locus-tag	class	description
CP981_RS00060	COG0210	DNA helicase
CP981_RS00140	COG2197	response regulator
CP981_RS00145	COG4585	Histidine kinase
CP981_RS00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS00210	COG0454	-acetyltransferase
CP981_RS00220	COG0405	Gamma-glutamyltransferase
CP981_RS00225	COG5504	Zn-dependent protease
CP981_RS00235	COG2364	Membrane
CP981_RS00255	COG2226	methyltransferase
CP981_RS00260	COG0529	Catalyzes the synthesis of activated sulfate
CP981_RS00265	COG0667	Aldo Keto reductase
CP981_RS00270	COG1132	(ABC) transporter
CP981_RS00275	COG1132	(ABC) transporter
CP981_RS00280	COG3104	oligopeptide transport
CP981_RS00285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP981_RS00285	COG0512	Glutamine amidotransferase of anthranilate synthase
CP981_RS00300	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS00325	COG0438	transferase activity, transferring glycosyl groups
CP981_RS00325	COG1216	Glycosyl transferase, family 2
CP981_RS00330	COG0500	methyltransferase
CP981_RS00370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP981_RS00375	COG0800	Aldolase
CP981_RS00380	COG2226	methyltransferase
CP981_RS00420	COG4941	Belongs to the sigma-70 factor family
CP981_RS00440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP981_RS00445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP981_RS00450	COG0601	transmembrane transport
CP981_RS00485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP981_RS00510	COG0009	L-threonylcarbamoyladenylate synthase
CP981_RS00535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP981_RS00555	COG3647	Membrane
CP981_RS00595	COG2340	Cysteine-rich secretory protein family
CP981_RS00605	COG0577	efflux transmembrane transporter activity
CP981_RS00605	COG1136	(ABC) transporter
CP981_RS00615	COG1653	transport
CP981_RS00620	COG0366	Alpha amylase catalytic
CP981_RS00625	COG1653	transport
CP981_RS00630	COG1175	transmembrane transport
CP981_RS00635	COG0395	ABC-type sugar transport system, permease component
CP981_RS00650	COG1349	DNA-binding transcription factor activity
CP981_RS00655	COG1063	alcohol dehydrogenase
CP981_RS00660	COG2814	Major facilitator Superfamily
CP981_RS00685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP981_RS00690	COG2226	methyltransferase
CP981_RS00730	COG1271	oxidase subunit
CP981_RS00745	COG0300	oxidoreductase activity
CP981_RS00760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP981_RS00765	COG1113	amino acid transport
CP981_RS00780	COG2130	NADP-dependent
CP981_RS00805	COG0402	S-adenosylhomocysteine deaminase activity
CP981_RS00835	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP981_RS00910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP981_RS00930	COG3387	PFAM Glycoside hydrolase 15-related
CP981_RS00965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP981_RS00995	COG0181	hydroxymethylbilane synthase activity
CP981_RS01025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP981_RS01045	COG1794	racemase activity, acting on amino acids and derivatives
CP981_RS01100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP981_RS01125	COG1819	glycosyl
CP981_RS01165	COG1131	(ABC) transporter
CP981_RS01185	COG1595	DNA-templated transcription, initiation
CP981_RS01205	COG2046	Belongs to the sulfate adenylyltransferase family
CP981_RS01205	COG0529	Catalyzes the synthesis of activated sulfate
CP981_RS01215	COG0604	alcohol dehydrogenase
CP981_RS01230	COG0302	gtp cyclohydrolase
CP981_RS01245	COG3387	PFAM Glycoside hydrolase 15-related
CP981_RS01265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP981_RS01280	COG0069	glutamate synthase activity
CP981_RS01305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP981_RS01315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CP981_RS01315	COG0617	tRNA 3'-terminal CCA addition
CP981_RS01315	COG3620	sequence-specific DNA binding
CP981_RS01320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CP981_RS01325	COG0022	dehydrogenase e1 component
CP981_RS01370	COG0667	Aldo Keto reductase
CP981_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS01445	COG2890	protein-(glutamine-N5) methyltransferase activity
CP981_RS01450	COG0277	FAD linked oxidase domain protein
CP981_RS01450	COG0247	lactate metabolic process
CP981_RS01455	COG0028	Belongs to the TPP enzyme family
CP981_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
CP981_RS01470	COG0300	oxidoreductase activity
CP981_RS01520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP981_RS01565	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CP981_RS01580	COG1280	lysine exporter protein (LysE YggA)
CP981_RS01595	COG0832	Belongs to the urease beta subunit family
CP981_RS01595	COG0831	urea catabolic process
CP981_RS01600	COG0804	urea catabolic process
CP981_RS01610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP981_RS01615	COG0829	nickel cation binding
CP981_RS01650	COG0477	Major facilitator Superfamily
CP981_RS01720	COG0740	serine-type endopeptidase activity
CP981_RS01750	COG3251	PFAM MbtH domain protein
CP981_RS01760	COG0069	glutamate synthase activity
CP981_RS01770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CP981_RS01770	COG2124	cytochrome p450
CP981_RS01790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP981_RS01810	COG0513	Belongs to the DEAD box helicase family
CP981_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS01835	COG2897	thiosulfate sulfurtransferase activity
CP981_RS01845	COG0626	cystathionine gamma-synthase activity
CP981_RS01880	COG2226	methyltransferase
CP981_RS01905	COG1509	lysine 2,3-aminomutase activity
CP981_RS01915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP981_RS01925	COG0745	RESPONSE REGULATOR receiver
CP981_RS01970	COG2124	cytochrome p450
CP981_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS02090	COG3842	ATPase activity
CP981_RS02100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS02190	COG1819	glycosyl
CP981_RS02195	COG2135	peptidase activity
CP981_RS02235	COG2172	sigma factor antagonist activity
CP981_RS02240	COG1366	Belongs to the anti-sigma-factor antagonist family
CP981_RS02245	COG1366	Belongs to the anti-sigma-factor antagonist family
CP981_RS02260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP981_RS02270	COG3629	intracellular signal transduction
CP981_RS02280	COG0475	glutathione-regulated potassium exporter activity
CP981_RS02285	COG0542	response to heat
CP981_RS02290	COG0778	Nitroreductase
CP981_RS02295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP981_RS02300	COG0066	3-isopropylmalate dehydratase activity
CP981_RS02305	COG0010	Belongs to the arginase family
CP981_RS02310	COG0473	3-isopropylmalate dehydrogenase activity
CP981_RS02315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP981_RS02325	COG1509	lysine 2,3-aminomutase activity
CP981_RS02330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS02335	COG3186	Phenylalanine-4-hydroxylase
CP981_RS02340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP981_RS02390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP981_RS02390	COG0515	serine threonine protein kinase
CP981_RS02425	COG1132	(ABC) transporter
CP981_RS02445	COG3655	Transcriptional regulator
CP981_RS02450	COG2318	DinB family
CP981_RS02525	COG1051	belongs to the nudix hydrolase family
CP981_RS02530	COG0477	Major facilitator Superfamily
CP981_RS02575	COG1573	uracil-dna glycosylase
CP981_RS02625	COG0277	FAD linked oxidase domain protein
CP981_RS02635	COG2172	sigma factor antagonist activity
CP981_RS02635	COG2208	phosphoserine phosphatase activity
CP981_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
CP981_RS02640	COG1129	ABC transporter
CP981_RS02645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP981_RS02785	COG4191	Histidine kinase
CP981_RS02820	COG0384	phenazine biosynthesis protein PhzF
CP981_RS02835	COG1121	(ABC) transporter
CP981_RS02850	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS02855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP981_RS02870	COG2814	Major facilitator Superfamily
CP981_RS02905	COG0517	IMP dehydrogenase activity
CP981_RS02905	COG0516	GMP reductase activity
CP981_RS02920	COG0516	GMP reductase activity
CP981_RS02920	COG0517	IMP dehydrogenase activity
CP981_RS02925	COG0516	GMP reductase activity
CP981_RS02925	COG0517	IMP dehydrogenase activity
CP981_RS02930	COG1278	Cold shock
CP981_RS02935	COG0513	Belongs to the DEAD box helicase family
CP981_RS02955	COG4221	oxidoreductase activity
CP981_RS02965	COG3424	synthase
CP981_RS02970	COG0443	Heat shock 70 kDa protein
CP981_RS02975	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP981_RS03035	COG2197	response regulator
CP981_RS03040	COG1132	(ABC) transporter
CP981_RS03045	COG1132	(ABC) transporter
CP981_RS03055	COG0515	serine threonine protein kinase
CP981_RS03120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CP981_RS03125	COG1414	Transcriptional regulator
CP981_RS03130	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP981_RS03155	COG1968	undecaprenyl-diphosphatase activity
CP981_RS03180	COG1113	amino acid transport
CP981_RS03205	COG0277	FAD linked oxidase domain protein
CP981_RS03235	COG4213	ABC transporter substrate-binding protein
CP981_RS03245	COG4214	carbohydrate transport
CP981_RS03265	COG2326	polyphosphate kinase activity
CP981_RS03290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP981_RS03305	COG0006	proline dipeptidase activity
CP981_RS03310	COG1802	Transcriptional regulator
CP981_RS03355	COG0183	Belongs to the thiolase family
CP981_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS03365	COG1960	acyl-CoA dehydrogenase activity
CP981_RS03370	COG1960	acyl-CoA dehydrogenase activity
CP981_RS03390	COG0542	response to heat
CP981_RS03410	COG3591	Belongs to the peptidase S1B family
CP981_RS03410	COG1864	DNA RNA non-specific endonuclease
CP981_RS03440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP981_RS03450	COG3290	protein histidine kinase activity
CP981_RS03455	COG4565	transcriptional regulatory protein
CP981_RS03465	COG2186	Transcriptional regulator
CP981_RS03490	COG1556	Lactate utilization protein
CP981_RS03495	COG1139	Iron-sulfur cluster binding protein
CP981_RS03500	COG0247	lactate metabolic process
CP981_RS03505	COG1620	l-lactate permease
CP981_RS03520	COG1595	DNA-templated transcription, initiation
CP981_RS03540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP981_RS03555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP981_RS03580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP981_RS03585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP981_RS03605	COG2268	Band 7 protein
CP981_RS03610	COG1595	DNA-templated transcription, initiation
CP981_RS03615	COG1902	pentaerythritol trinitrate reductase activity
CP981_RS03620	COG3135	benzoate transporter
CP981_RS03625	COG0626	cystathionine gamma-synthase activity
CP981_RS03635	COG2423	ornithine cyclodeaminase activity
CP981_RS03710	COG1120	ATPase activity
CP981_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS03770	COG2274	protein secretion by the type I secretion system
CP981_RS03790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP981_RS03790	COG1796	DNA polymerase
CP981_RS03805	COG0583	DNA-binding transcription factor activity
CP981_RS03810	COG0156	8-amino-7-oxononanoate synthase activity
CP981_RS03815	COG1063	alcohol dehydrogenase
CP981_RS03845	COG2318	DinB family
CP981_RS03865	COG0745	RESPONSE REGULATOR receiver
CP981_RS03870	COG1024	Enoyl-CoA hydratase
CP981_RS03870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP981_RS03885	COG0477	Major facilitator Superfamily
CP981_RS03920	COG3585	molybdate ion transport
CP981_RS03970	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP981_RS04000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP981_RS04025	COG0438	transferase activity, transferring glycosyl groups
CP981_RS04050	COG0640	Transcriptional regulator
CP981_RS04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP981_RS04130	COG0386	Belongs to the glutathione peroxidase family
CP981_RS04145	COG1132	(ABC) transporter
CP981_RS04155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP981_RS04180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP981_RS04295	COG0483	inositol monophosphate 1-phosphatase activity
CP981_RS04315	COG1846	Transcriptional regulator
CP981_RS04355	COG2267	carboxylic ester hydrolase activity
CP981_RS04370	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS04375	COG0477	Major facilitator Superfamily
CP981_RS04385	COG0154	amidase activity
CP981_RS04400	COG1191	sigma factor activity
CP981_RS04435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP981_RS04445	COG4221	oxidoreductase activity
CP981_RS04460	COG2304	oxidoreductase activity
CP981_RS04465	COG2197	response regulator
CP981_RS04470	COG4585	Histidine kinase
CP981_RS04510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CP981_RS04515	COG0154	amidase activity
CP981_RS04555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS04565	COG3321	synthase
CP981_RS04565	COG0604	alcohol dehydrogenase
CP981_RS04575	COG0604	alcohol dehydrogenase
CP981_RS04575	COG3321	synthase
CP981_RS04585	COG3321	synthase
CP981_RS04585	COG0604	alcohol dehydrogenase
CP981_RS04595	COG3321	synthase
CP981_RS04595	COG0604	alcohol dehydrogenase
CP981_RS04610	COG2197	response regulator
CP981_RS04625	COG2197	response regulator
CP981_RS04630	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS04635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP981_RS04690	COG3548	integral membrane protein
CP981_RS04700	COG1280	lysine exporter protein (LysE YggA)
CP981_RS04705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP981_RS04710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CP981_RS04745	COG0738	Major facilitator superfamily
CP981_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS04770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS04790	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS04795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP981_RS04795	COG0825	malonyl-CoA metabolic process
CP981_RS04800	COG0583	DNA-binding transcription factor activity
CP981_RS04805	COG0697	spore germination
CP981_RS04880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP981_RS04880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP981_RS04890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP981_RS04910	COG1716	ATPase activity
CP981_RS04935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP981_RS04970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP981_RS04980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP981_RS04990	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP981_RS05000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP981_RS05005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP981_RS05020	COG0596	Alpha beta hydrolase
CP981_RS05055	COG2146	nitrite reductase [NAD(P)H] activity
CP981_RS05060	COG1414	Transcriptional regulator
CP981_RS05085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CP981_RS05105	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP981_RS05110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP981_RS05120	COG0477	Major facilitator Superfamily
CP981_RS05140	COG0438	transferase activity, transferring glycosyl groups
CP981_RS05230	COG1605	Chorismate mutase
CP981_RS05255	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS05265	COG2070	2-Nitropropane dioxygenase
CP981_RS05280	COG0515	serine threonine protein kinase
CP981_RS05290	COG1960	acyl-CoA dehydrogenase activity
CP981_RS05310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS05315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS05320	COG1120	ATPase activity
CP981_RS05325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP981_RS05330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP981_RS05340	COG2814	Major facilitator Superfamily
CP981_RS05345	COG4264	IucA IucC family
CP981_RS05360	COG0243	molybdopterin cofactor binding
CP981_RS05370	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP981_RS05380	COG2111	Na H antiporter
CP981_RS05380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP981_RS05390	COG1006	Multisubunit Na H antiporter MnhC subunit
CP981_RS05395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS05410	COG1793	dna ligase
CP981_RS05410	COG3285	dna ligase
CP981_RS05435	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP981_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS05470	COG0783	Belongs to the Dps family
CP981_RS05550	COG2376	Dihydroxyacetone kinase
CP981_RS05555	COG1461	Dihydroxyacetone kinase
CP981_RS05600	COG0395	ABC-type sugar transport system, permease component
CP981_RS05605	COG1063	alcohol dehydrogenase
CP981_RS05620	COG0789	Transcriptional regulator
CP981_RS05635	COG1793	dna ligase
CP981_RS05640	COG0277	FAD linked oxidase domain protein
CP981_RS05645	COG3224	Antibiotic biosynthesis monooxygenase
CP981_RS05650	COG0590	tRNA wobble adenosine to inosine editing
CP981_RS05670	COG0647	UMP catabolic process
CP981_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS05805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP981_RS05810	COG0463	Glycosyl transferase, family 2
CP981_RS05825	COG0633	Ferredoxin
CP981_RS05825	COG3217	Mosc domain protein beta barrel domain protein
CP981_RS05845	COG0464	growth
CP981_RS05855	COG1349	DNA-binding transcription factor activity
CP981_RS05920	COG1940	carbohydrate kinase activity
CP981_RS05925	COG2223	nitrite transmembrane transporter activity
CP981_RS05940	COG2197	response regulator
CP981_RS05945	COG4585	Histidine kinase
CP981_RS05950	COG0445	tRNA wobble uridine modification
CP981_RS05970	COG0395	ABC-type sugar transport system, permease component
CP981_RS05975	COG1175	transmembrane transport
CP981_RS05985	COG3345	alpha-galactosidase
CP981_RS06020	COG2318	DinB family
CP981_RS06025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP981_RS06075	COG0584	glycerophosphoryl diester phosphodiesterase
CP981_RS06085	COG0765	amino acid transport
CP981_RS06115	COG0671	phosphoesterase, PA-phosphatase related
CP981_RS06160	COG2197	response regulator
CP981_RS06170	COG1222	aaa ATPase
CP981_RS06180	COG3903	Transcriptional regulator
CP981_RS06180	COG3629	intracellular signal transduction
CP981_RS06265	COG0583	DNA-binding transcription factor activity
CP981_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS06275	COG0583	DNA-binding transcription factor activity
CP981_RS06305	COG0583	DNA-binding transcription factor activity
CP981_RS06315	COG0667	Aldo Keto reductase
CP981_RS06375	COG1760	l-serine dehydratase
CP981_RS06385	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS06400	COG3335	DDE superfamily endonuclease
CP981_RS06460	COG1857	crispr-associated protein
CP981_RS06500	COG1674	ftsk spoiiie
CP981_RS06590	COG0438	transferase activity, transferring glycosyl groups
CP981_RS06595	COG0584	glycerophosphoryl diester phosphodiesterase
CP981_RS06620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP981_RS06650	COG1278	Cold shock
CP981_RS06675	COG0513	Belongs to the DEAD box helicase family
CP981_RS06680	COG1278	Cold shock
CP981_RS06725	COG4974	Belongs to the 'phage' integrase family
CP981_RS06750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP981_RS06770	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS06775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CP981_RS06785	COG2192	nodulation
CP981_RS06790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CP981_RS06800	COG0546	phosphoglycolate phosphatase activity
CP981_RS06805	COG4566	intracellular signal transduction
CP981_RS06870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP981_RS06875	COG0140	phosphoribosyl-ATP diphosphatase activity
CP981_RS06880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP981_RS06885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP981_RS06885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP981_RS06890	COG3201	nicotinamide mononucleotide transporter
CP981_RS06905	COG1090	epimerase
CP981_RS06910	COG1846	Transcriptional regulator
CP981_RS06910	COG1940	carbohydrate kinase activity
CP981_RS06915	COG2223	nitrite transmembrane transporter activity
CP981_RS06930	COG1335	isochorismatase
CP981_RS06945	COG2233	PERMEase
CP981_RS06965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP981_RS06975	COG0477	Major facilitator Superfamily
CP981_RS06985	COG0531	amino acid
CP981_RS07005	COG2390	Transcriptional regulator
CP981_RS07010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP981_RS07020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP981_RS07035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP981_RS07060	COG0284	orotidine-5'-phosphate decarboxylase activity
CP981_RS07065	COG0167	dihydroorotate dehydrogenase activity
CP981_RS07070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP981_RS07075	COG0505	Belongs to the CarA family
CP981_RS07085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP981_RS07090	COG0540	Belongs to the ATCase OTCase family
CP981_RS07095	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP981_RS07105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP981_RS07110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP981_RS07115	COG0006	proline dipeptidase activity
CP981_RS07125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP981_RS07130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP981_RS07135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP981_RS07140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP981_RS07145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP981_RS07160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP981_RS07165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP981_RS07185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP981_RS07205	COG0124	histidyl-tRNA synthetase
CP981_RS07215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP981_RS07220	COG1196	nuclear chromosome segregation
CP981_RS07225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP981_RS07230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP981_RS07235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP981_RS07240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP981_RS07250	COG2255	four-way junction helicase activity
CP981_RS07255	COG0632	four-way junction helicase activity
CP981_RS07260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP981_RS07265	COG0217	transcriptional regulatory protein
CP981_RS07270	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP981_RS07275	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP981_RS07285	COG0438	transferase activity, transferring glycosyl groups
CP981_RS07290	COG1560	Kdo2-lipid A biosynthetic process
CP981_RS07295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP981_RS07330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP981_RS07345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP981_RS07390	COG0456	acetyltransferase
CP981_RS07400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP981_RS07445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP981_RS07445	COG0515	serine threonine protein kinase
CP981_RS07455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP981_RS07455	COG1648	precorrin-2 dehydrogenase activity
CP981_RS07460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP981_RS07475	COG1464	Belongs to the NlpA lipoprotein family
CP981_RS07480	COG2011	ABC-type metal ion transport system permease component
CP981_RS07485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP981_RS07510	COG0584	glycerophosphoryl diester phosphodiesterase
CP981_RS07515	COG0204	Acyl-transferase
CP981_RS07515	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS07525	COG0477	Major facilitator Superfamily
CP981_RS07535	COG0165	Argininosuccinate lyase
CP981_RS07540	COG0137	argininosuccinate synthase activity
CP981_RS07555	COG1720	tRNA m6t6A37 methyltransferase activity
CP981_RS07560	COG0668	transmembrane transport
CP981_RS07565	COG1438	arginine binding
CP981_RS07570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP981_RS07575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP981_RS07580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP981_RS07585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP981_RS07590	COG0596	Alpha beta hydrolase
CP981_RS07605	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS07640	COG0697	spore germination
CP981_RS07650	COG1649	PFAM Uncharacterised BCR, COG1649
CP981_RS07710	COG1051	belongs to the nudix hydrolase family
CP981_RS07725	COG0072	phenylalanine-tRNA ligase activity
CP981_RS07725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP981_RS07730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP981_RS07735	COG5002	protein histidine kinase activity
CP981_RS07740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP981_RS07745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP981_RS07750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP981_RS07755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP981_RS07765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP981_RS07810	COG2186	Transcriptional regulator
CP981_RS07815	COG0531	amino acid
CP981_RS07820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP981_RS07850	COG0517	IMP dehydrogenase activity
CP981_RS07850	COG4175	Glycine betaine
CP981_RS07855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP981_RS07895	COG0805	protein transport
CP981_RS07900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP981_RS07930	COG0545	Peptidyl-prolyl cis-trans isomerase
CP981_RS07935	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP981_RS07945	COG1609	Transcriptional regulator
CP981_RS07950	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP981_RS07955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP981_RS07970	COG4122	O-methyltransferase activity
CP981_RS07975	COG1222	aaa ATPase
CP981_RS08000	COG1994	Peptidase M50
CP981_RS08000	COG0517	IMP dehydrogenase activity
CP981_RS08010	COG2197	response regulator
CP981_RS08020	COG4166	transmembrane transport
CP981_RS08025	COG0546	phosphoglycolate phosphatase activity
CP981_RS08030	COG0646	methionine synthase
CP981_RS08030	COG1410	methionine synthase
CP981_RS08035	COG1414	Transcriptional regulator
CP981_RS08040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP981_RS08045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP981_RS08050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP981_RS08060	COG2186	Transcriptional regulator
CP981_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS08085	COG1129	ABC transporter
CP981_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS08100	COG4948	Mandelate Racemase Muconate Lactonizing
CP981_RS08110	COG0215	cysteine-tRNA ligase activity
CP981_RS08130	COG0598	Magnesium transport protein CorA
CP981_RS08140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS08145	COG0667	Aldo Keto reductase
CP981_RS08175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP981_RS08185	COG0564	pseudouridine synthase activity
CP981_RS08190	COG0515	serine threonine protein kinase
CP981_RS08190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP981_RS08225	COG0488	(ABC) transporter
CP981_RS08230	COG2124	cytochrome p450
CP981_RS08240	COG0745	RESPONSE REGULATOR receiver
CP981_RS08245	COG2205	protein histidine kinase activity
CP981_RS08285	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP981_RS08315	COG3963	phosphatidate phosphatase activity
CP981_RS08320	COG1309	transcriptional regulator
CP981_RS08325	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS08335	COG3876	Protein conserved in bacteria
CP981_RS08340	COG0477	Major facilitator Superfamily
CP981_RS08430	COG2851	Citrate transporter
CP981_RS08435	COG1309	transcriptional regulator
CP981_RS08440	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP981_RS08445	COG2188	Transcriptional regulator
CP981_RS08450	COG2814	Major facilitator Superfamily
CP981_RS08450	COG0477	Major facilitator Superfamily
CP981_RS08480	COG0583	DNA-binding transcription factor activity
CP981_RS08510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CP981_RS08525	COG1309	transcriptional regulator
CP981_RS08545	COG1834	amidinotransferase
CP981_RS08550	COG1725	Transcriptional regulator
CP981_RS08555	COG0367	asparagine synthase
CP981_RS08575	COG1522	sequence-specific DNA binding
CP981_RS08580	COG0531	amino acid
CP981_RS08610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP981_RS08615	COG0587	DNA-directed DNA polymerase activity
CP981_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS08650	COG0330	HflC and HflK could
CP981_RS08660	COG1799	cell septum assembly
CP981_RS08665	COG1960	acyl-CoA dehydrogenase activity
CP981_RS08670	COG0477	Major facilitator Superfamily
CP981_RS08680	COG0671	phosphoesterase, PA-phosphatase related
CP981_RS08690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP981_RS08705	COG0438	transferase activity, transferring glycosyl groups
CP981_RS08715	COG3583	domain protein
CP981_RS08730	COG1160	GTP binding
CP981_RS08740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP981_RS08760	COG1187	pseudouridine synthase activity
CP981_RS08765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP981_RS08770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP981_RS08785	COG0686	Belongs to the AlaDH PNT family
CP981_RS08795	COG0494	nUDIX hydrolase
CP981_RS08800	COG0504	CTP synthase activity
CP981_RS08805	COG3387	PFAM Glycoside hydrolase 15-related
CP981_RS08835	COG3795	YCII-related domain
CP981_RS08840	COG4941	Belongs to the sigma-70 factor family
CP981_RS08850	COG0497	DNA recombination
CP981_RS08860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP981_RS08880	COG1120	ATPase activity
CP981_RS08885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS08890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS08905	COG0647	UMP catabolic process
CP981_RS08920	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP981_RS08960	COG2094	Belongs to the DNA glycosylase MPG family
CP981_RS08970	COG1881	PFAM PEBP family protein
CP981_RS08995	COG1119	ATPase activity
CP981_RS09015	COG2197	response regulator
CP981_RS09020	COG4585	Histidine kinase
CP981_RS09030	COG0842	Transport permease protein
CP981_RS09030	COG1131	(ABC) transporter
CP981_RS09030	COG1716	ATPase activity
CP981_RS09035	COG3830	Belongs to the UPF0237 family
CP981_RS09035	COG0560	Phosphoserine phosphatase
CP981_RS09055	COG2186	Transcriptional regulator
CP981_RS09060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP981_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS09075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP981_RS09080	COG0798	PFAM Bile acid sodium symporter
CP981_RS09085	COG0640	Transcriptional regulator
CP981_RS09100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP981_RS09120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP981_RS09125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP981_RS09160	COG3340	Belongs to the peptidase S51 family
CP981_RS09165	COG1819	glycosyl
CP981_RS09195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP981_RS09210	COG3387	PFAM Glycoside hydrolase 15-related
CP981_RS09260	COG0488	(ABC) transporter
CP981_RS09275	COG0235	Class ii aldolase
CP981_RS09290	COG1653	transport
CP981_RS09310	COG1492	cobalamin metabolic process
CP981_RS09325	COG1797	cobyrinic acid a,c-diamide synthase activity
CP981_RS09335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CP981_RS09360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP981_RS09365	COG1917	Cupin 2, conserved barrel domain protein
CP981_RS09375	COG1902	pentaerythritol trinitrate reductase activity
CP981_RS09405	COG1414	Transcriptional regulator
CP981_RS09420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP981_RS09425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP981_RS09430	COG2261	transglycosylase associated protein
CP981_RS09440	COG2226	methyltransferase
CP981_RS09475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP981_RS09485	COG2171	N-acyltransferase activity
CP981_RS09490	COG3226	Transcriptional regulator
CP981_RS09495	COG2076	Multidrug Resistance protein
CP981_RS09505	COG0822	iron-sulfur transferase activity
CP981_RS09510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP981_RS09515	COG0396	ATPase activity
CP981_RS09540	COG1131	(ABC) transporter
CP981_RS09565	COG0109	protoheme IX farnesyltransferase activity
CP981_RS09575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP981_RS09590	COG0363	glucosamine-6-phosphate deaminase activity
CP981_RS09595	COG0166	Belongs to the GPI family
CP981_RS09610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP981_RS09615	COG0149	triose-phosphate isomerase activity
CP981_RS09620	COG0126	phosphoglycerate kinase activity
CP981_RS09625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP981_RS09630	COG1481	regulation of sporulation
CP981_RS09635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP981_RS09640	COG1660	Displays ATPase and GTPase activities
CP981_RS09645	COG0322	excinuclease ABC activity
CP981_RS09670	COG1609	Transcriptional regulator
CP981_RS09680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP981_RS09725	COG0556	nucleotide-excision repair
CP981_RS09730	COG0584	glycerophosphoryl diester phosphodiesterase
CP981_RS09780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP981_RS09810	COG0237	dephospho-CoA kinase activity
CP981_RS09830	COG2226	methyltransferase
CP981_RS09835	COG1643	Atp-dependent helicase
CP981_RS09870	COG2050	protein possibly involved in aromatic compounds catabolism
CP981_RS09880	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP981_RS09945	COG1917	Cupin 2, conserved barrel domain protein
CP981_RS09945	COG4977	sequence-specific DNA binding
CP981_RS09955	COG0366	Alpha amylase catalytic
CP981_RS09955	COG1470	cell adhesion involved in biofilm formation
CP981_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP981_RS09995	COG3467	pyridoxamine 5'-phosphate
CP981_RS10010	COG0640	Transcriptional regulator
CP981_RS10025	COG0069	glutamate synthase activity
CP981_RS10025	COG0067	glutamate synthase
CP981_RS10025	COG0070	glutamate synthase
CP981_RS10055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP981_RS10065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP981_RS10075	COG0159	tryptophan synthase activity
CP981_RS10080	COG0133	tryptophan synthase activity
CP981_RS10090	COG0134	indole-3-glycerol-phosphate synthase activity
CP981_RS10115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP981_RS10125	COG0583	DNA-binding transcription factor activity
CP981_RS10135	COG1053	succinate dehydrogenase
CP981_RS10140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP981_RS10160	COG0107	imidazoleglycerol-phosphate synthase activity
CP981_RS10165	COG0251	oxidation-reduction process
CP981_RS10170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP981_RS10175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP981_RS10180	COG0131	Imidazoleglycerol-phosphate dehydratase
CP981_RS10185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP981_RS10190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP981_RS10205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP981_RS10225	COG1432	Conserved Protein
CP981_RS10230	COG0587	DNA-directed DNA polymerase activity
CP981_RS10285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP981_RS10295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP981_RS10300	COG3599	regulation of cell shape
CP981_RS10310	COG1799	cell septum assembly
CP981_RS10330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP981_RS10335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP981_RS10345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP981_RS10350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP981_RS10355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP981_RS10360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP981_RS10375	COG0275	rRNA processing
CP981_RS10385	COG0714	Associated with various cellular activities
CP981_RS10405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP981_RS10425	COG1309	transcriptional regulator
CP981_RS10435	COG1233	COG1233 Phytoene dehydrogenase and related
CP981_RS10450	COG0352	thiamine-phosphate diphosphorylase activity
CP981_RS10465	COG2022	thiamine diphosphate biosynthetic process
CP981_RS10465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP981_RS10475	COG2022	thiamine diphosphate biosynthetic process
CP981_RS10480	COG2815	serine threonine protein kinase
CP981_RS10480	COG0515	serine threonine protein kinase
CP981_RS10485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP981_RS10495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP981_RS10500	COG2193	ferroxidase activity
CP981_RS10510	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP981_RS10520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP981_RS10525	COG0205	6-phosphofructokinase activity
CP981_RS10530	COG2197	response regulator
CP981_RS10560	COG1940	carbohydrate kinase activity
CP981_RS10570	COG0003	Pfam Anion-transporting ATPase
CP981_RS10590	COG0438	transferase activity, transferring glycosyl groups
CP981_RS10640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP981_RS10645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP981_RS10650	COG0723	plastoquinol--plastocyanin reductase activity
CP981_RS10655	COG2010	Cytochrome c
CP981_RS10660	COG1845	cytochrome c oxidase, subunit III
CP981_RS10670	COG1376	ErfK ybiS ycfS ynhG family protein
CP981_RS10680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP981_RS10685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP981_RS10695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS10715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP981_RS10725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS10730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP981_RS10735	COG2197	response regulator
CP981_RS10740	COG4585	Histidine kinase
CP981_RS10775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP981_RS10780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP981_RS10780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP981_RS10795	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP981_RS10800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP981_RS10805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP981_RS10810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP981_RS10820	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP981_RS10845	COG1090	epimerase
CP981_RS10860	COG0321	lipoyl(octanoyl) transferase activity
CP981_RS10865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP981_RS10905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP981_RS10925	COG1902	pentaerythritol trinitrate reductase activity
CP981_RS10925	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP981_RS10930	COG1695	Transcriptional regulator
CP981_RS10960	COG0745	RESPONSE REGULATOR receiver
CP981_RS10985	COG2197	response regulator
CP981_RS11010	COG1309	transcriptional regulator
CP981_RS11045	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CP981_RS11100	COG0366	Alpha amylase catalytic
CP981_RS11105	COG0395	ABC-type sugar transport system, permease component
CP981_RS11110	COG1175	transmembrane transport
CP981_RS11115	COG2182	Extracellular solute-binding protein
CP981_RS11120	COG0366	Alpha amylase catalytic
CP981_RS11125	COG1609	Transcriptional regulator
CP981_RS11145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP981_RS11150	COG0174	glutamine synthetase
CP981_RS11165	COG2188	Transcriptional regulator
CP981_RS11175	COG2816	NAD+ diphosphatase activity
CP981_RS11280	COG0174	glutamine synthetase
CP981_RS11285	COG2132	Multicopper oxidase
CP981_RS11290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP981_RS11290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP981_RS11295	COG2814	Major facilitator Superfamily
CP981_RS11305	COG1309	transcriptional regulator
CP981_RS11310	COG0477	Major facilitator Superfamily
CP981_RS11315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP981_RS11335	COG1994	Peptidase M50
CP981_RS11355	COG1175	transmembrane transport
CP981_RS11370	COG2186	Transcriptional regulator
CP981_RS11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP981_RS11405	COG5398	heme oxygenase
CP981_RS11420	COG2837	iron assimilation
CP981_RS11425	COG0672	)-iron permease
CP981_RS11450	COG1834	amidinotransferase
CP981_RS11460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP981_RS11465	COG2814	Major facilitator Superfamily
CP981_RS11470	COG3540	Alkaline phosphatase
CP981_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS11495	COG3321	synthase
CP981_RS11495	COG0604	alcohol dehydrogenase
CP981_RS11505	COG2345	Transcriptional regulator
CP981_RS11510	COG1960	acyl-CoA dehydrogenase activity
CP981_RS11520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP981_RS11525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP981_RS11530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS11535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS11560	COG3629	intracellular signal transduction
CP981_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS11610	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CP981_RS11615	COG3022	response to hydroperoxide
CP981_RS11620	COG0800	Aldolase
CP981_RS11655	COG2030	dehydratase
CP981_RS11660	COG1131	(ABC) transporter
CP981_RS11670	COG4585	Histidine kinase
CP981_RS11675	COG2197	response regulator
CP981_RS11685	COG0183	Belongs to the thiolase family
CP981_RS11690	COG1960	acyl-CoA dehydrogenase activity
CP981_RS11700	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP981_RS11710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS11730	COG0438	transferase activity, transferring glycosyl groups
CP981_RS11735	COG1309	transcriptional regulator
CP981_RS11750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP981_RS11770	COG3845	ABC transporter
CP981_RS11790	COG0183	Belongs to the thiolase family
CP981_RS11795	COG2124	cytochrome p450
CP981_RS11820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP981_RS11835	COG0477	Major facilitator Superfamily
CP981_RS11850	COG3629	intracellular signal transduction
CP981_RS11850	COG3903	Transcriptional regulator
CP981_RS11950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP981_RS12000	COG1309	transcriptional regulator
CP981_RS12005	COG0662	Cupin 2, conserved barrel domain protein
CP981_RS12010	COG1072	(Pantothenic acid kinase))
CP981_RS12025	COG0596	Alpha beta hydrolase
CP981_RS12030	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CP981_RS12040	COG2259	Doxx family
CP981_RS12050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP981_RS12070	COG0583	DNA-binding transcription factor activity
CP981_RS12090	COG2186	Transcriptional regulator
CP981_RS12155	COG0582	viral genome integration into host DNA
CP981_RS12175	COG2186	Transcriptional regulator
CP981_RS12180	COG4948	Mandelate Racemase Muconate Lactonizing
CP981_RS12185	COG0800	Aldolase
CP981_RS12210	COG4585	Histidine kinase
CP981_RS12215	COG0586	Pfam SNARE associated Golgi protein
CP981_RS12225	COG1358	cellular component organization or biogenesis
CP981_RS12270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP981_RS12280	COG0477	Major facilitator Superfamily
CP981_RS12285	COG1309	transcriptional regulator
CP981_RS12300	COG4585	Histidine kinase
CP981_RS12305	COG2197	response regulator
CP981_RS12315	COG0667	Aldo Keto reductase
CP981_RS12320	COG0789	Transcriptional regulator
CP981_RS12345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP981_RS12350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP981_RS12355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS12405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS12415	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP981_RS12420	COG1129	ABC transporter
CP981_RS12430	COG1609	Transcriptional regulator
CP981_RS12435	COG1764	response to oxidative stress
CP981_RS12440	COG2130	NADP-dependent
CP981_RS12450	COG0477	Major facilitator Superfamily
CP981_RS12480	COG0500	methyltransferase
CP981_RS12485	COG4981	capsule polysaccharide biosynthetic process
CP981_RS12520	COG1077	Cell shape determining protein MreB Mrl
CP981_RS12525	COG0588	phosphoglycerate mutase activity
CP981_RS12530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP981_RS12575	COG1070	Carbohydrate kinase
CP981_RS12580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP981_RS12585	COG0358	DNA primase activity
CP981_RS12600	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP981_RS12610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP981_RS12640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP981_RS12695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP981_RS12695	COG2146	nitrite reductase [NAD(P)H] activity
CP981_RS12710	COG0640	Transcriptional regulator
CP981_RS12790	COG1175	transmembrane transport
CP981_RS12795	COG0395	ABC-type sugar transport system, permease component
CP981_RS12800	COG2175	clavaminate synthase activity
CP981_RS12815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP981_RS12815	COG0574	Belongs to the PEP-utilizing enzyme family
CP981_RS12820	COG0519	Catalyzes the synthesis of GMP from XMP
CP981_RS12825	COG0477	Major facilitator Superfamily
CP981_RS12865	COG0477	Major facilitator Superfamily
CP981_RS12870	COG0667	Aldo Keto reductase
CP981_RS12875	COG1309	transcriptional regulator
CP981_RS12900	COG2197	response regulator
CP981_RS12915	COG0423	glycine-tRNA ligase activity
CP981_RS12925	COG1121	(ABC) transporter
CP981_RS12930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP981_RS12940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP981_RS12945	COG1381	Involved in DNA repair and RecF pathway recombination
CP981_RS13000	COG2755	lipolytic protein G-D-S-L family
CP981_RS13005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP981_RS13030	COG2211	Major facilitator Superfamily
CP981_RS13035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP981_RS13060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP981_RS13070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS13075	COG1486	melibiose metabolic process
CP981_RS13100	COG4948	Mandelate Racemase Muconate Lactonizing
CP981_RS13110	COG1234	tRNA 3'-trailer cleavage
CP981_RS13115	COG0537	adenosine 5'-monophosphoramidase activity
CP981_RS13140	COG0484	heat shock protein binding
CP981_RS13145	COG1420	regulation of RNA biosynthetic process
CP981_RS13175	COG1022	Amp-dependent synthetase and ligase
CP981_RS13180	COG0481	GTPase activity
CP981_RS13185	COG0268	Binds directly to 16S ribosomal RNA
CP981_RS13205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CP981_RS13210	COG1959	2 iron, 2 sulfur cluster binding
CP981_RS13215	COG1234	tRNA 3'-trailer cleavage
CP981_RS13220	COG1555	photosystem II stabilization
CP981_RS13225	COG1307	EDD domain protein, DegV family
CP981_RS13235	COG0495	leucyl-tRNA aminoacylation
CP981_RS13270	COG0588	phosphoglycerate mutase activity
CP981_RS13275	COG0799	negative regulation of ribosome biogenesis
CP981_RS13285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP981_RS13290	COG0501	Belongs to the peptidase M48B family
CP981_RS13305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP981_RS13315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP981_RS13325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP981_RS13330	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP981_RS13335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP981_RS13340	COG1530	ribonuclease E activity
CP981_RS13375	COG0772	Belongs to the SEDS family
CP981_RS13380	COG0768	penicillin binding
CP981_RS13395	COG1077	Cell shape determining protein MreB Mrl
CP981_RS13400	COG0105	UTP biosynthetic process
CP981_RS13410	COG0285	dihydrofolate synthase activity
CP981_RS13415	COG0768	penicillin binding
CP981_RS13420	COG0525	valine-tRNA ligase activity
CP981_RS13430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP981_RS13435	COG0740	serine-type endopeptidase activity
CP981_RS13440	COG0740	serine-type endopeptidase activity
CP981_RS13445	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP981_RS13470	COG3594	Acyltransferase
CP981_RS13480	COG4552	Acetyltransferase involved in intracellular survival and related
CP981_RS13490	COG0698	ribose 5-phosphate isomerase
CP981_RS13495	COG1113	amino acid transport
CP981_RS13505	COG1113	amino acid transport
CP981_RS13510	COG1113	amino acid transport
CP981_RS13515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP981_RS13520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP981_RS13560	COG4266	Belongs to the allantoicase family
CP981_RS13565	COG0583	DNA-binding transcription factor activity
CP981_RS13600	COG0668	transmembrane transport
CP981_RS13605	COG1846	Transcriptional regulator
CP981_RS13605	COG1940	carbohydrate kinase activity
CP981_RS13610	COG1486	melibiose metabolic process
CP981_RS13625	COG2186	Transcriptional regulator
CP981_RS13635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP981_RS13665	COG2346	COG2346, Truncated hemoglobins
CP981_RS13785	COG0513	Belongs to the DEAD box helicase family
CP981_RS13790	COG1278	Cold shock
CP981_RS13795	COG3629	intracellular signal transduction
CP981_RS13795	COG3903	Transcriptional regulator
CP981_RS13800	COG0477	Major facilitator Superfamily
CP981_RS13810	COG0302	gtp cyclohydrolase
CP981_RS13820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP981_RS13825	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS13835	COG0561	phosphatase activity
CP981_RS13840	COG0583	DNA-binding transcription factor activity
CP981_RS13855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS13880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP981_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS13890	COG5285	phytanoyl-CoA dioxygenase
CP981_RS13910	COG1113	amino acid transport
CP981_RS13935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS13975	COG0596	Alpha beta hydrolase
CP981_RS13990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP981_RS14000	COG1131	(ABC) transporter
CP981_RS14005	COG2205	protein histidine kinase activity
CP981_RS14010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS14025	COG3962	Belongs to the TPP enzyme family
CP981_RS14030	COG3718	enzyme involved in inositol metabolism
CP981_RS14040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS14050	COG0673	inositol 2-dehydrogenase activity
CP981_RS14055	COG2814	Major facilitator Superfamily
CP981_RS14060	COG3409	Peptidoglycan-binding domain 1 protein
CP981_RS14075	COG0673	inositol 2-dehydrogenase activity
CP981_RS14080	COG0586	Pfam SNARE associated Golgi protein
CP981_RS14085	COG2608	mercury ion transmembrane transporter activity
CP981_RS14100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP981_RS14115	COG0673	inositol 2-dehydrogenase activity
CP981_RS14130	COG1472	Belongs to the glycosyl hydrolase 3 family
CP981_RS14150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP981_RS14160	COG1309	transcriptional regulator
CP981_RS14165	COG0028	Belongs to the TPP enzyme family
CP981_RS14245	COG1946	Acyl-CoA thioesterase
CP981_RS14255	COG1309	transcriptional regulator
CP981_RS14260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP981_RS14275	COG1960	acyl-CoA dehydrogenase activity
CP981_RS14285	COG3415	Transposase
CP981_RS14285	COG2801	Transposase and inactivated derivatives
CP981_RS14290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS14300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP981_RS14315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP981_RS14320	COG0589	response to stress
CP981_RS14330	COG4977	sequence-specific DNA binding
CP981_RS14335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP981_RS14345	COG3979	chitinase
CP981_RS14355	COG0745	RESPONSE REGULATOR receiver
CP981_RS14365	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP981_RS14380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP981_RS14395	COG0492	ferredoxin-NADP+ reductase activity
CP981_RS14455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS14475	COG0154	amidase activity
CP981_RS14490	COG0765	amino acid transport
CP981_RS14495	COG0765	amino acid transport
CP981_RS14500	COG1126	abc transporter atp-binding protein
CP981_RS14565	COG0673	inositol 2-dehydrogenase activity
CP981_RS14580	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP981_RS14630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP981_RS14640	COG3764	Sortase (surface protein transpeptidase)
CP981_RS14645	COG2733	membrane
CP981_RS14675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP981_RS14685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP981_RS14700	COG2205	protein histidine kinase activity
CP981_RS14710	COG0477	Major facilitator Superfamily
CP981_RS14730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP981_RS14745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP981_RS14750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP981_RS14755	COG1263	PTS System
CP981_RS14760	COG1263	PTS System
CP981_RS14765	COG0463	Glycosyl transferase, family 2
CP981_RS14765	COG0457	Tetratricopeptide repeat
CP981_RS14780	COG1234	tRNA 3'-trailer cleavage
CP981_RS14805	COG1113	amino acid transport
CP981_RS14815	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP981_RS14825	COG1335	isochorismatase
CP981_RS14860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP981_RS14865	COG0222	ribosome binding
CP981_RS14880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS14880	COG2080	2 iron, 2 sulfur cluster binding
CP981_RS14890	COG0277	FAD linked oxidase domain protein
CP981_RS14895	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP981_RS14905	COG1174	glycine betaine transport
CP981_RS14915	COG1174	glycine betaine transport
CP981_RS14940	COG0477	Major facilitator Superfamily
CP981_RS14945	COG0596	Alpha beta hydrolase
CP981_RS14965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS14980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP981_RS14995	COG1678	Uncharacterized ACR, COG1678
CP981_RS15000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP981_RS15010	COG0776	regulation of translation
CP981_RS15020	COG3973	AAA domain
CP981_RS15050	COG2223	nitrite transmembrane transporter activity
CP981_RS15085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP981_RS15090	COG0793	Belongs to the peptidase S41A family
CP981_RS15095	COG2177	Part of the ABC transporter FtsEX involved in
CP981_RS15100	COG2884	Cell division ATP-binding protein ftsE
CP981_RS15115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP981_RS15120	COG0515	serine threonine protein kinase
CP981_RS15125	COG0515	serine threonine protein kinase
CP981_RS15135	COG1653	transport
CP981_RS15140	COG1175	transmembrane transport
CP981_RS15145	COG0395	ABC-type sugar transport system, permease component
CP981_RS15160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP981_RS15175	COG2226	methyltransferase
CP981_RS15190	COG1215	transferase activity, transferring glycosyl groups
CP981_RS15195	COG0463	Glycosyl transferase, family 2
CP981_RS15195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP981_RS15200	COG1309	transcriptional regulator
CP981_RS15210	COG1134	teichoic acid transport
CP981_RS15215	COG2902	Dehydrogenase
CP981_RS15220	COG0546	phosphoglycolate phosphatase activity
CP981_RS15235	COG0653	protein targeting
CP981_RS15245	COG3214	Protein conserved in bacteria
CP981_RS15250	COG2197	response regulator
CP981_RS15255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP981_RS15270	COG0823	Involved in the tonB-independent uptake of proteins
CP981_RS15275	COG5002	protein histidine kinase activity
CP981_RS15275	COG5000	phosphorelay sensor kinase activity
CP981_RS15280	COG0745	RESPONSE REGULATOR receiver
CP981_RS15285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP981_RS15305	COG0714	Associated with various cellular activities
CP981_RS15350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP981_RS15355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP981_RS15355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP981_RS15355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP981_RS15365	COG1482	cell wall glycoprotein biosynthetic process
CP981_RS15375	COG2835	tetraacyldisaccharide 4'-kinase activity
CP981_RS15380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP981_RS15415	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP981_RS15420	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP981_RS15420	COG0778	Nitroreductase
CP981_RS15450	COG1316	TRANSCRIPTIONal
CP981_RS15465	COG1316	TRANSCRIPTIONal
CP981_RS15485	COG1316	TRANSCRIPTIONal
CP981_RS15495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP981_RS15535	COG2205	protein histidine kinase activity
CP981_RS15540	COG0745	RESPONSE REGULATOR receiver
CP981_RS15545	COG3104	oligopeptide transport
CP981_RS15575	COG1366	Belongs to the anti-sigma-factor antagonist family
CP981_RS15580	COG1191	sigma factor activity
CP981_RS15585	COG1228	amidohydrolase
CP981_RS15595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP981_RS15600	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP981_RS15620	COG0842	Transport permease protein
CP981_RS15645	COG1174	glycine betaine transport
CP981_RS15650	COG1174	glycine betaine transport
CP981_RS15665	COG1609	Transcriptional regulator
CP981_RS15680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP981_RS15695	COG2755	lipolytic protein G-D-S-L family
CP981_RS15700	COG0183	Belongs to the thiolase family
CP981_RS15725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP981_RS15730	COG0297	glycogen (starch) synthase activity
CP981_RS15740	COG0577	efflux transmembrane transporter activity
CP981_RS15740	COG1136	(ABC) transporter
CP981_RS15745	COG0577	efflux transmembrane transporter activity
CP981_RS15745	COG1136	(ABC) transporter
CP981_RS15750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP981_RS15790	COG0148	phosphopyruvate hydratase activity
CP981_RS15805	COG2124	cytochrome p450
CP981_RS15815	COG2814	Major facilitator Superfamily
CP981_RS15840	COG2814	Major facilitator Superfamily
CP981_RS15850	COG1316	TRANSCRIPTIONal
CP981_RS15875	COG4585	Histidine kinase
CP981_RS15885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP981_RS15890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP981_RS15895	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP981_RS15900	COG0193	aminoacyl-tRNA hydrolase activity
CP981_RS15910	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP981_RS15920	COG1309	transcriptional regulator
CP981_RS15925	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS15945	COG2197	response regulator
CP981_RS15950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP981_RS15995	COG0488	(ABC) transporter
CP981_RS16065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP981_RS16070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP981_RS16075	COG3584	3D domain protein
CP981_RS16075	COG3583	domain protein
CP981_RS16080	COG0084	hydrolase, TatD family'
CP981_RS16110	COG1090	epimerase
CP981_RS16135	COG1122	ATPase activity
CP981_RS16145	COG0310	cobalt ion transport
CP981_RS16160	COG4946	Tricorn protease homolog
CP981_RS16160	COG0793	Belongs to the peptidase S41A family
CP981_RS16170	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS16175	COG2267	carboxylic ester hydrolase activity
CP981_RS16180	COG2072	flavoprotein involved in K transport
CP981_RS16190	COG3903	Transcriptional regulator
CP981_RS16190	COG3629	intracellular signal transduction
CP981_RS16200	COG0708	Exodeoxyribonuclease III
CP981_RS16220	COG1725	Transcriptional regulator
CP981_RS16225	COG0789	Transcriptional regulator
CP981_RS16230	COG1819	glycosyl
CP981_RS16300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS16305	COG0315	cyclic pyranopterin monophosphate synthase activity
CP981_RS16305	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP981_RS16310	COG0315	cyclic pyranopterin monophosphate synthase activity
CP981_RS16320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP981_RS16325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP981_RS16335	COG3263	regulation of cellular component size
CP981_RS16350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP981_RS16355	COG1970	mechanosensitive ion channel activity
CP981_RS16375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP981_RS16390	COG2188	Transcriptional regulator
CP981_RS16395	COG0730	response to heat
CP981_RS16450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP981_RS16480	COG1105	Belongs to the carbohydrate kinase PfkB family
CP981_RS16485	COG1349	DNA-binding transcription factor activity
CP981_RS16495	COG1247	-acetyltransferase
CP981_RS16520	COG1846	Transcriptional regulator
CP981_RS16540	COG1309	transcriptional regulator
CP981_RS16575	COG2197	response regulator
CP981_RS16585	COG0582	viral genome integration into host DNA
CP981_RS16650	COG2188	Transcriptional regulator
CP981_RS16670	COG0154	amidase activity
CP981_RS16675	COG0514	ATP-dependent DNA helicase (RecQ)
CP981_RS16700	COG1686	Belongs to the peptidase S11 family
CP981_RS16730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS16760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP981_RS16800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS16810	COG2319	Wd-40 repeat
CP981_RS16870	COG1024	Enoyl-CoA hydratase
CP981_RS16890	COG2801	Transposase and inactivated derivatives
CP981_RS16890	COG3415	Transposase
CP981_RS16910	COG1960	acyl-CoA dehydrogenase activity
CP981_RS16945	COG0259	pyridoxamine-phosphate oxidase activity
CP981_RS16970	COG1024	Enoyl-CoA hydratase
CP981_RS16985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP981_RS17000	COG1960	acyl-CoA dehydrogenase activity
CP981_RS17005	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS17020	COG1960	acyl-CoA dehydrogenase activity
CP981_RS17025	COG1960	acyl-CoA dehydrogenase activity
CP981_RS17050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP981_RS17060	COG0516	GMP reductase activity
CP981_RS17070	COG1595	DNA-templated transcription, initiation
CP981_RS17085	COG0583	DNA-binding transcription factor activity
CP981_RS17095	COG4221	oxidoreductase activity
CP981_RS17110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP981_RS17130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP981_RS17155	COG0802	atpase or kinase
CP981_RS17165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP981_RS17180	COG0736	holo-[acyl-carrier-protein] synthase activity
CP981_RS17185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP981_RS17210	COG1072	(Pantothenic acid kinase))
CP981_RS17220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP981_RS17225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP981_RS17230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP981_RS17235	COG0488	(ABC) transporter
CP981_RS17245	COG0101	tRNA pseudouridine synthase activity
CP981_RS17250	COG0203	ribosomal protein L17
CP981_RS17255	COG0202	RNA polymerase activity
CP981_RS17260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP981_RS17265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP981_RS17270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP981_RS17275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP981_RS17280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP981_RS17290	COG0563	adenylate kinase activity
CP981_RS17300	COG0200	Binds to the 23S rRNA
CP981_RS17305	COG1841	ribosomal large subunit assembly
CP981_RS17310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP981_RS17315	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP981_RS17320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP981_RS17325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP981_RS17335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP981_RS17340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP981_RS17345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP981_RS17350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP981_RS17355	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP981_RS17360	COG0255	Belongs to the universal ribosomal protein uL29 family
CP981_RS17365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP981_RS17370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP981_RS17375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP981_RS17380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP981_RS17385	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP981_RS17390	COG0089	rRNA binding
CP981_RS17395	COG0088	Forms part of the polypeptide exit tunnel
CP981_RS17400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP981_RS17405	COG0051	transcription antitermination factor activity, RNA binding
CP981_RS17410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP981_RS17415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP981_RS17420	COG0049	tRNA binding
CP981_RS17425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP981_RS17435	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP981_RS17440	COG0085	RNA polymerase activity
CP981_RS17450	COG0222	ribosome binding
CP981_RS17455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP981_RS17460	COG0081	regulation of translation
CP981_RS17465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP981_RS17470	COG0250	Participates in transcription elongation, termination and antitermination
CP981_RS17485	COG0436	Aminotransferase
CP981_RS17490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP981_RS17495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP981_RS17505	COG2030	dehydratase
CP981_RS17510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP981_RS17525	COG0402	S-adenosylhomocysteine deaminase activity
CP981_RS17530	COG0702	epimerase
CP981_RS17630	COG1666	GTP binding
CP981_RS17635	COG3304	Inner membrane component domain
CP981_RS17640	COG0501	Belongs to the peptidase M48B family
CP981_RS17645	COG1007	ATP synthesis coupled electron transport
CP981_RS17655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP981_RS17660	COG0713	ATP synthesis coupled electron transport
CP981_RS17665	COG0839	Belongs to the complex I subunit 6 family
CP981_RS17670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17675	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP981_RS17680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17715	COG4585	Histidine kinase
CP981_RS17720	COG4585	Histidine kinase
CP981_RS17730	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP981_RS17730	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP981_RS17735	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP981_RS17740	COG0702	epimerase
CP981_RS17765	COG0142	geranyltranstransferase activity
CP981_RS17790	COG1007	ATP synthesis coupled electron transport
CP981_RS17800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP981_RS17805	COG0713	ATP synthesis coupled electron transport
CP981_RS17810	COG0839	Belongs to the complex I subunit 6 family
CP981_RS17815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP981_RS17825	COG1034	ATP synthesis coupled electron transport
CP981_RS17830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP981_RS17840	COG0649	NAD binding
CP981_RS17845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP981_RS17890	COG2226	methyltransferase
CP981_RS17900	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP981_RS17910	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP981_RS17915	COG1278	Cold shock
CP981_RS17930	COG1309	transcriptional regulator
CP981_RS17940	COG1301	dicarboxylic acid transport
CP981_RS17955	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP981_RS17965	COG0163	prenyltransferase activity
CP981_RS17980	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP981_RS17985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP981_RS18010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP981_RS18015	COG1333	cytochrome c biogenesis protein
CP981_RS18020	COG0785	Cytochrome C biogenesis protein
CP981_RS18035	COG0406	alpha-ribazole phosphatase activity
CP981_RS18040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP981_RS18075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP981_RS18085	COG1742	UPF0060 membrane protein
CP981_RS18105	COG1714	RDD family
CP981_RS18110	COG1690	Belongs to the RtcB family
CP981_RS18135	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP981_RS18140	COG0018	arginyl-trna synthetase
CP981_RS18145	COG3237	CsbD-like
CP981_RS18150	COG0113	porphobilinogen synthase activity
CP981_RS18155	COG1648	precorrin-2 dehydrogenase activity
CP981_RS18155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP981_RS18160	COG0181	hydroxymethylbilane synthase activity
CP981_RS18165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP981_RS18170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP981_RS18220	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP981_RS18230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP981_RS18255	COG1846	Transcriptional regulator
CP981_RS18270	COG1252	NADH dehydrogenase
CP981_RS18295	COG0579	oxidoreductase
CP981_RS18305	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP981_RS18350	COG0513	Belongs to the DEAD box helicase family
CP981_RS18390	COG1643	Atp-dependent helicase
CP981_RS18425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP981_RS18440	COG1196	nuclear chromosome segregation
CP981_RS18440	COG0739	heme binding
CP981_RS18440	COG0741	lytic transglycosylase activity
CP981_RS18450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP981_RS18455	COG0047	phosphoribosylformylglycinamidine synthase activity
CP981_RS18460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP981_RS18495	COG2197	response regulator
CP981_RS18505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP981_RS18520	COG0151	Belongs to the GarS family
CP981_RS18535	COG1802	Transcriptional regulator
CP981_RS18540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP981_RS18550	COG0693	protein deglycase activity
CP981_RS18570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP981_RS18590	COG2197	response regulator
CP981_RS18595	COG4585	Histidine kinase
CP981_RS18605	COG3844	kynureninase activity
CP981_RS18610	COG3483	tryptophan 2,3-dioxygenase activity
CP981_RS18625	COG0191	fructose-bisphosphate aldolase activity
CP981_RS18630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP981_RS18645	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP981_RS18675	COG0542	response to heat
CP981_RS18700	COG0789	Transcriptional regulator
CP981_RS18705	COG0484	heat shock protein binding
CP981_RS18710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP981_RS18715	COG0443	Heat shock 70 kDa protein
CP981_RS18720	COG0247	lactate metabolic process
CP981_RS18720	COG2181	nitrate reductase activity
CP981_RS18740	COG2755	lipolytic protein G-D-S-L family
CP981_RS18750	COG0717	Belongs to the dCTP deaminase family
CP981_RS18790	COG1136	(ABC) transporter
CP981_RS18825	COG0302	gtp cyclohydrolase
CP981_RS18880	COG2076	Multidrug Resistance protein
CP981_RS18905	COG0515	serine threonine protein kinase
CP981_RS18905	COG2815	serine threonine protein kinase
CP981_RS18940	COG0515	serine threonine protein kinase
CP981_RS18940	COG2815	serine threonine protein kinase
CP981_RS18985	COG4585	Histidine kinase
CP981_RS18990	COG2197	response regulator
CP981_RS19055	COG1316	TRANSCRIPTIONal
CP981_RS19120	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CP981_RS19170	COG0745	RESPONSE REGULATOR receiver
CP981_RS19180	COG1732	Glycine betaine
CP981_RS19185	COG1174	glycine betaine transport
CP981_RS19190	COG1174	glycine betaine transport
CP981_RS19215	COG2304	oxidoreductase activity
CP981_RS19225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP981_RS19235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP981_RS19260	COG1960	acyl-CoA dehydrogenase activity
CP981_RS19265	COG1362	aminopeptidase activity
CP981_RS19270	COG3903	Transcriptional regulator
CP981_RS19270	COG3629	intracellular signal transduction
CP981_RS19310	COG0456	acetyltransferase
CP981_RS19320	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP981_RS19325	COG0022	dehydrogenase e1 component
CP981_RS19345	COG0515	serine threonine protein kinase
CP981_RS19350	COG0515	serine threonine protein kinase
CP981_RS19370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP981_RS19385	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP981_RS19400	COG1522	sequence-specific DNA binding
CP981_RS19405	COG1309	transcriptional regulator
CP981_RS19410	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS19435	COG3396	Phenylacetate-CoA oxygenase
CP981_RS19440	COG3460	Phenylacetate-CoA oxygenase
CP981_RS19445	COG3396	Phenylacetate-CoA oxygenase
CP981_RS19450	COG2151	metal-sulfur cluster biosynthetic enzyme
CP981_RS19455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP981_RS19490	COG1733	regulation of RNA biosynthetic process
CP981_RS19495	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP981_RS19505	COG1716	ATPase activity
CP981_RS19510	COG1716	ATPase activity
CP981_RS19535	COG0515	serine threonine protein kinase
CP981_RS19540	COG3764	Sortase (surface protein transpeptidase)
CP981_RS19545	COG3764	Sortase (surface protein transpeptidase)
CP981_RS19555	COG3764	Sortase (surface protein transpeptidase)
CP981_RS19570	COG0705	Rhomboid family
CP981_RS19595	COG0515	serine threonine protein kinase
CP981_RS19625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP981_RS19630	COG0187	DNA topoisomerase II activity
CP981_RS19635	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP981_RS19640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP981_RS19645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP981_RS19650	COG0592	DNA-directed DNA polymerase activity
CP981_RS19665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP981_RS19670	COG0594	ribonuclease P activity
CP981_RS19675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP981_RS19680	COG0706	membrane insertase activity
CP981_RS19685	COG1847	R3H domain protein
CP981_RS19690	COG0357	Ribosomal RNA small subunit methyltransferase G
CP981_RS19695	COG1192	Involved in chromosome partitioning
CP981_RS19710	COG3118	belongs to the thioredoxin family
CP981_RS19715	COG0492	ferredoxin-NADP+ reductase activity
CP981_RS19725	COG1595	DNA-templated transcription, initiation
CP981_RS19735	COG0515	serine threonine protein kinase
CP981_RS19735	COG2815	serine threonine protein kinase
CP981_RS19750	COG0617	tRNA 3'-terminal CCA addition
CP981_RS19780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP981_RS19805	COG0360	Binds together with S18 to 16S ribosomal RNA
CP981_RS19810	COG0629	single-stranded DNA binding
CP981_RS19815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP981_RS19820	COG0359	binds to the 23S rRNA
CP981_RS19830	COG0534	Mate efflux family protein
CP981_RS19835	COG0305	Participates in initiation and elongation during chromosome replication
CP981_RS19860	COG4977	sequence-specific DNA binding
CP981_RS19865	COG0789	Transcriptional regulator
CP981_RS19865	COG4978	Transcriptional regulator
CP981_RS19900	COG2814	Major facilitator Superfamily
CP981_RS19940	COG0626	cystathionine gamma-synthase activity
CP981_RS19945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP981_RS19950	COG1950	PFAM Membrane protein of
CP981_RS19955	COG0662	Cupin 2, conserved barrel domain protein
CP981_RS19980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP981_RS19990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP981_RS19995	COG1609	Transcriptional regulator
CP981_RS20000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP981_RS20005	COG1271	oxidase subunit
CP981_RS20010	COG1294	oxidase, subunit
CP981_RS20015	COG4988	ABC transporter
CP981_RS20025	COG0561	phosphatase activity
CP981_RS20035	COG0501	Belongs to the peptidase M48B family
CP981_RS20045	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP981_RS20050	COG0789	Transcriptional regulator
CP981_RS20065	COG1131	(ABC) transporter
CP981_RS20085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP981_RS20090	COG2807	transmembrane transport
CP981_RS20095	COG2186	Transcriptional regulator
CP981_RS20140	COG0561	phosphatase activity
CP981_RS20145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP981_RS20150	COG0077	Prephenate dehydratase
CP981_RS20155	COG2837	iron assimilation
CP981_RS20160	COG2372	response to copper ion
CP981_RS20210	COG0006	proline dipeptidase activity
CP981_RS20235	COG0653	protein targeting
CP981_RS20250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP981_RS20320	COG0494	nUDIX hydrolase
CP981_RS20365	COG3409	Peptidoglycan-binding domain 1 protein
CP981_RS20365	COG5632	N-Acetylmuramoyl-L-alanine amidase
CP981_RS20390	COG1960	acyl-CoA dehydrogenase activity
CP981_RS20400	COG1960	acyl-CoA dehydrogenase activity
CP981_RS20415	COG1595	DNA-templated transcription, initiation
CP981_RS20420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS20435	COG0662	Cupin 2, conserved barrel domain protein
CP981_RS20485	COG3437	response regulator, receiver
CP981_RS20505	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS20510	COG0784	Response regulator, receiver
CP981_RS20555	COG2249	NAD(P)H dehydrogenase (quinone) activity
CP981_RS20575	COG3976	FMN-binding domain protein
CP981_RS20575	COG1053	succinate dehydrogenase
CP981_RS20575	COG0431	NADPH-dependent FMN reductase
CP981_RS20580	COG1132	(ABC) transporter
CP981_RS20585	COG0745	RESPONSE REGULATOR receiver
CP981_RS20590	COG2205	protein histidine kinase activity
CP981_RS20600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP981_RS20605	COG0477	Major facilitator Superfamily
CP981_RS20625	COG2353	YceI-like domain
CP981_RS20630	COG0477	Major facilitator Superfamily
CP981_RS20650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS20655	COG0402	S-adenosylhomocysteine deaminase activity
CP981_RS20675	COG1191	sigma factor activity
CP981_RS20680	COG1191	sigma factor activity
CP981_RS20715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP981_RS20735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP981_RS20765	COG2409	Drug exporters of the RND superfamily
CP981_RS20770	COG0523	cobalamin synthesis protein
CP981_RS20780	COG1064	alcohol dehydrogenase
CP981_RS20820	COG2268	Band 7 protein
CP981_RS20830	COG2226	methyltransferase
CP981_RS20835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS20860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP981_RS20865	COG1834	amidinotransferase
CP981_RS20880	COG0596	Alpha beta hydrolase
CP981_RS20890	COG0189	ligase activity
CP981_RS20915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP981_RS20925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP981_RS20935	COG2378	regulation of single-species biofilm formation
CP981_RS20940	COG0577	efflux transmembrane transporter activity
CP981_RS20940	COG1136	(ABC) transporter
CP981_RS20950	COG2197	response regulator
CP981_RS20980	COG2205	protein histidine kinase activity
CP981_RS20985	COG0745	RESPONSE REGULATOR receiver
CP981_RS21000	COG1136	(ABC) transporter
CP981_RS21000	COG0577	efflux transmembrane transporter activity
CP981_RS21005	COG1136	(ABC) transporter
CP981_RS21005	COG0577	efflux transmembrane transporter activity
CP981_RS21010	COG1132	(ABC) transporter
CP981_RS21015	COG0531	amino acid
CP981_RS21090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP981_RS21095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP981_RS21115	COG1595	DNA-templated transcription, initiation
CP981_RS21145	COG2124	cytochrome p450
CP981_RS21150	COG1309	transcriptional regulator
CP981_RS21155	COG1215	transferase activity, transferring glycosyl groups
CP981_RS21160	COG1316	TRANSCRIPTIONal
CP981_RS21180	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CP981_RS21190	COG2188	Transcriptional regulator
CP981_RS21195	COG2319	Wd-40 repeat
CP981_RS21195	COG4249	Peptidase C14 caspase catalytic subunit p20
CP981_RS21200	COG0546	phosphoglycolate phosphatase activity
CP981_RS21290	COG1609	Transcriptional regulator
CP981_RS21305	COG1408	metallophosphoesterase
CP981_RS21315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP981_RS21330	COG0003	Pfam Anion-transporting ATPase
CP981_RS21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP981_RS21390	COG2267	carboxylic ester hydrolase activity
CP981_RS21400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP981_RS21405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP981_RS21465	COG1205	dead DEAH box helicase
CP981_RS21465	COG1111	helicase
CP981_RS21470	COG1366	Belongs to the anti-sigma-factor antagonist family
CP981_RS21475	COG2172	sigma factor antagonist activity
CP981_RS21485	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP981_RS21495	COG2890	protein-(glutamine-N5) methyltransferase activity
CP981_RS21520	COG1754	DNA topoisomerase type I activity
CP981_RS21520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP981_RS21525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP981_RS21530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP981_RS21580	COG1074	ATP-dependent DNA helicase activity
CP981_RS21610	COG0270	DNA (cytosine-5-)-methyltransferase activity
CP981_RS21660	COG0644	oxidoreductase
CP981_RS21675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS21680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS21685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS21720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS21735	COG2175	clavaminate synthase activity
CP981_RS21740	COG3251	PFAM MbtH domain protein
CP981_RS21745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP981_RS21765	COG0475	glutathione-regulated potassium exporter activity
CP981_RS21780	COG2124	cytochrome p450
CP981_RS21785	COG3629	intracellular signal transduction
CP981_RS21785	COG3903	Transcriptional regulator
CP981_RS21810	COG2205	protein histidine kinase activity
CP981_RS21815	COG0745	RESPONSE REGULATOR receiver
CP981_RS21835	COG2197	response regulator
CP981_RS21840	COG0584	glycerophosphoryl diester phosphodiesterase
CP981_RS21845	COG3594	Acyltransferase
CP981_RS21865	COG1309	transcriptional regulator
CP981_RS21915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP981_RS21915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP981_RS21920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP981_RS21925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP981_RS21930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP981_RS21935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP981_RS21940	COG0254	rRNA binding
CP981_RS21950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP981_RS21970	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS21975	COG2318	DinB family
CP981_RS21985	COG0076	glutamate decarboxylase activity
CP981_RS21990	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP981_RS22000	COG0789	Transcriptional regulator
CP981_RS22005	COG0393	Putative heavy-metal-binding
CP981_RS22020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP981_RS22025	COG2027	D-alanyl-D-alanine carboxypeptidase
CP981_RS22035	COG0037	tRNA processing
CP981_RS22050	COG0302	gtp cyclohydrolase
CP981_RS22060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP981_RS22060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP981_RS22075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP981_RS22080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP981_RS22100	COG3226	Transcriptional regulator
CP981_RS22105	COG0649	NAD binding
CP981_RS22115	COG4585	Histidine kinase
CP981_RS22120	COG2197	response regulator
CP981_RS22125	COG0640	Transcriptional regulator
CP981_RS22135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP981_RS22150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP981_RS22155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP981_RS22165	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP981_RS22185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP981_RS22220	COG0739	heme binding
CP981_RS22235	COG2205	protein histidine kinase activity
CP981_RS22240	COG0745	RESPONSE REGULATOR receiver
CP981_RS22250	COG1595	DNA-templated transcription, initiation
CP981_RS22255	COG1194	a g-specific adenine glycosylase
CP981_RS22295	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP981_RS22315	COG0248	Ppx GppA phosphatase
CP981_RS22320	COG1082	Xylose isomerase domain protein TIM barrel
CP981_RS22330	COG0129	dihydroxy-acid dehydratase activity
CP981_RS22355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP981_RS22355	COG0515	serine threonine protein kinase
CP981_RS22380	COG1595	DNA-templated transcription, initiation
CP981_RS22385	COG1252	NADH dehydrogenase
CP981_RS22405	COG1129	ABC transporter
CP981_RS22405	COG0842	Transport permease protein
CP981_RS22415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP981_RS22420	COG0180	Tryptophanyl-tRNA synthetase
CP981_RS22480	COG0739	heme binding
CP981_RS22480	COG1196	nuclear chromosome segregation
CP981_RS22480	COG0741	lytic transglycosylase activity
CP981_RS22485	COG0671	phosphoesterase, PA-phosphatase related
CP981_RS22490	COG0277	FAD linked oxidase domain protein
CP981_RS22510	COG1937	Protein conserved in bacteria
CP981_RS22520	COG0306	phosphate transporter
CP981_RS22525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP981_RS22540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP981_RS22620	COG2890	protein-(glutamine-N5) methyltransferase activity
CP981_RS22635	COG0667	Aldo Keto reductase
CP981_RS22650	COG2226	methyltransferase
CP981_RS22665	COG0431	NADPH-dependent FMN reductase
CP981_RS22685	COG1490	D-aminoacyl-tRNA deacylase activity
CP981_RS22695	COG0735	belongs to the Fur family
CP981_RS22705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CP981_RS22710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP981_RS22715	COG3485	protocatechuate 3,4-dioxygenase
CP981_RS22735	COG2897	thiosulfate sulfurtransferase activity
CP981_RS22765	COG0745	RESPONSE REGULATOR receiver
CP981_RS22770	COG1609	Transcriptional regulator
CP981_RS22775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP981_RS22810	COG0737	Belongs to the 5'-nucleotidase family
CP981_RS22815	COG0456	acetyltransferase
CP981_RS22820	COG1131	(ABC) transporter
CP981_RS22830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP981_RS22855	COG0667	Aldo Keto reductase
CP981_RS22870	COG0438	transferase activity, transferring glycosyl groups
CP981_RS22885	COG0588	phosphoglycerate mutase activity
CP981_RS22900	COG5002	protein histidine kinase activity
CP981_RS22920	COG1329	Transcriptional regulator
CP981_RS22925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP981_RS22930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP981_RS22940	COG0215	cysteine-tRNA ligase activity
CP981_RS22965	COG3842	ATPase activity
CP981_RS22985	COG2205	protein histidine kinase activity
CP981_RS22990	COG0745	RESPONSE REGULATOR receiver
CP981_RS23065	COG2197	response regulator
CP981_RS23080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP981_RS23130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CP981_RS23135	COG0463	Glycosyl transferase, family 2
CP981_RS23150	COG1278	Cold shock
CP981_RS23155	COG0459	protein refolding
CP981_RS23180	COG0745	RESPONSE REGULATOR receiver
CP981_RS23190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP981_RS23225	COG3142	Participates in the control of copper homeostasis
CP981_RS23230	COG0515	serine threonine protein kinase
CP981_RS23230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP981_RS23235	COG3973	AAA domain
CP981_RS23250	COG1061	Type III restriction enzyme res subunit
CP981_RS23285	COG1278	Cold shock
CP981_RS23290	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP981_RS23295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP981_RS23305	COG2814	Major facilitator Superfamily
CP981_RS23350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP981_RS23365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP981_RS23375	COG2252	PERMEase
CP981_RS23400	COG0667	Aldo Keto reductase
CP981_RS23445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP981_RS23450	COG2378	regulation of single-species biofilm formation
CP981_RS23460	COG0277	FAD linked oxidase domain protein
CP981_RS23460	COG0247	lactate metabolic process
CP981_RS23520	COG0583	DNA-binding transcription factor activity
CP981_RS23525	COG5006	permease, DMT superfamily
CP981_RS23540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP981_RS23580	COG0259	pyridoxamine-phosphate oxidase activity
CP981_RS23590	COG4821	SIS domain
CP981_RS23600	COG0596	Alpha beta hydrolase
CP981_RS23600	COG2945	thiolester hydrolase activity
CP981_RS23675	COG0515	serine threonine protein kinase
CP981_RS23700	COG0519	Catalyzes the synthesis of GMP from XMP
CP981_RS23700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP981_RS23710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP981_RS23715	COG2423	ornithine cyclodeaminase activity
CP981_RS23755	COG0515	serine threonine protein kinase
CP981_RS23755	COG2815	serine threonine protein kinase
CP981_RS23765	COG2197	response regulator
CP981_RS23775	COG0791	NLP P60 protein
CP981_RS23805	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS23825	COG0714	Associated with various cellular activities
CP981_RS23840	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP981_RS23860	COG0045	succinate-CoA ligase (ADP-forming) activity
CP981_RS23890	COG0138	bifunctional purine biosynthesis protein purh
CP981_RS23905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP981_RS23935	COG0039	L-malate dehydrogenase activity
CP981_RS23990	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS24000	COG4175	Glycine betaine
CP981_RS24000	COG0517	IMP dehydrogenase activity
CP981_RS24025	COG0640	Transcriptional regulator
CP981_RS24035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS24040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS24050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS24055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS24060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS24065	COG0456	acetyltransferase
CP981_RS24120	COG0754	glutathionylspermidine amidase activity
CP981_RS24160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP981_RS24165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP981_RS24170	COG0180	Tryptophanyl-tRNA synthetase
CP981_RS24180	COG1295	ribonuclease BN
CP981_RS24185	COG1686	Belongs to the peptidase S11 family
CP981_RS24195	COG1408	metallophosphoesterase
CP981_RS24235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP981_RS24240	COG1053	succinate dehydrogenase
CP981_RS24250	COG2009	succinate dehydrogenase
CP981_RS24260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP981_RS24280	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS24280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS24305	COG3265	gluconokinase activity
CP981_RS24325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP981_RS24335	COG1216	Glycosyl transferase, family 2
CP981_RS24345	COG1083	cytidylyl-transferase
CP981_RS24350	COG2089	acid synthase
CP981_RS24360	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP981_RS24360	COG1473	amidohydrolase
CP981_RS24365	COG1744	ABC transporter substrate-binding protein PnrA-like
CP981_RS24370	COG3845	ABC transporter
CP981_RS24375	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP981_RS24380	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP981_RS24430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS24465	COG2814	Major facilitator Superfamily
CP981_RS24470	COG0583	DNA-binding transcription factor activity
CP981_RS24480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP981_RS24505	COG2205	protein histidine kinase activity
CP981_RS24510	COG0745	RESPONSE REGULATOR receiver
CP981_RS24515	COG1595	DNA-templated transcription, initiation
CP981_RS24535	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS24540	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS24545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP981_RS24555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP981_RS24590	COG4770	biotin carboxylase activity
CP981_RS24600	COG0693	protein deglycase activity
CP981_RS24610	COG0424	maF-like protein
CP981_RS24615	COG0768	penicillin binding
CP981_RS24625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP981_RS24635	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP981_RS24640	COG1024	Enoyl-CoA hydratase
CP981_RS24650	COG2986	histidine ammonia-lyase
CP981_RS24670	COG0454	-acetyltransferase
CP981_RS24670	COG0456	acetyltransferase
CP981_RS24685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS24690	COG2197	response regulator
CP981_RS24695	COG4585	Histidine kinase
CP981_RS24720	COG4221	oxidoreductase activity
CP981_RS24775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP981_RS24795	COG1595	DNA-templated transcription, initiation
CP981_RS24800	COG2255	four-way junction helicase activity
CP981_RS24805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP981_RS24820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP981_RS24830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP981_RS24845	COG1331	Highly conserved protein containing a thioredoxin domain
CP981_RS24855	COG0154	amidase activity
CP981_RS24865	COG0789	Transcriptional regulator
CP981_RS24880	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP981_RS24890	COG0436	Aminotransferase
CP981_RS24900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP981_RS24910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS24915	COG1414	Transcriptional regulator
CP981_RS24920	COG0251	oxidation-reduction process
CP981_RS24925	COG2610	gluconate transmembrane transporter activity
CP981_RS24960	COG2894	cell division
CP981_RS25000	COG2885	chlorophyll binding
CP981_RS25015	COG0667	Aldo Keto reductase
CP981_RS25020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP981_RS25025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP981_RS25040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS25045	COG0450	alkyl hydroperoxide reductase
CP981_RS25055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP981_RS25070	COG1136	(ABC) transporter
CP981_RS25090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP981_RS25115	COG0114	fumarate hydratase activity
CP981_RS25135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP981_RS25135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP981_RS25160	COG0778	Nitroreductase
CP981_RS25165	COG1722	exodeoxyribonuclease VII activity
CP981_RS25170	COG1570	exodeoxyribonuclease VII activity
CP981_RS25180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP981_RS25190	COG0012	GTP binding
CP981_RS25305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP981_RS25310	COG1414	Transcriptional regulator
CP981_RS25340	COG0531	amino acid
CP981_RS25390	COG1217	gtp-binding protein TYPA
CP981_RS25400	COG0601	transmembrane transport
CP981_RS25405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP981_RS25410	COG0444	Belongs to the ABC transporter superfamily
CP981_RS25415	COG4608	Belongs to the ABC transporter superfamily
CP981_RS25420	COG4608	Belongs to the ABC transporter superfamily
CP981_RS25425	COG0444	Belongs to the ABC transporter superfamily
CP981_RS25435	COG4166	transmembrane transport
CP981_RS25440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP981_RS25460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP981_RS25480	COG4585	Histidine kinase
CP981_RS25485	COG2197	response regulator
CP981_RS25525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP981_RS25530	COG1611	Belongs to the LOG family
CP981_RS25535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP981_RS25545	COG0519	Catalyzes the synthesis of GMP from XMP
CP981_RS25550	COG1024	Enoyl-CoA hydratase
CP981_RS25565	COG1595	DNA-templated transcription, initiation
CP981_RS25575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP981_RS25580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP981_RS25615	COG0598	Magnesium transport protein CorA
CP981_RS25625	COG2814	Major facilitator Superfamily
CP981_RS25640	COG2095	MarC family integral membrane protein
CP981_RS25645	COG1432	Conserved Protein
CP981_RS25690	COG0596	Alpha beta hydrolase
CP981_RS25690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP981_RS25750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP981_RS25760	COG2362	D-Aminopeptidase
CP981_RS25795	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP981_RS25850	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP981_RS25860	COG1615	UPF0182 protein
CP981_RS25900	COG0753	catalase activity
CP981_RS25905	COG0517	IMP dehydrogenase activity
CP981_RS25905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CP981_RS25910	COG0483	inositol monophosphate 1-phosphatase activity
CP981_RS25920	COG2076	Multidrug Resistance protein
CP981_RS25930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP981_RS25940	COG2135	peptidase activity
CP981_RS25950	COG3800	Transcriptional regulator
CP981_RS25950	COG1396	sequence-specific DNA binding
CP981_RS25955	COG1595	DNA-templated transcription, initiation
CP981_RS25960	COG5662	AntiSigma factor
CP981_RS25965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP981_RS25965	COG2199	diguanylate cyclase activity
CP981_RS25980	COG0242	peptide deformylase activity
CP981_RS25985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP981_RS25995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP981_RS26020	COG2188	Transcriptional regulator
CP981_RS26025	COG2182	Extracellular solute-binding protein
CP981_RS26030	COG1175	transmembrane transport
CP981_RS26035	COG0395	ABC-type sugar transport system, permease component
CP981_RS26040	COG1472	Belongs to the glycosyl hydrolase 3 family
CP981_RS26045	COG0363	glucosamine-6-phosphate deaminase activity
CP981_RS26050	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS26055	COG1309	transcriptional regulator
CP981_RS26070	COG1597	lipid kinase activity
CP981_RS26105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CP981_RS26125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CP981_RS26145	COG2066	Belongs to the glutaminase family
CP981_RS26160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP981_RS26175	COG0477	Major facilitator Superfamily
CP981_RS26185	COG0598	Magnesium transport protein CorA
CP981_RS26190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CP981_RS26195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP981_RS26200	COG1993	acr, cog1993
CP981_RS26205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP981_RS26245	COG2226	methyltransferase
CP981_RS26270	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS26275	COG1126	abc transporter atp-binding protein
CP981_RS26290	COG0281	malic enzyme
CP981_RS26295	COG0604	alcohol dehydrogenase
CP981_RS26355	COG2255	four-way junction helicase activity
CP981_RS26380	COG0567	Dehydrogenase, E1 component
CP981_RS26380	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP981_RS26385	COG2205	protein histidine kinase activity
CP981_RS26390	COG0745	RESPONSE REGULATOR receiver
CP981_RS26435	COG1357	PFAM Pentapeptide repeats (8 copies)
CP981_RS26440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP981_RS26515	COG1119	ATPase activity
CP981_RS26525	COG0768	penicillin binding
CP981_RS26540	COG2124	cytochrome p450
CP981_RS26555	COG0018	arginyl-trna synthetase
CP981_RS26560	COG0019	diaminopimelate decarboxylase activity
CP981_RS26565	COG0460	homoserine dehydrogenase
CP981_RS26570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP981_RS26575	COG0083	homoserine kinase activity
CP981_RS26590	COG0254	rRNA binding
CP981_RS26595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP981_RS26600	COG2890	protein-(glutamine-N5) methyltransferase activity
CP981_RS26610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP981_RS26615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP981_RS26635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP981_RS26640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP981_RS26645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP981_RS26650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP981_RS26655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP981_RS26660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP981_RS26665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP981_RS26675	COG2197	response regulator
CP981_RS26705	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS26720	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP981_RS26775	COG0183	Belongs to the thiolase family
CP981_RS26790	COG0745	RESPONSE REGULATOR receiver
CP981_RS26850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS26850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS26855	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP981_RS26855	COG0515	serine threonine protein kinase
CP981_RS26860	COG2205	protein histidine kinase activity
CP981_RS26870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP981_RS26915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP981_RS26920	COG0280	phosphate acetyltransferase
CP981_RS26920	COG0857	belongs to the CobB CobQ family
CP981_RS26925	COG0205	6-phosphofructokinase activity
CP981_RS26930	COG0577	efflux transmembrane transporter activity
CP981_RS26930	COG1136	(ABC) transporter
CP981_RS26935	COG0577	efflux transmembrane transporter activity
CP981_RS26935	COG1136	(ABC) transporter
CP981_RS26945	COG0395	ABC-type sugar transport system, permease component
CP981_RS26960	COG4565	transcriptional regulatory protein
CP981_RS26965	COG3290	protein histidine kinase activity
CP981_RS26970	COG1301	dicarboxylic acid transport
CP981_RS26975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP981_RS26985	COG0366	Alpha amylase catalytic
CP981_RS26990	COG0366	Alpha amylase catalytic
CP981_RS26995	COG4585	Histidine kinase
CP981_RS27000	COG2197	response regulator
CP981_RS27020	COG1132	(ABC) transporter
CP981_RS27035	COG1132	(ABC) transporter
CP981_RS27040	COG1132	(ABC) transporter
CP981_RS27055	COG1376	ErfK ybiS ycfS ynhG family protein
CP981_RS27075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP981_RS27075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP981_RS27080	COG0785	Cytochrome C biogenesis protein
CP981_RS27085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP981_RS27100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP981_RS27110	COG0438	transferase activity, transferring glycosyl groups
CP981_RS27115	COG0745	RESPONSE REGULATOR receiver
CP981_RS27130	COG0671	phosphoesterase, PA-phosphatase related
CP981_RS27140	COG1760	l-serine dehydratase
CP981_RS27145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP981_RS27150	COG0509	glycine decarboxylation via glycine cleavage system
CP981_RS27155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP981_RS27180	COG0747	negative chemotaxis
CP981_RS27190	COG0444	Belongs to the ABC transporter superfamily
CP981_RS27195	COG4608	Belongs to the ABC transporter superfamily
CP981_RS27200	COG0308	aminopeptidase N
CP981_RS27205	COG2860	membrane
CP981_RS27230	COG3629	intracellular signal transduction
CP981_RS27230	COG3903	Transcriptional regulator
CP981_RS27270	COG0482	sulfurtransferase activity
CP981_RS27280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP981_RS27290	COG4221	oxidoreductase activity
CP981_RS27310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP981_RS27325	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP981_RS27330	COG0154	amidase activity
CP981_RS27340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP981_RS27350	COG0667	Aldo Keto reductase
CP981_RS27370	COG3511	phospholipase C
CP981_RS27375	COG2409	Drug exporters of the RND superfamily
CP981_RS27395	COG1672	PFAM Archaeal ATPase
CP981_RS27395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP981_RS27405	COG2133	pyrroloquinoline quinone binding
CP981_RS27410	COG0667	Aldo Keto reductase
CP981_RS27420	COG3300	MHYT domain
CP981_RS27420	COG5001	Diguanylate cyclase
CP981_RS27435	COG0440	acetolactate synthase activity
CP981_RS27440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP981_RS27445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP981_RS27455	COG1309	transcriptional regulator
CP981_RS27470	COG0506	proline dehydrogenase activity
CP981_RS27475	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS27485	COG0473	3-isopropylmalate dehydrogenase activity
CP981_RS27490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP981_RS27500	COG0831	urea catabolic process
CP981_RS27500	COG0832	Belongs to the urease beta subunit family
CP981_RS27505	COG0804	urea catabolic process
CP981_RS27510	COG2957	Belongs to the agmatine deiminase family
CP981_RS27515	COG1309	transcriptional regulator
CP981_RS27525	COG0477	Major facilitator Superfamily
CP981_RS27535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP981_RS27540	COG2353	YceI-like domain
CP981_RS27545	COG5492	domain, Protein
CP981_RS27550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP981_RS27575	COG2018	Roadblock/LC7 domain
CP981_RS27595	COG2018	Roadblock/LC7 domain
CP981_RS27610	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP981_RS27615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP981_RS27620	COG1011	Hydrolase
CP981_RS27655	COG1414	Transcriptional regulator
CP981_RS27660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP981_RS27665	COG0066	3-isopropylmalate dehydratase activity
CP981_RS27675	COG0776	regulation of translation
CP981_RS27685	COG1920	GTP binding
CP981_RS27695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP981_RS27700	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP981_RS27720	COG0351	phosphomethylpyrimidine kinase
CP981_RS27725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP981_RS27730	COG1461	Dihydroxyacetone kinase
CP981_RS27735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CP981_RS27740	COG0742	ribosomal rna small subunit methyltransferase
CP981_RS27745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP981_RS27760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP981_RS27765	COG0571	ribonuclease III activity
CP981_RS27770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP981_RS27775	COG1733	regulation of RNA biosynthetic process
CP981_RS27785	COG2340	Cysteine-rich secretory protein family
CP981_RS27790	COG1254	Belongs to the acylphosphatase family
CP981_RS27805	COG0477	Major facilitator Superfamily
CP981_RS27815	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CP981_RS27845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP981_RS27865	COG0228	four-way junction DNA binding
CP981_RS27870	COG1837	Belongs to the UPF0109 family
CP981_RS27875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP981_RS27880	COG0336	Belongs to the RNA methyltransferase TrmD family
CP981_RS27885	COG0335	large ribosomal subunit rRNA binding
CP981_RS27890	COG0681	Belongs to the peptidase S26 family
CP981_RS27900	COG0681	Belongs to the peptidase S26 family
CP981_RS27905	COG0681	Belongs to the peptidase S26 family
CP981_RS27920	COG0792	nuclease activity
CP981_RS27935	COG1191	sigma factor activity
CP981_RS27945	COG4942	peptidase
CP981_RS27945	COG1388	LysM domain
CP981_RS27955	COG0052	Belongs to the universal ribosomal protein uS2 family
CP981_RS27960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP981_RS27965	COG0528	UMP kinase activity
CP981_RS27970	COG0233	cytoplasmic translational termination
CP981_RS27975	COG0575	Belongs to the CDS family
CP981_RS27985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP981_RS27995	COG4208	sulfate ABC transporter
CP981_RS28000	COG3842	ATPase activity
CP981_RS28015	COG1309	transcriptional regulator
CP981_RS28035	COG4181	ATPase activity
CP981_RS28040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP981_RS28050	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS28060	COG0583	DNA-binding transcription factor activity
CP981_RS28075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP981_RS28085	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS28095	COG3842	ATPase activity
CP981_RS28100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP981_RS28105	COG1177	transmembrane transport
CP981_RS28110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP981_RS28135	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS28145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP981_RS28150	COG0750	zinc metalloprotease
CP981_RS28155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP981_RS28170	COG0442	prolyl-tRNA aminoacylation
CP981_RS28190	COG0779	Required for maturation of 30S ribosomal subunits
CP981_RS28205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP981_RS28215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP981_RS28220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP981_RS28235	COG0596	Alpha beta hydrolase
CP981_RS28240	COG0455	bacterial-type flagellum organization
CP981_RS28290	COG1404	Belongs to the peptidase S8 family
CP981_RS28335	COG1674	ftsk spoiiie
CP981_RS28345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP981_RS28350	COG1185	polyribonucleotide nucleotidyltransferase activity
CP981_RS28355	COG0612	Peptidase, M16
CP981_RS28360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP981_RS28380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP981_RS28385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP981_RS28390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP981_RS28430	COG2208	phosphoserine phosphatase activity
CP981_RS28430	COG2770	Histidine kinase
CP981_RS28435	COG2205	protein histidine kinase activity
CP981_RS28435	COG4999	Histidine kinase
CP981_RS28435	COG3850	Histidine kinase
CP981_RS28435	COG3437	response regulator, receiver
CP981_RS28445	COG1674	ftsk spoiiie
CP981_RS28455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP981_RS28465	COG1058	Belongs to the CinA family
CP981_RS28465	COG1546	Belongs to the CinA family
CP981_RS28470	COG1396	sequence-specific DNA binding
CP981_RS28475	COG0783	Belongs to the Dps family
CP981_RS28485	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS28490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP981_RS28495	COG1201	RNA secondary structure unwinding
CP981_RS28525	COG0628	permease
CP981_RS28530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP981_RS28550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP981_RS28555	COG0765	amino acid transport
CP981_RS28560	COG0765	amino acid transport
CP981_RS28565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP981_RS28570	COG1126	abc transporter atp-binding protein
CP981_RS28580	COG2205	protein histidine kinase activity
CP981_RS28585	COG1278	Cold shock
CP981_RS28595	COG2259	Doxx family
CP981_RS28600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP981_RS28615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP981_RS28625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP981_RS28630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP981_RS28640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP981_RS28675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP981_RS28680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP981_RS28685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP981_RS28705	COG3226	Transcriptional regulator
CP981_RS28710	COG0154	amidase activity
CP981_RS28725	COG0488	(ABC) transporter
CP981_RS28740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP981_RS28775	COG2186	Transcriptional regulator
CP981_RS28780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP981_RS28795	COG0187	DNA topoisomerase II activity
CP981_RS28805	COG4585	Histidine kinase
CP981_RS28810	COG2197	response regulator
CP981_RS28820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP981_RS28825	COG4565	transcriptional regulatory protein
CP981_RS28830	COG3290	protein histidine kinase activity
CP981_RS28845	COG0372	Belongs to the citrate synthase family
CP981_RS28855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP981_RS28860	COG0612	Peptidase, M16
CP981_RS28875	COG1802	Transcriptional regulator
CP981_RS28880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP981_RS28900	COG1435	thymidine kinase activity
CP981_RS28940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP981_RS28945	COG0483	inositol monophosphate 1-phosphatase activity
CP981_RS28950	COG0745	RESPONSE REGULATOR receiver
CP981_RS28955	COG2205	protein histidine kinase activity
CP981_RS28980	COG0756	dUTP diphosphatase activity
CP981_RS28995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP981_RS29000	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP981_RS29005	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP981_RS29040	COG0569	domain protein
CP981_RS29050	COG0531	amino acid
CP981_RS29055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP981_RS29105	COG0515	serine threonine protein kinase
CP981_RS29105	COG2815	serine threonine protein kinase
CP981_RS29115	COG0210	DNA helicase
CP981_RS29155	COG0745	RESPONSE REGULATOR receiver
CP981_RS29160	COG2205	protein histidine kinase activity
CP981_RS29165	COG1136	(ABC) transporter
CP981_RS29170	COG0577	efflux transmembrane transporter activity
CP981_RS29205	COG0306	phosphate transporter
CP981_RS29220	COG4977	sequence-specific DNA binding
CP981_RS29225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP981_RS29245	COG0302	gtp cyclohydrolase
CP981_RS29285	COG3387	PFAM Glycoside hydrolase 15-related
CP981_RS29300	COG1191	sigma factor activity
CP981_RS29315	COG1191	sigma factor activity
CP981_RS29320	COG2814	Major facilitator Superfamily
CP981_RS29370	COG2124	cytochrome p450
CP981_RS29375	COG2124	cytochrome p450
CP981_RS29405	COG4585	Histidine kinase
CP981_RS29410	COG2197	response regulator
CP981_RS29415	COG0598	Magnesium transport protein CorA
CP981_RS29420	COG1799	cell septum assembly
CP981_RS29450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP981_RS29460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP981_RS29465	COG0531	amino acid
CP981_RS29475	COG1024	Enoyl-CoA hydratase
CP981_RS29505	COG0546	phosphoglycolate phosphatase activity
CP981_RS29540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP981_RS29560	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP981_RS29565	COG1595	DNA-templated transcription, initiation
CP981_RS29580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP981_RS29590	COG1653	transport
CP981_RS29595	COG1175	transmembrane transport
CP981_RS29600	COG0395	ABC-type sugar transport system, permease component
CP981_RS29610	COG4213	ABC transporter substrate-binding protein
CP981_RS29620	COG4214	carbohydrate transport
CP981_RS29625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP981_RS29630	COG0531	amino acid
CP981_RS29650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS29650	COG1024	Enoyl-CoA hydratase
CP981_RS29655	COG0183	Belongs to the thiolase family
CP981_RS29665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP981_RS29680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP981_RS29690	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP981_RS29695	COG0183	Belongs to the thiolase family
CP981_RS29700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP981_RS29705	COG3253	May function as heme-dependent peroxidase
CP981_RS29770	COG1136	(ABC) transporter
CP981_RS29785	COG2197	response regulator
CP981_RS29790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP981_RS29795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP981_RS29855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP981_RS29865	COG0693	protein deglycase activity
CP981_RS29885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP981_RS29890	COG0583	DNA-binding transcription factor activity
CP981_RS29930	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS29965	COG1309	transcriptional regulator
CP981_RS29970	COG0477	Major facilitator Superfamily
CP981_RS29980	COG2318	DinB family
CP981_RS30005	COG4585	Histidine kinase
CP981_RS30010	COG2197	response regulator
CP981_RS30015	COG1136	(ABC) transporter
CP981_RS30020	COG0577	efflux transmembrane transporter activity
CP981_RS30020	COG1136	(ABC) transporter
CP981_RS30030	COG0587	DNA-directed DNA polymerase activity
CP981_RS30065	COG2267	carboxylic ester hydrolase activity
CP981_RS30070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP981_RS30075	COG1609	Transcriptional regulator
CP981_RS30095	COG0366	Alpha amylase catalytic
CP981_RS30105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP981_RS30110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CP981_RS30135	COG0529	Catalyzes the synthesis of activated sulfate
CP981_RS30140	COG0175	sulfate reduction
CP981_RS30180	COG1960	acyl-CoA dehydrogenase activity
CP981_RS30190	COG2814	Major facilitator Superfamily
CP981_RS30200	COG1414	Transcriptional regulator
CP981_RS30210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CP981_RS30215	COG3485	protocatechuate 3,4-dioxygenase
CP981_RS30220	COG3485	protocatechuate 3,4-dioxygenase
CP981_RS30225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP981_RS30230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP981_RS30240	COG2770	Histidine kinase
CP981_RS30240	COG2208	phosphoserine phosphatase activity
CP981_RS30285	COG1309	transcriptional regulator
CP981_RS30315	COG2080	2 iron, 2 sulfur cluster binding
CP981_RS30320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP981_RS30325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS30350	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS30355	COG3511	phospholipase C
CP981_RS30360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP981_RS30365	COG0667	Aldo Keto reductase
CP981_RS30370	COG1376	ErfK ybiS ycfS ynhG family protein
CP981_RS30400	COG0842	Transport permease protein
CP981_RS30400	COG1131	(ABC) transporter
CP981_RS30400	COG1716	ATPase activity
CP981_RS30405	COG2233	PERMEase
CP981_RS30415	COG1215	transferase activity, transferring glycosyl groups
CP981_RS30420	COG2755	lipolytic protein G-D-S-L family
CP981_RS30420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP981_RS30460	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS30465	COG2318	DinB family
CP981_RS30470	COG1162	GTPase activity
CP981_RS30490	COG0028	Belongs to the TPP enzyme family
CP981_RS30540	COG3511	phospholipase C
CP981_RS30560	COG1802	Transcriptional regulator
CP981_RS30590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS30595	COG2252	PERMEase
CP981_RS30605	COG4552	Acetyltransferase involved in intracellular survival and related
CP981_RS30610	COG2318	DinB family
CP981_RS30620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS30625	COG0583	DNA-binding transcription factor activity
CP981_RS30640	COG2197	response regulator
CP981_RS30645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP981_RS30650	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS30670	COG2315	Protein conserved in bacteria
CP981_RS30675	COG2226	methyltransferase
CP981_RS30690	COG0753	catalase activity
CP981_RS30695	COG2084	Dehydrogenase
CP981_RS30700	COG3622	Belongs to the hyi family
CP981_RS30720	COG2351	hydroxyisourate hydrolase activity
CP981_RS30740	COG2233	PERMEase
CP981_RS30755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP981_RS30760	COG1473	amidohydrolase
CP981_RS30770	COG0174	glutamine synthetase
CP981_RS30785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP981_RS30810	COG1414	Transcriptional regulator
CP981_RS30820	COG1953	Uracil, thiamine, allantoin
CP981_RS30825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP981_RS30855	COG0800	Aldolase
CP981_RS30870	COG2188	Transcriptional regulator
CP981_RS30885	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP981_RS30895	COG1940	carbohydrate kinase activity
CP981_RS30940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP981_RS30965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP981_RS31055	COG2814	Major facilitator Superfamily
CP981_RS31065	COG1733	regulation of RNA biosynthetic process
CP981_RS31155	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS31170	COG0076	glutamate decarboxylase activity
CP981_RS31195	COG0657	acetylesterase activity
CP981_RS31215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP981_RS31230	COG3391	amine dehydrogenase activity
CP981_RS31235	COG0154	amidase activity
CP981_RS31260	COG0583	DNA-binding transcription factor activity
CP981_RS31400	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS31405	COG0583	DNA-binding transcription factor activity
CP981_RS31420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP981_RS31425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP981_RS31445	COG1126	abc transporter atp-binding protein
CP981_RS31450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP981_RS31455	COG0765	amino acid transport
CP981_RS31460	COG0765	amino acid transport
CP981_RS31470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP981_RS31475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS31485	COG0435	Glutathione S-transferase
CP981_RS31495	COG2409	Drug exporters of the RND superfamily
CP981_RS31505	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS31510	COG0531	amino acid
CP981_RS31520	COG0405	Gamma-glutamyltransferase
CP981_RS31530	COG1335	isochorismatase
CP981_RS31545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP981_RS31555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP981_RS31560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP981_RS31580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP981_RS31585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP981_RS31600	COG0483	inositol monophosphate 1-phosphatase activity
CP981_RS31635	COG1929	Belongs to the glycerate kinase type-1 family
CP981_RS31645	COG0688	phosphatidylethanolamine metabolic process
CP981_RS31650	COG1960	acyl-CoA dehydrogenase activity
CP981_RS31660	COG2301	Belongs to the HpcH HpaI aldolase family
CP981_RS31665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS31665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP981_RS31680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS31720	COG2814	Major facilitator Superfamily
CP981_RS31745	COG2362	D-Aminopeptidase
CP981_RS31750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP981_RS31755	COG4946	Tricorn protease homolog
CP981_RS31755	COG1506	peptidase
CP981_RS31755	COG0823	Involved in the tonB-independent uptake of proteins
CP981_RS31760	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP981_RS31775	COG2124	cytochrome p450
CP981_RS31780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS31820	COG1597	lipid kinase activity
CP981_RS31825	COG0456	acetyltransferase
CP981_RS31845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP981_RS31855	COG0531	amino acid
CP981_RS31890	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP981_RS31895	COG1295	ribonuclease BN
CP981_RS31910	COG4106	trans-aconitate 2-methyltransferase activity
CP981_RS31920	COG0656	L-ascorbic acid biosynthetic process
CP981_RS31935	COG0583	DNA-binding transcription factor activity
CP981_RS31950	COG0604	alcohol dehydrogenase
CP981_RS31960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP981_RS31970	COG0287	Prephenate dehydrogenase
CP981_RS31970	COG1605	Chorismate mutase
CP981_RS31975	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS32000	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS32030	COG1309	transcriptional regulator
CP981_RS32100	COG2205	protein histidine kinase activity
CP981_RS32105	COG0745	RESPONSE REGULATOR receiver
CP981_RS32130	COG3226	Transcriptional regulator
CP981_RS32145	COG1846	Transcriptional regulator
CP981_RS32155	COG1309	transcriptional regulator
CP981_RS32170	COG1309	transcriptional regulator
CP981_RS32180	COG1349	DNA-binding transcription factor activity
CP981_RS32190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP981_RS32195	COG2814	Major facilitator Superfamily
CP981_RS32205	COG0154	amidase activity
CP981_RS32210	COG1515	deoxyribonuclease V activity
CP981_RS32215	COG3268	Saccharopine dehydrogenase
CP981_RS32230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP981_RS32235	COG1960	acyl-CoA dehydrogenase activity
CP981_RS32240	COG0183	Belongs to the thiolase family
CP981_RS32245	COG1024	Enoyl-CoA hydratase
CP981_RS32245	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS32255	COG1113	amino acid transport
CP981_RS32275	COG2197	response regulator
CP981_RS32280	COG3568	Endonuclease Exonuclease Phosphatase
CP981_RS32305	COG2936	dipeptidyl-peptidase activity
CP981_RS32315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP981_RS32355	COG2183	response to ionizing radiation
CP981_RS32365	COG4977	sequence-specific DNA binding
CP981_RS32395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP981_RS32430	COG1134	teichoic acid transport
CP981_RS32435	COG1562	ergosterol biosynthetic process
CP981_RS32445	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP981_RS32455	COG1657	PFAM Prenyltransferase squalene oxidase
CP981_RS32480	COG2365	Tyrosine phosphatase family
CP981_RS32485	COG2755	lipolytic protein G-D-S-L family
CP981_RS32510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP981_RS32520	COG0596	Alpha beta hydrolase
CP981_RS32560	COG2018	Roadblock/LC7 domain
CP981_RS32580	COG1960	acyl-CoA dehydrogenase activity
CP981_RS32585	COG2267	carboxylic ester hydrolase activity
CP981_RS32590	COG3958	Transketolase
CP981_RS32595	COG3959	Transketolase, thiamine diphosphate binding domain
CP981_RS32625	COG2124	cytochrome p450
CP981_RS32630	COG1686	Belongs to the peptidase S11 family
CP981_RS32650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP981_RS32655	COG3246	L-lysine catabolic process to acetate
CP981_RS32670	COG0174	glutamine synthetase
CP981_RS32690	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS32725	COG1960	acyl-CoA dehydrogenase activity
CP981_RS32745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS32750	COG2706	6-phosphogluconolactonase activity
CP981_RS32770	COG5183	chlorophyll binding
CP981_RS32770	COG2133	pyrroloquinoline quinone binding
CP981_RS32830	COG3537	Alpha-1,2-mannosidase
CP981_RS32855	COG0583	DNA-binding transcription factor activity
CP981_RS32880	COG0531	amino acid
CP981_RS32885	COG3360	Dodecin
CP981_RS32930	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP981_RS32935	COG0121	glutamine amidotransferase
CP981_RS32940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP981_RS32945	COG3572	ergothioneine biosynthetic process
CP981_RS32965	COG1388	LysM domain
CP981_RS32965	COG3858	chitin binding
CP981_RS32975	COG1960	acyl-CoA dehydrogenase activity
CP981_RS32980	COG1960	acyl-CoA dehydrogenase activity
CP981_RS33015	COG0445	tRNA wobble uridine modification
CP981_RS33025	COG4221	oxidoreductase activity
CP981_RS33035	COG0604	alcohol dehydrogenase
CP981_RS33035	COG3321	synthase
CP981_RS33040	COG3321	synthase
CP981_RS33040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS33050	COG0596	Alpha beta hydrolase
CP981_RS33070	COG3511	phospholipase C
CP981_RS33080	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP981_RS33080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP981_RS33100	COG3023	N-Acetylmuramoyl-L-alanine amidase
CP981_RS33105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS33105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS33110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS33115	COG1940	carbohydrate kinase activity
CP981_RS33120	COG1070	Carbohydrate kinase
CP981_RS33130	COG3458	cephalosporin-C deacetylase activity
CP981_RS33145	COG0765	amino acid transport
CP981_RS33150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP981_RS33155	COG2040	homocysteine
CP981_RS33170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP981_RS33195	COG2226	methyltransferase
CP981_RS33210	COG2018	Roadblock/LC7 domain
CP981_RS33220	COG1946	Acyl-CoA thioesterase
CP981_RS33245	COG1819	glycosyl
CP981_RS33250	COG3973	AAA domain
CP981_RS33260	COG1132	(ABC) transporter
CP981_RS33265	COG1132	(ABC) transporter
CP981_RS33305	COG1132	(ABC) transporter
CP981_RS33315	COG0242	peptide deformylase activity
CP981_RS33360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP981_RS33365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP981_RS33380	COG0477	Major facilitator Superfamily
CP981_RS33395	COG2018	Roadblock/LC7 domain
CP981_RS33410	COG2072	flavoprotein involved in K transport
CP981_RS33430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP981_RS33435	COG0432	Pfam Uncharacterised protein family UPF0047
CP981_RS33480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS33500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS33505	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP981_RS33510	COG3251	PFAM MbtH domain protein
CP981_RS33515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS33520	COG3903	Transcriptional regulator
CP981_RS33520	COG3629	intracellular signal transduction
CP981_RS33530	COG1191	sigma factor activity
CP981_RS33545	COG0243	molybdopterin cofactor binding
CP981_RS33580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP981_RS33630	COG1396	sequence-specific DNA binding
CP981_RS33665	COG2124	cytochrome p450
CP981_RS33665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CP981_RS33710	COG1720	tRNA m6t6A37 methyltransferase activity
CP981_RS33770	COG2814	Major facilitator Superfamily
CP981_RS33785	COG1473	amidohydrolase
CP981_RS33795	COG3291	Pkd domain containing protein
CP981_RS33800	COG0583	DNA-binding transcription factor activity
CP981_RS33820	COG2018	Roadblock/LC7 domain
CP981_RS33850	COG1846	Transcriptional regulator
CP981_RS33885	COG2080	2 iron, 2 sulfur cluster binding
CP981_RS33890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP981_RS33895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS33910	COG1254	Belongs to the acylphosphatase family
CP981_RS33925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP981_RS33935	COG2271	Major facilitator Superfamily
CP981_RS33940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP981_RS33945	COG1304	FMN binding
CP981_RS33960	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS33970	COG4213	ABC transporter substrate-binding protein
CP981_RS33985	COG2706	6-phosphogluconolactonase activity
CP981_RS34005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP981_RS34015	COG1902	pentaerythritol trinitrate reductase activity
CP981_RS34050	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS34065	COG0326	Molecular chaperone. Has ATPase activity
CP981_RS34085	COG1113	amino acid transport
CP981_RS34095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP981_RS34115	COG1252	NADH dehydrogenase
CP981_RS34125	COG1335	isochorismatase
CP981_RS34145	COG0477	Major facilitator Superfamily
CP981_RS34150	COG1957	nucleoside hydrolase
CP981_RS34155	COG1609	Transcriptional regulator
CP981_RS34220	COG4166	transmembrane transport
CP981_RS34230	COG2205	protein histidine kinase activity
CP981_RS34245	COG3961	Belongs to the TPP enzyme family
CP981_RS34250	COG1231	oxidoreductase activity
CP981_RS34325	COG1309	transcriptional regulator
CP981_RS34345	COG0504	CTP synthase activity
CP981_RS34385	COG0531	amino acid
CP981_RS34420	COG2197	response regulator
CP981_RS34455	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CP981_RS34485	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS34505	COG0367	asparagine synthase
CP981_RS34515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS34535	COG3629	intracellular signal transduction
CP981_RS34540	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP981_RS34555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP981_RS34580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS34605	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS34620	COG1960	acyl-CoA dehydrogenase activity
CP981_RS34645	COG1228	amidohydrolase
CP981_RS34655	COG1216	Glycosyl transferase, family 2
CP981_RS34670	COG2270	Major facilitator Superfamily
CP981_RS34685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP981_RS34700	COG3012	SEC-C Motif Domain Protein
CP981_RS34710	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP981_RS34730	COG2356	endonuclease I
CP981_RS34735	COG1686	Belongs to the peptidase S11 family
CP981_RS34740	COG1278	Cold shock
CP981_RS34765	COG0702	epimerase
CP981_RS34770	COG0739	heme binding
CP981_RS34805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS34815	COG1846	Transcriptional regulator
CP981_RS34820	COG1764	response to oxidative stress
CP981_RS34825	COG2723	6-phospho-beta-galactosidase activity
CP981_RS34830	COG0395	ABC-type sugar transport system, permease component
CP981_RS34835	COG1175	transmembrane transport
CP981_RS34845	COG1940	carbohydrate kinase activity
CP981_RS34865	COG2770	Histidine kinase
CP981_RS34865	COG2208	phosphoserine phosphatase activity
CP981_RS34905	COG1968	undecaprenyl-diphosphatase activity
CP981_RS34920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP981_RS35010	COG0110	maltose O-acetyltransferase activity
CP981_RS35030	COG1832	CoA-binding protein
CP981_RS35040	COG1739	Uncharacterized protein family UPF0029
CP981_RS35050	COG0420	3'-5' exonuclease activity
CP981_RS35055	COG0419	ATPase involved in DNA repair
CP981_RS35060	COG1522	sequence-specific DNA binding
CP981_RS35065	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS35090	COG1595	DNA-templated transcription, initiation
CP981_RS35100	COG2188	Transcriptional regulator
CP981_RS35105	COG1940	carbohydrate kinase activity
CP981_RS35125	COG3511	phospholipase C
CP981_RS35135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP981_RS35145	COG2313	pseudouridylate synthase activity
CP981_RS35155	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CP981_RS35160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP981_RS35175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP981_RS35275	COG1309	transcriptional regulator
CP981_RS35315	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS35350	COG2226	methyltransferase
CP981_RS35355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP981_RS35360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP981_RS35365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP981_RS35380	COG0583	DNA-binding transcription factor activity
CP981_RS35385	COG1280	lysine exporter protein (LysE YggA)
CP981_RS35405	COG0740	serine-type endopeptidase activity
CP981_RS35420	COG0831	urea catabolic process
CP981_RS35425	COG0832	Belongs to the urease beta subunit family
CP981_RS35430	COG0804	urea catabolic process
CP981_RS35435	COG0830	nickel cation binding
CP981_RS35440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP981_RS35445	COG0829	nickel cation binding
CP981_RS35500	COG3336	cytochrome c oxidase
CP981_RS35505	COG0205	6-phosphofructokinase activity
CP981_RS35510	COG3442	glutamine amidotransferase
CP981_RS35520	COG0242	peptide deformylase activity
CP981_RS35530	COG1960	acyl-CoA dehydrogenase activity
CP981_RS35540	COG3960	tartronate-semialdehyde synthase activity
CP981_RS35545	COG2084	Dehydrogenase
CP981_RS35560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP981_RS35570	COG1028	Short-chain dehydrogenase reductase Sdr
CP981_RS35585	COG0477	Major facilitator Superfamily
CP981_RS35595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS35600	COG2186	Transcriptional regulator
CP981_RS35605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP981_RS35620	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CP981_RS35650	COG0375	protein maturation
CP981_RS35655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP981_RS35660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP981_RS35665	COG0298	carbon dioxide binding
CP981_RS35670	COG0409	Hydrogenase expression formation protein
CP981_RS35680	COG2837	iron assimilation
CP981_RS35690	COG0531	amino acid
CP981_RS35705	COG1793	dna ligase
CP981_RS35725	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS35745	COG3290	protein histidine kinase activity
CP981_RS35755	COG1349	DNA-binding transcription factor activity
CP981_RS35765	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CP981_RS35790	COG2124	cytochrome p450
CP981_RS35850	COG1846	Transcriptional regulator
CP981_RS35865	COG0583	DNA-binding transcription factor activity
CP981_RS35875	COG0339	signal peptide processing
CP981_RS35885	COG1652	LysM domain
CP981_RS36000	COG0574	Belongs to the PEP-utilizing enzyme family
CP981_RS36000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP981_RS36030	COG2301	Belongs to the HpcH HpaI aldolase family
CP981_RS36070	COG0297	glycogen (starch) synthase activity
CP981_RS36080	COG0110	maltose O-acetyltransferase activity
CP981_RS36085	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP981_RS36090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP981_RS36095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP981_RS36145	COG2409	Drug exporters of the RND superfamily
CP981_RS36160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP981_RS36185	COG0328	RNA-DNA hybrid ribonuclease activity
CP981_RS36225	COG2197	response regulator
CP981_RS36230	COG4585	Histidine kinase
CP981_RS36260	COG0477	Major facilitator Superfamily
CP981_RS36265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP981_RS36270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP981_RS36275	COG0142	geranyltranstransferase activity
CP981_RS36295	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP981_RS36310	COG1595	DNA-templated transcription, initiation
CP981_RS36350	COG2080	2 iron, 2 sulfur cluster binding
CP981_RS36355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP981_RS36360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP981_RS36365	COG0431	NADPH-dependent FMN reductase
CP981_RS36405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP981_RS36405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP981_RS36410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP981_RS36410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP981_RS36435	COG2252	PERMEase
CP981_RS36455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP981_RS36455	COG1017	nitric oxide dioxygenase activity
CP981_RS36460	COG1959	2 iron, 2 sulfur cluster binding
CP981_RS36475	COG0596	Alpha beta hydrolase
CP981_RS36495	COG0537	adenosine 5'-monophosphoramidase activity
CP981_RS36510	COG1088	dTDP-glucose 4,6-dehydratase activity
CP981_RS36515	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CP981_RS36530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP981_RS36535	COG0247	lactate metabolic process
CP981_RS36535	COG0277	FAD linked oxidase domain protein
CP981_RS36540	COG0583	DNA-binding transcription factor activity
CP981_RS36545	COG0531	amino acid
CP981_RS36550	COG0583	DNA-binding transcription factor activity
CP981_RS36585	COG2208	phosphoserine phosphatase activity
CP981_RS36585	COG2770	Histidine kinase
CP981_RS36590	COG4257	antibiotic catabolic process
CP981_RS36595	COG1191	sigma factor activity
CP981_RS36700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP981_RS36725	COG1132	(ABC) transporter
CP981_RS36740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP981_RS36745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP981_RS36785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP981_RS36790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS36790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP981_RS36820	COG4585	Histidine kinase
CP981_RS36855	COG3979	chitinase
CP981_RS36870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP981_RS36890	COG3938	Belongs to the proline racemase family
CP981_RS36895	COG1012	belongs to the aldehyde dehydrogenase family
CP981_RS36900	COG1802	Transcriptional regulator
CP981_RS36925	COG0789	Transcriptional regulator
CP981_RS36930	COG1902	pentaerythritol trinitrate reductase activity
CP981_RS36955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP981_RS36970	COG1231	oxidoreductase activity
CP981_RS36980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP981_RS37005	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP981_RS37045	COG0494	nUDIX hydrolase
CP981_RS37055	COG0318	PFAM AMP-dependent synthetase and ligase
CP981_RS37090	COG2192	nodulation
CP981_RS37095	COG1595	DNA-templated transcription, initiation
CP981_RS37100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP981_RS37110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP981_RS37125	COG3396	Phenylacetate-CoA oxygenase
CP981_RS37135	COG3396	Phenylacetate-CoA oxygenase
CP981_RS37140	COG2151	metal-sulfur cluster biosynthetic enzyme
CP981_RS37270	COG5635	Nacht domain
CP981_RS37270	COG2319	Wd-40 repeat
CP981_RS37375	COG3209	COG3209 Rhs family protein