locus-tag	class	description
OGH68_RS00150	COG0475	glutathione-regulated potassium exporter activity
OGH68_RS00155	COG2235	arginine
OGH68_RS00190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OGH68_RS00200	COG4335	DNA alkylation repair
OGH68_RS00205	COG4589	Belongs to the CDS family
OGH68_RS00210	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OGH68_RS00230	COG0456	acetyltransferase
OGH68_RS00235	COG4221	oxidoreductase activity
OGH68_RS00250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OGH68_RS00345	COG4584	PFAM Integrase catalytic
OGH68_RS00350	COG1484	DNA-dependent DNA replication
OGH68_RS00485	COG2801	Transposase and inactivated derivatives
OGH68_RS00500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OGH68_RS00545	COG1136	(ABC) transporter
OGH68_RS00545	COG0577	efflux transmembrane transporter activity
OGH68_RS00555	COG1653	transport
OGH68_RS00570	COG4585	Histidine kinase
OGH68_RS00605	COG1116	anion transmembrane transporter activity
OGH68_RS00615	COG3842	ATPase activity
OGH68_RS00655	COG0519	Catalyzes the synthesis of GMP from XMP
OGH68_RS00700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OGH68_RS00705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OGH68_RS00710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS00735	COG3387	PFAM Glycoside hydrolase 15-related
OGH68_RS00765	COG1316	TRANSCRIPTIONal
OGH68_RS00795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OGH68_RS00800	COG0110	maltose O-acetyltransferase activity
OGH68_RS00820	COG0640	Transcriptional regulator
OGH68_RS00875	COG4977	sequence-specific DNA binding
OGH68_RS00880	COG2318	DinB family
OGH68_RS00890	COG1007	ATP synthesis coupled electron transport
OGH68_RS00900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OGH68_RS00905	COG0713	ATP synthesis coupled electron transport
OGH68_RS00915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OGH68_RS00925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS00935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OGH68_RS00945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OGH68_RS00975	COG1175	transmembrane transport
OGH68_RS00985	COG1609	Transcriptional regulator
OGH68_RS00990	COG1609	Transcriptional regulator
OGH68_RS01000	COG1621	beta-fructofuranosidase activity
OGH68_RS01005	COG1609	Transcriptional regulator
OGH68_RS01030	COG1621	beta-fructofuranosidase activity
OGH68_RS01050	COG1278	Cold shock
OGH68_RS01070	COG4335	DNA alkylation repair
OGH68_RS01095	COG0513	Belongs to the DEAD box helicase family
OGH68_RS01115	COG1755	Isoprenylcysteine carboxyl methyltransferase
OGH68_RS01140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OGH68_RS01145	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OGH68_RS01150	COG3896	Chloramphenicol phosphotransferase-like protein
OGH68_RS01165	COG1295	ribonuclease BN
OGH68_RS01175	COG2130	NADP-dependent
OGH68_RS01190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGH68_RS01195	COG0569	domain protein
OGH68_RS01245	COG1881	PFAM PEBP family protein
OGH68_RS01260	COG2318	DinB family
OGH68_RS01340	COG0583	DNA-binding transcription factor activity
OGH68_RS01435	COG1573	uracil-dna glycosylase
OGH68_RS01460	COG3290	protein histidine kinase activity
OGH68_RS01485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OGH68_RS01545	COG1024	Enoyl-CoA hydratase
OGH68_RS01570	COG2124	cytochrome p450
OGH68_RS01575	COG2124	cytochrome p450
OGH68_RS01580	COG2124	cytochrome p450
OGH68_RS01590	COG3401	FG-GAP repeat protein
OGH68_RS01605	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS01610	COG0387	Pfam Sodium calcium exchanger
OGH68_RS01620	COG2070	2-Nitropropane dioxygenase
OGH68_RS01625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OGH68_RS01635	COG0515	serine threonine protein kinase
OGH68_RS01655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OGH68_RS01660	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS01665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OGH68_RS01670	COG1024	Enoyl-CoA hydratase
OGH68_RS01675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OGH68_RS01695	COG3285	dna ligase
OGH68_RS01695	COG1793	dna ligase
OGH68_RS01700	COG3958	Transketolase
OGH68_RS01705	COG1252	NADH dehydrogenase
OGH68_RS01730	COG0517	IMP dehydrogenase activity
OGH68_RS01735	COG0693	protein deglycase activity
OGH68_RS01760	COG2205	protein histidine kinase activity
OGH68_RS01760	COG0784	Response regulator, receiver
OGH68_RS01770	COG1191	sigma factor activity
OGH68_RS01840	COG2264	protein methyltransferase activity
OGH68_RS01900	COG1937	Protein conserved in bacteria
OGH68_RS01910	COG0517	IMP dehydrogenase activity
OGH68_RS01910	COG0516	GMP reductase activity
OGH68_RS01935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OGH68_RS01940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OGH68_RS01955	COG1349	DNA-binding transcription factor activity
OGH68_RS01960	COG0726	polysaccharide deacetylase
OGH68_RS01975	COG0300	oxidoreductase activity
OGH68_RS01985	COG0243	molybdopterin cofactor binding
OGH68_RS01990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OGH68_RS02020	COG0009	L-threonylcarbamoyladenylate synthase
OGH68_RS02025	COG0702	epimerase
OGH68_RS02030	COG1733	regulation of RNA biosynthetic process
OGH68_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS02065	COG1024	Enoyl-CoA hydratase
OGH68_RS02070	COG0183	Belongs to the thiolase family
OGH68_RS02075	COG1309	transcriptional regulator
OGH68_RS02080	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS02085	COG1024	Enoyl-CoA hydratase
OGH68_RS02090	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS02100	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS02105	COG1609	Transcriptional regulator
OGH68_RS02125	COG1172	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS02130	COG1172	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS02140	COG1129	ABC transporter
OGH68_RS02150	COG3347	Dehydrogenase
OGH68_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS02155	COG1070	Carbohydrate kinase
OGH68_RS02160	COG0247	lactate metabolic process
OGH68_RS02165	COG1139	Iron-sulfur cluster binding protein
OGH68_RS02170	COG1556	Lactate utilization protein
OGH68_RS02175	COG0328	RNA-DNA hybrid ribonuclease activity
OGH68_RS02190	COG1172	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS02200	COG1129	ABC transporter
OGH68_RS02205	COG1879	ABC-type sugar transport system periplasmic component
OGH68_RS02215	COG2208	phosphoserine phosphatase activity
OGH68_RS02215	COG2770	Histidine kinase
OGH68_RS02270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS02280	COG1802	Transcriptional regulator
OGH68_RS02285	COG2271	Major facilitator Superfamily
OGH68_RS02290	COG0745	RESPONSE REGULATOR receiver
OGH68_RS02295	COG2205	protein histidine kinase activity
OGH68_RS02305	COG0477	Major facilitator Superfamily
OGH68_RS02320	COG2814	Major facilitator Superfamily
OGH68_RS02330	COG0288	reversible hydration of carbon dioxide
OGH68_RS02390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OGH68_RS02400	COG0589	response to stress
OGH68_RS02430	COG2376	Dihydroxyacetone kinase
OGH68_RS02435	COG1461	Dihydroxyacetone kinase
OGH68_RS02440	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OGH68_RS02445	COG0310	cobalt ion transport
OGH68_RS02450	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
OGH68_RS02460	COG1122	ATPase activity
OGH68_RS02465	COG2217	Heavy metal translocating P-type atpase
OGH68_RS02470	COG0640	Transcriptional regulator
OGH68_RS02510	COG0363	glucosamine-6-phosphate deaminase activity
OGH68_RS02525	COG1335	isochorismatase
OGH68_RS02530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS02570	COG1716	ATPase activity
OGH68_RS02570	COG0842	Transport permease protein
OGH68_RS02570	COG1131	(ABC) transporter
OGH68_RS02605	COG0667	Aldo Keto reductase
OGH68_RS02630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS02630	COG0723	plastoquinol--plastocyanin reductase activity
OGH68_RS02635	COG2080	2 iron, 2 sulfur cluster binding
OGH68_RS02640	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OGH68_RS02645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OGH68_RS02705	COG1472	Belongs to the glycosyl hydrolase 3 family
OGH68_RS02715	COG1175	transmembrane transport
OGH68_RS02725	COG1609	Transcriptional regulator
OGH68_RS02750	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS02750	COG2208	phosphoserine phosphatase activity
OGH68_RS02750	COG2172	sigma factor antagonist activity
OGH68_RS02790	COG0028	Belongs to the TPP enzyme family
OGH68_RS02820	COG2208	phosphoserine phosphatase activity
OGH68_RS02820	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS02820	COG2172	sigma factor antagonist activity
OGH68_RS02860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS02910	COG1686	Belongs to the peptidase S11 family
OGH68_RS02915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OGH68_RS02925	COG4948	Mandelate Racemase Muconate Lactonizing
OGH68_RS02940	COG0395	ABC-type sugar transport system, permease component
OGH68_RS02945	COG1175	transmembrane transport
OGH68_RS02965	COG3386	PFAM SMP-30 Gluconolaconase
OGH68_RS02970	COG1414	Transcriptional regulator
OGH68_RS02980	COG4213	ABC transporter substrate-binding protein
OGH68_RS02990	COG4214	carbohydrate transport
OGH68_RS03005	COG2132	Multicopper oxidase
OGH68_RS03020	COG3903	Transcriptional regulator
OGH68_RS03020	COG3629	intracellular signal transduction
OGH68_RS03050	COG0395	ABC-type sugar transport system, permease component
OGH68_RS03055	COG1175	transmembrane transport
OGH68_RS03080	COG1175	transmembrane transport
OGH68_RS03085	COG0395	ABC-type sugar transport system, permease component
OGH68_RS03120	COG2197	response regulator
OGH68_RS03125	COG4585	Histidine kinase
OGH68_RS03130	COG1136	(ABC) transporter
OGH68_RS03130	COG0577	efflux transmembrane transporter activity
OGH68_RS03165	COG1940	carbohydrate kinase activity
OGH68_RS03175	COG1175	transmembrane transport
OGH68_RS03180	COG0395	ABC-type sugar transport system, permease component
OGH68_RS03185	COG2723	6-phospho-beta-galactosidase activity
OGH68_RS03190	COG0477	Major facilitator Superfamily
OGH68_RS03195	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OGH68_RS03200	COG1032	radical SAM domain protein
OGH68_RS03215	COG0783	Belongs to the Dps family
OGH68_RS03235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OGH68_RS03245	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS03250	COG1320	monovalent cation:proton antiporter activity
OGH68_RS03265	COG0651	ATP synthesis coupled electron transport
OGH68_RS03270	COG1006	Multisubunit Na H antiporter MnhC subunit
OGH68_RS03275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OGH68_RS03275	COG2111	Na H antiporter
OGH68_RS03285	COG5006	permease, DMT superfamily
OGH68_RS03305	COG0435	Glutathione S-transferase
OGH68_RS03325	COG1937	Protein conserved in bacteria
OGH68_RS03345	COG0500	methyltransferase
OGH68_RS03365	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS03370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGH68_RS03410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS03415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OGH68_RS03420	COG0736	holo-[acyl-carrier-protein] synthase activity
OGH68_RS03435	COG4106	trans-aconitate 2-methyltransferase activity
OGH68_RS03445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OGH68_RS03450	COG0626	cystathionine gamma-synthase activity
OGH68_RS03490	COG0590	tRNA wobble adenosine to inosine editing
OGH68_RS03505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OGH68_RS03535	COG0702	epimerase
OGH68_RS03575	COG1131	(ABC) transporter
OGH68_RS03595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OGH68_RS03610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OGH68_RS03665	COG0431	NADPH-dependent FMN reductase
OGH68_RS03710	COG4948	Mandelate Racemase Muconate Lactonizing
OGH68_RS03850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OGH68_RS03865	COG0009	L-threonylcarbamoyladenylate synthase
OGH68_RS03870	COG0288	reversible hydration of carbon dioxide
OGH68_RS03910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OGH68_RS03930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGH68_RS03935	COG1349	DNA-binding transcription factor activity
OGH68_RS03940	COG1063	alcohol dehydrogenase
OGH68_RS03950	COG0395	ABC-type sugar transport system, permease component
OGH68_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS04045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OGH68_RS04080	COG1349	DNA-binding transcription factor activity
OGH68_RS04110	COG0577	efflux transmembrane transporter activity
OGH68_RS04115	COG0577	efflux transmembrane transporter activity
OGH68_RS04115	COG1136	(ABC) transporter
OGH68_RS04140	COG1940	carbohydrate kinase activity
OGH68_RS04145	COG2223	nitrite transmembrane transporter activity
OGH68_RS04160	COG0539	negative regulation of cytoplasmic translation
OGH68_RS04170	COG2197	response regulator
OGH68_RS04175	COG4585	Histidine kinase
OGH68_RS04200	COG1660	Displays ATPase and GTPase activities
OGH68_RS04225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OGH68_RS04245	COG0204	Acyl-transferase
OGH68_RS04275	COG0584	glycerophosphoryl diester phosphodiesterase
OGH68_RS04295	COG0671	phosphoesterase, PA-phosphatase related
OGH68_RS04305	COG1309	transcriptional regulator
OGH68_RS04325	COG0640	Transcriptional regulator
OGH68_RS04330	COG1902	pentaerythritol trinitrate reductase activity
OGH68_RS04340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OGH68_RS04355	COG2706	6-phosphogluconolactonase activity
OGH68_RS04405	COG0500	methyltransferase
OGH68_RS04410	COG4981	capsule polysaccharide biosynthetic process
OGH68_RS04430	COG2835	tetraacyldisaccharide 4'-kinase activity
OGH68_RS04445	COG0596	Alpha beta hydrolase
OGH68_RS04450	COG2770	Histidine kinase
OGH68_RS04450	COG2208	phosphoserine phosphatase activity
OGH68_RS04470	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OGH68_RS04515	COG3940	Belongs to the glycosyl hydrolase 43 family
OGH68_RS04520	COG3940	Belongs to the glycosyl hydrolase 43 family
OGH68_RS04535	COG2072	flavoprotein involved in K transport
OGH68_RS04545	COG1132	(ABC) transporter
OGH68_RS04555	COG1132	(ABC) transporter
OGH68_RS04560	COG1132	(ABC) transporter
OGH68_RS04575	COG1946	Acyl-CoA thioesterase
OGH68_RS04580	COG0386	Belongs to the glutathione peroxidase family
OGH68_RS04585	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS04595	COG0242	peptide deformylase activity
OGH68_RS04605	COG3442	glutamine amidotransferase
OGH68_RS04610	COG0205	6-phosphofructokinase activity
OGH68_RS04650	COG1957	nucleoside hydrolase
OGH68_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS04705	COG0204	Acyl-transferase
OGH68_RS04710	COG0829	nickel cation binding
OGH68_RS04715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OGH68_RS04720	COG0830	nickel cation binding
OGH68_RS04725	COG0804	urea catabolic process
OGH68_RS04730	COG0832	Belongs to the urease beta subunit family
OGH68_RS04735	COG0831	urea catabolic process
OGH68_RS04740	COG1309	transcriptional regulator
OGH68_RS04755	COG0740	serine-type endopeptidase activity
OGH68_RS04770	COG1280	lysine exporter protein (LysE YggA)
OGH68_RS04775	COG0583	DNA-binding transcription factor activity
OGH68_RS04790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OGH68_RS04795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OGH68_RS04800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OGH68_RS04855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OGH68_RS04880	COG1940	carbohydrate kinase activity
OGH68_RS04885	COG2188	Transcriptional regulator
OGH68_RS04890	COG1595	DNA-templated transcription, initiation
OGH68_RS04930	COG0626	cystathionine gamma-synthase activity
OGH68_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS04970	COG1522	sequence-specific DNA binding
OGH68_RS04975	COG0419	ATPase involved in DNA repair
OGH68_RS04980	COG0420	3'-5' exonuclease activity
OGH68_RS04985	COG1739	Uncharacterized protein family UPF0029
OGH68_RS04990	COG1832	CoA-binding protein
OGH68_RS05010	COG0110	maltose O-acetyltransferase activity
OGH68_RS05015	COG2124	cytochrome p450
OGH68_RS05025	COG2318	DinB family
OGH68_RS05045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OGH68_RS05055	COG1968	undecaprenyl-diphosphatase activity
OGH68_RS05100	COG0667	Aldo Keto reductase
OGH68_RS05120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OGH68_RS05125	COG1132	(ABC) transporter
OGH68_RS05130	COG1132	(ABC) transporter
OGH68_RS05145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05170	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS05195	COG3321	synthase
OGH68_RS05195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05195	COG0300	oxidoreductase activity
OGH68_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS05205	COG2124	cytochrome p450
OGH68_RS05240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS05255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OGH68_RS05290	COG2801	Transposase and inactivated derivatives
OGH68_RS05335	COG2813	Specifically methylates the guanine in position
OGH68_RS05345	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OGH68_RS05350	COG0673	inositol 2-dehydrogenase activity
OGH68_RS05365	COG2318	DinB family
OGH68_RS05375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OGH68_RS05430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OGH68_RS05440	COG0659	secondary active sulfate transmembrane transporter activity
OGH68_RS05450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OGH68_RS05480	COG0583	DNA-binding transcription factor activity
OGH68_RS05520	COG1695	Transcriptional regulator
OGH68_RS05550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OGH68_RS05550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OGH68_RS05600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OGH68_RS05640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OGH68_RS05655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OGH68_RS05660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OGH68_RS05675	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OGH68_RS05695	COG2018	Roadblock/LC7 domain
OGH68_RS05735	COG2814	Major facilitator Superfamily
OGH68_RS05740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OGH68_RS05750	COG1984	allophanate hydrolase subunit 2
OGH68_RS05765	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS05770	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OGH68_RS05810	COG2270	Major facilitator Superfamily
OGH68_RS05820	COG3030	protein affecting phage T7 exclusion by the F plasmid
OGH68_RS05825	COG1216	Glycosyl transferase, family 2
OGH68_RS05850	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS05890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OGH68_RS05895	COG0140	phosphoribosyl-ATP diphosphatase activity
OGH68_RS05900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OGH68_RS05905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OGH68_RS05905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OGH68_RS05910	COG3201	nicotinamide mononucleotide transporter
OGH68_RS05935	COG1846	Transcriptional regulator
OGH68_RS05935	COG1940	carbohydrate kinase activity
OGH68_RS05940	COG0738	Major facilitator superfamily
OGH68_RS05945	COG2233	PERMEase
OGH68_RS05960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGH68_RS05970	COG0531	amino acid
OGH68_RS05980	COG1191	sigma factor activity
OGH68_RS05990	COG2390	Transcriptional regulator
OGH68_RS05995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OGH68_RS06005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OGH68_RS06020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OGH68_RS06045	COG0284	orotidine-5'-phosphate decarboxylase activity
OGH68_RS06050	COG0167	dihydroorotate dehydrogenase activity
OGH68_RS06055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OGH68_RS06060	COG0505	Belongs to the CarA family
OGH68_RS06070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OGH68_RS06075	COG0540	Belongs to the ATCase OTCase family
OGH68_RS06080	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OGH68_RS06090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OGH68_RS06095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OGH68_RS06100	COG0006	proline dipeptidase activity
OGH68_RS06110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OGH68_RS06115	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OGH68_RS06120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OGH68_RS06125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OGH68_RS06135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OGH68_RS06145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OGH68_RS06150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OGH68_RS06170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OGH68_RS06190	COG0124	histidyl-tRNA synthetase
OGH68_RS06205	COG1196	nuclear chromosome segregation
OGH68_RS06210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OGH68_RS06215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OGH68_RS06220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGH68_RS06225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGH68_RS06235	COG2255	four-way junction helicase activity
OGH68_RS06240	COG0632	four-way junction helicase activity
OGH68_RS06245	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OGH68_RS06250	COG0217	transcriptional regulatory protein
OGH68_RS06255	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OGH68_RS06260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OGH68_RS06270	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS06275	COG1560	Kdo2-lipid A biosynthetic process
OGH68_RS06280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OGH68_RS06300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OGH68_RS06315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OGH68_RS06375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OGH68_RS06380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OGH68_RS06440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OGH68_RS06440	COG1648	precorrin-2 dehydrogenase activity
OGH68_RS06445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OGH68_RS06460	COG1464	Belongs to the NlpA lipoprotein family
OGH68_RS06465	COG2011	ABC-type metal ion transport system permease component
OGH68_RS06500	COG0584	glycerophosphoryl diester phosphodiesterase
OGH68_RS06505	COG0204	Acyl-transferase
OGH68_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS06510	COG0477	Major facilitator Superfamily
OGH68_RS06520	COG3629	intracellular signal transduction
OGH68_RS06530	COG1819	glycosyl
OGH68_RS06535	COG0165	Argininosuccinate lyase
OGH68_RS06540	COG0137	argininosuccinate synthase activity
OGH68_RS06550	COG1438	arginine binding
OGH68_RS06555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS06560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OGH68_RS06565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OGH68_RS06570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OGH68_RS06575	COG2207	Transcriptional regulator
OGH68_RS06575	COG3708	Transcriptional regulator
OGH68_RS06610	COG0697	spore germination
OGH68_RS06620	COG1649	PFAM Uncharacterised BCR, COG1649
OGH68_RS06630	COG1051	belongs to the nudix hydrolase family
OGH68_RS06640	COG0072	phenylalanine-tRNA ligase activity
OGH68_RS06640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGH68_RS06645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OGH68_RS06650	COG5002	protein histidine kinase activity
OGH68_RS06655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OGH68_RS06660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OGH68_RS06665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OGH68_RS06670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OGH68_RS06705	COG0697	spore germination
OGH68_RS06725	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS06730	COG0174	glutamine synthetase
OGH68_RS06735	COG2186	Transcriptional regulator
OGH68_RS06740	COG0531	amino acid
OGH68_RS06745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OGH68_RS06775	COG0517	IMP dehydrogenase activity
OGH68_RS06775	COG4175	Glycine betaine
OGH68_RS06780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OGH68_RS06790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OGH68_RS06795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OGH68_RS06815	COG0805	protein transport
OGH68_RS06820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OGH68_RS06855	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OGH68_RS06865	COG1609	Transcriptional regulator
OGH68_RS06870	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OGH68_RS06875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OGH68_RS06885	COG4122	O-methyltransferase activity
OGH68_RS06890	COG1222	aaa ATPase
OGH68_RS06910	COG1994	Peptidase M50
OGH68_RS06910	COG0517	IMP dehydrogenase activity
OGH68_RS06920	COG2197	response regulator
OGH68_RS06925	COG0747	negative chemotaxis
OGH68_RS06935	COG0646	methionine synthase
OGH68_RS06935	COG1410	methionine synthase
OGH68_RS06940	COG1414	Transcriptional regulator
OGH68_RS06945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OGH68_RS06950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OGH68_RS06955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OGH68_RS06960	COG2186	Transcriptional regulator
OGH68_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS06970	COG4948	Mandelate Racemase Muconate Lactonizing
OGH68_RS06990	COG0215	cysteine-tRNA ligase activity
OGH68_RS07005	COG0588	phosphoglycerate mutase activity
OGH68_RS07010	COG0598	Magnesium transport protein CorA
OGH68_RS07025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS07030	COG0667	Aldo Keto reductase
OGH68_RS07065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGH68_RS07085	COG0564	pseudouridine synthase activity
OGH68_RS07100	COG2186	Transcriptional regulator
OGH68_RS07105	COG3265	gluconokinase activity
OGH68_RS07135	COG3573	Dehydrogenase
OGH68_RS07140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OGH68_RS07145	COG2149	membrane
OGH68_RS07165	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS07175	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS07185	COG3876	Protein conserved in bacteria
OGH68_RS07200	COG0789	Transcriptional regulator
OGH68_RS07215	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS07225	COG0640	Transcriptional regulator
OGH68_RS07235	COG0477	Major facilitator Superfamily
OGH68_RS07250	COG3842	ATPase activity
OGH68_RS07270	COG2851	Citrate transporter
OGH68_RS07275	COG0243	molybdopterin cofactor binding
OGH68_RS07285	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OGH68_RS07290	COG2188	Transcriptional regulator
OGH68_RS07310	COG0515	serine threonine protein kinase
OGH68_RS07310	COG2815	serine threonine protein kinase
OGH68_RS07315	COG2755	lipolytic protein G-D-S-L family
OGH68_RS07330	COG0726	polysaccharide deacetylase
OGH68_RS07330	COG1649	PFAM Uncharacterised BCR, COG1649
OGH68_RS07340	COG1725	Transcriptional regulator
OGH68_RS07370	COG4565	transcriptional regulatory protein
OGH68_RS07415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OGH68_RS07420	COG0587	DNA-directed DNA polymerase activity
OGH68_RS07425	COG0477	Major facilitator Superfamily
OGH68_RS07450	COG3629	intracellular signal transduction
OGH68_RS07450	COG3903	Transcriptional regulator
OGH68_RS07465	COG0641	radical SAM
OGH68_RS07500	COG1799	cell septum assembly
OGH68_RS07505	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS07510	COG0477	Major facilitator Superfamily
OGH68_RS07515	COG0671	phosphoesterase, PA-phosphatase related
OGH68_RS07530	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS07570	COG1160	GTP binding
OGH68_RS07580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OGH68_RS07610	COG3541	Predicted nucleotidyltransferase
OGH68_RS07635	COG1187	pseudouridine synthase activity
OGH68_RS07640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OGH68_RS07645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OGH68_RS07660	COG0686	Belongs to the AlaDH PNT family
OGH68_RS07670	COG0494	nUDIX hydrolase
OGH68_RS07675	COG0504	CTP synthase activity
OGH68_RS07680	COG3387	PFAM Glycoside hydrolase 15-related
OGH68_RS07695	COG0497	DNA recombination
OGH68_RS07700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OGH68_RS07720	COG1120	ATPase activity
OGH68_RS07725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS07730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS07735	COG0647	UMP catabolic process
OGH68_RS07770	COG2094	Belongs to the DNA glycosylase MPG family
OGH68_RS07780	COG1881	PFAM PEBP family protein
OGH68_RS07805	COG1119	ATPase activity
OGH68_RS07820	COG2197	response regulator
OGH68_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS07835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OGH68_RS07845	COG0842	Transport permease protein
OGH68_RS07845	COG1131	(ABC) transporter
OGH68_RS07845	COG1716	ATPase activity
OGH68_RS07850	COG3830	Belongs to the UPF0237 family
OGH68_RS07850	COG0560	Phosphoserine phosphatase
OGH68_RS07870	COG2807	transmembrane transport
OGH68_RS07875	COG2186	Transcriptional regulator
OGH68_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS07905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OGH68_RS07925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OGH68_RS07930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS07945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OGH68_RS07970	COG3387	PFAM Glycoside hydrolase 15-related
OGH68_RS08010	COG1024	Enoyl-CoA hydratase
OGH68_RS08020	COG0488	(ABC) transporter
OGH68_RS08040	COG0235	Class ii aldolase
OGH68_RS08055	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OGH68_RS08060	COG1492	cobalamin metabolic process
OGH68_RS08075	COG1797	cobyrinic acid a,c-diamide synthase activity
OGH68_RS08105	COG1104	cysteine desulfurase activity
OGH68_RS08120	COG1917	Cupin 2, conserved barrel domain protein
OGH68_RS08140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OGH68_RS08170	COG1414	Transcriptional regulator
OGH68_RS08185	COG4585	Histidine kinase
OGH68_RS08190	COG2197	response regulator
OGH68_RS08195	COG0768	penicillin binding
OGH68_RS08205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OGH68_RS08210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS08250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OGH68_RS08280	COG2171	N-acyltransferase activity
OGH68_RS08300	COG0822	iron-sulfur transferase activity
OGH68_RS08305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OGH68_RS08310	COG0396	ATPase activity
OGH68_RS08320	COG0719	Fe-S assembly protein
OGH68_RS08365	COG0109	protoheme IX farnesyltransferase activity
OGH68_RS08375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OGH68_RS08390	COG0363	glucosamine-6-phosphate deaminase activity
OGH68_RS08405	COG0166	Belongs to the GPI family
OGH68_RS08415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OGH68_RS08420	COG0149	triose-phosphate isomerase activity
OGH68_RS08425	COG0126	phosphoglycerate kinase activity
OGH68_RS08430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OGH68_RS08440	COG1481	regulation of sporulation
OGH68_RS08445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OGH68_RS08450	COG1660	Displays ATPase and GTPase activities
OGH68_RS08455	COG0322	excinuclease ABC activity
OGH68_RS08470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OGH68_RS08505	COG0556	nucleotide-excision repair
OGH68_RS08515	COG0584	glycerophosphoryl diester phosphodiesterase
OGH68_RS08520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OGH68_RS08525	COG0477	Major facilitator Superfamily
OGH68_RS08530	COG2313	pseudouridylate synthase activity
OGH68_RS08560	COG0402	S-adenosylhomocysteine deaminase activity
OGH68_RS08575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OGH68_RS08595	COG0237	dephospho-CoA kinase activity
OGH68_RS08610	COG2226	methyltransferase
OGH68_RS08615	COG1643	Atp-dependent helicase
OGH68_RS08650	COG2050	protein possibly involved in aromatic compounds catabolism
OGH68_RS08705	COG0737	Belongs to the 5'-nucleotidase family
OGH68_RS08725	COG1605	Chorismate mutase
OGH68_RS08725	COG0287	Prephenate dehydrogenase
OGH68_RS08760	COG0513	Belongs to the DEAD box helicase family
OGH68_RS08765	COG1278	Cold shock
OGH68_RS08790	COG0070	glutamate synthase
OGH68_RS08790	COG0069	glutamate synthase activity
OGH68_RS08790	COG0067	glutamate synthase
OGH68_RS08820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS08825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OGH68_RS08835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OGH68_RS08845	COG0159	tryptophan synthase activity
OGH68_RS08850	COG0133	tryptophan synthase activity
OGH68_RS08855	COG0134	indole-3-glycerol-phosphate synthase activity
OGH68_RS08880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OGH68_RS08890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS08895	COG2508	Transcriptional regulator
OGH68_RS08910	COG0107	imidazoleglycerol-phosphate synthase activity
OGH68_RS08915	COG0251	oxidation-reduction process
OGH68_RS08920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OGH68_RS08925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OGH68_RS08935	COG0131	Imidazoleglycerol-phosphate dehydratase
OGH68_RS08940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OGH68_RS08945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OGH68_RS08985	COG1432	Conserved Protein
OGH68_RS08995	COG0587	DNA-directed DNA polymerase activity
OGH68_RS09035	COG0454	-acetyltransferase
OGH68_RS09045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OGH68_RS09055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OGH68_RS09060	COG3599	regulation of cell shape
OGH68_RS09070	COG1799	cell septum assembly
OGH68_RS09075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OGH68_RS09080	COG1496	oxidoreductase activity
OGH68_RS09090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OGH68_RS09095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OGH68_RS09105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OGH68_RS09110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OGH68_RS09120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OGH68_RS09135	COG0275	rRNA processing
OGH68_RS09145	COG0714	Associated with various cellular activities
OGH68_RS09165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OGH68_RS09175	COG1126	abc transporter atp-binding protein
OGH68_RS09185	COG1309	transcriptional regulator
OGH68_RS09210	COG0352	thiamine-phosphate diphosphorylase activity
OGH68_RS09220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS09225	COG2022	thiamine diphosphate biosynthetic process
OGH68_RS09225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS09235	COG2022	thiamine diphosphate biosynthetic process
OGH68_RS09240	COG0515	serine threonine protein kinase
OGH68_RS09240	COG2815	serine threonine protein kinase
OGH68_RS09245	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OGH68_RS09255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OGH68_RS09260	COG2193	ferroxidase activity
OGH68_RS09270	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OGH68_RS09280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OGH68_RS09285	COG0205	6-phosphofructokinase activity
OGH68_RS09295	COG4585	Histidine kinase
OGH68_RS09320	COG1940	carbohydrate kinase activity
OGH68_RS09330	COG0003	Pfam Anion-transporting ATPase
OGH68_RS09350	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS09400	COG2205	protein histidine kinase activity
OGH68_RS09405	COG0745	RESPONSE REGULATOR receiver
OGH68_RS09415	COG1929	Belongs to the glycerate kinase type-1 family
OGH68_RS09420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OGH68_RS09425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OGH68_RS09430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OGH68_RS09435	COG0723	plastoquinol--plastocyanin reductase activity
OGH68_RS09440	COG2010	Cytochrome c
OGH68_RS09445	COG1845	cytochrome c oxidase, subunit III
OGH68_RS09455	COG1376	ErfK ybiS ycfS ynhG family protein
OGH68_RS09465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OGH68_RS09470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OGH68_RS09475	COG1104	cysteine desulfurase activity
OGH68_RS09480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS09500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OGH68_RS09505	COG2197	response regulator
OGH68_RS09510	COG4585	Histidine kinase
OGH68_RS09535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OGH68_RS09550	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OGH68_RS09555	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OGH68_RS09555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OGH68_RS09570	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OGH68_RS09580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OGH68_RS09585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OGH68_RS09590	COG0508	dehydrogenase complex catalyzes the overall conversion of
OGH68_RS09600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OGH68_RS09610	COG0733	neurotransmitter:sodium symporter activity
OGH68_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS09645	COG2409	Drug exporters of the RND superfamily
OGH68_RS09670	COG0321	lipoyl(octanoyl) transferase activity
OGH68_RS09675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OGH68_RS09690	COG1714	RDD family
OGH68_RS09755	COG2197	response regulator
OGH68_RS09770	COG2365	Tyrosine phosphatase family
OGH68_RS09810	COG1609	Transcriptional regulator
OGH68_RS09820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OGH68_RS09840	COG2226	methyltransferase
OGH68_RS09860	COG0174	glutamine synthetase
OGH68_RS09890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OGH68_RS09890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGH68_RS09895	COG2814	Major facilitator Superfamily
OGH68_RS09905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OGH68_RS09945	COG1994	Peptidase M50
OGH68_RS09980	COG5398	heme oxygenase
OGH68_RS09990	COG0672	)-iron permease
OGH68_RS10015	COG2814	Major facilitator Superfamily
OGH68_RS10055	COG3540	Alkaline phosphatase
OGH68_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS10090	COG0789	Transcriptional regulator
OGH68_RS10105	COG3022	response to hydroperoxide
OGH68_RS10110	COG0800	Aldolase
OGH68_RS10125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OGH68_RS10130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OGH68_RS10140	COG1595	DNA-templated transcription, initiation
OGH68_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS10155	COG2030	dehydratase
OGH68_RS10160	COG4585	Histidine kinase
OGH68_RS10165	COG2197	response regulator
OGH68_RS10175	COG0183	Belongs to the thiolase family
OGH68_RS10195	COG0860	N-Acetylmuramoyl-L-alanine amidase
OGH68_RS10210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS10230	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS10235	COG1309	transcriptional regulator
OGH68_RS10270	COG3845	ABC transporter
OGH68_RS10280	COG0183	Belongs to the thiolase family
OGH68_RS10285	COG2124	cytochrome p450
OGH68_RS10310	COG4122	O-methyltransferase activity
OGH68_RS10350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGH68_RS10360	COG0390	transport system, permease component
OGH68_RS10405	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OGH68_RS10485	COG2226	methyltransferase
OGH68_RS10530	COG3547	Transposase (IS116 IS110 IS902 family)
OGH68_RS10535	COG2801	Transposase and inactivated derivatives
OGH68_RS10535	COG3415	Transposase
OGH68_RS10620	COG0582	viral genome integration into host DNA
OGH68_RS10655	COG4585	Histidine kinase
OGH68_RS10660	COG0586	Pfam SNARE associated Golgi protein
OGH68_RS10670	COG1358	cellular component organization or biogenesis
OGH68_RS10715	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OGH68_RS10720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OGH68_RS10735	COG0477	Major facilitator Superfamily
OGH68_RS10740	COG1309	transcriptional regulator
OGH68_RS10755	COG4585	Histidine kinase
OGH68_RS10760	COG2197	response regulator
OGH68_RS10775	COG0667	Aldo Keto reductase
OGH68_RS10780	COG0789	Transcriptional regulator
OGH68_RS10800	COG2205	protein histidine kinase activity
OGH68_RS10805	COG0745	RESPONSE REGULATOR receiver
OGH68_RS10870	COG1741	Belongs to the pirin family
OGH68_RS10885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OGH68_RS10890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGH68_RS10895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OGH68_RS10935	COG1764	response to oxidative stress
OGH68_RS10940	COG2130	NADP-dependent
OGH68_RS10965	COG1077	Cell shape determining protein MreB Mrl
OGH68_RS10980	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS10985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OGH68_RS10985	COG0825	malonyl-CoA metabolic process
OGH68_RS11025	COG2814	Major facilitator Superfamily
OGH68_RS11055	COG1335	isochorismatase
OGH68_RS11155	COG1487	ribonuclease activity
OGH68_RS11185	COG1070	Carbohydrate kinase
OGH68_RS11200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OGH68_RS11205	COG0358	DNA primase activity
OGH68_RS11215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OGH68_RS11240	COG0243	molybdopterin cofactor binding
OGH68_RS11300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS11305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS11305	COG2146	nitrite reductase [NAD(P)H] activity
OGH68_RS11330	COG0574	Belongs to the PEP-utilizing enzyme family
OGH68_RS11330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OGH68_RS11345	COG0667	Aldo Keto reductase
OGH68_RS11360	COG0423	glycine-tRNA ligase activity
OGH68_RS11365	COG0803	Belongs to the bacterial solute-binding protein 9 family
OGH68_RS11365	COG3443	Belongs to the bacterial solute-binding protein 9 family
OGH68_RS11370	COG1121	(ABC) transporter
OGH68_RS11375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OGH68_RS11390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OGH68_RS11395	COG1381	Involved in DNA repair and RecF pathway recombination
OGH68_RS11435	COG2197	response regulator
OGH68_RS11440	COG4585	Histidine kinase
OGH68_RS11445	COG2409	Drug exporters of the RND superfamily
OGH68_RS11455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OGH68_RS11470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OGH68_RS11500	COG2315	Protein conserved in bacteria
OGH68_RS11510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OGH68_RS11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS11535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OGH68_RS11540	COG1234	tRNA 3'-trailer cleavage
OGH68_RS11545	COG0537	adenosine 5'-monophosphoramidase activity
OGH68_RS11550	COG0793	Belongs to the peptidase S41A family
OGH68_RS11550	COG4946	Tricorn protease homolog
OGH68_RS11575	COG0484	heat shock protein binding
OGH68_RS11580	COG1420	regulation of RNA biosynthetic process
OGH68_RS11610	COG0481	GTPase activity
OGH68_RS11615	COG0268	Binds directly to 16S ribosomal RNA
OGH68_RS11640	COG1234	tRNA 3'-trailer cleavage
OGH68_RS11645	COG1555	photosystem II stabilization
OGH68_RS11650	COG1307	EDD domain protein, DegV family
OGH68_RS11660	COG0495	leucyl-tRNA aminoacylation
OGH68_RS11690	COG0588	phosphoglycerate mutase activity
OGH68_RS11695	COG0799	negative regulation of ribosome biogenesis
OGH68_RS11705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OGH68_RS11715	COG0501	Belongs to the peptidase M48B family
OGH68_RS11730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OGH68_RS11740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OGH68_RS11780	COG1215	transferase activity, transferring glycosyl groups
OGH68_RS11795	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS11800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OGH68_RS11805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OGH68_RS11810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OGH68_RS11815	COG1530	ribonuclease E activity
OGH68_RS11865	COG0772	Belongs to the SEDS family
OGH68_RS11870	COG0768	penicillin binding
OGH68_RS11885	COG1077	Cell shape determining protein MreB Mrl
OGH68_RS11890	COG0105	UTP biosynthetic process
OGH68_RS11900	COG0285	dihydrofolate synthase activity
OGH68_RS11905	COG0525	valine-tRNA ligase activity
OGH68_RS11915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OGH68_RS11920	COG0740	serine-type endopeptidase activity
OGH68_RS11925	COG0740	serine-type endopeptidase activity
OGH68_RS11930	COG0544	peptidyl-prolyl cis-trans isomerase activity
OGH68_RS11950	COG3594	Acyltransferase
OGH68_RS11955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OGH68_RS11965	COG4552	Acetyltransferase involved in intracellular survival and related
OGH68_RS11985	COG1113	amino acid transport
OGH68_RS11990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OGH68_RS11995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OGH68_RS12040	COG5002	protein histidine kinase activity
OGH68_RS12060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OGH68_RS12065	COG2124	cytochrome p450
OGH68_RS12105	COG0668	transmembrane transport
OGH68_RS12110	COG1940	carbohydrate kinase activity
OGH68_RS12115	COG1653	transport
OGH68_RS12120	COG1175	transmembrane transport
OGH68_RS12125	COG0395	ABC-type sugar transport system, permease component
OGH68_RS12130	COG1486	melibiose metabolic process
OGH68_RS12145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS12195	COG0577	efflux transmembrane transporter activity
OGH68_RS12195	COG1136	(ABC) transporter
OGH68_RS12220	COG0629	single-stranded DNA binding
OGH68_RS12285	COG1131	(ABC) transporter
OGH68_RS12300	COG3962	Belongs to the TPP enzyme family
OGH68_RS12305	COG3718	enzyme involved in inositol metabolism
OGH68_RS12315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS12340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OGH68_RS12415	COG2115	Belongs to the xylose isomerase family
OGH68_RS12425	COG0673	inositol 2-dehydrogenase activity
OGH68_RS12430	COG1609	Transcriptional regulator
OGH68_RS12445	COG0456	acetyltransferase
OGH68_RS12445	COG1846	Transcriptional regulator
OGH68_RS12465	COG1472	Belongs to the glycosyl hydrolase 3 family
OGH68_RS12485	COG2310	stress, protein
OGH68_RS12495	COG1131	(ABC) transporter
OGH68_RS12500	COG4585	Histidine kinase
OGH68_RS12505	COG2197	response regulator
OGH68_RS12510	COG0028	Belongs to the TPP enzyme family
OGH68_RS12520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS12535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OGH68_RS12605	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS12610	COG1946	Acyl-CoA thioesterase
OGH68_RS12620	COG4585	Histidine kinase
OGH68_RS12625	COG2197	response regulator
OGH68_RS12640	COG1309	transcriptional regulator
OGH68_RS12645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS12660	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS12690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OGH68_RS12700	COG0589	response to stress
OGH68_RS12710	COG4977	sequence-specific DNA binding
OGH68_RS12715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OGH68_RS12740	COG3979	chitinase
OGH68_RS12750	COG0745	RESPONSE REGULATOR receiver
OGH68_RS12775	COG0406	alpha-ribazole phosphatase activity
OGH68_RS12825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS12845	COG0154	amidase activity
OGH68_RS12855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS12860	COG0765	amino acid transport
OGH68_RS12865	COG0765	amino acid transport
OGH68_RS12870	COG1126	abc transporter atp-binding protein
OGH68_RS12940	COG0673	inositol 2-dehydrogenase activity
OGH68_RS12945	COG4702	Belongs to the UPF0303 family
OGH68_RS12955	COG1742	UPF0060 membrane protein
OGH68_RS12960	COG0706	membrane insertase activity
OGH68_RS12960	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
OGH68_RS12970	COG4213	ABC transporter substrate-binding protein
OGH68_RS12975	COG3764	Sortase (surface protein transpeptidase)
OGH68_RS13025	COG1074	ATP-dependent DNA helicase activity
OGH68_RS13080	COG2733	membrane
OGH68_RS13095	COG4555	ABC transporter
OGH68_RS13110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OGH68_RS13120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OGH68_RS13155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OGH68_RS13165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OGH68_RS13175	COG1263	PTS System
OGH68_RS13180	COG1263	PTS System
OGH68_RS13185	COG1234	tRNA 3'-trailer cleavage
OGH68_RS13210	COG1113	amino acid transport
OGH68_RS13215	COG1115	amino acid carrier protein
OGH68_RS13225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OGH68_RS13235	COG1335	isochorismatase
OGH68_RS13270	COG0277	FAD linked oxidase domain protein
OGH68_RS13290	COG5002	protein histidine kinase activity
OGH68_RS13295	COG0745	RESPONSE REGULATOR receiver
OGH68_RS13300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OGH68_RS13340	COG3654	unkown
OGH68_RS13415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OGH68_RS13420	COG0395	ABC-type sugar transport system, permease component
OGH68_RS13440	COG1678	Uncharacterized ACR, COG1678
OGH68_RS13445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OGH68_RS13450	COG0776	regulation of translation
OGH68_RS13460	COG3973	AAA domain
OGH68_RS13485	COG2223	nitrite transmembrane transporter activity
OGH68_RS13500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OGH68_RS13505	COG0793	Belongs to the peptidase S41A family
OGH68_RS13515	COG2884	Cell division ATP-binding protein ftsE
OGH68_RS13530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OGH68_RS13535	COG0515	serine threonine protein kinase
OGH68_RS13540	COG0515	serine threonine protein kinase
OGH68_RS13550	COG1653	transport
OGH68_RS13555	COG1175	transmembrane transport
OGH68_RS13560	COG0395	ABC-type sugar transport system, permease component
OGH68_RS13565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OGH68_RS13570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OGH68_RS13590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OGH68_RS13595	COG1309	transcriptional regulator
OGH68_RS13605	COG1134	teichoic acid transport
OGH68_RS13605	COG1388	LysM domain
OGH68_RS13615	COG2902	Dehydrogenase
OGH68_RS13640	COG0653	protein targeting
OGH68_RS13650	COG3214	Protein conserved in bacteria
OGH68_RS13655	COG2197	response regulator
OGH68_RS13660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OGH68_RS13670	COG0823	Involved in the tonB-independent uptake of proteins
OGH68_RS13675	COG5000	phosphorelay sensor kinase activity
OGH68_RS13675	COG5002	protein histidine kinase activity
OGH68_RS13680	COG0745	RESPONSE REGULATOR receiver
OGH68_RS13685	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OGH68_RS13705	COG0714	Associated with various cellular activities
OGH68_RS13745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OGH68_RS13750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OGH68_RS13750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OGH68_RS13750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OGH68_RS13755	COG0681	Belongs to the peptidase S26 family
OGH68_RS13765	COG1482	cell wall glycoprotein biosynthetic process
OGH68_RS13775	COG2835	tetraacyldisaccharide 4'-kinase activity
OGH68_RS13780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OGH68_RS13815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OGH68_RS13820	COG0778	Nitroreductase
OGH68_RS13820	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
OGH68_RS13845	COG1316	TRANSCRIPTIONal
OGH68_RS13850	COG1316	TRANSCRIPTIONal
OGH68_RS13875	COG1316	TRANSCRIPTIONal
OGH68_RS13880	COG0181	hydroxymethylbilane synthase activity
OGH68_RS13955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OGH68_RS13980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OGH68_RS13995	COG2205	protein histidine kinase activity
OGH68_RS14000	COG0745	RESPONSE REGULATOR receiver
OGH68_RS14005	COG3104	oligopeptide transport
OGH68_RS14035	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS14040	COG1191	sigma factor activity
OGH68_RS14045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OGH68_RS14080	COG1794	racemase activity, acting on amino acids and derivatives
OGH68_RS14090	COG1228	amidohydrolase
OGH68_RS14100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGH68_RS14105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OGH68_RS14160	COG2755	lipolytic protein G-D-S-L family
OGH68_RS14165	COG0183	Belongs to the thiolase family
OGH68_RS14195	COG1136	(ABC) transporter
OGH68_RS14195	COG0577	efflux transmembrane transporter activity
OGH68_RS14200	COG0577	efflux transmembrane transporter activity
OGH68_RS14200	COG1136	(ABC) transporter
OGH68_RS14205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OGH68_RS14210	COG1252	NADH dehydrogenase
OGH68_RS14255	COG0148	phosphopyruvate hydratase activity
OGH68_RS14270	COG2124	cytochrome p450
OGH68_RS14340	COG0789	Transcriptional regulator
OGH68_RS14375	COG0577	efflux transmembrane transporter activity
OGH68_RS14380	COG1136	(ABC) transporter
OGH68_RS14385	COG2814	Major facilitator Superfamily
OGH68_RS14405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS14445	COG4585	Histidine kinase
OGH68_RS14455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OGH68_RS14460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OGH68_RS14465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OGH68_RS14470	COG0193	aminoacyl-tRNA hydrolase activity
OGH68_RS14485	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OGH68_RS14500	COG4106	trans-aconitate 2-methyltransferase activity
OGH68_RS14505	COG1846	Transcriptional regulator
OGH68_RS14510	COG2197	response regulator
OGH68_RS14515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OGH68_RS14550	COG0488	(ABC) transporter
OGH68_RS14560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OGH68_RS14565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OGH68_RS14575	COG0084	hydrolase, TatD family'
OGH68_RS14625	COG3739	integral membrane protein
OGH68_RS14635	COG0442	prolyl-tRNA aminoacylation
OGH68_RS14645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OGH68_RS14650	COG1764	response to oxidative stress
OGH68_RS14660	COG1122	ATPase activity
OGH68_RS14670	COG0310	cobalt ion transport
OGH68_RS14680	COG2409	Drug exporters of the RND superfamily
OGH68_RS14690	COG4946	Tricorn protease homolog
OGH68_RS14690	COG0793	Belongs to the peptidase S41A family
OGH68_RS14700	COG2072	flavoprotein involved in K transport
OGH68_RS14705	COG2267	carboxylic ester hydrolase activity
OGH68_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS14865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGH68_RS14875	COG1309	transcriptional regulator
OGH68_RS14895	COG3152	Membrane
OGH68_RS14900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OGH68_RS14905	COG2188	Transcriptional regulator
OGH68_RS14965	COG0582	viral genome integration into host DNA
OGH68_RS14985	COG0521	Mo-molybdopterin cofactor biosynthetic process
OGH68_RS15000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OGH68_RS15005	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OGH68_RS15030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OGH68_RS15040	COG1970	mechanosensitive ion channel activity
OGH68_RS15060	COG0477	Major facilitator Superfamily
OGH68_RS15075	COG1247	-acetyltransferase
OGH68_RS15080	COG3384	dioxygenase
OGH68_RS15085	COG1846	Transcriptional regulator
OGH68_RS15135	COG0582	viral genome integration into host DNA
OGH68_RS15375	COG1686	Belongs to the peptidase S11 family
OGH68_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS15420	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OGH68_RS15465	COG0531	amino acid
OGH68_RS15510	COG0726	polysaccharide deacetylase
OGH68_RS15525	COG2205	protein histidine kinase activity
OGH68_RS15555	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS15580	COG1309	transcriptional regulator
OGH68_RS15620	COG0259	pyridoxamine-phosphate oxidase activity
OGH68_RS15635	COG2072	flavoprotein involved in K transport
OGH68_RS15645	COG1024	Enoyl-CoA hydratase
OGH68_RS15650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OGH68_RS15675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OGH68_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS15695	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS15700	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS15710	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS15750	COG1653	transport
OGH68_RS15785	COG1131	(ABC) transporter
OGH68_RS15795	COG0596	Alpha beta hydrolase
OGH68_RS15795	COG2945	thiolester hydrolase activity
OGH68_RS15810	COG4821	SIS domain
OGH68_RS15825	COG4555	ABC transporter
OGH68_RS15840	COG0259	pyridoxamine-phosphate oxidase activity
OGH68_RS15870	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS15880	COG0439	Biotin carboxylase
OGH68_RS15885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS15900	COG5006	permease, DMT superfamily
OGH68_RS15905	COG0583	DNA-binding transcription factor activity
OGH68_RS15915	COG0247	lactate metabolic process
OGH68_RS15915	COG0277	FAD linked oxidase domain protein
OGH68_RS15925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OGH68_RS15960	COG4106	trans-aconitate 2-methyltransferase activity
OGH68_RS15975	COG0596	Alpha beta hydrolase
OGH68_RS16030	COG2356	endonuclease I
OGH68_RS16035	COG0667	Aldo Keto reductase
OGH68_RS16060	COG2252	PERMEase
OGH68_RS16070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OGH68_RS16165	COG2814	Major facilitator Superfamily
OGH68_RS16175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OGH68_RS16180	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OGH68_RS16200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS16205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS16210	COG1120	ATPase activity
OGH68_RS16215	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OGH68_RS16230	COG1061	Type III restriction enzyme res subunit
OGH68_RS16240	COG3973	AAA domain
OGH68_RS16280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OGH68_RS16310	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OGH68_RS16315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OGH68_RS16410	COG1115	amino acid carrier protein
OGH68_RS16435	COG0463	Glycosyl transferase, family 2
OGH68_RS16450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OGH68_RS16455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGH68_RS16455	COG1877	trehalose-phosphatase activity
OGH68_RS16470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OGH68_RS16480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OGH68_RS16485	COG1105	Belongs to the carbohydrate kinase PfkB family
OGH68_RS16520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OGH68_RS16540	COG2197	response regulator
OGH68_RS16570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS16580	COG3842	ATPase activity
OGH68_RS16590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OGH68_RS16600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OGH68_RS16605	COG0215	cysteine-tRNA ligase activity
OGH68_RS16610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OGH68_RS16615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OGH68_RS16620	COG1329	Transcriptional regulator
OGH68_RS16635	COG5002	protein histidine kinase activity
OGH68_RS16675	COG0588	phosphoglycerate mutase activity
OGH68_RS16685	COG0477	Major facilitator Superfamily
OGH68_RS16695	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS16745	COG1733	regulation of RNA biosynthetic process
OGH68_RS16760	COG0667	Aldo Keto reductase
OGH68_RS16765	COG3973	AAA domain
OGH68_RS16800	COG2188	Transcriptional regulator
OGH68_RS16820	COG4552	Acetyltransferase involved in intracellular survival and related
OGH68_RS16835	COG1490	D-aminoacyl-tRNA deacylase activity
OGH68_RS16840	COG0354	folic acid binding
OGH68_RS16850	COG3485	protocatechuate 3,4-dioxygenase
OGH68_RS16885	COG2897	thiosulfate sulfurtransferase activity
OGH68_RS16910	COG0745	RESPONSE REGULATOR receiver
OGH68_RS16915	COG1609	Transcriptional regulator
OGH68_RS16920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OGH68_RS16925	COG0745	RESPONSE REGULATOR receiver
OGH68_RS16940	COG0823	Involved in the tonB-independent uptake of proteins
OGH68_RS16945	COG0737	Belongs to the 5'-nucleotidase family
OGH68_RS16960	COG0456	acetyltransferase
OGH68_RS16965	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OGH68_RS16975	COG0494	nUDIX hydrolase
OGH68_RS16975	COG0406	alpha-ribazole phosphatase activity
OGH68_RS16980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OGH68_RS16995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OGH68_RS17000	COG0306	phosphate transporter
OGH68_RS17010	COG1937	Protein conserved in bacteria
OGH68_RS17030	COG0277	FAD linked oxidase domain protein
OGH68_RS17035	COG0671	phosphoesterase, PA-phosphatase related
OGH68_RS17040	COG0739	heme binding
OGH68_RS17040	COG0741	lytic transglycosylase activity
OGH68_RS17040	COG1196	nuclear chromosome segregation
OGH68_RS17045	COG3903	Transcriptional regulator
OGH68_RS17045	COG3629	intracellular signal transduction
OGH68_RS17060	COG0736	holo-[acyl-carrier-protein] synthase activity
OGH68_RS17065	COG1607	acyl-coa hydrolase
OGH68_RS17080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OGH68_RS17085	COG1917	Cupin 2, conserved barrel domain protein
OGH68_RS17095	COG5285	phytanoyl-CoA dioxygenase
OGH68_RS17195	COG1131	(ABC) transporter
OGH68_RS17205	COG4585	Histidine kinase
OGH68_RS17210	COG2197	response regulator
OGH68_RS17245	COG1252	NADH dehydrogenase
OGH68_RS17270	COG0579	oxidoreductase
OGH68_RS17275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OGH68_RS17285	COG0739	heme binding
OGH68_RS17285	COG1196	nuclear chromosome segregation
OGH68_RS17285	COG0741	lytic transglycosylase activity
OGH68_RS17365	COG0513	Belongs to the DEAD box helicase family
OGH68_RS17375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OGH68_RS17380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OGH68_RS17410	COG0785	Cytochrome C biogenesis protein
OGH68_RS17415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OGH68_RS17415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OGH68_RS17425	COG1643	Atp-dependent helicase
OGH68_RS17450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OGH68_RS17460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OGH68_RS17490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OGH68_RS17495	COG0047	phosphoribosylformylglycinamidine synthase activity
OGH68_RS17500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OGH68_RS17530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OGH68_RS17545	COG0151	Belongs to the GarS family
OGH68_RS17570	COG1505	serine-type exopeptidase activity
OGH68_RS17615	COG2197	response regulator
OGH68_RS17620	COG4585	Histidine kinase
OGH68_RS17630	COG1131	(ABC) transporter
OGH68_RS17690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OGH68_RS17725	COG1191	sigma factor activity
OGH68_RS17730	COG1191	sigma factor activity
OGH68_RS17760	COG3467	pyridoxamine 5'-phosphate
OGH68_RS17775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OGH68_RS17785	COG2205	protein histidine kinase activity
OGH68_RS17790	COG0745	RESPONSE REGULATOR receiver
OGH68_RS17800	COG1404	Belongs to the peptidase S8 family
OGH68_RS17870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OGH68_RS17870	COG4651	solute:proton antiporter activity
OGH68_RS17900	COG2197	response regulator
OGH68_RS17915	COG3387	PFAM Glycoside hydrolase 15-related
OGH68_RS17925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OGH68_RS17950	COG2267	carboxylic ester hydrolase activity
OGH68_RS18040	COG2188	Transcriptional regulator
OGH68_RS18115	COG0784	Response regulator, receiver
OGH68_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS18125	COG1595	DNA-templated transcription, initiation
OGH68_RS18200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OGH68_RS18215	COG0653	protein targeting
OGH68_RS18235	COG0006	proline dipeptidase activity
OGH68_RS18255	COG1999	signal sequence binding
OGH68_RS18265	COG2372	response to copper ion
OGH68_RS18270	COG2837	iron assimilation
OGH68_RS18280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OGH68_RS18285	COG0561	phosphatase activity
OGH68_RS18310	COG1131	(ABC) transporter
OGH68_RS18320	COG0789	Transcriptional regulator
OGH68_RS18325	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OGH68_RS18335	COG0561	phosphatase activity
OGH68_RS18340	COG0739	heme binding
OGH68_RS18340	COG1196	nuclear chromosome segregation
OGH68_RS18340	COG0741	lytic transglycosylase activity
OGH68_RS18345	COG4988	ABC transporter
OGH68_RS18350	COG1294	oxidase, subunit
OGH68_RS18355	COG1271	oxidase subunit
OGH68_RS18370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OGH68_RS18375	COG1609	Transcriptional regulator
OGH68_RS18395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OGH68_RS18420	COG0662	Cupin 2, conserved barrel domain protein
OGH68_RS18425	COG1950	PFAM Membrane protein of
OGH68_RS18430	COG0626	cystathionine gamma-synthase activity
OGH68_RS18480	COG0305	Participates in initiation and elongation during chromosome replication
OGH68_RS18485	COG0534	Mate efflux family protein
OGH68_RS18490	COG0359	binds to the 23S rRNA
OGH68_RS18495	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OGH68_RS18500	COG0629	single-stranded DNA binding
OGH68_RS18505	COG0360	Binds together with S18 to 16S ribosomal RNA
OGH68_RS18530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OGH68_RS18555	COG0617	tRNA 3'-terminal CCA addition
OGH68_RS18570	COG2815	serine threonine protein kinase
OGH68_RS18570	COG0515	serine threonine protein kinase
OGH68_RS18575	COG1595	DNA-templated transcription, initiation
OGH68_RS18585	COG0492	ferredoxin-NADP+ reductase activity
OGH68_RS18590	COG3118	belongs to the thioredoxin family
OGH68_RS18605	COG1192	Involved in chromosome partitioning
OGH68_RS18610	COG0357	Ribosomal RNA small subunit methyltransferase G
OGH68_RS18620	COG0706	membrane insertase activity
OGH68_RS18625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OGH68_RS18630	COG0594	ribonuclease P activity
OGH68_RS18635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OGH68_RS18645	COG0592	DNA-directed DNA polymerase activity
OGH68_RS18650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OGH68_RS18655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OGH68_RS18660	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
OGH68_RS18670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OGH68_RS18695	COG0515	serine threonine protein kinase
OGH68_RS18725	COG0457	Tetratricopeptide repeat
OGH68_RS18725	COG0705	Rhomboid family
OGH68_RS18740	COG3764	Sortase (surface protein transpeptidase)
OGH68_RS18755	COG3764	Sortase (surface protein transpeptidase)
OGH68_RS18760	COG3764	Sortase (surface protein transpeptidase)
OGH68_RS18765	COG0515	serine threonine protein kinase
OGH68_RS18770	COG0768	penicillin binding
OGH68_RS18785	COG1716	ATPase activity
OGH68_RS18790	COG1716	ATPase activity
OGH68_RS18810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OGH68_RS18820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OGH68_RS18825	COG2151	metal-sulfur cluster biosynthetic enzyme
OGH68_RS18830	COG3396	Phenylacetate-CoA oxygenase
OGH68_RS18835	COG3460	Phenylacetate-CoA oxygenase
OGH68_RS18840	COG3396	Phenylacetate-CoA oxygenase
OGH68_RS18865	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS18870	COG1309	transcriptional regulator
OGH68_RS18875	COG1522	sequence-specific DNA binding
OGH68_RS18905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OGH68_RS18925	COG1136	(ABC) transporter
OGH68_RS18925	COG4591	ABC-type transport system involved in lipoprotein release permease component
OGH68_RS18945	COG0515	serine threonine protein kinase
OGH68_RS18950	COG0515	serine threonine protein kinase
OGH68_RS18970	COG0022	dehydrogenase e1 component
OGH68_RS18975	COG0508	dehydrogenase complex catalyzes the overall conversion of
OGH68_RS19005	COG2271	Major facilitator Superfamily
OGH68_RS19035	COG1362	aminopeptidase activity
OGH68_RS19045	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS19070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OGH68_RS19075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGH68_RS19105	COG1289	transmembrane transporter activity
OGH68_RS19155	COG0446	pyridine nucleotide-disulphide oxidoreductase
OGH68_RS19155	COG1902	pentaerythritol trinitrate reductase activity
OGH68_RS19215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OGH68_RS19240	COG0492	ferredoxin-NADP+ reductase activity
OGH68_RS19245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OGH68_RS19255	COG0798	PFAM Bile acid sodium symporter
OGH68_RS19260	COG2072	flavoprotein involved in K transport
OGH68_RS19265	COG0640	Transcriptional regulator
OGH68_RS19270	COG0492	ferredoxin-NADP+ reductase activity
OGH68_RS19305	COG0513	Belongs to the DEAD box helicase family
OGH68_RS19310	COG1278	Cold shock
OGH68_RS19320	COG0747	negative chemotaxis
OGH68_RS19370	COG0583	DNA-binding transcription factor activity
OGH68_RS19375	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS19385	COG0601	transmembrane transport
OGH68_RS19390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS19420	COG3938	Belongs to the proline racemase family
OGH68_RS19505	COG0717	Belongs to the dCTP deaminase family
OGH68_RS19520	COG2181	nitrate reductase activity
OGH68_RS19520	COG0247	lactate metabolic process
OGH68_RS19530	COG0443	Heat shock 70 kDa protein
OGH68_RS19535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OGH68_RS19540	COG0484	heat shock protein binding
OGH68_RS19545	COG0789	Transcriptional regulator
OGH68_RS19575	COG0542	response to heat
OGH68_RS19600	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OGH68_RS19615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OGH68_RS19620	COG0191	fructose-bisphosphate aldolase activity
OGH68_RS19625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OGH68_RS19630	COG0477	Major facilitator Superfamily
OGH68_RS19650	COG3844	kynureninase activity
OGH68_RS19665	COG4585	Histidine kinase
OGH68_RS19670	COG2197	response regulator
OGH68_RS19675	COG2124	cytochrome p450
OGH68_RS19680	COG3559	Exporter of polyketide antibiotics
OGH68_RS19685	COG1131	(ABC) transporter
OGH68_RS19710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OGH68_RS19795	COG0693	protein deglycase activity
OGH68_RS19810	COG1802	Transcriptional regulator
OGH68_RS19815	COG0463	Glycosyl transferase, family 2
OGH68_RS19835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OGH68_RS19840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OGH68_RS19865	COG1595	DNA-templated transcription, initiation
OGH68_RS19990	COG1408	metallophosphoesterase
OGH68_RS20005	COG1610	YqeY-like protein
OGH68_RS20010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OGH68_RS20020	COG0003	Pfam Anion-transporting ATPase
OGH68_RS20045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OGH68_RS20075	COG2267	carboxylic ester hydrolase activity
OGH68_RS20085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OGH68_RS20090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OGH68_RS20155	COG1205	dead DEAH box helicase
OGH68_RS20155	COG1111	helicase
OGH68_RS20160	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS20165	COG2172	sigma factor antagonist activity
OGH68_RS20170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OGH68_RS20180	COG2890	protein-(glutamine-N5) methyltransferase activity
OGH68_RS20190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OGH68_RS20190	COG1754	DNA topoisomerase type I activity
OGH68_RS20195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OGH68_RS20200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OGH68_RS20260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OGH68_RS20260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OGH68_RS20280	COG1136	(ABC) transporter
OGH68_RS20280	COG0577	efflux transmembrane transporter activity
OGH68_RS20300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OGH68_RS20305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OGH68_RS20310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OGH68_RS20315	COG0254	rRNA binding
OGH68_RS20325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OGH68_RS20345	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS20350	COG2318	DinB family
OGH68_RS20365	COG0076	glutamate decarboxylase activity
OGH68_RS20370	COG0789	Transcriptional regulator
OGH68_RS20380	COG1595	DNA-templated transcription, initiation
OGH68_RS20395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OGH68_RS20400	COG2027	D-alanyl-D-alanine carboxypeptidase
OGH68_RS20410	COG0037	tRNA processing
OGH68_RS20425	COG0302	gtp cyclohydrolase
OGH68_RS20435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OGH68_RS20440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OGH68_RS20455	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OGH68_RS20455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OGH68_RS20475	COG1174	glycine betaine transport
OGH68_RS20490	COG0649	NAD binding
OGH68_RS20505	COG2197	response regulator
OGH68_RS20510	COG0640	Transcriptional regulator
OGH68_RS20530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OGH68_RS20535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OGH68_RS20545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OGH68_RS20565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OGH68_RS20590	COG2027	D-alanyl-D-alanine carboxypeptidase
OGH68_RS20600	COG2205	protein histidine kinase activity
OGH68_RS20605	COG0745	RESPONSE REGULATOR receiver
OGH68_RS20615	COG1595	DNA-templated transcription, initiation
OGH68_RS20620	COG1194	a g-specific adenine glycosylase
OGH68_RS20625	COG0671	phosphoesterase, PA-phosphatase related
OGH68_RS20635	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OGH68_RS20655	COG0248	Ppx GppA phosphatase
OGH68_RS20660	COG1082	Xylose isomerase domain protein TIM barrel
OGH68_RS20670	COG0129	dihydroxy-acid dehydratase activity
OGH68_RS20680	COG4991	sh3 domain protein
OGH68_RS20690	COG1129	ABC transporter
OGH68_RS20690	COG0842	Transport permease protein
OGH68_RS20700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OGH68_RS20705	COG0180	Tryptophanyl-tRNA synthetase
OGH68_RS20725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGH68_RS20730	COG2223	nitrite transmembrane transporter activity
OGH68_RS20735	COG0123	including yeast histone deacetylase and acetoin utilization protein
OGH68_RS20770	COG1595	DNA-templated transcription, initiation
OGH68_RS20785	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OGH68_RS20790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OGH68_RS20795	COG0181	hydroxymethylbilane synthase activity
OGH68_RS20800	COG1648	precorrin-2 dehydrogenase activity
OGH68_RS20800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OGH68_RS20805	COG2226	methyltransferase
OGH68_RS20810	COG0113	porphobilinogen synthase activity
OGH68_RS20815	COG1309	transcriptional regulator
OGH68_RS20885	COG0018	arginyl-trna synthetase
OGH68_RS20890	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OGH68_RS20910	COG1690	Belongs to the RtcB family
OGH68_RS20985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OGH68_RS20990	COG0406	alpha-ribazole phosphatase activity
OGH68_RS21000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OGH68_RS21005	COG0785	Cytochrome C biogenesis protein
OGH68_RS21010	COG1333	cytochrome c biogenesis protein
OGH68_RS21015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OGH68_RS21035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OGH68_RS21045	COG0109	protoheme IX farnesyltransferase activity
OGH68_RS21050	COG4941	Belongs to the sigma-70 factor family
OGH68_RS21055	COG3795	YCII-related domain
OGH68_RS21065	COG0163	prenyltransferase activity
OGH68_RS21080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OGH68_RS21090	COG1301	dicarboxylic acid transport
OGH68_RS21095	COG1309	transcriptional regulator
OGH68_RS21110	COG0183	Belongs to the thiolase family
OGH68_RS21120	COG1278	Cold shock
OGH68_RS21125	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OGH68_RS21140	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OGH68_RS21150	COG2226	methyltransferase
OGH68_RS21155	COG2066	Belongs to the glutaminase family
OGH68_RS21215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21225	COG0649	NAD binding
OGH68_RS21235	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OGH68_RS21240	COG1034	ATP synthesis coupled electron transport
OGH68_RS21250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OGH68_RS21255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21265	COG0713	ATP synthesis coupled electron transport
OGH68_RS21270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OGH68_RS21280	COG1007	ATP synthesis coupled electron transport
OGH68_RS21310	COG0142	geranyltranstransferase activity
OGH68_RS21370	COG2234	aminopeptidase activity
OGH68_RS21370	COG4935	Belongs to the peptidase S8 family
OGH68_RS21400	COG1013	pyruvate-flavodoxin oxidoreductase activity
OGH68_RS21405	COG0674	pyruvate-flavodoxin oxidoreductase activity
OGH68_RS21405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OGH68_RS21425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OGH68_RS21445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OGH68_RS21450	COG0839	Belongs to the complex I subunit 6 family
OGH68_RS21455	COG0713	ATP synthesis coupled electron transport
OGH68_RS21470	COG1007	ATP synthesis coupled electron transport
OGH68_RS21475	COG0501	Belongs to the peptidase M48B family
OGH68_RS21480	COG3304	Inner membrane component domain
OGH68_RS21490	COG2261	transglycosylase associated protein
OGH68_RS21500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OGH68_RS21505	COG1666	GTP binding
OGH68_RS21575	COG4974	Belongs to the 'phage' integrase family
OGH68_RS21610	COG0402	S-adenosylhomocysteine deaminase activity
OGH68_RS21625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OGH68_RS21630	COG2030	dehydratase
OGH68_RS21640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OGH68_RS21655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OGH68_RS21660	COG0436	Aminotransferase
OGH68_RS21680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OGH68_RS21690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OGH68_RS21695	COG0222	ribosome binding
OGH68_RS21700	COG0085	RNA polymerase activity
OGH68_RS21705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OGH68_RS21720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OGH68_RS21725	COG0049	tRNA binding
OGH68_RS21730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OGH68_RS21735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OGH68_RS21775	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS21780	COG0515	serine threonine protein kinase
OGH68_RS21795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OGH68_RS21810	COG0516	GMP reductase activity
OGH68_RS21820	COG1595	DNA-templated transcription, initiation
OGH68_RS21835	COG0583	DNA-binding transcription factor activity
OGH68_RS21845	COG2132	Multicopper oxidase
OGH68_RS21850	COG4221	oxidoreductase activity
OGH68_RS21870	COG0726	polysaccharide deacetylase
OGH68_RS21885	COG4941	Belongs to the sigma-70 factor family
OGH68_RS21900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OGH68_RS21925	COG0802	atpase or kinase
OGH68_RS21935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OGH68_RS21945	COG0736	holo-[acyl-carrier-protein] synthase activity
OGH68_RS21950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OGH68_RS21970	COG1072	(Pantothenic acid kinase))
OGH68_RS21975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OGH68_RS21980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OGH68_RS21985	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OGH68_RS21990	COG0488	(ABC) transporter
OGH68_RS22000	COG0101	tRNA pseudouridine synthase activity
OGH68_RS22005	COG0203	ribosomal protein L17
OGH68_RS22010	COG0202	RNA polymerase activity
OGH68_RS22015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OGH68_RS22020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OGH68_RS22025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OGH68_RS22030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OGH68_RS22040	COG0563	adenylate kinase activity
OGH68_RS22065	COG0200	Binds to the 23S rRNA
OGH68_RS22070	COG1841	ribosomal large subunit assembly
OGH68_RS22075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OGH68_RS22080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OGH68_RS22085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OGH68_RS22090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OGH68_RS22095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OGH68_RS22100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OGH68_RS22105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OGH68_RS22110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OGH68_RS22115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OGH68_RS22120	COG0255	Belongs to the universal ribosomal protein uL29 family
OGH68_RS22125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OGH68_RS22130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OGH68_RS22135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OGH68_RS22140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OGH68_RS22145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OGH68_RS22150	COG0089	rRNA binding
OGH68_RS22155	COG0088	Forms part of the polypeptide exit tunnel
OGH68_RS22160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OGH68_RS22165	COG0051	transcription antitermination factor activity, RNA binding
OGH68_RS22240	COG0519	Catalyzes the synthesis of GMP from XMP
OGH68_RS22240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OGH68_RS22270	COG2197	response regulator
OGH68_RS22300	COG0739	heme binding
OGH68_RS22315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS22335	COG0714	Associated with various cellular activities
OGH68_RS22340	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OGH68_RS22345	COG3552	Protein containing von Willebrand factor type A (VWA) domain
OGH68_RS22350	COG0045	succinate-CoA ligase (ADP-forming) activity
OGH68_RS22380	COG0138	bifunctional purine biosynthesis protein purh
OGH68_RS22400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OGH68_RS22410	COG0538	isocitrate dehydrogenase activity
OGH68_RS22415	COG0039	L-malate dehydrogenase activity
OGH68_RS22445	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS22455	COG4175	Glycine betaine
OGH68_RS22455	COG0517	IMP dehydrogenase activity
OGH68_RS22460	COG4176	ABC-type proline glycine betaine transport system permease component
OGH68_RS22475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGH68_RS22480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OGH68_RS22485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS22490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS22495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OGH68_RS22510	COG1595	DNA-templated transcription, initiation
OGH68_RS22515	COG0180	Tryptophanyl-tRNA synthetase
OGH68_RS22530	COG1686	Belongs to the peptidase S11 family
OGH68_RS22540	COG1408	metallophosphoesterase
OGH68_RS22545	COG1309	transcriptional regulator
OGH68_RS22580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OGH68_RS22585	COG1053	succinate dehydrogenase
OGH68_RS22595	COG2009	succinate dehydrogenase
OGH68_RS22735	COG1595	DNA-templated transcription, initiation
OGH68_RS22750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS22750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS22760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OGH68_RS22785	COG1216	Glycosyl transferase, family 2
OGH68_RS22800	COG2089	acid synthase
OGH68_RS22810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OGH68_RS22810	COG1473	amidohydrolase
OGH68_RS22815	COG1744	ABC transporter substrate-binding protein PnrA-like
OGH68_RS22820	COG3845	ABC transporter
OGH68_RS22830	COG1079	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS22850	COG1132	(ABC) transporter
OGH68_RS22860	COG1131	(ABC) transporter
OGH68_RS22875	COG0612	Peptidase, M16
OGH68_RS22900	COG4566	intracellular signal transduction
OGH68_RS22910	COG2814	Major facilitator Superfamily
OGH68_RS22915	COG0583	DNA-binding transcription factor activity
OGH68_RS22930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OGH68_RS22960	COG2205	protein histidine kinase activity
OGH68_RS22965	COG0745	RESPONSE REGULATOR receiver
OGH68_RS22970	COG1595	DNA-templated transcription, initiation
OGH68_RS22990	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS23005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OGH68_RS23045	COG4770	biotin carboxylase activity
OGH68_RS23055	COG0424	maF-like protein
OGH68_RS23065	COG1309	transcriptional regulator
OGH68_RS23080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS23095	COG1024	Enoyl-CoA hydratase
OGH68_RS23105	COG2986	histidine ammonia-lyase
OGH68_RS23135	COG1396	sequence-specific DNA binding
OGH68_RS23140	COG0740	serine-type endopeptidase activity
OGH68_RS23145	COG0740	serine-type endopeptidase activity
OGH68_RS23155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OGH68_RS23165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OGH68_RS23190	COG1595	DNA-templated transcription, initiation
OGH68_RS23200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OGH68_RS23240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OGH68_RS23250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OGH68_RS23270	COG1331	Highly conserved protein containing a thioredoxin domain
OGH68_RS23285	COG0463	Glycosyl transferase, family 2
OGH68_RS23305	COG1309	transcriptional regulator
OGH68_RS23310	COG0477	Major facilitator Superfamily
OGH68_RS23320	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OGH68_RS23390	COG1278	Cold shock
OGH68_RS23405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
OGH68_RS23420	COG1414	Transcriptional regulator
OGH68_RS23425	COG0251	oxidation-reduction process
OGH68_RS23430	COG2610	gluconate transmembrane transporter activity
OGH68_RS23470	COG0489	protein tyrosine kinase activity
OGH68_RS23515	COG2885	chlorophyll binding
OGH68_RS23540	COG0667	Aldo Keto reductase
OGH68_RS23545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OGH68_RS23550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OGH68_RS23570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGH68_RS23575	COG0450	alkyl hydroperoxide reductase
OGH68_RS23635	COG0114	fumarate hydratase activity
OGH68_RS23660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OGH68_RS23660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OGH68_RS23685	COG0778	Nitroreductase
OGH68_RS23690	COG1722	exodeoxyribonuclease VII activity
OGH68_RS23695	COG1570	exodeoxyribonuclease VII activity
OGH68_RS23700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OGH68_RS23715	COG0012	GTP binding
OGH68_RS23750	COG1132	(ABC) transporter
OGH68_RS23760	COG1132	(ABC) transporter
OGH68_RS23825	COG1842	Phage shock protein A
OGH68_RS23845	COG1053	succinate dehydrogenase
OGH68_RS23865	COG1217	gtp-binding protein TYPA
OGH68_RS23870	COG4166	transmembrane transport
OGH68_RS23875	COG0601	transmembrane transport
OGH68_RS23880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS23885	COG0444	Belongs to the ABC transporter superfamily
OGH68_RS23890	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS23910	COG0601	transmembrane transport
OGH68_RS23915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS23925	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS23945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OGH68_RS23995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGH68_RS24000	COG1611	Belongs to the LOG family
OGH68_RS24005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OGH68_RS24015	COG2818	Glycosylase
OGH68_RS24020	COG1024	Enoyl-CoA hydratase
OGH68_RS24035	COG1595	DNA-templated transcription, initiation
OGH68_RS24045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OGH68_RS24050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OGH68_RS24085	COG0598	Magnesium transport protein CorA
OGH68_RS24105	COG2095	MarC family integral membrane protein
OGH68_RS24115	COG1432	Conserved Protein
OGH68_RS24125	COG0513	Belongs to the DEAD box helicase family
OGH68_RS24220	COG3547	Transposase (IS116 IS110 IS902 family)
OGH68_RS24275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OGH68_RS24330	COG3480	Lon protease (S16) C-terminal proteolytic domain
OGH68_RS24340	COG1615	UPF0182 protein
OGH68_RS24375	COG0483	inositol monophosphate 1-phosphatase activity
OGH68_RS24385	COG2076	Multidrug Resistance protein
OGH68_RS24395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OGH68_RS24405	COG2135	peptidase activity
OGH68_RS24415	COG1595	DNA-templated transcription, initiation
OGH68_RS24420	COG5662	AntiSigma factor
OGH68_RS24425	COG2199	diguanylate cyclase activity
OGH68_RS24425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OGH68_RS24440	COG0242	peptide deformylase activity
OGH68_RS24450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OGH68_RS24475	COG2188	Transcriptional regulator
OGH68_RS24485	COG1175	transmembrane transport
OGH68_RS24490	COG0395	ABC-type sugar transport system, permease component
OGH68_RS24495	COG1472	Belongs to the glycosyl hydrolase 3 family
OGH68_RS24515	COG1597	lipid kinase activity
OGH68_RS24545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OGH68_RS24550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OGH68_RS24555	COG0142	geranyltranstransferase activity
OGH68_RS24575	COG5640	endopeptidase activity
OGH68_RS24605	COG4106	trans-aconitate 2-methyltransferase activity
OGH68_RS24610	COG1126	abc transporter atp-binding protein
OGH68_RS24615	COG0765	amino acid transport
OGH68_RS24635	COG3540	Alkaline phosphatase
OGH68_RS24640	COG0604	alcohol dehydrogenase
OGH68_RS24680	COG0508	dehydrogenase complex catalyzes the overall conversion of
OGH68_RS24680	COG0567	Dehydrogenase, E1 component
OGH68_RS24685	COG2205	protein histidine kinase activity
OGH68_RS24690	COG0745	RESPONSE REGULATOR receiver
OGH68_RS24710	COG1131	(ABC) transporter
OGH68_RS24720	COG1595	DNA-templated transcription, initiation
OGH68_RS24735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OGH68_RS24740	COG1357	PFAM Pentapeptide repeats (8 copies)
OGH68_RS24825	COG0768	penicillin binding
OGH68_RS24860	COG1793	dna ligase
OGH68_RS24860	COG3285	dna ligase
OGH68_RS24865	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OGH68_RS24875	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS24970	COG0018	arginyl-trna synthetase
OGH68_RS24975	COG0019	diaminopimelate decarboxylase activity
OGH68_RS24980	COG0460	homoserine dehydrogenase
OGH68_RS24985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OGH68_RS24990	COG0083	homoserine kinase activity
OGH68_RS25000	COG1316	TRANSCRIPTIONal
OGH68_RS25005	COG0254	rRNA binding
OGH68_RS25010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OGH68_RS25015	COG2890	protein-(glutamine-N5) methyltransferase activity
OGH68_RS25025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OGH68_RS25030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OGH68_RS25055	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OGH68_RS25060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OGH68_RS25065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OGH68_RS25070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OGH68_RS25075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OGH68_RS25080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OGH68_RS25085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OGH68_RS25100	COG2197	response regulator
OGH68_RS25105	COG4585	Histidine kinase
OGH68_RS25120	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS25135	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OGH68_RS25160	COG1131	(ABC) transporter
OGH68_RS25190	COG0183	Belongs to the thiolase family
OGH68_RS25210	COG2205	protein histidine kinase activity
OGH68_RS25245	COG3548	integral membrane protein
OGH68_RS25270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS25270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS25310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OGH68_RS25315	COG0857	belongs to the CobB CobQ family
OGH68_RS25315	COG0280	phosphate acetyltransferase
OGH68_RS25320	COG0205	6-phosphofructokinase activity
OGH68_RS25345	COG4565	transcriptional regulatory protein
OGH68_RS25350	COG3290	protein histidine kinase activity
OGH68_RS25355	COG1301	dicarboxylic acid transport
OGH68_RS25365	COG0667	Aldo Keto reductase
OGH68_RS25375	COG1522	sequence-specific DNA binding
OGH68_RS25395	COG3973	AAA domain
OGH68_RS25400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OGH68_RS25415	COG0366	Alpha amylase catalytic
OGH68_RS25420	COG0058	SHG alpha-glucan phosphorylase activity
OGH68_RS25460	COG4974	Belongs to the 'phage' integrase family
OGH68_RS25510	COG1674	ftsk spoiiie
OGH68_RS25580	COG2252	PERMEase
OGH68_RS25610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS25640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OGH68_RS25660	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS25695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS25700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OGH68_RS25720	COG0489	protein tyrosine kinase activity
OGH68_RS25730	COG1132	(ABC) transporter
OGH68_RS25735	COG1132	(ABC) transporter
OGH68_RS25750	COG1376	ErfK ybiS ycfS ynhG family protein
OGH68_RS25810	COG1760	l-serine dehydratase
OGH68_RS25815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OGH68_RS25820	COG0509	glycine decarboxylation via glycine cleavage system
OGH68_RS25825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OGH68_RS25845	COG0747	negative chemotaxis
OGH68_RS25850	COG0601	transmembrane transport
OGH68_RS25855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS25860	COG0444	Belongs to the ABC transporter superfamily
OGH68_RS25865	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS25870	COG2860	membrane
OGH68_RS25885	COG2378	regulation of single-species biofilm formation
OGH68_RS25915	COG0482	sulfurtransferase activity
OGH68_RS25935	COG4221	oxidoreductase activity
OGH68_RS25945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OGH68_RS25955	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OGH68_RS25960	COG0154	amidase activity
OGH68_RS25970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OGH68_RS25990	COG2409	Drug exporters of the RND superfamily
OGH68_RS25995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OGH68_RS26020	COG2197	response regulator
OGH68_RS26030	COG2133	pyrroloquinoline quinone binding
OGH68_RS26035	COG0667	Aldo Keto reductase
OGH68_RS26045	COG3300	MHYT domain
OGH68_RS26045	COG5001	Diguanylate cyclase
OGH68_RS26055	COG0440	acetolactate synthase activity
OGH68_RS26060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OGH68_RS26090	COG0506	proline dehydrogenase activity
OGH68_RS26095	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS26110	COG1695	Transcriptional regulator
OGH68_RS26120	COG0473	3-isopropylmalate dehydrogenase activity
OGH68_RS26125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OGH68_RS26135	COG0832	Belongs to the urease beta subunit family
OGH68_RS26135	COG0831	urea catabolic process
OGH68_RS26140	COG0804	urea catabolic process
OGH68_RS26145	COG2957	Belongs to the agmatine deiminase family
OGH68_RS26150	COG1309	transcriptional regulator
OGH68_RS26155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OGH68_RS26165	COG1609	Transcriptional regulator
OGH68_RS26170	COG1472	Belongs to the glycosyl hydrolase 3 family
OGH68_RS26185	COG2353	YceI-like domain
OGH68_RS26195	COG0366	Alpha amylase catalytic
OGH68_RS26195	COG1470	cell adhesion involved in biofilm formation
OGH68_RS26200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS26220	COG2018	Roadblock/LC7 domain
OGH68_RS26240	COG2018	Roadblock/LC7 domain
OGH68_RS26245	COG5002	protein histidine kinase activity
OGH68_RS26255	COG0179	Fumarylacetoacetate (FAA) hydrolase
OGH68_RS26260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OGH68_RS26315	COG1414	Transcriptional regulator
OGH68_RS26320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OGH68_RS26325	COG0066	3-isopropylmalate dehydratase activity
OGH68_RS26335	COG0776	regulation of translation
OGH68_RS26345	COG1920	GTP binding
OGH68_RS26355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OGH68_RS26360	COG1181	Belongs to the D-alanine--D-alanine ligase family
OGH68_RS26380	COG0351	phosphomethylpyrimidine kinase
OGH68_RS26385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OGH68_RS26390	COG1461	Dihydroxyacetone kinase
OGH68_RS26400	COG0326	Molecular chaperone. Has ATPase activity
OGH68_RS26410	COG0742	ribosomal rna small subunit methyltransferase
OGH68_RS26415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OGH68_RS26430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OGH68_RS26435	COG0571	ribonuclease III activity
OGH68_RS26445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OGH68_RS26450	COG2340	Cysteine-rich secretory protein family
OGH68_RS26455	COG1254	Belongs to the acylphosphatase family
OGH68_RS26465	COG1196	nuclear chromosome segregation
OGH68_RS26470	COG0477	Major facilitator Superfamily
OGH68_RS26480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OGH68_RS26510	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OGH68_RS26525	COG0442	prolyl-tRNA aminoacylation
OGH68_RS26535	COG0228	four-way junction DNA binding
OGH68_RS26540	COG1837	Belongs to the UPF0109 family
OGH68_RS26545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OGH68_RS26550	COG0336	Belongs to the RNA methyltransferase TrmD family
OGH68_RS26555	COG0335	large ribosomal subunit rRNA binding
OGH68_RS26560	COG0681	Belongs to the peptidase S26 family
OGH68_RS26575	COG0681	Belongs to the peptidase S26 family
OGH68_RS26590	COG0792	nuclease activity
OGH68_RS26605	COG1191	sigma factor activity
OGH68_RS26620	COG0052	Belongs to the universal ribosomal protein uS2 family
OGH68_RS26625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OGH68_RS26630	COG0528	UMP kinase activity
OGH68_RS26635	COG0233	cytoplasmic translational termination
OGH68_RS26640	COG0575	Belongs to the CDS family
OGH68_RS26660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OGH68_RS26675	COG3842	ATPase activity
OGH68_RS26690	COG1136	(ABC) transporter
OGH68_RS26695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OGH68_RS26705	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS26735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OGH68_RS26750	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS26755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OGH68_RS26760	COG3842	ATPase activity
OGH68_RS26765	COG1176	ABC-type spermidine putrescine transport system, permease component I
OGH68_RS26770	COG1177	transmembrane transport
OGH68_RS26775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS26805	COG2508	Transcriptional regulator
OGH68_RS26815	COG0697	spore germination
OGH68_RS26845	COG2208	phosphoserine phosphatase activity
OGH68_RS26845	COG2770	Histidine kinase
OGH68_RS26910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OGH68_RS26915	COG0750	zinc metalloprotease
OGH68_RS26920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OGH68_RS26935	COG0442	prolyl-tRNA aminoacylation
OGH68_RS26955	COG0779	Required for maturation of 30S ribosomal subunits
OGH68_RS26970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OGH68_RS26980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OGH68_RS26985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OGH68_RS27000	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS27010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS27015	COG0601	transmembrane transport
OGH68_RS27020	COG4166	transmembrane transport
OGH68_RS27025	COG0455	bacterial-type flagellum organization
OGH68_RS27045	COG3266	domain, Protein
OGH68_RS27050	COG1404	Belongs to the peptidase S8 family
OGH68_RS27110	COG1674	ftsk spoiiie
OGH68_RS27120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OGH68_RS27125	COG1185	polyribonucleotide nucleotidyltransferase activity
OGH68_RS27130	COG0612	Peptidase, M16
OGH68_RS27135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OGH68_RS27155	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OGH68_RS27160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OGH68_RS27165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OGH68_RS27190	COG2208	phosphoserine phosphatase activity
OGH68_RS27190	COG2770	Histidine kinase
OGH68_RS27195	COG3437	response regulator, receiver
OGH68_RS27195	COG3850	Histidine kinase
OGH68_RS27195	COG2205	protein histidine kinase activity
OGH68_RS27195	COG4999	Histidine kinase
OGH68_RS27205	COG1674	ftsk spoiiie
OGH68_RS27215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OGH68_RS27225	COG1546	Belongs to the CinA family
OGH68_RS27225	COG1058	Belongs to the CinA family
OGH68_RS27230	COG1396	sequence-specific DNA binding
OGH68_RS27235	COG0783	Belongs to the Dps family
OGH68_RS27245	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS27250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OGH68_RS27255	COG1201	RNA secondary structure unwinding
OGH68_RS27300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OGH68_RS27310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OGH68_RS27315	COG0765	amino acid transport
OGH68_RS27320	COG0765	amino acid transport
OGH68_RS27325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS27330	COG1126	abc transporter atp-binding protein
OGH68_RS27340	COG2205	protein histidine kinase activity
OGH68_RS27350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OGH68_RS27370	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS27370	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS27370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS27370	COG0300	oxidoreductase activity
OGH68_RS27370	COG3321	synthase
OGH68_RS27390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OGH68_RS27405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGH68_RS27415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OGH68_RS27455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGH68_RS27460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OGH68_RS27465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OGH68_RS27470	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS27495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS27525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OGH68_RS27535	COG2409	Drug exporters of the RND superfamily
OGH68_RS27545	COG0142	geranyltranstransferase activity
OGH68_RS27550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS27560	COG3903	Transcriptional regulator
OGH68_RS27560	COG3629	intracellular signal transduction
OGH68_RS27570	COG3629	intracellular signal transduction
OGH68_RS27570	COG3903	Transcriptional regulator
OGH68_RS27585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OGH68_RS27605	COG1733	regulation of RNA biosynthetic process
OGH68_RS27610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OGH68_RS27630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OGH68_RS27640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OGH68_RS27645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OGH68_RS27655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OGH68_RS27695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OGH68_RS27700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OGH68_RS27705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OGH68_RS27735	COG0588	phosphoglycerate mutase activity
OGH68_RS27755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OGH68_RS27790	COG2186	Transcriptional regulator
OGH68_RS27795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OGH68_RS27810	COG0187	DNA topoisomerase II activity
OGH68_RS27815	COG4585	Histidine kinase
OGH68_RS27820	COG2197	response regulator
OGH68_RS27830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS27840	COG3290	protein histidine kinase activity
OGH68_RS27860	COG0366	Alpha amylase catalytic
OGH68_RS27875	COG0024	Methionine aminopeptidase
OGH68_RS27890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OGH68_RS27895	COG0612	Peptidase, M16
OGH68_RS27910	COG1802	Transcriptional regulator
OGH68_RS27915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OGH68_RS27935	COG1435	thymidine kinase activity
OGH68_RS27965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OGH68_RS27980	COG0745	RESPONSE REGULATOR receiver
OGH68_RS27985	COG2205	protein histidine kinase activity
OGH68_RS28010	COG0756	dUTP diphosphatase activity
OGH68_RS28020	COG1136	(ABC) transporter
OGH68_RS28020	COG4591	ABC-type transport system involved in lipoprotein release permease component
OGH68_RS28050	COG0569	domain protein
OGH68_RS28055	COG0531	amino acid
OGH68_RS28060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OGH68_RS28065	COG1309	transcriptional regulator
OGH68_RS28090	COG4335	DNA alkylation repair
OGH68_RS28110	COG1309	transcriptional regulator
OGH68_RS28145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGH68_RS28155	COG3629	intracellular signal transduction
OGH68_RS28185	COG2814	Major facilitator Superfamily
OGH68_RS28195	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OGH68_RS28200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OGH68_RS28205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OGH68_RS28210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGH68_RS28215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OGH68_RS28240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS28250	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS28285	COG0477	Major facilitator Superfamily
OGH68_RS28320	COG1309	transcriptional regulator
OGH68_RS28345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OGH68_RS28360	COG2890	protein-(glutamine-N5) methyltransferase activity
OGH68_RS28365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OGH68_RS28385	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
OGH68_RS28420	COG3209	COG3209 Rhs family protein
OGH68_RS28420	COG4104	PAAR repeat-containing protein
OGH68_RS28430	COG1609	Transcriptional regulator
OGH68_RS28435	COG1653	transport
OGH68_RS28440	COG1175	transmembrane transport
OGH68_RS28445	COG0395	ABC-type sugar transport system, permease component
OGH68_RS28465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OGH68_RS28475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OGH68_RS28480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OGH68_RS28510	COG1335	isochorismatase
OGH68_RS28595	COG2226	methyltransferase
OGH68_RS28610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGH68_RS28615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OGH68_RS28650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OGH68_RS28660	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS28665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS28670	COG2192	nodulation
OGH68_RS28685	COG0859	PFAM glycosyl transferase family 9
OGH68_RS28695	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS28700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OGH68_RS28705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OGH68_RS28705	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OGH68_RS28710	COG0859	PFAM glycosyl transferase family 9
OGH68_RS28720	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS28725	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS28735	COG2273	Hydrolase Family 16
OGH68_RS28735	COG5297	Belongs to the glycosyl hydrolase family 6
OGH68_RS28765	COG0395	ABC-type sugar transport system, permease component
OGH68_RS28770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS28775	COG1609	Transcriptional regulator
OGH68_RS28780	COG2182	Extracellular solute-binding protein
OGH68_RS28785	COG1175	transmembrane transport
OGH68_RS28795	COG0366	Alpha amylase catalytic
OGH68_RS28815	COG1799	cell septum assembly
OGH68_RS28835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS28840	COG2040	homocysteine
OGH68_RS28850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OGH68_RS28870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OGH68_RS28880	COG1024	Enoyl-CoA hydratase
OGH68_RS28940	COG0642	Histidine kinase
OGH68_RS28980	COG2197	response regulator
OGH68_RS28985	COG4585	Histidine kinase
OGH68_RS28995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OGH68_RS29020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OGH68_RS29040	COG1653	transport
OGH68_RS29045	COG1175	transmembrane transport
OGH68_RS29050	COG0395	ABC-type sugar transport system, permease component
OGH68_RS29060	COG4213	ABC transporter substrate-binding protein
OGH68_RS29070	COG4214	carbohydrate transport
OGH68_RS29075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OGH68_RS29080	COG0531	amino acid
OGH68_RS29090	COG1316	TRANSCRIPTIONal
OGH68_RS29105	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS29115	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS29135	COG1024	Enoyl-CoA hydratase
OGH68_RS29135	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS29140	COG0183	Belongs to the thiolase family
OGH68_RS29145	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OGH68_RS29160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OGH68_RS29170	COG0446	pyridine nucleotide-disulphide oxidoreductase
OGH68_RS29180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OGH68_RS29185	COG3253	May function as heme-dependent peroxidase
OGH68_RS29195	COG3220	belongs to the UPF0276 family
OGH68_RS29290	COG1136	(ABC) transporter
OGH68_RS29300	COG1653	transport
OGH68_RS29305	COG0366	Alpha amylase catalytic
OGH68_RS29315	COG1175	transmembrane transport
OGH68_RS29320	COG0395	ABC-type sugar transport system, permease component
OGH68_RS29325	COG1846	Transcriptional regulator
OGH68_RS29330	COG1764	response to oxidative stress
OGH68_RS29365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OGH68_RS29370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OGH68_RS29380	COG2197	response regulator
OGH68_RS29385	COG4585	Histidine kinase
OGH68_RS29390	COG1131	(ABC) transporter
OGH68_RS29405	COG1051	belongs to the nudix hydrolase family
OGH68_RS29410	COG1073	alpha beta
OGH68_RS29460	COG2706	6-phosphogluconolactonase activity
OGH68_RS29475	COG0346	lactoylglutathione lyase activity
OGH68_RS29510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OGH68_RS29515	COG0583	DNA-binding transcription factor activity
OGH68_RS29585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OGH68_RS29595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OGH68_RS29600	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OGH68_RS29620	COG0529	Catalyzes the synthesis of activated sulfate
OGH68_RS29625	COG0175	sulfate reduction
OGH68_RS29635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS29650	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS29670	COG0745	RESPONSE REGULATOR receiver
OGH68_RS29675	COG5002	protein histidine kinase activity
OGH68_RS29700	COG0475	glutathione-regulated potassium exporter activity
OGH68_RS29720	COG1796	DNA polymerase
OGH68_RS29720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OGH68_RS29725	COG1162	GTPase activity
OGH68_RS29740	COG1404	Belongs to the peptidase S8 family
OGH68_RS29750	COG0028	Belongs to the TPP enzyme family
OGH68_RS29770	COG1802	Transcriptional regulator
OGH68_RS29820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS29825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS29865	COG1132	(ABC) transporter
OGH68_RS29870	COG3835	regulator
OGH68_RS29885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OGH68_RS29890	COG2252	PERMEase
OGH68_RS29930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OGH68_RS29955	COG2326	polyphosphate kinase activity
OGH68_RS29965	COG2197	response regulator
OGH68_RS29975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OGH68_RS29980	COG0318	PFAM AMP-dependent synthetase and ligase
OGH68_RS29995	COG3960	tartronate-semialdehyde synthase activity
OGH68_RS30010	COG0753	catalase activity
OGH68_RS30015	COG2084	Dehydrogenase
OGH68_RS30020	COG3622	Belongs to the hyi family
OGH68_RS30040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OGH68_RS30070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OGH68_RS30075	COG1127	ABC transporter
OGH68_RS30110	COG2351	hydroxyisourate hydrolase activity
OGH68_RS30130	COG2233	PERMEase
OGH68_RS30160	COG2249	NAD(P)H dehydrogenase (quinone) activity
OGH68_RS30165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OGH68_RS30170	COG2272	Belongs to the type-B carboxylesterase lipase family
OGH68_RS30175	COG0384	phenazine biosynthesis protein PhzF
OGH68_RS30180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGH68_RS30190	COG0745	RESPONSE REGULATOR receiver
OGH68_RS30195	COG2205	protein histidine kinase activity
OGH68_RS30200	COG2340	Cysteine-rich secretory protein family
OGH68_RS30220	COG0702	epimerase
OGH68_RS30225	COG1595	DNA-templated transcription, initiation
OGH68_RS30230	COG0154	amidase activity
OGH68_RS30260	COG0754	glutathionylspermidine amidase activity
OGH68_RS30335	COG0714	Associated with various cellular activities
OGH68_RS30355	COG0006	proline dipeptidase activity
OGH68_RS30370	COG0477	Major facilitator Superfamily
OGH68_RS30440	COG0515	serine threonine protein kinase
OGH68_RS30440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OGH68_RS30450	COG0768	penicillin binding
OGH68_RS30490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGH68_RS30490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGH68_RS30540	COG3629	intracellular signal transduction
OGH68_RS30540	COG3903	Transcriptional regulator
OGH68_RS30560	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OGH68_RS30600	COG2197	response regulator
OGH68_RS30605	COG4585	Histidine kinase
OGH68_RS30615	COG0577	efflux transmembrane transporter activity
OGH68_RS30615	COG1136	(ABC) transporter
OGH68_RS30620	COG3537	Alpha-1,2-mannosidase
OGH68_RS30625	COG1414	Transcriptional regulator
OGH68_RS30630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OGH68_RS30635	COG4266	Belongs to the allantoicase family
OGH68_RS30640	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS30665	COG0673	inositol 2-dehydrogenase activity
OGH68_RS30670	COG2188	Transcriptional regulator
OGH68_RS30695	COG1940	carbohydrate kinase activity
OGH68_RS30710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGH68_RS30730	COG1126	abc transporter atp-binding protein
OGH68_RS30745	COG2124	cytochrome p450
OGH68_RS30755	COG0405	Gamma-glutamyltransferase
OGH68_RS30780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS30785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OGH68_RS30795	COG1953	Uracil, thiamine, allantoin
OGH68_RS30805	COG3486	L-lysine 6-monooxygenase (NADPH) activity
OGH68_RS30810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OGH68_RS30830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS30835	COG1120	ATPase activity
OGH68_RS30840	COG1132	(ABC) transporter
OGH68_RS30845	COG1132	(ABC) transporter
OGH68_RS30850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS30855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGH68_RS30860	COG1120	ATPase activity
OGH68_RS30880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS30885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OGH68_RS30890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OGH68_RS30895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OGH68_RS30960	COG1309	transcriptional regulator
OGH68_RS30970	COG2986	histidine ammonia-lyase
OGH68_RS30985	COG0405	Gamma-glutamyltransferase
OGH68_RS30990	COG0483	inositol monophosphate 1-phosphatase activity
OGH68_RS31020	COG0395	ABC-type sugar transport system, permease component
OGH68_RS31060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OGH68_RS31065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OGH68_RS31075	COG1929	Belongs to the glycerate kinase type-1 family
OGH68_RS31090	COG0559	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS31120	COG0688	phosphatidylethanolamine metabolic process
OGH68_RS31125	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS31140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS31140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS31145	COG0604	alcohol dehydrogenase
OGH68_RS31155	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS31185	COG2172	sigma factor antagonist activity
OGH68_RS31185	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS31185	COG2208	phosphoserine phosphatase activity
OGH68_RS31205	COG1834	amidinotransferase
OGH68_RS31210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGH68_RS31215	COG2362	D-Aminopeptidase
OGH68_RS31220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGH68_RS31225	COG0823	Involved in the tonB-independent uptake of proteins
OGH68_RS31225	COG4946	Tricorn protease homolog
OGH68_RS31225	COG1506	peptidase
OGH68_RS31230	COG1619	proteins homologs of microcin C7 resistance protein MccF
OGH68_RS31240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OGH68_RS31295	COG0531	amino acid
OGH68_RS31300	COG1064	alcohol dehydrogenase
OGH68_RS31325	COG1793	dna ligase
OGH68_RS31340	COG2154	pterin-4-alpha-carbinolamine dehydratase
OGH68_RS31350	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS31365	COG3387	PFAM Glycoside hydrolase 15-related
OGH68_RS31385	COG0656	L-ascorbic acid biosynthetic process
OGH68_RS31405	COG1131	(ABC) transporter
OGH68_RS31410	COG4585	Histidine kinase
OGH68_RS31455	COG1309	transcriptional regulator
OGH68_RS31465	COG0137	argininosuccinate synthase activity
OGH68_RS31470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OGH68_RS31480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OGH68_RS31485	COG3383	formate dehydrogenase (NAD+) activity
OGH68_RS31490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OGH68_RS31495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OGH68_RS31540	COG1940	carbohydrate kinase activity
OGH68_RS31545	COG1129	ABC transporter
OGH68_RS31550	COG1172	Belongs to the binding-protein-dependent transport system permease family
OGH68_RS31560	COG0673	inositol 2-dehydrogenase activity
OGH68_RS31580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OGH68_RS31630	COG2223	nitrite transmembrane transporter activity
OGH68_RS31640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OGH68_RS31650	COG0045	succinate-CoA ligase (ADP-forming) activity
OGH68_RS31660	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS31715	COG1129	ABC transporter
OGH68_RS31725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS31730	COG1869	D-ribose catabolic process
OGH68_RS31745	COG0477	Major facilitator Superfamily
OGH68_RS31785	COG3401	FG-GAP repeat protein
OGH68_RS31895	COG0515	serine threonine protein kinase
OGH68_RS31895	COG2815	serine threonine protein kinase
OGH68_RS31905	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OGH68_RS31960	COG0483	inositol monophosphate 1-phosphatase activity
OGH68_RS31970	COG1105	Belongs to the carbohydrate kinase PfkB family
OGH68_RS32015	COG1401	restriction endodeoxyribonuclease activity
OGH68_RS32025	COG0210	DNA helicase
OGH68_RS32105	COG0789	Transcriptional regulator
OGH68_RS32125	COG2855	membrane
OGH68_RS32145	COG1070	Carbohydrate kinase
OGH68_RS32240	COG1554	hydrolase, family 65, central catalytic
OGH68_RS32250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OGH68_RS32255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OGH68_RS32260	COG0589	response to stress
OGH68_RS32310	COG1486	melibiose metabolic process
OGH68_RS32315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OGH68_RS32315	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
OGH68_RS32320	COG3012	SEC-C Motif Domain Protein
OGH68_RS32360	COG1793	dna ligase
OGH68_RS32385	COG0463	Glycosyl transferase, family 2
OGH68_RS32390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OGH68_RS32430	COG2208	phosphoserine phosphatase activity
OGH68_RS32440	COG2172	sigma factor antagonist activity
OGH68_RS32445	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS32450	COG1366	Belongs to the anti-sigma-factor antagonist family
OGH68_RS32475	COG0488	(ABC) transporter
OGH68_RS32490	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OGH68_RS32555	COG1515	deoxyribonuclease V activity
OGH68_RS32565	COG3268	Saccharopine dehydrogenase
OGH68_RS32570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OGH68_RS32575	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS32580	COG0183	Belongs to the thiolase family
OGH68_RS32585	COG1250	3-hydroxyacyl-CoA dehydrogenase
OGH68_RS32585	COG1024	Enoyl-CoA hydratase
OGH68_RS32595	COG0789	Transcriptional regulator
OGH68_RS32670	COG0395	ABC-type sugar transport system, permease component
OGH68_RS32695	COG3226	Transcriptional regulator
OGH68_RS32700	COG0110	maltose O-acetyltransferase activity
OGH68_RS32715	COG2936	dipeptidyl-peptidase activity
OGH68_RS32725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OGH68_RS32740	COG0488	(ABC) transporter
OGH68_RS32745	COG2183	response to ionizing radiation
OGH68_RS32760	COG4977	sequence-specific DNA binding
OGH68_RS32770	COG1024	Enoyl-CoA hydratase
OGH68_RS32780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OGH68_RS32810	COG0371	Dehydrogenase
OGH68_RS32830	COG1388	LysM domain
OGH68_RS32830	COG1134	teichoic acid transport
OGH68_RS32835	COG1562	ergosterol biosynthetic process
OGH68_RS32845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OGH68_RS32855	COG1657	PFAM Prenyltransferase squalene oxidase
OGH68_RS32885	COG2365	Tyrosine phosphatase family
OGH68_RS32945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGH68_RS32955	COG1609	Transcriptional regulator
OGH68_RS32960	COG4209	transmembrane transport
OGH68_RS32965	COG0395	ABC-type sugar transport system, permease component
OGH68_RS33020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OGH68_RS33030	COG1116	anion transmembrane transporter activity
OGH68_RS33040	COG0531	amino acid
OGH68_RS33065	COG3958	Transketolase
OGH68_RS33070	COG3959	Transketolase, thiamine diphosphate binding domain
OGH68_RS33090	COG0395	ABC-type sugar transport system, permease component
OGH68_RS33125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS33140	COG5297	Belongs to the glycosyl hydrolase family 6
OGH68_RS33140	COG4733	cellulase activity
OGH68_RS33145	COG5297	Belongs to the glycosyl hydrolase family 6
OGH68_RS33180	COG4677	pectinesterase activity
OGH68_RS33185	COG3866	Pectate lyase
OGH68_RS33190	COG2755	lipolytic protein G-D-S-L family
OGH68_RS33195	COG1653	transport
OGH68_RS33215	COG0395	ABC-type sugar transport system, permease component
OGH68_RS33220	COG1175	transmembrane transport
OGH68_RS33235	COG1802	Transcriptional regulator
OGH68_RS33250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OGH68_RS33280	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS33285	COG0302	gtp cyclohydrolase
OGH68_RS33295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS33305	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OGH68_RS33310	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS33335	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS33375	COG2226	methyltransferase
OGH68_RS33380	COG0501	Belongs to the peptidase M48B family
OGH68_RS33405	COG2226	methyltransferase
OGH68_RS33415	COG2197	response regulator
OGH68_RS33420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OGH68_RS33435	COG1796	DNA polymerase
OGH68_RS33435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OGH68_RS33455	COG1051	belongs to the nudix hydrolase family
OGH68_RS33460	COG1132	(ABC) transporter
OGH68_RS33465	COG2124	cytochrome p450
OGH68_RS33490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OGH68_RS33505	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OGH68_RS33510	COG1349	DNA-binding transcription factor activity
OGH68_RS33530	COG1063	alcohol dehydrogenase
OGH68_RS33570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGH68_RS33635	COG3618	amidohydrolase
OGH68_RS33640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OGH68_RS33665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGH68_RS33670	COG3275	phosphorelay sensor kinase activity
OGH68_RS33720	COG2267	carboxylic ester hydrolase activity
OGH68_RS33740	COG0583	DNA-binding transcription factor activity
OGH68_RS33750	COG1053	succinate dehydrogenase
OGH68_RS33755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OGH68_RS33770	COG0583	DNA-binding transcription factor activity
OGH68_RS33790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OGH68_RS33805	COG2182	Extracellular solute-binding protein
OGH68_RS33820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OGH68_RS33825	COG0121	glutamine amidotransferase
OGH68_RS33830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OGH68_RS33855	COG1414	Transcriptional regulator
OGH68_RS33860	COG0183	Belongs to the thiolase family
OGH68_RS33865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OGH68_RS33875	COG0679	Auxin Efflux Carrier
OGH68_RS33930	COG2814	Major facilitator Superfamily
OGH68_RS33945	COG1012	belongs to the aldehyde dehydrogenase family
OGH68_RS33950	COG2130	NADP-dependent
OGH68_RS33995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OGH68_RS34050	COG1278	Cold shock
OGH68_RS34075	COG3397	chitin binding
OGH68_RS34085	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS34095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS34125	COG1063	alcohol dehydrogenase
OGH68_RS34130	COG3265	gluconokinase activity
OGH68_RS34150	COG2197	response regulator
OGH68_RS34155	COG4585	Histidine kinase
OGH68_RS34210	COG3540	Alkaline phosphatase
OGH68_RS34230	COG1309	transcriptional regulator
OGH68_RS34245	COG2233	PERMEase
OGH68_RS34250	COG0402	S-adenosylhomocysteine deaminase activity
OGH68_RS34265	COG0673	inositol 2-dehydrogenase activity
OGH68_RS34275	COG1349	DNA-binding transcription factor activity
OGH68_RS34290	COG0395	ABC-type sugar transport system, permease component
OGH68_RS34295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OGH68_RS34315	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS34320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OGH68_RS34340	COG1609	Transcriptional regulator
OGH68_RS34345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OGH68_RS34380	COG4989	oxidoreductase activity
OGH68_RS34410	COG3458	cephalosporin-C deacetylase activity
OGH68_RS34460	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS34465	COG1960	acyl-CoA dehydrogenase activity
OGH68_RS34475	COG0601	transmembrane transport
OGH68_RS34480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS34485	COG0444	Belongs to the ABC transporter superfamily
OGH68_RS34510	COG2203	Gaf domain
OGH68_RS34510	COG2199	diguanylate cyclase activity
OGH68_RS34520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OGH68_RS34525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OGH68_RS34535	COG2018	Roadblock/LC7 domain
OGH68_RS34560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OGH68_RS34565	COG3239	Fatty acid desaturase
OGH68_RS34595	COG2018	Roadblock/LC7 domain
OGH68_RS34605	COG1063	alcohol dehydrogenase
OGH68_RS34610	COG0156	8-amino-7-oxononanoate synthase activity
OGH68_RS34615	COG0583	DNA-binding transcription factor activity
OGH68_RS34640	COG2814	Major facilitator Superfamily
OGH68_RS34645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGH68_RS34645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGH68_RS34655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGH68_RS34660	COG0765	amino acid transport
OGH68_RS34700	COG0463	Glycosyl transferase, family 2
OGH68_RS34715	COG1653	transport
OGH68_RS34720	COG4209	transmembrane transport
OGH68_RS34725	COG0395	ABC-type sugar transport system, permease component
OGH68_RS34790	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OGH68_RS34820	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS34835	COG2207	Transcriptional regulator
OGH68_RS34840	COG0346	lactoylglutathione lyase activity
OGH68_RS34855	COG1597	lipid kinase activity
OGH68_RS34860	COG0277	FAD linked oxidase domain protein
OGH68_RS34895	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OGH68_RS34910	COG1595	DNA-templated transcription, initiation
OGH68_RS34990	COG0330	HflC and HflK could
OGH68_RS34995	COG0443	Heat shock 70 kDa protein
OGH68_RS35000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OGH68_RS35025	COG0662	Cupin 2, conserved barrel domain protein
OGH68_RS35045	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OGH68_RS35060	COG4608	Belongs to the ABC transporter superfamily
OGH68_RS35065	COG0444	Belongs to the ABC transporter superfamily
OGH68_RS35080	COG0601	transmembrane transport
OGH68_RS35085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGH68_RS35115	COG3938	Belongs to the proline racemase family
OGH68_RS35165	COG1278	Cold shock
OGH68_RS35185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OGH68_RS35220	COG0523	cobalamin synthesis protein
OGH68_RS35245	COG2226	methyltransferase
OGH68_RS35265	COG1082	Xylose isomerase domain protein TIM barrel
OGH68_RS35270	COG0673	inositol 2-dehydrogenase activity
OGH68_RS35275	COG2814	Major facilitator Superfamily
OGH68_RS35290	COG3962	Belongs to the TPP enzyme family
OGH68_RS35295	COG3718	enzyme involved in inositol metabolism
OGH68_RS35305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGH68_RS35310	COG1609	Transcriptional regulator
OGH68_RS35350	COG0366	Alpha amylase catalytic
OGH68_RS35385	COG0702	epimerase
OGH68_RS35415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS35440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OGH68_RS35445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS35450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS35450	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGH68_RS35465	COG3321	synthase
OGH68_RS35465	COG0604	alcohol dehydrogenase
OGH68_RS35470	COG0604	alcohol dehydrogenase
OGH68_RS35470	COG3321	synthase
OGH68_RS35475	COG0604	alcohol dehydrogenase
OGH68_RS35475	COG3321	synthase
OGH68_RS35480	COG0477	Major facilitator Superfamily
OGH68_RS35560	COG4249	Peptidase C14 caspase catalytic subunit p20
OGH68_RS35560	COG2319	Wd-40 repeat
OGH68_RS35580	COG3591	Belongs to the peptidase S1B family
OGH68_RS35580	COG1864	DNA RNA non-specific endonuclease
OGH68_RS35620	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OGH68_RS35640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OGH68_RS35685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OGH68_RS35695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OGH68_RS35700	COG4638	Rieske (2fe-2S)
OGH68_RS35720	COG0509	glycine decarboxylation via glycine cleavage system
OGH68_RS35725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OGH68_RS35730	COG1760	l-serine dehydratase
OGH68_RS35735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OGH68_RS35745	COG0438	transferase activity, transferring glycosyl groups
OGH68_RS35770	COG2146	nitrite reductase [NAD(P)H] activity
OGH68_RS35775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OGH68_RS35780	COG1414	Transcriptional regulator
OGH68_RS35795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OGH68_RS35825	COG2964	Protein conserved in bacteria
OGH68_RS35840	COG1028	Short-chain dehydrogenase reductase Sdr
OGH68_RS35895	COG0596	Alpha beta hydrolase
OGH68_RS35900	COG3903	Transcriptional regulator
OGH68_RS35900	COG3629	intracellular signal transduction
OGH68_RS35915	COG2197	response regulator
OGH68_RS35925	COG1136	(ABC) transporter
OGH68_RS35955	COG5002	protein histidine kinase activity
OGH68_RS35970	COG1136	(ABC) transporter
OGH68_RS35970	COG0577	efflux transmembrane transporter activity
OGH68_RS35975	COG1136	(ABC) transporter
OGH68_RS35975	COG0577	efflux transmembrane transporter activity
OGH68_RS35985	COG0783	Belongs to the Dps family