locus-tag	class	description
CGZ69_RS00125	COG0515	serine threonine protein kinase
CGZ69_RS00155	COG0515	serine threonine protein kinase
CGZ69_RS00155	COG2815	serine threonine protein kinase
CGZ69_RS00170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGZ69_RS00400	COG3209	COG3209 Rhs family protein
CGZ69_RS00635	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS00695	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS00700	COG2205	protein histidine kinase activity
CGZ69_RS00705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ69_RS00760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS00760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ69_RS00760	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGZ69_RS00770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ69_RS00775	COG2376	Dihydroxyacetone kinase
CGZ69_RS00780	COG1461	Dihydroxyacetone kinase
CGZ69_RS00785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ69_RS00785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS00790	COG2376	Dihydroxyacetone kinase
CGZ69_RS00795	COG1461	Dihydroxyacetone kinase
CGZ69_RS00810	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CGZ69_RS00810	COG1672	PFAM Archaeal ATPase
CGZ69_RS00860	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CGZ69_RS00900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGZ69_RS00990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGZ69_RS01045	COG3293	Transposase
CGZ69_RS01050	COG0539	negative regulation of cytoplasmic translation
CGZ69_RS01075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS01110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGZ69_RS01155	COG2318	DinB family
CGZ69_RS01180	COG0302	gtp cyclohydrolase
CGZ69_RS01200	COG3387	PFAM Glycoside hydrolase 15-related
CGZ69_RS01225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGZ69_RS01230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGZ69_RS01235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGZ69_RS01260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGZ69_RS01305	COG1309	transcriptional regulator
CGZ69_RS01315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGZ69_RS01320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ69_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS01390	COG0667	Aldo Keto reductase
CGZ69_RS01415	COG1620	l-lactate permease
CGZ69_RS01420	COG0247	lactate metabolic process
CGZ69_RS01425	COG1139	Iron-sulfur cluster binding protein
CGZ69_RS01430	COG1556	Lactate utilization protein
CGZ69_RS01440	COG2318	DinB family
CGZ69_RS01455	COG0784	Response regulator, receiver
CGZ69_RS01455	COG2205	protein histidine kinase activity
CGZ69_RS01455	COG5002	protein histidine kinase activity
CGZ69_RS01625	COG2130	NADP-dependent
CGZ69_RS01665	COG1278	Cold shock
CGZ69_RS01740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGZ69_RS01750	COG0640	Transcriptional regulator
CGZ69_RS01760	COG2072	flavoprotein involved in K transport
CGZ69_RS01790	COG1017	nitric oxide dioxygenase activity
CGZ69_RS01790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGZ69_RS01795	COG1959	2 iron, 2 sulfur cluster binding
CGZ69_RS01810	COG0714	Associated with various cellular activities
CGZ69_RS01830	COG1864	DNA RNA non-specific endonuclease
CGZ69_RS01830	COG3591	Belongs to the peptidase S1B family
CGZ69_RS01880	COG1966	Carbon starvation protein
CGZ69_RS01935	COG1940	carbohydrate kinase activity
CGZ69_RS01935	COG1846	Transcriptional regulator
CGZ69_RS01950	COG1175	transmembrane transport
CGZ69_RS01955	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS01960	COG0366	Alpha amylase catalytic
CGZ69_RS01975	COG5504	Zn-dependent protease
CGZ69_RS01980	COG0789	Transcriptional regulator
CGZ69_RS02010	COG1280	lysine exporter protein (LysE YggA)
CGZ69_RS02020	COG1316	TRANSCRIPTIONal
CGZ69_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGZ69_RS02035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGZ69_RS02080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CGZ69_RS02125	COG0363	glucosamine-6-phosphate deaminase activity
CGZ69_RS02130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS02140	COG1263	PTS System
CGZ69_RS02145	COG2188	Transcriptional regulator
CGZ69_RS02180	COG1881	PFAM PEBP family protein
CGZ69_RS02195	COG0252	asparaginase activity
CGZ69_RS02200	COG1027	Aspartate ammonia-lyase
CGZ69_RS02220	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CGZ69_RS02250	COG1609	Transcriptional regulator
CGZ69_RS02255	COG1609	Transcriptional regulator
CGZ69_RS02280	COG1621	beta-fructofuranosidase activity
CGZ69_RS02330	COG1295	ribonuclease BN
CGZ69_RS02370	COG1573	uracil-dna glycosylase
CGZ69_RS02565	COG0300	oxidoreductase activity
CGZ69_RS02600	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS02605	COG2366	antibiotic biosynthetic process
CGZ69_RS02620	COG2070	2-Nitropropane dioxygenase
CGZ69_RS02635	COG0515	serine threonine protein kinase
CGZ69_RS02660	COG0517	IMP dehydrogenase activity
CGZ69_RS02660	COG0516	GMP reductase activity
CGZ69_RS02700	COG0574	Belongs to the PEP-utilizing enzyme family
CGZ69_RS02700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS02720	COG0516	GMP reductase activity
CGZ69_RS02720	COG0517	IMP dehydrogenase activity
CGZ69_RS02785	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS02790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGZ69_RS02795	COG1024	Enoyl-CoA hydratase
CGZ69_RS02825	COG3285	dna ligase
CGZ69_RS02825	COG1793	dna ligase
CGZ69_RS02830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CGZ69_RS02860	COG0517	IMP dehydrogenase activity
CGZ69_RS02865	COG0693	protein deglycase activity
CGZ69_RS02895	COG0784	Response regulator, receiver
CGZ69_RS02895	COG2205	protein histidine kinase activity
CGZ69_RS02915	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS03040	COG1937	Protein conserved in bacteria
CGZ69_RS03050	COG0516	GMP reductase activity
CGZ69_RS03050	COG0517	IMP dehydrogenase activity
CGZ69_RS03080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS03085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ69_RS03090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGZ69_RS03090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGZ69_RS03090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CGZ69_RS03095	COG1105	Belongs to the carbohydrate kinase PfkB family
CGZ69_RS03100	COG1349	DNA-binding transcription factor activity
CGZ69_RS03120	COG0300	oxidoreductase activity
CGZ69_RS03135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGZ69_RS03175	COG0009	L-threonylcarbamoyladenylate synthase
CGZ69_RS03185	COG1309	transcriptional regulator
CGZ69_RS03195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGZ69_RS03200	COG0246	Mannitol dehydrogenase
CGZ69_RS03235	COG1609	Transcriptional regulator
CGZ69_RS03240	COG3842	ATPase activity
CGZ69_RS03245	COG1609	Transcriptional regulator
CGZ69_RS03255	COG1175	transmembrane transport
CGZ69_RS03280	COG1609	Transcriptional regulator
CGZ69_RS03285	COG1609	Transcriptional regulator
CGZ69_RS03305	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS03310	COG2376	Dihydroxyacetone kinase
CGZ69_RS03315	COG1461	Dihydroxyacetone kinase
CGZ69_RS03320	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGZ69_RS03325	COG0310	cobalt ion transport
CGZ69_RS03330	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CGZ69_RS03340	COG1122	ATPase activity
CGZ69_RS03345	COG2217	Heavy metal translocating P-type atpase
CGZ69_RS03350	COG0640	Transcriptional regulator
CGZ69_RS03360	COG0363	glucosamine-6-phosphate deaminase activity
CGZ69_RS03370	COG1335	isochorismatase
CGZ69_RS03375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS03455	COG0723	plastoquinol--plastocyanin reductase activity
CGZ69_RS03455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS03460	COG2080	2 iron, 2 sulfur cluster binding
CGZ69_RS03465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CGZ69_RS03470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGZ69_RS03565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGZ69_RS03570	COG0028	Belongs to the TPP enzyme family
CGZ69_RS03585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS03595	COG2208	phosphoserine phosphatase activity
CGZ69_RS03595	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS03595	COG2172	sigma factor antagonist activity
CGZ69_RS03620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ69_RS03640	COG2197	response regulator
CGZ69_RS03645	COG3851	Histidine kinase
CGZ69_RS03665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGZ69_RS03685	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS03695	COG0477	Major facilitator Superfamily
CGZ69_RS03700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGZ69_RS03705	COG1032	radical SAM domain protein
CGZ69_RS03720	COG3634	alkyl hydroperoxide reductase activity
CGZ69_RS03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS03780	COG0702	epimerase
CGZ69_RS03795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGZ69_RS03805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGZ69_RS03835	COG1120	ATPase activity
CGZ69_RS03840	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS03845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS03850	COG1132	(ABC) transporter
CGZ69_RS03855	COG1132	(ABC) transporter
CGZ69_RS03875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGZ69_RS03880	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CGZ69_RS03900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGZ69_RS03910	COG4264	IucA IucC family
CGZ69_RS03940	COG2814	Major facilitator Superfamily
CGZ69_RS03970	COG2226	methyltransferase
CGZ69_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS04090	COG1063	alcohol dehydrogenase
CGZ69_RS04115	COG1215	transferase activity, transferring glycosyl groups
CGZ69_RS04135	COG0464	growth
CGZ69_RS04145	COG1349	DNA-binding transcription factor activity
CGZ69_RS04195	COG1940	carbohydrate kinase activity
CGZ69_RS04200	COG2223	nitrite transmembrane transporter activity
CGZ69_RS04230	COG2197	response regulator
CGZ69_RS04235	COG4585	Histidine kinase
CGZ69_RS04255	COG0644	oxidoreductase
CGZ69_RS04270	COG1660	Displays ATPase and GTPase activities
CGZ69_RS04295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGZ69_RS04315	COG0204	Acyl-transferase
CGZ69_RS04345	COG0584	glycerophosphoryl diester phosphodiesterase
CGZ69_RS04365	COG0671	phosphoesterase, PA-phosphatase related
CGZ69_RS04375	COG1309	transcriptional regulator
CGZ69_RS04395	COG0640	Transcriptional regulator
CGZ69_RS04400	COG1902	pentaerythritol trinitrate reductase activity
CGZ69_RS04410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGZ69_RS04415	COG2971	BadF BadG BcrA BcrD
CGZ69_RS04425	COG2706	6-phosphogluconolactonase activity
CGZ69_RS04470	COG0500	methyltransferase
CGZ69_RS04495	COG2835	tetraacyldisaccharide 4'-kinase activity
CGZ69_RS04520	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGZ69_RS04530	COG2072	flavoprotein involved in K transport
CGZ69_RS04535	COG1132	(ABC) transporter
CGZ69_RS04545	COG1132	(ABC) transporter
CGZ69_RS04550	COG1132	(ABC) transporter
CGZ69_RS04560	COG2814	Major facilitator Superfamily
CGZ69_RS04570	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CGZ69_RS04575	COG0644	oxidoreductase
CGZ69_RS04610	COG0300	oxidoreductase activity
CGZ69_RS04665	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CGZ69_RS04670	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CGZ69_RS04675	COG2197	response regulator
CGZ69_RS04685	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CGZ69_RS04690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CGZ69_RS04690	COG0235	Class ii aldolase
CGZ69_RS04695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CGZ69_RS04695	COG0235	Class ii aldolase
CGZ69_RS04700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGZ69_RS04715	COG1104	cysteine desulfurase activity
CGZ69_RS04750	COG1946	Acyl-CoA thioesterase
CGZ69_RS04755	COG0386	Belongs to the glutathione peroxidase family
CGZ69_RS04760	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS04770	COG0242	peptide deformylase activity
CGZ69_RS04780	COG3442	glutamine amidotransferase
CGZ69_RS04785	COG0205	6-phosphofructokinase activity
CGZ69_RS04815	COG1957	nucleoside hydrolase
CGZ69_RS04860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGZ69_RS04870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CGZ69_RS04885	COG0204	Acyl-transferase
CGZ69_RS04895	COG0829	nickel cation binding
CGZ69_RS04905	COG0830	nickel cation binding
CGZ69_RS04910	COG0804	urea catabolic process
CGZ69_RS04915	COG0832	Belongs to the urease beta subunit family
CGZ69_RS04920	COG0831	urea catabolic process
CGZ69_RS04935	COG0740	serine-type endopeptidase activity
CGZ69_RS04945	COG0791	NLP P60 protein
CGZ69_RS04950	COG1280	lysine exporter protein (LysE YggA)
CGZ69_RS04970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGZ69_RS04975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGZ69_RS04980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CGZ69_RS05030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGZ69_RS05045	COG1940	carbohydrate kinase activity
CGZ69_RS05050	COG2188	Transcriptional regulator
CGZ69_RS05055	COG1595	DNA-templated transcription, initiation
CGZ69_RS05095	COG0626	cystathionine gamma-synthase activity
CGZ69_RS05115	COG1522	sequence-specific DNA binding
CGZ69_RS05120	COG0419	ATPase involved in DNA repair
CGZ69_RS05125	COG0420	3'-5' exonuclease activity
CGZ69_RS05130	COG1739	Uncharacterized protein family UPF0029
CGZ69_RS05135	COG1832	CoA-binding protein
CGZ69_RS05155	COG0110	maltose O-acetyltransferase activity
CGZ69_RS05190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGZ69_RS05205	COG1968	undecaprenyl-diphosphatase activity
CGZ69_RS05215	COG2813	Specifically methylates the guanine in position
CGZ69_RS05230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CGZ69_RS05250	COG2318	DinB family
CGZ69_RS05260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGZ69_RS05265	COG0747	negative chemotaxis
CGZ69_RS05315	COG2197	response regulator
CGZ69_RS05320	COG4585	Histidine kinase
CGZ69_RS05380	COG0697	spore germination
CGZ69_RS05400	COG1695	Transcriptional regulator
CGZ69_RS05405	COG0384	phenazine biosynthesis protein PhzF
CGZ69_RS05430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGZ69_RS05430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGZ69_RS05460	COG1716	ATPase activity
CGZ69_RS05480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CGZ69_RS05515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS05530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGZ69_RS05550	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CGZ69_RS05560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ69_RS05565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ69_RS05580	COG2018	Roadblock/LC7 domain
CGZ69_RS05615	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS05620	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS05645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGZ69_RS05660	COG2270	Major facilitator Superfamily
CGZ69_RS05670	COG3030	protein affecting phage T7 exclusion by the F plasmid
CGZ69_RS05675	COG1216	Glycosyl transferase, family 2
CGZ69_RS05700	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS05740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CGZ69_RS05745	COG0140	phosphoribosyl-ATP diphosphatase activity
CGZ69_RS05750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CGZ69_RS05755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGZ69_RS05755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGZ69_RS05760	COG3201	nicotinamide mononucleotide transporter
CGZ69_RS05785	COG1940	carbohydrate kinase activity
CGZ69_RS05785	COG1846	Transcriptional regulator
CGZ69_RS05790	COG0738	Major facilitator superfamily
CGZ69_RS05820	COG0531	amino acid
CGZ69_RS05840	COG1191	sigma factor activity
CGZ69_RS05850	COG2390	Transcriptional regulator
CGZ69_RS05855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGZ69_RS05860	COG3290	protein histidine kinase activity
CGZ69_RS05910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS05925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGZ69_RS05940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGZ69_RS05955	COG0194	GDP metabolic process
CGZ69_RS05965	COG0284	orotidine-5'-phosphate decarboxylase activity
CGZ69_RS05970	COG0167	dihydroorotate dehydrogenase activity
CGZ69_RS05980	COG0505	Belongs to the CarA family
CGZ69_RS05990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGZ69_RS06000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGZ69_RS06010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGZ69_RS06015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGZ69_RS06020	COG0006	proline dipeptidase activity
CGZ69_RS06030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CGZ69_RS06035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGZ69_RS06040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGZ69_RS06045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGZ69_RS06055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGZ69_RS06070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGZ69_RS06095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGZ69_RS06115	COG0124	histidyl-tRNA synthetase
CGZ69_RS06130	COG1196	nuclear chromosome segregation
CGZ69_RS06135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGZ69_RS06140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGZ69_RS06145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGZ69_RS06150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGZ69_RS06160	COG2255	four-way junction helicase activity
CGZ69_RS06165	COG0632	four-way junction helicase activity
CGZ69_RS06170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CGZ69_RS06175	COG0217	transcriptional regulatory protein
CGZ69_RS06180	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGZ69_RS06185	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGZ69_RS06195	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS06200	COG1560	Kdo2-lipid A biosynthetic process
CGZ69_RS06205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGZ69_RS06225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGZ69_RS06240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CGZ69_RS06300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGZ69_RS06360	COG1648	precorrin-2 dehydrogenase activity
CGZ69_RS06360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGZ69_RS06380	COG1464	Belongs to the NlpA lipoprotein family
CGZ69_RS06385	COG2011	ABC-type metal ion transport system permease component
CGZ69_RS06425	COG0584	glycerophosphoryl diester phosphodiesterase
CGZ69_RS06430	COG0204	Acyl-transferase
CGZ69_RS06430	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS06435	COG0477	Major facilitator Superfamily
CGZ69_RS06445	COG1819	glycosyl
CGZ69_RS06450	COG3973	AAA domain
CGZ69_RS06455	COG0165	Argininosuccinate lyase
CGZ69_RS06460	COG0137	argininosuccinate synthase activity
CGZ69_RS06475	COG1438	arginine binding
CGZ69_RS06480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGZ69_RS06485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGZ69_RS06490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CGZ69_RS06495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGZ69_RS06535	COG0697	spore germination
CGZ69_RS06545	COG1649	PFAM Uncharacterised BCR, COG1649
CGZ69_RS06565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGZ69_RS06565	COG0072	phenylalanine-tRNA ligase activity
CGZ69_RS06570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGZ69_RS06575	COG5002	protein histidine kinase activity
CGZ69_RS06580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGZ69_RS06585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGZ69_RS06590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CGZ69_RS06595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGZ69_RS06640	COG1846	Transcriptional regulator
CGZ69_RS06655	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS06670	COG0531	amino acid
CGZ69_RS06675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGZ69_RS06700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGZ69_RS06710	COG1595	DNA-templated transcription, initiation
CGZ69_RS06730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CGZ69_RS06770	COG0805	protein transport
CGZ69_RS06775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGZ69_RS06810	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGZ69_RS06820	COG1609	Transcriptional regulator
CGZ69_RS06825	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGZ69_RS06830	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGZ69_RS06845	COG4122	O-methyltransferase activity
CGZ69_RS06850	COG1222	aaa ATPase
CGZ69_RS06880	COG2197	response regulator
CGZ69_RS06885	COG0747	negative chemotaxis
CGZ69_RS06895	COG1410	methionine synthase
CGZ69_RS06895	COG0646	methionine synthase
CGZ69_RS06900	COG1414	Transcriptional regulator
CGZ69_RS06905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGZ69_RS06910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ69_RS06915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGZ69_RS06925	COG0215	cysteine-tRNA ligase activity
CGZ69_RS06940	COG0588	phosphoglycerate mutase activity
CGZ69_RS06945	COG0598	Magnesium transport protein CorA
CGZ69_RS06960	COG0667	Aldo Keto reductase
CGZ69_RS07015	COG0564	pseudouridine synthase activity
CGZ69_RS07030	COG1113	amino acid transport
CGZ69_RS07035	COG2186	Transcriptional regulator
CGZ69_RS07040	COG3265	gluconokinase activity
CGZ69_RS07060	COG3573	Dehydrogenase
CGZ69_RS07065	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGZ69_RS07070	COG2149	membrane
CGZ69_RS07095	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS07110	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS07125	COG3876	Protein conserved in bacteria
CGZ69_RS07150	COG0789	Transcriptional regulator
CGZ69_RS07170	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS07180	COG0640	Transcriptional regulator
CGZ69_RS07185	COG0697	spore germination
CGZ69_RS07190	COG0477	Major facilitator Superfamily
CGZ69_RS07205	COG3842	ATPase activity
CGZ69_RS07225	COG2851	Citrate transporter
CGZ69_RS07230	COG0243	molybdopterin cofactor binding
CGZ69_RS07240	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CGZ69_RS07245	COG2188	Transcriptional regulator
CGZ69_RS07285	COG2815	serine threonine protein kinase
CGZ69_RS07285	COG0515	serine threonine protein kinase
CGZ69_RS07290	COG2755	lipolytic protein G-D-S-L family
CGZ69_RS07305	COG1725	Transcriptional regulator
CGZ69_RS07335	COG4565	transcriptional regulatory protein
CGZ69_RS07355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGZ69_RS07365	COG0477	Major facilitator Superfamily
CGZ69_RS07370	COG1309	transcriptional regulator
CGZ69_RS07385	COG0596	Alpha beta hydrolase
CGZ69_RS07390	COG3903	Transcriptional regulator
CGZ69_RS07390	COG3629	intracellular signal transduction
CGZ69_RS07405	COG0641	radical SAM
CGZ69_RS07440	COG1799	cell septum assembly
CGZ69_RS07445	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS07450	COG0477	Major facilitator Superfamily
CGZ69_RS07455	COG0671	phosphoesterase, PA-phosphatase related
CGZ69_RS07475	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS07495	COG1160	GTP binding
CGZ69_RS07505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGZ69_RS07555	COG1187	pseudouridine synthase activity
CGZ69_RS07560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGZ69_RS07565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGZ69_RS07580	COG0686	Belongs to the AlaDH PNT family
CGZ69_RS07590	COG0494	nUDIX hydrolase
CGZ69_RS07595	COG0504	CTP synthase activity
CGZ69_RS07600	COG3387	PFAM Glycoside hydrolase 15-related
CGZ69_RS07630	COG2814	Major facilitator Superfamily
CGZ69_RS07675	COG0497	DNA recombination
CGZ69_RS07680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGZ69_RS07700	COG1120	ATPase activity
CGZ69_RS07705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS07710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS07715	COG0647	UMP catabolic process
CGZ69_RS07755	COG2094	Belongs to the DNA glycosylase MPG family
CGZ69_RS07765	COG1881	PFAM PEBP family protein
CGZ69_RS07790	COG1119	ATPase activity
CGZ69_RS07805	COG2197	response regulator
CGZ69_RS07810	COG4585	Histidine kinase
CGZ69_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS07820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CGZ69_RS07830	COG0842	Transport permease protein
CGZ69_RS07830	COG1131	(ABC) transporter
CGZ69_RS07830	COG1716	ATPase activity
CGZ69_RS07835	COG3830	Belongs to the UPF0237 family
CGZ69_RS07835	COG0560	Phosphoserine phosphatase
CGZ69_RS07855	COG2807	transmembrane transport
CGZ69_RS07860	COG2186	Transcriptional regulator
CGZ69_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS07890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGZ69_RS07910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CGZ69_RS07915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS07930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGZ69_RS07960	COG3387	PFAM Glycoside hydrolase 15-related
CGZ69_RS08010	COG0488	(ABC) transporter
CGZ69_RS08030	COG0235	Class ii aldolase
CGZ69_RS08050	COG1492	cobalamin metabolic process
CGZ69_RS08065	COG1797	cobyrinic acid a,c-diamide synthase activity
CGZ69_RS08095	COG1104	cysteine desulfurase activity
CGZ69_RS08110	COG1917	Cupin 2, conserved barrel domain protein
CGZ69_RS08115	COG5285	phytanoyl-CoA dioxygenase
CGZ69_RS08155	COG4585	Histidine kinase
CGZ69_RS08160	COG2197	response regulator
CGZ69_RS08165	COG0768	penicillin binding
CGZ69_RS08210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGZ69_RS08220	COG2171	N-acyltransferase activity
CGZ69_RS08240	COG0822	iron-sulfur transferase activity
CGZ69_RS08245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGZ69_RS08250	COG0396	ATPase activity
CGZ69_RS08260	COG0719	Fe-S assembly protein
CGZ69_RS08305	COG0109	protoheme IX farnesyltransferase activity
CGZ69_RS08315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGZ69_RS08330	COG0363	glucosamine-6-phosphate deaminase activity
CGZ69_RS08345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGZ69_RS08350	COG3903	Transcriptional regulator
CGZ69_RS08350	COG3629	intracellular signal transduction
CGZ69_RS08375	COG0604	alcohol dehydrogenase
CGZ69_RS08400	COG0604	alcohol dehydrogenase
CGZ69_RS08400	COG3321	synthase
CGZ69_RS08400	COG0604	alcohol dehydrogenase
CGZ69_RS08400	COG3321	synthase
CGZ69_RS08405	COG0604	alcohol dehydrogenase
CGZ69_RS08405	COG3321	synthase
CGZ69_RS08420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS08430	COG2181	nitrate reductase activity
CGZ69_RS08430	COG0247	lactate metabolic process
CGZ69_RS08435	COG0166	Belongs to the GPI family
CGZ69_RS08445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGZ69_RS08455	COG0126	phosphoglycerate kinase activity
CGZ69_RS08460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGZ69_RS08470	COG1481	regulation of sporulation
CGZ69_RS08475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CGZ69_RS08480	COG1660	Displays ATPase and GTPase activities
CGZ69_RS08485	COG0322	excinuclease ABC activity
CGZ69_RS08500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGZ69_RS08535	COG0556	nucleotide-excision repair
CGZ69_RS08545	COG0584	glycerophosphoryl diester phosphodiesterase
CGZ69_RS08550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGZ69_RS08555	COG0477	Major facilitator Superfamily
CGZ69_RS08560	COG2313	pseudouridylate synthase activity
CGZ69_RS08580	COG0436	Aminotransferase
CGZ69_RS08585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGZ69_RS08610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGZ69_RS08615	COG0330	HflC and HflK could
CGZ69_RS08630	COG0237	dephospho-CoA kinase activity
CGZ69_RS08645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGZ69_RS08645	COG0596	Alpha beta hydrolase
CGZ69_RS08645	COG2226	methyltransferase
CGZ69_RS08650	COG1643	Atp-dependent helicase
CGZ69_RS08680	COG2050	protein possibly involved in aromatic compounds catabolism
CGZ69_RS08730	COG0737	Belongs to the 5'-nucleotidase family
CGZ69_RS08750	COG0287	Prephenate dehydrogenase
CGZ69_RS08750	COG1605	Chorismate mutase
CGZ69_RS08775	COG0513	Belongs to the DEAD box helicase family
CGZ69_RS08780	COG1278	Cold shock
CGZ69_RS08800	COG0069	glutamate synthase activity
CGZ69_RS08800	COG0067	glutamate synthase
CGZ69_RS08800	COG0070	glutamate synthase
CGZ69_RS08830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGZ69_RS08835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGZ69_RS08855	COG0159	tryptophan synthase activity
CGZ69_RS08870	COG0134	indole-3-glycerol-phosphate synthase activity
CGZ69_RS08895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CGZ69_RS08910	COG2508	Transcriptional regulator
CGZ69_RS08920	COG0107	imidazoleglycerol-phosphate synthase activity
CGZ69_RS08925	COG0251	oxidation-reduction process
CGZ69_RS08930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGZ69_RS08935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGZ69_RS08940	COG0131	Imidazoleglycerol-phosphate dehydratase
CGZ69_RS08945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGZ69_RS08950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGZ69_RS08990	COG1432	Conserved Protein
CGZ69_RS08995	COG0587	DNA-directed DNA polymerase activity
CGZ69_RS09045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGZ69_RS09055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGZ69_RS09070	COG1799	cell septum assembly
CGZ69_RS09075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGZ69_RS09080	COG1496	oxidoreductase activity
CGZ69_RS09095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CGZ69_RS09100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGZ69_RS09110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGZ69_RS09115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGZ69_RS09120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CGZ69_RS09125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGZ69_RS09140	COG0275	rRNA processing
CGZ69_RS09150	COG0714	Associated with various cellular activities
CGZ69_RS09180	COG3842	ATPase activity
CGZ69_RS09190	COG1309	transcriptional regulator
CGZ69_RS09235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS09235	COG2022	thiamine diphosphate biosynthetic process
CGZ69_RS09245	COG2022	thiamine diphosphate biosynthetic process
CGZ69_RS09250	COG0515	serine threonine protein kinase
CGZ69_RS09250	COG2815	serine threonine protein kinase
CGZ69_RS09255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CGZ69_RS09265	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CGZ69_RS09270	COG2193	ferroxidase activity
CGZ69_RS09280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CGZ69_RS09290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGZ69_RS09295	COG0205	6-phosphofructokinase activity
CGZ69_RS09300	COG2197	response regulator
CGZ69_RS09305	COG4585	Histidine kinase
CGZ69_RS09340	COG0003	Pfam Anion-transporting ATPase
CGZ69_RS09360	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS09415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGZ69_RS09420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CGZ69_RS09425	COG0723	plastoquinol--plastocyanin reductase activity
CGZ69_RS09430	COG2010	Cytochrome c
CGZ69_RS09435	COG1845	cytochrome c oxidase, subunit III
CGZ69_RS09445	COG1376	ErfK ybiS ycfS ynhG family protein
CGZ69_RS09460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CGZ69_RS09465	COG1104	cysteine desulfurase activity
CGZ69_RS09470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGZ69_RS09490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGZ69_RS09495	COG2197	response regulator
CGZ69_RS09500	COG4585	Histidine kinase
CGZ69_RS09525	COG1132	(ABC) transporter
CGZ69_RS09530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGZ69_RS09545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CGZ69_RS09555	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CGZ69_RS09560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGZ69_RS09565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGZ69_RS09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ69_RS09580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGZ69_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS09630	COG0321	lipoyl(octanoyl) transferase activity
CGZ69_RS09635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGZ69_RS09690	COG0366	Alpha amylase catalytic
CGZ69_RS09705	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS09740	COG2365	Tyrosine phosphatase family
CGZ69_RS09760	COG1609	Transcriptional regulator
CGZ69_RS09770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CGZ69_RS09795	COG0174	glutamine synthetase
CGZ69_RS09825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGZ69_RS09825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CGZ69_RS09830	COG2814	Major facilitator Superfamily
CGZ69_RS09840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CGZ69_RS09850	COG1994	Peptidase M50
CGZ69_RS09920	COG2814	Major facilitator Superfamily
CGZ69_RS09935	COG3540	Alkaline phosphatase
CGZ69_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS09970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CGZ69_RS09985	COG2201	protein-glutamate methylesterase activity
CGZ69_RS09990	COG4191	Histidine kinase
CGZ69_RS10125	COG0305	Participates in initiation and elongation during chromosome replication
CGZ69_RS10240	COG1484	DNA-dependent DNA replication
CGZ69_RS10370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGZ69_RS10430	COG0557	exoribonuclease II activity
CGZ69_RS10435	COG3022	response to hydroperoxide
CGZ69_RS10440	COG0800	Aldolase
CGZ69_RS10460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGZ69_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS10480	COG2030	dehydratase
CGZ69_RS10490	COG2197	response regulator
CGZ69_RS10540	COG0860	N-Acetylmuramoyl-L-alanine amidase
CGZ69_RS10550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS10570	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS10575	COG1309	transcriptional regulator
CGZ69_RS10615	COG0183	Belongs to the thiolase family
CGZ69_RS10620	COG2124	cytochrome p450
CGZ69_RS10640	COG4122	O-methyltransferase activity
CGZ69_RS10675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ69_RS10730	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CGZ69_RS10845	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CGZ69_RS10990	COG1358	cellular component organization or biogenesis
CGZ69_RS11035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGZ69_RS11040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGZ69_RS11050	COG0477	Major facilitator Superfamily
CGZ69_RS11055	COG1309	transcriptional regulator
CGZ69_RS11070	COG0667	Aldo Keto reductase
CGZ69_RS11075	COG0789	Transcriptional regulator
CGZ69_RS11080	COG0113	porphobilinogen synthase activity
CGZ69_RS11090	COG0181	hydroxymethylbilane synthase activity
CGZ69_RS11110	COG2205	protein histidine kinase activity
CGZ69_RS11115	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS11130	COG1376	ErfK ybiS ycfS ynhG family protein
CGZ69_RS11155	COG1741	Belongs to the pirin family
CGZ69_RS11170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ69_RS11175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ69_RS11180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS11215	COG1764	response to oxidative stress
CGZ69_RS11220	COG2130	NADP-dependent
CGZ69_RS11245	COG1077	Cell shape determining protein MreB Mrl
CGZ69_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS11260	COG0825	malonyl-CoA metabolic process
CGZ69_RS11260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CGZ69_RS11305	COG1335	isochorismatase
CGZ69_RS11355	COG1070	Carbohydrate kinase
CGZ69_RS11370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGZ69_RS11385	COG0358	DNA primase activity
CGZ69_RS11395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CGZ69_RS11420	COG0243	molybdopterin cofactor binding
CGZ69_RS11460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGZ69_RS11475	COG0697	spore germination
CGZ69_RS11500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGZ69_RS11500	COG0574	Belongs to the PEP-utilizing enzyme family
CGZ69_RS11520	COG0423	glycine-tRNA ligase activity
CGZ69_RS11525	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGZ69_RS11525	COG3443	Belongs to the bacterial solute-binding protein 9 family
CGZ69_RS11530	COG1121	(ABC) transporter
CGZ69_RS11535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGZ69_RS11555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGZ69_RS11560	COG1381	Involved in DNA repair and RecF pathway recombination
CGZ69_RS11575	COG2197	response regulator
CGZ69_RS11580	COG4585	Histidine kinase
CGZ69_RS11585	COG2409	Drug exporters of the RND superfamily
CGZ69_RS11595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGZ69_RS11615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGZ69_RS11635	COG2315	Protein conserved in bacteria
CGZ69_RS11645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGZ69_RS11655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGZ69_RS11670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGZ69_RS11675	COG1234	tRNA 3'-trailer cleavage
CGZ69_RS11680	COG0537	adenosine 5'-monophosphoramidase activity
CGZ69_RS11705	COG0484	heat shock protein binding
CGZ69_RS11710	COG1420	regulation of RNA biosynthetic process
CGZ69_RS11740	COG0481	GTPase activity
CGZ69_RS11745	COG0268	Binds directly to 16S ribosomal RNA
CGZ69_RS11800	COG1555	photosystem II stabilization
CGZ69_RS11805	COG1307	EDD domain protein, DegV family
CGZ69_RS11825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CGZ69_RS11845	COG0588	phosphoglycerate mutase activity
CGZ69_RS11850	COG0799	negative regulation of ribosome biogenesis
CGZ69_RS11860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGZ69_RS11870	COG0501	Belongs to the peptidase M48B family
CGZ69_RS11885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGZ69_RS11895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGZ69_RS11910	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CGZ69_RS11935	COG1215	transferase activity, transferring glycosyl groups
CGZ69_RS11950	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS11955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGZ69_RS11960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CGZ69_RS11965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CGZ69_RS11980	COG1530	ribonuclease E activity
CGZ69_RS12065	COG0772	Belongs to the SEDS family
CGZ69_RS12085	COG1077	Cell shape determining protein MreB Mrl
CGZ69_RS12090	COG0105	UTP biosynthetic process
CGZ69_RS12100	COG0285	dihydrofolate synthase activity
CGZ69_RS12105	COG0525	valine-tRNA ligase activity
CGZ69_RS12115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGZ69_RS12120	COG0740	serine-type endopeptidase activity
CGZ69_RS12125	COG0740	serine-type endopeptidase activity
CGZ69_RS12130	COG0544	peptidyl-prolyl cis-trans isomerase activity
CGZ69_RS12150	COG3594	Acyltransferase
CGZ69_RS12155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGZ69_RS12205	COG1113	amino acid transport
CGZ69_RS12210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGZ69_RS12215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGZ69_RS12250	COG5002	protein histidine kinase activity
CGZ69_RS12275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGZ69_RS12280	COG2124	cytochrome p450
CGZ69_RS12305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGZ69_RS12315	COG0668	transmembrane transport
CGZ69_RS12325	COG1653	transport
CGZ69_RS12330	COG1175	transmembrane transport
CGZ69_RS12335	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS12340	COG1486	melibiose metabolic process
CGZ69_RS12355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ69_RS12405	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS12415	COG0577	efflux transmembrane transporter activity
CGZ69_RS12415	COG1136	(ABC) transporter
CGZ69_RS12440	COG0629	single-stranded DNA binding
CGZ69_RS12495	COG1131	(ABC) transporter
CGZ69_RS12510	COG3962	Belongs to the TPP enzyme family
CGZ69_RS12540	COG2409	Drug exporters of the RND superfamily
CGZ69_RS12565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGZ69_RS12570	COG0515	serine threonine protein kinase
CGZ69_RS12580	COG2115	Belongs to the xylose isomerase family
CGZ69_RS12590	COG0673	inositol 2-dehydrogenase activity
CGZ69_RS12595	COG1609	Transcriptional regulator
CGZ69_RS12610	COG0456	acetyltransferase
CGZ69_RS12610	COG1846	Transcriptional regulator
CGZ69_RS12635	COG0697	spore germination
CGZ69_RS12645	COG1472	Belongs to the glycosyl hydrolase 3 family
CGZ69_RS12690	COG0028	Belongs to the TPP enzyme family
CGZ69_RS12700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS12735	COG1946	Acyl-CoA thioesterase
CGZ69_RS12740	COG4585	Histidine kinase
CGZ69_RS12745	COG2197	response regulator
CGZ69_RS12760	COG1309	transcriptional regulator
CGZ69_RS12765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS12780	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS12790	COG2375	cellular response to nickel ion
CGZ69_RS12810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGZ69_RS12820	COG0589	response to stress
CGZ69_RS12830	COG4977	sequence-specific DNA binding
CGZ69_RS12835	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CGZ69_RS12940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS12960	COG0154	amidase activity
CGZ69_RS12970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ69_RS12975	COG0765	amino acid transport
CGZ69_RS12980	COG0765	amino acid transport
CGZ69_RS12985	COG1126	abc transporter atp-binding protein
CGZ69_RS13055	COG1940	carbohydrate kinase activity
CGZ69_RS13060	COG0673	inositol 2-dehydrogenase activity
CGZ69_RS13065	COG4702	Belongs to the UPF0303 family
CGZ69_RS13075	COG1742	UPF0060 membrane protein
CGZ69_RS13080	COG0706	membrane insertase activity
CGZ69_RS13080	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
CGZ69_RS13090	COG4213	ABC transporter substrate-binding protein
CGZ69_RS13095	COG3764	Sortase (surface protein transpeptidase)
CGZ69_RS13150	COG2733	membrane
CGZ69_RS13180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ69_RS13190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGZ69_RS13215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGZ69_RS13225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGZ69_RS13230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CGZ69_RS13235	COG1263	PTS System
CGZ69_RS13240	COG1263	PTS System
CGZ69_RS13245	COG1234	tRNA 3'-trailer cleavage
CGZ69_RS13275	COG1113	amino acid transport
CGZ69_RS13280	COG1115	amino acid carrier protein
CGZ69_RS13290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CGZ69_RS13300	COG1335	isochorismatase
CGZ69_RS13335	COG0277	FAD linked oxidase domain protein
CGZ69_RS13345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CGZ69_RS13385	COG3654	unkown
CGZ69_RS13435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGZ69_RS13440	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS13445	COG1175	transmembrane transport
CGZ69_RS13450	COG1653	transport
CGZ69_RS13460	COG1678	Uncharacterized ACR, COG1678
CGZ69_RS13465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGZ69_RS13470	COG0776	regulation of translation
CGZ69_RS13485	COG3973	AAA domain
CGZ69_RS13485	COG3973	AAA domain
CGZ69_RS13535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGZ69_RS13540	COG0793	Belongs to the peptidase S41A family
CGZ69_RS13545	COG2177	Part of the ABC transporter FtsEX involved in
CGZ69_RS13550	COG2884	Cell division ATP-binding protein ftsE
CGZ69_RS13565	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGZ69_RS13570	COG0515	serine threonine protein kinase
CGZ69_RS13575	COG0515	serine threonine protein kinase
CGZ69_RS13580	COG1674	ftsk spoiiie
CGZ69_RS13590	COG1175	transmembrane transport
CGZ69_RS13595	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS13600	COG0463	Glycosyl transferase, family 2
CGZ69_RS13600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGZ69_RS13605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGZ69_RS13625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CGZ69_RS13630	COG1309	transcriptional regulator
CGZ69_RS13640	COG1134	teichoic acid transport
CGZ69_RS13640	COG1388	LysM domain
CGZ69_RS13650	COG2902	Dehydrogenase
CGZ69_RS13675	COG0653	protein targeting
CGZ69_RS13685	COG3214	Protein conserved in bacteria
CGZ69_RS13695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGZ69_RS13705	COG0823	Involved in the tonB-independent uptake of proteins
CGZ69_RS13710	COG5000	phosphorelay sensor kinase activity
CGZ69_RS13710	COG5002	protein histidine kinase activity
CGZ69_RS13715	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS13720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CGZ69_RS13740	COG0714	Associated with various cellular activities
CGZ69_RS13785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CGZ69_RS13800	COG1482	cell wall glycoprotein biosynthetic process
CGZ69_RS13810	COG2835	tetraacyldisaccharide 4'-kinase activity
CGZ69_RS13815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGZ69_RS13855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CGZ69_RS13860	COG0778	Nitroreductase
CGZ69_RS13860	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CGZ69_RS13890	COG1316	TRANSCRIPTIONal
CGZ69_RS13895	COG1316	TRANSCRIPTIONal
CGZ69_RS13915	COG1316	TRANSCRIPTIONal
CGZ69_RS13930	COG1595	DNA-templated transcription, initiation
CGZ69_RS13935	COG0702	epimerase
CGZ69_RS13945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGZ69_RS13970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGZ69_RS13985	COG2205	protein histidine kinase activity
CGZ69_RS13990	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS13995	COG3104	oligopeptide transport
CGZ69_RS14025	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS14030	COG1191	sigma factor activity
CGZ69_RS14050	COG1794	racemase activity, acting on amino acids and derivatives
CGZ69_RS14060	COG1228	amidohydrolase
CGZ69_RS14075	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGZ69_RS14090	COG0531	amino acid
CGZ69_RS14135	COG2755	lipolytic protein G-D-S-L family
CGZ69_RS14140	COG0183	Belongs to the thiolase family
CGZ69_RS14175	COG0577	efflux transmembrane transporter activity
CGZ69_RS14175	COG1136	(ABC) transporter
CGZ69_RS14180	COG1136	(ABC) transporter
CGZ69_RS14180	COG0577	efflux transmembrane transporter activity
CGZ69_RS14185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CGZ69_RS14190	COG1252	NADH dehydrogenase
CGZ69_RS14200	COG1733	regulation of RNA biosynthetic process
CGZ69_RS14225	COG0148	phosphopyruvate hydratase activity
CGZ69_RS14345	COG0577	efflux transmembrane transporter activity
CGZ69_RS14350	COG1136	(ABC) transporter
CGZ69_RS14355	COG2814	Major facilitator Superfamily
CGZ69_RS14365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS14390	COG4585	Histidine kinase
CGZ69_RS14405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGZ69_RS14410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGZ69_RS14415	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS14420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGZ69_RS14425	COG0193	aminoacyl-tRNA hydrolase activity
CGZ69_RS14445	COG1674	ftsk spoiiie
CGZ69_RS14450	COG0747	negative chemotaxis
CGZ69_RS14455	COG0697	spore germination
CGZ69_RS14460	COG1522	sequence-specific DNA binding
CGZ69_RS14465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGZ69_RS14480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGZ69_RS14500	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CGZ69_RS14505	COG1605	Chorismate mutase
CGZ69_RS14620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CGZ69_RS14635	COG4106	trans-aconitate 2-methyltransferase activity
CGZ69_RS14640	COG1846	Transcriptional regulator
CGZ69_RS14645	COG2197	response regulator
CGZ69_RS14650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGZ69_RS14680	COG0488	(ABC) transporter
CGZ69_RS14690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGZ69_RS14695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CGZ69_RS14705	COG0084	hydrolase, TatD family'
CGZ69_RS14735	COG3739	integral membrane protein
CGZ69_RS14740	COG0768	penicillin binding
CGZ69_RS14755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGZ69_RS14760	COG1764	response to oxidative stress
CGZ69_RS14770	COG1122	ATPase activity
CGZ69_RS14780	COG0310	cobalt ion transport
CGZ69_RS14790	COG2409	Drug exporters of the RND superfamily
CGZ69_RS14800	COG4946	Tricorn protease homolog
CGZ69_RS14800	COG0793	Belongs to the peptidase S41A family
CGZ69_RS14810	COG2072	flavoprotein involved in K transport
CGZ69_RS14815	COG2267	carboxylic ester hydrolase activity
CGZ69_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS14855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS14860	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGZ69_RS14865	COG0315	cyclic pyranopterin monophosphate synthase activity
CGZ69_RS14875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGZ69_RS14880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGZ69_RS14910	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CGZ69_RS14920	COG1970	mechanosensitive ion channel activity
CGZ69_RS14945	COG0477	Major facilitator Superfamily
CGZ69_RS14960	COG1247	-acetyltransferase
CGZ69_RS14965	COG3384	dioxygenase
CGZ69_RS14970	COG1846	Transcriptional regulator
CGZ69_RS14995	COG1454	alcohol dehydrogenase
CGZ69_RS15015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CGZ69_RS15110	COG2132	Multicopper oxidase
CGZ69_RS15155	COG3387	PFAM Glycoside hydrolase 15-related
CGZ69_RS15205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGZ69_RS15285	COG0736	holo-[acyl-carrier-protein] synthase activity
CGZ69_RS15290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGZ69_RS15295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS15300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGZ69_RS15305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS15310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS15330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ69_RS15335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ69_RS15340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGZ69_RS15345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGZ69_RS15375	COG0477	Major facilitator Superfamily
CGZ69_RS15410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGZ69_RS15450	COG1686	Belongs to the peptidase S11 family
CGZ69_RS15475	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS15485	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CGZ69_RS15600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGZ69_RS15605	COG1280	lysine exporter protein (LysE YggA)
CGZ69_RS15620	COG0726	polysaccharide deacetylase
CGZ69_RS15635	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS15660	COG1309	transcriptional regulator
CGZ69_RS15710	COG2072	flavoprotein involved in K transport
CGZ69_RS15720	COG1024	Enoyl-CoA hydratase
CGZ69_RS15745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CGZ69_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS15765	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS15770	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS15780	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS15790	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS15850	COG0596	Alpha beta hydrolase
CGZ69_RS15850	COG2945	thiolester hydrolase activity
CGZ69_RS15860	COG4821	SIS domain
CGZ69_RS15870	COG0259	pyridoxamine-phosphate oxidase activity
CGZ69_RS15905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS15925	COG1487	ribonuclease activity
CGZ69_RS15935	COG5006	permease, DMT superfamily
CGZ69_RS15940	COG0583	DNA-binding transcription factor activity
CGZ69_RS15950	COG0247	lactate metabolic process
CGZ69_RS15950	COG0277	FAD linked oxidase domain protein
CGZ69_RS15960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CGZ69_RS15995	COG4106	trans-aconitate 2-methyltransferase activity
CGZ69_RS16060	COG2356	endonuclease I
CGZ69_RS16065	COG0667	Aldo Keto reductase
CGZ69_RS16080	COG0667	Aldo Keto reductase
CGZ69_RS16105	COG2252	PERMEase
CGZ69_RS16115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGZ69_RS16155	COG2226	methyltransferase
CGZ69_RS16180	COG2814	Major facilitator Superfamily
CGZ69_RS16190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGZ69_RS16195	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CGZ69_RS16200	COG1278	Cold shock
CGZ69_RS16215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS16220	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS16225	COG1120	ATPase activity
CGZ69_RS16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGZ69_RS16250	COG1061	Type III restriction enzyme res subunit
CGZ69_RS16260	COG3973	AAA domain
CGZ69_RS16295	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CGZ69_RS16300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGZ69_RS16330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CGZ69_RS16335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGZ69_RS16335	COG0515	serine threonine protein kinase
CGZ69_RS16390	COG0463	Glycosyl transferase, family 2
CGZ69_RS16400	COG1877	trehalose-phosphatase activity
CGZ69_RS16400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ69_RS16420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGZ69_RS16430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGZ69_RS16435	COG1105	Belongs to the carbohydrate kinase PfkB family
CGZ69_RS16450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGZ69_RS16455	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGZ69_RS16475	COG4251	negative regulation of phosphorylation
CGZ69_RS16480	COG2197	response regulator
CGZ69_RS16520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS16535	COG3842	ATPase activity
CGZ69_RS16545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGZ69_RS16555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGZ69_RS16560	COG0215	cysteine-tRNA ligase activity
CGZ69_RS16565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CGZ69_RS16570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CGZ69_RS16575	COG1329	Transcriptional regulator
CGZ69_RS16595	COG5002	protein histidine kinase activity
CGZ69_RS16610	COG0588	phosphoglycerate mutase activity
CGZ69_RS16625	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS16675	COG0667	Aldo Keto reductase
CGZ69_RS16680	COG3973	AAA domain
CGZ69_RS16715	COG2188	Transcriptional regulator
CGZ69_RS16720	COG4552	Acetyltransferase involved in intracellular survival and related
CGZ69_RS16735	COG1490	D-aminoacyl-tRNA deacylase activity
CGZ69_RS16740	COG0354	folic acid binding
CGZ69_RS16750	COG3485	protocatechuate 3,4-dioxygenase
CGZ69_RS16790	COG2897	thiosulfate sulfurtransferase activity
CGZ69_RS16815	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS16820	COG1609	Transcriptional regulator
CGZ69_RS16840	COG0488	(ABC) transporter
CGZ69_RS16840	COG0488	(ABC) transporter
CGZ69_RS16855	COG0737	Belongs to the 5'-nucleotidase family
CGZ69_RS16860	COG0456	acetyltransferase
CGZ69_RS16865	COG1725	Transcriptional regulator
CGZ69_RS16870	COG1116	anion transmembrane transporter activity
CGZ69_RS16890	COG0494	nUDIX hydrolase
CGZ69_RS16890	COG0406	alpha-ribazole phosphatase activity
CGZ69_RS16895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CGZ69_RS16910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGZ69_RS16915	COG0306	phosphate transporter
CGZ69_RS16925	COG1937	Protein conserved in bacteria
CGZ69_RS16940	COG0277	FAD linked oxidase domain protein
CGZ69_RS16965	COG0671	phosphoesterase, PA-phosphatase related
CGZ69_RS16970	COG1196	nuclear chromosome segregation
CGZ69_RS16970	COG0741	lytic transglycosylase activity
CGZ69_RS16970	COG0739	heme binding
CGZ69_RS17035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGZ69_RS17075	COG1131	(ABC) transporter
CGZ69_RS17085	COG4585	Histidine kinase
CGZ69_RS17090	COG2197	response regulator
CGZ69_RS17115	COG1846	Transcriptional regulator
CGZ69_RS17130	COG1252	NADH dehydrogenase
CGZ69_RS17155	COG0579	oxidoreductase
CGZ69_RS17160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CGZ69_RS17170	COG0741	lytic transglycosylase activity
CGZ69_RS17170	COG0739	heme binding
CGZ69_RS17170	COG1196	nuclear chromosome segregation
CGZ69_RS17190	COG4106	trans-aconitate 2-methyltransferase activity
CGZ69_RS17230	COG0513	Belongs to the DEAD box helicase family
CGZ69_RS17240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGZ69_RS17245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGZ69_RS17275	COG4232	protein-disulfide reductase activity
CGZ69_RS17280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CGZ69_RS17280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CGZ69_RS17290	COG1643	Atp-dependent helicase
CGZ69_RS17315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGZ69_RS17325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CGZ69_RS17345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGZ69_RS17350	COG0047	phosphoribosylformylglycinamidine synthase activity
CGZ69_RS17355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGZ69_RS17390	COG2197	response regulator
CGZ69_RS17400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGZ69_RS17415	COG0151	Belongs to the GarS family
CGZ69_RS17450	COG4941	Belongs to the sigma-70 factor family
CGZ69_RS17475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGZ69_RS17505	COG1191	sigma factor activity
CGZ69_RS17510	COG1191	sigma factor activity
CGZ69_RS17530	COG0477	Major facilitator Superfamily
CGZ69_RS17540	COG3467	pyridoxamine 5'-phosphate
CGZ69_RS17550	COG0477	Major facilitator Superfamily
CGZ69_RS17555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGZ69_RS17555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CGZ69_RS17565	COG2205	protein histidine kinase activity
CGZ69_RS17570	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS17580	COG1404	Belongs to the peptidase S8 family
CGZ69_RS17590	COG2329	Antibiotic biosynthesis monooxygenase
CGZ69_RS17615	COG0784	Response regulator, receiver
CGZ69_RS17620	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS17625	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS17630	COG1595	DNA-templated transcription, initiation
CGZ69_RS17670	COG3548	integral membrane protein
CGZ69_RS17705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGZ69_RS17720	COG0653	protein targeting
CGZ69_RS17735	COG0006	proline dipeptidase activity
CGZ69_RS17755	COG1999	signal sequence binding
CGZ69_RS17765	COG2372	response to copper ion
CGZ69_RS17770	COG2837	iron assimilation
CGZ69_RS17780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGZ69_RS17785	COG0561	phosphatase activity
CGZ69_RS17820	COG0789	Transcriptional regulator
CGZ69_RS17825	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CGZ69_RS17835	COG0561	phosphatase activity
CGZ69_RS17840	COG1196	nuclear chromosome segregation
CGZ69_RS17840	COG0741	lytic transglycosylase activity
CGZ69_RS17840	COG0739	heme binding
CGZ69_RS17850	COG4988	ABC transporter
CGZ69_RS17855	COG1294	oxidase, subunit
CGZ69_RS17860	COG1271	oxidase subunit
CGZ69_RS17865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGZ69_RS17870	COG1609	Transcriptional regulator
CGZ69_RS17890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGZ69_RS17915	COG0662	Cupin 2, conserved barrel domain protein
CGZ69_RS17920	COG1950	PFAM Membrane protein of
CGZ69_RS17925	COG0626	cystathionine gamma-synthase activity
CGZ69_RS17965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGZ69_RS17980	COG0534	Mate efflux family protein
CGZ69_RS17985	COG0359	binds to the 23S rRNA
CGZ69_RS17990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGZ69_RS17995	COG0629	single-stranded DNA binding
CGZ69_RS18000	COG0360	Binds together with S18 to 16S ribosomal RNA
CGZ69_RS18030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ69_RS18055	COG0617	tRNA 3'-terminal CCA addition
CGZ69_RS18070	COG0515	serine threonine protein kinase
CGZ69_RS18070	COG2815	serine threonine protein kinase
CGZ69_RS18075	COG1595	DNA-templated transcription, initiation
CGZ69_RS18085	COG0492	ferredoxin-NADP+ reductase activity
CGZ69_RS18090	COG3118	belongs to the thioredoxin family
CGZ69_RS18105	COG1192	Involved in chromosome partitioning
CGZ69_RS18110	COG0357	Ribosomal RNA small subunit methyltransferase G
CGZ69_RS18120	COG0706	membrane insertase activity
CGZ69_RS18125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CGZ69_RS18130	COG0594	ribonuclease P activity
CGZ69_RS18150	COG0592	DNA-directed DNA polymerase activity
CGZ69_RS18155	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CGZ69_RS18160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGZ69_RS18165	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CGZ69_RS18230	COG0705	Rhomboid family
CGZ69_RS18230	COG0457	Tetratricopeptide repeat
CGZ69_RS18245	COG3764	Sortase (surface protein transpeptidase)
CGZ69_RS18260	COG3764	Sortase (surface protein transpeptidase)
CGZ69_RS18265	COG3764	Sortase (surface protein transpeptidase)
CGZ69_RS18270	COG0515	serine threonine protein kinase
CGZ69_RS18275	COG0768	penicillin binding
CGZ69_RS18290	COG1716	ATPase activity
CGZ69_RS18295	COG1716	ATPase activity
CGZ69_RS18325	COG2255	four-way junction helicase activity
CGZ69_RS18340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGZ69_RS18350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGZ69_RS18355	COG2151	metal-sulfur cluster biosynthetic enzyme
CGZ69_RS18360	COG3396	Phenylacetate-CoA oxygenase
CGZ69_RS18365	COG3460	Phenylacetate-CoA oxygenase
CGZ69_RS18370	COG3396	Phenylacetate-CoA oxygenase
CGZ69_RS18395	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS18400	COG1309	transcriptional regulator
CGZ69_RS18405	COG1522	sequence-specific DNA binding
CGZ69_RS18420	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ69_RS18430	COG0303	'Molybdopterin
CGZ69_RS18435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGZ69_RS18455	COG1136	(ABC) transporter
CGZ69_RS18455	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGZ69_RS18495	COG0022	dehydrogenase e1 component
CGZ69_RS18500	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ69_RS18510	COG2271	Major facilitator Superfamily
CGZ69_RS18535	COG1362	aminopeptidase activity
CGZ69_RS18540	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS18565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGZ69_RS18600	COG1289	transmembrane transporter activity
CGZ69_RS18630	COG0789	Transcriptional regulator
CGZ69_RS18655	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGZ69_RS18655	COG1902	pentaerythritol trinitrate reductase activity
CGZ69_RS18680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGZ69_RS18715	COG0640	Transcriptional regulator
CGZ69_RS18750	COG0513	Belongs to the DEAD box helicase family
CGZ69_RS18755	COG1278	Cold shock
CGZ69_RS18770	COG1132	(ABC) transporter
CGZ69_RS18790	COG0596	Alpha beta hydrolase
CGZ69_RS18815	COG1131	(ABC) transporter
CGZ69_RS18885	COG1302	Protein conserved in bacteria
CGZ69_RS18900	COG2018	Roadblock/LC7 domain
CGZ69_RS19075	COG3547	Transposase (IS116 IS110 IS902 family)
CGZ69_RS19110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGZ69_RS19120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGZ69_RS19120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGZ69_RS19135	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS19170	COG0717	Belongs to the dCTP deaminase family
CGZ69_RS19200	COG0443	Heat shock 70 kDa protein
CGZ69_RS19205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGZ69_RS19210	COG0484	heat shock protein binding
CGZ69_RS19215	COG0789	Transcriptional regulator
CGZ69_RS19240	COG0542	response to heat
CGZ69_RS19270	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CGZ69_RS19285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGZ69_RS19290	COG0191	fructose-bisphosphate aldolase activity
CGZ69_RS19295	COG0477	Major facilitator Superfamily
CGZ69_RS19315	COG3844	kynureninase activity
CGZ69_RS19340	COG4585	Histidine kinase
CGZ69_RS19345	COG2197	response regulator
CGZ69_RS19350	COG4585	Histidine kinase
CGZ69_RS19355	COG2197	response regulator
CGZ69_RS19360	COG2124	cytochrome p450
CGZ69_RS19370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGZ69_RS19410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CGZ69_RS19425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CGZ69_RS19450	COG0693	protein deglycase activity
CGZ69_RS19455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGZ69_RS19475	COG1802	Transcriptional regulator
CGZ69_RS19480	COG0463	Glycosyl transferase, family 2
CGZ69_RS19500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CGZ69_RS19505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGZ69_RS19525	COG1595	DNA-templated transcription, initiation
CGZ69_RS19585	COG1408	metallophosphoesterase
CGZ69_RS19590	COG5650	phosphatidylinositol metabolic process
CGZ69_RS19600	COG1610	YqeY-like protein
CGZ69_RS19605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGZ69_RS19620	COG0003	Pfam Anion-transporting ATPase
CGZ69_RS19635	COG0251	oxidation-reduction process
CGZ69_RS19645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGZ69_RS19675	COG2267	carboxylic ester hydrolase activity
CGZ69_RS19685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CGZ69_RS19690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGZ69_RS19695	COG0659	secondary active sulfate transmembrane transporter activity
CGZ69_RS19755	COG1205	dead DEAH box helicase
CGZ69_RS19755	COG1111	helicase
CGZ69_RS19760	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS19770	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CGZ69_RS19780	COG2890	protein-(glutamine-N5) methyltransferase activity
CGZ69_RS19790	COG1754	DNA topoisomerase type I activity
CGZ69_RS19790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGZ69_RS19800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGZ69_RS19815	COG0477	Major facilitator Superfamily
CGZ69_RS19825	COG2018	Roadblock/LC7 domain
CGZ69_RS19855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGZ69_RS19855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGZ69_RS19875	COG1136	(ABC) transporter
CGZ69_RS19875	COG0577	efflux transmembrane transporter activity
CGZ69_RS19895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGZ69_RS19900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGZ69_RS19905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CGZ69_RS19910	COG0254	rRNA binding
CGZ69_RS19920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGZ69_RS19940	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS19945	COG2318	DinB family
CGZ69_RS19960	COG0076	glutamate decarboxylase activity
CGZ69_RS19965	COG0789	Transcriptional regulator
CGZ69_RS19970	COG0393	Putative heavy-metal-binding
CGZ69_RS19985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CGZ69_RS19990	COG2027	D-alanyl-D-alanine carboxypeptidase
CGZ69_RS20000	COG0037	tRNA processing
CGZ69_RS20015	COG0302	gtp cyclohydrolase
CGZ69_RS20020	COG0667	Aldo Keto reductase
CGZ69_RS20035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGZ69_RS20060	COG1125	glycine betaine transport
CGZ69_RS20060	COG0517	IMP dehydrogenase activity
CGZ69_RS20070	COG1174	glycine betaine transport
CGZ69_RS20085	COG0649	NAD binding
CGZ69_RS20100	COG2197	response regulator
CGZ69_RS20125	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGZ69_RS20130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CGZ69_RS20140	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CGZ69_RS20155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CGZ69_RS20190	COG2027	D-alanyl-D-alanine carboxypeptidase
CGZ69_RS20200	COG0739	heme binding
CGZ69_RS20210	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS20220	COG1595	DNA-templated transcription, initiation
CGZ69_RS20225	COG1194	a g-specific adenine glycosylase
CGZ69_RS20230	COG0671	phosphoesterase, PA-phosphatase related
CGZ69_RS20240	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CGZ69_RS20260	COG0248	Ppx GppA phosphatase
CGZ69_RS20265	COG1082	Xylose isomerase domain protein TIM barrel
CGZ69_RS20285	COG4991	sh3 domain protein
CGZ69_RS20295	COG1129	ABC transporter
CGZ69_RS20295	COG0842	Transport permease protein
CGZ69_RS20305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGZ69_RS20310	COG0180	Tryptophanyl-tRNA synthetase
CGZ69_RS20335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ69_RS20345	COG0123	including yeast histone deacetylase and acetoin utilization protein
CGZ69_RS20380	COG1595	DNA-templated transcription, initiation
CGZ69_RS20395	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGZ69_RS20400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGZ69_RS20405	COG0181	hydroxymethylbilane synthase activity
CGZ69_RS20410	COG1648	precorrin-2 dehydrogenase activity
CGZ69_RS20410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGZ69_RS20420	COG0113	porphobilinogen synthase activity
CGZ69_RS20425	COG1309	transcriptional regulator
CGZ69_RS20485	COG0018	arginyl-trna synthetase
CGZ69_RS20490	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CGZ69_RS20515	COG1690	Belongs to the RtcB family
CGZ69_RS20535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGZ69_RS20545	COG1846	Transcriptional regulator
CGZ69_RS20590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CGZ69_RS20595	COG0406	alpha-ribazole phosphatase activity
CGZ69_RS20610	COG0785	Cytochrome C biogenesis protein
CGZ69_RS20615	COG1333	cytochrome c biogenesis protein
CGZ69_RS20620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGZ69_RS20640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CGZ69_RS20665	COG0163	prenyltransferase activity
CGZ69_RS20675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CGZ69_RS20690	COG1301	dicarboxylic acid transport
CGZ69_RS20695	COG1309	transcriptional regulator
CGZ69_RS20705	COG1278	Cold shock
CGZ69_RS20715	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CGZ69_RS20725	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CGZ69_RS20745	COG2226	methyltransferase
CGZ69_RS20750	COG2066	Belongs to the glutaminase family
CGZ69_RS20795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20805	COG0649	NAD binding
CGZ69_RS20815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CGZ69_RS20820	COG1034	ATP synthesis coupled electron transport
CGZ69_RS20825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CGZ69_RS20830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20840	COG0713	ATP synthesis coupled electron transport
CGZ69_RS20845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGZ69_RS20855	COG1007	ATP synthesis coupled electron transport
CGZ69_RS20880	COG0142	geranyltranstransferase activity
CGZ69_RS20900	COG4935	Belongs to the peptidase S8 family
CGZ69_RS20900	COG2234	aminopeptidase activity
CGZ69_RS20935	COG1013	pyruvate-flavodoxin oxidoreductase activity
CGZ69_RS20940	COG0674	pyruvate-flavodoxin oxidoreductase activity
CGZ69_RS20940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CGZ69_RS20960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20970	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CGZ69_RS20980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGZ69_RS20985	COG0839	Belongs to the complex I subunit 6 family
CGZ69_RS20990	COG0713	ATP synthesis coupled electron transport
CGZ69_RS21005	COG1007	ATP synthesis coupled electron transport
CGZ69_RS21010	COG0501	Belongs to the peptidase M48B family
CGZ69_RS21015	COG3304	Inner membrane component domain
CGZ69_RS21035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGZ69_RS21040	COG1666	GTP binding
CGZ69_RS21095	COG0402	S-adenosylhomocysteine deaminase activity
CGZ69_RS21110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CGZ69_RS21115	COG2030	dehydratase
CGZ69_RS21130	COG0477	Major facilitator Superfamily
CGZ69_RS21135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CGZ69_RS21150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGZ69_RS21155	COG0436	Aminotransferase
CGZ69_RS21165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGZ69_RS21175	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGZ69_RS21185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGZ69_RS21190	COG0222	ribosome binding
CGZ69_RS21200	COG0085	RNA polymerase activity
CGZ69_RS21205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGZ69_RS21215	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGZ69_RS21220	COG0049	tRNA binding
CGZ69_RS21225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGZ69_RS21230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGZ69_RS21260	COG0051	transcription antitermination factor activity, RNA binding
CGZ69_RS21265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGZ69_RS21270	COG0088	Forms part of the polypeptide exit tunnel
CGZ69_RS21275	COG0089	rRNA binding
CGZ69_RS21280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGZ69_RS21285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGZ69_RS21290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGZ69_RS21295	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGZ69_RS21300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGZ69_RS21305	COG0255	Belongs to the universal ribosomal protein uL29 family
CGZ69_RS21310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGZ69_RS21315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGZ69_RS21320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGZ69_RS21325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGZ69_RS21330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGZ69_RS21340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGZ69_RS21345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGZ69_RS21350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CGZ69_RS21355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGZ69_RS21360	COG1841	ribosomal large subunit assembly
CGZ69_RS21365	COG0200	Binds to the 23S rRNA
CGZ69_RS21375	COG0563	adenylate kinase activity
CGZ69_RS21385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGZ69_RS21390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGZ69_RS21395	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGZ69_RS21400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGZ69_RS21405	COG0202	RNA polymerase activity
CGZ69_RS21410	COG0203	ribosomal protein L17
CGZ69_RS21415	COG0101	tRNA pseudouridine synthase activity
CGZ69_RS21425	COG0488	(ABC) transporter
CGZ69_RS21435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGZ69_RS21435	COG0515	serine threonine protein kinase
CGZ69_RS21440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGZ69_RS21445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CGZ69_RS21450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGZ69_RS21460	COG1072	(Pantothenic acid kinase))
CGZ69_RS21475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGZ69_RS21480	COG0736	holo-[acyl-carrier-protein] synthase activity
CGZ69_RS21490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGZ69_RS21500	COG0802	atpase or kinase
CGZ69_RS21525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGZ69_RS21540	COG4941	Belongs to the sigma-70 factor family
CGZ69_RS21560	COG0726	polysaccharide deacetylase
CGZ69_RS21580	COG4221	oxidoreductase activity
CGZ69_RS21585	COG2132	Multicopper oxidase
CGZ69_RS21595	COG0583	DNA-binding transcription factor activity
CGZ69_RS21610	COG1595	DNA-templated transcription, initiation
CGZ69_RS21620	COG0516	GMP reductase activity
CGZ69_RS21635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGZ69_RS21650	COG0515	serine threonine protein kinase
CGZ69_RS21655	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS21675	COG0519	Catalyzes the synthesis of GMP from XMP
CGZ69_RS21675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGZ69_RS21700	COG2197	response regulator
CGZ69_RS21740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS21760	COG0714	Associated with various cellular activities
CGZ69_RS21770	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CGZ69_RS21775	COG0045	succinate-CoA ligase (ADP-forming) activity
CGZ69_RS21805	COG0138	bifunctional purine biosynthesis protein purh
CGZ69_RS21815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGZ69_RS21825	COG0538	isocitrate dehydrogenase activity
CGZ69_RS21835	COG0039	L-malate dehydrogenase activity
CGZ69_RS21870	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS21880	COG0517	IMP dehydrogenase activity
CGZ69_RS21880	COG4175	Glycine betaine
CGZ69_RS21905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ69_RS21910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGZ69_RS21915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGZ69_RS21920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGZ69_RS21930	COG0180	Tryptophanyl-tRNA synthetase
CGZ69_RS21945	COG1686	Belongs to the peptidase S11 family
CGZ69_RS21955	COG1408	metallophosphoesterase
CGZ69_RS21960	COG1309	transcriptional regulator
CGZ69_RS22005	COG1053	succinate dehydrogenase
CGZ69_RS22015	COG2009	succinate dehydrogenase
CGZ69_RS22105	COG1733	regulation of RNA biosynthetic process
CGZ69_RS22110	COG0655	NAD(P)H dehydrogenase (quinone) activity
CGZ69_RS22120	COG1846	Transcriptional regulator
CGZ69_RS22180	COG1595	DNA-templated transcription, initiation
CGZ69_RS22195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS22195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS22210	COG1215	transferase activity, transferring glycosyl groups
CGZ69_RS22225	COG2089	acid synthase
CGZ69_RS22235	COG1473	amidohydrolase
CGZ69_RS22235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGZ69_RS22240	COG1744	ABC transporter substrate-binding protein PnrA-like
CGZ69_RS22245	COG3845	ABC transporter
CGZ69_RS22255	COG1079	Belongs to the binding-protein-dependent transport system permease family
CGZ69_RS22280	COG2814	Major facilitator Superfamily
CGZ69_RS22285	COG0583	DNA-binding transcription factor activity
CGZ69_RS22295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGZ69_RS22325	COG2205	protein histidine kinase activity
CGZ69_RS22330	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS22335	COG1595	DNA-templated transcription, initiation
CGZ69_RS22355	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS22370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGZ69_RS22400	COG4770	biotin carboxylase activity
CGZ69_RS22410	COG0424	maF-like protein
CGZ69_RS22420	COG1309	transcriptional regulator
CGZ69_RS22435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS22450	COG1024	Enoyl-CoA hydratase
CGZ69_RS22460	COG2986	histidine ammonia-lyase
CGZ69_RS22475	COG1376	ErfK ybiS ycfS ynhG family protein
CGZ69_RS22490	COG1064	alcohol dehydrogenase
CGZ69_RS22500	COG1396	sequence-specific DNA binding
CGZ69_RS22505	COG0740	serine-type endopeptidase activity
CGZ69_RS22510	COG0740	serine-type endopeptidase activity
CGZ69_RS22520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGZ69_RS22525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGZ69_RS22555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGZ69_RS22570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGZ69_RS22580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGZ69_RS22620	COG1331	Highly conserved protein containing a thioredoxin domain
CGZ69_RS22635	COG0463	Glycosyl transferase, family 2
CGZ69_RS22655	COG1309	transcriptional regulator
CGZ69_RS22665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CGZ69_RS22685	COG2890	protein-(glutamine-N5) methyltransferase activity
CGZ69_RS22740	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CGZ69_RS22760	COG1414	Transcriptional regulator
CGZ69_RS22765	COG0251	oxidation-reduction process
CGZ69_RS22770	COG2610	gluconate transmembrane transporter activity
CGZ69_RS22850	COG2885	chlorophyll binding
CGZ69_RS22885	COG0667	Aldo Keto reductase
CGZ69_RS22890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGZ69_RS22895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CGZ69_RS22915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ69_RS22920	COG0450	alkyl hydroperoxide reductase
CGZ69_RS22965	COG0114	fumarate hydratase activity
CGZ69_RS22975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CGZ69_RS22975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CGZ69_RS23000	COG0778	Nitroreductase
CGZ69_RS23005	COG1722	exodeoxyribonuclease VII activity
CGZ69_RS23010	COG1570	exodeoxyribonuclease VII activity
CGZ69_RS23015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGZ69_RS23030	COG0012	GTP binding
CGZ69_RS23075	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS23085	COG0601	transmembrane transport
CGZ69_RS23090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ69_RS23100	COG0006	proline dipeptidase activity
CGZ69_RS23105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS23125	COG3938	Belongs to the proline racemase family
CGZ69_RS23135	COG1802	Transcriptional regulator
CGZ69_RS23145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGZ69_RS23220	COG1053	succinate dehydrogenase
CGZ69_RS23240	COG1217	gtp-binding protein TYPA
CGZ69_RS23245	COG4166	transmembrane transport
CGZ69_RS23250	COG0601	transmembrane transport
CGZ69_RS23255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ69_RS23265	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS23285	COG0601	transmembrane transport
CGZ69_RS23290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ69_RS23300	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS23320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGZ69_RS23395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGZ69_RS23400	COG1611	Belongs to the LOG family
CGZ69_RS23405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGZ69_RS23415	COG0519	Catalyzes the synthesis of GMP from XMP
CGZ69_RS23420	COG1024	Enoyl-CoA hydratase
CGZ69_RS23435	COG1595	DNA-templated transcription, initiation
CGZ69_RS23445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGZ69_RS23450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGZ69_RS23470	COG2239	Acts as a magnesium transporter
CGZ69_RS23485	COG0598	Magnesium transport protein CorA
CGZ69_RS23510	COG2095	MarC family integral membrane protein
CGZ69_RS23520	COG1432	Conserved Protein
CGZ69_RS23525	COG2267	carboxylic ester hydrolase activity
CGZ69_RS23530	COG0513	Belongs to the DEAD box helicase family
CGZ69_RS23685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGZ69_RS23735	COG3480	Lon protease (S16) C-terminal proteolytic domain
CGZ69_RS23745	COG1615	UPF0182 protein
CGZ69_RS23770	COG0753	catalase activity
CGZ69_RS23780	COG0483	inositol monophosphate 1-phosphatase activity
CGZ69_RS23790	COG2076	Multidrug Resistance protein
CGZ69_RS23800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGZ69_RS23810	COG2135	peptidase activity
CGZ69_RS23820	COG1595	DNA-templated transcription, initiation
CGZ69_RS23825	COG5662	AntiSigma factor
CGZ69_RS23830	COG2199	diguanylate cyclase activity
CGZ69_RS23830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CGZ69_RS23845	COG0242	peptide deformylase activity
CGZ69_RS23855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGZ69_RS23880	COG2188	Transcriptional regulator
CGZ69_RS23890	COG1175	transmembrane transport
CGZ69_RS23895	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS23900	COG1472	Belongs to the glycosyl hydrolase 3 family
CGZ69_RS23920	COG1597	lipid kinase activity
CGZ69_RS23955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGZ69_RS23960	COG0142	geranyltranstransferase activity
CGZ69_RS24005	COG4106	trans-aconitate 2-methyltransferase activity
CGZ69_RS24010	COG1126	abc transporter atp-binding protein
CGZ69_RS24015	COG0765	amino acid transport
CGZ69_RS24035	COG3540	Alkaline phosphatase
CGZ69_RS24040	COG0604	alcohol dehydrogenase
CGZ69_RS24085	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGZ69_RS24085	COG0567	Dehydrogenase, E1 component
CGZ69_RS24090	COG2205	protein histidine kinase activity
CGZ69_RS24095	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS24115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CGZ69_RS24120	COG1357	PFAM Pentapeptide repeats (8 copies)
CGZ69_RS24210	COG0768	penicillin binding
CGZ69_RS24245	COG3285	dna ligase
CGZ69_RS24245	COG1793	dna ligase
CGZ69_RS24250	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGZ69_RS24260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ69_RS24270	COG1414	Transcriptional regulator
CGZ69_RS24275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ69_RS24305	COG1252	NADH dehydrogenase
CGZ69_RS24330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGZ69_RS24335	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CGZ69_RS24375	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS24450	COG1120	ATPase activity
CGZ69_RS24455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS24490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGZ69_RS24530	COG3321	synthase
CGZ69_RS24530	COG0604	alcohol dehydrogenase
CGZ69_RS24535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ69_RS24540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS24630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CGZ69_RS24670	COG2197	response regulator
CGZ69_RS24745	COG2188	Transcriptional regulator
CGZ69_RS24780	COG1674	ftsk spoiiie
CGZ69_RS24825	COG0582	viral genome integration into host DNA
CGZ69_RS24830	COG2815	serine threonine protein kinase
CGZ69_RS24830	COG0515	serine threonine protein kinase
CGZ69_RS24845	COG0018	arginyl-trna synthetase
CGZ69_RS24850	COG0019	diaminopimelate decarboxylase activity
CGZ69_RS24855	COG0460	homoserine dehydrogenase
CGZ69_RS24860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGZ69_RS24865	COG0083	homoserine kinase activity
CGZ69_RS24875	COG1316	TRANSCRIPTIONal
CGZ69_RS24880	COG0254	rRNA binding
CGZ69_RS24885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGZ69_RS24890	COG2890	protein-(glutamine-N5) methyltransferase activity
CGZ69_RS24900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGZ69_RS24905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGZ69_RS24925	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGZ69_RS24935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGZ69_RS24940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGZ69_RS24945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGZ69_RS24950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGZ69_RS24955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGZ69_RS24970	COG2197	response regulator
CGZ69_RS24975	COG3850	Histidine kinase
CGZ69_RS25000	COG1309	transcriptional regulator
CGZ69_RS25005	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS25020	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CGZ69_RS25075	COG0183	Belongs to the thiolase family
CGZ69_RS25130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS25130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS25170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGZ69_RS25175	COG0857	belongs to the CobB CobQ family
CGZ69_RS25175	COG0280	phosphate acetyltransferase
CGZ69_RS25180	COG0205	6-phosphofructokinase activity
CGZ69_RS25195	COG3833	ABC-type maltose transport systems, permease component
CGZ69_RS25200	COG1175	transmembrane transport
CGZ69_RS25205	COG4565	transcriptional regulatory protein
CGZ69_RS25210	COG3290	protein histidine kinase activity
CGZ69_RS25215	COG1301	dicarboxylic acid transport
CGZ69_RS25220	COG0667	Aldo Keto reductase
CGZ69_RS25230	COG1522	sequence-specific DNA binding
CGZ69_RS25240	COG3118	belongs to the thioredoxin family
CGZ69_RS25255	COG3973	AAA domain
CGZ69_RS25275	COG0366	Alpha amylase catalytic
CGZ69_RS25280	COG0366	Alpha amylase catalytic
CGZ69_RS25285	COG0058	SHG alpha-glucan phosphorylase activity
CGZ69_RS25310	COG2252	PERMEase
CGZ69_RS25315	COG4585	Histidine kinase
CGZ69_RS25335	COG1136	(ABC) transporter
CGZ69_RS25365	COG1376	ErfK ybiS ycfS ynhG family protein
CGZ69_RS25370	COG1376	ErfK ybiS ycfS ynhG family protein
CGZ69_RS25440	COG1760	l-serine dehydratase
CGZ69_RS25450	COG0788	formyltetrahydrofolate deformylase activity
CGZ69_RS25475	COG0588	phosphoglycerate mutase activity
CGZ69_RS25490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGZ69_RS25495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGZ69_RS25520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CGZ69_RS25525	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS25560	COG3629	intracellular signal transduction
CGZ69_RS25560	COG3903	Transcriptional regulator
CGZ69_RS25575	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS25580	COG1760	l-serine dehydratase
CGZ69_RS25585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGZ69_RS25590	COG0509	glycine decarboxylation via glycine cleavage system
CGZ69_RS25595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGZ69_RS25615	COG0747	negative chemotaxis
CGZ69_RS25620	COG0601	transmembrane transport
CGZ69_RS25625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ69_RS25630	COG0444	Belongs to the ABC transporter superfamily
CGZ69_RS25635	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS25640	COG2860	membrane
CGZ69_RS25655	COG2378	regulation of single-species biofilm formation
CGZ69_RS25690	COG0482	sulfurtransferase activity
CGZ69_RS25715	COG4221	oxidoreductase activity
CGZ69_RS25725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGZ69_RS25735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGZ69_RS25740	COG0154	amidase activity
CGZ69_RS25750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGZ69_RS25765	COG2409	Drug exporters of the RND superfamily
CGZ69_RS25770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS25790	COG2197	response regulator
CGZ69_RS25800	COG2133	pyrroloquinoline quinone binding
CGZ69_RS25805	COG0667	Aldo Keto reductase
CGZ69_RS25825	COG0440	acetolactate synthase activity
CGZ69_RS25830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGZ69_RS25845	COG3835	regulator
CGZ69_RS25850	COG0506	proline dehydrogenase activity
CGZ69_RS25855	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS25875	COG1695	Transcriptional regulator
CGZ69_RS25885	COG0473	3-isopropylmalate dehydrogenase activity
CGZ69_RS25890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGZ69_RS25900	COG0832	Belongs to the urease beta subunit family
CGZ69_RS25900	COG0831	urea catabolic process
CGZ69_RS25905	COG0804	urea catabolic process
CGZ69_RS25910	COG2957	Belongs to the agmatine deiminase family
CGZ69_RS25915	COG1309	transcriptional regulator
CGZ69_RS25920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGZ69_RS25935	COG2353	YceI-like domain
CGZ69_RS25950	COG1470	cell adhesion involved in biofilm formation
CGZ69_RS25950	COG0366	Alpha amylase catalytic
CGZ69_RS25955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS25970	COG0789	Transcriptional regulator
CGZ69_RS25985	COG2018	Roadblock/LC7 domain
CGZ69_RS26005	COG2018	Roadblock/LC7 domain
CGZ69_RS26010	COG5002	protein histidine kinase activity
CGZ69_RS26020	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGZ69_RS26025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGZ69_RS26035	COG1011	Hydrolase
CGZ69_RS26080	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS26085	COG1414	Transcriptional regulator
CGZ69_RS26090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGZ69_RS26095	COG0066	3-isopropylmalate dehydratase activity
CGZ69_RS26105	COG0776	regulation of translation
CGZ69_RS26115	COG1920	GTP binding
CGZ69_RS26125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGZ69_RS26130	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGZ69_RS26150	COG0351	phosphomethylpyrimidine kinase
CGZ69_RS26155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGZ69_RS26160	COG1461	Dihydroxyacetone kinase
CGZ69_RS26170	COG0326	Molecular chaperone. Has ATPase activity
CGZ69_RS26180	COG0742	ribosomal rna small subunit methyltransferase
CGZ69_RS26185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGZ69_RS26200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CGZ69_RS26205	COG0571	ribonuclease III activity
CGZ69_RS26210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGZ69_RS26215	COG2340	Cysteine-rich secretory protein family
CGZ69_RS26220	COG1254	Belongs to the acylphosphatase family
CGZ69_RS26235	COG1196	nuclear chromosome segregation
CGZ69_RS26240	COG0477	Major facilitator Superfamily
CGZ69_RS26275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CGZ69_RS26290	COG0442	prolyl-tRNA aminoacylation
CGZ69_RS26300	COG0228	four-way junction DNA binding
CGZ69_RS26305	COG1837	Belongs to the UPF0109 family
CGZ69_RS26310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGZ69_RS26315	COG0336	Belongs to the RNA methyltransferase TrmD family
CGZ69_RS26320	COG0335	large ribosomal subunit rRNA binding
CGZ69_RS26325	COG0681	Belongs to the peptidase S26 family
CGZ69_RS26335	COG0681	Belongs to the peptidase S26 family
CGZ69_RS26340	COG0681	Belongs to the peptidase S26 family
CGZ69_RS26355	COG0792	nuclease activity
CGZ69_RS26385	COG0789	Transcriptional regulator
CGZ69_RS26435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGZ69_RS26440	COG0494	nUDIX hydrolase
CGZ69_RS26485	COG1191	sigma factor activity
CGZ69_RS26500	COG0052	Belongs to the universal ribosomal protein uS2 family
CGZ69_RS26505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGZ69_RS26510	COG0528	UMP kinase activity
CGZ69_RS26515	COG0233	cytoplasmic translational termination
CGZ69_RS26520	COG0575	Belongs to the CDS family
CGZ69_RS26535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CGZ69_RS26550	COG3842	ATPase activity
CGZ69_RS26565	COG1136	(ABC) transporter
CGZ69_RS26570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGZ69_RS26580	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS26605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGZ69_RS26620	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS26625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CGZ69_RS26630	COG3842	ATPase activity
CGZ69_RS26635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CGZ69_RS26640	COG1177	transmembrane transport
CGZ69_RS26645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS26680	COG0697	spore germination
CGZ69_RS26720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CGZ69_RS26725	COG0750	zinc metalloprotease
CGZ69_RS26730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGZ69_RS26740	COG1247	-acetyltransferase
CGZ69_RS26745	COG0442	prolyl-tRNA aminoacylation
CGZ69_RS26765	COG0779	Required for maturation of 30S ribosomal subunits
CGZ69_RS26780	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGZ69_RS26790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGZ69_RS26795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGZ69_RS26820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGZ69_RS26825	COG0601	transmembrane transport
CGZ69_RS26835	COG0455	bacterial-type flagellum organization
CGZ69_RS26855	COG3266	domain, Protein
CGZ69_RS26860	COG1404	Belongs to the peptidase S8 family
CGZ69_RS26875	COG1404	Belongs to the peptidase S8 family
CGZ69_RS26895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGZ69_RS26895	COG0515	serine threonine protein kinase
CGZ69_RS26925	COG1674	ftsk spoiiie
CGZ69_RS26935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGZ69_RS26945	COG0612	Peptidase, M16
CGZ69_RS26950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CGZ69_RS26970	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CGZ69_RS26975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGZ69_RS26980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGZ69_RS27010	COG2208	phosphoserine phosphatase activity
CGZ69_RS27010	COG2770	Histidine kinase
CGZ69_RS27015	COG3850	Histidine kinase
CGZ69_RS27015	COG3437	response regulator, receiver
CGZ69_RS27015	COG2205	protein histidine kinase activity
CGZ69_RS27015	COG4999	Histidine kinase
CGZ69_RS27035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGZ69_RS27045	COG1058	Belongs to the CinA family
CGZ69_RS27045	COG1546	Belongs to the CinA family
CGZ69_RS27050	COG1396	sequence-specific DNA binding
CGZ69_RS27055	COG0783	Belongs to the Dps family
CGZ69_RS27065	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS27070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGZ69_RS27075	COG1201	RNA secondary structure unwinding
CGZ69_RS27110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGZ69_RS27125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGZ69_RS27130	COG0765	amino acid transport
CGZ69_RS27135	COG0765	amino acid transport
CGZ69_RS27140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ69_RS27145	COG1126	abc transporter atp-binding protein
CGZ69_RS27150	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS27155	COG2205	protein histidine kinase activity
CGZ69_RS27165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGZ69_RS27185	COG3321	synthase
CGZ69_RS27185	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS27185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS27185	COG0300	oxidoreductase activity
CGZ69_RS27185	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS27205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGZ69_RS27220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ69_RS27225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS27230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS27270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ69_RS27275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGZ69_RS27280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGZ69_RS27285	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS27310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS27325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS27330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS27345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGZ69_RS27355	COG2409	Drug exporters of the RND superfamily
CGZ69_RS27365	COG0142	geranyltranstransferase activity
CGZ69_RS27370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS27380	COG3629	intracellular signal transduction
CGZ69_RS27380	COG3903	Transcriptional regulator
CGZ69_RS27390	COG3903	Transcriptional regulator
CGZ69_RS27390	COG3629	intracellular signal transduction
CGZ69_RS27405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGZ69_RS27425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGZ69_RS27435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGZ69_RS27440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGZ69_RS27450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGZ69_RS27495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGZ69_RS27500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGZ69_RS27520	COG0588	phosphoglycerate mutase activity
CGZ69_RS27540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGZ69_RS27575	COG1802	Transcriptional regulator
CGZ69_RS27580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGZ69_RS27595	COG0187	DNA topoisomerase II activity
CGZ69_RS27600	COG4585	Histidine kinase
CGZ69_RS27605	COG2197	response regulator
CGZ69_RS27615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS27625	COG3290	protein histidine kinase activity
CGZ69_RS27640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGZ69_RS27645	COG0612	Peptidase, M16
CGZ69_RS27660	COG1802	Transcriptional regulator
CGZ69_RS27665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGZ69_RS27670	COG0045	succinate-CoA ligase (ADP-forming) activity
CGZ69_RS27670	COG1042	CoA-binding domain protein
CGZ69_RS27670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS27670	COG0045	succinate-CoA ligase (ADP-forming) activity
CGZ69_RS27670	COG1042	CoA-binding domain protein
CGZ69_RS27670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS27685	COG1435	thymidine kinase activity
CGZ69_RS27725	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS27745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CGZ69_RS27755	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS27760	COG2205	protein histidine kinase activity
CGZ69_RS27785	COG0756	dUTP diphosphatase activity
CGZ69_RS27795	COG1136	(ABC) transporter
CGZ69_RS27795	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGZ69_RS27830	COG0569	domain protein
CGZ69_RS27835	COG0531	amino acid
CGZ69_RS27840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGZ69_RS27850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGZ69_RS27855	COG0531	amino acid
CGZ69_RS27890	COG0583	DNA-binding transcription factor activity
CGZ69_RS27895	COG0747	negative chemotaxis
CGZ69_RS27900	COG0601	transmembrane transport
CGZ69_RS27910	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS27915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGZ69_RS27920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGZ69_RS27955	COG1278	Cold shock
CGZ69_RS27980	COG1201	RNA secondary structure unwinding
CGZ69_RS28085	COG1401	restriction endodeoxyribonuclease activity
CGZ69_RS28120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGZ69_RS28125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CGZ69_RS28155	COG0604	alcohol dehydrogenase
CGZ69_RS28155	COG3321	synthase
CGZ69_RS28190	COG0604	alcohol dehydrogenase
CGZ69_RS28190	COG3321	synthase
CGZ69_RS28200	COG0604	alcohol dehydrogenase
CGZ69_RS28200	COG3321	synthase
CGZ69_RS28205	COG0477	Major facilitator Superfamily
CGZ69_RS28230	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS28355	COG2268	Band 7 protein
CGZ69_RS28360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGZ69_RS28375	COG1335	isochorismatase
CGZ69_RS28390	COG1388	LysM domain
CGZ69_RS28390	COG3942	CHAP domain
CGZ69_RS28430	COG2226	methyltransferase
CGZ69_RS28445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGZ69_RS28450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGZ69_RS28475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGZ69_RS28485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGZ69_RS28490	COG2192	nodulation
CGZ69_RS28500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CGZ69_RS28505	COG0859	PFAM glycosyl transferase family 9
CGZ69_RS28515	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS28520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CGZ69_RS28525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGZ69_RS28525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGZ69_RS28530	COG0859	PFAM glycosyl transferase family 9
CGZ69_RS28540	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS28555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGZ69_RS28560	COG1609	Transcriptional regulator
CGZ69_RS28565	COG2182	Extracellular solute-binding protein
CGZ69_RS28570	COG1175	transmembrane transport
CGZ69_RS28575	COG3833	ABC-type maltose transport systems, permease component
CGZ69_RS28580	COG0366	Alpha amylase catalytic
CGZ69_RS28600	COG1799	cell septum assembly
CGZ69_RS28625	COG2040	homocysteine
CGZ69_RS28635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CGZ69_RS28695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGZ69_RS28705	COG1024	Enoyl-CoA hydratase
CGZ69_RS28780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGZ69_RS28785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CGZ69_RS28815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CGZ69_RS28820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS28850	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS28895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGZ69_RS28920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CGZ69_RS28930	COG1653	transport
CGZ69_RS28935	COG1175	transmembrane transport
CGZ69_RS28940	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS28945	COG1940	carbohydrate kinase activity
CGZ69_RS28950	COG4213	ABC transporter substrate-binding protein
CGZ69_RS28960	COG4214	carbohydrate transport
CGZ69_RS28965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGZ69_RS28970	COG0531	amino acid
CGZ69_RS28980	COG1316	TRANSCRIPTIONal
CGZ69_RS28985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGZ69_RS29020	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS29020	COG1024	Enoyl-CoA hydratase
CGZ69_RS29025	COG0183	Belongs to the thiolase family
CGZ69_RS29030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CGZ69_RS29045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CGZ69_RS29050	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGZ69_RS29060	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CGZ69_RS29065	COG3253	May function as heme-dependent peroxidase
CGZ69_RS29080	COG3220	belongs to the UPF0276 family
CGZ69_RS29125	COG0604	alcohol dehydrogenase
CGZ69_RS29185	COG1136	(ABC) transporter
CGZ69_RS29230	COG1136	(ABC) transporter
CGZ69_RS29240	COG1653	transport
CGZ69_RS29245	COG0366	Alpha amylase catalytic
CGZ69_RS29255	COG1175	transmembrane transport
CGZ69_RS29260	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS29270	COG1846	Transcriptional regulator
CGZ69_RS29275	COG1764	response to oxidative stress
CGZ69_RS29305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGZ69_RS29310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGZ69_RS29320	COG2197	response regulator
CGZ69_RS29325	COG4585	Histidine kinase
CGZ69_RS29330	COG1131	(ABC) transporter
CGZ69_RS29350	COG1073	alpha beta
CGZ69_RS29485	COG0583	DNA-binding transcription factor activity
CGZ69_RS29540	COG1175	transmembrane transport
CGZ69_RS29555	COG2409	Drug exporters of the RND superfamily
CGZ69_RS29570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGZ69_RS29585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGZ69_RS29590	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CGZ69_RS29610	COG0529	Catalyzes the synthesis of activated sulfate
CGZ69_RS29615	COG0175	sulfate reduction
CGZ69_RS29625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGZ69_RS29640	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS29655	COG2130	NADP-dependent
CGZ69_RS29670	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS29675	COG5002	protein histidine kinase activity
CGZ69_RS29705	COG1796	DNA polymerase
CGZ69_RS29705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CGZ69_RS29710	COG1162	GTPase activity
CGZ69_RS29730	COG0028	Belongs to the TPP enzyme family
CGZ69_RS29750	COG1802	Transcriptional regulator
CGZ69_RS29805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGZ69_RS29810	COG2252	PERMEase
CGZ69_RS29820	COG3585	molybdate ion transport
CGZ69_RS29880	COG2326	polyphosphate kinase activity
CGZ69_RS29930	COG3960	tartronate-semialdehyde synthase activity
CGZ69_RS29940	COG0753	catalase activity
CGZ69_RS29945	COG2084	Dehydrogenase
CGZ69_RS29950	COG3622	Belongs to the hyi family
CGZ69_RS30000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CGZ69_RS30015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGZ69_RS30065	COG2233	PERMEase
CGZ69_RS30115	COG2249	NAD(P)H dehydrogenase (quinone) activity
CGZ69_RS30125	COG2272	Belongs to the type-B carboxylesterase lipase family
CGZ69_RS30130	COG0384	phenazine biosynthesis protein PhzF
CGZ69_RS30135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGZ69_RS30160	COG0668	transmembrane transport
CGZ69_RS30165	COG0745	RESPONSE REGULATOR receiver
CGZ69_RS30170	COG2205	protein histidine kinase activity
CGZ69_RS30185	COG2340	Cysteine-rich secretory protein family
CGZ69_RS30195	COG3629	intracellular signal transduction
CGZ69_RS30195	COG3903	Transcriptional regulator
CGZ69_RS30235	COG0154	amidase activity
CGZ69_RS30240	COG1733	regulation of RNA biosynthetic process
CGZ69_RS30355	COG2267	carboxylic ester hydrolase activity
CGZ69_RS30370	COG1309	transcriptional regulator
CGZ69_RS30385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CGZ69_RS30425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGZ69_RS30430	COG4266	Belongs to the allantoicase family
CGZ69_RS30435	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS30465	COG0673	inositol 2-dehydrogenase activity
CGZ69_RS30470	COG2188	Transcriptional regulator
CGZ69_RS30475	COG1879	ABC-type sugar transport system periplasmic component
CGZ69_RS30495	COG1940	carbohydrate kinase activity
CGZ69_RS30525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ69_RS30545	COG1126	abc transporter atp-binding protein
CGZ69_RS30560	COG0405	Gamma-glutamyltransferase
CGZ69_RS30595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGZ69_RS30610	COG1953	Uracil, thiamine, allantoin
CGZ69_RS30650	COG1846	Transcriptional regulator
CGZ69_RS30670	COG0483	inositol monophosphate 1-phosphatase activity
CGZ69_RS30700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGZ69_RS30720	COG0494	nUDIX hydrolase
CGZ69_RS30725	COG1929	Belongs to the glycerate kinase type-1 family
CGZ69_RS30730	COG1621	beta-fructofuranosidase activity
CGZ69_RS30735	COG1621	beta-fructofuranosidase activity
CGZ69_RS30740	COG1653	transport
CGZ69_RS30750	COG4209	transmembrane transport
CGZ69_RS30755	COG1609	Transcriptional regulator
CGZ69_RS30770	COG0559	Belongs to the binding-protein-dependent transport system permease family
CGZ69_RS30775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGZ69_RS30800	COG0688	phosphatidylethanolamine metabolic process
CGZ69_RS30820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS30820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGZ69_RS30825	COG0604	alcohol dehydrogenase
CGZ69_RS30835	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS30855	COG2814	Major facilitator Superfamily
CGZ69_RS30880	COG1834	amidinotransferase
CGZ69_RS30885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGZ69_RS30890	COG2362	D-Aminopeptidase
CGZ69_RS30895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGZ69_RS30900	COG0823	Involved in the tonB-independent uptake of proteins
CGZ69_RS30900	COG4946	Tricorn protease homolog
CGZ69_RS30900	COG1506	peptidase
CGZ69_RS30905	COG1619	proteins homologs of microcin C7 resistance protein MccF
CGZ69_RS30915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGZ69_RS30930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGZ69_RS30945	COG2226	methyltransferase
CGZ69_RS30995	COG1064	alcohol dehydrogenase
CGZ69_RS31020	COG1793	dna ligase
CGZ69_RS31030	COG2154	pterin-4-alpha-carbinolamine dehydratase
CGZ69_RS31065	COG0656	L-ascorbic acid biosynthetic process
CGZ69_RS31130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGZ69_RS31150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ69_RS31155	COG1051	belongs to the nudix hydrolase family
CGZ69_RS31175	COG1129	ABC transporter
CGZ69_RS31180	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGZ69_RS31200	COG3291	Pkd domain containing protein
CGZ69_RS31210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CGZ69_RS31275	COG0443	Heat shock 70 kDa protein
CGZ69_RS31285	COG0515	serine threonine protein kinase
CGZ69_RS31295	COG1132	(ABC) transporter
CGZ69_RS31305	COG2197	response regulator
CGZ69_RS31315	COG0583	DNA-binding transcription factor activity
CGZ69_RS31340	COG1819	glycosyl
CGZ69_RS31360	COG0604	alcohol dehydrogenase
CGZ69_RS31365	COG1476	TRANSCRIPTIONal
CGZ69_RS31465	COG0702	epimerase
CGZ69_RS31470	COG1733	regulation of RNA biosynthetic process
CGZ69_RS31495	COG0789	Transcriptional regulator
CGZ69_RS31505	COG0583	DNA-binding transcription factor activity
CGZ69_RS31515	COG2855	membrane
CGZ69_RS31535	COG1070	Carbohydrate kinase
CGZ69_RS31550	COG0583	DNA-binding transcription factor activity
CGZ69_RS31555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGZ69_RS31560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CGZ69_RS31660	COG0431	NADPH-dependent FMN reductase
CGZ69_RS31690	COG1486	melibiose metabolic process
CGZ69_RS31695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGZ69_RS31695	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CGZ69_RS31700	COG3012	SEC-C Motif Domain Protein
CGZ69_RS31715	COG1793	dna ligase
CGZ69_RS31735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGZ69_RS31740	COG1215	transferase activity, transferring glycosyl groups
CGZ69_RS31745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGZ69_RS31800	COG0488	(ABC) transporter
CGZ69_RS31850	COG1131	(ABC) transporter
CGZ69_RS31870	COG0442	prolyl-tRNA aminoacylation
CGZ69_RS31875	COG2318	DinB family
CGZ69_RS31890	COG1515	deoxyribonuclease V activity
CGZ69_RS31900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGZ69_RS31905	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS31910	COG0183	Belongs to the thiolase family
CGZ69_RS31915	COG1024	Enoyl-CoA hydratase
CGZ69_RS31915	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS31925	COG0789	Transcriptional regulator
CGZ69_RS31975	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS32000	COG3226	Transcriptional regulator
CGZ69_RS32005	COG0110	maltose O-acetyltransferase activity
CGZ69_RS32025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGZ69_RS32050	COG0488	(ABC) transporter
CGZ69_RS32055	COG2183	response to ionizing radiation
CGZ69_RS32065	COG4977	sequence-specific DNA binding
CGZ69_RS32075	COG1024	Enoyl-CoA hydratase
CGZ69_RS32090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGZ69_RS32120	COG0371	Dehydrogenase
CGZ69_RS32140	COG1134	teichoic acid transport
CGZ69_RS32140	COG1388	LysM domain
CGZ69_RS32145	COG1562	ergosterol biosynthetic process
CGZ69_RS32155	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CGZ69_RS32165	COG1657	PFAM Prenyltransferase squalene oxidase
CGZ69_RS32190	COG2365	Tyrosine phosphatase family
CGZ69_RS32205	COG2755	lipolytic protein G-D-S-L family
CGZ69_RS32215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGZ69_RS32245	COG1309	transcriptional regulator
CGZ69_RS32250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGZ69_RS32290	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS32310	COG3958	Transketolase
CGZ69_RS32315	COG3959	Transketolase, thiamine diphosphate binding domain
CGZ69_RS32360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGZ69_RS32375	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS32380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGZ69_RS32395	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS32430	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS32450	COG0297	glycogen (starch) synthase activity
CGZ69_RS32450	COG0438	transferase activity, transferring glycosyl groups
CGZ69_RS32460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGZ69_RS32465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGZ69_RS32470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGZ69_RS32500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGZ69_RS32535	COG0302	gtp cyclohydrolase
CGZ69_RS32555	COG1595	DNA-templated transcription, initiation
CGZ69_RS32580	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS32595	COG1607	acyl-coa hydrolase
CGZ69_RS32600	COG2072	flavoprotein involved in K transport
CGZ69_RS32605	COG0657	acetylesterase activity
CGZ69_RS32620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGZ69_RS32625	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS32635	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS32655	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CGZ69_RS32655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGZ69_RS32665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS32690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGZ69_RS32700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGZ69_RS32705	COG1349	DNA-binding transcription factor activity
CGZ69_RS32720	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS32740	COG1652	LysM domain
CGZ69_RS32795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGZ69_RS32820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS32825	COG3275	phosphorelay sensor kinase activity
CGZ69_RS32875	COG2267	carboxylic ester hydrolase activity
CGZ69_RS32895	COG0583	DNA-binding transcription factor activity
CGZ69_RS32905	COG1053	succinate dehydrogenase
CGZ69_RS32910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGZ69_RS32920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGZ69_RS32940	COG2182	Extracellular solute-binding protein
CGZ69_RS32955	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CGZ69_RS32960	COG0121	glutamine amidotransferase
CGZ69_RS32965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGZ69_RS32990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGZ69_RS33140	COG2318	DinB family
CGZ69_RS33155	COG1755	Isoprenylcysteine carboxyl methyltransferase
CGZ69_RS33175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS33210	COG1595	DNA-templated transcription, initiation
CGZ69_RS33230	COG3540	Alkaline phosphatase
CGZ69_RS33255	COG1309	transcriptional regulator
CGZ69_RS33275	COG0673	inositol 2-dehydrogenase activity
CGZ69_RS33285	COG1349	DNA-binding transcription factor activity
CGZ69_RS33290	COG2182	Extracellular solute-binding protein
CGZ69_RS33300	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS33305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGZ69_RS33335	COG1063	alcohol dehydrogenase
CGZ69_RS33355	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS33370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGZ69_RS33385	COG1609	Transcriptional regulator
CGZ69_RS33425	COG4989	oxidoreductase activity
CGZ69_RS33475	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS33480	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS33505	COG2203	Gaf domain
CGZ69_RS33505	COG2199	diguanylate cyclase activity
CGZ69_RS33515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CGZ69_RS33520	COG0644	oxidoreductase
CGZ69_RS33530	COG2018	Roadblock/LC7 domain
CGZ69_RS33550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGZ69_RS33625	COG0477	Major facilitator Superfamily
CGZ69_RS33645	COG1233	COG1233 Phytoene dehydrogenase and related
CGZ69_RS33670	COG2018	Roadblock/LC7 domain
CGZ69_RS33680	COG1063	alcohol dehydrogenase
CGZ69_RS33685	COG0156	8-amino-7-oxononanoate synthase activity
CGZ69_RS33690	COG0583	DNA-binding transcription factor activity
CGZ69_RS33695	COG2826	transposase and inactivated derivatives, IS30 family
CGZ69_RS33735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGZ69_RS33735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGZ69_RS33745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGZ69_RS33750	COG0765	amino acid transport
CGZ69_RS33780	COG0592	DNA-directed DNA polymerase activity
CGZ69_RS33850	COG1982	Orn Lys Arg decarboxylase major
CGZ69_RS33860	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS33870	COG2207	Transcriptional regulator
CGZ69_RS33885	COG0277	FAD linked oxidase domain protein
CGZ69_RS33920	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CGZ69_RS33955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGZ69_RS33960	COG4106	trans-aconitate 2-methyltransferase activity
CGZ69_RS33980	COG0328	RNA-DNA hybrid ribonuclease activity
CGZ69_RS34030	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS34045	COG1024	Enoyl-CoA hydratase
CGZ69_RS34050	COG1960	acyl-CoA dehydrogenase activity
CGZ69_RS34055	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS34060	COG0183	Belongs to the thiolase family
CGZ69_RS34085	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS34120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGZ69_RS34140	COG0714	Associated with various cellular activities
CGZ69_RS34175	COG1366	Belongs to the anti-sigma-factor antagonist family
CGZ69_RS34175	COG2172	sigma factor antagonist activity
CGZ69_RS34175	COG2208	phosphoserine phosphatase activity
CGZ69_RS34180	COG3842	ATPase activity
CGZ69_RS34185	COG3842	ATPase activity
CGZ69_RS34190	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS34205	COG1064	alcohol dehydrogenase
CGZ69_RS34225	COG0596	Alpha beta hydrolase
CGZ69_RS34230	COG0183	Belongs to the thiolase family
CGZ69_RS34235	COG1011	Hydrolase
CGZ69_RS34240	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS34250	COG1309	transcriptional regulator
CGZ69_RS34260	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS34265	COG1024	Enoyl-CoA hydratase
CGZ69_RS34290	COG0318	PFAM AMP-dependent synthetase and ligase
CGZ69_RS34295	COG1946	Acyl-CoA thioesterase
CGZ69_RS34300	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGZ69_RS34300	COG1024	Enoyl-CoA hydratase
CGZ69_RS34305	COG2130	NADP-dependent
CGZ69_RS34310	COG1012	belongs to the aldehyde dehydrogenase family
CGZ69_RS34325	COG2814	Major facilitator Superfamily
CGZ69_RS34415	COG0659	secondary active sulfate transmembrane transporter activity
CGZ69_RS34430	COG0484	heat shock protein binding
CGZ69_RS34435	COG0443	Heat shock 70 kDa protein
CGZ69_RS34440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGZ69_RS34445	COG0513	Belongs to the DEAD box helicase family
CGZ69_RS34465	COG1295	ribonuclease BN
CGZ69_RS34485	COG1278	Cold shock
CGZ69_RS34510	COG1609	Transcriptional regulator
CGZ69_RS34520	COG0601	transmembrane transport
CGZ69_RS34530	COG0444	Belongs to the ABC transporter superfamily
CGZ69_RS34535	COG4608	Belongs to the ABC transporter superfamily
CGZ69_RS34555	COG1940	carbohydrate kinase activity
CGZ69_RS34555	COG1846	Transcriptional regulator
CGZ69_RS34560	COG0366	Alpha amylase catalytic
CGZ69_RS34575	COG0395	ABC-type sugar transport system, permease component
CGZ69_RS34665	COG3387	PFAM Glycoside hydrolase 15-related
CGZ69_RS34685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGZ69_RS34690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGZ69_RS34695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGZ69_RS34710	COG1834	amidinotransferase
CGZ69_RS34720	COG0765	amino acid transport
CGZ69_RS34725	COG1126	abc transporter atp-binding protein
CGZ69_RS34760	COG4948	Mandelate Racemase Muconate Lactonizing
CGZ69_RS34775	COG0405	Gamma-glutamyltransferase
CGZ69_RS34800	COG3118	belongs to the thioredoxin family
CGZ69_RS34810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGZ69_RS34820	COG2814	Major facilitator Superfamily
CGZ69_RS34840	COG4336	lyase activity
CGZ69_RS34845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGZ69_RS34850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CGZ69_RS34855	COG1984	allophanate hydrolase subunit 2
CGZ69_RS34860	COG2814	Major facilitator Superfamily
CGZ69_RS34875	COG3903	Transcriptional regulator
CGZ69_RS34875	COG3629	intracellular signal transduction
CGZ69_RS34890	COG0577	efflux transmembrane transporter activity
CGZ69_RS34890	COG1136	(ABC) transporter
CGZ69_RS34900	COG1653	transport
CGZ69_RS34920	COG1309	transcriptional regulator
CGZ69_RS34945	COG0531	amino acid
CGZ69_RS34990	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS34995	COG2135	peptidase activity
CGZ69_RS35065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGZ69_RS35200	COG1028	Short-chain dehydrogenase reductase Sdr
CGZ69_RS35240	COG1309	transcriptional regulator
CGZ69_RS35255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGZ69_RS35285	COG0583	DNA-binding transcription factor activity
CGZ69_RS35305	COG1024	Enoyl-CoA hydratase
CGZ69_RS35305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGZ69_RS35315	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CGZ69_RS35345	COG0375	protein maturation
CGZ69_RS35355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CGZ69_RS35360	COG0298	carbon dioxide binding
CGZ69_RS35365	COG0409	Hydrogenase expression formation protein
CGZ69_RS35435	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGZ69_RS35500	COG2319	Wd-40 repeat
CGZ69_RS35500	COG4249	Peptidase C14 caspase catalytic subunit p20
CGZ69_RS35550	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CGZ69_RS35645	COG2197	response regulator
CGZ69_RS35660	COG3263	regulation of cellular component size
CGZ69_RS35775	COG0789	Transcriptional regulator
CGZ69_RS35835	COG0402	S-adenosylhomocysteine deaminase activity
CGZ69_RS35850	COG2226	methyltransferase
CGZ69_RS35850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGZ69_RS35850	COG0596	Alpha beta hydrolase
CGZ69_RS35855	COG0473	3-isopropylmalate dehydrogenase activity
CGZ69_RS35855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGZ69_RS35865	COG0583	DNA-binding transcription factor activity
CGZ69_RS35920	COG0431	NADPH-dependent FMN reductase
CGZ69_RS35975	COG0601	transmembrane transport
CGZ69_RS35995	COG4948	Mandelate Racemase Muconate Lactonizing
CGZ69_RS36000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CGZ69_RS36010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGZ69_RS36040	COG0494	nUDIX hydrolase
CGZ69_RS36110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CGZ69_RS36120	COG0701	Predicted permease
CGZ69_RS36180	COG3210	domain, Protein