaca4848daf093e3f73be5d4 253 Pfam PF07987 Domain of unkown function (DUF1775) 27 175 1.6E-52 T 16-09-2016 IPR012533 GLE1, N-terminal, bacteria Spa2297_RS22090 39f40f3fdaae27ffd9ceef50a518a20d 361 SUPERFAMILY SSF48576 30 337 3.45E-51 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS22090 39f40f3fdaae27ffd9ceef50a518a20d 361 Gene3D G3DSA:1.10.600.10 21 337 2.4E-86 T 16-09-2016 IPR008949 Isoprenoid synthase domain Spa2297_RS13440 962d1a28d5aa00c09b9fbf3abf3f7f91 160 Pfam PF04977 Septum formation initiator 47 125 4.0E-17 T 16-09-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 Spa2297_RS29730 1ea91c5c33981fc0db5332b44b1c41d7 418 Pfam PF06081 Aromatic acid exporter family member 1 27 161 2.1E-8 T 16-09-2016 IPR010343 Aromatic acid exporter family member 1 Spa2297_RS02030 edd72cebe63c25841813c08cc30e95e4 144 SUPERFAMILY SSF55874 50 143 2.06E-8 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02030 edd72cebe63c25841813c08cc30e95e4 144 Pfam PF13581 Histidine kinase-like ATPase domain 27 138 1.8E-11 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS02030 edd72cebe63c25841813c08cc30e95e4 144 Gene3D G3DSA:3.30.565.10 52 143 8.7E-4 T 16-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain Spa2297_RS01570 fc14eea176e5b3419a265a757c857ed8 253 Pfam PF03413 Peptidase propeptide and YPEB domain 87 165 0.0067 T 16-09-2016 IPR025711 PepSY domain Spa2297_RS01570 fc14eea176e5b3419a265a757c857ed8 253 Pfam PF03413 Peptidase propeptide and YPEB domain 189 247 2.6E-9 T 16-09-2016 IPR025711 PepSY domain Spa2297_RS15095 20992b861588b9439e4470368a508565 246 SUPERFAMILY SSF110087 42 161 3.79E-6 T 16-09-2016 IPR007410 DR1885-like metal-binding protein Spa2297_RS31410 000d15fd2922728bbf196e92eb904b82 235 Pfam PF14016 Protein of unknown function (DUF4232) 100 226 1.1E-33 T 16-09-2016 IPR025326 Protein of unknown function DUF4232 Spa2297_RS28985 d22dd1930f92f402a3ed56c7e53c22d6 244 Pfam PF14023 Protein of unknown function (DUF4239) 39 225 9.9E-23 T 16-09-2016 IPR025333 Protein of unknown function DUF4239 Spa2297_RS28555 789be2066deea0e1379eab6dcaf830a8 273 Gene3D G3DSA:2.60.120.620 178 263 5.8E-5 T 16-09-2016 Spa2297_RS10315 3b57835daa951120579de366fe06b5bb 478 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 1 149 7.9E-68 T 16-09-2016 IPR009827 Dicarboxylate carrier MatC N-terminal Spa2297_RS12505 955cc49318e7c65dd0c7c1bb64ff3734 148 Pfam PF06271 RDD family 5 141 8.5E-29 T 16-09-2016 IPR010432 RDD Spa2297_RS20645 127a79cea1595d6d600d3281b4f7c886 446 SUPERFAMILY SSF53756 110 309 2.26E-8 T 16-09-2016 Spa2297_RS12760 8dd3c33175d0f7a120f1daf8403474d2 261 Pfam PF13490 Putative zinc-finger 13 39 2.9E-7 T 16-09-2016 IPR027383 Putative zinc-finger Spa2297_RS07320 10f1e7f9e91bb56ea20613a94cd2554c 127 Pfam PF03780 Asp23 family, cell envelope-related function 23 111 1.0E-6 T 16-09-2016 IPR005531 Alkaline shock protein Asp23 Spa2297_RS09715 2084cadc1c9e9dbc6b09e803ae805eb2 371 Pfam PF02361 Cobalt transport protein 24 230 3.4E-9 T 16-09-2016 IPR003339 ABC/ECF transporter, transmembrane component Spa2297_RS03405 bb5db21ac7bc451493c579a3a9fe722b 200 PANTHER PTHR42305 1 200 4.2E-65 T 16-09-2016 Spa2297_RS22560 7d1e6e0105df4174fc8fac38e1734424 167 Gene3D G3DSA:3.10.590.10 13 143 1.0E-4 T 16-09-2016 IPR002740 EVE domain Spa2297_RS05925 8b7fd8cb7c9eb1055fac2eddbeb869ad 310 Gene3D G3DSA:3.90.1200.10 106 244 5.7E-17 T 16-09-2016 Spa2297_RS05925 8b7fd8cb7c9eb1055fac2eddbeb869ad 310 Pfam PF01636 Phosphotransferase enzyme family 59 247 1.8E-14 T 16-09-2016 IPR002575 Aminoglycoside phosphotransferase Spa2297_RS05925 8b7fd8cb7c9eb1055fac2eddbeb869ad 310 SUPERFAMILY SSF56112 57 251 3.57E-20 T 16-09-2016 IPR011009 Protein kinase-like domain Spa2297_RS13490 92d896b9d92974671a17514c6eb3328e 66 Pfam PF14013 MT0933-like antitoxin protein 4 52 8.1E-13 T 16-09-2016 IPR028037 Antitoxin Rv0909/MT0933 Spa2297_RS08590 46ae00caebd80a974a35c0ebe82742d7 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 2.4E-29 T 16-09-2016 IPR021401 Protein of unknown function DUF3040 Spa2297_RS21170 12e1550331e75d8d5a58df223b89b251 140 Pfam PF07811 TadE-like protein 23 65 3.8E-6 T 16-09-2016 IPR012495 TadE-like Spa2297_RS11455 6df81ea7637fe8f72015c1b5f7100203 439 Pfam PF04932 O-Antigen ligase 204 360 2.8E-14 T 16-09-2016 IPR007016 O-antigen ligase-related Spa2297_RS17945 cd93d9aead2d8f304e67f9991ab6d62e 264 Pfam PF00482 Type II secretion system (T2SS), protein F 123 245 5.0E-12 T 16-09-2016 IPR018076 Type II secretion system F domain Spa2297_RS18540 2db2415f2940ffe11f5af1c209e4d3fe 271 Pfam PF15698 Phosphatase 7 269 3.4E-113 T 16-09-2016 IPR031423 Uncharacterised phosphatase SCO2771 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- Spa2297_RS28565 1b1e6b0792fde7f2714137b2aecfce2e 161 PANTHER PTHR11803:SF2 16 159 4.6E-30 T 16-09-2016 Spa2297_RS28565 1b1e6b0792fde7f2714137b2aecfce2e 161 Gene3D G3DSA:3.30.1330.40 11 159 3.1E-54 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS28565 1b1e6b0792fde7f2714137b2aecfce2e 161 SUPERFAMILY SSF55298 14 159 4.24E-45 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS28565 1b1e6b0792fde7f2714137b2aecfce2e 161 PANTHER PTHR11803 16 159 4.6E-30 T 16-09-2016 IPR006175 YjgF/YER057c/UK114 family Spa2297_RS28565 1b1e6b0792fde7f2714137b2aecfce2e 161 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 16 159 1.8E-26 T 16-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Spa2297_RS13390 31230acd8771b821efc12b1c7d32f112 740 SUPERFAMILY SSF69318 471 713 6.41E-16 T 16-09-2016 Spa2297_RS19950 4e72c5d416962f898e68188efeffb311 401 Pfam PF09594 Protein of unknown function (DUF2029) 68 302 9.9E-16 T 16-09-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 Spa2297_RS07140 3778d6b3069385634f5065d3ace3d6de 260 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 10 249 1.0E-80 T 16-09-2016 Spa2297_RS04945 67ad35d34bb0af367b26619d9e932ff5 127 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 7.5E-41 T 16-09-2016 IPR021398 Protein of unknown function DUF3037 Spa2297_RS18435 4dcaef3c444336fff45a77077890f6a9 270 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 24 268 1.0E-138 T 16-09-2016 Spa2297_RS31235 08b6cb972bb7498d8b9591a73de13ebc 322 Pfam PF05231 MASE1 18 289 2.2E-50 T 16-09-2016 IPR007895 MASE1 Spa2297_RS20335 31bb0d2773b7cb9fdcabd0593e56a412 248 SUPERFAMILY SSF49879 14 85 5.09E-6 T 16-09-2016 IPR008984 SMAD/FHA domain GO:0005515 Spa2297_RS20335 31bb0d2773b7cb9fdcabd0593e56a412 248 Gene3D G3DSA:2.60.200.20 13 89 6.3E-6 T 16-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 Spa2297_RS18665 2e128ef3bf0de416bead23ccbbb0d6e9 277 SUPERFAMILY SSF55608 119 183 4.25E-5 T 16-09-2016 IPR027434 Homing endonuclease GO:0004519 Spa2297_RS09430 8979cdad2b72d17afcb2f2a60c0d9024 265 PANTHER PTHR35864 11 259 3.4E-45 T 16-09-2016 Spa2297_RS14290 73ce1218491ed81646b5923cf6959818 67 Pfam PF04149 Domain of unknown function (DUF397) 6 59 1.5E-21 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS30190 6632f2b8656baf2234559f0f4ce5a6da 75 Pfam PF04149 Domain of unknown function (DUF397) 15 67 2.3E-19 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS02105 dd419151bc4e81c184700a68f86fc0c9 86 Pfam PF17196 Protein of unknown function (DUF5133) 1 64 9.1E-23 T 16-09-2016 IPR033457 Protein of unknown function DUF5133 Spa2297_RS34075 8000475e4e2ba9c61a08e498fd14bb53 94 Pfam PF06224 Winged helix DNA-binding domain 2 94 3.0E-17 T 16-09-2016 IPR009351 Protein of unknown function DUF1006 Spa2297_RS12265 9c8a0767bb899dfa3f33eb7027796a86 420 PANTHER PTHR39639 1 397 6.2E-32 T 16-09-2016 Spa2297_RS12265 9c8a0767bb899dfa3f33eb7027796a86 420 Pfam PF03235 Protein of unknown function DUF262 60 221 7.9E-17 T 16-09-2016 IPR004919 Domain of unknown function DUF262 Spa2297_RS17275 db14b9a4337b581416e7668bac8b9e46 188 Pfam PF10517 Electron transfer DM13 81 185 3.6E-26 T 16-09-2016 IPR019545 DM13 domain Spa2297_RS28645 495780c4c8ddecff546f89626e9cfc29 310 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 30 297 1.8E-26 T 16-09-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Spa2297_RS31305 b0f251e6f26f8ee134cafe5c3d78332c 337 Pfam PF11199 Protein of unknown function (DUF2891) 10 330 1.5E-117 T 16-09-2016 IPR021365 Protein of unknown function DUF2891 Spa2297_RS15545 a52978c33996347e767160aed52dc129 507 SUPERFAMILY SSF52540 246 486 3.93E-6 T 16-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spa2297_RS11660 07d91d9ab2edceb19bf68da79bed4dbb 280 Pfam PF13349 Putative adhesin 18 276 9.0E-13 T 16-09-2016 IPR025164 Putative adhesin Spa2297_RS05720 3b20f4029f39cbed5b745d4263e131f9 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 3.1E-22 T 16-09-2016 IPR007139 Protein of unknown function DUF349 Spa2297_RS05720 3b20f4029f39cbed5b745d4263e131f9 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 9.0E-21 T 16-09-2016 IPR007139 Protein of unknown function DUF349 Spa2297_RS05720 3b20f4029f39cbed5b745d4263e131f9 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 1.6E-11 T 16-09-2016 IPR007139 Protein of unknown function DUF349 Spa2297_RS31485 47e416ce7c9917f7cb7a99062a9b3388 260 Pfam PF05988 Bacterial protein of unknown function (DUF899) 15 207 1.8E-59 T 16-09-2016 IPR010296 Protein of unknown function DUF899, thioredoxin-like Spa2297_RS27755 bea0ce2d35c5d071f998a8db2dbb75e3 218 Pfam PF01381 Helix-turn-helix 89 135 1.8E-8 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS27755 bea0ce2d35c5d071f998a8db2dbb75e3 218 Gene3D G3DSA:1.10.260.40 79 152 7.4E-8 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27755 bea0ce2d35c5d071f998a8db2dbb75e3 218 SUPERFAMILY SSF47413 83 143 1.27E-7 T 16-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 Spa2297_RS27755 bea0ce2d35c5d071f998a8db2dbb75e3 218 SMART SM00530 75 136 1.5E-6 T 16-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spa2297_RS18870 a690828b1c766f814f443ca1bb6b85ec 105 Pfam PF14012 Protein of unknown function (DUF4229) 2 73 1.3E-22 T 16-09-2016 IPR025323 Protein of unknown function DUF4229 Spa2297_RS30200 3e94e8bb611fd585d154cf9f9736823c 147 Gene3D G3DSA:1.25.10.10 11 106 2.6E-4 T 16-09-2016 IPR011989 Armadillo-like helical Spa2297_RS26695 3ca2795f95cb349752b2a8a7699b9ae3 63 SUPERFAMILY SSF53850 3 57 2.82E-5 T 16-09-2016 Spa2297_RS00415 a02d1829fc2c48d1f21b9ad11ef53458 584 Pfam PF01186 Lysyl oxidase 431 566 3.5E-16 T 16-09-2016 IPR001695 Lysyl oxidase GO:0005507|GO:0016641|GO:0055114 Spa2297_RS13265 ab651d22c17d12a1688a9393690549c6 169 Pfam PF04138 GtrA-like protein 14 134 2.9E-22 T 16-09-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 Spa2297_RS03765 16e0318a0742944e6eff06c6cd22a8f3 246 Pfam PF13628 Domain of unknown function (DUF4142) 54 187 1.1E-14 T 16-09-2016 IPR025419 Domain of unknown function DUF4142 Spa2297_RS21310 a4e07cf465659ce6e240098dac7ea6a0 792 Pfam PF02687 FtsX-like permease family 674 782 1.1E-8 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS14295 a864b3250f80519ac1d55554ef0e7e85 170 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 12 159 6.9E-54 T 16-09-2016 IPR018681 Protein of unknown function DUF2165, transmembrane Spa2297_RS22345 d700e7d9709f7ebe20adc9ccc5f80200 263 Pfam PF13672 Protein phosphatase 2C 14 228 1.5E-8 T 16-09-2016 Spa2297_RS17620 f5b923fc0c9ecfb236fe6e4113c87986 407 Pfam PF01757 Acyltransferase family 37 374 6.4E-19 T 16-09-2016 IPR002656 Acyltransferase 3 GO:0016747 Spa2297_RS07990 50520fac69b22cdaa7600cdeea7b5710 159 Pfam PF08592 Domain of unknown function (DUF1772) 22 157 5.7E-16 T 16-09-2016 IPR013901 Protein of unknown function DUF1772 Spa2297_RS22045 672ca31d7707d22613a50b9a85661f58 240 Pfam PF13398 Peptidase M50B-like 30 232 2.7E-62 T 16-09-2016 Spa2297_RS12470 e70d07e33240ce7aaa556e7e44ea987a 202 Pfam PF09438 Domain of unknown function (DUF2017) 9 201 3.0E-59 T 16-09-2016 IPR018561 Domain of unknown function DUF2017 Spa2297_RS11335 c0985c69af55fcbf03596b4972462700 915 Pfam PF02687 FtsX-like permease family 786 898 5.7E-6 T 16-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 Spa2297_RS12395 ac9bf2288f68e5ee12feebeb551eab22 110 Pfam PF12277 Protein of unknown function (DUF3618) 7 52 9.5E-16 T 16-09-2016 IPR022062 Protein of unknown function DUF3618 Spa2297_RS06470 bd2db905cbb8d41cd07b3270a859bc20 276 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 23 276 1.0E-110 T 16-09-2016 IPR022292 Conserved hypothetical protein CHP03843 Spa2297_RS09385 e86c76323283c30cce72a21a3f732169 64 Pfam PF04149 Domain of unknown function (DUF397) 11 60 9.4E-20 T 16-09-2016 IPR007278 Domain of unknown function DUF397 Spa2297_RS23865 6ede2def75bd93a3603c52c02f7468cf 236 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 196 230 0.0017 T 16-09-2016 IPR019931 LPXTG cell wall anchor domain Spa2297_RS07625 d6304ee70dae7271cf5f58b79a8238ef 140 Pfam PF12277 Protein of unknown function (DUF3618) 22 66 1.6E-15 T 16-09-2016 IPR022062 Protein of unknown function DUF3618 Spa2297_RS31800 e926b0df4ec66907df2ed02ffec69a95 455 Pfam PF02706 Chain length determinant protein 4 77 5.6E-8 T 16-09-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020